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1 nisms that could enable engineering of novel non-ribosomal peptide synthetases.
2 otryptophan represents a novel substrate for non-ribosomal peptide synthetases.
3 umarate:coenzyme A ligases, luciferases, and non-ribosomal peptide synthetases.
5 mproved substrate specificity prediction for non-ribosomal peptide synthetase adenylation domains bas
6 ly strict substrate specificities of related non-ribosomal peptide synthetase adenylation enzymes.
8 is synthesized in part by enzymes resembling non-ribosomal peptide synthetases and that the ABC trans
13 ynthase to a separate carrier protein, and a non-ribosomal peptide synthetase condensation domain con
15 Curacin A is a polyketide synthase (PKS)-non-ribosomal peptide synthetase-derived natural product
19 tations that upregulate transcription of the non-ribosomal peptide synthetase gene required for nidul
20 e diversification of polyketide synthase and non-ribosomal peptide synthetase genes from two newly de
23 non-ribosomal peptide and hybrid polyketide-non-ribosomal peptide synthetases, including those respo
25 suggests that AcsD and other members of the non-ribosomal peptide synthetase-independent siderophore
27 diction software, TxtB was identified as the non-ribosomal peptide synthetase module specific for 4-n
28 ached to CmaD through the actions of CmaA, a non-ribosomal peptide synthetase module, and CmaE, an un
29 Thaxtomin A is produced by the action of two non-ribosomal peptide synthetase modules (TxtA and TxtB)
30 cluding the expected polyketide synthase and non-ribosomal peptide synthetase modules and tailoring g
31 escribe the structures of two different holo-non-ribosomal peptide synthetase modules, each revealing
32 n this model, VbsS, which is similar to many non-ribosomal peptide synthetase multienzymes, has a cen
33 iously identified but experimentally elusive non-ribosomal peptide synthetase (NRPS) and NRPS-polyket
34 elating cyclic hexapeptides are assembled by non-ribosomal peptide synthetase (NRPS) enzymes remains
35 ge of an L-Pro-L-Trp dipeptide from the MalG non-ribosomal peptide synthetase (NRPS) followed by reve
36 are biosynthesized by a single multi-domain non-ribosomal peptide synthetase (NRPS) gene cluster.
37 e approach were applied to the known PKS and non-ribosomal peptide synthetase (NRPS) gene clusters in
38 hotransferase self-resistance gene (vph) and non-ribosomal peptide synthetase (NRPS) gene probes ampl
39 The initial stages of the pathway involve non-ribosomal peptide synthetase (NRPS) mediated assembl
41 tion of specialized metabolites derived from non-ribosomal peptide synthetase (NRPS) or polyketide sy
42 been proposed to require only the two-module non-ribosomal peptide synthetase (NRPS) peramine synthet
43 study, we determined the function of a novel non-ribosomal peptide synthetase (NRPS) system carried b
45 ve combination of polyketide synthase (PKS), non-ribosomal peptide synthetase (NRPS), and shikimate p
48 In vitro assays reveal two single-module non-ribosomal peptide synthetases (NRPs) that incorporat
49 -CoA synthetases, the adenylation domains of non-ribosomal peptide synthetases (NRPS), and firefly lu
51 The peptide backbone of PVD is assembled by non-ribosomal peptide synthetases (NRPSs) and modified b
55 ide-derived natural products are produced by non-ribosomal peptide synthetases (NRPSs) in an assembly
56 teins termed polyketide synthases (PKSs) and non-ribosomal peptide synthetases (NRPSs) that contain r
57 y, the nocardicin A gene cluster encodes two non-ribosomal peptide synthetases (NRPSs), NocA and NocB
61 ical protein and has no sequence homology to non-ribosomal peptide synthetase or bacterial cyclodipep
62 and peptide-polyketide siderophores involves non-ribosomal peptide synthetase, polyketide synthase an
63 organization of the nos synthetase, a mixed non-ribosomal peptide synthetase-polyketide synthase, is
64 mutations in ausA, encoding the aureusimine non-ribosomal peptide synthetase, reduced S. aureus cyto
65 Here we show that communication between two non-ribosomal peptide synthetase subunits responsible fo
66 osynthetic gene clusters for uncharacterised non-ribosomal peptide synthetases, suggesting a high div
68 s are synthesized from a classically derived non-ribosomal peptide synthetase tripeptide (from delta-
70 und that expression of nrps1 which encodes a non-ribosomal peptide synthetase was elevated in the omp
71 ding the structural basis for catalysis with non-ribosomal peptide synthetases will facilitate bioeng
72 ed by the action of polyketide synthases and non-ribosomal peptide synthetases with unusual domain st