ライフサイエンスコーパス: non-homologous end-joining

1 ends that are poor substrates for classical non-homologous end joining.

2 sed G overhang levels, and altered levels of non-homologous end joining.

3 repair by both homologous recombination and non-homologous end joining.

4 s of double-strand break repair generated by non-homologous end joining.

5 equent repair by homologous recombination or non-homologous end joining.

6 of chromosomal replication and DSB repair by non-homologous end joining.

7 r repairing DNA double-strand breaks through non-homologous end joining.

8 s: homologous recombination and Ku-dependent non-homologous end joining.

9 egulates the alternative DSB repair pathway, non-homologous end joining.

10 QLN4 overexpression represses HRR and favors non-homologous end joining.

11 through chromothripsis coupled to classical non-homologous end joining.

12 rimarily function in the DSB repair pathway, non-homologous end joining.

13 region of glsA, indicative of Cas9-directed non-homologous end joining.

14 epairing double-strand DNA breaks (DSBs) via non-homologous end joining.

15 gy near the breakpoints resembling repair by non-homologous end joining.

16 epaired by homologous recombination (HR) and non-homologous end-joining.

17 pe repair mechanism of hairpin formation and non-homologous end-joining.

18 nts now stemming from other repeats and from non-homologous end-joining.

19 participate in homologous recombination and non-homologous end-joining.

20 e homologous recombination (HR) or mutagenic non-homologous end-joining(1).

21 mosome fusions via the mutagenic alternative non-homologous end joining (A-NHEJ) pathway.

22 dent on Ku70/80 and LIG4, or the alternative non-homologous end-joining (A-NHEJ), which relies on PAR

23 EGFR mutation is associated with a defect in non-homologous end joining, a major pathway for DNA doub

24 ecombination, an error-free mechanism, or by non-homologous end joining, a process susceptible to int

25 )p53(-/-) MEFs, homologous recombination and non-homologous end-joining activities were significantly

26 on are predominantly mediated by alternative non-homologous end-joining activity that may employ eith

27 Alternative non-homologous end joining (alt-NHEJ) was originally ide

28 that errors in DNA repair pathways, such as non-homologous end joining and homologous recombination,

29 The TRF2-Rap1 complex suppresses non-homologous end joining and interacts with DNAPK-C to

30 e other five types of solid tumors, in which non-homologous end joining and microhomology end joining

31 ted stochastic model of DNA damage repair by non-homologous end joining and of gamma irradiation-indu

32 otein and combined deficiencies in classical non-homologous end joining and p53 predispose to RAG-ini

33 the choice of homologous recombination over non-homologous end joining and potentially other mutagen

34 revious studies have shown that 53BP1 is pro-non-homologous end-joining and anti-HR.

35 timated frequencies of accurate or mutagenic non-homologous end-joining and gene correction by homolo

36 ks between the target sequences, stimulating non-homologous end-joining and homologous recombination.

37 repair occurs in cells fully proficient for non-homologous end-joining and is not compensated by DNA

38 gulation, that BCCIP is unlikely to regulate non-homologous end joining, and that BCCIP plays a criti

39 ctionally contribute to efficient resection, non-homologous end joining, and tolerance to DNA-damagin

40 in the repair of DNA double-strand breaks by non-homologous end-joining, and by the discovery of a un

41 e found that MMSET is required for efficient non-homologous end joining as well as homologous recombi

42 ssay that is more sensitive than the typical non-homologous end joining assay.

43 RNF168 rescues 53BP1 recruitment involved in non-homologous end joining but not BRCA1 recruitment for

44 the interference of high LET radiation with non-homologous end joining but not homologous recombinat

45 mulation at DNA breaks is enhanced by active non-homologous end-joining but does not require DNA-PKcs

46 roach to reduce the toxicity associated with non-homologous end joining by promoting the use of homol

47 short palindromic repeats (CRISPR)/Cas9 and non-homologous end-joining by deleting the repeat region

48 iple cell lines, we found that the canonical non-homologous end joining (C-NHEJ) factor XLF promotes

49 mpared to HR, whereas Ku-dependent classical non-homologous end joining (C-NHEJ) has a minimal role t

50 Classic non-homologous end joining (C-NHEJ) is the predominant D

51 In mammalian cells, the 'classical' non-homologous end joining (C-NHEJ) pathway repairs both

52 ngly none of the components of the canonical non-homologous end joining (C-NHEJ) pathway were identif

53 Canonical non-homologous end joining (c-NHEJ) repairs DNA double-s

54 pair is usually facilitated by the classical non-homologous end joining (C-NHEJ), or homologous recom

55 deletion rearrangement mediated by canonical non-homologous end joining (C-NHEJ).

56 Classical non-homologous end-joining (C-NHEJ) is the dominant path

57 elomere fusions require either the classical non-homologous end-joining (C-NHEJ) pathway dependent on

58 Besides the KU-dependent classical non-homologous end-joining (C-NHEJ) pathway, an alternat

59 ng mechanisms, the main process is classical non-homologous end-joining (C-NHEJ) which relies on Ku b

60 or critical role in ICL repair was seen for non-homologous end-joining (cku-80) or base excision rep

61 a mutated (ATM); and inhibitors of classical non-homologous end joining (cNHEJ) and alternative end j

62 Classical non-homologous end joining (cNHEJ) and homologous recomb

63 ndependent function for LRF in the classical non-homologous end joining (cNHEJ) pathway of double-str

64 CC4-like factor (XLF) functions in classical non-homologous end-joining (cNHEJ) but is dispensable fo

65 catalytic subunit (DNA-PKcs), is a classical non-homologous end-joining (cNHEJ) factor(1).

66 estigate the interplay between Ku, a central non-homologous end-joining component, and the Mre11-Rad5

67 lta defects in Tel1/ATM kinase signaling and non-homologous end joining, consistent with the role of

68 sensitivity of haematopoietic stem cells to non-homologous end-joining deficiency is therefore a key

69 tivation of the p97-ATX3 complex affects the non-homologous end joining DNA repair pathway and hypers

70 de DNA end binding proteins required for the non-homologous end joining DNA repair pathway, increases

71 end joining (MMEJ) rather than the canonical non-homologous end joining DNA repair pathway.

72 ation (insertion or deletion) by error-prone non-homologous end joining DNA repairing.

73 protein NONO was found to be involved in the non-homologous end-joining DNA repair process and in pol

74 ns indicate that these have been mediated by non-homologous end-joining DNA repair, although varying

75 ile another chromosome break repair pathway, non-homologous end joining, does not affect chromosome s

76 sh that REV7 blocks DSB resection to promote non-homologous end-joining during immunoglobulin class s

77 We found Cas9-gRNA achieved 7-8x higher non-homologous end joining efficiencies (3%) than reTALE

78 fragment at the same time, thereby reducing non-homologous end joining efficiency.

79 in vivo genome editing method, combined with non-homologous end joining, enabling permanent chromosom

80 We find that inversion depends on the non-homologous end-joining enzyme LIG4.

81 This result suggests that non-homologous end-joining, even in haploid cells where

82 e the persistence of random integrations and non-homologous end-joining events.

83 t acetylation of H4 regulates binding of the non-homologous end joining factor 53BP1, which engages c

84 The authors demonstrate that the non-homologous end-joining factor XLF promotes the stabi

85 G2 shepherd the broken DNA ends to classical non-homologous end joining for proper repair, roles for

86 ting functional redundancy between Rad18 and non-homologous end joining for tolerance of oxidative DN

87 Hypomorphic mutations in the non-homologous end-joining gene DCLRE1C (encoding ARTEMI

88 hat is distinct from that found in classical non-homologous-end-joining-, H2ax-, Mdc1- and Atm-defici

89 ination (HR) and antagonizes 53BP1-dependent non-homologous end joining in S/G2 phase.

90 (DNA-PK), a crucial player in DNA repair by non-homologous end-joining in higher eukaryotes, consist

91 e repaired with a high level of precision by non-homologous end-joining in mammalian cells.

92 demonstrate the importance of TDP2-dependent non-homologous end-joining in protecting both gene trans

93 DNA repair towards faster and more accurate non-homologous end-joining, including in post-mitotic pr

94 Repair of DNA double-strand breaks (DSBs) by non-homologous end joining is critical for neural develo

95 A-dependent protein kinase (DNA-PK)-mediated non-homologous end joining is inhibited.

96 Non-homologous end joining is initiated by the associati

97 bioluminescence imaging, that the assay for non-homologous end-joining is sensitive, quantitative, r

98 SWI/SNF and RSC enzymes is inhibited by the non-homologous end-joining machinery, and that their rec

99 damage-tolerance in G(1) (because of back-up non-homologous end joining-mediated DSB repair), yet Rad

100 Micro-homology-mediated non-homologous end joining (MMEJ) can also be used but t

101 Non homologous end joining (NHEJ) is an important proces

102 The non homologous end-joining (NHEJ) pathway of double-stra

103 There is increased DNA mis-repair by non-homologous end joining (NHEJ) and both NHEJ and homo

104 DNA non-homologous end joining (NHEJ) and homologous recombi

105 re reported for translesion synthesis (TLS), non-homologous end joining (NHEJ) and homologous recombi

106 ain repair pathways used to resolve DSBs are Non-Homologous End Joining (NHEJ) and Homologous Recombi

107 promotes the two major DSB repair pathways, non-homologous end joining (NHEJ) and homologous recombi

108 ebrafish (Danio rerio) and livestock through non-homologous end joining (NHEJ) and homology-directed

109 trand break repair that buttresses canonical non-homologous end joining (NHEJ) and is manifest in NHE

110 Non-homologous end joining (NHEJ) and single-strand anne

111 Homology-directed repair and non-homologous end joining (NHEJ) are the two major DSB

112 HD1 is required for DNA damage signaling and non-homologous end joining (NHEJ) at unprotected telomer

113 Finally, I find that all non-homologous end joining (NHEJ) defective cells (wheth

114 XRCC4-like factor (XLF) is a non-homologous end joining (NHEJ) DNA double strand brea

115 d into end-to-end chromosome fusions via the non-homologous end joining (NHEJ) double-strand break re

116 Mammalian cells require non-homologous end joining (NHEJ) for the efficient repa

117 The repair of DSBs by non-homologous end joining (NHEJ) has been extensively s

118 ohomology-mediated end joining (MMEJ), while non-homologous end joining (NHEJ) has not been reported.

119 Initiation of HR in the G1 phase blocks non-homologous end joining (NHEJ) impairing DSB repair.

120 recognition site in the BRCT domain impairs non-homologous end joining (NHEJ) in cell.

121 DNA double-strand break (DSB) repair by non-homologous end joining (NHEJ) in human cells is init

122 Non-homologous end joining (NHEJ) involves limited proce

123 Non-homologous end joining (NHEJ) is a key cellular proc

124 Non-homologous end joining (NHEJ) is a major DNA double-

125 Non-homologous end joining (NHEJ) is a major pathway to

126 Non-homologous end joining (NHEJ) is critical for the ma

127 DNA double strand break (DSB) repair by non-homologous end joining (NHEJ) is initiated by DSB de

128 Non-homologous end joining (NHEJ) is the main repair pat

129 Non-homologous end joining (NHEJ) is the major model pro

130 Although non-homologous end joining (NHEJ) is the most used DSBs

131 Non-homologous end joining (NHEJ) is the predominant pat

132 m the RAG post-cleavage complex (PCC) to the non-homologous end joining (NHEJ) machinery to promote a

133 are non-recurrent and can be generated by a non-homologous end joining (NHEJ) mechanism.

134 capabilities; however, the preponderance of non-homologous end joining (NHEJ) mediated repair events

135 The available evidence indicates a role for non-homologous end joining (NHEJ) of DNA double-strand b

136 We hypothesize that inhibiting non-homologous end joining (NHEJ) or enhancing homology-

137 regulated process performed predominantly by non-homologous end joining (NHEJ) or homologous recombin

138 and breaks (DSBs) are repaired by either the non-homologous end joining (NHEJ) or homologous recombin

139 uble strand breaks (DSBs) can be repaired by non-homologous end joining (NHEJ) or homology-directed r

140 implicates breaks followed by repair through non-homologous end joining (NHEJ) or stalled fork repair

141 reaks that can undergo DNA repair either via non-homologous end joining (NHEJ) or, in the presence of

142 se IIIalpha is a component of an alternative non-homologous end joining (NHEJ) pathway for DNA double

143 The non-homologous end joining (NHEJ) pathway is used in div

144 referentially repaired using the error-prone non-homologous end joining (NHEJ) pathway.

145 R) while stymieing repair by the error-prone non-homologous end joining (NHEJ) pathway.

146 f microhomology in both alt-EJ and classical non-homologous end joining (NHEJ) remains unclear.

147 Inhibition of Non-Homologous End Joining (NHEJ) repair either pharmaco

148 We studied the impairment of the non-homologous end joining (NHEJ) repair pathway and DNA

149 kinase (DNA-PK) plays a critical role in the non-homologous end joining (NHEJ) repair pathway and the

150 While non-homologous end joining (NHEJ) repair results in vari

151 B-mediated homologous recombination (HR) and non-homologous end joining (NHEJ) repair systems, leadin

152 ught to arise from a moderate attenuation of non-homologous end joining (NHEJ) repair, the role of DE

153 sponses, including checkpoint activation and non-homologous end joining (NHEJ) repair.

154 Non-homologous end joining (NHEJ) repairs DNA double str

155 knockout MEFs exhibited distinct defects in non-homologous end joining (NHEJ) when compared to their

156 Here, we suggest a role of LKB1 in non-homologous end joining (NHEJ), a major DNA double-st

157 nit (DNA-PKcs) plays a key role in mediating non-homologous end joining (NHEJ), a major repair pathwa

158 Non-allelic homologous recombination (NAHR), non-homologous end joining (NHEJ), and microhomology-med

159 otes, DNA DSBs are predominantly repaired by non-homologous end joining (NHEJ), but DNA ends can also

160 for sequence-specific gene knockout through non-homologous end joining (NHEJ), but it remains ineffi

161 ir factors, in particular those required for non-homologous end joining (NHEJ), do not form discrete

162 non-allelic homologous recombination (NAHR), non-homologous end joining (NHEJ), fork stalling and tem

163 hen can become the substrate for error-prone non-homologous end joining (NHEJ), generating mutations

164 xcision repair (NER), mismatch repair (MMR), non-homologous end joining (NHEJ), homologous recombinat

165 Yeast Rap1 protects telomeres from non-homologous end joining (NHEJ), plays important roles

166 common DSB repair mechanism in human cells, non-homologous end joining (NHEJ), rejoins broken DNA en

167 ly detect homology-directed repair (HDR) and non-homologous end joining (NHEJ), respectively.

168 In contrast to non-homologous end joining (NHEJ), TMEJ efficiently repa

169 air by homologous recombination (HR) but not non-homologous end joining (NHEJ), using HeLa cell lines

170 s of either homologous recombination (HR) or non-homologous end joining (NHEJ), whereas SUMO2/3 was r

171 -strand breaks are repaired predominantly by non-homologous end joining (NHEJ), which directly ligate

172 tly reported the involvement of WT TDP-43 in non-homologous end joining (NHEJ)-mediated DSB repair, w

173 e Alb locus in mouse liver is mainly through non-homologous end joining (NHEJ)-mediated knock-in.

174 ch between homologous recombination (HR) and non-homologous end joining (NHEJ).

175 A repair: homology directed repair (HDR) and non-homologous end joining (NHEJ).

176 nt, while still protecting telomeres against non-homologous end joining (NHEJ).

177 DSBs), thereby influencing the efficiency of non-homologous end joining (NHEJ).

178 . patens mutants for DSB factors involved in non-homologous end joining (NHEJ).

179 switch recombination (CSR), are repaired by non-homologous end joining (NHEJ).

180 factor for DNA double-strand break repair by non-homologous end joining (NHEJ).

181 kinase holoenzyme (DNA-PK) in the process of non-homologous end joining (NHEJ).

182 bition induces a repair defect that involves non-homologous end joining (NHEJ).

183 repair from homologous recombination (HR) to non-homologous end joining (NHEJ).

184 breaks (DSBs) are predominantly repaired by non-homologous end joining (NHEJ).

185 itical for their proper joining by classical non-homologous end joining (NHEJ).

186 ed through homology-directed repair (HDR) or non-homologous end joining (NHEJ).

187 role in double-strand break (DSB) repair by non-homologous end joining (NHEJ).

188 for DSB repair: homologous recombination and non-homologous end joining (NHEJ).

189 CC4 (LX) complex, which functions during DNA non-homologous end joining (NHEJ).

190 y involving homologous recombination (HR) or non-homologous end joining (NHEJ).

191 inase, accumulate 53BP1 and are processed by non-homologous end joining (NHEJ).

192 pair DSBs: homologous recombination (HR) and non-homologous end joining (NHEJ).

193 ) through either homologous recombination or non-homologous end joining (NHEJ).

194 repair pathways competing with HDR, such as non-homologous end joining (NHEJ).

195 s, homology-directed recombination (HDR) and non-homologous end joining (NHEJ).

196 karyotic cells are predominantly repaired by non-homologous end joining (NHEJ).

197 that support single-strand break repair and non-homologous end joining (NHEJ).

198 insights into LINP1's ability to facilitate non-homologous end joining (NHEJ). We characterized LINP

199 e repair of DNA double-strand breaks (DSBs): non-homologous end-joining (NHEJ) and homologous recombi

200 Non-homologous end-joining (NHEJ) and homologous recombi

201 Non-homologous end-joining (NHEJ) and homologous recombi

202 s) are repaired by two principal mechanisms: non-homologous end-joining (NHEJ) and homologous recombi

203 ase II (TOP2) are rejoined by TDP2-dependent non-homologous end-joining (NHEJ) but whether this promo

204 TRADD facilitates non-homologous end-joining (NHEJ) by recruiting NHEJ rep

205 tional error-prone pathway of DSB repair via non-homologous end-joining (NHEJ) catalysed by Ku and DN

206 to be associated with the components of the non-homologous end-joining (NHEJ) complex and participat

207 rate that combined inactivation of the XRCC4 non-homologous end-joining (NHEJ) DNA repair gene and p5

208 Allele-specific gene disruption induced by non-homologous end-joining (NHEJ) DNA repair offers a po

209 HDR) is limited by the competing error-prone non-homologous end-joining (NHEJ) DNA repair pathway.

210 GE syndrome, as an integral component of the non-homologous end-joining (NHEJ) DSB repair pathway.

211 As the non-homologous end-joining (NHEJ) factor, Ku70/80 (Ku),

212 Non-homologous end-joining (NHEJ) is a critical error-pr

213 chanisms for DSB repair; in mammalian cells, non-homologous end-joining (NHEJ) is a major DSB repair

214 Non-homologous end-joining (NHEJ) is the most prominent

215 The alternative non-homologous end-joining (NHEJ) machinery facilitates

216 that inactivating terminal components of the non-homologous end-joining (NHEJ) machinery or of the BR

217 ge response pathways, and promotes efficient non-homologous end-joining (NHEJ) of dysfunctional telom

218 DSBs are repaired by either error prone non-homologous end-joining (NHEJ) or error-free homologo

219 the X family that has been implicated in the non-homologous end-joining (NHEJ) pathway during repair

220 y (CHO) cell lines that are defective in the non-homologous end-joining (NHEJ) pathway of DNA double-

221 The non-homologous end-joining (NHEJ) pathway repairs DNA do

222 roduction of insertion-deletions (INDELs) by non-homologous end-joining (NHEJ) pathway underlies the

223 DNA fragments, which are not repaired by the non-homologous end-joining (NHEJ) pathway.

224 depleting HP1 from cells did not affect the non-homologous end-joining (NHEJ) pathway: instead it el

225 ed via the single-strand annealing (SSA) and non-homologous end-joining (NHEJ) pathways in a manner d

226 Non-homologous end-joining (NHEJ) plays an important rol

227 osomes and generate genome rearrangements by non-homologous end-joining (NHEJ) processes in specializ

228 dation of a novel assay to measure mutagenic non-homologous end-joining (NHEJ) repair in living cells

229 In contrast, alleles created by non-homologous end-joining (NHEJ) repair of double-stran

230 NA breaks are processed and repaired via the non-homologous end-joining (NHEJ) repair pathway.

231 homology directed repair (HDR) and decreased non-homologous end-joining (NHEJ) repair, suggesting tha

232 efficiency, which are typically repaired by non-homologous end-joining (NHEJ) resulting in nonspecif

233 a DNA nuclease that plays important roles in non-homologous end-joining (NHEJ), a major double-strand

234 Here we report a novel role of non-homologous end-joining (NHEJ), a pathway of double-s

235 Non-homologous end-joining (NHEJ), a repair process pred

236 n (HR) repair with a concomitant decrease in non-homologous end-joining (NHEJ), accounting for the im

237 Metnase promotes non-homologous end-joining (NHEJ), and knockdown causes

238 e between high-fidelity (HF) and error-prone non-homologous end-joining (NHEJ), as well as between pr

239 syl-DNA phosphodiesterase 2 (TDP2)-dependent non-homologous end-joining (NHEJ), but whether this proc

240 DNA-PKcs; encoded by PRKDC) functions in DNA non-homologous end-joining (NHEJ), the major DNA double

241 Since mammalian cells can repair DSBs by non-homologous end-joining (NHEJ), we hypothesized that

242 Finally, we extend this non-homologous end-joining (NHEJ)-based technique by dir

243 ever, mutagenic events caused by error-prone non-homologous end-joining (NHEJ)-mediated repair are in

244 ce between homologous recombination (HR) and non-homologous end-joining (NHEJ)-mediated repair.

245 repaired predominantly in mammalian cells by non-homologous end-joining (NHEJ).

246 tic opening before their repair by classical non-homologous end-joining (NHEJ).

247 DNA double-strand breaks (DSBs) repaired by non-homologous end-joining (NHEJ).

248 tion of DNA end-resection, and DSB repair by non-homologous end-joining (NHEJ).

249 NA damage being channelled through repair by non-homologous end-joining (NHEJ).

250 trand break (DSB) repair pathways, including non-homologous end-joining (NHEJ).

251 echanisms, homologous-recombination (HR) and non-homologous-end-joining (NHEJ).

252 breakpoint junctions revealed signatures of non-homologous end-joining, non-allelic homologous recom

253 repair (HR), while counteracting error-prone non-homologous end joining of DNA double-strand breaks.

254 poration, and it efficiently participates in non-homologous end joining of double-strand DNA breaks.

255 7 or its adapters impairs Ku80 removal after non-homologous end joining of DSBs.

256 ther demonstrate that the excursions promote non-homologous end joining of dysfunctional telomeres an

257 derived hiPSCs where successful deletion and non-homologous end joining of up to 725 kb reframed the

258 SceI-induced break can be repaired either by non-homologous end joining or by recombination between t

259 A double-strand breaks can be eliminated via non-homologous end joining or homologous recombination.

260 wed by repair through either the error-prone non-homologous end joining or the homology directed repa

261 DSBs are repaired by non-homologous end-joining or homology directed repair (

262 tid means that repair of DSBs occurs through non-homologous end-joining or microhomology-mediated end

263 s in a G1-like DNA repair mode which favours non-homologous end joining over interchromosomal recombi

264 double-strand DNA break (DSB) repair via the non-homologous end joining pathway, as unrepaired DSBs a

265 DNA-PKcs, which is integral to the non-homologous end joining pathway, thus negatively regu

266 an be further improved by suppression of the non-homologous end joining pathway.

267 uble strand breaks, initiating repair by the non-homologous end joining pathway.

268 B) repair as the underlying mechanism of the non-homologous end joining pathway.

269 s expressing BCR-ABL1 utilize an alternative non-homologous end-joining pathway (ALT NHEJ) to repair

270 amage response (DDR) and instrumental in the non-homologous end-joining pathway (NHEJ) used to detect

271 rrow failure syndrome) codes for a canonical non-homologous end-joining pathway factor, that the RNA

272 leotides during gap-filling synthesis in the non-homologous end-joining pathway of double-strand brea

273 As a member of the non-homologous end-joining pathway, it is also involved

274 ch as those encountered by pol lambda in the non-homologous end-joining pathway, may have been solved

275 in the proximity of the break were due to a non-homologous end-joining pathway, while larger deletio

276 in E. dermatitidis through disruption of the non-homologous end-joining pathway, with three individua

277 in repairing DNA double-strand breaks by the non-homologous end-joining pathway.

278 telomeres to protect them from engaging the non-homologous end-joining pathway.

279 h recombination use overlapping but distinct non-homologous end joining pathways to repair DNA double

280 proteins of the homologous recombination and non-homologous end joining pathways.

281 This overexpression triggers SSB repair and non-homologous end-joining pathways to increase DNA repa

282 involved defective base excision repair and non-homologous end-joining, pathways required for repair

283 itro analyses suggest that in the absence of non-homologous end joining proteins, L1 elements may uti

284 the processing of dysfunctional telomeres by non-homologous end joining, putatively through stabiliza

285 ble-stranded DNA and helps to facilitate the non-homologous end-joining reaction.

286 r shown to have homologous recombination and non-homologous end joining related activities and also t

287 led to enhanced phosphorylation of DNA-PK, a non-homologous end joining repair protein, in Hec-108 ce

288 Non-homologous end joining repair-based BCL11A enhancer

289 Wnt signalling enhances non-homologous end-joining repair in CRC, which is media

290 Although DNA non-homologous end-joining repairs most DNA double-stran

291 at take part in homologous recombination and non-homologous end joining, respectively, were transcrip

292 A DSB repair by homologous recombination and non-homologous end joining, respectively.

293 t provides DNA ligase activity for classical non-homologous end joining (the predominant DNA double-s

294 e heterodimer Ku70/Ku80, has a major role in non-homologous end joining-the main pathway in mammals u

295 a novel component regulating the switch from non-homologous end-joining to homologous recombination.

296 double-strand break repair switches from DNA non-homologous end-joining to homologous recombination.

297 ribution of DNA ligase 4-dependent classical non-homologous end-joining to long-range inter-chromosom

298 functions of DNA ligase 1 in replication and non-homologous end-joining uniquely position and capacit

299 removal of histone H3 from the genome during non-homologous end joining was promoted by both ATM and

300 In addition to non-homologous end joining, we detect signatures of repl