ライフサイエンスコーパス: neuroepithelium

1 le aligned perpendicular to the plane of the neuroepithelium).

2 ogenic sprouts originated and penetrated the neuroepithelium.

3 enes and localize to specific regions of the neuroepithelium.

4 he detachment of its apical process from the neuroepithelium.

5 are making use of the developing fly retinal neuroepithelium.

6 , they detach from the apical surface of the neuroepithelium.

7 the neural crest, which is derived from the neuroepithelium.

8 nds also on the distribution of fluid in the neuroepithelium.

9 t E9.5, the primitive stem cell stage of the neuroepithelium.

10 anchiopods, and that they also remain in the neuroepithelium.

11 he crb genes in epithelia, including retinal neuroepithelium.

12 in the maintenance of the neuroblasts in the neuroepithelium.

13 the neural precursor population of the early neuroepithelium.

14 roperties before their delamination from the neuroepithelium.

15 cial ectoderm and the adjacent telencephalic neuroepithelium.

16 distinguish these cells from the rest of the neuroepithelium.

17 during initial delamination of NCCs from the neuroepithelium.

18 by a striking reorganization of the sensory neuroepithelium.

19 ue to impaired stretching of the surrounding neuroepithelium.

20 s, radially oriented, and spanned the entire neuroepithelium.

21 of neural crest cells (NCCs) and the cranial neuroepithelium.

22 nsion depend on the contractile state of the neuroepithelium.

23 but its foundation is laid in the primitive neuroepithelium.

24 allow neural crest cells to escape from the neuroepithelium.

25 progenitor production and elongation of the neuroepithelium.

26 1 confined to the apical side of the retinal neuroepithelium.

27 rvation is relatively uniform throughout the neuroepithelium.

28 law to mathematically describe growth of the neuroepithelium.

29 ay, enhancing cell proliferation within this neuroepithelium.

30 ng progenitors are found medially within the neuroepithelium.

31 onasal retina, through the remaining retinal neuroepithelium.

32 ate and their progeny fully reconstitute the neuroepithelium.

33 l proliferation in the Drosophila optic lobe neuroepithelium.

34 stnatal volumetric growth in the vomeronasal neuroepithelium.

35 of sensory epithelia from the primitive otic neuroepithelium.

36 ished as daughter cells reintegrate into the neuroepithelium.

37 than via peripheral nerves or the olfactory neuroepithelium.

38 KK4) is strongly expressed in the developing neuroepithelium.

39 o structures develop from the same embryonic neuroepithelium.

40 al transition (EMT), and delaminate from the neuroepithelium.

41 ressed in the developing otic capsule and/or neuroepithelium.

42 he nervous system, and to a repellent in the neuroepithelium.

43 ical progenitors in the dorsal telencephalic neuroepithelium.

44 gulating Olig gene expression in the ventral neuroepithelium.

45 ately responsible for regenerating olfactory neuroepithelium.

46 originate from the ventral, but not dorsal, neuroepithelium.

47 of differentiated neurons from a homogeneous neuroepithelium.

48 but exhibits an enlarged lumen and abnormal neuroepithelium.

49 adjacent non-overlapping domains of ventral neuroepithelium.

50 ied developmental defects in the ventricular neuroepithelium.

51 provide structural support for the auditory neuroepithelium.

52 ssues, including heart muscle, epidermis and neuroepithelium.

53 egation of the neural crest lineage from the neuroepithelium.

54 ing a role in neural patterning in the optic neuroepithelium.

55 to receptor proteins provided by the retinal neuroepithelium.

56 n of +Rho-mediated actin assembly within the neuroepithelium.

57 glia are widespread components of the early neuroepithelium.

58 es, the trachea, the ureter, the gut and the neuroepithelium.

59 dulated by diabetes in the murine developing neuroepithelium.

60 VCAM-1 in the mucosal tip compared with the neuroepithelium.

61 ediated cell segregation occurs in the early neuroepithelium.

62 cells and afferent processes in the sensory neuroepithelium.

63 s, are required for maintenance of the adult neuroepithelium.

64 soderm cells, as well as cells from adjacent neuroepithelium.

65 pronounced apical-basal contractions of the neuroepithelium.

66 for planar spindle orientation in the chick neuroepithelium.

67 he germinative zone of the earliest cortical neuroepithelium.

68 the FBM neurons and extrinsically within the neuroepithelium.

69 ral and targeted predominantly the olfactory neuroepithelium.

70 gesting that glia cells communicate with the neuroepithelium.

71 tachment of differentiating neurons from the neuroepithelium.

72 termined by its boundaries with the adjacent neuroepithelium.

73 dherens junctions and disorganization of the neuroepithelium.

74 identity, during differentiation of hESCs to neuroepithelium, a neuroectoderm-specific subset of pois

75 chment and generation of motility within the neuroepithelium, a process that has been poorly understo

76 indles oriented parallel to the plane of the neuroepithelium, a substantial minority divides with the

77 Here we show that the repair of neuroepithelium after lesioning is accompanied by an acu

78 A tight junction component thought absent in neuroepithelium after neural tube closure, OCLN isoform-

79 We focused attention to the human olfactory neuroepithelium, an extracranial site supplying input to

80 ackscatter microscopy to label the forebrain neuroepithelium and a modified retroviral lineage librar

81 s, apoptosis and delayed neurogenesis in the neuroepithelium and ameliorated neural tube defects.

82 progenitor cells derived from human cortical neuroepithelium and assessed its effects on the cellular

83 ural crest cells that emerge from the dorsal neuroepithelium and coalesce into segmental streams that

84 maintenance of Shh expression in the ventral neuroepithelium and differences in dorsal tissue respons

85 unication between two developing organs, the neuroepithelium and embryonic blood vessels.

86 rate asymmetric cell division and vertebrate neuroepithelium and epithelial progenitor differentiatio

87 Erm, Pea3, and Er81 in the rostral cortical neuroepithelium and FC regionalization.

88 domyoblasts effaced all but trace amounts of neuroepithelium and generated a distant metastasis entir

89 ignaling in an autocrine manner in the optic neuroepithelium and in a paracrine manner in the lens ec

90 during the development of the telencephalic neuroepithelium and in glioblastoma brain tumor cells.

91 ) is expressed in the mid-dorsal optic tract neuroepithelium and in the axons of developing retinal g

92 vicinity of junctional complexes in retinal neuroepithelium and in the photoreceptor cell layer.

93 enous tissue repair by a highly regenerative neuroepithelium and introduce a system to study the mech

94 Pax3, a gene that is expressed in embryonic neuroepithelium and is required for neural tube closure.

95 ulations in the chick to demonstrate that r3 neuroepithelium and its overlying surface ectoderm indep

96 ior to optic cup formation in both the optic neuroepithelium and lens ectoderm.

97 Placodes form in both the optic neuroepithelium and lens ectoderm.

98 mily, alpha10 (CHRNA10), from both inner-ear neuroepithelium and lymphoid tissue.

99 initially arise in restricted regions of the neuroepithelium and migrate relatively long distances to

100 at disrupts both convergent extension in the neuroepithelium and PCP in the cochlea does not disrupt

101 rtical basement membrane located between the neuroepithelium and pia-meninges.

102 vous system, whereas glia originate from the neuroepithelium and provide the scavenger population of

103 ) embryos is predominantly restricted to the neuroepithelium and remains prominent in neural progenit

104 between apical and basal neurons of the VNO neuroepithelium and rostral versus caudal AOB glomeruli,

105 ion, with major defects in the heart muscle, neuroepithelium and skin epithelium, all of which posses

106 ith antioxidants minimizes cell death in the neuroepithelium and substantially ameliorates or prevent

107 lly restricted to the central nervous system neuroepithelium and temporally controlled with doxycycli

108 Lmx1b, selectively expressed in the midline neuroepithelium and the mesenchyme respectively, causes

109 d Bmps are maintained by factors in both the neuroepithelium and the overlying mesenchyme.

110 tion that forms at the interface between the neuroepithelium and the prospective epidermis of a devel

111 ural fold tips, at the interface between the neuroepithelium and the surface ectoderm, are required f

112 MGE promotes time-dependent survival of this neuroepithelium and the time-dependent specification of

113 neural crest cells are segregated within the neuroepithelium and then delaminate from the neural tube

114 at Notch mutant clones are extruded from the neuroepithelium and undergo premature neurogenesis.

115 The cyclase was cloned from the neuroepithelium and was found to be identical in structu

116 e most caudomedial edge of the telencephalic neuroepithelium) and found that these mice faithfully re

117 re-intercalation of daughter cells into the neuroepithelium, and results in ectopic neural progenito

118 able neural identity throughout the emerging neuroepithelium, and that dysregulation of this process

119 oglial cells were visualized penetrating the neuroepithelium; and 3) CX3CR1 and CCR2 distinguished in

120 prechordal (rostral) and epichordal (caudal) neuroepithelium, anteroposterior encroachment of alar lu

121 Cell fates in the optic neuroepithelium are determined by the combinational acti

122 Midline cells in the mouse midbrain neuroepithelium are flat with large apical surfaces, whe

123 defects that originate exclusively from the neuroepithelium as a result of the simultaneous loss of

124 BLBP is expressed in the rat neuroepithelium as early as E12.5 when there is little o

125 otes Wnt8c expression, which persists in the neuroepithelium as FGF signalling declines.

126 y placode/epidermal ectoderm, and underlying neuroepithelium, as well as the emerging mandibular and

127 it reduced cell proliferation in the rostral neuroepithelium at 10 somites, followed by increased cel

128 sent in well outlined regions of the ventral neuroepithelium at 5 GW, several weeks before oligodendr

129 tructures of the amygdala originate from the neuroepithelium at both sides of the pallial-subpallial

130 is expressed ubiquitously in the ventricular neuroepithelium at embryonic day 10.5 (E10.5) but displa

131 that Hopx(+) precursors in the mouse dentate neuroepithelium at embryonic day 11.5 give rise to proli

132 retina, Ush2a mRNA expression appears in the neuroepithelium at embryonic day 17.

133 lay short and stubby cilia on the developing neuroepithelium at embryonic day 9.5 (E9.5).

134 eduction in MKK4 activity in MEKK4-deficient neuroepithelium at sites of neural tube closure.

135 oliferating neuronal progenitor cells of the neuroepithelium, becomes down-regulated during neuronal

136 vergent extension in both axial mesoderm and neuroepithelium, before the onset of neurulation.

137 und that these inductions are limited to the neuroepithelium between the ZLI and the forebrain-midbra

138 The rhombic lip is a discrete strip of neuroepithelium bordering the roofplate of the fourth ve

139 y delete Lhx2 in posteroventral hypothalamic neuroepithelium, both embryonically and postnatally.

140 lusters of cells (proneural clusters) in the neuroepithelium but expression becomes restricted to the

141 ral ganglionic eminence and frontal cortical neuroepithelium but not medial or caudal ganglionic emin

142 nuous stripe of cells that sweeps across the neuroepithelium, but the dynamics at cell and tissue lev

143 nin protein forms a honeycomb pattern in the neuroepithelium by labeling the cell periphery in a typi

144 euron progenitor (pMN) domain of the ventral neuroepithelium by the ventral midline signal Sonic hedg

145 bly shortened body axis, convoluted anterior neuroepithelium, caudal dysgenesis, and failure of chori

146 ound that the expansion coefficients of both neuroepithelium cells and radial glial progenitors follo

147 ural progenitor cells derived from olfactory neuroepithelium (CNON cells) as a genetically unaltered

148 of neurons that are highly dispersed in the neuroepithelium, consistently coexpress either G alpha(i

149 The olfactory neuroepithelium contained a Ca(2+) binding protein, neur

150 tion of EGFR signalling in clones within the neuroepithelium demonstrates that a transition wave can

151 ly proliferative cells even in the primitive neuroepithelium, demonstrating heterogeneity in cell pot

152 ural tube, a markedly increased abundance of neuroepithelium-derived cells outside of the neural tube

153 lacking itgbeta8 from cells derived from the neuroepithelium did not show signs of hemorrhage.

154 ression begins at the time that cells in the neuroepithelium differentiate into neuroblasts.

155 pathway in nasal mucosae-respiratory tracts-neuroepithelium environment in the protection against mi

156 subsequently also found in the rat olfactory neuroepithelium, especially at the apical junctional bel

157 invasion and migration of blood vessels into neuroepithelium, establishment of BBB properties, and ex

158 epithelium are capable of reconstituting the neuroepithelium even after severe damage.

159 Restoring SIRT2 expression in the developing neuroepithelium exerted identical effects as those of PD

160 The ventricular neuroepithelium exhibited focalized increase of cell pro

161 ogenitor cells dissociated from rat cortical neuroepithelium express muscarinic acetylcholine recepto

162 Adult zebrafish retinal neuroepithelium expresses three crb genes (crb1, crb2a,

163 SCN is derived from a distinct region of the neuroepithelium expressing a combination of developmenta

164 Radial glial progenitors span the neuroepithelium, extending long basal processes to form

165 tion of hair cells into rows during cochlear neuroepithelium extension.

166 nesis, OAZ is highly expressed at the dorsal neuroepithelium flanking the roof plate.

167 As the neuroepithelium folds during corticostriatal sulcus form

168 l is retracted cleanly from the lumen of the neuroepithelium, followed by movement of the cell body o

169 Failure of this migration during neuroepithelium formation leads to ectopic determination

170 ei are scattered continuously throughout the neuroepithelium, from anteroventral to posteromedial.

171 x gene Lhx2, which is expressed in the optic neuroepithelium, fulfils such a role.

172 In the olfactory neuroepithelium, globose basal cells (GBCs) are consider

173 Newborn mice lacking itgbeta8 from the neuroepithelium had hemorrhages in the cortex, ganglioni

174 diversity develops from an initially uniform neuroepithelium has been the subject of decades of semin

175 Targeted deletion of itgbeta8 from the neuroepithelium, however, resulted in bilateral hemorrha

176 The rhombic lip (RL) is the neuroepithelium immediately adjacent to the roof plate o

177 al abnormalities associated with the retinal neuroepithelium in albino mice, is consistent with other

178 Analyses of the neuroepithelium in MEKK4-deficient embryos showed massiv

179 between the apical and basal surfaces of the neuroepithelium in phase with their cell cycle, a proces

180 yolk sac and in periventricular cells of the neuroepithelium in the brain.

181 junctions and causes disorganization of the neuroepithelium in the developing nervous system.

182 opment revealed that the anterior cerebellar neuroepithelium in the early embryonic cerebellum was ex

183 e initially expressed in distinct domains of neuroepithelium in young embryos.

184 ot disrupt Dvl2 membrane distribution in the neuroepithelium, in contrast to its drastic effect on Dv

185 previously unrecognized role for mesenchyme-neuroepithelium interactions in the mid-hindbrain during

186 ment of the cerebral cortex from a primitive neuroepithelium into a complex laminar structure underly

187 Differentiation of the pluripotent neuroepithelium into neurons and glia is accomplished by

188 ing nervous system: subdivision of the early neuroepithelium into precursors with distinct molecular

189 Transplantation of BrdU-labeled MGE or LGE neuroepithelium into the basal telencephalon of unlabele

190 demonstrate that bipotentiality of the optic neuroepithelium is associated with the initial coexpress

191 Expression of Nkx6.1 in the remaining neuroepithelium is closely associated with, and regulate

192 the mid-hindbrain boundary (MHB) within the neuroepithelium is dependent on the interface of Otx2 an

193 Deficiency of apical retinal neuroepithelium is indicated by altered localization of

194 Cilia outgrowth in cells of the neuroepithelium is initiated but the axonemes are severe

195 ural progenitors in the developing mammalian neuroepithelium is marked by cadherin-based adherens jun

196 nal cord and that proper organization of the neuroepithelium is required for appropriate left-right m

197 Detachment of newborn neurons from the neuroepithelium is required for correct neuronal archite

198 ve capacity, the function of human olfactory neuroepithelium is significantly impaired in chronic inf

199 Since the contractile state of the neuroepithelium is tightly regulated by non-muscle myosi

200 Limbal epithelium, which, like the neuroepithelium, is ectodermally derived, participates i

201 lso develops a progressive denudation of the neuroepithelium, leading to periventricular nodule forma

202 Fate-mapping analysis after olfactory neuroepithelium lesioning shows that HBCs are competent

203 agenesis, replacement of the ventral RPE by neuroepithelium-like tissue, and ectopic expression of o

204 ate both neuronal and non-neuronal olfactory neuroepithelium lineages.

205 , is essentially a small island of olfactory neuroepithelium located bilaterally at the ventral base

206 examine their distinct dynamics in olfactory neuroepithelium maintenance and regeneration.

207 During brain morphogenesis, the neuroepithelium must fold in specific regions to delinea

208 escence and the distribution of fluid in the neuroepithelium, namely subretinal fluid or posterior re

209 The telencephalic neuroepithelium (NE) of mammalian brain has an apical-ba

210 sal cells (HBCs) function as adult olfactory neuroepithelium neural stem cells and examine their dist

211 These data from the olfactory neuroepithelium niche provide evidence that neuron produ

212 established from cultures of adult olfactory neuroepithelium obtained from patients and cadavers as d

213 We evaluated the olfactory neuroepithelium (OE) and brain regional responses to a n

214 C5aR was also found to be expressed in the neuroepithelium of early human embryos.

215 cted directly into the saccular or utricular neuroepithelium of fascicularis (Macaca fascicularis) or

216 In the neuroepithelium of neurulating embryos, Dvl2 shows DEP d

217 , and the elevated apoptosis observed in the neuroepithelium of the Cited2(-/-) mutants was apparentl

218 Sox2 is expressed highly in the neuroepithelium of the developing CNS and has been shown

219 Wnt7b encode two Wnt ligands produced by the neuroepithelium of the developing CNS coincident with va

220 he generation of neural crest cells from the neuroepithelium of the dorsal neural tube.

221 Radial glial cells (RGCs) in the ventricular neuroepithelium of the dorsal telencephalon are the prog

222 n and migration are crucial to transform the neuroepithelium of the embryonic forebrain into the adul

223 Upon morphogenesis, the simple neuroepithelium of the optic vesicle gives rise to four

224 mbryonic surface ectoderm and the underlying neuroepithelium of the optic vesicle.

225 The vertebrate eye develops from the neuroepithelium of the ventral forebrain by the evaginat

226 which has three major components: olfactory neuroepithelium, olfactory bulb, and olfactory cortex.

227 e 1 (LTh-1) redirected TT into the olfactory neuroepithelium (ON/E).

228 In contrast, olfactory neuroepithelium (ONe) located in the nasal passageways h

229 rchitectures such as a multilayered cortical neuroepithelium or an entire optic cup.

230 cursors as a cell culture model of embryonic neuroepithelium or neural crest.

231 o BLM activity was detected in the olfactory neuroepithelium or OSNs.

232 e not significantly altered in the embryonic neuroepithelium or within the postnatal subventricular z

233 letal regulators Rac1 or Cdc42 in the dorsal neuroepithelium, or in the surface ectoderm, we show tha

234 fy the developmental competence of the optic neuroepithelium over time and thereby provide a mechanis

235 o the apical region of the retinal and brain neuroepithelium, partially overlapping the adherens junc

236 Loss of RelA in the regenerating neuroepithelium perturbs the homeostasis between prolife

237 urogenic niches can be viewed as "displaced" neuroepithelium, pockets of cells and local signals that

238 beta8 integrin in the neuroepithelium promotes the activation of extracellular

239 ns of the midbrain and hindbrain ventricular neuroepithelium, raising the possibility that Foxa2 acti

240 ation assays we show that RA activity in the neuroepithelium regulates hindbrain patterning directly

241 ion or the maintenance of neuroblasts in the neuroepithelium represents the ancestral state.

242 results suggest that: (1) the optic vesicle neuroepithelium requires a temporally specific associati

243 of Ilk from embryonic mouse dorsal forebrain neuroepithelium results in severe cortical lamination de

244 FPC function in RGC axons or the optic tract neuroepithelium results in unexpectedly localized pathfi

245 ithelium, and less intense expression in the neuroepithelium, retina, and hindgut.

246 and Fgf17 signaling on the rostral cortical neuroepithelium, revealed by altered expression of Spry1

247 the development of the hemispherical retinal neuroepithelium (RNE), a part of the optic cup.

248 s stem and progenitor cells that support the neuroepithelium's life-long capacity to reconstitute aft

249 gate into the embryo but remain in the outer neuroepithelium, similar to vertebrate neural stem cells

250 n to identify genes enriched in the germinal neuroepithelium, so as to distinguish those expressed in

251 he CNS, with concurrent sparing of olfactory neuroepithelium, strongly suggests that invasion of the

252 glia that extend processes that ensheath the neuroepithelium, suggesting that glia cells communicate

253 e notochord, and diminished in the overlying neuroepithelium, suggesting that sonic hedgehog signalli

254 defects in apical/basal polarity within the neuroepithelium, suggesting that the cfy gene is not cri

255 ear within a region of anterior hypothalamic neuroepithelium that co-expresses mRNA encoding SHH, its

256 expression in the distal tips of the retinal neuroepithelium that form the iris and ciliary body, thu

257 activity of secondary organizers within the neuroepithelium that function by releasing diffusible si

258 over time to produce different neurons; the neuroepithelium that generates neuroblasts is also subdi

259 ombic lip (RL) is an embryonic proliferative neuroepithelium that generates several groups of hindbra

260 ate neuronal progenitors born in the dentate neuroepithelium that give rise to granule neurons.

261 echanical model of the apical surface of the neuroepithelium that incorporates the effect of interkin

262 The olfactory epithelium is a sensory neuroepithelium that supports adult neurogenesis and tis

263 pit, multiple discrete regions of underlying neuroepithelium, the mandibular and maxillary arches, in

264 o increase from 9 to 13 h in the neocortical neuroepithelium, the maximum G(1) phase length attainabl

265 ment, Foxg1 directs development of the optic neuroepithelium through transcriptional suppression of W

266 he prevailing model assumes that the dentate neuroepithelium throughout the longitudinal axis of the

267 mpared its output to the growth of the chick neuroepithelium to assess the interplay between INM and

268 hanisms governing development of the retinal neuroepithelium to be probed in detail.

269 a paracrine signaling pathway that links the neuroepithelium to blood vessels and precisely balances

270 en progenitor cells migrate from the dentate neuroepithelium to establish a germinal zone in the hilu

271 o regulate the timing of the transition from neuroepithelium to neuroblast.

272 lly from the lateral ventricle dentate notch neuroepithelium to populate the tertiary matrix and form

273 ontinuous front in the Drosophila optic lobe neuroepithelium to produce neural stem cells (NSCs).

274 cells and newly born granule cells from the neuroepithelium to the dentate gyrus remains intact.

275 Thus, HSV-1 spread from the olfactory neuroepithelium to the TG and reemerged peripherally wit

276 population that travels from the prethalamic neuroepithelium to the ventral lateral geniculate nucleu

277 SPN migrated from the neuroepithelium to the ventrolateral spinal cord and the

278 l migration (prior to E11.5) of SPN from the neuroepithelium to the ventrolateral spinal cord is simi

279 totic SPN undergo primary migration from the neuroepithelium to the ventrolateral spinal cord, and th

280 SPN in the chick first migrate from the neuroepithelium to the ventrolateral spinal cord.

281 progenitors (OLPs) originate in the ventral neuroepithelium under the influence of Sonic hedgehog (S

282 originate from restricted domains of ventral neuroepithelium under the influence of sonic hedgehog pr

283 The olfactory neuroepithelium undergoes continual neurogenesis and, af

284 the new population derives largely from the neuroepithelium ventral and rostral to the ablation.

285 Knowledge of the vomeronasal neuroepithelium (VNNE) microanatomy is disproportionatel

286 on associated with enhanced apoptosis in the neuroepithelium was also observed.

287 isplacement of mitotic nuclei in the retinal neuroepithelium was observed in tvrm360 mice at postnata

288 A1 is most highly expressed in the embryonic neuroepithelium when the neural progenitors are highly p

289 t and endothelial makers were visible in the neuroepithelium where they generated vasculogenic and he

290 calizes to apical cell-cell junctions in the neuroepithelium, where it activates G protein signaling

291 hila optic lobe originate within a polarised neuroepithelium, where they divide symmetrically.

292 olated from the Fgfr1(Deltaflox) hippocampal neuroepithelium, whereas epidermal growth factor-sensiti

293 FoxD3 was abnormally retained in the dorsal neuroepithelium, whereas Sox10, which is normally requir

294 of terminals across the canalicular sensory neuroepithelium with morphophysiological studies in chin

295 tal process, Foxg1 is expressed in the optic neuroepithelium, with highest levels of expression in th

296 This correlates with an abnormal brain neuroepithelium, with no clear midline and disrupted jun

297 yer cultured hESCs into homogenous primitive neuroepithelium within 1 wk under chemically defined con

298 ies this squamous epithelium to the columnar neuroepithelium within the embryo's brain.

299 bular dysfunction due to degeneration of the neuroepithelium within the inner ear.

300 rs undergo dynamic rearrangements within the neuroepithelium, yielding an overall ventral to dorsal m