ライフサイエンスコーパス: neuronal circuit

1 ermined by the position it occupies within a neuronal circuit.

2 ogics that can efficiently repair or remodel neuronal circuits.

3 ed capacity to regenerate damaged tissue and neuronal circuits.

4 nt could play a role in integrating distinct neuronal circuits.

5 ctors that drive the formation of individual neuronal circuits.

6 nt modifications of synaptic strength within neuronal circuits.

7 for the remodeling of aberrant glutamatergic neuronal circuits.

8 rucial role in the formation and function of neuronal circuits.

9 and is a key step in the formation of mature neuronal circuits.

10 trieval requires knowledge of the underlying neuronal circuits.

11 sition is essential for the morphogenesis of neuronal circuits.

12 itive function at the level of molecular and neuronal circuits.

13 of axons, dendrites, and synapses that form neuronal circuits.

14 on orchestrated development of hypothalamic neuronal circuits.

15 sult have provided a wealth of insights into neuronal circuits.

16 sive disruption of excitatory and inhibitory neuronal circuits.

17 and is thought to regulate communication in neuronal circuits.

18 are critical for the appropriate function of neuronal circuits.

19 and thus their own function within specific neuronal circuits.

20 ner, thereby influencing the excitability of neuronal circuits.

21 nt and their importance for the formation of neuronal circuits.

22 mporal and cell type-selective modulation of neuronal circuits.

23 opment is required to refine the function of neuronal circuits.

24 essential for the formation and function of neuronal circuits.

25 necessary for generating correctly balanced neuronal circuits.

26 ical roles in the development of hippocampal neuronal circuits.

27 part of both the circadian and sleep-arousal neuronal circuits.

28 ions that enable precise assembly of complex neuronal circuits.

29 anticonvulsive drugs that target neurons or neuronal circuits.

30 part of both the circadian and sleep-arousal neuronal circuits.

31 integration of newborn neurons into complex neuronal circuits.

32 critical for development and regeneration of neuronal circuits.

33 e crucial for the appropriate functioning of neuronal circuits.

34 nd learning capacities of single neurons and neuronal circuits.

35 cific synaptic connectivity and formation of neuronal circuits.

36 associated with developmental refinements of neuronal circuits.

37 tion of the excitatory/inhibitory balance of neuronal circuits.

38 high glucose (HG) on individual neurons and neuronal circuits.

39 ling is essential to encode experiences into neuronal circuits.

40 mulation is a powerful tool for the study of neuronal circuits.

41 stood due to the high complexity of affected neuronal circuits.

42 s communication efficacy across a variety of neuronal circuits.

43 increasingly sophisticated understanding of neuronal circuits.

44 ntral to the functional stability of healthy neuronal circuits.

45 but can reveal invaluable information about neuronal circuits.

46 in a prion-like manner throughout connected neuronal circuits.

47 dent macrophages, critically shape forebrain neuronal circuits.

48 prevent neuronal loss or protect vulnerable neuronal circuits, a potential alternative is to replace

49 To facilitate the dissection of neuronal circuits, a process requiring functional analys

50 Neuronal circuits' ability to maintain the delicate bala

51 ntial activity has been observed in multiple neuronal circuits across species, neural structures, and

52 that consolidation selectively strengthened neuronal circuits activated by seizures.

53 The neuronal circuits activated during seizure spread from t

54 esponse is directly controlled by descending neuronal circuits activated in response to stress.

55 l metabolic and structural support, modulate neuronal circuit activity and may also function as versa

56 ptic plasticity" leads to changes in overall neuronal circuit activity, resulting in behavioral modif

57 nate to generate inappropriate regulation of neuronal circuit activity.

58 al models based on the canonical feedforward neuronal circuit and included electrical synapses betwee

59 ly contribute to developmental refinement of neuronal circuits and associated behaviors.

60 nceptual links between the function of local neuronal circuits and brain-wide network dynamics.

61 this review, we provide an update on the key neuronal circuits and cell types mediating conditioned f

62 whether it is consistent across a variety of neuronal circuits and dependent upon the type of informa

63 and invertebrate models, well-characterized neuronal circuits and evolutionarily conserved mechanism

64 ties, are mutually reinforcing; however, the neuronal circuits and mechanisms that underlie this rein

65 Here we sought to reveal the neuronal circuits and molecular basis of ADHD and its po

66 eurons into our current understanding of the neuronal circuits and molecular mechanisms of the LHA th

67 arned in trace conditioning, recruiting more neuronal circuits and molecular mechanisms than in delay

68 f non-reinforced repetitive stimuli, but the neuronal circuits and molecular mechanisms that underlie

69 Questions remain regarding which neuronal circuits and neurotransmitters trigger activati

70 -output relationship are applicable to other neuronal circuits and organisms.

71 ls does not selectively label taste-specific neuronal circuits and reveal local taste receptor gene e

72 The format represents neuronal circuits and simulation inputs and outputs via

73 ant roles of BDNF in regulating synapses and neuronal circuits and suggest that regulation of presyna

74 he creation of comprehensive network maps of neuronal circuits and systems.

75 crucial for the integration of neurons into neuronal circuits and the maintenance of the architectur

76 questions in epilepsy, to dissect epileptic neuronal circuits and to develop new intervention strate

77 ween neuronal subtypes drive the assembly of neuronal circuits and underlie the subtype specificity o

78 ression of pathological tau along vulnerable neuronal circuits, and demonstrates the utility of chron

79 hallenges resulting from ongoing activity in neuronal circuits, and from environmental energetic stre

80 round-breaking discoveries in gene-function, neuronal circuits, and physiological responses.

81 l of gene activity in neurons and integrated neuronal circuits, and provides a surprising link betwee

82 ding of how disease-related states, specific neuronal circuits, and various behavioral assays fit int

83 that the rules for astrocyte engagement in a neuronal circuit are fundamentally altered in a brain di

84 begin to define and test the rules by which neuronal circuits are assembled during development and u

85 Neuronal circuits are known to integrate nutritional inf

86 Cell, Xu et al. elegantly show that parallel neuronal circuits are necessary for two distinct roles o

87 ions needed for survival, yet the underlying neuronal circuits are poorly understood.

88 Neuronal circuits are shaped by experience during critic

89 mental developmental units of the brain, and neuronal circuits are the fundamental functional units o

90 The stereotyped features of neuronal circuits are those most likely to explain the r

91 Synapses, the fundamental unit in neuronal circuits, are critical for learning and memory,

92 neuropsychological scheme units, which have neuronal circuits as functional infrastructure, thus hel

93 Neuronal circuit assembly requires the fine balance betw

94 of central synapses is a key factor driving neuronal circuit behavior in the vertebrate CNS.

95 n is critical for unraveling the function of neuronal circuits but is challenging due to the limited

96 t, and human brains in a conserved subset of neuronal circuits but with species-dependent development

97 tal component of one of the first discovered neuronal circuits, but their function in motor control h

98 ed inhibition and excitation of two separate neuronal circuits by a single interneuron suggests a uni

99 transmitter release in the assembly of early neuronal circuits by assaying transcriptional identity,

100 experiences cause long-term modifications of neuronal circuits by modulating activity-dependent trans

101 lly affects the processing of information in neuronal circuits by reversibly changing the effective s

102 re we used molecular genetics to dissect the neuronal circuits by which the ISR gates cognitive proce

103 fiber system (GFS), a simple escape response neuronal circuit, by increasing targeting of the gap jun

104 Complicated neuronal circuits can be genetically encoded, but the un

105 which raises the question of how neurons and neuronal circuits can operate robustly over wide tempera

106 l, these data demonstrate the specificity of neuronal circuit changes induced by amphetamine, introdu

107 How do the components of neuronal circuits collaborate to select combinations of

108 xonal branching contributes substantially to neuronal circuit complexity.

109 te difference in the anatomy or functions of neuronal circuits containing inhibition, two basic motif

110 ed unprecedented knowledge about the precise neuronal circuits contributing to the expression and rec

111 ration); and within these two ends, specific neuronal circuits control the actual rhythmic pattern of

112 To understand how neuronal circuits control variability, we examined the p

113 ecific mode of regulatory control within the neuronal circuit controlling courtship, even though it i

114 ed the way we now understand and think about neuronal circuits controlling movement.

115 o evidence that fly glial cells modulate the neuronal circuits controlling rhythmic behaviors, includ

116 Neuronal circuits damaged or lost after injury can be re

117 The establishment of neuronal circuits depends on the guidance of axons both

118 hat the counteracting activities of distinct neuronal circuits determine the sexual identity of the p

119 newly formed spines, which are critical for neuronal circuit development and behavioral improvement

120 During neuronal circuit development, the spatial localization o

121 ry roles that vary during distinct stages of neuronal circuit development.

122 signaling networks known to be important for neuronal circuit development.

123 However, neuronal circuit diagrams typically draw upon anatomical

124 not selectively label taste quality-specific neuronal circuits due to lateral transfer of the tracer

125 tional connections between neurons to sculpt neuronal circuits during development and throughout adul

126 pses is a critical step in the refinement of neuronal circuits during development of the cerebral cor

127 ory, and it is crucial for the refinement of neuronal circuits during development.

128 activity regulate axon elimination to refine neuronal circuits during development.

129 Spontaneous network activity shapes emerging neuronal circuits during early brain development prior t

130 The proper development of neuronal circuits during neuromorphogenesis and neuronal

131 empower novel systems-level understanding of neuronal circuit dynamics and facilitate the design of m

132 (2020) identify neuronal circuit dynamics responsible for multiple level

133 ment of solution space in studies of complex neuronal circuit dynamics.

134 wing the genetically controlled formation of neuronal circuits, early firing activity guides the deve

135 wing the genetically controlled formation of neuronal circuits, early firing activity guides the deve

136 e monitoring the activity state of the local neuronal circuit electrophysiologically and optically.

137 ation, maintenance, and function in multiple neuronal circuits essential for important brain function

138 oid hormones can help reestablish functional neuronal circuits following degeneration in the adult br

139 ndings reveal a novel hypothalamic-hindbrain neuronal circuit for sleep/wake control.

140 NCE STATEMENT Eye movements rely on multiple neuronal circuits for appropriate performance.

141 essing neurons serve as a component of local neuronal circuits for processing itch sensation in the s

142 robust and hard wired, rely on modulation of neuronal circuits, for eliciting an appropriate response

143 ow myelinated axon plasticity contributes to neuronal circuit formation and function.

144 evidence that disrupting systems regulating neuronal circuit formation leads to early-onset obesity

145 oral dynamics to the static description of a neuronal circuit from single time-point connectomics exp

146 ferences about the computations performed by neuronal circuits from synapse-level connectivity maps i

147 ignaling plays important roles in regulating neuronal circuit function and behavior in C. elegans.

148 r uncovering the roles of GluN2C subunits in neuronal circuit function and in the development of new

149 ur understanding of the relationship between neuronal circuit function and symptoms of schizophrenia,

150 Pacemaker neurons exert control over neuronal circuit function by their intrinsic ability to

151 Neuronal circuit function is governed by precise pattern

152 native splicing of neurexins is critical for neuronal circuit function.

153 ichannels are both targets and modulators of neuronal circuit function.

154 provides an attractive model system to study neuronal circuit function.

155 ntions while limiting the effects on overall neuronal circuit function.

156 mental basis of behavior and deciphering how neuronal circuits function to regulate behavior.

157 ies that involve inflammatory mechanisms and neuronal circuit functions are ill-defined.

158 neuroscience is to determine how the brain's neuronal circuits generate perception, cognition and emo

159 cs is essential for the understanding of how neuronal circuits give rise to computations.

160 Several hypothalamic nuclei and neuronal circuits have been the focus of many studies se

161 We propose that the effects of these on neuronal circuits have profound implications for our und

162 Neuronal circuits have the capacity to maintain relative

163 to signals with rapidly varying statistics, neuronal circuits implementing predictive coding must al

164 tonigral/striatomesencephalic pathway, a key neuronal circuit implicated in positive 'Go' behavioral

165 A map of a neuronal circuit in a marine worm reveals how simple net

166 ent and presynaptic function in a developing neuronal circuit in its native environment is unclear.

167 the population level.SIGNIFICANCE STATEMENT Neuronal circuit in layer 2/3 of mouse area V1 possesses

168 is elegans implicate an ancient serotonergic neuronal circuit in the link between these two outputs -

169 Here, we identify a neuronal circuit in the nematode Caenorhabditis elegans

170 uring the functional dynamics of large-scale neuronal circuits in awake behaving mammals at high spee

171 eby contribute to the correct development of neuronal circuits in both invertebrates and mammals.

172 Neuronal circuits in early visual areas make these predi

173 ted viruses that can transsynaptically label neuronal circuits in either the retrograde or anterograd

174 science by enabling systematic recordings of neuronal circuits in living animals.

175 In this review, I discuss newly discovered neuronal circuits in primates that represent uncertainty

176 Neuronal circuits in the brain help to control feeding b

177 vents in the body, including the activity of neuronal circuits in the brain that are involved in cogn

178 n be used to investigate the connectivity of neuronal circuits in the brain.

179 Animal behavior is encoded in neuronal circuits in the brain.

180 tile stimuli are integrated and processed by neuronal circuits in the deep dorsal horn of the spinal

181 Leptin's effects on BP are mediated by neuronal circuits in the dorsomedial hypothalamus (DMH),

182 ant roles in the formation and plasticity of neuronal circuits in the hippocampus, a brain region of

183 ions that are essential for the operation of neuronal circuits in the neocortex.

184 rafish as a model to study the role of these neuronal circuits in the regulation of feeding, sleep, a

185 there is growing evidence of alterations in neuronal circuits in the sensory cortex of the mouse mod

186 We have developed computational models of neuronal circuits in the spinal cord that include left a

187 ing, are produced by coordinated activity in neuronal circuits in the spinal cord.

188 nosynaptic tracing has been used to identify neuronal circuits in various parts of the nervous system

189 nt approaches have been utilized to decipher neuronal circuits, including electron microscopy (EM) an

190 entifying signaling mechanisms that underlie neuronal circuit integration in the adult brain, we have

191 light sensitivity enable minimally invasive neuronal circuit interrogation.

192 been characterized in this organism and the neuronal circuits involved are well described.

193 Thus, a tripartite neuronal circuit involving a fast hyperpolarization and

194 Rewiring of excitatory glutamatergic neuronal circuits is a major abnormality in epilepsy.

195 Dysfunction of neuronal circuits is an important determinant of neurode

196 Dense connectomic mapping of neuronal circuits is limited by the time and effort requ

197 ether in functional groups or impact similar neuronal circuits is needed to develop rational treatmen

198 these patterns contribute to the assembly of neuronal circuits is not clearly understood.

199 lve activation of premotor spinal excitatory neuronal circuits is unknown.

200 egration of PV(+) interneurons into cortical neuronal circuits, leading to behavioral alterations in

201 disorders, pathophysiological stimulation of neuronal circuits leads to activity - dependent accelera

202 d manipulate memory function at the cell and neuronal circuit level has spurred an explosion of inter

203 eorganisation mechanistically emerges at the neuronal circuit level is still unclear.

204 gulated transcription.SIGNIFICANCE STATEMENT Neuronal circuits maintain relatively stable firing rate

205 Despite dynamic inputs, neuronal circuits maintain relatively stable firing rate

206 Neuronal circuit mapping using electron microscopy deman

207 tic tracing has become a standard method for neuronal circuit mapping, and is applied to virtually al

208 nologies are powerful experimental tools for neuronal circuit mapping.

209 synaptic transmission during early stages of neuronal circuit maturation.

210 he stimulus arises from shared input but the neuronal circuit mechanisms that result in these noise c

211 Agtr1a gene) influence these processes, the neuronal circuits mediating these effects are incomplete

212 We propose a neuronal circuit model that computes decision uncertaint

213 The minimal neuronal circuit necessary to direct peristalsis is well

214 n neuronal-glial function within hippocampal neuronal circuits of relevance to cognitive processing i

215 ty evoked by drugs of abuse in the so-called neuronal circuits of reward has been proposed to underli

216 The neuronal circuits of the basolateral amygdala (BLA) are

217 depends on autonomic reflexes controlled by neuronal circuits of the brainstem.

218 Neuronal circuits often display small-world network arch

219 Developing neuronal circuits often undergo a period of refinement t

220 The discovery is that neuronal circuits operating reflexively regulate innate

221 r understanding of the principles underlying neuronal circuit organization and function.

222 ed by increasing Ca(V)2.1 levels to regulate neuronal circuit output.

223 ongate, and precisely connect new functional neuronal circuits over long distances.

224 s system, experience-dependent refinement of neuronal circuits predominantly involves synapse elimina

225 lie adaptive behavior by rearranging the way neuronal circuits process information.

226 ld be immensely useful for understanding how neuronal circuits process information.

227 Neuronal circuits produce self-sustaining sequences of a

228 These findings illustrate that neuronal circuit properties can be modulated by adjustin

229 ht Wnt signaling as a targetable pathway for neuronal circuit recovery after synapse degeneration.

230 Neuronal circuits regulating hunger and satiety synthesi

231 The assembly of specific neuronal circuits relies on the expression of complement

232 onal properties and their role in regulating neuronal circuits remain unclear.

233 t are essential for survival, the underlying neuronal circuits remain undefined.

234 The VNC harbors neuronal circuits required to execute key behaviors, suc

235 Establishing a functional neuronal circuit requires not only synapsing with the ri

236 Maturation of neuronal circuits requires selective elimination of syna

237 The relevant chemoreceptors and the neuronal circuits responsible for arousal are largely un

238 otonergic innervation of the cortical-limbic neuronal circuit, RGS6 exerts powerful anxiogenic and pr

239 The neurophysiological mechanisms and the neuronal circuit(s) that generate these seizures are unr

240 utations on millisecond timescales, but some neuronal circuits set behavioral states over long time p

241 of feature-specific information conveyed by neuronal circuits.SIGNIFICANCE STATEMENT How we pay atte

242 ly contribute to developmental refinement of neuronal circuits.SIGNIFICANCE STATEMENT This report est

243 Here, we report a neuronal circuit that allows Drosophila larvae to overco

244 work in Drosophila identifies an excitatory neuronal circuit that builds up mating drive while primi

245 Here, we describe a neuronal circuit that couples the reproductive system an

246 stral cell type, a progenitor to the complex neuronal circuit that integrates sensory information and

247 From these data we propose a neuronal circuit that may be suited to stabilize the int

248 e physiological properties of lLNvs and on a neuronal circuit that may provide visual information to

249 lateral amygdala is an important node in the neuronal circuit that mediates defensive responses(6-9),

250 dow of juvenile adult brain development when neuronal circuits that are required for learning and mem

251 expressing neurons are key components of the neuronal circuits that control food intake and energy ho

252 Motoneurons are not mere output units of neuronal circuits that control motor behavior but partic

253 nerated sensory input.SIGNIFICANCE STATEMENT Neuronal circuits that control motor behaviors orchestra

254 Neuronal circuits that control motor behaviors orchestra

255 Neuronal circuits that control vocalization and breathin

256 past experiences is normally integrated into neuronal circuits that encode episodic memories and play

257 speptin neurons as active players within the neuronal circuits that govern energy balance is discusse

258 this variability to ensure the formation of neuronal circuits that maintain constant retinal coverag

259 reflect profound disruptions of activity in neuronal circuits that mediate awareness and cognition.

260 Our findings reveal that the neuronal circuits that mediate fear and anxiety overlap

261 ponding and its related pathologies, but the neuronal circuits that orchestrate these interactions ar

262 nt information and rescue flexibility in the neuronal circuits that process limbic memory formation.

263 Immune cell activation stimulates neuronal circuits that regulate innate and adaptive immu

264 Neuronal circuits that regulate movement are distributed

265 pport for one prominent hypothesis, based on neuronal circuits, that proposes the principal neocortic

266 Although vulnerable neurons are embedded in neuronal circuits, the contributions of their synaptic p

267 ed connectome that includes both partners in neuronal circuits-the neurons and the glial cells, provi

268 ient to develop specialized left lateralized neuronal circuits, thereby pointing to an early onset an

269 ation on arousal and/or stressful stimuli to neuronal circuits thus contributing to the many actions

270 activation of astrocytes switches the local neuronal circuit to this slow-oscillation state.

271 ture to identify the specific adaptations of neuronal circuits to environmental changes.

272 periences and learning continually shape our neuronal circuits to form new memories.

273 the healthy brain, from sculpting developing neuronal circuits to guiding learning-associated plastic

274 nsorimotor processing relies on hierarchical neuronal circuits to mediate sensory-driven behaviors.

275 uman behavior is dependent on the ability of neuronal circuits to predict the outside world.

276 ptic release in excitatory neurons, steering neuronal circuits towards epilepsy.

277 We combined behavioral tests with neuronal circuit tracing, morphology, chemogenetics, opt

278 In the idling brain, neuronal circuits transition between periods of sustaine

279 has provided a comprehensive picture of the neuronal circuit underlying the formation of fear memori

280 To compensate for this variability, neuronal circuits underlying economic decisions undergo

281 r whether distinct neurons modulate specific neuronal circuits underlying particular types of behavio

282 ting Ptf1a expression are key for generating neuronal circuits underlying somatosensory behaviors.

283 However, the precise neuronal circuits underlying the acquisition of cue-cont

284 tors were also of influence, suggesting that neuronal circuits underlying the development of addictio

285 imulate motion detection well, but the exact neuronal circuits undertaking these tasks remain elusive

286 er a way to probe the functionality of human neuronal circuits using physiological sensory stimuli.

287 but instead maintains a plastic hippocampal neuronal circuit via the continuous addition of immature

288 y the sparse and random connectivity of real neuronal circuits, we present a model for neural codes t

289 e elucidated the structure and physiology of neuronal circuits, we still only have a very limited und

290 Further, we delineate a sex-specific neuronal circuit wherein the P1 neurons encoding increas

291 gic neurotransmission could lead to abnormal neuronal circuits, which may contribute to neurological

292 ing mGluR5 expression could lead to abnormal neuronal circuits, which may contribute to neurological

293 s, a divergent molecular mechanism regulates neuronal circuit wiring in the Drosophila brain, partly

294 These neurons are part of a neuronal circuit with dynamics resembling those of a rin

295 o inhibitory synapses form the hardwiring of neuronal circuits with receptors of a different composit

296 t enable the analysis of genetically defined neuronal circuits with unprecedented specificity and pre

297 ion, supporting the existence of a locomotor neuronal circuit within these MRF in behaving primates.

298 Neuronal circuits within the prefrontal cortex (PFC) med

299 l cord requires the computation of the local neuronal circuits within the same segments as well as th

300 ave prevented the removal of astrocytes from neuronal circuits without changing other important condi