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1 phenotypically and genetically heterogeneous neurodevelopmental disorder.
2 eterious CDK19 variants underlie a syndromic neurodevelopmental disorder.
3 velopmental syndrome, termed syt1-associated neurodevelopmental disorder.
4 in neonatal populations at increased risk of neurodevelopmental disorder.
5 ntial treatment approach for syt1-associated neurodevelopmental disorder.
6 provide clues to the pathophysiology of this neurodevelopmental disorder.
7 it has not previously been associated with a neurodevelopmental disorder.
8 ed that insufficiency of DLL1 causes a human neurodevelopmental disorder.
9 r association to Rett Syndrome (RTT), a rare neurodevelopmental disorder.
10 CDH2 has not yet been linked to a Mendelian neurodevelopmental disorder.
11 usination of eIF5A and are associated with a neurodevelopmental disorder.
12 nting, causes Angelman syndrome (AS), a rare neurodevelopmental disorder.
13 disruptions of this gene in a characteristic neurodevelopmental disorder.
14 ions for the diagnosis and treatment of this neurodevelopmental disorder.
15 critical role in the pathogenicity of human neurodevelopmental disorder.
16 disease-modifying treatment for a syndromic neurodevelopmental disorder.
17 Schizophrenia (SCZ) is a neurodevelopmental disorder.
18 s besides cancer, including lung, renal, and neurodevelopmental disorders.
19 ons toward understanding the pathogenesis of neurodevelopmental disorders.
20 including benign and malignant neoplasia and neurodevelopmental disorders.
21 g these genes in COS as well as in pediatric neurodevelopmental disorders.
22 cardiac anomalies, limb dysmorphologies and neurodevelopmental disorders.
23 PTCHD1-AS in genetic risk for ASD and other neurodevelopmental disorders.
24 synaptic pruning is associated with several neurodevelopmental disorders.
25 nvolved in proteostasis is a common cause of neurodevelopmental disorders.
26 nervous system causing neurodegeneration to neurodevelopmental disorders.
27 over-representation of left-handers in some neurodevelopmental disorders.
28 er called "transcriptome reversal" for these neurodevelopmental disorders.
29 tated in many patients with autism and other neurodevelopmental disorders.
30 nts affected genes which are associated with neurodevelopmental disorders.
31 al period, features that may be disrupted in neurodevelopmental disorders.
32 SR leads to maternal inflammation-associated neurodevelopmental disorders.
33 underlie aberrant sensory processing in some neurodevelopmental disorders.
34 periods, is hypothesized to be disrupted in neurodevelopmental disorders.
35 on of this regulatory pathway contributes to neurodevelopmental disorders.
36 represent a contributing factor in multiple neurodevelopmental disorders.
37 ine the origin of abnormal gamma activity in neurodevelopmental disorders.
38 on channel family are linked to epilepsy and neurodevelopmental disorders.
39 of de novo mutations associated with complex neurodevelopmental disorders.
40 ears of age is important in the detection of neurodevelopmental disorders.
41 or overlapped with genes identified in other neurodevelopmental disorders.
42 opicalis as a model system for understanding neurodevelopmental disorders.
43 s the mechanism underlying GABRB2-associated neurodevelopmental disorders.
44 MECP2 is involved in two severe and complex neurodevelopmental disorders.
45 ants (CNVs) have a higher risk of developing neurodevelopmental disorders.
46 ic etiologies of ASD and, more generally, of neurodevelopmental disorders.
47 be more pronounced in patients with comorbid neurodevelopmental disorders.
48 ed biphenyls (PCBs) has been associated with neurodevelopmental disorders.
49 promotes social behavior in mouse models of neurodevelopmental disorders.
50 d an association between prenatal stress and neurodevelopmental disorders.
51 vo mutations in SLC12A2 in six children with neurodevelopmental disorders.
52 cidence of a large number of psychiatric and neurodevelopmental disorders.
53 neural networks and circuit abnormalities in neurodevelopmental disorders.
54 ved in synaptic function and the etiology of neurodevelopmental disorders.
55 health related adverse events in people with neurodevelopmental disorders.
56 f mature neurons will help better understand neurodevelopmental disorders.
57 pathogenic variants in NSUN2 being linked to neurodevelopmental disorders.
58 t are known to harbor syndromic mutations in neurodevelopmental disorders.
59 rug targets for malignancies, autoimmune and neurodevelopmental disorders.
60 or schizophrenia, epilepsy, and other common neurodevelopmental disorders.
61 including autism spectrum disorder and other neurodevelopmental disorders.
62 unomodulation, irritable bowel syndrome, and neurodevelopmental disorders.
63 nd enhancers involved in NSC maintenance and neurodevelopmental disorders.
64 CBLH and DWM are often features of monogenic neurodevelopmental disorders.
65 dies in mouse models of neuropsychiatric and neurodevelopmental disorders.
66 erstanding may help us design treatments for neurodevelopmental disorders.
67 rformed exome sequencing in individuals with neurodevelopmental disorders.
68 oxidative stress as a therapeutic target in neurodevelopmental disorders.
69 eptor subunits have been found in a range of neurodevelopmental disorders.
70 uch, mutations in either protein can lead to neurodevelopmental disorders.
71 tasks, even though these are very different neurodevelopmental disorders.
72 mutations had been associated with syndromic neurodevelopmental disorders.
73 nesis whose orthologs include risk genes for neurodevelopmental disorders.
74 n social dynamics and is impaired in several neurodevelopmental disorders.
75 ield a broad range of behavioral deficits in neurodevelopmental disorders.
76 tial opportunities for precision medicine in neurodevelopmental disorders.
77 em a potential key point of vulnerability in neurodevelopmental disorders.
78 ranscriptional dysregulation in co-occurring neurodevelopmental disorders.
79 these behaviors in many neuropsychiatric and neurodevelopmental disorders.
80 ure to endocrine disruptors and incidence of neurodevelopmental disorders.
81 n histone-modifying enzymes may cause severe neurodevelopmental disorders.
82 hypofunction has been implicated in several neurodevelopmental disorders.
83 o determine the genetic aetiology underlying neurodevelopmental disorders.
84 tic capacity are known to cause a variety of neurodevelopmental disorders.
85 y-based vaccine preservative and the risk of neurodevelopmental disorders; (3) vaccine-induced Guilla
87 gnancy are associated with increased risk of neurodevelopmental disorders, although the precise mecha
88 A2 de novo mutations as the cause of a novel neurodevelopmental disorder and bilateral non-syndromic
89 confirm that persistent ADHD in adults is a neurodevelopmental disorder and extend the existing hypo
90 dysfunction in Down ayndrome (trisomy 21), a neurodevelopmental disorder and form of early onset AD,
91 ted de novo variants from 6753 patients with neurodevelopmental disorders and 1911 unaffected sibling
92 ), a pro-inflammatory cytokine implicated in neurodevelopmental disorders and gestational disease.
94 ive Pol III mutations have been described in neurodevelopmental disorders and hypersensitivity to vir
95 TOR pathway genes are linked to a variety of neurodevelopmental disorders and malformations of cortic
96 sm spectrum disorder (ASD) is a continuum of neurodevelopmental disorders and needs new therapeutic a
97 inked to synapse pathologies associated with neurodevelopmental disorders and neurodegenerative disea
98 omosomal locus are associated with syndromic neurodevelopmental disorders and reciprocal physiologica
101 hedding light on the genetic architecture of neurodevelopmental disorders, and new approaches are rev
102 bellum is a key brain region in a variety of neurodevelopmental disorders, and the adult cerebellum h
103 ose loss from the maternal allele causes the neurodevelopmental disorder Angelman syndrome (AS).
106 However, it is unclear how genetic risks for neurodevelopmental disorders are translated into spatial
109 ses understanding of the complex etiology of neurodevelopmental disorders arising from rare missense
110 nces of 101 known de novo variant-associated neurodevelopmental disorders as well as 3106 putative mo
112 e 22q11.2 deletion syndrome (22q11.2DS) is a neurodevelopmental disorder associated with a number of
113 riants in SCAF4 are causative for a variable neurodevelopmental disorder associated with impaired mRN
114 iants as the cause of a characteristic human neurodevelopmental disorder associated with mild facial
115 romatosis type 1 (NF1) is a common monogenic neurodevelopmental disorder associated with physical and
116 ne duplication in KIF21B in individuals with neurodevelopmental disorders associated with brain malfo
117 show that ankyrin-G interacts with Usp9X, a neurodevelopmental-disorder-associated deubiquitinase (D
119 the vast majority of these de novo monogenic neurodevelopmental disorders because of phenotypic heter
120 y has been implicated in the pathogenesis of neurodevelopmental disorders but its contribution to syn
122 only associated with schizophrenia and other neurodevelopmental disorders, but are also a contributin
123 co-striatal assembloids from patients with a neurodevelopmental disorder caused by a deletion on chro
131 dependent kinase-like 5 disorder is a severe neurodevelopmental disorder caused by mutations in the X
135 ortical neuroimaging data from patients with neurodevelopmental disorders caused by genomic copy numb
136 it/hyperactivity disorder (ADHD) is a common neurodevelopmental disorder characterized by age-inappro
137 2 in unrelated individuals presenting with a neurodevelopmental disorder characterized by axial hypot
139 in CDH2 in nine individuals with a syndromic neurodevelopmental disorder characterized by global deve
141 Loss-of-function SYNGAP1 mutations cause a neurodevelopmental disorder characterized by intellectua
142 ocerebrofacial syndrome (KOS) is a recessive neurodevelopmental disorder characterized by intellectua
144 ift variants in NOVA2 affected with a severe neurodevelopmental disorder characterized by intellectua
145 Affected individuals demonstrated a variable neurodevelopmental disorder characterized by mild intell
146 reminiscent of human ocular motor apraxia, a neurodevelopmental disorder characterized by reduced sac
148 s complex (TSC) is a rare autosomal dominant neurodevelopmental disorder characterized by variable ex
149 ls from six unrelated families, exhibiting a neurodevelopmental disorder characterized with a spectru
150 tual disability disorders (SSRIDDs) are rare neurodevelopmental disorders characterized by developmen
151 ne xeroderma pigmentosum (XP-G) or the fatal neurodevelopmental disorder Cockayne syndrome (XP-G/CS).
152 S signaling pathway components cause diverse neurodevelopmental disorders, collectively called RASopa
154 sus NRT for smoking cessation in people with neurodevelopmental disorders, compared to those without,
155 how that de-novo variants in GRIA2 can cause neurodevelopmental disorders, complementing evidence tha
156 ndividuals present with shared features of a neurodevelopmental disorder consisting of global develop
157 functionality, suggesting that PP2A-related neurodevelopmental disorders constitute functionally con
158 ss-of-function variants in this gene cause a neurodevelopmental disorder defined by cognitive impairm
159 of Dravet syndrome (Scn1a+/- mice)-a severe neurodevelopmental disorder defined by temperature-sensi
160 less likely to be prescribed to people with neurodevelopmental disorders despite results suggesting
162 Rett syndrome (RTT) is an X-linked dominant neurodevelopmental disorder due to pathogenic mutations
164 is in the initial indication of amblyopia, a neurodevelopmental disorder for which available treatmen
167 ng LoF or deletion DNVs in LoF-intolerant or neurodevelopmental disorder genes had significantly less
170 with adults with CP alone, those with CP and neurodevelopmental disorders had similar or higher age-s
171 genomic variants in schizophrenia and other neurodevelopmental disorders has so far not yielded ther
173 A variety of syndromic and non-syndromic neurodevelopmental disorders have been connected to alte
176 pectrum Disorder (ASD) is the most prevalent neurodevelopmental disorder in the United States and oft
180 mmation during pregnancy are associated with neurodevelopmental disorders in offspring, but little is
182 pport a neuroimmune mechanism that underlies neurodevelopmental disorders in which the production of
186 STXBP1 are among the most frequent causes of neurodevelopmental disorders including intellectual disa
187 tion factor eEF1A2, have been shown to cause neurodevelopmental disorders including often severe epil
188 twork connectivity, which has been linked to neurodevelopmental disorders, including autism spectrum
189 ion of interneurons is implicated in several neurodevelopmental disorders, including autism spectrum
192 genetic locus are associated with a range of neurodevelopmental disorders, including autism spectrum
193 ild speech and language delay to intractable neurodevelopmental disorders, including but not limited
194 gene encoding ankyrin-G are associated with neurodevelopmental disorders, including intellectual dis
195 ss are implicated in the etiology of complex neurodevelopmental disorders, including schizophrenia, a
197 r and among de novo variants associated with neurodevelopmental disorders, including schizophrenia.
198 ion areas may underlie cognitive deficits in neurodevelopmental disorders, including the 22q11.2 dele
199 xperiments are critical because a variety of neurodevelopmental disorders, including those characteri
200 ATEMENT Down syndrome (trisomy 21) (DS) is a neurodevelopmental disorder invariably leading to early-
201 enes DDX3X and DHX30 in an emerging class of neurodevelopmental disorders involving RNA helicases.
204 tudy of sexual dimorphism in psychiatric and neurodevelopmental disorders is challenging due to the c
206 at DAPLE, a non-GPCR protein linked to human neurodevelopmental disorders, is expressed specifically
207 Sensorimotor deficits are prevalent in many neurodevelopmental disorders like autism, including one
208 5, which is associated with a higher rate of neurodevelopmental disorders like microcephaly, induced
209 iatal pathway and may shed novel insights on neurodevelopmental disorders linked to the corticostriat
210 the ARF activator Efa6 in C. elegans, and by neurodevelopmental disorders linked to the mammalian kin
211 y-use critical period.SIGNIFICANCE STATEMENT Neurodevelopmental disorders manifest symptoms at specif
212 In the full dataset, genes associated with neurodevelopmental disorders (n = 159) were significantl
215 ctivity disorder (ADHD), the entire range of neurodevelopmental disorders (NDDs) has not yet been wel
217 ediated decay (NMD) has been associated with neurodevelopmental disorders (NDDs) such as autism spect
218 self during childhood, belongs to a group of neurodevelopmental disorders (NDDs) that are clinically
219 KCNB1 variants associated with DEE or other neurodevelopmental disorders (NDDs) to rapidly ascertain
220 ns of the X-chromosome gene UPF3B cause male neurodevelopmental disorders (NDDs) via largely unknown
222 arge number of genes have been implicated in neurodevelopmental disorders (NDDs), but their contribut
228 syndrome is widely regarded as an archetypal neurodevelopmental disorder of central, motor control.
229 mented and cost-effective screening tool for neurodevelopmental disorders, particularly in cases when
230 ts in OCD are enriched for those reported in neurodevelopmental disorders, particularly Tourette's di
231 set of the data from the Province of Ontario Neurodevelopmental Disorder (POND) Network was used incl
234 ylating enzyme that has been associated with neurodevelopmental disorders primarily in female subject
235 rsely, increased lactate was associated with neurodevelopmental disorders regardless of genotype (p =
238 nsight into the possible etiology underlying neurodevelopmental disorders resulting from histamine dy
239 is question and to provide a novel model for neurodevelopmental disorders resulting from mutations in
241 ions in the MECP2 gene cause the progressive neurodevelopmental disorder Rett syndrome(3-5), which is
242 eural cultures lacking MECP2, a model of the neurodevelopmental disorder Rett syndrome, with exosomes
244 or behaviour, it is not surprising that most neurodevelopmental disorders share motor deficits as a c
246 nding the neural basis of autism and related neurodevelopmental disorders.SIGNIFICANCE STATEMENT The
247 ng health issues, such as epilepsy and other neurodevelopmental disorders, sleep problems, and mental
251 uitry, and its disruption has been linked to neurodevelopmental disorders such as autism and schizoph
252 s) is linked to increased risk for offspring neurodevelopmental disorders such as autism spectrum dis
253 ious benign and malignant tumors, as well as neurodevelopmental disorders such as autism spectrum dis
254 We ask how this framework can be applied to neurodevelopmental disorders such as autism spectrum dis
256 vity is a common and debilitating feature of neurodevelopmental disorders such as Fragile X Syndrome
257 tor of chromatin topology recently linked to neurodevelopmental disorders such as intellectual disabi
258 sal ganglia disorders, including early-onset neurodevelopmental disorders such as obsessive-compulsiv
259 ynapses, and its disruption is implicated in neurodevelopmental disorders such as Phelan-McDermid syn
261 as been linked to complex disease, including neurodevelopmental disorders such as schizophrenia and a
262 the Kanizsa illusory contours is impaired in neurodevelopmental disorders such as schizophrenia, auti
264 lity in humans and have been linked to other neurodevelopmental disorders, such as autism spectrum di
265 behaviors and its dysregulation is linked to neurodevelopmental disorders, such as autism spectrum di
266 l (CBD) as a treatment for mental health and neurodevelopmental disorders, such as autism spectrum di
267 omposition and function modulate the risk of neurodevelopmental disorders, such as schizophrenia.
268 spectrum disorder (ASD) is a multifactorial neurodevelopmental disorder that encompasses a complex a
269 n-deficit/hyperactivity disorder (ADHD) is a neurodevelopmental disorder that is consistently associa
270 nia is still unknown, it is accepted to be a neurodevelopmental disorder that results from the intera
271 sessive-compulsive disorder (OCD) are common neurodevelopmental disorders that frequently co-occur.
272 ironmental insults causes a constellation of neurodevelopmental disorders that manifest as intellectu
273 ormations of cortical development (MCDs) are neurodevelopmental disorders that result from abnormal d
274 grammed microglia or their products in human neurodevelopmental disorders that share this neuropathol
275 l dysphagia-is often associated with several neurodevelopmental disorders that subsequently alter com
276 and penetrant microdeletion associated with neurodevelopmental disorders, the 22q11.2 microdeletion
277 velopment, and the role of EphB receptors in neurodevelopmental disorders, these findings establish a
280 atric comorbidities in adults with these two neurodevelopmental disorders using population-based data
281 (DNMs) are significant risk factors in many neurodevelopmental disorders, whereas schizophrenia (SCZ
282 , as its loss leads to fragile X syndrome, a neurodevelopmental disorder which is the most prevalent
283 variant burden of NCKAP1 in individuals with neurodevelopmental disorders which needs further replica
284 ities to model and test therapies for severe neurodevelopmental disorders, while revealing significan
285 rder (ADHD) is a common and highly heritable neurodevelopmental disorder with a complex pathophysiolo
286 vity disorder (ADHD) is a severely impairing neurodevelopmental disorder with a prevalence of 5% in c
289 de novo variants in MAPK8IP3 as a cause of a neurodevelopmental disorder with intellectual disability
291 it/Hyperactivity Disorder (ADHD) is a common neurodevelopmental disorder with only symptomatic care a
292 nd female Dravet syndrome (Scn1a+/-) mice, a neurodevelopmental disorder with prominent temperature-s
293 dividuals with HVDAS, adding to the group of neurodevelopmental disorders with an epigenetic signatur
294 or oligodendrocyte and myelin dysfunction in neurodevelopmental disorders with cognitive symptoms.
295 pectrum disorder (ASD) is a constellation of neurodevelopmental disorders with high phenotypic and ge
296 ging data and the male prevalence in various neurodevelopmental disorders with inhibitory dysfunction
297 rum Disorder (ASD) is one of the most common neurodevelopmental disorders with no drugs treating the
298 N2A, have been associated with a spectrum of neurodevelopmental disorders with prominent speech-relat
299 tism spectrum disorders (ASD) are a group of neurodevelopmental disorders with symptoms including soc
300 genes encoding synaptic proteins cause many neurodevelopmental disorders, with the majority affectin