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5 ion, the HFD stimulated the proliferation of neuroepithelial and neuronal precursor cells of the embr
6 nd mediolateral gene expression gradients in neuroepithelial and radial glial progenitors (the 'proto
7 ges in conducting airways, and distinguishes neuroepithelial and tracheal-bronchial gland cell lineag
8 cle arrest that underpins the specificity of neuroepithelial apoptosis and neural crest cell hypoplas
10 is; thus suggesting that it is p53-dependent neuroepithelial apoptosis that is the primary mechanism
11 some TiPSC-OVs maintained their distinctive neuroepithelial appearance and spontaneously formed prim
13 elial cells, promotes the enlargement of the neuroepithelial basal end-foot and traps Hh protein, the
14 that is required for its localization to the neuroepithelial basement membrane (BM) to effectively an
15 opore closure, accompanied by suppression of neuroepithelial bending at the median hinge point and ac
16 cretory precursors juxtaposed to presumptive neuroepithelial bodies (NEBs), distinguished by their st
18 esulted in considerable depletion of CGRP in neuroepithelial bodies and submucosal nerve plexuses wit
19 these mice manifested an increased number of neuroepithelial bodies but a reduced number of solitary
22 submucosal glands/intercartilagenous rings, neuroepithelial bodies, and terminal bronchioles/broncho
23 ly proposed airway chemosensory element, the neuroepithelial body (and its immortalized cellular coun
24 )-expressing stem cells that localize to the neuroepithelial body (NEB) and contribute to renewal of
25 other cancer cell lines including breast and neuroepithelial cancer, melanoma, and leukemia cell line
29 kinase activity is essential for regulating neuroepithelial cell adhesion, migration and morphogenes
30 ic reticulum stress, caspase activation, and neuroepithelial cell apoptosis (causal events in type 1
31 (K1361R) embryos show a striking increase in neuroepithelial cell apoptosis and a dramatic loss of ph
32 predominantly leads to exencephaly, induces neuroepithelial cell apoptosis and suppresses autophagy
38 event(s) involved in the maintenance of the neuroepithelial cell layer shortly after its formation.
39 erebral cortical precursor cells reside in a neuroepithelial cell layer that regulates their prolifer
41 autonomously within the retina and brain, as neuroepithelial cell morphology and polarity in these ti
42 as key regulatory elements in the control of neuroepithelial cell proliferation and the neuroblast tr
44 helial stem cell phenotype and regulation of neuroepithelial cell proliferation, suggesting that a mu
45 3, MAD2, CDC28 protein kinase (CKS)1 and 2, neuroepithelial cell transforming gene (NET)1, activator
47 athological angiogenesis caused by defective neuroepithelial cell-endothelial cell adhesion and imbal
48 basal progenitors (BPs), differentiate from neuroepithelial cells (NCs) with stem cell properties.
51 racellular calcium concentration of isolated neuroepithelial cells (NECs), which are putative oxygen
53 at mediate the transition, we microdissected neuroepithelial cells and compared their transcriptional
54 of activated Yorkie, promotes overgrowth of neuroepithelial cells and delays or blocks their differe
55 rt to a molecular state resembling embryonic neuroepithelial cells and functionally acquire rapid pro
57 g of postmitotic neurons is mediated through neuroepithelial cells and is necessary for guiding neuro
58 ver, Cited2 was required for the survival of neuroepithelial cells and its absence led to massive apo
59 developing mouse cortex where the expansive neuroepithelial cells and neurogenic radial glial progen
60 e/Afadin, mislocalize in dividing Eph mutant neuroepithelial cells and produce spindle alignment defe
61 tion, DAPLE localizes to apical junctions of neuroepithelial cells and promotes apical cell constrict
63 ment, CPECs differentiate from preneurogenic neuroepithelial cells and require bone morphogenetic pro
65 s and is required for apical constriction of neuroepithelial cells and subsequent neural plate bendin
66 migration differentially positions nuclei in neuroepithelial cells and therefore influences selection
67 iating adhesion and signaling events between neuroepithelial cells and vascular endothelial cells.
68 to be expressed along the apical surfaces of neuroepithelial cells and was coexpressed with Shh in th
69 n contrast, proliferation of MEKK4-deficient neuroepithelial cells appeared to be largely unaffected.
70 trations ([Ca2+]i) in proliferating cortical neuroepithelial cells are markedly dependent on Ca2+ ent
73 ches, we show that dystroglycan functions in neuroepithelial cells as an extracellular scaffold to ma
75 These results suggest that the remaining neuroepithelial cells at later stages of animal life are
78 is localized to apical adhesive junctions of neuroepithelial cells during neurulation and that Xena k
80 ex, sequential transcriptional programs take neuroepithelial cells from proliferating progenitors to
81 rreversible retraction of the endfeet of the neuroepithelial cells from the vitreal surface of the re
84 ion strategy involves symmetrically dividing neuroepithelial cells generating large numbers of asymme
88 not support the commonly held view that most neuroepithelial cells in the embryonic CNS VZ are stem c
90 g stem cells, which comprise the majority of neuroepithelial cells in the ventricular zone (VZ) of th
91 Here, we report that apicobasally polarized neuroepithelial cells in Xenopus laevis have a shorter c
93 opment, from a seemingly homogenous sheet of neuroepithelial cells into a complex structure that is t
95 l expansion of the Olig1/Olig2 expression in neuroepithelial cells into the Nkx2.2 domain and a conse
97 ural tube, and forced expression of Foxj1 in neuroepithelial cells is sufficient to increase cilia le
99 urons, like projection neurons, develop from neuroepithelial cells located near the ventricular layer
100 ound in cobblestone lissencephalies in which neuroepithelial cells migrate into superficial layers of
101 port that the knockdown of Htt expression in neuroepithelial cells of neocortex results in disturbed
102 determined that NDE1 is highly expressed in neuroepithelial cells of the developing cerebral cortex,
103 t is a major challenge to understand how the neuroepithelial cells of the developing CNS choose betwe
104 l, human PSCs are first induced to primitive neuroepithelial cells over 10 d, and then patterned to N
106 NA and protein was specifically expressed in neuroepithelial cells surrounding retinal axons at the o
107 lian taste buds are comprised of specialized neuroepithelial cells that act as sensors for molecules
108 aste buds are aggregates of 50-100 polarized neuroepithelial cells that detect nutrients and other co
109 c spindle alignment in Drosophila optic lobe neuroepithelial cells through aPKC activity-dependent my
112 ur studies establish that the progression of neuroepithelial cells to neuroblasts is regulated by Not
114 l stem cells (NSCs) undergo transitions from neuroepithelial cells to radial glial cells (RGCs), and
115 ion is highly reminiscent of the switch from neuroepithelial cells to radial glial cells in the devel
116 at Notch signalling augments the response of neuroepithelial cells to Shh, leading to the induction o
117 or Cx43 in which Cx43 acts through non-crest neuroepithelial cells to suppress cellular delamination
118 olecular biology techniques in both cultured neuroepithelial cells treated with a GCN5 inhibitor and
121 man stem cells are first differentiated into neuroepithelial cells with or without exogenous patterni
122 ivo, yet because RGCs develop from polarized neuroepithelial cells within a polarized environment, di
123 al crest-derived, and the hypoxia-sensitive 'neuroepithelial cells' (NECs) of fish gills, whose embry
124 central nervous system (CNS) is regulated by neuroepithelial cells, although the genes and pathways t
125 romotes proliferation and differentiation of neuroepithelial cells, and identify Decorin as a novel n
126 ave transiently suppresses Notch activity in neuroepithelial cells, and that inhibition of Notch trig
127 ulation, which underlies constriction of the neuroepithelial cells, and that ultimately drive neural
128 al expression of specific metabolic genes in neuroepithelial cells, but not in neuroblasts, and highl
129 he surrounding brain parenchyma, composed of neuroepithelial cells, glia, and neuronal precursors.
130 inantly localizes to the basolateral side of neuroepithelial cells, promotes the enlargement of the n
131 niche is composed of a diverse repertoire of neuroepithelial cells, radial glia (RG), and intermediat
132 serve nuclear movements in zebrafish retinal neuroepithelial cells, we show that, except for brief ap
135 eks, hESCs are induced to differentiate into neuroepithelial cells, which form neural tube-like roset
136 The Drosophila optic lobe develops from neuroepithelial cells, which function as symmetrically d
158 resent in the developing neural tube (E10.5, neuroepithelial cells; NEP) were examined for the expres
159 cells acquire apicobasal polarity and adopt neuroepithelial character prior to other regions of the
160 d early depletion of adenylyl cyclase III in neuroepithelial cilia, implicating deficient pathway rep
164 Treatment of dissociated mouse cortical neuroepithelial cluster cell cultures with the NO syntha
166 rchestrates the differential growth of optic neuroepithelial compartments during vertebrate eye devel
169 the lumen of the nasal cavity than are their neuroepithelial counterparts, therefore having quicker a
171 of the ECM in the development of complex 3D neuroepithelial cysts that recapitulate key steps in ear
175 se cortical progenitors, we found that early neuroepithelial deletion of ciliary Arl13b led to a reve
176 growth factor A (VEGF) isoforms during early neuroepithelial development in the mammalian central ner
179 pothesized that hypomethylation of Pax3 upon neuroepithelial differentiation may be inhibited by hype
180 egulators, including E2f1 and CyclinD, delay neuroepithelial differentiation, and Fat-Hippo signaling
181 ctrum of neural tube defects associated with neuroepithelial disorganization and enhanced progenitor
182 ns intrathalamica (ZLI), a transverse linear neuroepithelial domain in the alar plate of the dienceph
183 genetic manipulations, we found that one IPC neuroepithelial domain progressively transformed into mi
184 scription factor MITF plays central roles in neuroepithelial domain specification and differentiation
186 sic fibroblast growth factor), activated the neuroepithelial enhancer of the nestin gene, and gave ri
189 xpression of Tbeta4 led to the production of neuroepithelial folds resembling gyri and sulci, which a
190 s characterization of Fat-Hippo signaling in neuroepithelial growth and differentiation also provides
191 d pressure during development, we found that neuroepithelial growth depends on not only chemical morp
192 d in the progression of stem cells along the neuroepithelial-->radial glia-->astrocyte lineage.
193 permanent hearing loss through apoptosis of neuroepithelial hair cells and afferent neurons of the c
194 ce ectoderm shows a shift from epithelial to neuroepithelial identity (with ectopic expression of N-c
201 ed in restricted dorsoventral domains of the neuroepithelial layer at early developmental stages (E2.
204 e produced during the larval period from two neuroepithelial layers called the outer and inner optic
205 mode of axogenesis and dendritogenesis from neuroepithelial-like processes may act to preserve neigh
206 mark for the production of similar long-term neuroepithelial-like stem cells (lt-NES) from pluripoten
207 bouton (B) afferents distinguished by their neuroepithelial locations into BT units near the torus a
208 m cell markers Thy-1, c-kit, and CD34 or the neuroepithelial marker neural cell adhesion molecule 1.
209 r glia partially dedifferentiate, re-express neuroepithelial markers and re-enter the cell cycle.
210 ent with ethanol induction of cell cycle and neuroepithelial maturation in the absence of apoptosis.
211 onal knockout of the small GTPase Cdc42 from neuroepithelial (NE) and radial glial (RG) cells in the
212 re we find that cell cycle dynamics of human neuroepithelial (NE) cells differ from radial glial (RG)
213 Pluripotent stem cells are induced to form neuroepithelial (NE) cells that form neural tube-like ro
214 igoneuronal precursors, neuronal precursors, neuroepithelial/neural crest precursors, or astrocyte pr
218 of NSCs, a property tightly linked to their neuroepithelial origin, appear to be the key determinant
220 l that alphaE-catenin is highly expressed in neuroepithelial precursor cells in the developing cortic
221 have enlarged lateral ventricles lined with neuroepithelial precursor cells, reflecting an expansion
224 nic subcortical telencephalon where distinct neuroepithelial precursors generate defined interneuron
225 ll subset of OPCs arise from common olig2(+) neuroepithelial precursors in rhombomeres r5 and r6, but
226 de that (1) Fgfr3 marks astrocytes and their neuroepithelial precursors in the developing CNS and (2)
227 (mTERT) prevented telomere collapse and the neuroepithelial precursors produced continued to divide,
229 ormal neuronal differentiation, with loss of neuroepithelial progenitor cell phenotype in the subvent
231 n at early developmental stages when retinal neuroepithelial progenitor cells predominate, we sought
232 are the only glial cell type produced by the neuroepithelial progenitor cells that generate the verte
234 addition at the pallial edge from a discrete neuroepithelial progenitor pool of the posterior telence
235 e and cell-cell interactions of radial glial neuroepithelial progenitors by the Lis1-Nde1 complex is
236 nascent cell-cell adhesion clusters between neuroepithelial progenitors contribute to define orienta
237 ons differentiated, more dorsally positioned neuroepithelial progenitors descended to the pMN domain
239 r heighten the potential for using olfactory neuroepithelial progenitors for future autologous cell r
241 are positioned within the apical membrane of neuroepithelial progenitors, we hypothesized that loss o
245 factor receptor (EGFR) activation to promote neuroepithelial proliferation and neuroblast formation.
249 loss of Lgl1 in mice results in formation of neuroepithelial rosette-like structures, similar to the
252 n alleles affect the polarity of the retinal neuroepithelial sheet and, unexpectedly, both result in
253 c failure of hingepoint formation, defective neuroepithelial sheet-bending, and failure of neural tub
255 xpression in primary human hindbrain-derived neuroepithelial stem (hbNES) cells or iPSC-derived NES c
256 ed pluripotent stem (iPS) cell-derived human neuroepithelial stem (NES) cells generated from a Gorlin
259 cal role for elf in the development of a SVZ neuroepithelial stem cell phenotype and regulation of ne
260 control of symmetric division, essential for neuroepithelial stem cell proliferation, is mediated thr
262 conducted gene expression profiling of human neuroepithelial stem cell-derived neurons, stimulated wi
263 , suggesting a sequential differentiation of neuroepithelial stem cells (NEPs) to GRPs to ARPs and th
264 bryonic spinal cord, for example, a group of neuroepithelial stem cells (NSCs) generates motor neuron
265 ntrol of mitotic spindle orientation in both neuroepithelial stem cells and radial glial progenitor c
266 odermal domain that combines slowly dividing neuroepithelial stem cells and rapidly amplifying progen
267 lia of the mouse cerebral cortex emerge from neuroepithelial stem cells around embryonic day 11 and p
270 the first demonstration of highly expandable neuroepithelial stem cells derived from the human embryo
273 ctory loss, caused by a functional switch of neuroepithelial stem cells from regeneration to immune d
275 est that, during nervous system development, neuroepithelial stem cells may not only be responsible f
276 deletion and severe apoptosis of the founder neuroepithelial stem cells, accompanied by increased hor
277 sors are sequentially generated in vivo from neuroepithelial stem cells, but do not share a common li
278 t of generation of GRP cells from totipotent neuroepithelial stem cells, of O2A/OPCs from GRP cells a
279 in a cell lineage-specific manner, mainly in neuroepithelial stem cells, radial glia, and astrocytes.
280 Controlled gene deletion of Lis1 in vivo in neuroepithelial stem cells, where cleavage is uniformly
282 demonstrate that RhoA functions to maintain neuroepithelial structures in the developing spinal cord
283 mitotic populations that were present in the neuroepithelial subventricular zone of the developing ne
285 s in each of these structures in the tongue, neuroepithelial taste cells of the taste bud, and, possi
286 Our data suggest that epithelial cells, neuroepithelial taste cells, or olfactory sensory neuron
287 osensory machinery discovered in specialized neuroepithelial taste receptor cells of the lingual epit
289 ary identify Fgf10 as a key regulator of the neuroepithelial to radial glial transition and subsequen
293 ration (CNS HGNET-MN1)," and "CNS high-grade neuroepithelial tumor with BCOR alteration (CNS HGNET-BC
294 C alteration (CNS EFT-CIC)," "CNS high-grade neuroepithelial tumor with MN1 alteration (CNS HGNET-MN1
296 of the motor cortex in patients with primary neuroepithelial tumors of the central nervous system (CN
298 e diagnoses of low-grade epilepsy associated neuroepithelial tumour (LEAT), vascular malformation, an
299 y from three common causes, dysembryoplastic neuroepithelial tumours (DNTs; eight cases), focal corti