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2 his article that KIR3DL2 and KIR2DS4 and the nonclassical Ag HLA-F, expressed as a free form devoid o
5 ted with alternative activation, whereas the nonclassical and classical populations demonstrated an a
6 lammatory phenotype defined by (1) increased nonclassical and intermediate monocytes, (2) a proinflam
7 e mechanism of crystallization, classical or nonclassical; and whether quinoline antimalarials inhibi
10 ied enzymes differed among salt-wasting- and nonclassical-associated variants, but these differences
11 y identified in the components of the HPV is nonclassical because the mean structure of the epitope c
14 onfirm that aztreonam-like beta-lactams plus nonclassical beta-lactamase inhibitors, particularly avi
15 ique population of kidney T cells, depend on nonclassical beta2m molecules for homeostasis and use MH
17 approach to peptide conjugation based on the nonclassical bioisosteric replacement of the guanidine g
18 emokine receptor 2-dependent manner, and the nonclassical blood resident monocyte subset that patrols
20 binding fragments, including a selection of nonclassical CA II binding chemotypes, were identified.
23 es indicate that the reaction proceeds via a nonclassical carbocation followed by anti-1,2-migration.
26 luded proving the occurrence of benzynes and nonclassical carbocations as reaction intermediates, and
29 monocytes with classical CD14(++)CD16(-) and nonclassical CD14(+)CD16(++) monocytes revealed that the
30 ease in the classical (CD14(++) CD16(-)) and nonclassical (CD14(+) CD16(+)) subsets at 12 days postin
32 in humans and Ly6C(+)Treml4(+) in mice), and nonclassical (CD14(-)CD16(+) in humans and Ly6C(lo) in m
35 6(+) (both intermediate [CD14(+)CD16(+)] and nonclassical [CD14(dim)CD16(+)]) monocytes was increased
36 aracterized by reduced levels of circulating nonclassical CD16(+) monocytes with a poor activation pr
40 ho-hydrogen to participate in a stabilizing, nonclassical CH...O hydrogen bond with a ring oxygen of
43 Thus, protoadamantyl zwitterion has a less nonclassical character than the corresponding cation, so
44 uctural features that are similar to certain nonclassical class I genes in other vertebrates, and, un
48 s one of our examples, we apply STS to check nonclassical correlations among sites in a photosyntheti
50 hese STS measures enable a new way to assess nonclassical correlations in an open quantum network, su
52 might be reconciled by invoking a three-step nonclassical crystal growth mechanism comprising (i) doc
53 s via both conventional Ostwald ripening and nonclassical crystallization by particle attachment.
55 further source of inspiration how to exploit nonclassical crystallization routes for syntheses of str
56 systems, microfluidic systems (classical and nonclassical), custom-built polymerase chain reaction de
58 were identified in a 5-year-old patient with nonclassical DBA and in a 17-year-old patient with myelo
65 se had higher event rate than did those with nonclassical disease (hazard ratio for men, 5.63, 95% co
67 e had a history of more events than men with nonclassical disease or women with either phenotype; wom
70 The present review offers an overview of nonclassical (e.g., with no pre- or in situ activation o
71 E2 in the late stages of pregnancy through a nonclassical E2/ERalpha transrepressive pathway, directl
73 ng a simple yet rigorous platform to include nonclassical effects in plasmon-enabled nanophotonic phe
74 r dynamics techniques to shed light on these nonclassical effects, which are often difficult to inves
77 tric triplet (omega(flap) = 0 deg) stem from nonclassical electron delocalization in the former and t
78 ic process of recombination and propose that nonclassical excision circles are liberated during the f
79 tom and the H6 of the base, reminiscent of a nonclassical F...H hydrogen bond, could be observed.
80 osylsphingosine concentrations than men with nonclassical Fabry disease or women with either phenotyp
84 ssical (physicochemical and topological) and nonclassical (fingerprints) molecular descriptors of 138
85 nd that more than 50% of patients could have nonclassical food allergy, with immediate disruption of
86 iants associated with either salt-wasting or nonclassical forms of CAH were expressed, purified, and
89 equirement of the class Ib molecule, Xenopus nonclassical gene 10, in its differentiation and functio
92 ore, the GRP88 nuclear localization suggests nonclassical GPCR modes of action of the protein that co
93 at SSZ-13 grows by two concerted mechanisms: nonclassical growth involving the attachment of amorphou
102 at miR-152 overexpression down-regulates the nonclassical human leukocyte antigen (HLA) class I molec
103 ocatalysts toward the reaction revealed that nonclassical hydrogen bonding was involved in the stabil
105 We report an experimental demonstration of a nonclassical imaging mechanism with super-resolving powe
106 mmunoprecipitation analyses, revealed that a nonclassical importin beta family member, IPO3, was the
107 was 0.7% (8/1078) and was 16.7% (9/54) for "nonclassical" indications (peritonitis, carcinomatosis,
109 articles are therefore expected to exhibit a nonclassical inhomogeneous spectral broadening due to si
110 e the output distribution resulting from the nonclassical interference of photons in an integrated ph
111 previous complexities and the first on-chip nonclassical interference with more than two photonic in
113 precise FcgammaR repertoire on classical and nonclassical intermediate monocytes--M1 and M2c macropha
114 monocytes cocultures (IL-6(hi)) was added to nonclassical/intermediate monocyte cocultures (TNF(hi)),
115 vels of TNF were detected in cocultures with nonclassical/intermediate monocytes, the blockade of whi
117 characterization, and catalytic activity of nonclassical iron(II) polyhydride complexes containing t
118 vel spectroscopic capabilities provided by a nonclassical light excitation, this is of critical impor
120 ers in future photonic applications, such as nonclassical light sources for quantum communication or
121 erate and characterize frequency-multiplexed nonclassical light sources for quantum info-communicatio
122 Semiconductors can also be used to generate nonclassical light; in fact, CMOS-compatible silicon chi
124 have uncovered an immunosuppressive role for nonclassical Ly6Clo monocytes that mediates resistance t
125 rized macrophage depletion and inhibition of nonclassical macrophage migration, in addition to direct
127 , in addition to direct interactions between nonclassical macrophages and fibroblasts in angiotensin
129 ntrolled expansion that was dependent on the nonclassical major histocompatibility complex (MHC) prot
131 in human; murine H2-O) is a highly conserved nonclassical major histocompatibility complex class II (
134 Ab-mediated immunity, while suggesting a new nonclassical mechanism of Ab function, which may apply t
135 ters in the bulk liquid is associated with a nonclassical mechanism of crystal growth and can trigger
141 ew, we discuss the evidence supporting these nonclassical megakaryocytic differentiation pathways and
144 repertoire presented by classical as well as nonclassical MHC class I (MHC I) molecules is altered in
145 of jawed vertebrates, we identified a third nonclassical MHC class I lineage (UDA), which is present
147 ain and recognize lipid Ags presented by the nonclassical MHC class I molecule CD1d are probably the
148 -forming NKG2D, NKG2 receptors recognize the nonclassical MHC class I molecule HLA-E, and they can be
152 eign and self-lipids in association with the nonclassical MHC class I-like molecules, CD1 proteins.
155 a highly conserved, ubiquitously expressed, nonclassical MHC class Ib molecule with limited polymorp
156 ariant Valpha6 [iValpha6]) restricted by the nonclassical MHC class Ib molecule XNC10 in the amphibia
159 d immunogenicity of peptides associated with nonclassical MHC I was increased in the absence of ERAAP
164 lationships, including those associated with nonclassical MHC-I, have yet to be clearly defined.
165 lity complex E (MHC-E) is a highly conserved nonclassical MHC-Ib molecule that tightly binds peptides
166 cells is controlled by the interplay of the nonclassical MHCII molecules, HLA-DM (DM) and HLA-DO (DO
168 its replacement with an organic results in a nonclassical mode of growth that obscures 2D layers and
169 vity in the brain, much of which can involve nonclassical modes of neuronal firing and integration.
171 hat myeloid cells, specifically cells of the nonclassical monocyte lineage, play a direct role in the
172 ed using highly purified human classical and nonclassical monocyte subsets from a clinical cohort, al
173 )/CD16(+) intermediate and CD14(low)/CD16(+) nonclassical monocyte subsets in peripheral blood mononu
176 , mice that have markedly reduced numbers of nonclassical monocytes (CX3CR1(-/-)) exhibited a signifi
178 indicate that inflammatory transitional and nonclassical monocytes and CD1c+ conventional dendritic
179 an) can define slan-positive CD14(+)CD16(++) nonclassical monocytes and slan-negative CD14(++)CD16(+)
180 that, in murine hypoxia-induced PH, Ly6C(lo) nonclassical monocytes are recruited to small pulmonary
181 tribution of these monocyte subsets with the nonclassical monocytes being expanded (almost 2-fold) in
182 d hierarchical clustering, the slan-positive nonclassical monocytes cluster with monocytes and are cl
183 ly higher baseline peripheral frequencies of nonclassical monocytes compared with nonresponder patien
184 To determine if the sensing of hypoxia by nonclassical monocytes contributes to the development of
186 deposition were generated for classical and nonclassical monocytes defining enhanceosomes of the 2 m
187 CCR5, was higher, and a higher proportion of nonclassical monocytes expressed CCR1, CXCR3, and CX3CR1
188 riming them for anaerobic energy production, nonclassical monocytes expressed higher levels of oxidat
191 ons, similar to classical, intermediate, and nonclassical monocytes in humans, based upon CD14 and CD
192 findings show that, in response to hypoxia, nonclassical monocytes in the lung sense hypoxia, infilt
193 e adhesion of classical monocytes but not of nonclassical monocytes in the mouse cremaster muscle and
195 Subsequent labeling of intermediate and nonclassical monocytes is consistent with a model of seq
196 reen fluorescent protein) mice, we show that nonclassical monocytes patrol inside healthy carotid art
198 gage ex vivo FcgammaRIIIA (CD16)-expressing, nonclassical monocytes resulting in ADCC-mediated lysis
199 d become infected and the number of infected nonclassical monocytes that transmit virus to CD4(+) and
200 intermediate monocytes are more likely than nonclassical monocytes to migrate to the lesion site.
202 ial patrolling is a prominent new feature of nonclassical monocytes with unique molecular and kinetic
203 nocyte subsets (classical, intermediate, and nonclassical monocytes) to the total viral burden in 22
204 F(V600E) was tracked to classical monocytes, nonclassical monocytes, and CD1c(+) myeloid dendritic ce
207 sical and intermediate monocytes, but not in nonclassical monocytes, which nonetheless display a very
214 allization within the membrane media follows nonclassical multistep crystallization governed by the h
217 cales via both classical spike-dependent and nonclassical neuropeptide-dependent mechanisms.SIGNIFICA
219 sistance can occur through activation of the nonclassical NF-kappaB pathway and acquired resistance m
220 B-cell receptor and JAK/STAT signaling, the nonclassical NF-kappaB pathway, cell-cycle regulation, a
224 The larger Ga and In ions stabilize rare, nonclassical Ni-H2 adducts that catalyze olefin hydrogen
225 he interaction of TNPO1 and TNPO3 with these nonclassical NLSs may regulate the formation of membrane
226 NPO1 and Transportin-3 (TNPO3) recognize two nonclassical NLSs within the cold-inducible RNA-binding
228 In the complex, eVP24 recognizes a unique nonclassical nuclear localization signal (NLS) binding s
229 dict that low coordination numbers result in nonclassical nucleation behavior, which we find to be es
230 These new pathways include the so-called nonclassical nucleation mechanism via the assembly of th
233 g of classic, proinflammatory monocytes into nonclassical or alternative monocytes to facilitate prop
234 3213128 (compound 28a), a novel, selective, nonclassical, orally bioavailable antifolate with potent
235 rgos, and we raise the possibility that this nonclassical pathway is shared by most AAV variants, reg
236 g prospects for exerting control over such a nonclassical pathway to crystallization to design minera
237 1B10 is secreted through a lysosome-mediated nonclassical pathway, leading to an increase in the seru
238 silica molecules as primary growth units and nonclassical pathways based on the aggregation of metast
239 lite crystallization predominantly occurs by nonclassical pathways involving the attachment of comple
240 s are either known or postulated to grow via nonclassical pathways involving the initial self-assembl
243 -transmission electron microscopy, revealing nonclassical pathways via dissolution-recrystallization
246 tumorigenesis and cancer metastasis, but how nonclassical "patrolling" monocytes (PMo) interact with
248 or proinflammatory (CCR2(hi)CX3CR1(low)) and nonclassical, patrolling, or alternative (CCR2(low)CX3CR
249 In this article, we demonstrate that the nonclassical peroxisome proliferator 4-phenyl butyric ac
252 mechanistic information, aimed at developing nonclassical platinum complexes that operate via mechani
253 We then describe approaches that explore nonclassical platinum(II) complexes with trans geometry
254 s and the lectin-like receptor CD94-NKG2A by nonclassical pMHC-I complexes, in each case leading to n
256 nambiguously to specifically bind zinc via a nonclassical, potentially catalytic zinc-binding motif.
263 with transduction efficiency and relies on a nonclassical retrograde transport pathway that is indepe
269 ss potential functions of both classical and nonclassical sHLA-I, using soluble recombinant HLA-I/pep
270 r DFT calculations reveal the formation of a nonclassical sigma-hole region with one or even two maxi
271 At the limit, the tuning transforms the nonclassical sigma-hole regions into coordination sites,
276 a rare phenomenon otherwise known only from nonclassical states of light like the squeezed vacuum.
280 LR) agonists in classical, intermediate, and nonclassical subsets of monocytes by assessing intracell
281 subdivided into classical, intermediate, and nonclassical subsets, but there is no unequivocal strate
282 erapy agents and humanized mAbs present with nonclassical symptoms of anaphylaxis, and patients may p
284 RNA (siRNA) knockdown studies suggested that nonclassical targets of sorafenib are important for the
286 kingly, induced marked production of diverse nonclassical TH2 inflammatory mediators, including IL-22
287 allergy, regulatory immune cell subsets and nonclassical Th2-biased inflammatory mediators in the tu
288 dependently of IFN-gamma and IL-17; however, nonclassical Th22 cells have been recently identified an
290 most efficiently triggered the expansion of nonclassical Th22 subsets from memory T cells and classi
291 Little is known about how classical and nonclassical Th22 subsets in human diseases are regulate
292 three subsets (classical, intermediate, and nonclassical) that circulate in dynamic equilibrium.
293 Our findings are independent of the specific nonclassical theory used, thus providing important insig
294 d retinoid X receptor (RXR) by classical and nonclassical THs as another molecular activity of THs.
295 dulation are reviewed, with special focus on nonclassical TLR4 ligands with a chemical structure diff
297 We observe classical one-step pathways and nonclassical two-step pathways that proceed via a solid-
298 med) [intermediate], and CD14(neg)/CD16(hi) [nonclassical]) were examined at homeostasis and after ac
299 ation of cells (classical, intermediate, and nonclassical) with distinct functions, however, the recr
300 ial step of the synthesis is cyclization via nonclassical Wittig olefination of resin-bound esters.