ライフサイエンスコーパス: nonesterified fatty acid

1 line, triglycerides, cholesteryl esters, and nonesterified fatty acids).

2 essing harmful intracellular accumulation of nonesterified fatty acid.

3 iators, lysophosphatidylcholine and oxidized nonesterified fatty acid.

4 orary storage site for energy in the form of nonesterified fatty acids.

5 ercise elicit an immediate increase in serum nonesterified fatty acids.

6 nge in the pattern of total, esterified, and nonesterified fatty acids.

7 rations, and were negatively associated with nonesterified fatty acids.

8 ators, lyso-phosphatidylcholine and oxidized nonesterified fatty acids.

9 is likely due to decreased beta-oxidation of nonesterified fatty acids.

10 was accounted for by MAP, triglycerides, and nonesterified fatty acids.

11 creases cholesterol synthesis and release of nonesterified fatty acids.

12 erol (12 +/- 3 to 258 +/- 47 micromol/l) and nonesterified fatty acid (194 +/- 10 to 540 +/- 80 micro

13 tion into triglyceride-rich lipoproteins and nonesterified fatty acid, AEE, and muscle markers were s

14 racteristic decrease from baseline in plasma nonesterified fatty acids after a mixed meal was inhibit

15 The d31-palmitate appearance in nonesterified fatty acid and very-low-density lipoprotei

16 had a lower concentration of fasting plasma nonesterified fatty acids and less hepatic steatosis.

17 Nonesterified fatty acids and lipid peroxidation were in

18 atty acyl chains from phospholipids to yield nonesterified fatty acids and lysophospholipids.

19 ease plasma concentrations of both TGRLs and nonesterified fatty acids and meal 2 to increase TGRLs o

20 In contrast, the liver pool sizes of nonesterified fatty acids and triglycerides were not alt

21 r epididymal fat pads, lower blood levels of nonesterified fatty acids and triglycerides, and higher

22 Lipolysis (glycerol, nonesterified fatty acids) and endogenous glucose produc

23 ous glucose production, lipolysis (glycerol, nonesterified fatty acid), and glycogenolysis (lactate)

24 i on exercise capacity, oxygen uptake, serum nonesterified fatty acid, and glucose were measured duri

25 ty lipoproteins, cholesterol, triglycerides, nonesterified fatty acids, and leptin, whereas adiponect

26 ced physical activity; increased circulating nonesterified fatty acids; and increased IMCLs, diacylgl

27 Nonesterified fatty acids are key intermediates in cellu

28 plasma glucose, branched chain amino acids, nonesterified fatty acids, beta-hydroxybutyrate, and uri

29 ese results also suggest that esterified and nonesterified fatty acids can bind to and regulate prote

30 Blood nonesterified fatty acid concentration was not affected

31 The nonesterified fatty acid concentration was significantly

32 ion, it increased lipid oxidation and plasma nonesterified fatty acid concentrations compared with HF

33 Nonesterified fatty acid concentrations were lower up to

34 serum insulin, glucose, triacylglycerol, and nonesterified fatty acid concentrations were measured, a

35 ts in increased serum levels of glycerol and nonesterified fatty acids, consistent with increased lip

36 to a meal produced TGRL that was enriched in nonesterified fatty acids, decreased IRF-1 expression, i

37 zed de novo in the liver from carbohydrates, nonesterified fatty acids derived from adipose tissue, n

38 ied fatty acids derived from adipose tissue, nonesterified fatty acids derived from the spillover of

39 ucagon-like peptide 1, insulin, glucose, and nonesterified fatty acids determined for 4 h.

40 Metabolic profiling of plasma nonesterified fatty acids discovered that palmitic acid

41 mass spectrometry was used to analyze free (nonesterified) fatty acid (FFA) and triacylglycerol flux

42 Plasma concentrations of triglycerides, nonesterified fatty acids, glucose, and insulin were mon

43 ed at 10-min intervals; blood triglycerides, nonesterified fatty acids, glucose, lactate, inflammator

44 Pathologically increased nonesterified fatty acids have widely been viewed as a k

45 beta-cell membrane phospholipids to release nonesterified fatty acids, including AA, and inhibiting

46 ome in db mice contributed high-glucose- and nonesterified fatty acid-induced osteoblast apoptosis th

47 the percentage of small dense LDL; glucose; nonesterified fatty acids; insulin; and the homeostasis

48 Adipose release of nonesterified fatty acids into plasma decreased by 53% a

49 eficient mice cleared blood triglyceride and nonesterified fatty acid less efficiently than wild-type

50 n of glucagon secretion, reduction in plasma nonesterified fatty acid level, decrease in the load of

51 ratio (P = 0.013), and, surprisingly, higher nonesterified fatty acid levels (P = 0.01).

52 ion decreases serum triacylglycerol (TG) and nonesterified fatty acid levels and improves insulin sen

53 rization associated with reduced circulating nonesterified fatty acid levels and normal glucose homeo

54 Fasting increased plasma nonesterified fatty acid levels in both lean and obese r

55 olysis but did not result in increased serum nonesterified fatty acid levels or ectopic TAG storage.

56 nd beta cell volume without affecting plasma nonesterified fatty acid levels, strongly suggesting tha

57 ks, without significant alteration of plasma nonesterified fatty acid levels.

58 Nonesterified fatty acids may influence mitochondrial fu

59 andial responses in plasma concentrations of nonesterified fatty acid (meal x time, P = 0.00014), tri

60 ution exerts a major influence on endogenous nonesterified fatty acid metabolism, which may in turn m

61 ctives were to determine the impact of KE on nonesterified fatty acid (NEFA) concentration and glucor

62 opic hormone (ACTH), cortisol, glucagon, and nonesterified fatty acid (NEFA) concentrations were not

63 ndrial function independent of reductions in nonesterified fatty acid (NEFA) concentrations.

64 VLDL particle and TG transport rates, plasma nonesterified fatty acid (NEFA) flux, and sources of fat

65 2)H(2)]palmitic acid to investigate systemic nonesterified fatty acid (NEFA) incorporation into VLDL

66 f various hormones and an increase in plasma nonesterified fatty acid (NEFA) levels and is mediated t

67 arin (0.5 U x kg(-1) x min(-1)) to clamp the nonesterified fatty acid (NEFA) levels during hyperinsul

68 Elevation of plasma nonesterified fatty acid (NEFA) levels has been shown in

69 widely regarded as monitors of intracellular nonesterified fatty acid (NEFA) levels.

70 Nonesterified fatty acid (NEFA) release was suppressed a

71 rd quantitative methods for determination of nonesterified fatty acid (NEFA) species are still missin

72 Determinants of insulin sensitivity based on nonesterified fatty acid (NEFA) suppression after oral g

73 ied BAT oxidative metabolism and glucose and nonesterified fatty acid (NEFA) turnover in 6 healthy me

74 ive metabolism and perfusion and glucose and nonesterified fatty acid (NEFA) turnover were determined

75 Plasma nonesterified fatty acids (NEFA) at elevated concentrati

76 Although nonesterified fatty acids (NEFA) have been positively as

77 Nonesterified fatty acids (NEFA) in urine are bound to a

78 gy for simultaneous quantitative analysis of nonesterified fatty acids (NEFA) species in biofluids is

79 ipose tissue lipolysis produces glycerol and nonesterified fatty acids (NEFA) that serve as energy so

80 ntrol subjects, but the rates of delivery of nonesterified fatty acids (NEFA) were downregulated, res

81 To evaluate the association of nonesterified fatty acids (NEFA) with dysglycemia in old

82 in resistance despite increasing circulating nonesterified fatty acids (NEFA), the main substrate for

83 mechanism involves leakage of albumin-bound nonesterified fatty acids (NEFAs) across the damaged glo

84 Impaired suppression of plasma nonesterified fatty acids (NEFAs) after glucose ingestio

85 We studied the effects of nonesterified fatty acids (NEFAs) and adipokines on acin

86 hus examined whether lipolytic generation of nonesterified fatty acids (NEFAs) from circulating trigl

87 Experimental elevation of nonesterified fatty acids (NEFAs) impairs endothelial fu

88 HDL, and LDL cholesterol; triglycerides; and nonesterified fatty acids (NEFAs) in a total of 139 OT1D

89 tissue increases lipolysis and the entry of nonesterified fatty acids (NEFAs) in the liver, whereas

90 issue there was significant uptake of plasma nonesterified fatty acids (NEFAs) in the postprandial bu

91 t growth factor 21 (FGF21), adiponectin, and nonesterified fatty acids (NEFAs) may be involved in ami

92 in conscious dogs to determine the effect of nonesterified fatty acids (NEFAs) on net hepatic glucose

93 We compared FAEEs levels with their nonesterified fatty acids (NEFAs) precursors during alco

94 Preliminary data suggest that plasma nonesterified fatty acids (NEFAs) raise plasma ANGPTL4 c

95 Autonomic symptom scores, lipid oxidation, nonesterified fatty acids (NEFAs), and glycerol response

96 isotopes for 4 days to label and track serum nonesterified fatty acids (NEFAs), dietary fatty acids,

97 High plasma concentrations of nonesterified fatty acids (NEFAs), transported bound to

98 rgans to circulating triglycerides (TGs) and nonesterified fatty acids (NEFAs), ultimately leading to

99 ed adipose triglyceride and generated excess nonesterified fatty acids (NEFAs), which caused organ fa

100 ic than hGV but releases a lower quantity of nonesterified fatty acids (NEFAs).

101 (VLDL)-triacylglycerols and plasma free FA [nonesterified fatty acids (NEFAs)] were analyzed by usin

102 Adipo-IR (fasting nonesterified fatty acids [NEFAs] x fasting insulin) was

103 r (P < 0.05), whereas glucose (P < 0.05) and nonesterified fatty acids (P < 0.0001) were higher.

104 occurred with elevated glucose, insulin, and nonesterified fatty acids peak after lunch.

105 fasting plasma insulin (r = 0.60, P < 0.05), nonesterified fatty acid (r = 0.63, P < 0.02), and gluco

106 y deplete [Ca(2+)](m) and thus contribute to nonesterified fatty acid-responsive mitochondrial dysfun

107 ction similarly in all groups and suppressed nonesterified fatty acids similarly between control subj

108 of glucose, lactate, and ketones and higher nonesterified fatty acids than wild type (WT) littermate

109 es results in the liberation of glycerol and nonesterified fatty acids that are released into the vas

110 n the dose-response curve for suppression of nonesterified fatty acids versus insulin levels in the N

111 This fall in nonesterified fatty acid was accompanied by a fall in th

112 Neither lipolysis nor flux of plasma nonesterified fatty acids were altered compared with bas

113 pid, triacylglycerol, cholesteryl ester, and nonesterified fatty acid) were extracted from fasting ba

114 fied non-HDL-cholesterol, triglycerides, and nonesterified fatty acids, with a minimum effective dose