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1 s FFA2-selective, whereas propionate (C3) is non-selective.
2 E) that converted the pore from chloride- to non-selective.
4 have the behavioral toxicity associated with non-selective 5-HT2 receptor agonists, targeting the 5-H
5 c footprint, but the peripheral spread stays non-selective-a surprising finding given a number of ana
6 sorption, while an ultra-thin metal film has non-selective absorption in the near infrared wavelength
7 d with drug-eluting stents may be due to the non-selective actions of antimitogenic drugs on endothel
10 ird and 8-sulphophenyltheophylline (8-SPT; a non-selective adenosine receptor antagonist) before the
13 S-21680 (1.0-10.0 micromol/kg, i.p.) and the non-selective agonist, N(6)-ethylcarboximidoadenosine (N
16 licits feeding, (2) prior treatment with the non-selective AMPA/KAR antagonist, CNQX, suppresses ATPA
17 Further, LH pretreatment with either the non-selective AMPAR/KAR antagonist, 6-cyano-7-nitroquino
20 Single-cell RNA sequencing demonstrated a non-selective and multi-cellular gene expression pattern
22 (OPG) GEM model, we report novel defects in non-selective and selective attention without an accompa
24 syntheses of primary amines, which often are non-selective and suffer from over-alkylation and reduct
25 and more consistently produced than with the non-selective antagonist gabazine, and both were blocked
26 (PET) dopamine subtype 2/3 receptor (D2/3R) non-selective antagonist tracers suggests that obese (OB
27 r dimer population, but the receptor subtype non-selective antagonists atropine and N-methylscopolami
33 Depletion of this essential nutrient induces non-selective autophagy by inhibiting TORC1, leading to
37 zepine receptor partial agonist MRK-696, and non-selective benzodiazepine receptor full agonists, mid
38 ng compounds were compared with those of the non-selective benzodiazepine receptor partial agonist MR
39 ay promote mild bronchodilation that offsets non-selective beta blockade-induced bronchoconstriction
42 s of the beta-adrenergic agents propranolol (non-selective beta-antagonist) and salbutamol (beta(2)-a
44 e variability of physicians' preferences for non-selective beta-blockers (BBs) and endoscopic varicea
45 Recent evidence cautions against the use of non-selective beta-blockers (NSBB) in patients with refr
46 ysine (NTA) and deactivating agents to block non-selective binding between GO-NTA sheets and non-targ
47 Polycystin-2 (PC2), the PKD2 protein, is a non-selective Ca(2+)-permeable cation channel which may
48 In addition, we show that GLR genes encode non-selective Ca(2+)-permeable channels that can regulat
52 187 (1 microM), to activate Ca(2+)-activated non-selective cation (NSC) channels (T84 cells) and larg
55 l Melastatin 3 (TRPM3) is a Ca(2+) permeable non-selective cation channel activated by heat and chemi
56 al vanilloid 1 (TRPV1) is a Ca(2+) permeable non-selective cation channel activated by physical and c
57 rophysiological recordings show that it is a non-selective cation channel and that its activity depen
58 These effects could be prevented with the non-selective cation channel blocker Gadolinium (Gd(3+))
61 ential channel vanilloid type 1 (TRPV1) is a non-selective cation channel expressed in sensory neuron
64 bed a constitutively active, Ca2+-permeable, non-selective cation channel in freshly dispersed rabbit
65 ribed a constitutively active Ca2+-permeable non-selective cation channel in freshly dispersed rabbit
67 al canonical 5 (TRPC5), a calcium-permeable, non-selective cation channel is expressed in the periphe
70 4,5-bisphosphate (PtdIns(4,5)P2) -modulated, non-selective cation channel that belongs to the family
71 Transient receptor potential 7 (TRPC7) is a non-selective cation channel that can be activated by bo
72 stin-2 (PC2) is a TRP-type, Ca(2+)-permeable non-selective cation channel that plays an important rol
74 potential vanilloid 1 (TRPv1) receptor is a non-selective cation channel that serves as a marker of
75 Localization and function of the polymodal non-selective cation channel TRPV1 (transient receptor p
76 ctance and then activates a Na(+)-permeable, non-selective cation channel via depolarization-induced
77 opening of a cyclic nucleotide-gated (CNG), non-selective cation channel which depolarizes the cells
78 ted that WT ML1 is a multiple subconductance non-selective cation channel whose function is inhibited
79 tery myocytes ET-1 evokes a Ca(2+)-permeable non-selective cation channel with properties similar to
80 re, we show that DmPiezo, a Ca(2+)-permeable non-selective cation channel, functions as an intrinsic
82 2l1 or Pkdl), encoding polycystin-L (PCL), a non-selective cation channel, increases neuronal excitab
89 as Ca(2+)-activated Cl() channels (CaCC) and non-selective cation channels (NSCC) have been suggested
90 act with and regulate members of a family of non-selective cation channels (TRPC) which have been sug
93 Receptor Potential Canonical 4 (TRPC4) forms non-selective cation channels activated downstream from
94 RPC4 proteins function as Ca(2+) conducting, non-selective cation channels in endothelial, smooth mus
95 transient receptor potential (TRP) family of non-selective cation channels in murine megakaryocytes f
96 tion-activated cyclic nucleotide-gated (HCN) non-selective cation channels in neurons carry currents
97 f the transient receptor potential family of non-selective cation channels is a polymodal nociceptor.
98 egarding Cl(-) channels in the ER/SR and the non-selective cation channels or putative 'Ca(2+) leak c
99 regarding Cl- channels in the ER/SR and the non-selective cation channels or putative 'Ca2+ leak cha
101 ogical and pharmacological properties of the non-selective cation channels stimulated by the physiolo
102 d-aspartate (NMDA) receptors are heteromeric non-selective cation channels that require the binding o
103 ntial (TRP) superfamily comprises a group of non-selective cation channels that sense and respond to
104 (TRPM7) channels are novel Ca(2+)-permeable non-selective cation channels ubiquitously expressed.
112 extracellular Ca(2+); (ii) large conductance non-selective cation channels; and (iii) Ca(2+)-dependen
113 ing a constitutively active Ca(2+)-permeable non-selective cation conductance (I(cat)) in rabbit ear
114 cid, an antagonist for the calcium-activated non-selective cation conductance (ICAN ) abolished the e
116 (GSK), a TRPV4 channel agonist, activated a non-selective cation conductance that coupled to activat
117 This is accompanied by up-regulation of a non-selective cation conductance with TRPM4-like propert
118 mic acid, a blocker of the calcium-activated non-selective cation conductance, abolished the effect o
119 s the cell by recruiting a calcium-activated non-selective cation current (ICAN) capable of generatin
120 , as well as a mechanically-sensitive inward non-selective cation current characteristic of Piezo2.
121 of cells expressing TRPC1+STIM1 activated a non-selective cation current, I(SOC), that was blocked b
122 -acetyl-sn-glycerol (OAG) stimulated similar non-selective cation currents and Ca2+ entry in HSY cell
123 ading to the postulation that post-traumatic non-selective cation currents are determined by TRPM4/SU
124 cells, arginine-vasopressin (AVP) activated non-selective cation currents associated with TRPC6 acti
125 ne of these evoked robust Ca(2+)-signals and non-selective cation currents, the other weaker Ca(2+)-s
127 These currents are produced by relatively non-selective, cation-permeable channels or pores in the
128 5 (TRPC5) is a subunit of a Ca(2+)-permeable non-selective cationic channel which negatively regulate
129 ezo proteins as subunits of Ca(2+)-permeable non-selective cationic channels for detection of noxious
130 ponsible for flow-sensitive non-inactivating non-selective cationic channels which depolarize the mem
131 [Formula: see text]) and a calcium-activated non-selective cationic current ([Formula: see text])-wer
133 used biomarker of neuroinflammation, but its non-selective cellular expression pattern implies roles
134 n decrease unitary conductance and produce a non-selective channel while the presence of a positive c
135 nt MPV17 to reveal that this protein forms a non-selective channel with a pore diameter of 1.8 nm and
137 tribution of reaction intermediates, and (4) non-selective chemistry leading to the production of mul
139 avenous infusion of saline (placebo) and the non-selective competitive nitric oxide synthase inhibito
140 state duplication frequencies measured under non-selective conditions (10(-4) to 10(-5) ) confirmed t
142 of genomic sequences targeted by T-DNA under non-selective conditions were similar to those of random
144 restin itself possesses a stretch-sensitive, non-selective conductance that is largest in the presenc
145 tracellular chloride is a stretch-sensitive, non-selective conductance within the lateral membrane, G
147 ol), a non-specific NO synthase inhibitor, a non-selective COX inhibitor or combined inhibition durin
148 roup subset received 100 mg of indomethacin (non-selective COX-1 and COX-2 inhibitor), and another HS
150 Here, we described an outward rectifying non-selective current mediated by a TRP ion channel in i
151 lia also revealed TRPM4-like, Ca2+-activated non-selective currents (I CAN) with an EC50 of 1.2 micro
152 G-monomethyl-l-arginine (l-NMMA, 10 mm), the non-selective cyclooxygenase inhibitor ketorolac trometh
158 e during sessions with good avoidance but is non-selective during poor avoidance, with high release c
159 ive thermal emitter as compared to that of a non-selective emitter at night, and 5 degrees C sub-ambi
163 e of nematicides, but many of them including non-selective fumigants have been phased out, particular
165 subtypes in the memory-impairing effects of non-selective GABAAR PAMs has not been fully elucidated.
166 are primarily involved in the impairment, by non-selective GABAAR PAMs, of visual recognition and vis
169 howing efficacy of sarcosine, an endogenous, non-selective glycine-reuptake inhibitor mediated by Gly
171 (intrathecal) injection of carbenoxolone (a non-selective hemichannel blocker) and selective connexi
172 er sos1 mutants more tolerant to paraquat, a non-selective herbicide causing oxidative stress, indica
173 we examine the tolerability and efficacy of non-selective HTT lowering with an AAV5 encoded miRNA ta
177 two hypotheses: that stress would lead to a non-selective increase in the expression of Pavlovian bi
178 cker, improves the clinical outcome, whereas non-selective inhibition of both forms of tumour necrosi
179 e of PDE7A1 catalytic domain in complex with non-selective inhibitor 3-isobutyl-1-methylxanthine and
183 portion of posterior telencephalon receives non-selective, interspersed inputs from all glomeruli, w
185 nt receptor potential ankyrin 1 (TRPA1) is a non-selective ion channel, which is expressed in nocicep
186 F has been reported as a cation-, anion-, or non-selective ion channel, without a definite conclusion
187 ular, monovalent cation transporters such as non-selective ion channels and cation:proton antiporters
188 hannels defines a new family of functionally non-selective ion channels, and also provides important
191 BA(A) receptor agonist) or kynurenic acid (a non-selective ionotropic glutamate receptor antagonist)
198 by selective agonism of MC(1), not shared by non-selective ligands, and dependent on downstream ERK1/
201 sphingosine 1-phosphate (S1P) receptors in a non-selective manner decreases disease activity in patie
203 The samples were enumerated on selective and non-selective media and on doxycycline (4 microg/ml) med
204 cterisation of a novel group of functionally non-selective members of the prokaryotic 'inward rectifi
207 tamate receptor mGluR5) and 10 mum LY341495 (non-selective mGluR blocker), but not by 80 mum AP5 (NMD
208 V1, and decreased visual information, while non-selective mice have decreased noise correlations in
211 epths, implying that reconstructions using a non-selective mixture of morphotypes could potentially b
214 Indatraline is an antidepressive agent and a non-selective monoamine transporter inhibitor that block
222 Because deficiency of sodium leak channel, non-selective (Nalcn) causes lethal apnea in humans and
223 ssense mutations in the sodium leak channel, non-selective (NALCN) in four families affected by CLIFA
225 l lobe and type II neuroblasts compared with non-selective neuroblasts, neurons and glia revealed a r
226 viorally relevant ensembles by activation of non-selective neurons decreased performance, whereas act
227 ls, are often simplified as a single pool of non-selective neurons lacking connection specificity.
229 cotinic antagonist methyllycaconitine or the non-selective nicotinic antagonist mecamylamine indicate
230 after intra-peritoneal administration of the non-selective nitric oxide synthase (NOS) inhibitor, N(G
231 tension as does systemic administration of a non-selective nitric oxide synthase (NOS) inhibitor.
233 ad any of three clinically important errors: non-selective non-steroidal anti-inflammatory drugs (NSA
234 Cyclo-oxygenase-2 selective inhibitors and non-selective non-steroidal anti-inflammatory drugs (NSA
235 uld reduce ulcer complications compared with non-selective non-steroidal anti-inflammatory drugs, but
236 nitro-l-arginine methyl ester hydrochloride (non-selective NOS inhibitor); (3) 5 mm N-propyl-l-argini
238 CVC at eNOS-inhibited (41 +/- 3%CVCmax) and non-selective NOS-inhibited (40 +/- 4%CVCmax) sites were
240 cantly less likely to have been prescribed a non-selective NSAID if they had a history of peptic ulce
241 2 inhibitors and aspirin than in those using non-selective NSAIDs and aspirin; significantly fewer un
242 sion that COX-2 inhibitors are preferable to non-selective NSAIDs in patients with chronic pain and c
243 exposure to cyclo-oxygenase 2 selective and non-selective NSAIDs was compared with remote exposure t
244 vascular effects but concern also relates to non-selective NSAIDs, especially those with strong COX2
246 ited to COX-2 selective but also extended to non-selective NSAIDs, such as Diclofenac and Ketoprofen.
250 with different selective drugs in respect to non-selective ones, most of them are only able to delay
253 The purpose of this study was to assess a non-selective opioid receptor agonist, biphalin, in decr
255 ile, intrathecal pretreatment with naloxone, non-selective opioid receptor antagonist, did not affect
258 xpressed human rod opsin, driven by either a non-selective or ON-bipolar cell-specific promoter, can
261 Our data suggest that claudin-16 forms a non-selective paracellular cation channel, rather than a
262 n effect replicated pharmacologically with a non-selective PDE4 inhibitor, implicating cAMP signaling
264 4 evolved by recruitment and adaptation of a non-selective phosphodiesterase and a matrix component i
269 tide inhibitor of calcineurin (CaN-AIP); the non-selective PP1/PP2A inhibitors okadaic acid (0.5, 10,
271 smolytes, proposedly due to the opening of a non-selective protein channel of unknown molecular ident
272 ical analyses imply that CsgG is an ungated, non-selective protein secretion channel that is expected
273 nal poly(IC) exposure and treatment with the non-selective purinergic antagonist suramin to test the
276 ockade of CRH receptors in the mPFC with the non-selective receptor antagonist d-Phe-CRH (50 ng or 10
277 ical fluid extraction (SFE) were applied for non-selective recovery of peppermint lipophilic extracts
278 vantages including the premature leakage and non-selective release of photosensitizers still exist.
284 ght a slight shift in prescribing toward the non-selective serotonin reuptake inhibitor bupropion hyd
285 ory, unintended declines in case finding and non-selective serotonin reuptake inhibitor substitute tr
287 ) agonists (ERalpha /PPT or ERbeta: DPN); or non-selective sex hormone receptor antagonists (ER/ICI 1
288 Both face-selective and face-active but non-selective sites showed a posterior to anterior gradi
290 t mechanisms of miRNA sorting (selective and non-selective), suggesting that sorting occurs via funda
291 tions and long reaction times, often causing non-selective sulphation at different and/or multiple hy
294 s of the NaK channel from Bacillus cereus, a non-selective tetrameric cation channel, in its Na+- and
297 in DRG neurones, which was attenuated by the non-selective TRP channel antagonist ruthenium red (10 m