ライフサイエンスコーパス: nitroaniline

1 A), which releases the chromogenic product p-nitroaniline.

2 oagulans to release a chromogenic product, p-nitroaniline.

3 l amide bond present in N-gamma-L-glutamyl-4-nitroaniline.

4 brium formation constant of each acid with 4-nitroaniline.

5 sing base hydrolysis to afford substituted 2-nitroanilines.

6 cumented, but little is known about those of nitroanilines.

7 repared from the appropriate 2-substituted 4-nitroanilines.

8 compounds, 2-nitroaniline, 3-nitroaniline, 4-nitroaniline, 1-chloro-2-nitrobenzene, 1-chloro-3-nitrob

9 .50%; the highest yields were observed for 4-nitroaniline, 3-chloroaniline, and 4-(methylsulfonyl)ani

10 show that all the nitroaromatic compounds, 2-nitroaniline, 3-nitroaniline, 4-nitroaniline, 1-chloro-2

11 e nitroaromatic compounds, 2-nitroaniline, 3-nitroaniline, 4-nitroaniline, 1-chloro-2-nitrobenzene, 1

12 idazole (8) was prepared from 4,5-difluoro-2-nitroaniline (5) via successive reduction, cyclization,

13 and N-carbobenzoxyglycylprolyl-L-arginine-p-nitroaniline (a substrate for both enzymes), the specifi

14 of H-D-phenyalanyl-L- pipecolyl-L-arginine-p-nitroaniline (a thrombin substrate) than that of trypsin

15 l-L-isoleucyl-L-glutamylglycyl-L-arginine- p-nitroaniline (a trypsin substrate) and N-carbobenzoxygly

16 detected, as one sample contained 2-methyl-5-nitroaniline, a potententially carcinogenic compound.

17 rticular, the sensor shows specificity for 4-nitroaniline and 1-chloro-2-nitrobenzene over other nitr

18 dure from commercially available 4-methoxy-2-nitroaniline and 1-iodo-4-methoxy-2-nitrobenzene.

19 degraded via two intermediates: 2-methoxy-5-nitroaniline and 4-methoxy-3-nitroaniline, to the amine

20 r relationships between the E(T) values of 4-nitroaniline and N,N-dimethyl-4-nitroaniline and the ket

21 nships are seen between the E(T) values of 4-nitroaniline and N,N-dimethyl-4-nitroaniline and the log

22 For 4-nitroaniline and N,N-dimethyl-4-nitroaniline bathochromi

23 lar transition energies indicates that for 4-nitroaniline and N,N-dimethyl-4-nitroaniline the stabili

24 y using different nitroaromatic compounds [m-nitroaniline and p-nitroaniline] and nitrobenzenes [nitr

25 values of 4-nitroaniline and N,N-dimethyl-4-nitroaniline and the keto-enol ratio of acetylacetone in

26 values of 4-nitroaniline and N,N-dimethyl-4-nitroaniline and the log of the second-order rate consta

27 are performed with nitroaromatic compound 4-nitroaniline and the results are statistically studied b

28 esis of a series of quinoxalines from both 2-nitroanilines and 1,2-diamines is demonstrated.

29 nonsymmetrically substituted 4,5-dialkoxy-2-nitroanilines and 1-bromo-2-nitrobenzenes via Buchwald-H

30 imidazoles by redox-economical coupling of o-nitroanilines and alcohols.

31 itroaromatic compounds [m-nitroaniline and p-nitroaniline] and nitrobenzenes [nitrobenzene, p-nitroto

32 yper-Rayleigh scattering (HRS) relative to p-nitroaniline are reported.

33 lytic activity by using N-gamma-L-glutamyl-4-nitroaniline as a substrate, although the GGT was shown

34 ine-p-nitroanilide producing L-alanine and p-nitroaniline as products; the formation of the latter pr

35 The chosen matrix was p-nitroaniline, as it generated superior sensitivity when

36 n have been synthesized with an N-acylated p-nitroaniline at position P1' and examined as substrates

37 pectral shifts these media impart on various nitroanilines at 25 degrees C.

38 For 4-nitroaniline and N,N-dimethyl-4-nitroaniline bathochromic shifts of 51.3 and 62.0 nm, re

39 A meso-p-nitroaniline-calix[4]pyrrole derivative trans-coordinate

40 d benzopodophenazine (10), and their 4beta-p-nitroaniline derivatives 13-15.

41 Para-nitroaniline derivatives with peripheral 1,2- and 1,3-di

42 Noticeably, starting from o-nitroaniline derivatives, in the presence of alcohols, b

43 crystal, 2,6-dichlorobenzylidine-4-fluoro-3-nitroaniline (DFNA), which also shows thermosalient beha

44 yzing the degradation of Na-gamma-glutamyl-4-nitroaniline (GNA) and the hydrolysis of glutathione, re

45 we synthesized novel substrates linking a p-nitroaniline group to adenylate (AMP-pNA) and inhibitors

46 he solvated boronic acid ester unit on the 4-nitroaniline group, predominantly through inductive inte

47 bstrate (N-benzoyl-L-Ile-L-Glu-L-Gly-L-Arg-p-nitroaniline hydrochloride) (S-2222).

48 triazine (1d) obtained in three steps from 2-nitroaniline in 37-55% yields.

49 nts for aminolyses of acetyl chloride with m-nitroaniline in methanol at 0 degrees C show that acetyl

50 iding synthetically useful N-nitroso N-alkyl nitroanilines in excellent yields which can be easily co

51 sitive to the polarity of the medium and the nitroanilines investigated all exhibited varying degrees

52 iline and 1-chloro-2-nitrobenzene over other nitroaniline isomers and nitrochlorobenzene isomers, res

53 substrate that is a methionyl analogue of p-nitroaniline (L-Met-p-NA), which releases the chromogeni

54 hotocleavable amides of 5-methoxy-N-methyl-2-nitroaniline (MMNA) were introduced.

55 have all been replaced with a chromophoric p-nitroaniline moiety which is directly linked to the bond

56 ated were 2,5-dihydroxybenzoic acid (DHB), 4-nitroaniline (NA), alpha-cyano-4-hydroxycinnamic acid (C

57 puter fitting of the cyclic voltammetry of 4-nitroaniline, NA, plus 1,3-diphenylurea in DMF shows ess

58 ntriol (DIT), 1,5-diaminonapthalene (DAN), p-nitroaniline (NIT), 9-aminoacridine (9-AA), and 2-mercap

59 proposed for solvolyses and aminolyses by m-nitroaniline of acetyl chloride (i.e. these reactions ar

60 reduced through the intermediate 2-methoxy-5-nitroaniline or 4-methoxy-3-nitroaniline to 2,4-diaminoa

61 gher affinity for tPA than substrates with p-nitroaniline or 7-amino-4-methylcoumarin leaving groups.

62 ning in easily accessible N-(2-furylethyl)-2-nitroanilines or their heterocyclic analogues followed b

63 gues of 7-amido-4-methylcoumarin (AMC) and p-nitroaniline (pNA), utilizing new fluorescence-based and

64 amino-4-methylcoumarin, AMC), and m/z 139 (p-nitroaniline, pNA).

65 ubstrate L-pyroglutamyl-L-prolyl-L-arginyl-p-nitroaniline (S-2366) and on the activation of factor IX

66 For 2,6-dibromo- and 2,6-diiodo-4-nitroaniline smaller red shifts of 19.0 and 9.0 nm, resp

67 s that for 4-nitroaniline and N,N-dimethyl-4-nitroaniline the stabilization of the zwitterionic excit

68 iate 2-methoxy-5-nitroaniline or 4-methoxy-3-nitroaniline to 2,4-diaminoanisole.

69 es: 2-methoxy-5-nitroaniline and 4-methoxy-3-nitroaniline, to the amine product 2,4-diaminoanisole.

70 nes reduced selectively to the corresponding nitroanilines under the present reaction conditions.

71 ficant positive solvatochromic effect on the nitroaniline unit (R(1) = -CH(3)) as result of the solve

72 e number and position of substituents on the nitroaniline unit were found to play a key role in the r

73 The amine of the reporter group (a nitroaniline unit) was a constituent part of a carbamate

74 d into N-alkyl phenylenediamines and N-alkyl nitroanilines using Zn-AcOH and HCl/MeOH, respectively.

75 s of succinyl-Ala-Ala-Pro-Phe-anilides for p-nitroaniline versus aniline leaving groups with variants

76 e newly formed scissile bond releases free p-nitroaniline which is yellow-colored and can be continuo

77 dipeptide by the aminopeptidase releases a p-nitroaniline, which is monitored spectrophotometrically

78 as prepared by first coupling 2,5-dichloro-4-nitroaniline with 2-mercapto-N,N-dimethylbenzamide.

79 nonsymmetrically substituted 4,5-dialkoxy-2-nitroaniline with a 1-bromo-2-nitrobenzene derivative fe

80 The new method involves condensation of o-nitroaniline with glyoxylate in methanol followed by tre

81 d the lipid response enhancing UV-absorber p-nitroaniline with the protonating agent butyric acid.

82 zed in two steps by treating the substituted nitroanilines with 2,5-dimethoxy-tetrahydrofuran to affo