ライフサイエンスコーパス: nonallergic

1 re positive (allergic) and 29 were negative (nonallergic).

2 less frequently non-IgE-mediated allergy or nonallergic.

3 d hay fever, suggesting that pathways may be nonallergic.

4 se label of drug allergic and false label of nonallergic.

5 sponses at 24 h were similar in both groups (nonallergic, 110 +/- 24 eosinophils/mm2; allergic, 113 +

6 for asthma among adolescents, especially for nonallergic adolescents and those exposed to maternal sm

7 d IL-4 synthesis both in T cells from normal nonallergic adult subjects as well as in naive T cells f

8 f this resistance is preserved in nonatopic, nonallergic adults and is unmasked during exposure to an

9 of resistance to HDM challenge in nonatopic, nonallergic adults was muted T-cell activation in the pe

10 n of irritants may facilitate development of nonallergic AHR.

11 The role of the Nlrp3 inflammasome in nonallergic airway hyperresponsiveness (AHR) has not pre

12 eq) of the nasal epithelium was performed on nonallergic and house dust mite-allergic AR patients to

13 Seventy-two children were nonallergic and nonsensitized.

14 sophagitis, with a more pronounced effect in nonallergic and younger individuals, especially in the p

15 in RV strain 1B-infected naive BALB/c mice (nonallergic) and identified CCL7 and IFN regulatory fact

16 is classified into allergic asthma (AA) and nonallergic asthma (NA), yet both are treated identicall

17 Increased risks were observed for nonallergic asthma (OR 1.80; 95% CI 1.27-2.55) and rhini

18 : eosinophilic allergic asthma, eosinophilic nonallergic asthma and noneosinophilic nonallergic asthm

19 Children with nonallergic asthma had lower dihydroceramides, ceramides

20 t gain (GWG), with incidence of allergic and nonallergic asthma in offspring.

21 Allergic and nonallergic asthma severity in children can be affected

22 Our goal was to understand the mechanism of nonallergic asthma that leads to airway hyperreactivity

23 er, the association of maternal obesity with nonallergic asthma was observed in boys (2.39, 1.40-4.09

24 When we evaluated allergic versus nonallergic asthma, neopterin levels tended to be associ

25 e lectin pathway of complement activation in nonallergic asthma.

26 d sphingomyelins compared with children with nonallergic asthma.

27 LS, capable of differentiating allergic from nonallergic asthma.

28 spiratory phenotypes, including allergic and nonallergic asthma.

29 hilic nonallergic asthma and noneosinophilic nonallergic asthma.

30 eopterin levels tended to be associated with nonallergic asthma.

31 in AA Treg compared with healthy control and nonallergic asthmatic counterparts.

32 n, mild-to-moderate allergic asthmatics, and nonallergic asthmatics.

33 have altered progenitor capacity compared to nonallergic basal cells.

34 e major bee venom allergen PLA isolated from nonallergic beekeepers show increased expression of IL-1

35 0.1 kUa/L discriminated between allergic and nonallergic best (AUC, 0.96; sensitivity, 94%; specifici

36 No eosinophil infiltrate was observed in nonallergic biopsies at 30 min and 6 h, whereas signific

37 py, as well as their increased expression in nonallergic but high-dose allergen-exposed beekeepers.

38 ere accurately classified into allergics and nonallergics by the Hoxb8 MAT.

39 et al. establish a clear association between nonallergic childhood asthma, lower whole-blood sphingol

40 8) from 52 highly characterized allergic and nonallergic children (0.5-17 years) with severe treatmen

41 ase had more epilepsy in their lifetime than nonallergic children (logistic regression, adjusted odds

42 olerant (P < .001) and non-peanut-sensitized nonallergic children (P < .001).

43 ower neonatal T-cell PKCzeta expression than nonallergic children (P < 0.001).

44 he effect of being overweight was greater in nonallergic children (RR = 1.77, 95% CI: 1.26, 2.49) tha

45 lla, and Coprococcus in allergic compared to nonallergic children from infancy to school age.

46 children with atopic dermatitis and healthy nonallergic children in rural and urban settings from th

47 of age had lower cord blood BAFF levels than nonallergic children.

48 alence among allergic children but not among nonallergic children.

49 ased risk of new-onset asthma in boys and in nonallergic children.

50 4 levels and POIT but not from nonsensitized nonallergic children.

51 nce of published systematic reviews (SRs) on nonallergic comorbidities of atopic eczema (AE).

52 Seasonality of clinical diagnoses of nonallergic conjunctivitis among the 4143 patients (2364

53 n to compare demographics and seasonality of nonallergic conjunctivitis with allergic conjunctivitis.

54 Weekly total clinical diagnoses at UCSF of nonallergic conjunctivitis, allergic conjunctivitis, gla

55 different in allergic subjects from that in nonallergic control subjects (deltaPD20 = -0.40 versus -

56 Thirteen nonallergic control subjects were also assessed.

57 ts with grass pollen allergy with CRSwNP and nonallergic control subjects.

58 tal IgE, 133-4692 IU/mL; n = 28) and healthy nonallergic controls (n = 12) using peptide/MHCII tetram

59 Compared to nonallergic controls (n = 18), individuals with immediat

60 ically reactive) to milk, egg, or peanut and nonallergic controls for stimulation with endotoxin and

61 38 AR sufferers and eight nonallergic controls were exposed to grass pollen for 3

62 ith immediate allergic reactions compared to nonallergic controls, allergic patients produced functio

63 moderate, persistent asthma and 10 matched, nonallergic controls, and then incubated with concentrat

64 in serum were similar to levels measured in nonallergic controls, but HDM-specific levels of IgA2 in

65 cells from nickel-allergic patients, but not nonallergic controls, show significant IL-9 production i

66 L-5, and IL-13) content relative to those in nonallergic controls.

67 vivo in patients with PEG allergy but not in nonallergic controls.

68 accines bound Fcgamma receptors similarly to nonallergic controls.

69 er psychosocial outcomes compared with their nonallergic counterparts; however, few studies have pros

70 inflammatory responses in both allergic and nonallergic disease.

71 itis up to 16 years of age, particularly for nonallergic disease.

72 an important cytokine in the pathogenesis of nonallergic diseases, especially in diseases that includ

73 s obtained from allergic patients (n=11) and nonallergic donors (n=5).

74 ed higher proliferation to grass pollen than nonallergic donors (P = 0.002, and 0.010, respectively),

75 ression in blood DCs of patients and healthy nonallergic donors by qPCR.

76 OD1-primed dendritic cells from allergic and nonallergic donors were characterized in vitro on their

77 rmal CCL22 and IL-10 secretion compared with nonallergic donors.

78 in an indirect assay by using basophils from nonallergic donors.

79 ects demonstrated less clonality compared to nonallergic donors.

80 rstood, but likely include both allergic and nonallergic elements.

81 been limited by a poor understanding of how nonallergic environmental exposures, such as air polluti

82 e-to-severe remodeled asthma, (3) late-onset nonallergic eosinophilic asthma, and (4) late-onset nona

83 nflammation in response to both allergic and nonallergic exposures and suggest that airway inflammato

84 s might regulate asthma, particularly in its nonallergic forms, such as asthma associated with air po

85 nary stent implantation were compared with a nonallergic group (n=250) matched for demographics and a

86 osinophil degranulation in both allergic and nonallergic groups.

87 pheral blood and nasal biopsy specimens from nonallergic healthy control subjects (n = 3) and patient

88 ute anaphylaxis with several control groups (nonallergic, history of allergen-triggered anaphylaxis,

89 d, including those that rely on allergic and nonallergic humoral and antibody-dependent cellular resp

90 mmatory conditions, such as the psoriasis, a nonallergic hyperproliferative skin inflammatory disorde

91 trategies to prevent or inhibit allergic and nonallergic hypersensitivity.

92 Ag exposure through induction of a modified, nonallergic immune response.

93 DHRs may be allergic or nonallergic in nature, with drug allergies being immunol

94 hil levels, with a more pronounced effect in nonallergic individuals (65.9 +/- 25.3 vs 1.4 +/- 1.1 eo

95 cates that allergen-specific CD4+ T cells in nonallergic individuals are distinct from those in aller

96 Peanut-specific CD8(+) T cells in nonallergic individuals are not deleted, but have an exp

97 e addition of alpha-gal-specific IgG Ab from nonallergic individuals changed the IgE recognition of B

98 the pathological pathways are controlled in nonallergic individuals remains unclear.

99 (PBMC) culture from CM allergic patients and nonallergic individuals were assessed.

100 cytokine pattern to allergic donors, whereas nonallergic individuals were essentially nonreactive.

101 -positive cells in cultures from HLA-DR*0401 nonallergic individuals, even after expansion with IL-2.

102 her alpha-gal-specific IgG1 and IgG3 Ab than nonallergic individuals, whereas the latter showed signi

103 types of APC from birch pollen-allergic and nonallergic individuals.

104 mans, and differ in function in allergic and nonallergic individuals.

105 ation of BAT nonresponders into allergic and nonallergic individuals.

106 inct from natural alpha-gal IgG responses in nonallergic individuals.

107 ug of rMal d 1 induced no reactions in three nonallergic individuals.

108 ly higher frequency in allergic infants than nonallergic infants (P < .004); the high fecal count of

109 Levels of human lipocalins are elevated in nonallergic inflammation and cancer, associated with inn

110 rtantly, the repeated cycles of allergic and nonallergic inflammation that comprise chronic human air

111 de effects on lung development, allergic and nonallergic inflammation, and airway remodeling.

112 The (patho)physiological role of IgE in nonallergic inflammatory diseases is not well understood

113 mplicated as a mediator in both allergic and nonallergic inflammatory diseases, including allergic rh

114 tentially contributes to the pathogenesis of nonallergic (intrinsic) asthma and, accordingly, may und

115 dust mites (HDMs) (M+) and 15 nonsensitive, nonallergic (M-) participants completed 3-hour exposures

116 re associated with allergen-specific IgE and nonallergic mechanisms that may coexist in the same pati

117 y epithelium and smooth muscle compared with nonallergic mice, a finding which is replicated in sever

118 influx when infected with RSV compared with nonallergic mice, whereas viral clearance was comparable

119 es thus evokes an allergic state in normally nonallergic mice, which suggests the possibility of neur

120 , as well as airway hyperreactivity (AHR) in nonallergic mice.

121 CF was detected compared to fibroblasts from nonallergic mice.

122 was observed in allergic mice as well as in nonallergic mice.

123 l and macrophage influx and IFN responses in nonallergic mice.

124 nd n-6 PUFAs in breast milk of allergic- and nonallergic mothers and asthma, eczema and sensitization

125 .31-0.79), and more prevalent in children of nonallergic mothers receiving breast milk with higher le

126 gnificantly lower among children of the 8059 nonallergic mothers who consumed more P/TN in their peri

127 of 14 years in children of both allergic and nonallergic mothers.

128 cantly lower PKC levels than the children of nonallergic mothers.

129 tolerant (n = 36) and non-peanut-sensitized nonallergic (n = 25) children underwent skin prick test

130 79), sensitized (n = 40) and nonsensitized, nonallergic (n = 37) infants by multiplex assay.

131 asymptomatic allergic rhinitis (AR), and 11 nonallergic (N).

132 investigation of immune cell responses from nonallergic (NA) and peanut allergic (PA) participants c

133 PA (n = 56), PS (n = 42) and nonsensitized nonallergic (NA, n = 10) patients were studied.

134 ilic allergic; NEA and eight noneosinophilic nonallergic; NN) and nine healthy controls in high altit

135 IFN-alpha, P= .004; IFN-lambda1, P= .02) and nonallergic nonasthmatic children (IFN-alpha, P= .002; I

136 dritic cells when compared with that seen in nonallergic nonasthmatic children.

137 h a single early airway reaction (AA-S), and nonallergic nonasthmatic control subjects.

138 teen allergic asthmatic (AA) patients and 18 nonallergic nonasthmatic subjects (healthy volunteers [H

139 e blood of nonasthmatic patients with AR and nonallergic nonasthmatic subjects.

140 ts, 25 nonasthmatic patients with AR, and 19 nonallergic nonasthmatic subjects.

141 SPINK5, and TSLP in asthmatic, allergic, and nonallergic nonasthmatic white and black children partic

142 rgic eosinophilic asthma, and (4) late-onset nonallergic noneosinophilic asthma.

143 s allergic rhinitis, infectious rhinitis and nonallergic, noninfectious rhinitis.

144 frequent, but the effect of PPD exposure in nonallergic occupationally exposed subjects is unknown.

145 No major changes in ses-IgE were seen in nonallergic or sensitized children.

146 tantial subgroup of asthmatic patients have "nonallergic" or idiopathic asthma, which often takes a s

147 ith different asthma phenotypes (allergic vs nonallergic) or severities.

148 rgic parents and 43% (225 participants) with nonallergic parents.

149 Class 1 (25%): nonallergic participants without bronchial or ocular sym

150 13 and IL-1B genes was found in allergic and nonallergic participants, suggesting that in vivo, epige

151 re measured in tonsil tissue of allergic and nonallergic patients and in peripheral blood of allergic

152 oducibly distinguish cefazolin-allergic from nonallergic patients using finely tuned cefazolin-hapten

153 Overall, 97% of all trough levels of nonallergic patients were > 100 IU/L.

154 Sera from 19 allergic and nonallergic patients were included.

155 th allergic asthma, but surprisingly also in nonallergic patients with (severe) asthma.

156 y impulse oscillometry in female late-onset, nonallergic patients with asthma and control subjects be

157 nd, placebo-controlled study of allergic and nonallergic patients with nasal polyps and comorbid asth

158 pitope is prevalent among diverse cohorts of nonallergic peanut-consuming infants and peanut-allergic

159 st risk of asthma diagnosis, the more common nonallergic phenotypes (in 88.3% of participants) contri

160 Most importantly, nonallergic phenotypes accounted for more than two-third

161 symptoms were more frequently observed among nonallergic phenotypes as compared with allergic phenoty

162 n to modulate responses to both allergic and nonallergic provocation.

163 hypersensitivity includes allergic (AR) and nonallergic reactions (NARs) influenced by genetic predi

164 ntial to differentiate proven allergies from nonallergic reactions, ensure effective treatment, and a

165 unization of mice with PM induces a shift to nonallergic responses and increases the frequency of spl

166 besity was associated with increased odds of nonallergic rhinitis (adjusted odds ratio, 1.43; 95% CI,

167 cts with chronic fatigue syndrome (CFS) with nonallergic rhinitis (n = 14), subjects with active alle

168 ffect the risk of allergic rhinitis (AR) and nonallergic rhinitis (NAR) at 8 years of age.

169 nd development of allergic rhinitis (AR) and nonallergic rhinitis (NAR) between the ages of 8 and 16

170 , the differential diagnosis between LAR and nonallergic rhinitis (NAR) has become a challenge for th

171 Both allergic rhinitis (AR) and nonallergic rhinitis (NAR) patients can elicit nasal hyp

172 T) into the LAR, allergic rhinitis (AR), and nonallergic rhinitis (NAR) phenotypes.

173 ice parameter for allergic rhinitis (AR) and nonallergic rhinitis (NAR) provides updated guidance on

174 tis (AR), the degree of impairment in QoL in nonallergic rhinitis (NAR) remained unknown for a long t

175 Nonallergic rhinitis (NAR) was defined as clinically rel

176 The prevalence of nonallergic rhinitis (NAR) was significantly higher in e

177 perennial local allergic rhinitis (LAR), six nonallergic rhinitis (NAR), and six healthy control (HC)

178 llergic rhinitis (AR) with systemic atopy or nonallergic rhinitis (NAR).

179 (rhinitis with sensitization to allergens), nonallergic rhinitis (rhinitis without sensitization), a

180 aeroallergens and the secondary outcomes of nonallergic rhinitis and AR plus asthma.

181 ntrast, first-line therapy for patients with nonallergic rhinitis consists of an intranasal antihista

182 ars, whereas the proportion of children with nonallergic rhinitis decreased slightly over the same pe

183 Patients with nonallergic rhinitis have negative test results for spec

184 besity was associated with increased odds of nonallergic rhinitis in adults (adjusted odds ratio, 1.6

185 of patients previously given a diagnosis of nonallergic rhinitis or idiopathic rhinitis are now bein

186 rformed at 1-2-month interval in AR, LAR and nonallergic rhinitis patients, and in healthy controls.

187 Patients with nonallergic rhinitis present primarily with nasal conges

188 Nonallergic rhinitis was defined as a physician's diagno

189 Nonallergic rhinitis was least common (11.3%) and least

190 ng 4- and 8-year-olds, allergic rhinitis and nonallergic rhinitis were associated with asthma, eczema

191 s 12 years of age and older with allergic or nonallergic rhinitis were enrolled in a noninterventiona

192 dermatitis), non-T2 diseases (T2-low asthma, nonallergic rhinitis) and assessment of T2 biomarkers (b

193 they were 8 years old; of the children with nonallergic rhinitis, 73% underwent remission during thi

194 evalence and morbidity of allergic rhinitis, nonallergic rhinitis, and chronic rhinosinusitis.

195 treat disorders such as asthma, allergic and nonallergic rhinitis, and food allergy.

196 obesity is associated with increased odds of nonallergic rhinitis, particularly in male subjects.

197 of breastfeeding were stronger predictors of nonallergic rhinitis, whereas current wheeze and eczema

198 sk factors and severity between allergic and nonallergic rhinitis.

199 an 47% of patients previously diagnosed with nonallergic rhinitis.

200 initis, and differences between allergic and nonallergic rhinitis.

201 hinitis undergo remission than do those with nonallergic rhinitis.

202 ved for atopic dermatitis, T2-low asthma, or nonallergic rhinitis.

203 ins unclear, and the requirement for BATF in nonallergic settings of type-2 immunity has not been exp

204 er of mucociliary clearance, in allergic and nonallergic sheep.

205 nts with both Th2-type allergic and Th1-type nonallergic sinusitis.

206 ceptor can be activated by both allergic and nonallergic stimuli, leading to several pro-inflammatory

207 ithout birch pollen allergy (group 3), and 5 nonallergic subjects (group 4) by performing skin prick

208 Allergic subjects (n = 6) and nonallergic subjects (n = 4) were treated in season for

209 = 7) and mild (n = 10) allergic patients and nonallergic subjects (n = 9) to perform platelet lipidom

210 vus, which tended to have a low frequency in nonallergic subjects (P = .0004).

211 -induced histamine release from basophils in nonallergic subjects and allergen-induced histamine libe

212 RANTES intradermally into both allergic and nonallergic subjects and obtained biopsies 30 min, 6 h,

213 sent at low frequencies in both allergic and nonallergic subjects and reflect classical features of t

214 e grass allergen-specific T cells in DR*0401 nonallergic subjects are present at very low levels (e.g

215 nvolved the production of CCL17 and CCL22 in nonallergic subjects but only CCL17 in allergic patients

216 d stronger complement activation compared to nonallergic subjects following ex vivo vaccine exposure.

217 nonfall birth between (i) food allergic and nonallergic subjects in NHANES, adjusted for ethnicity,

218 DC responses between human food-allergic and nonallergic subjects is necessary to gain a better insig

219 The TCLs of nonallergic subjects mostly secreted IFN-gamma and IL-10

220 f the subjects with alder pollen allergy and nonallergic subjects tested.

221 ch allergy and tolerance to peanut; Group 4, nonallergic subjects that tolerate both peanut and peach

222 gic patients or exposure of neutrophils from nonallergic subjects to allergic donor serum in vitro im

223 from sera of 30 birch pollen-allergic and 11 nonallergic subjects to Bet v 1, 13 chimeric proteins, a

224 mory CD4(+) T-cell responses of allergic and nonallergic subjects to Can f 4.

225 response to a profilin challenge test and 6 nonallergic subjects were recruited.

226 cells (PBMCs) from peanut-allergic (PA) and nonallergic subjects were stimulated (14-16 h) with pean

227 10 age-matched mild-asthmatic and 10 healthy nonallergic subjects were used for comparison.

228 nd were significantly different from healthy nonallergic subjects who had also undergone NAC.

229 placebo) and specificity (very low score in nonallergic subjects) in the GA(2)LEN chamber.

230 ith PA, 77 PS patients, and 43 nonsensitized nonallergic subjects) were studied.

231 in 12 subjects with alder pollen allergy, 6 nonallergic subjects, and 9 allergy vaccine-treated subj

232 B cells from allergic, but not nonallergic subjects, are able to produce IgG4 after cog

233 Likewise, BAT recognized 12 of 14 nonallergic subjects, HR 10, and passive HR 13.

234 for walnut-reactive T cells in allergic and nonallergic subjects, particularly the relationship of p

235 ese diseases and are also present in healthy nonallergic subjects, we performed global transcriptiona

236 old higher frequency from allergic than from nonallergic subjects.

237 to Can f 4 are observed in allergic but not nonallergic subjects.

238 inate in allergic subjects but are absent in nonallergic subjects.

239 ave diagnosed asthma or asthma symptoms than nonallergic subjects.

240 o-way crossover studies and an open study in nonallergic subjects.

241 ed more rapidly in allergic subjects than in nonallergic subjects.

242 cts and revealed a T(H)1/T(H)17 signature in nonallergic subjects.

243 f IgE and IgG from birch pollen-allergic and nonallergic subjects.

244 ith the IgE repertoires in both allergic and nonallergic subjects.

245 were performed on 11 peanut-allergic and 14 nonallergic subjects.

246 specific CD4(+) T cells between allergic and nonallergic subjects.

247 k histories include patients having isolated nonallergic symptoms, such as gastrointestinal symptoms,

248 to untreated HCEs or with HCEs treated with nonallergic tears and untreated HCEs (P < 0.05).

249 sed risk from regular smoking was greater in nonallergic than in allergic children.

250 ed histamine release after both allergic and nonallergic triggers.

251 CR2, and CXCR4 expression, as well as (5) in nonallergic versus allergic subjects.

252 ernal cohort of 71 patients (29 allergic, 42 nonallergic), with an area under the curve of 0.908 (sen

253 ice displayed the same 50% graft survival as nonallergic WT mice, that was significantly less than th