ライフサイエンスコーパス: newborn

1 imately 60% of full-term and 80% of pre-term newborns).

2 rrest and hypoxic-ischemic encephalopathy of newborns).

3 ndicating a better physical condition of the newborn.

4 prevents haemolytic disease of the fetus and newborn.

5 sent in the placenta and 6% was found in the newborn.

6 mollients to try and prevent eczema in their newborn.

7 ses women to the risk of having a macrosomic newborn.

8 th higher epigenetic age acceleration in the newborn.

9 nal intestinal microbiota of both mother and newborn.

10 ed with cardiovascular health markers in the newborn.

11 others and compared them with those of their newborns.

12 d to better protect pregnant women and their newborns.

13 f general anesthesia in 47 MRI studies in 42 newborns.

14 y after birth and thus prevent blood loss in newborns.

15 systems, including transplant recipients and newborns.

16 n of 250 S. capitis isolates from adults and newborns.

17 r mitochondrial respiration compared to male newborns.

18 improved micronutrient status of Bangladeshi newborns.

19 s, but not with mitochondrial respiration in newborns.

20 irus Abs when infected as adults, but not as newborns.

21 ewborns die at three times the rate of White newborns.

22 irus is among the most serious infections of newborns.

23 odeficiency (SCID) that usually manifests in newborns.

24 route for establishing the gut microbiome in newborns.

25 al micronutrient status in rural Bangladeshi newborns.

26 - 0.32 mSv for an injected dose of 20 MBq in newborns.

27 source of inoculum in the gut microbiome of newborns.

28 se at least 1 child born into the study as a newborn, 1 other child, a parent, and a grandparent.

29 y discharge (ED) on healthy mothers and term newborns after vaginal deliveries (VD) is still inconclu

30 The effect of HBV vaccination of newborns, already seen in young adults in some countries

31 Human newborns, already shortly after birth, preferentially or

32 rnal cortisol during pregnancy is related to newborn amygdala architecture and connectivity in a sexu

33 ese facilities, we assessed outcomes of 2938 newborn and fresh stillborn babies (1447 in the interven

34 Coverage indicators for newborn and maternal health care in exit surveys had low

35 ed convulsions (during normoglycemia) in one newborn and one death.

36 Starting at birth, the immune system of newborns and children encounters and is influenced by en

37 We enrolled healthy newborns and children with metabolic diseases or hearing

38 ses and overlap in pathways enriched both in newborns and children.

39 amples (also called fecal calprotectin) from newborns and during infancy, and their effects on develo

40 Recent evidence from human newborns and non-human animals has challenged the primar

41 of essential sexual, reproductive, maternal, newborn, and adolescent health interventions.

42 sed to track aid for reproductive, maternal, newborn, and child health (RMNCH).

43 g pregnancy protects both the mother and her newborn, and is safe.

44 rease the liveborn rate and survival time of newborns, and reduces perinatal brain injury in cases of

45 prospectively examined whether maternal and newborn anthropometric factors as reported by the mother

46 iotics supplementation on moderately preterm newborns' anthropometric development (weight-for-age and

47 About 1% of all newborns are affected by congenital heart disease (CHD).

48 ata from a substudy of platelet counts among newborns are also presented.

49 V) infection in children, and treatments for newborns are needed to abrogate infection or limit disea

50 Newborn astrocytes were derived from WT, Tnfalpha(-/-),

51 Newborn astrocytes were found all along the dorso-ventra

52 Despite the limited duration of newborns' attention, reliable frequency-tagged responses

53 l, 2016, 884 breastfeeding mothers and their newborn babies (HEU, n=471; HU, n=413) were enrolled int

54 etween July 14, 2017, and Sept 3, 2019, 3603 newborn babies and infants who presented for immunisatio

55 screened for sickle cell disease consecutive newborn babies and infants younger than 9 months who pre

56 al areas, in women compared with men, and in newborn babies compared with their mothers.

57 Although maternal antibodies protect newborn babies from infection(1,2), little is known abou

58 Currently, only 44% of newborn babies in low-income and middle-income countries

59 and verified the case notes of 1015 admitted newborn babies regarding antibiotic treatment.

60 We included women and their newborn babies who consented on admission to hospital.

61 Americas led to an unprecedented increase of newborn babies with developmental brain and eye abnormal

62 n the three testing methods in screening 313 newborn babies, with a specificity of 100% with HemoType

63 nd treat vitamin D deficiency, especially in newborn babies, women, and urban populations.

64 No neonatal asphyxia was observed in newborn babies.

65 an attractive sample type for CMV testing of newborns, because it is easier to collect than urine and

66 ds in simulated datasets and the Mothers and Newborns birth cohort of the Columbia Center for Childre

67 Every Newborn-BIRTH Indicators Research Tracking in Hospitals

68 iority trial involving 689 otherwise healthy newborns born at 35 weeks of gestation or later and iden

69 Newborns born between 30 to 38 completed weeks of gestat

70 lls (MDSCs) in the antimicrobial response in newborns, but the signals guiding their differentiation

71 es in the Young (TEDDY) study enrolled 8,676 newborns by screening of HLA-DR-DQ genotypes at six clin

72 al cells (EC) were isolated for RNA-Seq from newborn C57BL/6 mice treated with intraperitoneal lipopo

73 Newborn C57BL/6J (B6) mice were reared in quasi-monochro

74 We performed studies with newborn C57BL/6J wild-type and S100a9(-/-) mice (which a

75 capable of providing emergency obstetric and newborn care and capable of safe-guarding uncomplicated

76 ing the use of probiotics in routine preterm newborn care is lacking.

77 vement package for intrapartum and immediate newborn care on stillbirth and preterm neonatal survival

78 The immediate newborn care practice of placing the baby skin-to-skin w

79 education, maternal nutrition, maternal and newborn care, and reductions in fertility/reduced interp

80 ntral axis, counting however for only 11% of newborn cell population.

81 s also had reduced neuronal phenotype of SVZ newborn cells and increased striatal neuronal maturity.

82 lt hippocampal neurogenic niche, they remove newborn cells naturally undergoing apoptosis.

83 his was associated with decreased ability of newborn cells to mediate Ab-dependent cell killing.

84 During adult hippocampal neurogenesis, most newborn cells undergo apoptosis and are rapidly phagocyt

85 hter poles and prevents osmotic lysis of the newborn cells.

86 Maternal and newborn characteristics (health care setting and timefra

87 in permanent neurological disability for one newborn child every hour in the United States.

88 Gates Foundation; Partnership for Maternal, Newborn & Child Health.

89 in a broader embedded IR study on maternal, newborn, child, and adolescent health (MNCAH) program im

90 surement of effective coverage for maternal, newborn, child, and adolescent health and nutrition (MNC

91 ting and timeframe, maternal health factors, newborn clinical factors, obstetric history factors, soc

92 achieve 75 days of additional protection for newborns combined with a 75% coverage of their birth hou

93 the leading cause of perinatal mortality and newborn complications.

94 Notably, in human newborns, congenital heart defects strongly associate wi

95 lized upon a rare biomaterials collection of newborn CSF samples to conduct a quasi-prospective test

96 ct of breastfeeding initiation time on early newborn danger signs and severe illness.

97 In the spleen and circulation, newborn-derived Tregs expressed significantly higher lev

98 c mice to selectively manipulate activity of newborn DG neurons.

99 we examined the dynamics of AIS formation in newborn DGCs of young female adult C57BL/6J mice in vivo

100 In the United States, Black newborns die at three times the rate of White newborns.

101 Ric(EKO) newborns displayed an ichthyosis-like phenotype characte

102 Maternal preconception FAs are related to newborn DNA methylation of specific CpG sites, highlight

103 346) and 8 weeks of gestation (n = 374) with newborn DNA methylation.

104 of WB makes a massive screening difficult in newborns due to economic and technical limitations.

105 itochondrial bioenergetics of healthy mother-newborn dyads with varying degrees of CM.

106 In n = 102 healthy mother-newborn dyads, maternal peripheral blood mononuclear cel

107 re identified from a cohort of 38,233 mother-newborn dyads.

108 Treating biliary atresia in newborns earlier can delay or prevent the need for liver

109 to determine the early-life risk factors for newborn epigenetic aging, specifically maternal dietary

110 equencing (ES) for NBS in the North Carolina Newborn Exome Sequencing for Universal Screening (NC NEX

111 Antenatal MM supplementation increased newborn ferritin, 25(OH)D, and zinc, while maternal and

112 ritin, 25(OH)D, and zinc, while maternal and newborn folate, vitamins B-12, D, and E, zinc, and iodin

113 trometry (MS/MS) is currently used to screen newborns for a panel of rare inborn errors of metabolism

114 red maternal GBS-specific antibodies protect newborns from early-onset disease, yet their impact on G

115 usly rare clinical outcome, microcephaly, in newborns from mothers who were infected during pregnancy

116 Validated across two independent cohorts of newborns from West Africa and Australasia, a robust and

117 ormation directly or indirectly to cortex in newborn galagos.

118 cohol exposure (PAE) affects at least 10% of newborns globally and leads to the development of fetal

119 ferences in the distribution of resident and newborn granule cells along the dorso-ventral axis, divi

120 r of world's population), where a quarter of newborns have low birth weight.

121 health (34%, $5.4 billion), and maternal and newborn health (19%, $3.1 billion).

122 change included improvements in maternal and newborn health (27.8%), economic improvement (19.5%), in

123 educed open defecation (12.3%), maternal and newborn health care (11.5%), and economic improvement (9

124 I and maternal height, improved maternal and newborn health care, increased parental education, migra

125 rnicterus spectrum disorder (KSD) are common newborn health conditions in the developing world, contr

126 Maternal and newborn health receives considerably less funding than r

127 idwives to deliver high-quality maternal and newborn health services has been highlighted as a priori

128 of aid for reproductive health, maternal and newborn health, and child health at the global, donor, a

129 s the validity of indicators of maternal and newborn health-care coverage around the time of birth in

130 to have adverse effects on both mothers' and newborns' health.

131 MVI to HL and estimated the effectiveness of newborn hearing screening (HS) in identifying neonates w

132 .1555A>G or m.1494C>T variant passed routine newborn hearing screening, indicating that concurrent sc

133 RNA-seq on newborn hearts identifies differentially expressed genes

134 esence of autologous plasma neither improved newborn homeostatic extravasation nor shaped age-specifi

135 resting-state fMRI in the youngest sample of newborn humans tested to date, we indeed found that cort

136 (CMV) infections comprise a leading cause of newborn impairments worldwide and are pervasive concerns

137 Of 124 385 newborns in the screening study, 49.2% were female, 87.6

138 n (Illumina450K) in blood measured either in newborns, in prospective analyses, or cross-sectionally

139 a function of generation time, the number of newborn individuals and reproductive value.

140 oved to be remarkably effective in premature newborns, inducing a five-fold decrease of mortality in

141 ation and compressions fail to stabilize the newborn infant, appropriate routes of drug delivery duri

142 However, in terms of early care of the newborn infant, some of the topics addressed are relevan

143 c resonance imaging (MRI) in n = 292 healthy newborn infants (mean age at birth = 39.9 weeks) with re

144 The natural immunity of newborn infants and protective host immune mediators aga

145 valuation is relevant to more than 7 million newborn infants every year.

146 n of altered structural brain development in newborn infants with CHD compared to healthy controls us

147 arge intestine biopsies from 8 adults and 10 newborn infants without inflammatory bowel diseases (con

148 tending to breastfeed exclusively, and their newborn infants, were enrolled at delivery (n = 35 mothe

149 ccine-induced protective antibodies to their newborn infants.

150 TPB) deficiency is a fatal disease affecting newborn infants.

151 ) repertoires of peripheral blood T cells in newborns, infants, and young children from Europe and su

152 of Observational Studies in Epidemiology for Newborn Infection (STROBE-NI) checklist.

153 in humans; although it less commonly affects newborns, infection in this age group can be devastating

154 lications that, in turn, are associated with newborn infections.

155 Soon after birth, the newborn is exposed to the hostile environment of pathoge

156 this endogenous KAR activity locally in the newborn LA perturbed development of glutamatergic input

157 s embryo enters embryonic diapause until the newborn leaves the pouch 9 mo later.

158 liva swabs were collected prospectively from newborns <21 days old and tested by the Alethia assay ac

159 llapse seems independent of mutation (unlike newborn lung alveoli), selective proteome and possible l

160 ented significant protection in neurons from newborn male and female 4E-BP1-OE transgenic mice.

161 an important cause of invasive infection in newborns, maternal women, and older individuals with und

162 It is assumed that newborns may develop immune tolerance to milk-transmitte

163 d as T(R(VP2,VP4)) ) that when injected into newborn mice causes an obstructive jaundice phenotype wi

164 Nrf2-sufficient (wild type) newborn mice exposed to hyperoxia develop hypoalveolariz

165 Cardiomyocytes of newborn mice proliferate after injury or exposure to gro

166 ors interrupted ILC3 biogenesis and rendered newborn mice susceptible to pneumonia.

167 although the initial microbiota community of newborn mice was that obtained from the nursing mother,

168 ion after neonatal hyperoxic injury.Methods: Newborn mice were exposed to 75% O(2) for the first 7 da

169 d the main olfactory epithelium of adult and newborn mice.

170 y to an overproduction of layer V neurons in newborn mice.

171 use limited ZIKV replication and ameliorated newborn microcephaly in a murine model.

172 using a dynamic in vitro system in a preterm newborn model.

173 Our data suggests that newborn monocytes are intrinsically impaired in extravas

174 ctivated tissue constructs were colonized by newborn monocytes at the same frequency than adult monoc

175 Both CD16- and CD16+ newborn monocytes demonstrated lower adherence and extra

176 Newborn monocytes demonstrated significantly lower surfa

177 cursors, transplanted into the brains of the newborn mutants, were able to effectively compete and re

178 leads to impaired spine plasticity, reduced newborn neuron integration, and diminished precision of

179 nstrate a direct causal relationship between newborn neuronal activity and affective behavior.

180 in synaptic connections between hippocampal newborn neurons and excitatory input neurons.

181 exhibit hallmark fast rise and decay phases, newborn neurons display slow GPSCs with characteristics

182 bulb similarly to physiologically generated newborn neurons displaying a correct expression of molec

183 complexity of doublecortin-labeled maturing newborn neurons in the dentate gyrus subgranular zone, a

184 deficits in the migration and integration of newborn neurons in the functional circuitry of the DG.

185 Here we find that newborn neurons mature over many months in rats and may

186 g NSCs and BrdU+ neurons in the dDG, whereas newborn neurons of the vDG showed a prolonged differenti

187 pocampal slices to address how PVs signal to newborn neurons prior to the appearance of fast GPSCs.

188 , specifically by augmenting the survival of newborn neurons that directly support cognitive function

189 Formation of dendritic spines on newborn neurons was also impaired following demyelinatio

190 ed neurogenesis and synaptic connectivity of newborn neurons were reversed to normal levels during re

191 Suppressing excitability of newborn neurons without altering neurogenesis abolish th

192 ttern of adult NSCs, maturation time plan of newborn neurons, and ongoing gliogenesis.

193 In newborn neurons, we observe specific roles for LIC1 in t

194 n increased the number but not complexity of newborn neurons, while repeated Reelin infusions restore

195 transition and impacts on neurite growth of newborn neurons.

196 rse cell subtypes and areal specification of newborn neurons.

197 s, but persists for 2-3 d at lower levels in newborn neurons.

198 In this study, we used a newborn nonhuman primate model to assess Treg population

199 hly represented in the T cell compartment of newborn nonhuman primates for all sites examined (i.e.,

200 h infection is usually asymptomatic or mild, newborns of infected mothers can display severe symptoms

201 screening of imprinting related disorders in newborns, offering several benefits compared to traditio

202 he latter is elicited de novo by placing the newborn on the ground for the first time.

203 iquely resistant to retroviruses acquired as newborns or as adults as they produce virus-neutralizing

204 rrest and hypoxic-ischemic encephalopathy of newborns) or intraoperative hypothermia.

205 some of these transcription factors, such as newborn ovary homeobox gene (NOBOX), are candidate genes

206 erapy has mitigated hemolytic disease of the newborn over the past half century, although breakthroug

207 accounting for absorbed iron present in the newborn (P < 0.001), and further increased by 7%, (from

208 These findings indicate that the newborn period is a critical window in pulmonary immunit

209 Serial regional brain growth from the newborn period to adolescence has not been described.

210 f Florida between 1992 and 2015 suggest that newborn-physician racial concordance is associated with

211 Eighteen newborn piglets (n = 6/group) with surfactant-deficient

212 spontaneously breathing surfactant-deficient newborn piglets to investigate the continuous positive a

213 Following hypoxia-ischemia, 20 newborn piglets were randomized to: (i) Cooling 1-13 h (

214 In newborn piglets with respiratory distress syndrome, the

215 s a common cause of bacteremia and sepsis in newborns, pregnant women, and immunocompromised patients

216 etinas, we used ATAC- and RNA-seq to compare newborn progenitors, immature MG (P8-P12), and mature MG

217 genitors for both generation and survival of newborn progeny.

218 that are more similar to those of full-term newborns, providing evidence for a beneficial effect of

219 elevated 7-DHC were observed in the brain of newborn pups 14 days after drug exposure.

220 l of BA, rhesus rotavirus (RRV) infection of newborn pups results in a cholangiopathy paralleling hum

221 lactating mice drives primary myelination in newborn pups via secretion in breast milk, whereas genet

222 d general anesthetic, which was delivered to newborn rabbits.

223 s the Vannucci model of unilateral HI in the newborn rat, is often greater than that reported from cl

224 sing neurons cultured from the hippocampi of newborn rats (both male and female), we observed signifi

225 nt at the extremes of life, especially among newborns, reflecting age-specific differences in immunit

226 ation in HIV infection, we randomly assigned newborn rhesus macaques to receive BCG vaccine or remain

227 AdV-A12, -A18, and -A31) can cause tumors in newborn rodents, with tumorigenicity related to the pres

228 ions associated with altered prenatal GCs in newborn's cord blood DNA.

229 via breast milk feeding, greatly assists the newborn's immune system.

230 Public health newborn screening (NBS) programs provide population-scal

231 Newborn screening (NBS) was established as a public heal

232 lood spots and fibroblast lysates that allow newborn screening and diagnosis of all MPS disorders exc

233 sufficiently simple and rapid to be used in newborn screening and diagnostic laboratories.

234 Newborn screening for CF has enabled earlier diagnosis,

235 Patients were identified through newborn screening for severe combined immunodeficiency u

236 t-of-care tests are reliable and accurate in newborn screening for sickle cell disease.

237 ur pilot study shows that the integration of newborn screening into existing primary health-care immu

238 Newborn screening is paramount for early diagnosis and e

239 llowing the sulfatide measurement in DBS for newborn screening of MLD.

240 Newborn screening panels worldwide have been recently ex

241 mains of medicine and public health, such as newborn screening programs, routine laboratory panels, a

242 the estimated efficiency of population-based newborn screening to prevent ketoacidosis, and enables i

243 Newborn screening with direct or conjugated bilirubin me

244 Analogies to imaging, newborn screening, routine testing panels, and antibioti

245 The second Newborn Sequencing in Genomic Medicine and Public Health

246 tal surveys of these domains from the second Newborn Sequencing in Genomic Medicine and Public Health

247 However, newborn serum contains abundant autoantibodies, suggesti

248 elucidating the determinants of the initial, newborn setting of telomere length (TL), it is increasin

249 Female newborns showed higher mitochondrial respiration compare

250 On EEG, L-CS newborns showed lower relative gamma power compared to V

251 When exposed to a newborn skin microenvironment, these cells express hair-

252 t status in rural Bangladesh, but effects on newborn status are unknown.

253 Although gains in newborn survival have been achieved in many low-income a

254 rkedly reduces PTB and dramatically improves newborn survival rates.

255 obstetric conditions of the mothers and the newborn, the obstetric history and socio-demographic bac

256 e new insights into the quantity of Tregs in newborns, their activation state, and their potential to

257 ernal stress significantly predicted shorter newborn TL (beta=-0.079), and positivity significantly p

258 significantly and positively associated with newborn TL (beta=0.114, 95% CI=0.035, 0.189), with each

259 Linear regression was used to predict newborn TL from maternal resilience during pregnancy, ad

260 sychological resilience during pregnancy and newborn TL.

261 increase in resilience predicting 12% longer newborn TL.

262 embrane fluidity in individuals ranging from newborn to nonagenarian.

263 of the visual system in galagos ranging from newborns to adults.

264 Finally, in vitro, newborn Tregs exhibited an increased requirement for TCR

265 was relatively similar, with both adult and newborn Tregs exhibiting a more uniform PD-1(+)CD39(+) p

266 raditional compounds used in the care of the newborn umbilical cord: eucalyptus oil, methylated spiri

267 oteome and metabolome in 88 African-American newborns using faecal samples collected in the first few

268 ndicates that neurogenesis timing may enable newborn V3 INs to interact with different postmitotic di

269 ctional differentiation were not affected by newborn vaccination with the phosphoantigen-containing b

270 ical connectivity, and cortical thickness in newborn voles to appreciate when differences in HC and L

271 Epigenetic age acceleration of 169 newborns was measured from saliva using the Horvath age

272 In newborns, we found no evidence for any intergenerational

273 weeks gestation) and followed them and their newborns weekly for up to 3-6 months post-partum, to doc

274 n the amniotic fluid, shoulder dystocia, and newborn weight (>= 4,000 g) were risk factors for episio

275 Ps and DMR sites and the following outcomes: newborn weight, adiposity, and cord blood glucose, insul

276 Newborns were alive and healthy.

277 Forty-six newborns were macrosomic.

278 1394 newborns were randomly assigned to study groups between

279 In stage 1, all newborns were tested within the first 60 hours of life,

280 es, S100A12 was found to be higher in female newborns when compared with males.

281 d a small effect on mitochondrial density in newborns, which was not significant in this study after

282 Worldwide, many newborns who are preterm, small or large for gestational

283 Of the 91 (0.8%) newborns who failed the HS, 24 (26.4%) were confirmed wi

284 able adult-onset disease risk in 3/85 (3.5%) newborns whose parents consented to receive this informa

285 Another newborn with cCMVI passed the HS but was confirmed with

286 Term newborns with a family history of atopic disease were ra

287 In otherwise healthy newborns with asymptomatic moderate hypoglycemia, a lowe

288 a randomized, placebo-controlled trial, 606 newborns with at least one allergic parent received oral

289 Identification of newborns with cCMV infection allows provision of benefic

290 Archived saliva swabs from newborns with cCMV infection were also tested retrospect

291 All 34 (100%) archived swabs from newborns with cCMV infection were positive by both the C

292 Despite widespread use in the management of newborns with CDH, ECLS has not been consistently associ

293 SL pH might improve innate airway defense in newborns with CF during onset of S. aureus infection.

294 In newborns with CN1, unconjugated bilirubin increased 4.3

295 sonable, cost-effective strategy to identify newborns with early-onset cCMVI-related HL.

296 rmination of neurovascular coupling (NVC) in newborns with encephalopathy.

297 Newborns with positive age acceleration were more likely

298 Routine treatment of moderately preterm newborns with probiotics is unlikely to improve anthropo

299 vels of several inflammatory biomarkers from newborns with ZIKV microcephaly, asymptomatic ZKV infect

300 /L and dosages <600 mg/day had more reactive newborns without an increased risk of cardiac malformati