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1 ion rate controlled mechanism of allosteric, noncompetitive inhibition.
2 tosterone binding to AR-T877A likely through noncompetitive inhibition.
3 nable to distinguish between competitive and noncompetitive inhibition.
4 s not affected by NorA expression, exhibited noncompetitive inhibition.
5 by the lack of a structural understanding of noncompetitive inhibition.
6 ts metabolites demonstrate mixed competitive/noncompetitive inhibition.
7 e of the inhibitor and which may explain the noncompetitive inhibition.
9 Acetylated (Lys14Ac) H3 peptide displayed noncompetitive inhibition against both H3 peptide and Ac
10 te substrates ATP and CEA, respectively, and noncompetitive inhibition against their noncognate subst
11 such compound, ALS 1-0635, indicated linear, noncompetitive inhibition, and Dixon plot analysis from
18 arsenate has been examined, and reversible, noncompetitive inhibition by theophylline has been studi
19 proteins by differentiating competitive and noncompetitive inhibition demonstrates its ability as a
21 (ACh), PhTX-343 caused activation-dependent, noncompetitive inhibition (IC50 = 17 microM at -100 mV)
22 hibition in regard to external [K(+)] versus noncompetitive inhibition in respect to external [Cl(-)]
24 m), whereas a Ubc5BC85A product analog shows noncompetitive inhibition (Ki = 2.2 +/- 0.5 mum), consis
26 , the hydroxamic acid, SC81956, demonstrated noncompetitive inhibition kinetics with a Ki of 23 nM.
27 time-dependent inhibitors of PC2, exhibiting noncompetitive inhibition kinetics; the most potent inhi
28 nhibit the C-terminal sEH activity through a noncompetitive inhibition mechanism involving a new bind
30 ibited hTP in the submicromolar range with a noncompetitive inhibition mode with both thymidine and i
31 y competition with substrate, and the linear noncompetitive inhibition observed was consistent with i
32 Our results represent a molecular view into noncompetitive inhibition of a sodium-coupled transporte
33 elective and, with respect to the substrate, noncompetitive inhibition of Abeta(1-42) production was
34 .77 microM at-100 mV), activation-dependent, noncompetitive inhibition of ACh-induced whole-cell curr
35 terol cyclase (OSLC) inhibitor showed potent noncompetitive inhibition of bacterial squalene:hopene c
38 tly inhibit monocyte recruitment through the noncompetitive inhibition of CCL2-induced ERK1/2 activat
42 peptidyl substrate cleavage but as classical noncompetitive inhibition of factor X activation by acti
45 ,3', 5-L-triiodothyronine (L-T3) indicated a noncompetitive inhibition of muscimol-stimulated (36)Cl(
47 tory compound, termed JF5, also demonstrated noncompetitive inhibition of the alpha(2A)-adrenergic re
48 strychnine-insensitive glycine binding site (noncompetitive inhibition of the binding of [3H]TCP, pA2
50 resulting in binding to activated fVIII and noncompetitive inhibition of the intrinsic fXase complex
52 d that copper (I) and (II) cations displayed noncompetitive inhibition of the LC (Ki approximately 1
54 show that the synthetic Mag-1 peptides cause noncompetitive inhibition of the receptor channel activi
56 is the most potent inhibitor, effecting pure noncompetitive inhibition of the wild type human AMPD3 r
57 osolic GR without affecting K(m), suggesting noncompetitive inhibition of this thiol-dependent enzyme
60 at high neomycin concentrations, indicating noncompetitive inhibition rather than direct competitive
61 onal UV-vis spectroscopy, and competitive vs noncompetitive inhibition reactions could be delineated
62 Consistent with the observed time-dependent noncompetitive inhibition, the cocrystal X-ray structure
63 l molecule analinopyrimidine, exhibited pure noncompetitive inhibition versus ATF2 and competitive in
64 e hydrolyzed peptide product, Pd1, exhibited noncompetitive inhibition versus both ATP and S3 substra
65 hibits competitive inhibition versus ATP and noncompetitive inhibition versus cysteine, with an inhib
67 t displays allosteric site binding behavior (noncompetitive inhibition vs l-Ser substrate; competitiv
70 both classes of compounds display primarily noncompetitive inhibition with respect to either ATP or
71 ibition pattern with respect to pyruvate and noncompetitive inhibition with respect to GAP/d-glyceral
72 respect to erythrose-4-phosphate and partial noncompetitive inhibition with respect to phosphoenolpyr
73 y of triclosan for the enzyme and results in noncompetitive inhibition, with K(i) and K(i)' values of
74 ncentrations and acted predominantly through noncompetitive inhibition without impacting membrane exp