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1 the kinase-active Trk receptors and the p75 neurotrophin receptor.
2 ke receptor superfamilies, including the p75 neurotrophin receptor.
3 omponent of this receptor complex is the p75 neurotrophin receptor.
4 receptor tyrosine kinases and the shared p75 neurotrophin receptor.
5 similar gamma-secretase cleavage is the p75 neurotrophin receptor.
6 ate with the intracellular domain of the p75 neurotrophin receptor.
7 ota PKC.IRAK complex is recruited to the p75 neurotrophin receptor.
8 anism, supported by up-regulation of the p75 neurotrophin receptor.
9 actions of BDNF are mediated through the p75 neurotrophin receptor.
10 e induced by selective activation of the p75 neurotrophin receptor.
11 Schwann cell death via engagement of the p75 neurotrophin receptor.
12 or cell death decisions mediated by the p75 neurotrophin receptor.
13 tracellular neurotrophin binding site of p75 neurotrophin receptor.
14 f differentiation markers, and activation of neurotrophin receptors.
15 synthetic derivative LIGA20 activate various neurotrophin receptors.
16 small molecule agonists to transactivate Trk neurotrophin receptors.
17 S can physically associate with TrkA and p75 neurotrophin receptors.
18 least in part to differential trafficking of neurotrophin receptors.
22 udies provide a new reagent for altering p75 neurotrophin receptor actions after injury and suggest t
23 th factor (NGF) binding to both p75 and TrkA neurotrophin receptors activates the transcription facto
26 egulation of neurotrophins and their cognate neurotrophin receptors among other classes of transcript
27 ia the tyrosine receptor kinase B (TrkB)/p75 neurotrophin receptor and Fyn kinase in transfected cell
30 the cell death mediator p75(NTR) (the common neurotrophin receptor), and its interaction with proapop
31 or induced apoptosis in cells expressing p75 neurotrophin receptor, and enhances neurite outgrowth in
32 d trkC-IgG) were used to block activation of neurotrophin receptors, and AADH-CNTF was used to antago
33 was blocked by exposure to the high-affinity neurotrophin receptor antagonist K252a, or an antagonist
35 lipid rafts, little is known about how these neurotrophin receptors are directed there or how localiz
43 es binding of pro-nerve growth factor to p75 neurotrophin receptor, blocks pro-nerve growth factor in
44 growth factor (NGF) in complex with the p75 neurotrophin receptor but is distinct from that of micro
45 osteoprotegerin, FOXC2 and FOXF2, BMP-2, p75 neurotrophin receptor, caspase-11, guanylate-binding pro
48 library for genes affecting the dynamics of neurotrophin receptor-containing endosomes in motor neur
50 ssion of TrkC, a member of the Trk family of neurotrophin receptors, could drive tumorigenesis, invas
51 closely related to NRAGE, which mediates p75 neurotrophin receptor-dependent apoptosis, and necdin, w
52 of dynamin1 is a critical event coordinating neurotrophin receptor endocytosis and axonal growth.
53 kB (tropomyosin kinase receptor B), the main neurotrophin receptor expressed by neurons of the centra
54 lus propofol applications at the peak of p75 neurotrophin receptor expression after experimental trau
55 ricted to the developing nervous system when neurotrophin receptor expression peaks, indicate that BI
57 se is the lack of NO, which up-regulated p75 neurotrophin receptor expression, a receptor required fo
58 creased raft formation, neurotransmitter and neurotrophin receptor expression, NMDA- and BDNF-mediate
59 developmental-like programs and increase p75 neurotrophin receptor expression, probably to foster rep
60 tyrosine-related kinase B (TrkB) p75NTR (p75 neurotrophin receptor) facilitates stabilization of the
61 ceptor B (trkB) and a truncated form of this neurotrophin receptor, favoring the inactive form throug
62 hat Toll paralogs unrelated to the mammalian neurotrophin receptors function as neurotrophin receptor
63 S-HGGs, with recurrent fusions involving the neurotrophin receptor genes NTRK1, NTRK2 and NTRK3 in 40
65 tly, a closely related gene to p75NTR called neurotrophin receptor homolog-2 (NRH2) was identified; h
66 5 kDa neurotrophin receptor (p75NTR) and two neurotrophin receptor homologs (NRH1, NRH2) constitute a
68 ntrast, optical density for low-affinity p75 neurotrophin receptor immunoreactivity in the VLDB did n
69 myosin-related kinase B receptor (TrkB) is a neurotrophin receptor important for the synaptic plastic
74 We found that TrkB is the most prominent neurotrophin receptor in the mouse SVZ, but only the tru
75 ence for either ChAT or the low-affinity p75 neurotrophin receptor in the nucleus basalis Meynert fai
78 -stimulating factor (M-CSF), the M-CSFR, and neurotrophin receptors in the NMDA-treated slices, as de
80 t-derived NGF promotes expression of the p75 neurotrophin receptor, in turn causing a reduction in th
82 functional interaction between TRAF6 and the neurotrophin receptor interacting factor (NRIF), two pro
88 aline residue at position 264 in the rat p75 neurotrophin receptor is necessary for the ability of p7
91 dings indicate that intracellular sorting of neurotrophin receptors is critical for postnatal neuroge
93 e tropomyosin-related kinase (Trk) family of neurotrophin receptors, is implicated in the growth and
96 y signals through the same Nogo receptor/p75 neurotrophin receptor/LINGO-1 (NgR1/p75/LINGO-1) complex
100 is and recent evidence suggests that the p75 neurotrophin receptor (NTR) contributes significantly to
102 nt on the proper subcellular localization of neurotrophin receptor (NTR) to plasmalemmal signaling mi
103 while down-regulating the expression of p75 neurotrophin receptor (NTR), phospho-JNK, and Bcl-2-asso
104 rid library with the death domain of the p75 neurotrophin receptor (NTR), we identified the Sall2 tra
108 compound, EVT901, which interferes with p75 neurotrophin receptor oligomerization through direct int
110 tivity for pro-nerve growth factor (proNGF), neurotrophin receptor p75 (p75(NTR)), and sortilin in th
111 hese effects are mediated by presynaptic pan-neurotrophin receptor p75 (p75(NTR)), the pro-BDNF recep
118 lines of in vitro evidence suggest that the neurotrophin receptor p75 mediates or exacerbates Abeta-
120 induce apoptosis in neuronal cells, via the neurotrophin receptor p75(NTR) and the sortilin receptor
122 ed a marked upregulation of the proapoptotic neurotrophin receptor p75(NTR) in CA1, evident at 48 hr.
123 in PC-3 cells and siRNA directed against the neurotrophin receptor p75(NTR) in post-mitotic cultures
127 ases, may interact with the proapoptotic pan-neurotrophin receptor p75(NTR) to induce neuronal cytosk
128 kinase TrkA (also called NTRK1), the common neurotrophin receptor p75(NTR), and the proneurotrophin
129 how that the transmembrane domain of the pan-neurotrophin receptor p75(NTR), best known for regulatin
130 ability of SorCS2 to form complexes with the neurotrophin receptor p75(NTR), required for pro-brain-d
131 tion of saporin linked to an antibody to the neurotrophin receptor p75(NTR), which eliminates cells e
139 ll number and the number of cells expressing neurotrophin receptors p75(NGFR) and trkA were assessed.
140 d immunoprecipitation with antibodies to the neurotrophin receptors p75, trkA, trkB, and trkC showed
143 TAp73 is a transcriptional activator of p75 neurotrophin receptor (p75(NTR)) and that p75(NTR) mRNA
146 trophic factor (BDNF)-activated TrkB and p75 neurotrophin receptor (p75(NTR)) by disrupting the endos
147 ole in Alzheimer's disease (AD), and the p75 neurotrophin receptor (p75(NTR)) has been implicated in
156 rve growth factor (NGF) signaling by the p75 neurotrophin receptor (p75(NTR)) is critical for neurona
157 distinct structural determinants in the p75 neurotrophin receptor (p75(NTR)) is crucial for the iden
163 be initiated by activation of either the p75 neurotrophin receptor (p75(NTR)) or the more selective t
164 xes with LINGO-1 and either the low-affinity neurotrophin receptor (p75(NTR)) or TROY to initiate gro
166 ular signaling networks regulated by the p75 neurotrophin receptor (p75(NTR)) substantially overlap w
168 ron loss, distal axonal degeneration and p75 neurotrophin receptor (p75(NTR)) upregulation in the per
169 Strikingly, mutant male mice lacking the p75 neurotrophin receptor (p75(NTR)) were resistant to the d
170 tingly, mutant male mice that lacked the p75 neurotrophin receptor (p75(NTR)) were seen to be resista
171 uctures of complexes formed by the DD of p75 neurotrophin receptor (p75(NTR)) with RhoGDI, for activa
172 e de novo expression of the low-affinity p75 neurotrophin receptor (p75(NTR)), a gene that plays crit
175 mined the expression of the low affinity p75 neurotrophin receptor (p75(NTR)), an excellent marker of
176 This produced a substantial loss of both p75 neurotrophin receptor (p75(NTR))-positive and choline ac
181 receptor tyrosine kinases (Trk) and the pan-neurotrophin receptor (p75) to regulate complex developm
183 osin-related kinase receptors (Trks) and p75 neurotrophin receptors (p75) compete to regulate surviva
185 In recent studies, we have identified the neurotrophin receptor, p75(NTR), as a mediator of apopto
186 We discovered that the expression of the neurotrophin receptor p75NTR in PV cells inhibits the ma
193 nase receptor TrkA, together with the common neurotrophin receptor p75NTR; both of which bind nerve g
194 neurotrophins bind with high affinity to p75 neurotrophin receptor (p75NTR) and lack the capacity to
198 t with antisense oligonucleotides to the p75 neurotrophin receptor (p75ntr) decreased basal survival
199 t of the sympathetic nervous system, the p75 neurotrophin receptor (p75NTR) has a dual function: prom
200 Here, we investigate the involvement of p75 neurotrophin receptor (p75NTR) in Abeta-treated human ne
202 ur goal was to determine the role of the p75 neurotrophin receptor (p75NTR) in the loss of islet symp
203 myelin-associated glycoprotein recruited p75 neurotrophin receptor (p75NTR) into a complex with LRP1
208 Plasticity was rescued by inhibiting p75 neurotrophin receptor (p75NTR) signaling or its downstre
211 drinking produces a mobilization of DLS p75 neurotrophin receptor (p75NTR), whose activities oppose
218 nchymal cells expressing both desmin and p75 neurotrophin receptor (p75NTR): HSCs in the liver parenc
219 ng cells (BTICs) and show that BTICs express neurotrophin receptors (p75NTR, TrkA, TrkB, and TrkC) an
220 re, we demonstrate that mice lacking the p75 neurotrophin receptor, p75NTR, decrease their feeding an
221 rats by the recruitment of the low-affinity neurotrophin receptor, p75NTR, whose activities opposes
222 ed a mouse model with a mutation in the TrkA neurotrophin receptor (P782S) that results in reduced ub
224 same set of transcription factors from a p75 neurotrophin receptor peptide (p75NTRp)-tagged adenoviru
225 indicate that the ubiquitination of the TrkA neurotrophin receptor plays a critical role in NGF-media
228 fact that blockade of tyrosine kinase (Trk) neurotrophin receptors reduces basal GABRA4 promoter act
230 tyrosine receptor kinase A (TrkA) and TrkC, neurotrophin receptors required by DRG sensory neuron de
232 chrome (DrBphP-PCM) to the kinase domains of neurotrophin receptors resulted in opto-RTKs controlled
234 ng trkA, trkB, and trkC, the identity of the neurotrophin receptor(s) undergoing phosphorylation was
235 t of NRAGE, a MAGE protein that mediates p75 neurotrophin receptor signaling and neuronal apoptosis.
237 sults revealed new functions for proBDNF-p75 neurotrophin receptor signaling pathway in the control o
238 dopamine D1 receptors can be coupled to the neurotrophin receptor signaling to mediate the effects o
240 re, we demonstrate that EVT901 abrogates p75 neurotrophin receptor signalling by other ligands, such
243 cate that UCH-L1 is important for regulating neurotrophin receptor sorting to signaling endosomes and
244 gp120 were blocked by inhibitors of the p75 neurotrophin receptor, suggesting that proBDNF and gp120
245 hibition of the cell death domain of the p75 neurotrophin receptor (TAT-Pep5) and in mice lacking the
247 rocessing of synaptic vesicle components and neurotrophin receptors, the mechanism giving access to t
248 e, nicotinic acetylcholine receptor, and p75 neurotrophin receptor), thus demonstrating that pseudoty
249 dence for the CB1 receptor coupling the TrkB neurotrophin receptor to an axonal growth response in th
250 r-3 directly associates and recruits the p75 neurotrophin receptor to the axon-glial junction, formin
251 ility to redirect the apically localized P75 neurotrophin receptor to the basolateral membrane domain
253 hotyrosine immunoprecipitates identified the neurotrophin receptor TrkA (molecular weight approximate
255 that LRP1 activation could phosphorylate the neurotrophin receptor TrkA in PC12 cells and increase ne
256 on axonal transport of mitochondria and the neurotrophin receptor TrkA, cargoes that are critical fo
258 ss sensory neuron-associated markers such as neurotrophin receptors TrkA, TrkB, TrkC, and RET and the
261 rs of the neural crest and expression of the neurotrophin receptor TrkB and its ligand, brain-derived
262 Interestingly, APPL1-endosomes transport the neurotrophin receptor TrkB and mediate retrograde axonal
263 endritically localized mRNA encoding for the neurotrophin receptor TrkB has important ramifications f
264 roitinase and fluoxetine are mediated by the neurotrophin receptor TRKB in parvalbumin-containing (PV
266 -ERK-CREB-BDNF pathway as pre-treatment with neurotrophin receptor TrkB inhibitor ANA-12 and MEK inhi
267 isual cortical neurons in young rodents, the neurotrophin receptor TrkB is associated with PSD-95.
268 is study, we show that the expression of the neurotrophin receptor TrkB is induced on astrocytes in w
273 sion of extracellularly tagged transmembrane neurotrophin receptors TrkB and p75 on transfected neuro
275 om fresh human malignant gliomas express the neurotrophin receptors TrkB and TrkC, not TrkA, and they
278 ell surface signaling receptors, such as the neurotrophin receptor, TrkB, have emerged as potential t
280 ed inner ear sensory neurons fail to express neurotrophin receptors, TrkB and TrkC, suggesting that t
285 During retrograde signaling, endocytosed neurotrophin receptors (Trks) activate the extracellular
286 broblast growth factor receptors (FGFRs) and neurotrophin receptors (TRKs) through their N-terminal p
295 assays with cysteine-rich domains-fused p75 neurotrophin receptor, we confirmed that EVT901 interfer
296 receptor agonist SKF38393, we found that Trk neurotrophin receptors were activated in embryonic day 1
298 involved in ectodomain shedding of p75NTR, a neurotrophin receptor with critical roles in neuronal di
299 and increasing the co-localisation of these neurotrophin receptors with retromer-associated sorting
300 -tagged raft-independent protein (the 75-kDa neurotrophin receptor; YFP-p75) was efficient even in th