ライフサイエンスコーパス: nonfluorescent

1 er reduced to hydroresorufin (uncoloured and nonfluorescent).

2 self-pollination, the ddm1/ddm1 lines became nonfluorescent.

3 rescent proteins and thus render macrophages nonfluorescent.

4 idase to selectively render unesterified DHE nonfluorescent.

5 ith an aldehyde group to render the molecule nonfluorescent.

6 luorescence assay, based on the oxidation of nonfluorescent 10-acetyl-3,7-dihydroxyphenoxazine (Ample

7 rs to form upon oxidative cyclization of the nonfluorescent 2:1 lysine-HNE Michael adduct-Schiff base

8 , 151, 160 167, 188, and 210 of cTnI and the nonfluorescent acceptor 4-(dimethylamino)phenylazophenyl

9 Using a nonfluorescent acceptor eliminates the necessity to spec

10 les containing a C5-DMB-lipid are mixed with nonfluorescent acceptor vesicles.

11 h the fluorescent donor 1,5-IAEDANS, and the nonfluorescent acceptor, DAB-Mal.

12 elimit the study to pure proton transfer and nonfluorescent acids, which allowed restricting the quen

13 eines were protected with the impermeant and nonfluorescent agent, methanethiosulfonate ethyltrimethy

14 de generated by pyruvate oxidase reacts with nonfluorescent Amplex Red at a 1:1 stoichiometry to form

15 Fluorescent markers and nonfluorescent analytes are initially mixed homogenously

16 ers of mobilities designed to bound those of nonfluorescent analytes of interest.

17 ytes can be used for detection of unlabeled (nonfluorescent) analytes.

18 orescence-activated cell sorting reverted to nonfluorescent and fluorescent phenotypes when placed in

19 that can be repeatedly photoswitched between nonfluorescent and fluorescent states, photobleaching li

20 Unbound dye is essentially nonfluorescent and has a large extinction coefficient (6

21 This species is nonfluorescent and has an absorbance maximum of 382 nm.

22 d were chosen so that the substrate would be nonfluorescent and the product fluorescent.

23 y blotting IEF was employed to monitor dark (nonfluorescent) and bright (fluorescent) GFP populations

24 ls, even when contaminating particles (i.e., nonfluorescent) are present.

25 d that the neutral lipid increased the total nonfluorescent area at surface pressures up to 25 mN/m b

26 the opposite effect of decreasing the total nonfluorescent area.

27 ve state, the reporter probe was essentially nonfluorescent at 700 nm due to energy resonance transfe

28 n band and large Stokes shift from initially nonfluorescent (BA)(4) AgBiBr(8) (BA=CH(3) (CH(2) )(3) N

29 Here we describe a reversibly switchable nonfluorescent bacterial phytochrome for use in multisca

30 s a synthetic chymotrypsin substrate that is nonfluorescent before cleavage by chymotrypsin, but is i

31 These nonfluorescent benzofurazan sulfides react rapidly and s

32 resolution 3D images of both fluorescent and nonfluorescent biological specimens with a thickness of

33 eans to visualize the immobilization even of nonfluorescent biomolecules.

34 hich the tumors are first pretargeted with a nonfluorescent biotinylated monoclonal antibody [cetuxim

35 oxidative C = C bond cleavages and converted nonfluorescent bis(DTF)-PI into highly fluorescent diald

36 es turn into the emissive red phase from the nonfluorescent blue phase.

37 nit oxidized and the other reduced), and the nonfluorescent (both subunits reduced).

38 In aqueous solution, the probe is almost nonfluorescent but displays significant fluorescence enh

39 bution was found within the population, with nonfluorescent cells showing a much lower PCN (</=1) tha

40 two distinct subpopulations, fluorescent and nonfluorescent cells.

41 een prepared; in contrast to their virtually nonfluorescent character in most environments, the meroc

42 ed schemes can be used to indirectly measure nonfluorescent chemicals in microscopic domains.

43 Nonfluorescent chlorophyll catabolites (NCCs) were descr

44 uorescent chlorophyll catabolites (FCCs) and nonfluorescent chlorophyll catabolites (NCCs).

45 escence, chlorophyll (Chl) is broken down to nonfluorescent chlorophyll catabolites (NCCs).

46 dition, we demonstrate that the release of a nonfluorescent chromophore via disulfide cleavage and su

47 nt to fluorescence microscopy for imaging of nonfluorescent chromophores and certain fluorophores.

48 This approach allows for the imaging of nonfluorescent chromophores and is generalizable to any

49 orter molecules such as fluorescent dyes and nonfluorescent chromophores utilizing acylhydrazone form

50 When the nonfluorescent chromoprotein asFP595 from Anemonia sulca

51 65 tripeptide, closely resembles that of the nonfluorescent chromoprotein Rtms5 in that the configura

52 s a diazoketone to lock the rhodamine in the nonfluorescent closed form, which can be activated with

53 The distinction between fluorescent and nonfluorescent colonies was exploited as a scorable phen

54 increases with increasing concentration of a nonfluorescent competitor ss DNA (d(T5-AT4AT5)) (C), ind

55 , the tetrapyrrole substrate, is a colorless nonfluorescent compound.

56 cin) and (ii) the ability to monitor cold or nonfluorescent compounds in a drug discovery setting.

57 ifferent analytes, including fluorescent and nonfluorescent compounds, with a variety of structures w

58 s, coupled with their tendency to cyclize to nonfluorescent configurations, precludes their use in vo

59 1 ratio between cis (fluorescent) and trans (nonfluorescent) conformations.

60 their specific interaction with Ac-Tempo, a nonfluorescent conjugate of fluorogenic acridine with pa

61 si disappeared abruptly at a transition to a nonfluorescent core continuous with the hair shaft.

62 FAs mimicked many properties of their native nonfluorescent counterparts, including uptake, distribut

63 while background cysteines are blocked with nonfluorescent covalent modifiers.

64 was prevented or reversed by addition of the nonfluorescent COX inhibitor (S)-flurbiprofen.

65 Subsequent click reactivity with nonfluorescent dansyl azide results in a 70-fold fluores

66 molecular constitution of the most abundant nonfluorescent DCC (NDCC), At-NDCC-1, was determined.

67 tion of Amplex Red, which is a colorless and nonfluorescent derivative of dihydroresorufin, produces

68 s: diazabenzoindoles, which remain virtually nonfluorescent, despite having a similar, rigid structur

69 ression of the different monolayers produced nonfluorescent domains that emerged for temperatures bet

70 nd repaired with grafts from strain-matched, nonfluorescent donors and secured in place with fibrin g

71 romophore-removed FLINC (DrFLINC), where the nonfluorescent Dronpa can nevertheless enhance TagRFP-T

72 e to the difficulty in imaging and measuring nonfluorescent drug molecules at a subcellular resolutio

73 Continuous measurement of efflux of nonfluorescent drugs on the same cell culture in situ, o

74 ive cells and fluorescently stained by small nonfluorescent dye molecules added from outside the cell

75 We report here a novel, water-soluble, nonfluorescent dye that efficiently quenches fluorescenc

76 Specifically, a nonfluorescent dye, BCECF-AM, is able to penetrate both

77 ion in the presence of a strongly absorbing, nonfluorescent dye.

78 Dark fluorescence quenchers are nonfluorescent dyes that can modulate the fluorescence s

79 technique is extensible to a wide variety of nonfluorescent dyes.

80 d and activate the fluorescence of otherwise nonfluorescent dyes.

81 een fluorescent protein from a background of nonfluorescent E. coli cells and shown that the bacteria

82 imental mixtures composed of fluorescent and nonfluorescent endocrine disruptors were analyzed.

83 mical assay format for the immobilization of nonfluorescent enzyme substrate, Leucine-GlutamicAcid-Hi

84 tocatalyst, amplifies itself by activating a nonfluorescent eosin Y derivative (EYH(3-)) under green

85 .8 microM) is comparable to that of cAMP and nonfluorescent Epac-selective agonist 8-(4-chlorophenylt

86 PvdP converts the nonfluorescent ferribactin, containing two iron binding

87 action within the material that converts the nonfluorescent film into a globally fluorescent material

88 ctural similarities between luciferase and a nonfluorescent flavoprotein, which is expressed in the l

89 In the second, caged (nonfluorescent) fluorescein-dextran was microinjected in

90 e to their propensity to adopt a lipophilic, nonfluorescent form.

91 atment with trifluoroacetic acid, the closed nonfluorescent forms of the dyes (2C and 2D) ring-opened

92 s article is to highlight the versatility of nonfluorescent Forster resonance energy transfer (FRET)

93 on, in which fluorescence is produced by two nonfluorescent fragments (N and C) of cyan fluorescent p

94 c RNA reporter, Broccoli, was split into two nonfluorescent fragments and conjugated to the end of tw

95 protein-fragment complementation, using two nonfluorescent fragments derived from fluorescent protei

96 ssay is based on the association between two nonfluorescent fragments of a fluorescent protein when t

97 Nonfluorescent fragments of the fluorescent protein Venu

98 is based on the complementation between two nonfluorescent fragments of the yellow fluorescent prote

99 ncorporation ratios (IRs=1.9 and 3.8) of the nonfluorescent FRET acceptor, K(D) values of 0.04+/-0.02

100 DNA sequencing analysis of nonfluorescent GFP clones indicated that the mutations i

101 ed on functional complementation between two nonfluorescent GFP fragments, can be used to detect the

102 extrinsic probe positions in the presence of nonfluorescent GM1.

103 Thus, formation of nonfluorescent ground-state hydrogen-bond complexes betw

104 Pc's possess a propensity to form nonfluorescent H-dimers that is utilized as the molecula

105 We prepared CHO cell lines expressing nonfluorescent halves (YN and YC) of yellow fluorescent

106 indolizine (RhIndz) spirolactone product was nonfluorescent; however, upon opening of the lactone rin

107 ugh a 1,2,3-triazole moiety, was essentially nonfluorescent in aqueous solutions.

108 he green fluorescent protein chromophore are nonfluorescent in solution but demonstrate a bright emis

109 pyr-1 diacetate (DA-ZP1-TPP), is essentially nonfluorescent in the metal-free state; however, exposur

110 The aldehydes are almost nonfluorescent in water, but addition of primary amines

111 ed by the activation illumination intensity; nonfluorescent inactive molecules are activated by a hig

112 he initial photochemical step, which forms a nonfluorescent intermediate absorbing at 696 nm (A696).

113 ther shows the antioxidant reactivity of the nonfluorescent intermediate semiquinone.

114 reaction, which can occur below 200 K, is a nonfluorescent intermediate with a broad absorbance band

115 e-resolved studies confirmed the presence of nonfluorescent intramolecular H-aggregates that increase

116 sidues in the chain, forming fluorescent and nonfluorescent intrastrand crosslinks, respectively.

117 Nonfluorescent, ionic nanocrystals (NCs) of CdSe were co

118 Resazurin (blue and nonfluorescent) is reduced to resorufin (pink and highly

119 Determined pIC(50)s for nonfluorescent JNK-1 inhibitors were also consistent wit

120 pt study to apply SERS-based detection using nonfluorescent labels to investigate alternative gene sp

121 A four-plex detection scheme using nonfluorescent labels was demonstrated for DNA sequences

122 Nonfluorescent labels were used for an array-format mult

123 erved under most reaction conditions was the nonfluorescent lactam form of the originally fluorescent

124 itrogen atoms forces the molecule to adopt a nonfluorescent lactone form, providing a convenient meth

125 receptor-Gialpha2 fusion protein, and with a nonfluorescent ligand and receptor-GFP fusion protein.

126 saturation of the receptor binding site with nonfluorescent ligand and use of a null-reactive CCK rec

127 h either radiolabeled ligand binding assays (nonfluorescent ligands) or fluorescence intensity assays

128 By combining nonfluorescent links with dilute mixtures of red, green,

129 Upon fusion of a nanodisc with a nonfluorescent liposome containing cognate proteins (for

130 fluorescent protein, and of fluorescent and nonfluorescent M3-M4 loops.

131 ple FRET (OS-FRET) method employing a novel, nonfluorescent methanethiosulfonate-linked acceptor that

132 2-photon microscopy, we found that 4-MUG (a nonfluorescent molecule) undergoes conversion into 4-MU

133 Dihydroresorufin is a nonfluorescent molecule, which can be electrochemically

134 cence fluctuations, and when fluorescent and nonfluorescent molecules compete for surface binding sit

135 nsity, the concentrations of fluorescent and nonfluorescent molecules in solution, the solution diffu

136 tiate intramolecular cyclization and convert nonfluorescent molecules to highly fluorescent products.

137 iation rate constants of the fluorescent and nonfluorescent molecules, the surface site density, the

138 s can result in usefully high emission from "nonfluorescent" molecules and million-fold increases in

139 soluble peptides reacted slowly, generating nonfluorescent monooxygenated and dioxygenated products.

140 highly fluorescent photoproduct as well as a nonfluorescent monooxygenated photoproduct.

141 lyzed reaction between hydrogen peroxide and nonfluorescent N-acetyl-3,7-dihydroxyphenoxazine (Amplex

142 nd a photo-insensitive molecule (Amber) as a nonfluorescent (N) place holder: namely, NDAN, NDNA, and

143 luorescent NAD(P)H are assayed directly, and nonfluorescent NAD(P) are enzymatically reduced to their

144 The dye self-assembles to form nonfluorescent nanoparticles (Dh = 200 nm) which selecti

145 th affinity and specificity similar to their nonfluorescent natural counterparts.

146 We speculate that it is a nonfluorescent nonultraviolet active cross-link between

147 Photoactivation of nonfluorescent NQMP-caged 3-allyloxyfluorescein produces

148 he absolute binding density of the ligand on nonfluorescent nucleic acid is independent of a priori k

149 uced transitions between fluorescent on- and nonfluorescent off-states.

150 es between two different states, typically a nonfluorescent "off" state and a fluorescent "on" state

151 s present in the enzyme have been changed to nonfluorescent ones in various combinations without majo

152 have been performed because they either are nonfluorescent or lack an ionizable OH group.

153 hese amines and their imine derivatives were nonfluorescent or very weakly fluorescent.

154 tion of resazurin termed AlamarBlue from its nonfluorescent oxidized state to its fluorescent reduced

155 The nonfluorescent PDM-NO exhibits a turn-on response toward

156 When the nonfluorescent peptide amphiphile component is designed

157 phile, and the second molecule is a shorter, nonfluorescent peptide amphiphile of complementary charg

158 e is hindered, and the compound remains as a nonfluorescent peptide conjugate.

159 ER delivery of a nonfluorescent peptide was demonstrated using a mAb high

160 te the NADH-driven oxidation of a colorless, nonfluorescent phenoxazine dye (Amplex Red) to a brightl

161 nedimethylimidazolinone (BDI) dye, is nearly nonfluorescent (Phif < 0.001) in common solutions at roo

162 ding constants (cellular K(i) values) of the nonfluorescent phorbol ester PDBu and the anticancer age

163 rane organelles filled with melanin, a dark, nonfluorescent pigment.

164 FRET was diminished upon addition of nonfluorescent pre-SufI, indicating that the initial bin

165 f cathepsin K in complex with ABP 25 and its nonfluorescent precursor 21 were determined to character

166 ntails generating a fluorescent probe from a nonfluorescent precursor, 4-ethynyl-N-ethyl-1,8-naphthal

167 an in situ formation of a fluorophore from a nonfluorescent precursor.

168 ifies structures labeled with fluorescent or nonfluorescent probes.

169 neous transformation of resorufin to less or nonfluorescent product(s) in the absence of hydrogen per

170 by metabolically active cells led to a final nonfluorescent product, and hence an underestimation of

171 sed on the chlorination of resorcinol to its nonfluorescent products in the presence of HOCl.

172 However, the flavin binding sites of the nonfluorescent protein are likely not representative of

173 We deduce the fraction of nonfluorescent proteins for EGFP, mRFP, and mCherry as w

174 159 and Cys171, locking the chromophore in a nonfluorescent protonated state.

175 cation and classification of fluorescent and nonfluorescent pseudomonads.

176 After its synthesis in the cytoplasm, the nonfluorescent pyoverdine precursor ferribactin is expor

177 Here we report the use of a nonfluorescent quencher (Black Hole Quencher, BHQ) as an

178 rophore of the desired emission color, and a nonfluorescent quencher.

179 donor, and the beta-clamp was labeled with a nonfluorescent quencher.

180 Our results illustrate the potential of nonfluorescent quenchers in single-molecule correlation

181 d, 6-TAMRA) near the carboxyl terminus and a nonfluorescent quenching group (QSY-7) near the amino te

182 re and carries a 5'-fluorescent moiety, a 3'-nonfluorescent quenching moiety, and an appropriate clea

183 duct of the initial light-driven reaction, a nonfluorescent radical species, into a new intermediate

184 rface-enhanced Raman scattering (SERS) using nonfluorescent Raman labels to quantify gene expression

185 ntrolled through the surface coverage of the nonfluorescent Raman tags (RTags).

186 alently attach both DNA probing sequence and nonfluorescent Raman tags to the surface of gold nanopar

187 loyed for indirectly detecting absorbing but nonfluorescent reagents in microsamples, employing inner

188 a DMB, and (2) we monitored DMB delivery of nonfluorescent reagents into droplets preloaded with LY.

189 emission or absorption contrast, permitting nonfluorescent reporters for molecular imaging.

190 escent product resorufin at pH 7.0 or to the nonfluorescent resazurin at pH 4.0.

191 ons, and enzymatic oxidation of resorufin to nonfluorescent resazurin.

192 the beta-galactosidase-catalyzed reaction of nonfluorescent resorufin-beta-D-galactopyranoside to yie

193 -to-superficial pathway was not sensitive to nonfluorescent retrograde tracers including horseradish

194 Competitive binding experiments with nonfluorescent RNC species revealed that the nascent cha

195 ly accomplished with a long-term goal to use nonfluorescent RTags in a Raman-based DNA microarray pla

196 scherichia coli DnaB helicase to unmodified, nonfluorescent single-stranded nucleic acids where the i

197 defects surrounding the probe NV, including nonfluorescent "single-charge emitters" that would other

198 Here we map the adsorption of nonfluorescent small molecule/ion and polymer ligands on

199 For the DMPC/DSPC we found that the nonfluorescent solid regions gradually disappear in the

200 emonstrated that the oxidation reaction of a nonfluorescent species at the working electrode can be q

201 achieve separation and indirect detection of nonfluorescent species using fluorescent mobility marker

202 ethylrhodamines (AnMR) maintain a colorless, nonfluorescent spirocyclic structure at high pH.

203 ly high concentrations of Zn(ClO(4))(2), the nonfluorescent spirolactam component of 4 is transformed

204 d below the focal plane are transferred to a nonfluorescent state at each scanning step.

205 y between the half-fluorescent state and the nonfluorescent state.

206 ched between a green fluorescent state and a nonfluorescent state.

207 reversibly converted between fluorescent and nonfluorescent states have proven to be a catalyst for i

208 n both the fluorescent and the light-induced nonfluorescent states reveal that the rapid and complete

209 stic, optical control of its fluorescent and nonfluorescent states, and subsequently applying a lock-

210 Two nonfluorescent states, D1 and D2, exist in a voltage-dep

211 by a highly selective thioether spirocyclic nonfluorescent structure that opens to form a mixture of

212 esults showed that nanoceria can oxidize the nonfluorescent substrate ampliflu, either to the very st

213 quenched in the protein, yielding virtually nonfluorescent substrate molecules.

214 ese results are applicable to natural (i.e., nonfluorescent) substrates.

215 es and precipitates) but also to essentially nonfluorescent systems (due to pai-pai aggregation).

216 The nonfluorescent terphenyl diazoketone 1 was transformed i

217 relies on the hematin-catalyzed oxidation of nonfluorescent thiamine to fluorescent thiochrome by H2O

218 ior exposure of cells to the impermeable and nonfluorescent thiol-specific agent ethyltrimethylammoni

219 "highlighters", which can be converted from nonfluorescent to fluorescent or from one color to anoth

220 se, primer extension by DNA polymerase using nonfluorescent TPLFNs generates fluorophores, which are

221 lemented with iron gave increased numbers of nonfluorescent trichomonads.

222 dy (MAb) to P270 yields both fluorescent and nonfluorescent trichomonads.

223 45 protein containing 4-fluorotryptophan, a nonfluorescent tryptophan analogue, subunit exchange bet

224 lysis of the PriA helicase interactions with nonfluorescent, unmodified nucleic acids has been perfor

225 lysis of the DnaB helicase interactions with nonfluorescent, unmodified nucleic acids has been perfor

226 signed small ligand is membrane-permeant and nonfluorescent until it binds with high affinity and spe

227 ped with rhodamine spirolactam dyes that are nonfluorescent until they encounter mercury ions, which

228 o3 or pyrene maleimide, that are essentially nonfluorescent until they react with a thiol.

229 was localized in the cytoplasm, whereas the nonfluorescent version was localized to the periplasmic

230 g vesicles were vastly outnumbered by older, nonfluorescent vesicles.

231 istic of an H-aggregate that was practically nonfluorescent, whereas in organic media, they displayed

232 ar dyes bearing eight fused rings are almost nonfluorescent, which is attributed to fast internal con

233 ue-green region of the spectrum, while 4c is nonfluorescent, which is likely attributable to an intra

234 Dipyrrinones are nonfluorescent yellow-pigmented constituents of bilirubi

235 tion of Nef with a partner kinase juxtaposes nonfluorescent YFP fragments fused to the C terminus of

236 Cation exchange (CX) in the nonfluorescent ZnS nanocrystal clusters (NCCs) was emplo