ライフサイエンスコーパス: neurosurgical

1 Adult neurologic and neurosurgical 1,118 patients in the pre period, 731 pati

2 wo groups: endovascular 83% (626 of 755) and neurosurgical 82% (584 of 713).

3 ive-compulsive disorder (OCD) have undergone neurosurgical ablation for more than half a century.

4 of neuroleptics, deep-brain stimulation, and neurosurgical ablation for treatment-resistant OCD.

5 uld have access to the potential benefits of neurosurgical advances.

6 ic validation cohort comprised patients from neurosurgical and intensive care centers in Edinburgh an

7 itrous oxide as a component of anesthesia in neurosurgical and neurologically at-risk patients.

8 ne are among the most common indications for neurosurgical and orthopedic surgical interventions.

9 ntraoperative navigation during a variety of neurosurgical and other types of surgical procedures.

10 AVMs is an efficient and safe alternative to neurosurgical and radiosurgical methods.

11 terviewees were from open medical, surgical, neurosurgical, and cardiovascular ICUs.

12 eep brain stimulation (DBS) is a widely used neurosurgical approach to treating tremor and other move

13 Neurosurgical approaches are available such as capsuloto

14 roposed as a noninvasive alternative to open neurosurgical approaches to manage a variety of conditio

15 t will be needed to determine whether a sham neurosurgical arm should be included in clinical trials

16 The inclusion of a sham neurosurgical arm will be guided in part by the objectiv

17 age, 45 +/- 15 y) who had been referred for neurosurgical assessment of unclear brain lesions and ha

18 luding blood-brain barrier (BBB) disruption, neurosurgical-based approaches, and molecular design.

19 ng and peritumoral nonenhancing stereotactic neurosurgical biopsy samples from treatment-naive GBMs w

20 blishment of narrower selection criteria for neurosurgical candidacy, together with a better understa

21 for preoperative language lateralization in neurosurgical candidates.

22 head injury, and to establish the effect of neurosurgical care on mortality after severe head injury

23 nd committed to, operative and postoperative neurosurgical care.

24 chest tubes, diagnostics, and orthopedic and neurosurgical care; mean ratings </= 2).

25 t guidelines, suggesting that treatment in a neurosurgical centre represents an important strategy in

26 nts with severe head injury are treated in a neurosurgical centre.

27 hose treated in a neurosurgical versus a non-neurosurgical centre.

28 case mix compared with patients treated at a neurosurgical centre.

29 longitudinal, observational study done in 56 neurosurgical centres across China.

30 ms were enrolled between 1994 and 2002 at 43 neurosurgical centres and randomly assigned to clipping

31 We followed up 1644 patients in 22 UK neurosurgical centres for death and clinical outcomes fo

32 ting less than 96 h from ictus from 35 acute neurosurgical centres in nine countries.

33 At 13 neurosurgical centres in the UK, between November, 2000,

34 racranial aneurysms, who were admitted to 42 neurosurgical centres, mainly in the UK and Europe, took

35 ween 1996 and 2003) were treated only in non-neurosurgical centres; such treatment was associated wit

36 They were randomly assigned to neurosurgical clipping (n=1070) or endovascular coiling

37 , patients were randomly allocated to either neurosurgical clipping or endovascular coiling after a s

38 a ruptured intracranial aneurysm with either neurosurgical clipping or endovascular coiling.

39 ling and 657 (79%) of 835 patients allocated neurosurgical clipping were alive (odds ratio [OR] 1.35,

40 coiling and 370 (78%) patients treated with neurosurgical clipping were independent (modified Rankin

41 likely after endovascular coiling than after neurosurgical clipping, but the risk was small and the p

42 common after endovascular coiling than after neurosurgical clipping.

43 with endovascular procedures and 49.23% with neurosurgical clipping.

44 esult in independent survival at 1 year than neurosurgical clipping; the survival benefit continues f

45 significant reduction (19.0%) in the rate of neurosurgical consultation (post-BIG group, 273 patients

46 s the management of TBI without the need for neurosurgical consultation and unnecessary imaging.

47 e of corticosteroids, if possible, and early neurosurgical consultation for stereotactic biopsy.

48 equiring prompt anticoagulation reversal and neurosurgical consultation.

49 Proportion of patients who received neurosurgical consultations (P < 0.001) and repeat head

50 repeated computed tomography of the head and neurosurgical consultations.

51 (CSF) accumulation and thereby treated with neurosurgical CSF diversion with high morbidity and fail

52 bilitating neurological condition, for which neurosurgical cure is possible.

53 established and patient was referred to the Neurosurgical Department.

54 DESIGN, SETTING, AND PATIENTS: Both neurosurgical departments are exclusive providers in adj

55 iew of hydrocephalus from that of a lifelong neurosurgical disorder to that of a preventable neuroinf

56 Hydrocephalus is the most common neurosurgical disorder worldwide and is characterized by

57 he pathogenesis of the most common pediatric neurosurgical disorder.

58 (TM) - a clinical biomaterial used widely in neurosurgical duraplasty procedures, to support the grow

59 ntact depth electrodes implanted in HG of 14 neurosurgical epilepsy patients as they vocalized vowel

60 Using recordings from neurosurgical epilepsy patients with intracranially impl

61 amyloid beta through putatively contaminated neurosurgical equipment.

62 5% CI 5.7 to 7.5) per 100 person-years after neurosurgical excision (median follow-up 3.3 years) and

63 g cerebral cavernous malformations (CCMs) by neurosurgical excision or stereotactic radiosurgery are

64 sks of CCM treatment (and the lower risks of neurosurgical excision over time, from recently bled CCM

65 After neurosurgical excision the incidence of the composite ou

66 intervention (any endovascular embolization, neurosurgical excision, or stereotactic radiosurgery alo

67 to available medication and may benefit from neurosurgical excisional surgery.

68 A potential solution is to use neurosurgical grade materials routinely used in clinical

69 ing childhood exposure to cadaveric dura (by neurosurgical grafting in 2 patients and tumor embolizat

70 reater in the endovascular group than in the neurosurgical group at 10 years.

71 and 14% (144 of 1041) of the patients in the neurosurgical group had died (log-rank p=0.03).

72 dependency was significantly greater in the neurosurgical group than in the endovascular group.

73 cal procedures (general surgery, orthopedic, neurosurgical, gynecologic, and urologic) in adult patie

74 Patients admitted to the neurological or neurosurgical ICU are likely to have palliative care nee

75 CH is the most common neurosurgical indication in children effecting 1 per 100

76 peutic resection for focal epilepsy or other neurosurgical indications by applying high-dimensional m

77 nd were enrolled within 6 hours of injury at neurosurgical intensive care units in 2 US level I traum

78 history in the cardiac, cardiothoracic, and neurosurgical intensive care units.

79 None of the 2,823 low-risk patients required neurosurgical intervention (negative predictive value [N

80 re-BIG group, 59 patients [14.2%]; P = .14), neurosurgical intervention (post-BIG group, 61 patients

81 risk status to 420 of 420 patients requiring neurosurgical intervention (sensitivity, 100.0% [95% con

82 2,823 of 11,350 patients who did not require neurosurgical intervention (specificity, 24.9% [95% CI:

83 istently in detecting MMTBI, CT lesions, and neurosurgical intervention across 7 days.

84 ing "high-risk" status to patients requiring neurosurgical intervention among a cohort of 11,770 blun

85 including 111 patients (1.43%) who required neurosurgical intervention and 306 (3.94%) who had signi

86 cal care coupled with timely and appropriate neurosurgical intervention can produce significant impro

87 The balance of risk and benefit from early neurosurgical intervention for conscious patients with s

88 Neurosurgical intervention for subdural hematoma decreas

89 In recent years, the safety and efficacy of neurosurgical intervention has rapidly improved for brai

90 In our study, the Canadian criteria for neurosurgical intervention identified 108 of 111 patient

91 vere traumatic brain injury (TBI) in need of neurosurgical intervention is complicated in a situation

92 ion: Abnormal CSF flow and the necessity for neurosurgical intervention must be considered when attem

93 No patient required neurosurgical intervention of their anterior temporal ED

94 : Proportion of patients with TBI in need of neurosurgical intervention per GCS score or Simplified M

95 Neurosurgical intervention remains the first step in eff

96 s of drug-resistant epilepsy, often requires neurosurgical intervention targeting seizure foci, such

97 ion identified 108 of 111 patients requiring neurosurgical intervention to yield a sensitivity of 97.

98 ce of injuries leading to death or requiring neurosurgical intervention was 0.9% (95% CI, 0.78%-1.0%)

99 Acute neurosurgical intervention was rare (3 of 86 total cases

100 with severe TBI and severe TBI in need of a neurosurgical intervention were similar in patients pres

101 dies, 237 (85%) were normal, 9 (3%) required neurosurgical intervention, 25 (9%) were delayed, and 7

102 ial pressure monitoring, vasopressors, acute neurosurgical intervention, and extracranial operation.

103 creening of intracranial injuries in need of neurosurgical intervention, but may also provide informa

104 hage on repeated computed tomographic scans, neurosurgical intervention, hospital admission, intensiv

105 The primary outcome was the composite of neurosurgical intervention, intubation for more than 24

106 r distinguishing patients with and without a neurosurgical intervention, the range for GFAP was 0.91

107 ohort, identified all 111 patients requiring neurosurgical intervention, yielding a sensitivity of 10

108 ic intracranial lesions on head CT scan, and neurosurgical intervention.

109 entify patients with severe TBI in need of a neurosurgical intervention.

110 identify patients with severe TBI in need of neurosurgical intervention.

111 nt that the patient may no longer be fit for neurosurgical intervention.

112 re reveals important opportunities for early neurosurgical intervention.

113 medications, concurrent ischemic stroke, and neurosurgical intervention.

114 y outcome, including 8.3% (n = 70) who had a neurosurgical intervention.

115 Despite referral bias, services offering neurosurgical interventions and health service planning

116 Neurosurgical interventions can be effective therapeutic

117 most effective supportive, therapeutic, and neurosurgical interventions for tuberculous meningitis t

118 heir ability to identify patients in need of neurosurgical interventions, no difference was found bet

119 mal in psychiatric disorders and affected by neurosurgical interventions, such as deep brain stimulat

120 h subcortical nuclei have been the target of neurosurgical lesions as well as deep brain stimulation

121 y to reappear a quarter century later in the neurosurgical literature.

122 apid identification, medical management, and neurosurgical management, when indicated, are essential

123 ch patients would most benefit from invasive neurosurgical monitoring and we present a novel radiolog

124 December 2016 with a TBI requiring invasive neurosurgical monitoring was performed.

125 egies that are essential for next-generation neurosurgical oncologists and major brain tumor centers.

126 ients (30%) with GCS scores of 3 to 14 had a neurosurgical operation (P < .001).

127 1%) with a GCS score of 15 were in need of a neurosurgical operation, and fewer than 51 of the 171 pa

128 the electrocorticogram recorded during awake neurosurgical operations in Broca's area and in the domi

129 urgical specialties: general, gynecological, neurosurgical, oral, orthopedics, otolaryngologic, plast

130 general, vascular, thoracic, genitourinary, neurosurgical, orthopedic, or spine surgery from October

131 ollection of reference images for label-free neurosurgical pathology.

132 usion-related morbidity and mortality in the neurosurgical patient are limited.

133 Perioperative transfusion thresholds in the neurosurgical patient are undefined.

134 y from prefrontal depth electrodes in a rare neurosurgical patient while he performed the Iowa Gambli

135 nt understanding of blood transfusion in the neurosurgical patient, as well as other blood component

136 e intraoperative management of the pediatric neurosurgical patient.

137 n the anesthetic management of the pediatric neurosurgical patient.

138 Eight neurosurgical patients (5 male; 3 female) listened to se

139 works of the human brain, we recruited seven neurosurgical patients (four males and three females) wh

140 euron recordings from the amygdalae of human neurosurgical patients (male and female) while they lear

141 on of intensive care unit management for all neurosurgical patients after brain tumor resection are n

142 om 489 single neurons in the amygdalae of 41 neurosurgical patients and found a categorical selectivi

143 e, we administered a free recall test to 114 neurosurgical patients and used intracranial theta and h

144 rdings from the primary and nonprimary AC in neurosurgical patients as they listened to multi-talker

145 orded invasively from the auditory cortex of neurosurgical patients as they listened to speech, this

146 ons, we performed intracranial recordings in neurosurgical patients as they reported their perception

147 onses from 630 parahippocampal neurons in 24 neurosurgical patients during visual stimulus presentati

148 tral neural activity, based on data from 294 neurosurgical patients fitted with indwelling electrodes

149 ive versus liberal transfusion strategies in neurosurgical patients has been controversial.

150 a that may be used by doctors to advise post-neurosurgical patients if they can safely fly.

151 activation to test this prediction in human neurosurgical patients implanted with intracranial elect

152 neurons and local field potentials in human neurosurgical patients in two prefrontal regions critica

153 in the human hippocampus and amygdala while neurosurgical patients made memory retrieval decisions t

154 As thirteen neurosurgical patients performed a person recognition ta

155 ments and hippocampal field potentials while neurosurgical patients performed a spatial memory task.

156 Neurosurgical patients performed this task as we recorde

157 espread cortical and subcortical sites as 20 neurosurgical patients performed working memory tasks.

158 d single-neuron activities and LFPs in human neurosurgical patients performing a face/nonface categor

159 Recording neuronal activity from neurosurgical patients performing a virtual-navigation t

160 ing by recording single-neuron activity from neurosurgical patients performing a virtual-reality obje

161 ed recordings of single-neuron activity from neurosurgical patients playing a virtual-navigation vide

162 ors, we recorded single-neuron activity from neurosurgical patients playing Treasure Hunt, a virtual-

163 ocorticographic recordings taken as 46 human neurosurgical patients studied and freely recalled lists

164 electrocorticographic recordings taken as 69 neurosurgical patients studied and recalled lists of wor

165 ocorticographic recordings taken as 68 human neurosurgical patients studied and subsequently recalled

166 e-unit activity in multiple brain regions of neurosurgical patients to better characterize spindle ac

167 , we studied the responses of MTL neurons in neurosurgical patients to known concepts (people and pla

168 We asked 189 neurosurgical patients to perform a verbal free-recall t

169 overage of iEEG recordings in 12 eye-tracked neurosurgical patients to test whether a similar stabili

170 No neurosurgical patients were identified in our cohort.

171 We recorded the activity of MTL neurons in neurosurgical patients while they learned new associatio

172 analyzed intracranial brain recordings from neurosurgical patients while they studied lists of visua

173 gle neurons within the amygdalae of two rare neurosurgical patients with ASD.

174 limitation in reporting on 20 pre-operative neurosurgical patients with focal lesion to the pre- and

175 In this study, we used fMRI in five neurosurgical patients with focal vmPFC lesions to test

176 l gap through a novel application of fMRI in neurosurgical patients with focal, bilateral ventromedia

177 unctional magnetic resonance imaging in four neurosurgical patients with focal, bilateral vmPFC damag

178 ver 200 single neurons in the amygdalae of 7 neurosurgical patients with implanted depth electrodes.

179 Neurosurgical patients with implanted electrodes perform

180 act volunteers were included: six ambulatory neurosurgical patients with parenchymal ICP-sensors and

181 In this pilot study of 20 neurosurgical patients without glaucoma, posture-induced

182 Anemia is common in neurosurgical patients, and is associated with secondary

183 is a potentially devastating complication in neurosurgical patients, and plasma fibrinogen concentrat

184 rature of distinct cortical regions in awake neurosurgical patients, and we relate this perturbation

185 In critically ill neurologic and neurosurgical patients, elevated body temperature is com

186 te early bacterial meningitis development in neurosurgical patients, enabling earlier diagnostic cert

187 Recording from 20 neurosurgical patients, we directly examined the relatio

188 ing from over 200 neurons in the amygdala of neurosurgical patients, we found robust encoding of the

189 edial temporal lobe (MTL) recordings from 96 neurosurgical patients, we show that time series models

190 Using direct cortical surface recordings in neurosurgical patients, we studied the evolution of acti

191 ter their procedures, such as orthopedic and neurosurgical patients.

192 irectly using multielectrode recordings from neurosurgical patients.

193 s of aseptic and bacterial meningitis within neurosurgical patients.

194 en and how aggressively to transfuse RBCs in neurosurgical patients.

195 idence to guide RBC transfusion practices in neurosurgical patients.

196 that highlight issues in RBC transfusion in neurosurgical patients.

197 and unit firing in multiple brain regions of neurosurgical patients.

198 t the dogmatic avoidance of nitrous oxide in neurosurgical patients.

199 wn to be a predictor of poor outcome in many neurosurgical patients.

200 nctional MRI in the preoperative planning of neurosurgical patients.

201 d; the majority of previous reports describe neurosurgical patients.

202 Previous reports consisted predominantly of neurosurgical patients.

203 hy adults, and single-neuron recordings in 9 neurosurgical patients.

204 ntracranial hemorrhage, play a vital role in neurosurgical planning or can be misidentified as seriou

205 uate it in 3D on 60 brain tumor datasets for neurosurgical planning purposes.

206 egarding the use of this drug in the general neurosurgical population.

207 r the abscess was identified after a primary neurosurgical procedure (n = 43) or was a spontaneous ab

208 re, two patients did not have a history of a neurosurgical procedure and had community-acquired anaer

209 Deep brain stimulation (DBS) is a neurosurgical procedure that allows targeted circuit-bas

210 DBS is an increasingly common neurosurgical procedure that has been successfully used

211 The patient underwent an emergency neurosurgical procedure.

212 ime of cerebral circulation intervention for neurosurgical procedure.

213 entricular drain (EVD) insertion is a common neurosurgical procedure.

214 Many neurosurgical procedures are associated with significant

215 onsiderations for thoracic and thoracoscopic neurosurgical procedures are considered, emphasizing the

216 oaches in the context of patients undergoing neurosurgical procedures for medical treatment.

217 Data collected during awake neurosurgical procedures for the treatment of epilepsy p

218 For more than half a century, stereotactic neurosurgical procedures have been available to treat pa

219 e-neuronal activity in human subjects during neurosurgical procedures involving microelectrode record

220 emaining refractory to 'standard' therapies, neurosurgical procedures may be considered.

221 hat neuroimaging findings, stratification by neurosurgical procedures performed, and genomic informat

222 tive transfusion management for intracranial neurosurgical procedures presents the clinician with mul

223 cialized nature of these and other pediatric neurosurgical procedures prompt calls for similarly trai

224 ovel therapeutics as well as optimization of neurosurgical procedures to remove the tumor tissue are

225 Clinical events including neurosurgical procedures were identified using validated

226 nt for hydrocephalus is one of the commonest neurosurgical procedures worldwide.

227 uently associated with neurological disease, neurosurgical procedures, and use of psychoactive drugs.

228 ly used for a variety of adult and pediatric neurosurgical procedures, but also its use has expanded

229 ctors and in patients admitted from home for neurosurgical procedures, routine admission surveillance

230 ch, and electrocauterization when performing neurosurgical procedures, which is termed as surgical br

231 ortex samples obtained at autopsy and during neurosurgical procedures.

232 nts undergoing craniotomies for a variety of neurosurgical procedures.

233 rain injury (SBI) is unavoidable during many neurosurgical procedures.

234 e in the anesthetic management of functional neurosurgical procedures.

235 e imaging is steadily gaining acceptance for neurosurgical procedures.

236 acological intervention, and orthopaedic and neurosurgical procedures.

237 alformations (CMI), syringomyelia, and after neurosurgical procedures.

238 8%) were deemed capable of consenting to the neurosurgical RCT by all 5 psychiatrists.

239 those deemed incapable of consenting to the neurosurgical RCT were found capable of appointing a res

240 to a drug RCT, and capacity to consent to a neurosurgical RCT.

241 Neurosurgical resection and medical therapy with bromocr

242 TMEs), we utilized 5-ALA fluorescence-guided neurosurgical resection and sampling, followed by proteo

243 imens from 31 meningioma patients undergoing neurosurgical resection at Brigham and Women's Hospital

244 quency and may be a potential alternative to neurosurgical resection in some cases, though long-term

245 Neurosurgical resection is the standard treatment for su

246 roperties of GBM result in residual tumor at neurosurgical resection margins, representing the source

247 y be free of seizures during the years after neurosurgical resection of epileptogenic tissue.

248 g lymphocytes (TIL) from patients undergoing neurosurgical resection of glioblastoma multiforme (GBM)

249 g has the potential to significantly improve neurosurgical resection of oncologic lesions through imp

250 For people with refractory focal epilepsy, neurosurgical resection offers the possibility of a life

251 and permanent disconnection (resulting from neurosurgical resection) on interference control process

252 oma guides the decision to pursue definitive neurosurgical resection.

253 e and derived cells from patients undergoing neurosurgical resection.

254 Human brain slice cultures derived from neurosurgical resections may offer novel avenues to appr

255 aoperative magnetic resonance imaging in the neurosurgical setting.

256 regarding its prognostic significance in the neurosurgical setting.

257 est in the intraoperative and extraoperative neurosurgical setting.

258 36% vs 25%, p<0.001) and World Federation of Neurosurgical Societies (WFNS) Grade 4 or 5 (42.6% vs 28

259 &H (0.794; p < 0.001) or World Federation of Neurosurgical Societies (WFNS) scale (0.775; p < 0.01).

260 r results than clinical (World Federation of Neurosurgical Societies (WFNS), Hunt & Hess (HH) and rad

261 independent of age, sex, World Federation of Neurosurgical Societies score, modified Fisher score, tr

262 dmitted with poor-grade (World Federation of Neurosurgical Societies, 3-5) subarachnoid hemorrhage.

263 ontinental and international psychiatric and neurosurgical societies, joined efforts to further elabo

264 assignment, which was only disclosed to the neurosurgical staff at the time of operation.

265 used electrocorticography recordings from 16 neurosurgical subjects implanted with grids of electrode

266 erior-posterior length of the hippocampus as neurosurgical subjects performed a virtual spatial navig

267 ecording electrocorticographic activity from neurosurgical subjects performing auditory repetition ta

268 This has precipitated a crisis in access to neurosurgical support in many trauma systems, often plac

269 The subthalamic nucleus is the preferred neurosurgical target for deep-brain stimulation to treat

270 e portions of the CB identified in humans as neurosurgical targets for amelioration of psychiatric di

271 that are likely to be captured at different neurosurgical targets.

272 Only the neurosurgical team was aware of treatment assignments.

273 nd study personnel with the exception of the neurosurgical team were masked to treatment assignment.

274 vent of enhanced neuroimaging and functional neurosurgical techniques, a unique window of opportunity

275 europsychiatric disorders, brain targets and neurosurgical techniques, taking into account cultural a

276 siologic testing is an integral part of many neurosurgical techniques, the need to provide sufficient

277 ioural interventions and pharmacological and neurosurgical therapies.

278 Deep brain stimulation is an established neurosurgical therapy for movement disorders including e

279 subthalamic nucleus (STN) is the most common neurosurgical treatment for Parkinson's disease motor sy

280 Improved neurosurgical treatment has resulted in amblyopia replac

281 Controlled studies on the effect of neurosurgical treatment in patients with spontaneous cer

282 Neurosurgical treatment is appealing for selected people

283 Neurosurgical treatment may improve seizures in children

284 lts may represent early steps toward a novel neurosurgical treatment modality for alcohol dependence

285 halamic nucleus (STN) is the main target for neurosurgical treatment of motor signs of Parkinson's di

286 s Holmes tremor circuit was then compared to neurosurgical treatment targets and clinical efficacy.

287 In cases with effective neurosurgical treatment, the treatment target was connec

288 ment, and 1055 of 1070 patients allocated to neurosurgical treatment.

289 efit from or are not suitable for first-line neurosurgical treatment.

290 and function were impaired even years after neurosurgical trigeminal damage, suggesting that assessm

291 AH admitted to the West of Scotland regional neurosurgical unit 10 years previously.

292 We prospectively identified admissions to a Neurosurgical Unit for head injury, collected demographi

293 61 patients who were admitted to a regional neurosurgical unit were examined.

294 jury to craniotomy and direct admission to a neurosurgical unit were not found to be significant prog

295 adjusted odds ratio, 2.64 [1.14, 6.10]), and neurosurgical units (adjusted odds ratio, 2.96 [1.51, 5.

296 supratentorial intracerebral haemorrhage in neurosurgical units show no overall benefit from early s

297 icentre cohort study of EVD insertions in 21 neurosurgical units was performed over 6 months.

298 to recruit 100 patients from United Kingdom Neurosurgical Units within 12 months.

299 tant types of aura, demographic, clinical or neurosurgical variables.

300 hout head injury, and for those treated in a neurosurgical versus a non-neurosurgical centre.