ライフサイエンスコーパス: nitrosative

1 ung injury), immuno-histochemical (oxidative/nitrosative and blood-brain barrier markers) as well as

2 s reduced diabetes-induced retinal oxidative-nitrosative and endoplasmic reticulum stress and glial a

3 vents cell death via inhibiting Fe-dependent nitrosative and oxidative cytotoxicity.

4 OPD, with these differences regulated by the nitrosative and oxidative free radicals and cytokines th

5 or yjbI resulted in altered sensitivities to nitrosative and oxidative stress and iron deprivation.

6 nd reactive oxygen species (ROS), generating nitrosative and oxidative stress conditions in the embry

7 onic infection phase, and that resistance to nitrosative and oxidative stress may be the mechanism of

8 Different markers of mitochondrial activity, nitrosative and oxidative stress, apoptosis, and inflamm

9 developed mechanisms to resist host-imposed nitrosative and oxidative stresses.

10 ostnatal growth results in increased cardiac nitrosative and oxidative-stress and DNA damage, which c

11 Consistent with the underlying nitrosative and thiol-oxidative chemistry, growth inhibi

12 iptional network that responds to oxidative, nitrosative, and heat stresses in Mycobacterium tubercul

13 Here we show that NO accretion during the nitrosative burst promotes increasing S-nitrosylation of

14 orous proliferation, a substantial oxidative/nitrosative burst, and a proinflammatory cytokine respon

15 06), moderate proliferation, a low oxidative/nitrosative burst, and a regulatory/anti-inflammatory cy

16 h by depleting T(regs) through oxidative and nitrosative bursts, and suggest that As(2)O(3) could be

17 unrelated mechanisms, including hydrolysis, nitrosative chemistry, and deaminase enzymes.

18 nein suppresses Ang II-induced NOX-dependent nitrosative damage and cell death in both nondiabetic an

19 otection of the wound site against oxidative/nitrosative damage and prevention of hyaluronic acid deg

20 yclooxygenase type 2, and cellular oxidative/nitrosative damage are reduced when the TLR-4 pathway is

21 MCI could be important to determine whether nitrosative damage directly contributes to AD.

22 day for 2 weeks) also induced apoptosis and nitrosative damage in both diabetic and nondiabetic WT h

23 umber of studies reported that oxidative and nitrosative damage may be important in the pathogenesis

24 These findings suggest that nitrosative damage occurs early in the course of MCI, an

25 We concluded that the oxidative/nitrosative damage resulting from the testosterone-plus-

26 Collectively, these data suggested that nitrosative damage to proteins harbouring free or zinc-b

27 B. burgdorferi cells with DEA/NO resulted in nitrosative damage to several proteins, including the zi

28 tion, steatosis, and increased oxidative and nitrosative damage to the mitochondrion.

29 cardiomyocytes increased cardiac apoptosis, nitrosative damage, and membrane translocation of the ni

30 es_1165, that is implicated in the repair of nitrosative damage.

31 extracytoplasmic proteins are repaired after nitrosative damage.

32 2'-deoxyxanthosine and 2'-deoxyinosine from nitrosative deamination; 8-oxo-2'-deoxyguanosine from ox

33 celerate loss of heterozygocity by enhancing nitrosative DNA damage.

34 als, including those initiated by oxidative, nitrosative, genotoxic, oncogenic, thermal, inflammatory

35 that CHT inhibition is not due to oxidative-nitrosative inactivation of the protein and that decreas

36 ations in the hormonal milieu with oxidative/nitrosative/inflammatory damage to the prostate epitheli

37 t mechanisms governing Cdc25A in response to nitrosative insult.

38 f IL1R, IL17RA, S1P1, and S1P3 together with nitrosative markers in astrocytes within MS and EAE lesi

39 egulation of Bcl-2 phosphorylation is due to nitrosative modification of B56delta, which we identify

40 thiol(s) from further irreversible oxidative/nitrosative modification.

41 catalytic cysteine residues to oxidative and nitrosative modifications.

42 In Escherichia coli, nitrosative mutagenesis may occur during nitrate or nitr

43 The results suggest that nitrosative mutagenesis occurs during a shift from nitra

44 wo agents is more responsible for endogenous nitrosative mutagenesis.

45 The response to this nitrosative (NO-triggered) stress is controlled by the C

46 particularly vulnerable to heat, acidic pH, nitrosative or oxidative stress, yet exhibited high mito

47 ower cGMP concentration (P<0.001) and higher nitrosative/oxidative stress (P<0.05).

48 We identified increased nitrosative/oxidative stress and impaired microvascular

49 Thus, our data provide a direct link between nitrosative/oxidative stress and neurodegenerative disor

50 rt a pathway whereby basal and toxin-induced nitrosative/oxidative stress results in S-nitrosylation

51 ol by cyclic guanosine monophosphate (cGMP), nitrosative/oxidative stress, and brain natriuretic pept

52 , and nitrotyrosine expression, a measure of nitrosative/oxidative stress.

53 ive) and was related to increased myocardial nitrosative/oxidative stress.

54 generative disorders such as PD that involve nitrosative/oxidative stress.

55 paramagnetic resonance spectroscopy, HPLC), nitrosative (ozone-based chemiluminescence) and inflamma

56 e possible metal-dependent, O(2)-independent nitrosative pathway is the reaction of thiols with dinit

57 Several candidate nitrosative pathways involve the reaction of *NO with O(

58 The results suggest that the nitrosative pressure (NO burst) is higher in NE plants,

59 er to attenuation of the effects of NO or to nitrosative protein damage.

60 hich influences iron-dependent oxidative and nitrosative radical species generation.

61 de the cell, as opposed to cellular entry of nitrosative reactants from the extracellular compartment

62 n, indicating that the dominant oxidative or nitrosative reactions are not influenced by acidic pH.

63 and recapture NO(.) reversibly, and exhibit nitrosative reactivities toward a wide range of biologic

64 1 governs pathogenesis via the regulation of nitrosative resistance and nitrogen metabolism in V. dah

65 involved in NO-generation suggested that the nitrosative status of leaves and roots was altered by Na

66 idative stress (8-hydroxy guanosine levels), nitrosative stress (nitrotyrosine formation), and apopto

67 amined if exaggerated oxidative-inflammatory-nitrosative stress (OXINOS) and corresponding decrease i

68 exaggerated systemic oxidative-inflammatory-nitrosative stress (OXINOS), defined by an increase in f

69 bin III resulted in a reduction of pulmonary nitrosative stress (p = 0.002), airway obstruction (bron

70 Yet, how this nitrosative stress affects iNOS function in vivo is poor

71 crease in oxidative stress and minimal to no nitrosative stress after long-term alcohol feeding of an

72 GPI-15427 (20 microM) prevented oxidative-nitrosative stress and cell death in palmitate-exposed p

73 vel can trigger detrimental oxidative and/or nitrosative stress and damage events.

74 treatment of cancer cells with SNCEE induced nitrosative stress and decreased Cdc25A protein levels i

75 nce of the glucose stimulus, consistent with nitrosative stress and dysfunctional exocytosis, precedi

76 Oxidative/nitrosative stress and endothelial dysfunction are hypot

77 This link between placental nitrosative stress and exposure to fine particle air pol

78 on, diet-induced obesity increases lysosomal nitrosative stress and impairs autophagy in the liver, l

79 Low-dose arginine vasopressin reduced nitrosative stress and improved cardiopulmonary function

80 ADMA treatment induced the brain nitrosative stress and inflammation as well as enhanced

81 tochondrial biogenesis as well as decreasing nitrosative stress and inflammation, thereby attenuating

82 These findings suggest that oxidative/nitrosative stress and inflammatory stimuli may trigger

83 riptional repressor NsrR in response to both nitrosative stress and intracellular free iron concentra

84 aureus to maintain redox homeostasis during nitrosative stress and is essential for virulence.

85 f ischemia-reperfusion-induced oxidative and nitrosative stress and is therefore of potential therape

86 01 activation, contribute to increased oxido-nitrosative stress and lung protein nitration.

87 te numerous reports on the role of oxidative/nitrosative stress and mitochondrial dysfunction in hepa

88 tions of VdAtf1 in pathogenesis, response to nitrosative stress and nitrogen metabolism in V. dahliae

89 ngs support an association between oxidative/nitrosative stress and SLE.

90 st that HboN may function in protection from nitrosative stress and that HboO may act as an oxygen tr

91 aA and crp deletion mutants are sensitive to nitrosative stress and the superoxide generator methyl v

92 aimed at eNMDARs may decrease Abeta-induced nitrosative stress and thus ameliorate neurotoxic damage

93 eed of cells to rapidly respond to oxidative/nitrosative stress and to temporally regulate thiol-base

94 tinal injury by suppressing inflammation and nitrosative stress and underlying sepsis-induced lethali

95 Oxidative and nitrosative stress are key to the pathogenesis of alcoho

96 the mechanisms by which NO and GSNO mediate nitrosative stress are not well understood.

97 ed plasticity-related pathways and oxidative/nitrosative stress are part of the dendritic spine patho

98 mechanisms through which NO and GSNO mediate nitrosative stress as well as the cellular pathways of p

99 egulators that mediate adaptive responses to nitrosative stress but does not affect methionine requir

100 xidation end-products in spite of comparable nitrosative stress but likely reduced NOS3.

101 e ethanol-induced liver injury by decreasing nitrosative stress but not in a more chronic scenario wh

102 entral role in the response of Salmonella to nitrosative stress but requires precise regulation to av

103 reus is capable of metabolically adapting to nitrosative stress by expressing an NO.-inducible L-lact

104 ) protein residues, indicating that reducing nitrosative stress by way of the L-citrulline/NO. pathwa

105 C development in the context of uncontrolled nitrosative stress can be blocked by pharmacologic inhib

106 These findings provide an example of how nitrosative stress can exert action at the atomic level.

107 bacteria, it can also protect itself against nitrosative stress caused by NO generated when nitrite a

108 A cmr mutant was better able to survive a nitrosative stress challenge but was attenuated in a mou

109 Nitrosative stress decreased the Cdc25A-bound fraction o

110 while in the oral cavity, the mechanisms of nitrosative stress defense are not well understood in th

111 applied to measuring bacterial oxidative and nitrosative stress dynamics under different conditions i

112 ine abrogated the toxicity and the oxidative/nitrosative stress elicited by the induction of CYP2E1.

113 s a limited set of genes to combat oxidative/nitrosative stress encountered in its tick vector or mam

114 In contrast, LMW thiols diminish the nitrosative stress experienced by enzymes, such as gluta

115 l conditions such as hypoxic, oxidative, and nitrosative stress found at sites of infection.

116 Oxidative and nitrosative stress have been implicated in prostate carc

117 s shown to play a role in protection against nitrosative stress in addition to the previously identif

118 ces NO formation and increases oxidative and nitrosative stress in airway epithelial cells.

119 xygen or nitric oxide to combat oxidative or nitrosative stress in bacteria, archaea, and some protoz

120 upport accumulating evidence that implicates nitrosative stress in cardiac and muscle disease.

121 d by DNA damage caused by vascular oxidative-nitrosative stress in cerebral endothelial cells, which,

122 nd COX may mediate hormone-induced oxidative/nitrosative stress in epithelium.

123 Analysis of nitrosative stress in MCI could be important to determin

124 nitric oxide (NO) production, which promotes nitrosative stress in metabolic tissues such as liver an

125 receptors, interleukin (IL) 1R, IL17RA, and nitrosative stress in multiple sclerosis (MS) plaques, e

126 dendrites and Zn(II) release resulting from nitrosative stress in neurons.

127 e molecular mechanisms of protection against nitrosative stress in P. gingivalis and shows that the r

128 ate the status and contribution of oxidative/nitrosative stress in patients with SLE.

129 To understand the role of nitrosative stress in prostate cancer progression, we in

130 production of peroxynitrite which may cause nitrosative stress in pulmonary vasculature.

131 tal ventral hippocampus lesion had oxidative/nitrosative stress in the brain as well as in the periph

132 erns of PhoP-activated genes during moderate nitrosative stress in the innate host response.

133 nefit in ovine acute lung injury by reducing nitrosative stress in the lung and limiting the degree o

134 Increased oxidative-nitrosative stress in the microenvironment of cholinergi

135 have measured different molecular markers of nitrosative stress in three stably transfected cell line

136 he role of H2 in prevention of oxidative and nitrosative stress in UVB irradiated corneas, which may

137 ionylation reactions following oxidative and nitrosative stress in vitro and in vivo.

138 nced later in life through particle-mediated nitrosative stress incurred during fetal life.

139 Nitrosative stress induced a switch from a contractile t

140 utrophils displayed increased sensitivity to nitrosative stress induced apoptosis ex vivo and increas

141 We found that nitrosative stress induced by steady-state nitric oxide

142 lar granule neurons (CGNs) that oxidative or nitrosative stress induces an N-terminal cleavage of opt

143 eport that exposure of target HL-60 cells to nitrosative stress inhibited APLT, induced PS externaliz

144 host apart from protecting the bacilli from nitrosative stress inside the activated macrophages, con

145 ning aerobic respiration under conditions of nitrosative stress is a key factor for host colonisation

146 Increased oxidative/nitrosative stress is a major contributing factor to alc

147 These results suggest that increased nitrosative stress is critically important in promoting

148 Nitrosative stress is induced by pathophysiological leve

149 Additionally, our findings suggest that nitrosative stress is mediated principally via the S-nit

150 the relationship between S-nitrosylation and nitrosative stress is more complex.

151 ely modified under alcohol-induced oxidative/nitrosative stress is poorly understood.

152 One major marker of nitrosative stress is the formation of 3-Nitrotyrosine (

153 hanism behind polyamine-mediated rescue from nitrosative stress is unclear, but it is not attributabl

154 ed the hypothesis that cardiac oxidative and nitrosative stress leading to DNA damage and accelerated

155 Our findings show that nitrosative stress leads to dysfunctional ER stress sign

156 r histopathology, serum transaminase levels, nitrosative stress markers, and activities of oxidativel

157 were evaluated for serum levels of oxidative/nitrosative stress markers, including antibodies to malo

158 Oxidative/nitrosative stress may be important in the pathology of

159 AI scores suggests that markers of oxidative/nitrosative stress may be useful in evaluating the progr

160 ion, a situation possibly exacerbated by the nitrosative stress of concurrent inflammation.

161 ne restored plasticity and reduced oxidative/nitrosative stress of prefrontal cortex pyramidal cells,

162 rial dysfunction resulting from oxidative or nitrosative stress often acts as an initiating stimulus

163 for either nitric oxide-dependent oxidative/nitrosative stress or for the increased presence of the

164 eased IR-induced inflammatory, oxidative and nitrosative stress promote intestinal injury and sepsis-

165 Although other putative nitrosative stress protection mechanisms present on the

166 first part of this review, the oxidative and nitrosative stress relation with cancer are described.

167 vement in iron mineralization, oxidative and nitrosative stress resistance and anaerobic ammonium oxi

168 globin is a key enzyme involved in microbial nitrosative stress resistance and nitric oxide degradati

169 to hmp are important for NO. detoxification, nitrosative stress resistance and Salmonella virulence.

170 that regulates expression of respiration and nitrosative stress resistance genes.

171 Staphylococcus aureus nitrosative stress resistance is due in part to flavohem

172 required for nitric oxide detoxification and nitrosative stress resistance under aerobic conditions.

173 to be directly involved in the oxidative and nitrosative stress response in E. coli.

174 (FDPs) play important roles in the microbial nitrosative stress response in low-oxygen environments b

175 sis revealed that rather than regulating the nitrosative stress response like Streptomyces coelicolor

176 ggesting that it plays a primary role in the nitrosative stress response.

177 he hybrid cluster protein and contributes to nitrosative stress responses.

178 to phosphorylate ULK1 at S317 in response to nitrosative stress resulted in increased autophagy: the

179 protein S-nitrosylation directly implicates nitrosative stress resulting from AniA-dependent nitric

180 Oxidative and nitrosative stress resulting in mitochondrial dysfunctio

181 , with their dysfunction under conditions of nitrosative stress serving as a mechanistic basis for in

182 ichia coli display far greater resistance to nitrosative stress than the K-12 reference strain MG1655

183 Here we describe an adaptive response to nitrosative stress that allows S. aureus to replicate at

184 However, the potential for oxidative/nitrosative stress to elicit an autoimmune response or t

185 is particularly important for resistance to nitrosative stress under anaerobic conditions.

186 The present study aimed to target nitrosative stress using a naturally occurring Nos2 inhi

187 dings suggest that ENV-mediated induction of nitrosative stress via activation of TLR4 results in an

188 Interestingly, oxidative/nitrosative stress was also detected in the periphery of

189 duction are coordinated with the response to nitrosative stress were revealed.

190 nas gingivalis must withstand high levels of nitrosative stress while in the oral cavity, the mechani

191 Salmonella experiences oxidative and nitrosative stress within host phagocytes, and CyaY-depe

192 hich serve to protect the microorganism from nitrosative stress within the intracellular environment.

193 hat the HIV-1 Tg rat brain shows evidence of nitrosative stress without appropriate oxidation-reducti

194 levated temperature, and increased oxidative/nitrosative stress) and evade the immune response.

195 These included nitrosative stress, accumulation of endoplasmic reticulu

196 of morphological abnormalities and oxidative/nitrosative stress, among others.

197 xpression of genes associated with oxidative/nitrosative stress, anaerobic respiration and lactate me

198 luconate dehydratase-dependent growth during nitrosative stress, and a cyaY mutation reduces Salmonel

199 Since ammonia is known to induce oxidative/nitrosative stress, and antioxidants and nitric-oxide sy

200 e-induced endothelial cell oxidative stress, nitrosative stress, and apoptosis was determined by usin

201 in virulence, including cell wall stability, nitrosative stress, and extracellular capsule production

202 Hepatocellular damage, oxidative and nitrosative stress, and inflammation were also quantifie

203 s, causes impaired cell signaling, oxidative-nitrosative stress, and inflammation.

204 y decreased myocardial NOX-2 levels, reduced nitrosative stress, and lower matrix metalloproteinase-2

205 ical role for thioredoxin in protection from nitrosative stress, and suggest new approaches to manipu

206 enes required for defense against NO-induced nitrosative stress, and that diversification of signal p

207 Typhimurium growth during nitrosative stress, and the hcp-hcr locus plays a suppor

208 Nitrosative stress, as generated by ASN, can stimulate c

209 These changes occurred along with reduced nitrosative stress, as indicated by lower plasma levels

210 Emerging evidence suggests that oxidative/nitrosative stress, as occurs during aging, contributes

211 It protects various bacteria from nitrosative stress, but the mechanism is unknown.

212 ased neural histologic damage, oxidative and nitrosative stress, cytokine release, angiogenesis, and

213 , under aerobic conditions in the absence of nitrosative stress, elevated hmp expression increases S.

214 not protect Escherichia coli strains against nitrosative stress, even in a mutant devoid of NO-protec

215 h in the human host, including oxidative and nitrosative stress, high temperature, hypoxia, and nutri

216 In the presence of nitrosative stress, Hmp-deficient Salmonella exhibits re

217 misfolded proteins triggered by oxidative or nitrosative stress, or of mutated gene products.

218 ntributes to NO-dependent respiration during nitrosative stress, possibly conferring an advantage to

219 rfusion, LPS-induced inflammation, placental nitrosative stress, renal structural and functional alte

220 Conditions associated with oxidative or nitrosative stress, such as myocardial ischemia and repe

221 s cancer cells are particularly sensitive to nitrosative stress, these data open another path for the

222 2 antioxidant impairment, triggers oxidative/nitrosative stress, which also contributes to dendritic

223 ogen Porphyromonas gingivalis must withstand nitrosative stress, which is particularly high in the or

224 intestine indicative of basal oxidative and nitrosative stress, which was exacerbated by IR.

225 sium (5K apoptotic conditions), oxidative or nitrosative stress-induced OPA1 cleavage caused by compl

226 iaminedichloroplatinum (II), suggesting that nitrosative stress-induced suppression of Cdc25A primed

227 Our data suggest that nitrosative stress-mediated protein aggregation in neuro

228 and wild-type growth in bacteria undergoing nitrosative stress.

229 he metabolic stress imposed by oxidative and nitrosative stress.

230 the stringent response, sense oxidative and nitrosative stress.

231 than the brain on peripheral blood oxidative/nitrosative stress.

232 ed uteroplacental hemodynamics and placental nitrosative stress.

233 e transcriptional responses to oxidative and nitrosative stress.

234 primarily as a cytotoxic response to excess nitrosative stress.

235 ential to protect neurons from oxidative and nitrosative stress.

236 nd kill nonreplicating M. tuberculosis under nitrosative stress.

237 ers in protecting neurons from oxidative and nitrosative stress.

238 ade cerebral edema associated with oxidative-nitrosative stress.

239 P) exposed to agents that cause oxidative or nitrosative stress.

240 0893 (hcp) was abrogated in V2807 exposed to nitrosative stress.

241 g species are produced in nodules leading to nitrosative stress.

242 gested that it was mediated by oxidative and nitrosative stress.

243 lpha and PKC-beta and enhanced oxidative and nitrosative stress.

244 l fission and fusion induced by oxidative or nitrosative stress.

245 tiple AMPK-dependent pathways in response to nitrosative stress.

246 , such as elevated temperature and oxidative/nitrosative stress.

247 ive disorders mediated, at least in part, by nitrosative stress.

248 which Campylobacter may survive host-derived nitrosative stress.

249 signaling, as well as in protection against nitrosative stress.

250 as a mediator of neurotoxicity triggered by nitrosative stress.

251 cts on S. Typhimurium survival during innate nitrosative stress.

252 denitrosylation thus allows cells to survive nitrosative stress.

253 trite (ASN), a model system used to generate nitrosative stress.

254 ssion, consistent with its role in mediating nitrosative stress.

255 that growth of C. jejuni with nitrite causes nitrosative stress.

256 ork is a key responder to this oxidative and nitrosative stress.

257 cible components of a robust defence against nitrosative stress.

258 eudotuberculosis within the spleen following nitrosative stress.

259 e animals, suggesting elevated oxidative and nitrosative stress.

260 oter, which is also known to be sensitive to nitrosative stress.

261 bute to the pathophysiology of oxidative and nitrosative stress.

262 lyamines rescues growth of cad mutants under nitrosative stress.

263 ical role in defence of the bacillus against nitrosative stress.

264 the YjeB repressor is directly sensitive to nitrosative stress.

265 all of which are known to be upregulated by nitrosative stress.

266 R 3-component system, mediates resistance to nitrosative stress.

267 ing NO production and reducing oxidative and nitrosative stress.

268 mitochondrial oxidative stress, and promoted nitrosative stress.

269 iratory capacity and decreased oxidative and nitrosative stress.

270 ssion, which led to increased sensitivity to nitrosative stress.

271 by decreases in GSNOR activity, engendering nitrosative stress.

272 ide (NO) formation and greater oxidative and nitrosative stress.

273 tion restores NO formation, while preventing nitrosative stress.

274 , thus protecting cells against oxidative or nitrosative stress.

275 ing prolonged NO exposure or under oxidative/nitrosative stress.

276 nitrate, and HcpR2 regulates the response to nitrosative stress.

277 esponse to electron acceptor availability or nitrosative stress.

278 e adult mutant, signaling both oxidative and nitrosative stress.

279 g laccase, urease and growth under oxidative/nitrosative stress.

280 n species, allowing the bacteria to face the nitrosative stress.

281 sylation, and protein nitration, alleviating nitrosative stress.

282 mocytoma cell (PC12) models of oxidative and nitrosative stress.

283 teraction enables H. pylori to survive under nitrosative stress.

284 ciated with reduced myocardial oxidative and nitrosative stress.

285 RS, FleRS and CrdRS) in H. pylori respond to nitrosative stress.

286 h, at least in part, by triggering oxidative/nitrosative stress.

287 expression of OXPHOS subunits; oxidative and nitrosative stress; and oxidative DNA damage.

288 These data identify a nitrosative-stress signaling pathway that engages ATM an

289 on is an adaptive response to NO and related nitrosative stresses since Hmp levels are greatly elevat

290 ulosis SufB intein splicing to oxidative and nitrosative stresses when expressed in Escherichia coli.

291 staining, caspase-3 activity, oxidative and nitrosative stresses, and proinflammatory cytokine expre

292 TRPM7 channel activity causes oxidative and nitrosative stresses, producing cell rounding mediated b

293 ed a host of specialized mechanisms to evade nitrosative stresses, the cytochrome bd-I respiratory ox

294 ts C. neoformans from acidic, oxidative, and nitrosative stresses, which are encountered by the fungu

295 odulated by mild and transient oxidative and nitrosative stresses.

296 ritical for resistance to both oxidative and nitrosative stresses.

297 wn to be strongly inhibited by oxidative and nitrosative stresses.

298 transcriptional responses to these distinct nitrosative stresses.

299 ia into dormancy under extreme oxidative and nitrosative stresses.

300 nced susceptibility of CGNs to oxidative and nitrosative stressors.