ライフサイエンスコーパス: neurochemical

1 pH shifts but not to other commonly studied neurochemicals.

2 tection of other catecholamines and phenolic neurochemicals.

3 ould be useful for the in vivo monitoring of neurochemicals.

4 er, few studies have examined functional and neurochemical abnormalities specifically in the rostral

5 ostimulants are devoid of the behavioral and neurochemical actions that define this class of drugs an

6 d suggest a new mechanism to disrupt cocaine neurochemical actions.

7 ndent pathway that modulates cocaine-induced neurochemical activity in the mesolimbic system.

8 d whether the mPOA modulates cocaine-induced neurochemical activity in the nucleus accumbens.

9 rm, WINCS Harmoni, which can measure in vivo neurochemical activity simultaneously across multiple an

10 clinical findings on the neuroanatomical and neurochemical adaptations triggered by prolonged pain st

11 a-related metabolites.SIGNIFICANCE STATEMENT Neurochemical ageing is an integral component of age-rel

12 an that for brain structural (P < 0.001) and neurochemical alterations (P < 0.001), while the summary

13 P = 0.14), neurophysiological (P = 0.54), or neurochemical alterations (P = 0.22).

14 diabetes, may be risk factors for prefrontal neurochemical alterations in BD.

15 ated relevant dopaminergic and glutamatergic neurochemical alterations in the cortex and the striatum

16 In addition, we probed for neurochemical alterations in the glutamatergic circuitry

17 ce before reviewing normative structural and neurochemical alterations that persist until early adult

18 We supplement these data with anatomical and neurochemical analyses of nonrecorded L-ITCcs.

19 anning electrochemical microscopy (SECM) and neurochemical analysis inside single cells.

20 Behavior and neurochemical analysis suggests that the effects of alco

21 Their complex neurochemical anatomy has been studied extensively in gu

22 asis is given to a comprehensive functional, neurochemical and anatomical classification of GABAergic

23 Given the neurochemical and anatomical heterogeneity of the BF, we

24 ce, which lack D-serine, exhibit many of the neurochemical and behavioral abnormalities observed in S

25 To evaluate IS impact on neurochemical and behavioral alterations, we examined it

26 tegrin beta3 recapitulates the sex-dependent neurochemical and behavioral attributes of ASD.

27 the prophylactic effect of ketamine against neurochemical and behavioral changes that follow inescap

28 trast agents (GBCAs) for enhanced MRI, their neurochemical and behavioral consequences, if any, remai

29 onergic attenuation of cocaine abuse-related neurochemical and behavioral effects.

30 Both of these effects, neurochemical and behavioral, were most pronounced durin

31 and stimulus intensity, we measured combined neurochemical and BOLD signals (combined fMRI-MRS) to di

32 discuss advances in our understanding of the neurochemical and cellular heterogeneity of LHA neurons

33 Understanding the underlying neurochemical and connectivity-based brain mechanisms of

34 ulate not only affective state, but also the neurochemical and downstream neurophysiological environm

35 model of inflammation was used to assess the neurochemical and functional changes induced by inflamma

36 Our data suggest a new view into the neurochemical and functional properties of BAT-related P

37 tudies in non-human primates, where targeted neurochemical and genetic manipulations can be made, are

38 We investigated the relationship between neurochemical and hemodynamic responses as a function of

39 development and characterize the behavioral, neurochemical and metabolic phenotypes.

40 ting stress-related behaviors and associated neurochemical and microbiota changes, opening possible n

41 states require the coordination of multiple neurochemical and modulatory systems.

42 We also discuss some of the stress-induced neurochemical and molecular alterations in these brain r

43 tions of the MCH system, and that particular neurochemical and morphological features may have been d

44 s to environmental cues, personality traits, neurochemical and pharmacogenetic differences.

45 ogical changes in patients by brain imaging, neurochemical and pharmacological approaches.

46 eal-time simultaneous monitoring of multiple neurochemicals and direct-current electrocorticography (

47 gest alteration of developmentally important neurochemicals and lateral ventricle dilation may be mec

48 gical mechanisms using electrophysiological, neurochemical, and behavioral procedures.

49 This relationship was component, neurochemical, and brain region specific.

50 somers and employed a battery of behavioral, neurochemical, and electrophysiological procedures to as

51 These results demonstrate anatomical, neurochemical, and task specificity and suggest that vis

52 y sugar increases TCA cycle activity, alters neurochemicals, and depletes 1-carbon metabolism and bra

53 BLA by using a combination of anatomical and neurochemical approaches.

54 However, whether levels of these neurochemicals are abnormal in epileptic patients is unk

55 its of quantitation suitable for determining neurochemicals at physiologically relevant levels.

56 ent neurochemical systems, and also that the neurochemical bases for food and touch rewards are not i

57 been developed to investigate the neural and neurochemical bases of different types of cost/benefit d

58 reasingly well characterized, the underlying neurochemical bases of individual differences in reading

59 Importantly, they may also provide a neurochemical basis for therapeutic effects as witnessed

60 highlight the state- and practice-dependent neurochemical basis of human brain dynamics.

61 These findings also shed light on the neurochemical basis of individual susceptibility to valu

62 s in psychosis, and potentially indicating a neurochemical basis to stratify psychosis.

63 lities in CNS disorders and their underlying neurochemical basis.

64 One of the putative neurochemical biomarkers for depression in major depress

65 onships between Hg and Se concentrations and neurochemical biomarkers in different brain regions of b

66 ((1)H-MRS) has been used to assess regional neurochemical brain changes during normal ageing, but re

67 st sensitive (eg, interpersonal dynamics and neurochemical change) and the individual variability in

68 R spectroscopy ((1)H-MRS) studies of in vivo neurochemical changes across the lifespan have, however,

69 us to compare the relationship between these neurochemical changes and the physiological and peripher

70 f tolerance and dependence, and assessed for neurochemical changes associated with prolonged treatmen

71 dicate a sensitivity threshold for detecting neurochemical changes during visual processing.

72 ontribute to the trait anxious phenotype via neurochemical changes in brain areas implicated in inter

73 ss of the 10 mug/g threshold associated with neurochemical changes in Chiroptera conspecifics (n = 26

74 s do not take advantage of real-time in vivo neurochemical changes in dynamic brain processes such as

75 Neurochemical changes in motor areas of the brain are as

76 e with Parkinson's disease can show premotor neurochemical changes in the dopaminergic and non-dopami

77 Neurochemical changes in the expression of various prote

78 ts brain function by inducing structural and neurochemical changes in the hippocampus and related med

79 aine use disorder (CUD), suggesting possible neurochemical changes in the putamen, which may contribu

80 on and leads to multiple local molecular and neurochemical changes in the raphe nuclei that dysregula

81 Given the known neurochemical changes in the serotonergic system and the

82 t of most agents and the need to explain how neurochemical changes reverse the many different symptom

83 A better understanding of the neurochemical changes that occur during the progression

84 cts of BAY on memory performance and related neurochemical changes were partially blocked by the PKG

85 The neurochemical characteristics and distributions of pepti

86 e goal of this study was to provide detailed neurochemical characterization of mouse celiac ganglia a

87 eous WAT and interscapular BAT, coupled with neurochemical characterization of specific cell populati

88 Neurochemical characterization of these ZI neurons revea

89 Concentrations of neurochemicals choline and myo-inositol that were higher

90 from the within-system dysregulation of key neurochemical circuits that mediate incentive-salience a

91 gdalar pathway innervated preferentially the neurochemical classes of calbindin and calretinin neuron

92 ew PPE positive catecholaminergic neuron but neurochemical codes were largely unidentified.

93 external environment can be used to overcome neurochemical communication deficits in this important b

94 Similarities on the cellular and neurochemical composition of the amygdaloid subnuclei su

95 The neurochemical composition of this region is complex, con

96 how TBI changes the metabolism of essential neurochemical compounds, summarize how neuroimaging appr

97 ce spectroscopic imaging to measure cerebral neurochemical concentrations (N-acetylaspartate, choline

98 These results suggest that neurochemical concentrations are maintained at lower ran

99 normalities in cerebral blood flow, cerebral neurochemical concentrations, and white matter integrity

100 electrophysiological characteristics lacking neurochemical confirmation.

101 This neurochemical connectivity database (ChemNetDB) is suppo

102 Understanding the rat neurochemical connectome is fundamental for exploring ne

103 investigations into a multiscale, multilayer neurochemical connectome of the rat brain.

104 have been used extensively to determine the neurochemical consequences of chronic ethanol exposure,

105 holaminergic neurons are activated and other neurochemical content is largely unknown hence whether s

106 al of the present study was to determine the neurochemical content, innervations, and distribution of

107 d negative affective states, wherein several neurochemicals converge and interact to coordinate diver

108 These results identify a neurochemical correlate for a laboratory drug-seeking pa

109 ing effects of neuropeptide Y (NPY), another neurochemical correlate of arousal, and potentiates NPY'

110 Our study is the first one to show a neurochemical correlate to the parasympathetic role of t

111 The results provide initial insight into the neurochemical correlates of cortical plasticity associat

112 vely and comparatively assessed to elucidate neurochemical correlates to their divergent behavioral p

113 Exercise attenuates methamphetamine-induced neurochemical damage in the rat brain, and a preliminary

114 They demonstrate structural, functional, and neurochemical deficits in both major neuronal types that

115 over other rewarding activities, and exhibit neurochemical deficits related to dopamine, which is inv

116 From initial models centered on neurochemical deficits, such as the monoamine hypothesis

117 great significance for studying and treating neurochemical diseases due to its potential feasibility

118 al neurons of mouse celiac ganglia have less neurochemical diversity than reported for guinea pig and

119 c acid during the biosynthesis of the potent neurochemicals domoic acid and kainic acid.

120 sed in selective detection and estimation of neurochemical dopamine by electrochemical method.

121 ty of molecular fMRI for characterization of neurochemical dynamics.

122 o a collection of studies that have examined neurochemical (e.g., glutamatergic and gamma-aminobutyri

123 ly bears sampled had Hg levels exceeding the neurochemical effect level proposed for polar bears.

124 This neurochemical effect was thought to require inhibition o

125 The detrimental behavioral and neurochemical effects of adolescent stress, as well as t

126 ly mediated behavioral, transcriptional, and neurochemical effects of MAOIs.

127 ficits in motor function, and alterations in neurochemical effects of nicotine.

128 eks before a stressor, blunts behavioral and neurochemical effects of the stressor.

129 inhibitor scaffold for preventing the deadly neurochemical effects of the toxin.

130 opamine transmission, we performed anatomic, neurochemical, electrophysiologic, and behavioral invest

131 identify biological cascades involved in the neurochemical, electrophysiological, and behavioral effe

132 a complex interplay of genetic, epigenetic, neurochemical, endocrine, and inflammatory contributors,

133 e-induced dopamine release in the NAc, a key neurochemical event contributing to methamphetamine addi

134 that these neuroadaptations represent a key neurochemical event in compulsive drug use and relapse.

135 l similarity index (SSIM), to identify rapid neurochemical events.

136 Previous neurochemical evidence may be reinterpreted in terms of

137 ings together physiological, behavioral, and neurochemical evidence to examine variability in the exc

138 treatment regimen, electrophysiological and neurochemical experiments were performed to assess possi

139 discrete subregions based on dichotomies in neurochemical expression or connectivity.

140 Although general anatomical and neurochemical features of hypothalamic neurons were desc

141 a better understanding of the anatomical and neurochemical features of this pathway.

142 ddition, WINCS Harmoni can provide real-time neurochemical feedback for closed-loop control of neuroc

143 A striking neurochemical form of compartmentalization has been foun

144 tility of combining fMRI and PET measures of neurochemical function to advance our understanding of b

145 Historically, brain neurochemicals have been broadly classified as energetic

146 The cellular and neurochemical heterogeneity of the mPFC and its projecti

147 ined this issue with an appreciation for the neurochemical heterogeneity of these nuclei.

148 it hinders the restoration of behavioral and neurochemical homeostasis after stress cessation.SIGNIFI

149 Neuropeptides are an important class of neurochemicals; however, measuring their concentration i

150 PVH, we performed a detailed analysis of the neurochemical identity of GH-responsive cells to underst

151 d the detailed morphology, connectivity, and neurochemical identity of neurons in these nuclei.

152 In this study, in chicks, we revise the neurochemical identity of the isthmic nuclei by using in

153 However, the neurochemical identity of the majority of these VLPO-pro

154 opic axis provides an important exception in neurochemical identity, however, as pituitary prolactin

155 satiety with peptide YY3-36 can reverse this neurochemical imbalance and acutely restore sleep compos

156 lthough the depletion of dopamine is the key neurochemical impairment in PD and anticholinergic medic

157 ex interactions within the multicellular and neurochemical in vivo milieu.

158 itate voltammetric detection of redox active neurochemicals in a multianalyte solution.

159 raphene electrodes to dopamine and serotonin neurochemicals in fast-scan cyclic voltammetry measureme

160 toolbox for measurements of local levels of neurochemicals in multiple brain systems implicated in t

161 ch they act, in vivo measurement of multiple neurochemicals in the brain remains a challenge.

162 The most diverse and versatile neurochemicals in the insect nervous system are found in

163 selective for detecting rapidly fluctuating neurochemicals in vivo; however, many challenges exist f

164 ectrometry revealed reliable detection of 14 neurochemicals, including dopamine and acetylcholine, at

165 NAc) in the ventral striatum integrates many neurochemical inputs including dopamine and serotonin pr

166 m several brain areas which provide multiple neurochemical inputs to the LC with changes in LC neuron

167 e relationships improve our understanding of neurochemical interactions in prefrontostriatal circuits

168 ite levels may provide biomarkers for future neurochemical interventions by pharmacologic or other me

169 d is often utilized for targeted delivery in neurochemical investigations.

170 en employed as a method of drug delivery for neurochemical investigations.

171 ship member of the kainoid family of natural neurochemicals, is a widely used neuropharmacological ag

172 Neurochemical levels did not change in patients with sta

173 Slopes of neurochemical levels over time were compared between pat

174 chemical feedback for closed-loop control of neurochemical levels via its synchronized stimulation an

175 fic BNST neuronal types and their associated neurochemical makeup.

176 These preliminary findings suggest that a neurochemical marker of ASD may be present very early in

177 Neurochemical markers of amyotrophic lateral sclerosis (

178 There are few neurochemical markers that reliably identify retinal gan

179 This study utilizes several neurochemical markers that reveal an emerging LCIC modul

180 bly of cell populations typically defined by neurochemical markers, such as the well-described neurop

181 dules that stain for GAD-67 as well as other neurochemical markers.

182 ive input from nerves expressing an array of neurochemical markers.

183 The composite neurochemical measure, myo-inositol+glycine/creatine, wa

184 which these associations, involving a single neurochemical measure, reflect more general effects of d

185 To assess incentive learning, behavioral and neurochemical measurements were made during the acquisit

186 in the central nervous system (CNS) is a key neurochemical mechanism involved in social bonding, part

187 ivity by social laughter may be an important neurochemical mechanism reinforcing and maintaining soci

188 release after social laughter may provide a neurochemical mechanism supporting long-term relationshi

189 The current study investigated the neurochemical mechanism underlying semantic processing i

190 The current study examined the neurochemical mechanisms and neuroanatomical changes und

191 findings provide novel insight into cortical neurochemical mechanisms contributing to increased impul

192 Understanding the neurochemical mechanisms mediating the prosocial effects

193 ioral function, computational algorithm, and neurochemical mechanisms of an object-selective neuron,

194 he continuous performance task use different neurochemical mechanisms subserving motor response inhib

195 However, the neurochemical mechanisms underlying the attentional prio

196 However, the neurochemical mechanisms underlying this presymptomatic

197 Sex differences exist in the neurochemical mechanisms underlying tobacco smoking and

198 g brain microstructure, gene expression, and neurochemical metabolism across regions of the amygdala,

199 NRA neurochemical microstimulation also generated vocalizati

200 Neurochemical microstimulation in different parts of the

201 o substantiate the link between the cortical neurochemical milieu, the tuning of cortical activity, a

202 Further, a neurochemical mimic of the light input pathway evoked la

203 ignaling and by enhanced responsiveness to a neurochemical mimic of the light input pathway to the SC

204 Here we developed a neurochemical model of dopamine receptor binding taking

205 ol the behavioral, electrophysiological, and neurochemical modifications caused by chronic unpredicta

206 colliculus exhibits connectional as well as neurochemical modularity and may contain multiple segreg

207 se relationships in older adults, suggesting neurochemical modulation of cognitive flexibility change

208 atially related to the distribution of these neurochemical modules.

209 Neurochemical monitoring for long timescales is necessar

210 is sampling is an essential tool for in vivo neurochemical monitoring.

211 other integration hubs, it contains repeated neurochemical motifs with distinct inputs: GABA-rich mod

212 However, the neurochemical nature of the ATL in the semantic processi

213 s examined neuronal activation using Fos and neurochemical/neuroreceptor profiles on brain areas invo

214 d (+)-naltrexone, did not specifically block neurochemical or behavioral abuse-related effects of coc

215 tectable cognitive or motor deficits, and no neurochemical or biochemical evidence of injury in the s

216 lutathione (GSH), may associate with central neurochemicals or neuropsychological performance in heal

217 s to firstly, visualize and quantify the STN neurochemical organization based on neuronal markers inc

218 The functional and neurochemical organization of the central complex has be

219 he data provide additional insights into the neurochemical organization of the locust central complex

220 lic alterations was significantly lower than neurochemical (P = 0.04), neurophysiological (P < 0.001)

221 on brain structural, neurophysiological, and neurochemical parameters) and non-CNS dysfunction (focus

222 elease after social laughter would provide a neurochemical pathway supporting long-term relationships

223 ivity by social laughter may be an important neurochemical pathway that supports the formation, reinf

224 icals, has the potential to modulate several neurochemical pathways implicated in depression.

225 Neurochemical pathways involved in pathological overeati

226 Furthermore, we demonstrate how neurochemical pathways of BDNF and FGF2, through the MAP

227 However, elaboration of the neurochemical pathways that govern aggression has proven

228 However, the neurochemical phenotype and connectivity of BNST RXFP3-e

229 This neurochemical phenotype appears to be plastic as exposur

230 ts reveal an unusual phenomenon in which the neurochemical phenotype of dopaminergic neurons is not l

231 Scope and immunofluorescence to identify the neurochemical phenotype of the projecting neurons.

232 xamined for tracer distribution and neuronal neurochemical phenotype.

233 rculation little is known of the origins and neurochemical phenotypes of the parasympathetic innervat

234 vagal afferent neurons express two different neurochemical phenotypes that can inhibit or stimulate f

235 ketamine occurs, in part, by reversing these neurochemical/physiological disturbances.

236 ncluding its spatial relationship to another neurochemical population of the tuberal hypothalamus, th

237 ines in the pathophysiology of SCZ and major neurochemical postulates of the disorder, including the

238 s are currently detected by several types of neurochemical probes ranging from microdialysis-based to

239 er task performance and imply that GABAergic neurochemical processes are potentially crucial to the n

240 in these behaviors will improve knowledge of neurochemical processes that regulate flexible decision-

241 tters, suggesting an influence of dopegal on neurochemical processes.

242 ole: overlearning in humans abruptly changes neurochemical processing, to hyperstabilize and protect

243 e formed by intrinsic enteric neurons with a neurochemical profile consistent with IPANs and have dir

244 as changes in activation, connectivity, and neurochemical profile in their missing hand's cortical t

245 The electrophysiological properties and neurochemical profile of CSNs revealed an increase of no

246 we characterized the pattern of projections, neurochemical profile, and genoarchitecture of Pul-T cel

247 Their soma size, neurochemical profile, and peripheral and central target

248 veness to noxious peripheral stimulation and neurochemical profile.

249 mmation generates a pain state with a unique neurochemical profile.

250 hemistry to determine their molecular and/or neurochemical profile.

251 uality spectra enabled the quantification of neurochemical profiles consisting of at least eight meta

252 We suggest that neurochemical profiles of GluCEST contrast across cortex

253 rsity of other cell populations with complex neurochemical profiles that include neuropeptides, recep

254 he proportion of WMICs exhibiting inhibitory neurochemical profiles was ~26%, similar to that observe

255 nd multi-site recordings in combination with neurochemical profiling, we observed a predominant inhib

256 Therefore, we investigated the neurochemical properties of GABAergic interneurons in th

257 dulate in real time electrophysiological and neurochemical properties of mesencephalic dopaminergic (

258 ctonical markers, as well as hodological and neurochemical properties that match specifically those o

259 d cells preserved cortical morphological and neurochemical properties.

260 eir morphological, electrophysiological, and neurochemical properties.

261 Here we report an integrated neurochemical recording platform for monitoring dopamine

262 reveal the precise mechanisms by which these neurochemicals regulate healthy and diseased neural circ

263 However, whether estradiol enhances the neurochemical response to cocaine by acting in the mPOA

264 BI patients with time-locked analysis of the neurochemical response to seizures and pseudoperiodic di

265 Elucidation of taurine's neurochemical roles and importance would be substantiall

266 levels via its synchronized stimulation and neurochemical sensing capabilities.

267 Thus, cavity CNPEs are promising neurochemical sensors that provide spatial resolution on

268 ments will help improve our understanding of neurochemical signaling in Drosophila.

269 separate electrodes and animals to evaluate neurochemical signals in multiple subjects.

270 These results suggest that hemodynamic and neurochemical signals reflect common metabolic markers o

271 OCD, we examined effective connectivity and neurochemical signatures in the pregenual anterior cingu

272 DGFRalpha/beta levels, reduced levels of the neurochemical SP, a reduction in CGRP fibers and changes

273 These results show anatomical and neurochemical specificity and are replicated in an indep

274 In our study, we characterized the neurochemical specificity, somatodendritic morphology, s

275 ctivity of neurons and astrocytes with their neurochemical state.

276 s of the emotional voalizations generated by neurochemical stimulation in the PAG.

277 ic hotspots are brain sites where particular neurochemical stimulations causally amplify the hedonic

278 We report here a detailed neurochemical, structural and physiological characteriza

279 he same field are characterised by a similar neurochemical structure and spectral resolution.

280 In psychotic patients, neurochemical studies have confirmed subcortical striata

281 Electrophysiological and neurochemical studies implicate cholinergic signaling in

282 Neurochemical studies in human aggression point to a mod

283 The neurochemical study of the inferior olive and other prec

284 ulator of neural excitability and one of the neurochemical substrates of sleep.

285 the effects of nicotine withdrawal on these neurochemical substrates.

286 al processing via the release of circulating neurochemicals such as hormones or neuromodulators.

287 hed light on the causal relationship between neurochemical systems and human prosocial behavior and h

288 erotic rewards and yields importance for the neurochemical systems of addictive disorders including g

289 the MC4 receptor (MC4R), also interacts with neurochemical systems that regulate socioemotional behav

290 xperienced pleasure rely on partly different neurochemical systems, and also that the neurochemical b

291 forts have been made to identify alternative neurochemical targets for treatment development in SCZ.

292 Here, we used behavioral, molecular, and neurochemical techniques to characterize the effects of

293 erstand the relationship between MRS-visible neurochemicals, the BOLD signal change, and stimulus int

294 philanthropic funding and malicious uses of neurochemicals) to the environmental (crops for changing

295 ngs redefine patch/matrix beyond traditional neurochemical topography and reveal new principles about

296 To examine the range of inhibitory neurochemical types we used antibodies against parvalbum

297 ators and can respond to stimuli and produce neurochemicals, ultimately influencing the brain-gut-mic

298 formance, but very little is known about the neurochemical underpinnings of individual differences in

299 We investigated the neurochemical underpinnings of this process.

300 a Langmuir isotherm, and detection of other neurochemicals was also characterized, including ascorbi