ライフサイエンスコーパス: neurotoxin

1 rmed for Clostridium botulinum and botulinum neurotoxin.

2 e world are exposed to lead, a developmental neurotoxin.

3 cury and increase circulating levels of this neurotoxin.

4 s dopaminergic neurons against a PD-inducing neurotoxin.

5 ut seafood can also contain methyl mercury-a neurotoxin.

6 suggest a role of this metabolite as a weak neurotoxin.

7 crease soluble Abeta, likely the proximal AD neurotoxin.

8 used by consuming foods containing botulinum neurotoxin.

9 ium channel, the presumed destination of the neurotoxin.

10 ch is omnipresent in human life, is a potent neurotoxin.

11 an illness caused by types A and B botulinum neurotoxin.

12 human neuromuscular signaling by snake alpha-neurotoxins.

13 of different brain cell types in response to neurotoxins.

14 ease, essential for maturing of spider venom neurotoxins.

15 otentially fatal paralytic illness caused by neurotoxins.

16 vant for heterodimerization of a subgroup of neurotoxins.

17 opening, as the target for these amphipathic neurotoxins.

18 ol for discriminative detection of different neurotoxins.

19 roup of nonconventional "three-finger" snake neurotoxins.

20 NTs) form a large class of potent and deadly neurotoxins.

21 regulation of mAChRs by "three-finger" snake neurotoxins.

22 und to develop novel inhibitors of botulinum neurotoxins.

23 in survival in PC-12 cells treated with the neurotoxins.

24 elated metalloprotease domain of clostridial neurotoxins.

25 inium (MPP(+)), the active metabolite of the neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine,

26 ve effects associated with the mitochondrial neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine.

27 ormalities, the uptake of monoamines and the neurotoxin 1-methyl-4-phenylpyridinium was significantly

28 etitive OCT1 ligands, of which an endogenous neurotoxin, 1-benzyl-1,2,3,4-tetrahydroisoquinoline, was

29 Injection of the serotonergic neurotoxin 5,7-dihydroxytryptamine into the third ventri

30 Sublethal amounts of the neurotoxin 5,7-dihydroxytryptamine known to specifically

31 -2a and human SH-SY5Y - after treatment with neurotoxin 6-hydroxydopamine (6-OHDA), leading to the bi

32 pamine receptors in explant culture with the neurotoxin 6-hydroxydopamine at early stages of gland de

33 ative injury following administration of the neurotoxin 6-hydroxydopamine.

34 e obtained when worms were exposed to the DA neurotoxin 6-hydroxydopamine.

35 Botulinum neurotoxin A (BoNT/A) belongs to the most dangerous clas

36 Botulinum neurotoxin A (BoNT/A) has intrinsic endoprotease activit

37 Botulinum neurotoxin A (BoNT/A) is one of the most deadly toxins a

38 Here we present VHHs against botulinum neurotoxin A (BoNT/A) on the surface of red blood cells

39 lood cells to express VHHs against botulinum neurotoxin A (BoNT/A) on their surface and show that an

40 rapid and sensitive immunoassay of botulinum neurotoxin A (BoNT/A).

41 gned to address the light chain of Botulinum Neurotoxin A and Ricin Toxin A chain, which could be spe

42 BAcTrace is based on Clostridium botulinum neurotoxin A, Botox, which we engineered to travel retro

43 r alpha-bungarotoxin and similar snake alpha-neurotoxins also targeting alpha7 nAChR.

44 Acrylamide (AA) is a known lethal neurotoxin and carcinogen.

45 s have categorized microcystins as a kind of neurotoxin and carcinogen.

46 Methylmercury is a neurotoxin and endocrine disruptor and may impair avian

47 RNases (EARs): the human eosinophil-derived neurotoxin and eosinophilic cationic protein, and their

48 Using a catecholamine-specific neurotoxin and hyperinsulinemic-hypoglycemic clamps, we

49 e oligomeric (oAbeta), considered a proximal neurotoxin and neuroinflammatory stimuli.

50 Acrylamide is a neurotoxin and potential carcinogen, but is found in var

51 ented the deleterious effects exerted by the neurotoxin and related metabolite quinolinic acid (QUIN)

52 Acrylamide a neurotoxin and strong carcinogen, is found in various th

53 ility to copper, a metal that in excess is a neurotoxin and whose depletion constitutes a micronutrie

54 apture in C. catus requires both fast-acting neurotoxins and a delivery system quick enough to exceed

55 re it serves as a precursor to siderophores, neurotoxins and antibiotics.

56 Spider venom neurotoxins and cytolytic peptides are expressed as elon

57 level of VGluT2 upregulation in response to neurotoxins and its impact on postlesional plasticity.

58 he scallop uses hepatopancreas to accumulate neurotoxins and kidney to transform to high-toxicity for

59 3FTx) family, with high sequence identity to neurotoxins and low identity to the well-characterized 3

60 enhance throughput for routine evaluation of neurotoxins and novel therapeutics.

61 t role in protecting the brain from cationic neurotoxins and other potentially toxic organic cations.

62 on the study of the evolution of clostridial neurotoxins and provides the basis for the use of P. bif

63 er and energy devices, as well as injectable neurotoxins and soft-tissue augmentation materials, amon

64 noaminergic system is susceptible to uraemic neurotoxins and that this system is responsible for the

65 c dermatologic procedures, including energy, neurotoxin, and filler procedures, are safe when perform

66 dy demonstrates the suitability of botulinum neurotoxin, and serotype D in particular, as a basis for

67 RNASE2 encodes eosinophil-derived neurotoxin, and the rs3827907 C-allele appeared to parti

68 Spider neurotoxins are commonly used as pharmacological tools a

69 We determined that all three neurotoxins are enzymatically active.

70 Botulinum neurotoxins are known to have seven serotypes (BoNT/A-G)

71 Peptide neurotoxins are powerful tools for research, diagnosis,

72 Botulinum neurotoxins are the most toxic of all compounds.

73 Neurotoxins associated with Parkinson's disease fully en

74 ble treatment antitoxin which can target the neurotoxin at the extracellular level and cannot reverse

75 that shields the ion-selectivity filter from neurotoxin attack.

76 tive to the therapeutic effects of botulinum neurotoxin B (BoNT/B) than the animal models it is teste

77 replacing it with M/C/V/Q enhances botulinum neurotoxin B binding to human synaptotagmin II.

78 Mutant botulinum neurotoxin B containing E1191M/S1199Y exhibits 11-fold h

79 g neurotransmission than wild-type botulinum neurotoxin B in neurons expressing human synaptotagmin I

80 Botulinum neurotoxin B is a Food and Drug Administration-approved

81 The engineered botulinum neurotoxin B provides a platform to develop therapeutic

82 Here we engineered botulinum neurotoxin B so that it can be activated with blue light

83 g affinity to h-Syt II may improve botulinum neurotoxin B's therapeutic efficacy and reduce adverse e

84 arget influenza haemagglutinin and botulinum neurotoxin B, along with 6,286 control sequences to prob

85 en in the Syt II-binding pocket of botulinum neurotoxin B.

86 The steroidal neurotoxin (-)-batrachotoxin functions as a potent agoni

87 nd it is a known target of the environmental neurotoxin beta-methylamino-L-alanine (BMAA).

88 domain and replacing it with a C. botulinum neurotoxin binding domain.

89 rs were co-transported with both the tetanus neurotoxin-binding fragment and the membrane proteins th

90 First, clostridial neurotoxins block neurotransmission to or from neurons b

91 Tetanus neurotoxin (TeNT) and botulinum neurotoxin (BoNT) are clostridial neurotoxins (CNTs) res

92 Botulinum neurotoxin (BoNT) binds to and internalizes its light ch

93 Botulinum neurotoxin (BoNT) detection provides a useful model for

94 ensitive detection of highly toxic botulinum neurotoxin (BoNT) from Clostridium botulinum is of criti

95 t germinate, multiply, and produce botulinum neurotoxin (BoNT) in the immature intestine.

96 laccid paralysis of muscles due to botulinum neurotoxin (BoNT) intoxication.

97 ic disease caused by the action of botulinum neurotoxin (BoNT) on nerve cells.

98 Botulinum neurotoxin (BoNT) serotype A is the most lethal known to

99 covered which produces two toxins: botulinum neurotoxin (BoNT) serotype B and a novel BoNT reported a

100 c method for the detection of four botulinum neurotoxin (BoNT) serotypes responsible for human botuli

101 simultaneous on-site detection of botulinum neurotoxin (BoNT) types A, B, and E in complex matrixes,

102 ny of the seven known serotypes of botulinum neurotoxin (BoNT), all of which disrupt synaptic transmi

103 fatal paralytic disease caused by botulinum neurotoxin (BoNT).

104 east one of the seven serotypes of botulinum neurotoxin (BoNT/A-G).

105 Botulinum neurotoxins (BoNT) are the most potent toxins known and

106 Botulinum neurotoxins (BoNT/A-G) act by blocking synaptic vesicle

107 mics approach, we report here that all three neurotoxins, BoNT/A2, /F4, and /F5, are produced by C. b

108 Botulinum neurotoxins (BoNTs) and tetanus neurotoxin (TeNT) are th

109 neurotoxins (CNTs), which include botulinum neurotoxins (BoNTs) and tetanus neurotoxin (TeNT), are t

110 Botulinum neurotoxins (BoNTs) and tetanus toxin (TeNT) are the mos

111 Botulinum neurotoxins (BoNTs) are a family of bacterial toxins wit

112 Botulium neurotoxins (BoNTs) are among the most lethal toxins kno

113 Botulinum neurotoxins (BoNTs) are among the most poisonous biologi

114 Botulinum neurotoxins (BoNTs) are highly potent bacterial proteins

115 Botulinum neurotoxins (BoNTs) are highly potent toxins that cleave

116 Botulinum neurotoxins (BoNTs) are produced by various species of c

117 Botulinum neurotoxins (BoNTs) are synthesized by Clostridium botul

118 Botulinum neurotoxins (BoNTs) are the most toxic proteins for huma

119 Botulinum neurotoxins (BoNTs) are the most toxic substances known.

120 Botulinum neurotoxins (BoNTs) are used in a wide variety of medica

121 How botulinum neurotoxins (BoNTs) cross the host intestinal epithelial

122 Botulinum neurotoxins (BoNTs) form a large class of potent and dea

123 Botulinum neurotoxins (BoNTs) possess unique specificity for nerve

124 Botulinum neurotoxins (BoNTs) produced by Clostridium botulinum ar

125 Clostridium botulinum produces botulinum neurotoxins (BoNTs), highly potent substances responsibl

126 Botulinum neurotoxins (BoNTs), the most potent toxins known, are p

127 calcium-dependent and inhibited by botulinum neurotoxin C, demonstrating the involvement of SNARE-dep

128 not when syntaxin-1 is cleaved by botulinum neurotoxin C.

129 The interaction between sublethal doses of a neurotoxin, clothianidin, and the ectoparasite, Varroa d

130 botulinum neurotoxin (BoNT) are clostridial neurotoxins (CNTs) responsible for the paralytic disease

131 Clostridial neurotoxins (CNTs), which include botulinum neurotoxins

132 convert the inactive prodrug Daun02 into the neurotoxin daunorubicin.

133 inals exposed to spider or snake presynaptic neurotoxins degenerate as a result of calcium overload a

134 ne-coated nanoparticle (RBCNP) with a unique neurotoxin-derived targeting moiety.

135 pneumonia indicated that endothelium-derived neurotoxins disrupted the postsynaptic synaptic response

136 Zalophus californianus) exposed to the algal neurotoxin domoic acid are treated in veterinary rehabil

137 was developed for the detection of botulinum neurotoxin-E (BoNT/E).

138 tly reduced the levels of eosinophil-derived neurotoxin (EDN) in those infected at baseline.

139 leukotrienes (CysLT), and eosinophil-derived neurotoxin (EDN) release.

140 ilia and IL-5, IL-13, and eosinophil-derived neurotoxin (EDN), which stayed consistent after 6 weeks.

141 r basic protein [MBP] and eosinophil-derived neurotoxin [EDN]; Spearman's r = 0.3090 and 0.3778, resp

142 Human LYNX1, belonging to the Ly6/neurotoxin family of three-finger proteins, is membrane-

143 Luteovirid coat protein-insect neurotoxin fusions represent a promising strategy for tr

144 lostridial organism containing more than two neurotoxin gene clusters.

145 Clostridium botulinum strain Af84 has three neurotoxin gene clusters: bont/A2, bont/F4, and bont/F5.

146 neurotoxins, including tetanus and botulinum neurotoxins, generally target vertebrates.

147 The neurotoxin genes were then deleted independently in the

148 xin fulfills a plethora of functions such as neurotoxin, gliotoxin, and proinflammatory mediator, and

149 ghly toxic metal traditionally regarded as a neurotoxin, has been recently suggested as a potential c

150 Botulinum neurotoxins have remarkable persistence (~weeks to month

151 ethylation, however, SAM is converted to the neurotoxin homocysteine and must be excreted or drawn ba

152 e versuta (Blue Mountains funnel-web spider) neurotoxin (Hvt) and onion leaf lectin, in tobacco (Nico

153 MeHg as a neurotoxin impacts on the human central nervous systems

154 ound that expression of four insect specific neurotoxins improved the efficacy of M. acridum against

155 For facial injections of neurotoxin in saline, 30-gauge needles were associated w

156 first time that, during exposure to an HIV-1 neurotoxin in vivo, alteration of GluN2B-containing NMDA

157 f amyloid-beta (Abeta) oligomers, AD-related neurotoxins, in the brains of rats and adult nonhuman pr

158 requently targeted by deadly gating-modifier neurotoxins, including tarantula toxins, which trap the

159 Clostridial neurotoxins, including tetanus and botulinum neurotoxins

160 notoxin ImI and a chimeric Naja oxiana alpha-neurotoxin indicating that the major role in alpha-Ctx b

161 prague-Dawley) with histologically confirmed neurotoxin-induced bilateral (BGCX, n = 13), or right (R

162 fed on these fusion proteins showed signs of neurotoxin-induced paralysis.

163 nd PLD1 positively control fusion of tetanus neurotoxin insensitive vesicle-associated membrane prote

164 cision placement of agents (e.g., tracers or neurotoxins) into small brain regions of the infant and

165 peptide (AbetaOs) are thought to be proximal neurotoxins involved in early neuronal oxidative stress

166 Botulinum neurotoxin is considered as one of the most toxic food-b

167 e, convenient, and rapid assay for botulinum neurotoxins is therefore highly desirable for addressing

168 though its contamination by mercury, a known neurotoxin, is a growing concern.

169 Tetrodotoxin (TTX), a small molecular weight neurotoxin, is responsible for poisoning events that tra

170 tamate analogs, like the classic excitotoxic neurotoxins kainic acid, domoic acid, and NMDA; the ther

171 Domoic acid (DA) is a naturally occurring neurotoxin known to harm marine animals.

172 manganese and zinc, and higher uptake of the neurotoxin lead.

173 d fewer striatal connections 7 weeks after a neurotoxin lesion.

174 on (ie, high pretreatment eosinophil-derived neurotoxin levels or blood eosinophil counts).

175 Potent neurotoxins like tetrodotoxin (TTX) and saxitoxin (STX)

176 Glycosylphosphatidylinositol-anchored neurotoxin-like receptor binding proteins, such as lynx

177 The neurotoxin-like region of the rabies virus glycoprotein

178 A neurotoxin-like sequence motif on the receptor-binding d

179 y some other three-finger toxins, long alpha-neurotoxin Ls III and nonconventional toxin WTX.

180 ains 7, 8, and 9 of the highly potent marine neurotoxin maitotoxin (1), the largest secondary metabol

181 suggesting that the accumulation of uraemic neurotoxins may be more important than disturbed haemody

182 streamwater concentrations and export of the neurotoxin methyl mercury (MeHg) to freshwater ecosystem

183 t receives gestational exposure (E17) to the neurotoxin methylazoxymethanol (MAM).

184 s with some of the highest concentrations of neurotoxin methylmercury (MeHg) among marine top predato

185 Microbial production of the bioaccumulative neurotoxin methylmercury (MeHg) is stimulated in newly f

186 f the limiting steps in the formation of the neurotoxin methylmercury (MeHg).

187 ributes to the bioaccumulation of the potent neurotoxin methylmercury in the marine food web.

188 We first took advantage of an in vitro neurotoxin model of Parkinson's disease and found that t

189 LTCC blockers were neuroprotective in mouse neurotoxin models of PD, and isradipine is currently und

190 gainst anatoxin-a (ATX), the smallest potent neurotoxin (Mol.

191 se species contain the highest levels of the neurotoxin monomethylmercury (MMHg) and therefore presen

192 eria that produce the potent bioaccumulative neurotoxin monomethylmercury remains one of the greatest

193 basal ganglia, and with the discovery of the neurotoxin MPTP a monkey model of PD had been developed.

194 in different lineages to function as potent neurotoxins, myotoxins, or hemotoxins.

195 nd female P301S tau transgenic mice with the neurotoxin N-(2-chloroethyl)-N-ethyl-bromobenzylamine (D

196 Monomethylmercury (MMHg) is a neurotoxin of concern in the Canadian Arctic due to its

197 Insect neurotoxins offer an alternative to chemical insecticide

198 we studied the effect of this environmental neurotoxin on PP2A activity and tau hyperphosphorylation

199 < 0.001, r = 0.7353] and eosinophil-derived neurotoxin [p < 0.01, r = 0.7059]).

200 ll protection from degeneration in vivo in a neurotoxin Parkinson's mouse model.

201 Annonaceous acetogenins (AAGs) are neurotoxins possibly responsible for atypical Parkinsoni

202 Here we describe the purification of a neurotoxin precursor processing protease from the venom

203 y of the protease in propeptide removal from neurotoxin precursors by cleavage C-terminal of the PQM.

204 es mimicking the predicted cleavage sites of neurotoxin precursors.

205 ns, the genes of a specialized heterodimeric neurotoxin predate the origin of rattlesnakes and were p

206 Domoic acid is a potent neurotoxin produced by certain marine microalgae that ca

207 Methylmercury (MeHg) is a bioaccumulative neurotoxin produced by certain sulfate-reducing bacteria

208 The HIV-1 Tat protein is a potent neurotoxin produced during HAND that induces activation

209 Methylmercury is a potent neurotoxin produced in natural environments from inorgan

210 Outbreaks are caused by bird ingestion of neurotoxins produced by Clostridium botulinum, a spore-f

211 e first report of three enzymatically active neurotoxins produced in a single strain of Clostridium b

212 The highly poisonous botulinum neurotoxins, produced by the bacterium Clostridium botul

213 epod Calanus finmarchicus co-occurs with the neurotoxin-producing dinoflagellate, Alexandrium fundyen

214 this paper we present a scheme for modelling neurotoxin production in C. botulinum Group I type A1, b

215 ship between HIV replication, HO-1 loss, and neurotoxin production in MDM that likely reflects proces

216 crophage HO-1 deficiency, and the associated neurotoxin production, is a conserved feature of infecti

217 does not prevent HO-1 loss or the associated neurotoxin production.

218 red to detect the trace amount of endogenous neurotoxin (QA).

219 be for the selective detection of endogenous neurotoxin quinolinic acid (QA) whose elevated level in

220 The neurotoxin quinolinic acid may impair blood-brain barrie

221 ration is induced by some animal presynaptic neurotoxins, representing an appropriate and controlled

222 icardial application of a selective afferent neurotoxin, resiniferatoxin, selectively lowered diastol

223 errence against predation, while it achieves neurotoxin resistance through point mutations in sodium

224 r muscle, sophisticated eyes, and remarkable neurotoxin resistance.

225 Pseudomonas aeruginosa exotoxin A, Botulinum neurotoxin, ricin, and Zika virus.

226 cleases (RNases), namely, eosinophil-derived neurotoxin (RNS2) and eosinophil cationic protein (RNS3)

227 zation of CLC/Gal-10 with eosinophil-derived neurotoxin/RNS2 and CD63.

228 pression changes induced by the Parkinsonian neurotoxin rotenone and opposed by those induced by clio

229 AR by epicardial application of the afferent neurotoxin, RTX, selectively lowered diastolic blood pre

230 us animals such as scorpions produce diverse neurotoxins selected to hit targets in the nervous syste

231 Botulinum neurotoxin serotype A (BoNT/A) causes a debilitating and

232 (4,7-ACQ) based inhibitors of the botulinum neurotoxin serotype A (BoNT/A) light chain were synthesi

233 says for colorimetric detection of botulinum neurotoxin serotype A light chain (BoLcA).

234 analogues of dual antimalarial and botulinum neurotoxin serotype A light chain (BoNT/A LC) inhibitor

235 gosaccharide GD1a can associate to botulinum neurotoxin serotype A when expressed as individual trisa

236 ate minimal binding epitope of the botulinum neurotoxin serotype A.

237 ocumented or suspected exposure to botulinum neurotoxin serotypes A-G in adults and pediatric patient

238 Stichodactyla helianthus neurotoxin (ShK) is an immunomodulatory peptide currentl

239 pontaneous recovery after stroke, as tetanus neurotoxin silencing specifically of the SVZ-derived neu

240 d and functionally characterized to date are neurotoxins specifically targeted to receptors, ion chan

241 agent vincristine, antimalarial quinine and neurotoxin strychnine, are synthesized in several differ

242 orescent recognition agent for the botulinum neurotoxin subtype A (BoNT/A) using the virtual screenin

243 work showed that cellular stress created by neurotoxins such as MPTP and 6-hydroxydopamine can upreg

244 oxicity is indirect, resulting from released neurotoxins such as the HIV-1 protein transactivator of

245 enotype appears to be plastic as exposure to neurotoxins, such as 6-OHDA or MPTP, that model certain

246 Tetanus neurotoxin (TeNT) and botulinum neurotoxin (BoNT) are cl

247 Botulinum neurotoxins (BoNTs) and tetanus neurotoxin (TeNT) are the most potent toxins known and c

248 Tetanus neurotoxin (TeNT) causes neuroparalytic disease by enter

249 on, which was enhanced by expressing tetanus neurotoxin (TeNT) in the ipsilateral axon, to prevent He

250 Tetanus neurotoxin (TeNT) is among the most poisonous substances

251 AREs (synaptobrevins/VAMP1/2/3 using tetanus neurotoxin (TeNT), also in TI-VAMP/VAMP7 knock-out (KO)

252 de botulinum neurotoxins (BoNTs) and tetanus neurotoxin (TeNT), are the most potent toxins known to s

253 ignificant capacity to store psychosine, the neurotoxin that accumulates in Krabbe disease.

254 Newts are defended by tetrodotoxin (TTX), a neurotoxin that binds to voltage-gated sodium channels (

255 elevated loadings of methylmercury (MeHg; a neurotoxin that biomagnifies through foodwebs) due to oi

256 Mercury (Hg) is a neurotoxin that can be particularly harmful to top preda

257 eurotoxin type A (BoNT/A) is a highly potent neurotoxin that elicits flaccid paralysis by enzymatic c

258 develop TLE after exposure to domoic acid, a neurotoxin that enters the marine food chain during harm

259 with 1-methyl-4-phenylpyridinium (MPP(+)), a neurotoxin that inhibits complex I of electron transport

260 Methylmercury (MeHg) is a potent neurotoxin that is biomagnified approximately 1-10 milli

261 Ammonia is a potent neurotoxin that is detoxified mainly by the urea cycle i

262 rum, by identifying PMP1, a clostridial-like neurotoxin that selectively targets anopheline mosquitoe

263 ation of an NPY-conjugated saporin ribosomal neurotoxin that spares the central terminals of primary

264 llate produces brevetoxins, which are potent neurotoxins that cause neurotoxic shellfish poisoning an

265 id screening of tetrodotoxins (TTXs), potent neurotoxins that constitute a food safety hazard when pr

266 Brevetoxins (BTXs) are very potent marine neurotoxins that increased in geographical distribution

267 ly beta-carbolines and isoquinolines, act as neurotoxins that induce PD or enhance progression of the

268 Neurotoxins that mimic Parkinson's disease increased Cav

269 Neurotoxins that mimic Parkinson's disease target TRPC1

270 ellate Karenia brevis, which produces potent neurotoxins that negatively impact coastal marine ecosys

271 alpha-Conotoxins are disulfide-rich peptide neurotoxins that selectively inhibit neuronal nicotinic

272 Harmful algal blooms (HABs) produce potent neurotoxins that threaten human health, but current regu

273 t North American rattlesnakes do not produce neurotoxins, the genes of a specialized heterodimeric ne

274 (methamphetamine and fentanyl), anesthetics, neurotoxins, the pesticide paraquat, and heparin anti-co

275 etwork excitability in the presence of HIV-1 neurotoxins; these changes may inform the development of

276 sensitive detection of Clostridium botulinum Neurotoxin Type A (BoNT/A) in complex, real-world media.

277 Botulinum neurotoxin type A (BoNT/A) is a highly potent neurotoxin

278 012 is a recombinant derivative of Botulinum neurotoxin Type A (BoNT/A).

279 ent with infant botulism, produced botulinum neurotoxin type B (BoNT/B) and another BoNT that, by use

280 Botulinum neurotoxin type B (BoNT/B) recognizes nerve terminals by

281 The botulinum neurotoxin type D is one of seven highly potent toxins p

282 Botulinum neurotoxin type E (BoNT/E) is a member of a family of se

283 ent was prevented by expression of botulinum neurotoxin type E.

284 duces the recently described novel botulinum neurotoxin type H (BoNT/H).

285 e of 62 (SD 22) treatments of 70.2 (SD 20.8) neurotoxin units.

286 ctionalization occurred in snake venom alpha-neurotoxins upon loss of another pair of the plesiotypic

287 d by examining the enzymatic activity of the neurotoxins upon peptide substrates, which mimic the tox

288 tect against dopaminergic deficits caused by neurotoxins via increased neurogenesis in the subventric

289 The enzymatic activity of all three neurotoxins was assessed by examining the enzymatic acti

290 aightforward detection between OP and non-OP neurotoxins was successfully achieved with cyclic voltam

291 Using a selective neurotoxin, we also demonstrate differential drive of th

292 and antagonist responses nicotine and known neurotoxins were detected from tobacco extract and snake

293 rticular interest as methylmercury (MeHg), a neurotoxin which bioaccumulates through foodwebs, can re

294 various species of clostridia and are potent neurotoxins which cause the disease botulism, by cleavin

295 mercury (MeHg(+) ) is one of the most potent neurotoxins, which damages the brain and nervous system

296 Botulinum and tetanus neurotoxins, which specifically proteolyze vesicle fusio

297 and epitope, and these compounds bind to the neurotoxin with a high degree of predisposition but with

298 is the first discovery of a single botulinum neurotoxin with BoNT/A antigenicity and BoNT/F light cha

299 supernatants and tested each immune-captured neurotoxin with full-length substrates vesicle-associate

300 Methylmercury (MeHg) is an environmental neurotoxin with human exposure mainly from dietary intak