ライフサイエンスコーパス: neurodevelopment

1 roinjection during distinct periods in early neurodevelopment.

2 ethylation in rat sperm at genes involved in neurodevelopment.

3 o assess the impact of chemical exposures on neurodevelopment.

4 from evolving gene co-expression networks of neurodevelopment.

5 active ADAT2/3 complex is crucial for proper neurodevelopment.

6 for neuritogenesis, neuronal migration, and neurodevelopment.

7 ogenesis and synapse maturation during early neurodevelopment.

8 ms with activity-dependent mechanisms during neurodevelopment.

9 has adverse effects on long-term health and neurodevelopment.

10 role in the regulation of genes critical for neurodevelopment.

11 n ASD-risk genes and genes involved in fetal neurodevelopment.

12 matory response and resulting in deficits in neurodevelopment.

13 e have an essential post-mitotic function in neurodevelopment.

14 modulation of the immune system and improved neurodevelopment.

15 ion exposure to these drugs alters offspring neurodevelopment.

16 g sites for RNA-binding proteins crucial for neurodevelopment.

17 ic mechanisms that specifically affect early neurodevelopment.

18 ne is critical for proper brain function and neurodevelopment.

19 for the key role of Ca(v)2.2 in normal human neurodevelopment.

20 uit is sexually dimorphic and changes across neurodevelopment.

21 C6B and MKL2, regulatory genes with links to neurodevelopment.

22 e activation of key genes required for human neurodevelopment.

23 per tissue remodeling during early stages of neurodevelopment.

24 the effects of intrauterine inflammation on neurodevelopment.

25 renatal acetaminophen exposure may influence neurodevelopment.

26 at regulatory chromatin active during fetal neurodevelopment.

27 ts may affect chromatin accessibility during neurodevelopment.

28 t early life vitamin D is crucial for proper neurodevelopment.

29 adversely impact brain growth and subsequent neurodevelopment.

30 on underlies roles of both proteins in human neurodevelopment.

31 us synthetic chemicals, may adversely affect neurodevelopment.

32 Child stunting reduces survival and impairs neurodevelopment.

33 he critical roles of the dynein-1 complex in neurodevelopment.

34 with sex at birth, birth outcomes, and fetal neurodevelopment.

35 ated microbiota have been shown to influence neurodevelopment.

36 uto-phosphorylation in neuronal function and neurodevelopment.

37 des linking prenatal preeclampsia to altered neurodevelopment.

38 complement proteins in synaptic pruning and neurodevelopment.

39 ways associated with fetal growth to program neurodevelopment.

40 nces of this genetic insult unfold to impair neurodevelopment.

41 d manganese, was evaluated as a predictor of neurodevelopment.

42 he formation of AIS during the early step of neurodevelopment.

43 al a pivotal modulatory role for d-serine in neurodevelopment.

44 is, lipid metabolism, citric acid cycle, and neurodevelopment.

45 ies highlight the important role of Nr2f1 in neurodevelopment.

46 displays dynamic expression during postnatal neurodevelopment.

47 on sequestering and alpha7nAChR signaling in neurodevelopment.

48 intracellular transport, cell division, and neurodevelopment.

49 o prenatal stressors, which adversely impact neurodevelopment.

50 er such perturbation contributes to impaired neurodevelopment.

51 and recruitment could underlie the abnormal neurodevelopment.

52 microorganisms inhabiting the gut influence neurodevelopment.

53 ntal 5-HT levels, forebrain 5-HT levels, and neurodevelopment.

54 ed dynamic m6A modification during postnatal neurodevelopment.

55 ing pregnant rat, which likely affects fetal neurodevelopment.

56 o arsenic, manganese, and lead on children's neurodevelopment.

57 binding and catalytic activity to facilitate neurodevelopment.

58 tent stem cell (iPSC)-derived model of human neurodevelopment.

59 Here, we show that CUL3 is critical for neurodevelopment.

60 et epilepsy syndromes dramatically impairing neurodevelopment.

61 nse to DNA damage-inducing agents and during neurodevelopment.

62 have shown negative associations with child neurodevelopment.

63 on-apoptotic mechanisms of cell death during neurodevelopment.

64 KTs), are implicated in typical and atypical neurodevelopment.

65 omes, including psychopathology and atypical neurodevelopment.

66 al motor biases, its underlying genetics and neurodevelopment.

67 tion of cholesterol biosynthesis compromises neurodevelopment.

68 genetic and environmental factors to impair neurodevelopment.

69 ng this critical period and alters postnatal neurodevelopment.

70 NAs and depletion of transcripts involved in neurodevelopment.

71 th detrimental effects to erythropoiesis and neurodevelopment.

72 ation by a critical neuronal RNA-BP in human neurodevelopment.

73 ata supporting a role for this gene in human neurodevelopment.

74 Cs at a cellular level during early stage of neurodevelopment.

75 ggest that Huntington's disease might affect neurodevelopment.

76 ptic pruning abnormalities that occur during neurodevelopment.

77 cross the cortex express aspects of impaired neurodevelopment after premature birth and lead to reduc

78 lts suggest that by the early teens, typical neurodevelopment allows social influence to systematical

79 ht the need to examine preclinical offspring neurodevelopment alterations in terms of a multifactoria

80 olding protein of significant importance for neurodevelopment and a prominent candidate protein in th

81 helial cells produced offspring with altered neurodevelopment and adult stress reactivity.

82 Immune signaling pathways influence neurodevelopment and are hypothesized to contribute to t

83 luence of prenatal air pollution exposure on neurodevelopment and behavior in 96 children with autism

84 ether early life microbial disruption alters neurodevelopment and behavior in larval zebrafish.

85 t that prenatal exposure to PM(2.5) disrupts neurodevelopment and behavior through complex mechanisms

86 be a valuable resource for future studies of neurodevelopment and behavior.

87 fect of average prenatal PM(2.5) exposure on neurodevelopment and behavioral symptoms, respectively.

88 aternal prenatal stress influences offspring neurodevelopment and birth outcomes including the ratio

89 s in diverse biological processes, including neurodevelopment and cancer progression.

90 immune, and environment factors may modulate neurodevelopment and cause psycho-cognitive deficits.

91 ward understanding BEX family involvement in neurodevelopment and cell death.

92 terature findings of endocrine disruption of neurodevelopment and concomitant changes in behavior by

93 possible link between altered basal ganglia neurodevelopment and declined motor performance in high

94 tergenerational parental stress in offspring neurodevelopment and disease risk, and the currently kno

95 Perspectives Companion Paper: Studying Human Neurodevelopment and Diseases Using 3D Brain Organoids,

96 lustering of genes is bound to evolve during neurodevelopment and disruptions are likely to have a ca

97 Considering CM-HBCD has been implicated in neurodevelopment and endocrine disruption, with expected

98 e pronounced AIM2 inflammasome activation in neurodevelopment and find that defects in this sensor of

99 wed that identified pathways were related to neurodevelopment and highlighted genes linked to axon gu

100 ic effects of As on neural cell function and neurodevelopment and identifies miR-124 as a potential p

101 They influence infant neurodevelopment and immune function, and they provide ~

102 These results reveal a role for ACTL6B in neurodevelopment and implicate another component of chro

103 -derived signals both during early postnatal neurodevelopment and in adult mice, with implications fo

104 infection is a significant cause of abnormal neurodevelopment and long-term neurological sequelae in

105 h factor (NGF) are crucial modulators in the neurodevelopment and maintenance of central and peripher

106 GLRA2, NAA15, PTEN, SYNGAP1 and TPH2 impact neurodevelopment and movement functions, elevating these

107 ophages, exhibit highly dynamic functions in neurodevelopment and neurodegeneration.

108 The role of FTO in neurodevelopment and neurogenesis, however, remains larg

109 opsychiatric diseases is limited to abnormal neurodevelopment and neuronal dysfunction.

110 ct of disruptions of adrenergic signaling in neurodevelopment and neuropathology.

111 RNA editing critically regulates neurodevelopment and normal neuronal function.

112 s should specifically target determinants of neurodevelopment and not simply linear growth.

113 ic as an important regulator of cell fate in neurodevelopment and oligodendroglioma, and suggest that

114 ctory in understanding of activity-regulated neurodevelopment and ongoing neuroplasticity with an arc

115 stem and monocytic cells revealed effects on neurodevelopment and plasticity in neural, immune, and e

116 other indispensable techniques for studying neurodevelopment and plasticity.

117 NA binding and catalytic activity to promote neurodevelopment and prevent mental dysfunction.

118 n the gastrointestinal system, may influence neurodevelopment and programming of social behaviors acr

119 ovel role of placental InsRs in sex-specific neurodevelopment and reveal a potential mechanism for ne

120 te matter deficits that are involved in both neurodevelopment and severity of cognitive deficits in s

121 To compare neurodevelopment and social-emotional development betwee

122 the neurobiological changes associated with neurodevelopment and suggest that characteristics of whi

123 ficient oxidative phosphorylation during the neurodevelopment and suggest that dysfunctional mitochon

124 s study highlights the importance of Cln5 in neurodevelopment and suggests that in contrast to earlie

125 s of TBC1D24 haploinsufficiency to mammalian neurodevelopment and synaptic physiology.

126 CANCE STATEMENT NMDARs are key regulators of neurodevelopment and synaptic plasticity and are unique

127 d phosphatases regulating diverse aspects of neurodevelopment and synaptic plasticity varies accordin

128 otentially by virtue of its critical role in neurodevelopment and synaptic plasticity.

129 ional regulation of specific isoforms during neurodevelopment and the mechanisms behind it remain unk

130 inflammation is thought to underlie aberrant neurodevelopment and to derive from a disruption in intr

131 on co-expression networks, adapted to model neurodevelopment and transfer information from precursor

132 novel mechanistic link of a SZ risk gene to neurodevelopment and translational control.

133 Expression of NT5C2 was higher during neurodevelopment and was neuronally enriched in the adul

134 osure to lead is associated with deficits in neurodevelopment and with hematopoietic system toxicity.

135 Below-average neurodevelopment and/or abnormal eye or hearing assessme

136 is a regulator of host immunity, metabolism, neurodevelopment, and behavior.

137 Cytokines have complex roles in neurodevelopment, and dysregulated levels may be indicat

138 pathway signaling is a major participant in neurodevelopment, and evidence suggests that BRAF, a key

139 on in human brain, implicate PIK3CD in human neurodevelopment, and identify isoform-specific disrupti

140 ers and mediators of growth, bone formation, neurodevelopment, and immune function in children with M

141 tions of genes regulating neurotransmission, neurodevelopment, and immune function, as well as differ

142 been associated with poorer birth outcomes, neurodevelopment, and respiratory function in children.

143 rding disease-relevant variables (cell type, neurodevelopment, and sex), and we ultimately propose ap

144 t may have a unique impact during adolescent neurodevelopment, and subsequently potentially impact ps

145 oncoding disease variants in OCRs can affect neurodevelopment, and that analysis of open chromatin re

146 Early disruptions to neurodevelopment are highly relevant to understanding bo

147 ues to investigate brain function throughout neurodevelopment are limited due to growth in head-size

148 roaches that disregard the dynamic nature of neurodevelopment are limited.

149 The determinants of linear growth and neurodevelopment are only partly shared.

150 s to infants, but its effects on the child's neurodevelopment are unknown.

151 1 (MIB1), an E3 ubiquitin ligase involved in neurodevelopment, as critical for AdV infectivity.

152 so potentially longer-term outcomes, such as neurodevelopment, as well.

153 reterm formula); of survivors, 299 (92%) had neurodevelopment assessed.

154 nal iodine intake in pregnancy and childhood neurodevelopment, assessed using Bayley Scales of Infant

155 wborn Growth Consortium for the 21st Century Neurodevelopment Assessment tool.

156 r milk compared with formula did not improve neurodevelopment at 18 months' corrected age.

157 th a statistically significant difference in neurodevelopment at 2 years of age.

158 To test the hypothesis that neurodevelopment at 4.5 years is related to the severity

159 icient pregnant women had no effect on child neurodevelopment at age 5-6 years.

160 od, placenta and embryo serotonin levels and neurodevelopment at embryonic day E14.5, when peripheral

161 tervention thresholds based on assessment of neurodevelopment at least to school age.

162 tions showed age-appropriate weight gain and neurodevelopment at the age of 12 months.

163 rotein of unknown function, is implicated in neurodevelopment but detailed investigation is lacking.

164 luenced by mitochondrial respiration through neurodevelopment but directly influenced by prenatal PM(

165 nxiety, depression, and stress all influence neurodevelopment but show modest, weak, or no associatio

166 ulates spatiotemporal gene expression during neurodevelopment, but it also mediates DNA damage repair

167 % of human population are linked to atypical neurodevelopment, but predominantly treated by behaviour

168 gest that dysregulation of genes that direct neurodevelopment by common genetic variants may result i

169 sposition can cause somatic mosaicism during neurodevelopment by insertional mutagenesis.

170 refore, Spindly plays a critical role during neurodevelopment by mediating dynein-driven sorting of a

171 on offspring sociability, a proxy for normal neurodevelopment, by studying 203 male macaques in large

172 ant mice (Dys(-/-)) to shed light on retinal neurodevelopment defects in HPS-7.

173 tuses, inducing fetal microcephaly and other neurodevelopment defects.

174 imilar range of adverse effects on childhood neurodevelopment, despite subtle quantitative and qualit

175 ved pleiotropy, including genetic effects on neurodevelopment, diverse actions of regulatory elements

176 r 5 years of age) are at risk of compromised neurodevelopment due to poverty, stunting, and lack of s

177 ether the maternal gut microbiome influences neurodevelopment during critical prenatal periods and in

178 Interventions that directly target neurodevelopment (e.g., early stimulation) or that more

179 regarding the role of the gut-brain axis in neurodevelopment, elucidating the link between MIA, poor

180 ns in diverse biological processes including neurodevelopment, embryogenesis, and tumorigenesis.

181 ans and mice and is associated with impaired neurodevelopment, epilepsy, and hypomyelination.

182 he role of maternal immune activity in fetal neurodevelopment, exacerbated in part by socioeconomic d

183 verse functions of these paralog proteins in neurodevelopment, excitatory synaptic transmission, and

184 igated its effects on the thyroid system and neurodevelopment following maternal exposure from early

185 has been shown to have multiple key roles in neurodevelopment, from axon repulsion to dendrite elabor

186 rrelations between apoptosis, autophagy, and neurodevelopment genes with smaller brain sizes in ADHD,

187 of atypical Rho GTPases (such as RHOBTB2) in neurodevelopment has barely been characterized.

188 in vitro, but its utility for investigating neurodevelopment has remained unclear.

189 igations to understand the protein's role in neurodevelopment have mostly used mouse models with cons

190 ed as a convenient model to study elementary neurodevelopment; however, without in-depth functional a

191 ntal Health: Assessing the Genomic Impact on Neurodevelopment (IMAGINE-ID) study.

192 alization in PD is linked to genes affecting neurodevelopment, immune activation, and synaptic transm

193 ons and placental transfer of manganese with neurodevelopment in 224 2-y-old children residing near t

194 use of potentially neurotoxic pesticides and neurodevelopment in 7-year-old children.

195 adverse findings of e-cigarette exposure on neurodevelopment in a mouse model and provide substantia

196 ces dendritic morphogenesis in two models of neurodevelopment in a region-specific manner has signifi

197 ing maternal stress in pregnancy with infant neurodevelopment in a sexually dimorphic manner are poor

198 se of the National Consortium on Alcohol and Neurodevelopment in Adolescence (NCANDA), and determinin

199 , NCANDA (National Consortium on Alcohol and NeuroDevelopment in Adolescence) study.

200 and colleagues showed evidence for aberrant neurodevelopment in both Huntington's disease (HD) and m

201 d broadband Vis-NIR spectroscopy, to monitor neurodevelopment in brain organoid models that can compl

202 ull associations of prenatal phthalates with neurodevelopment in CHAMACOS, and weak associations of S

203 ciations of prenatal phthalate exposure with neurodevelopment in childhood and adolescence in the Cen

204 neities for modification of exposure-related neurodevelopment in children from the Avon Longitudinal

205 e brain, yet the influence of dysglycemia on neurodevelopment in children with type 1 diabetes remain

206 or hypothyroxinemia associated with impaired neurodevelopment in children.

207 outcomes in women and on immune function and neurodevelopment in children.

208 Lead (Pb) adversely affects neurodevelopment in children.

209 ural use of neurotoxic pesticides and poorer neurodevelopment in children.

210 Arsenic (As) exposure adversely affects neurodevelopment in children.

211 exposure with neural stem cell function and neurodevelopment in children.

212 expression of gene networks associated with neurodevelopment in control animals.

213 A) exposure has been associated with adverse neurodevelopment in epidemiological studies.

214 iding a robust platform for investigation of neurodevelopment in health and disease.

215 elevant cytokine mixtures similarly modulate neurodevelopment in human neurons is not known.

216 s worldwide, and is associated with impaired neurodevelopment in infants and children.

217 This treatment also normalized neurodevelopment in infected mice without significantly

218 ine heterozygous frameshift Chd8 mutation on neurodevelopment in mice.

219 the maternal gut microbiome influences fetal neurodevelopment in mice.

220 eloped a multivariable risk factor model for neurodevelopment in surviving VPT/VLBW children.

221 y highlights the importance of PSD-95 during neurodevelopment in the mPFC and its potential link in t

222 gnancy were associated with poorer childhood neurodevelopment in this iodine-sufficient population.

223 es, and role of the CC as an early marker of neurodevelopment in this unique infant population.

224 noted resolution of microcephaly with normal neurodevelopment in two of eight children, development o

225 s suggest a preadolescent time window within neurodevelopment in which MS risk variants act upon the

226 vitamin B-12 status has been linked to poor neurodevelopment in young children.We measured the assoc

227 edicted functions in chromatin remodeling or neurodevelopment, including ACTL6B, BAZ2B, COL5A3, SSRP1

228 identified significant pathways involved in neurodevelopment, inflammation and intracellular transdu

229 ds do not fully account for lead's impact on neurodevelopment; innovative methods to account for subc

230 ed expression of genes involved in embryonic neurodevelopment: insulin-like growth factor binding pro

231 ciations of prenatal phthalate exposure with neurodevelopment into adolescence, an important time for

232 Neurodevelopment is characterized by rapid rates of neur

233 A long-standing question in neurodevelopment is how neurons develop a single axon an

234 Dysregulation of early neurodevelopment is implicated in macrocephaly/autism di

235 s and neuropsychiatric diseases, its role in neurodevelopment is not well understood.

236 t of maternal diet during pregnancy on child neurodevelopment is of public health and clinical releva

237 he maternal immune system can interfere with neurodevelopment is through maternal autoantibodies that

238 evidence for the genetic basis of childhood neurodevelopment is very limited.

239 of adolescent PTSD, taken in the context of neurodevelopment, is crucial for developing novel and pe

240 hese data highlight a novel role for Akt2 in neurodevelopment, learning and memory and show that Akt2

241 These specific alterations in neurodevelopment may be more likely to affect long-term

242 nsively address the multifactorial nature of neurodevelopment may be required to support healthy deve

243 not yet known whether more subtle effects on neurodevelopment may exist as well.

244 Altered lateralized neurodevelopment may therefore be a feature of ASD, affe

245 al processes taking place in early embryonic neurodevelopment might be responsible for later manifest

246 al history of ZIKV infection, its effects on neurodevelopment, modes and risk of transmission, and it

247 ome members of this family in organogenesis, neurodevelopment, myelination, angiogenesis, and cancer

248 ci implicate biological processes related to neurodevelopment, neuronal excitability, synaptic functi

249 ata indicate potential mechanisms in retinal neurodevelopment of Dys(-/-) mice, which may have transl

250 may provide important information about the neurodevelopment of interoceptive processing abilities i

251 that maternal PCOS may subtly influence the neurodevelopment of the offspring, resulting in increase

252 in mildly iodine-deficient pregnant women on neurodevelopment of their offspring in areas where schoo

253 Three RCTs addressed child neurodevelopment; only 1 was adequately powered.

254 ether these differences result from atypical neurodevelopment or sampling differences between young a

255 , and many function as genetic regulators of neurodevelopment or synaptic proteins that regulate neur

256 amined the association of gene variants with neurodevelopment outcomes in the ELEMENT birth cohort.

257 egnancy plays an important role in offspring neurodevelopment, potentially via epigenetic processes.

258 A young man with normal neurodevelopment presented with 3 years of medically ref

259 As neurodevelopment proceeds, the Pax6 expression changes f

260 e showed exon skipping at exon 7, while nudE neurodevelopment protein 1 (NDE1) gene showed replacemen

261 oncentrations across pregnancy and offspring neurodevelopment proximal to birth is needed to advance

262 d motor domains) in 146 children and through neurodevelopment questionnaires/neurological examination

263 apy engage these targets and restore healthy neurodevelopment remains an open question.

264 nctional diversity in the hypothalamus whose neurodevelopment remains poorly studied.SIGNIFICANCE STA

265 nary dysplasia but its safety with regard to neurodevelopment remains to be assessed.

266 ns are also associated with changes in later neurodevelopment remains to be established.

267 associated with brain structure during early neurodevelopment remains unclear.

268 activation is involved in the regulation of neurodevelopment remains unclear.

269 Neurodevelopment requires precise regulation of gene exp

270 (SD = 4%) and 36% (SD = 3%) of the effect on neurodevelopment, respectively, and that behavior was in

271 can play in the manifestation of changes in neurodevelopment, resulting in the development of neurob

272 tive temporal cortices, folding later during neurodevelopment, revealed that the effect of gyrificati

273 e negatively associated with early childhood neurodevelopment scores in our study.

274 ternal and cord manganese, associations with neurodevelopment scores were negative for pairs with eit

275 nese concentrations were not associated with neurodevelopment scores.

276 es have shown species-specific signatures in neurodevelopment such as the transcriptome of outer-radi

277 in major psychosis converged on pathways of neurodevelopment, synaptic activity, and immune function

278 immune cells of the brain that orchestrates neurodevelopment, synaptic function, and immune response

279 e implicated biological processes related to neurodevelopment, synaptic integrity, and neurotransmiss

280 dentified 199 genes putatively implicated in neurodevelopment, synaptic signaling, axonal transport,

281 nfection interferes with multiple aspects of neurodevelopment that contribute to the complexity of cZ

282 nflammatory response associated with altered neurodevelopment that follows murine CMV infection of th

283 sis of microglial-enriched genes involved in neurodevelopment, the microglia sensome, and inflammatio

284 d the dysregulation of pathways important in neurodevelopment, the most significant of which was syna

285 Given the critical role of IGF1 during neurodevelopment, the present study used human induced p

286 During neurodevelopment, these mechanisms are required to gener

287 how current treatments may alter adolescent neurodevelopment to allow recovery from PTSD.

288 oexposure to arsenic, manganese, and lead on neurodevelopment using an adapted Bayley Scale of Infant

289 upled plasma mass spectrometry, and assessed neurodevelopment using the Bayley Scales of Infant Devel

290 Neurodevelopment was assessed at 18 months using the Bay

291 Neurodevelopment was assessed by Bayley Scales of Infant

292 Neurodevelopment was measured using the Vineland Adaptiv

293 rther understand the role of KIAA0319 during neurodevelopment, we carried out an expression study of

294 To study the impact of storage in postnatal neurodevelopment, we examined murine models of MPS IIIA,

295 te the function of (CPE/NF-alpha1)-DeltaN in neurodevelopment, we first cloned (CPE/NF-alpha1)-DeltaN

296 rm the basis for integrative models of fetal neurodevelopment, which propose that antenatal maternal

297 gulation is critical for human embryonic and neurodevelopment, while it's dysregulation may play a ro

298 ic polymorphisms associated with early-stage neurodevelopment will help elucidate biological mechanis

299 suggests that schizophrenia is a disorder of neurodevelopment with alterations in both early and late

300 polyunsaturated fatty acid (PUFA) intake on neurodevelopment with long-lasting consequences on behav