ライフサイエンスコーパス: nile red

1 marker phosphine 3R and the phospholipid dye nile red.

2 ug-like molecules, 5-fluorouracil (5-FU) and Nile Red.

3 mutants stained with the lipid-sensitive dye Nile Red.

4 rticles encapsulating a model pharmaceutical Nile Red.

5 that modulates the fluorescent properties of Nile Red.

6 The lipid soluble fluorophore Nile Red (9-diethylamino-5-benzo[alpha]phenoxazinone) is

7 ionation in an electrospray plume containing Nile Red, a solvatochromic dye (i.e., a dye for which sp

8 The solvatochromic nature of Nile Red also offers the possibility of plastic categori

9 Nile red and a new silanized form of nile red that can b

10 er of targets, strong intrinsic quenching of Nile red and ANSA dye fluorescence is observed on bindin

11 e cell surface, compared to reference probes Nile Red and DiD, which boosted axial localization preci

12 Micelles loaded with the model drugs Nile red and DiO were used to demonstrate the ROS-depend

13 h the localized encapsulation of hydrophobic Nile red and hydrophilic calcein.

14 ith two different polarity-sensitive probes, Nile red and Prodan.

15 eamlessly combine fluorescence staining with Nile Red and Raman spectroscopy for MP identification an

16 Nile Red and rhodamine 6G molecules prefer the environme

17 entified by staining with the lipophilic dye Nile red and the marker protein ADRP.

18 he bimolecular interaction between the probe Nile Red and the vesicle were evaluated from the uncorre

19 ng the diffusion rates of the dyes ethidium, Nile red, and eosin Y across the outer membrane, as well

20 ixed, stained with the fluorescent lipid dye Nile Red, and imaged by conventional confocal microscopy

21 tionary phase with a polarity-sensitive dye, Nile red, and optical sectioning with confocal microscop

22 of fluorescence using the hydrophobic probe, nile red, and the deposition of mature lamellar unit str

23 ed by encapsulation of the fluorescent probe Nile Red, and the micelle sizes were determined by dynam

24 micelles were preloaded with the model drug Nile red, and the resulting hydrogels demonstrated ROS-d

25 ed that CeO2 NPs and nanocapsules containing Nile red are able to traverse the chorion.

26 nd collisional flux onto the cell surface by Nile red are used to achieve single-molecule localizatio

27 stems for controlled release, the release of Nile Red as a "model payload" was examined.

28 (PE) and polypropylene (PP) materials using Nile red as a fluorescent probe.

29 Here we identify Nile red as a new fluorescent substrate for CaCdr1p, CaC

30 ed for airborne MPs using a combination of a Nile Red-assisted automated fluorescence microscopy tech

31 Here, a Nile Red based spectral point accumulation for imaging i

32 a sensitive fluorescent molecular probe, the Nile Red-based solvatochromic antimicrobial peptide UNR-

33 by a super-resolution microscopy technique: Nile Red-based spectrally resolved point accumulation fo

34 d an array of solvatochromic probes based on Nile Red bearing ligands for specific targeting of the e

35 osed that the reformation of the fluorescent Nile Red becomes chemically "gated" in the organic phase

36 The Nile Red binding site is competitively eliminated by itr

37 gomers were more hydrophobic (as measured by Nile Red binding) and were highly toxic to neuronal cell

38 Together, the data suggest that Nile Red binds to the active site with high affinity ( a

39 Nile Red binds with apparent Kd values of 0.05 and 2.3 m

40 mpound 1 had three hydroxyl groups more than Nile Red, but was surprisingly insoluble in aqueous medi

41 This indicates that Nile red can be used for the identification of inhibitor

42 tent among different species, in contrast to Nile red cell staining procedures.

43 atography and mass spectrometry (GC-MS), and Nile red cell staining suffer drawbacks, including poor

44 mission compared to direct excitation of the nile red chromophore at 540 nm.

45 containing a two-photon absorbing dye and a nile red chromophore has been synthesized.

46 Nile Red (compound A) fluoresces at about 530 nm with go

47 vesicle radius distributions, and the linear Nile Red concentration dependence of the mean off-time.

48 a sigmoidal dependence of heme spin state on Nile Red concentration, where the first equivalent of Ni

49 s well as excited-state lifetimes at varying Nile Red concentrations, indicate a high-affinity site t

50 Oxidation-responsive release of encapsulated Nile Red demonstrates the potential of these micelles as

51 is approaches to a series of monosubstituted Nile Red derivatives (9-diethylbenzo[a]phenoxazin-5-ones

52 release the corresponding highly fluorescent Nile red derivatives in the final step.

53 The hypothesis tested in this paper is that Nile Red derivatives that incorporate water-solubilizing

54 Thus three Nile Red derivatives, 1-3, were prepared.

55 The solvatochromic dye Nile Red dispersed in selected hydrogen bond acidic poly

56 er applicability is tested by imaging ~80 nm Nile red-doped polystyrene and ~90 nm silver nanoparticl

57 rinsic fluorescence, and fluorescence of the Nile red dye bound to OCP.

58 d by imaging the fluorescence intensity from Nile red dye doped into suspended 1,2-diphytanoyl-sn-gly

59 Fluorescent staining with Nile red dye has proven to be effective at distinguishin

60 put microplate assay was developed that uses Nile red dye to quantify neutral lipids that have been e

61 e fluorescent probes based on solvatochromic nile red dye, conjugated to a HaloTag reactive targeting

62 ontaining inorganic oxides as a quencher for Nile Red dye.

63 ned with the environment-sensitive ACDAN and Nile Red dyes.

64 Nile Red efflux assays and RT-qPCR analysis suggest ospe

65 lipophilic dye-maleimide and the blocking of Nile red efflux by covalent labelling with bulky maleimi

66 larly, the presence of Ag(I) slowed down the Nile red efflux in the parent strain more significantly

67 fficiency, along with a 3.4-fold increase in nile red emission compared to direct excitation of the n

68 Surprisingly, both "free" and silicate-bound nile red exhibit relatively facile translational motions

69 orescent labelling of Nylon microfibers with Nile Red facilitated imaging.

70 es of unsaturated triglyceride oils, whereas Nile Red failed to properly estimate the local polarity

71 An increase in Nile Red fluorescence (a proxy for cellular neutral lipi

72 ion in a membrane pattern was observed using Nile red fluorescence histochemistry.

73 al extracts contained pigments that quenched Nile red fluorescence, a mild bleach solution was used t

74 lastic particles (20-1000 mum) using the dye Nile red, fluorescence microscopy, and image analysis so

75 at sustained local release of the model drug Nile red for 14 days in vivo.

76 Enniatin selectively inhibited the efflux of Nile red from S. cerevisiae cells expressing CaCdr1p or

77 uor white and Evans blue dyes in addition to Nile red, ground arthropod biomass appeared blueish-purp

78 o enable phototriggerable release of trapped Nile Red guest molecules from the cubosome structure in

79 ar to be longer in duration, suggesting that Nile red has a higher affinity to the bubble surface.

80 Further, Nile Red has a very poor solubility in aqueous media.

81 on excited fluorescence microscopy, to which Nile Red has never been optimized.

82 asure residence times of the fluorescent dye Nile Red in CYP3A4 incorporated in surface-immobilized l

83 The means of the on-time distributions of Nile Red in DMPC and SOPC vesicles were significantly di

84 anic dyes, 1,6-diphenyl-1,3,5-hexatriene and Nile red, in close proximity.

85 concentration, where the first equivalent of Nile Red increased the high-spin fraction by only 13% of

86 rescence emission data of the nonpolar probe Nile red indicate that hydrophobic domains become availa

87 tructure, and the fluorescence properties of Nile red indicate the exposure of hydrophobic surface ar

88 Nile Red is a benzo[a]phenoxazone dye containing a dieth

89 expectedly rapid diffusion of silicate-bound nile red is attributed to the presence of liquidlike sil

90 Mass spectrometry analysis indicates that Nile Red is metabolized sequentially by CYP3A4 to the N-

91 In addition, Nile Red is sequentially oxidized at rates comparable to

92 Nile Red is shown to be a useful probe of the structural

93 ronment-sensitive fluorophores acrylodan and Nile Red, it was observed that the activation of peptide

94 abeling events using rhodamine fluorophores, Nile red-labeled events appear to be longer in duration,

95 Flow cytometry analysis of Nile red labeling revealed a reduction in cholesterol es

96 fer from the two-photon absorbing dye to the nile red moiety, with an 8-fold increase in emission com

97 adsorption and desorption process of single Nile red molecules at the nanobubble surface.

98 n coefficients for "free" and silicate-bound nile red molecules in the 1:9 films are 3.9 x 10(-10) an

99 nteresting observations, we hypothesize that Nile red molecules may start clustering and form some ki

100 Nile Red molecules were observed to associate with and d

101 ciation and dissociation reactions of single Nile Red molecules with a vesicle have been studied.

102 The interactions of single Nile Red molecules with DMPC and SOPC lipid bilayers wer

103 ain nanobubbles being co-labeled by multiple Nile red molecules, resulting in the observation of supe

104 By loading Nile red (NiR) as an acceptor, an artificial light-harve

105 In the presence of a second dye, Nile Red (NiR), an unusual sequential two-step energy tr

106 ssfully utilized to trap the hydrophobic dye Nile Red (NR) and the anticancer drug doxorubicin (DOX).

107 on of iron (III) (ferric iron, Fe(3+)) using Nile red (NR) as a complexing agent.

108 Nile red (NR) dye was used as a fluorescent tracer.

109 we report that the sequential metabolism of Nile Red (NR) is accelerated by the heterotropic alloste

110 favorable kinetics for the release of either Nile Red (NR) or lysozyme (LYS), loaded with gel precurs

111 The emission of Nile Red (NR), a polarity sensing dye, was used to probe

112 environmental sensitive fluorophores namely Nile Red (NR), Eosin Y (EY) and Rose Bengal (RB).

113 ased on selective fluorescent staining using Nile Red (NR), followed by density-based extraction and

114 )](3), CrBPh(4)) and an inert reference dye (Nile Red, NR or 5,10,15,20-tetrakis(pentafluorophenyl) p

115 activity was measured as the accumulation of Nile Red O-positive lipid vacuoles, and osteogenic activ

116 rties, and study of the sensing mechanism of Nile red Pd-based CO chemosensors, structurally modified

117 Nile Red/poly(methyl methacrylate) films prepared for co

118 ry low detection limits compared to previous Nile Red/polymer matrix fluorescence vapor sensors.

119 In these plugs, along with Nile Red-positive adipocytes, we found MC/Mph distribute

120 The mechanism of Nile Red release was investigated by monitoring the chan

121 tly bound to lipid membranes, revealing that Nile red's (NR) orientation spectra are extremely sensit

122 ace hydrophobicity of the plastic decreases, Nile red's fluorescence signal undergoes a corresponding

123 Changes in Nile red's fluorescence spectra were observed upon expos

124 re found to have a substantial effect on the Nile red sensor fluorescence quantum yields, hereby defi

125 ity to LDs, whereas the parent aldehydes and Nile Red showed a detectable backgrounds from intracellu

126 spectral phasor can be used to decompose the Nile Red signal into 2 components and perform 3-color im

127 ments performed on "free" and silicate-bound nile red species extracted into chloroform solutions pro

128 Nile Red spectroscopy identified histologically intact y

129 Nile Red spectroscopy offers a relatively simple yet hig

130 hown to be necessary for the accumulation of Nile Red-stained fat in C. elegans.

131 sults provide an explanation for the loss of Nile Red-stained fat in pgp-2(-) animals as well as insi

132 collected microplastic samples enumerated by Nile Red staining and flow cytometry.

133 Live imaging studies by Nile red staining suggested that both polar and nonpolar

134 MR) spectroscopy and fluorescence detection (Nile Red staining) to interrogate Mycobacterium tubercul

135 so induced TAG accumulation, as suggested by Nile Red staining.

136 orescently image individual nanobubbles with Nile red suggests that the gas/solution interface is hyd

137 Nile red and a new silanized form of nile red that can be covalently attached to the silicate

138 ionalization strategy for solvatochromic dye Nile Red that improves its photostability is presented.

139 onstrated for molecules such as estrogen and Nile Red, the absorption of small hydrophobic molecules

140 dyes, such as parent aldehydes and reference Nile Red, the new dyes exhibited strong fluorescence que

141 ttempted to measure fluorescence of released Nile red to determine whether the structural adjustments

142 solvatochromic and fluorogenic properties of nile red to extract both the emission spectrum and the p

143 larity-sensitive, solvatochromic fluorophore Nile red to label and probe individual hydrogen nanobubb

144 By using dual fluorochrome dyes (Hoechst and Nile Red) to locate nucleus and cellular cytoplasm, resp

145 one- and two-photon excited fluorescence of Nile Red turns out to be very responsive to substitution

146 Dye leakage assays using the hydrophobic dye Nile red validated that ATP-driven release was selective

147 Nile red was effluxed efficiently from Saccharomyces cer

148 ccumulate in the brain, whereas encapsulated Nile red was rapidly cleared.

149 .4, the fluorescence of micelle-encapsulated Nile Red was relatively constant, indicating it was reta

150 ntification in the stereomicroscope or using Nile Red were excluded due to the small size of particle

151 lization, additional candidate quenchers for Nile Red were identified based on Lewis acid/base intera

152 The near-IR fluorescent probe Nile Red, which has strong solvatochromic behavior, was

153 verages the change in fluorescence of a dye, Nile Red, which is adsorbed on an oxygen plasma-treated

154 ining procedure involving the lipophilic dye Nile Red, whose fluorescence spectrum varies according t

155 hic beads indicates that the interactions of Nile red with C18 bonded phase are different between bea

156 4-(dimethylamino)naphthalamide and thionated Nile Red with near-infrared radiation leads to the effic

157 ition for hydrogen-bonding interactions with Nile Red yielded flourescent films with high sensitivity