ライフサイエンスコーパス: nonreducing end

1 Sia alpha 2-6Gal or Sia alpha 2-3Gal at the nonreducing end.

2 and CBH II) preferentially cleaves from the nonreducing end.

3 ccharides with Delta-4,5-unsaturation at the nonreducing end.

4 only lack the galactose residue at the Le(a) nonreducing end.

5 y added to the fifth xylose residue from the nonreducing end.

6 ched to the phosphoethanolamine group at the nonreducing end.

7 eavage occurred from the reducing end or the nonreducing end.

8 to a growing chain of polysialic acid at the nonreducing end.

9 acid (HA) by addition to the reducing or the nonreducing end.

10 tment with beta-glycosidases that act at the nonreducing end.

11 ainly to the second glucose residue from the nonreducing end.

12 ly degraded from the reducing end toward the nonreducing end.

13 ivity and degrades the chitin chain from the nonreducing end.

14 nzyme contain a C4 gemdiol/keto group at the nonreducing end.

15 erified to a variety of mycolic acids at the nonreducing ends.

16 ific sulfates and monosaccharides from their nonreducing ends.

17 of the terminal trisaccharide, having at the nonreducing end a GlcNAc or GalNAc, and bound them to BS

18 1 at the residues immediately located at the nonreducing end, allowing the formation of an N-Ac domai

19 ing N-acyl and O-acetyl modifications at the nonreducing end and a critical 6-O-sulfate at the reduci

20 igosaccharides containing a galactose at the nonreducing end and a propargyl group at the reducing en

21 ccharides of N-glycan with a GlcNAc at their nonreducing end and found that the extended sugar moiety

22 ontaining an unsaturated uronate unit at the nonreducing end and two contiguous AT-binding sequences

23 binding subsites (-I, -II, and -III) for the nonreducing end and two glucose binding subsites (+I and

24 ity of the enzyme by impeding nonproductive (nonreducing end) binding.

25 The disaccharide at the nonreducing end binds specifically; the other rings are

26 multiple positions or exolytically from the nonreducing end by one or three glucose units at a time,

27 oside hydrolase Family 6 (GH6) CBHs act from nonreducing ends by an inverting mechanism and are prese

28 of glycosyl hydrolases (GH5) and by Cel6A, a nonreducing-end cellobiohydrolase from family GH6 with t

29 evans and to differentiate reducing-end from nonreducing end cross ring cleavages in levans.

30 Also, nonreducing end de-N-acetyl residue-enriched vaccines el

31 >/=1/10,000), but only vaccines enriched for nonreducing end de-N-acetyl residues by treatment with e

32 n and minimally to an altered binding of the nonreducing-end DEF trisaccharide to the native serpin c

33 results suggest that glycosidases acting on nonreducing ends digest large amounts of xyloglucan in w

34 erminal 4,5-unsaturated glucuronic acid, the nonreducing end disaccharide moiety does not interact wi

35 e closely associated with positioning of the nonreducing end during catalysis.

36 also confirming that growth occurred at the nonreducing end following initiation on phosphatidylglyc

37 ains has to proceed from the reducing to the nonreducing end for a better yield.

38 ed UDP-sugars, consistent with growth at the nonreducing end for this enzyme.

39 h the azido group at the C-6 position of the nonreducing end fucose could elicit a strong IgG immune

40 d alpha2-3- or alpha2-6-linked to a terminal nonreducing end galactose, poly-LacNAc extended core-3 O

41 harides contained N-acetylglucosamine at the nonreducing ends, galactosylation was judged to be ineff

42 plex with an oligosaccharide acceptor with a nonreducing end GlcNAc that has a beta1-6-glycosidic lin

43 e 5'-diphospho-beta-l-fucose (GDP-Fuc), to a nonreducing end glucose, creating an alpha-(1->4) linkag

44 We also show that the carboxyl group on nonreducing end glucuronic acid in dodecasaccharide moti

45 sthydrolysis state in which the newly formed nonreducing end has already left the substrate binding p

46 monitored for drug exposure; total HS and HS nonreducing end (HS-NRE) levels in both cerebrospinal fl

47 ndicated that ligands bound to E2 with their nonreducing ends in position -2, consistent with the pos

48 the reducing end of cellobiose, leaving the nonreducing end intact in these products.

49 and masked as a 1,6-anhydro sugar, while the nonreducing end is activated as a free alkyne and masked

50 type that could be explained by an excess of nonreducing ends leading to a reinforced xyloglucan netw

51 des involving unsaturated uronic acid at the nonreducing end linked to rhamnose-3-sulfate and glucuro

52 stic of neuraminic acid, particularly at the nonreducing end, may be important for processing and pre

53 s contain neither the galactose at the Le(a) nonreducing end nor the fucose at the Le(x) reducing end

54 ide evidence that NS domains residing at the nonreducing end (NRE) are, on average, longer than those

55 ohydrate-binding module (CBM) that binds the nonreducing end of beta-1,3-glucan chains, and an unchar

56 te displace the 6-hydroxymethyl group of the nonreducing end of both acarbose and D-gluco-dihydroacar

57 hibit specificity for either the reducing or nonreducing end of cellulose.

58 ution reveals that the GlcNAc residue at the nonreducing end of chitobiose makes extensive hydrophobi

59 n (GH18(C)) and releases chitobiose from the nonreducing end of chitooligosaccharides, therefore func

60 Steric contacts between the nonreducing end of D-gluco-dihydroacarbose and the catal

61 fate from N-sulfoglucosamine residues on the nonreducing end of heparan sulfate (HS-NRE) within lysos

62 ked alpha-D-galacturonosyl residues onto the nonreducing end of homogalacturonan chains.

63 lowed by a cluster of alpha-helices, and the nonreducing end of maltooligosaccharides can be captured

64 samines present as monosaccharides or at the nonreducing end of odd-numbered oligosaccharide substrat

65 ronate or beta-D-manuronate residues, at the nonreducing end of oligo-alginates in an exolytic fashio

66 the unsaturated Delta4,5 uronic acid at the nonreducing end of oligosaccharides resulting from prior

67 Sialic acids (Sia) form the nonreducing end of the bulk of cell surface-expressed gl

68 y to HC2 and both are near the less sulfated nonreducing end of the CS.

69 he C-6 position of the GlcNAc residue at the nonreducing end of the disaccharide.

70 ucing an azido-containing sialic acid to the nonreducing end of the galactosides through a sialyltran

71 The nonreducing end of the glycan is terminated with the cap

72 lternate additions of Glc and GlcUA onto the nonreducing end of the growing polysaccharide chain.

73 l" antithrombin binding site and also at the nonreducing end of the molecule, which is reported in in

74 udes a 3,6-dideoxyhexose, ascarylose, as the nonreducing end of the O-antigen tetrasaccharide.

75 initiated by subsite 1 interactions with the nonreducing end of the oligosaccharide substrate, minimi

76 ing if a GalNAc-4S residue is reached on the nonreducing end of the oligosaccharide.

77 A2 binds up to five sugar residues from the nonreducing end of the oligosaccharide.

78 luronic acid blocks from the reducing to the nonreducing end of the polymer following the initial ran

79 e 3 polysaccharide was shown to occur at the nonreducing end of the polysaccharide chain.

80 4, where the (GlcNAc)2 group arises from the nonreducing end of the substrate and is formed as the be

81 The nonreducing end of the substrate-binding site of human s

82 The nonreducing end of the sugar is positioned near the prot

83 nit MalF binds three glucosyl units from the nonreducing end of the sugar.

84 The nonreducing end of the xylose moiety of xylobiose binds

85 d a new dehydratase (P29_PDnc) acting on the nonreducing end of ulvan oligosaccharides, i.e., GlcA/Id

86 meric enzyme that releases fructose from the nonreducing end of various oligosaccharides and essentia

87 plex predicts transfer of GPI-CWP toward the nonreducing ends of acceptor glycans in the cell wall.

88 aditionally as releasing cellobiose from the nonreducing ends of cellulose, but this definition is in

89 by W58L was confirmed from both reducing and nonreducing ends of CNP-labeled oligosaccharide substrat

90 and sites farther away from the reducing and nonreducing ends of oligosaccharide substrates.

91 Importantly, both reducing and nonreducing ends of the bound ligand are completely expo

92 and 2-O-sulfo-iduronic acid residues at the nonreducing ends of the glycans as co-receptors for Shh.

93 ity of the fragmentation originates from the nonreducing ends of the glycans.

94 e modes by recognizing the structures of the nonreducing ends of the substrates.

95 ith its C-terminus free and the GPI with its nonreducing end phosphoethanolamine bearing a free amino

96 gosaccharides with the sulfate esters at the nonreducing ends preferentially bind to the lectin.

97 ars to cleave chitooligosaccharides from the nonreducing end primarily by disaccharide units.

98 Here we show that the nonreducing end product formed by an N. crassa PMO is a

99 and (GlcNAc)4 where dimers cleaved from the nonreducing end reflect the most common binding and hydr

100 In contrast, removal of the nonreducing- end residue D drastically affected the init

101 deletion of reducing-end residues G and H or nonreducing-end residue D produced variable losses in pe

102 These results demonstrate that the nonreducing-end residues of the pentasaccharide function

103 accumulated heparan sulfate exhibits unique nonreducing end structures with terminal N-sulfoglucosam

104 n bonding between Asn(462) and xylose at the nonreducing end subsite +2 was important for the higher

105 long-range stereoelectronic effects from the nonreducing end sugar can influence the reactivity of th

106 at 355 nm, producing fragment ions from the nonreducing end that do not contain the appended fluorop

107 hed to the phosphoethanolamine moiety at the nonreducing end to form GPI-linked peptides.

108 While assembly from the nonreducing end to the reducing end was more convergent

109 The enzyme sulfates the substrate from the nonreducing end toward the reducing end consecutively, l

110 hin sulfate (ECS), was designed to mimic the nonreducing end trisaccharide unit DEF of the sequence s

111 domain A binding site of CV-N than with the nonreducing end unit.

112 -O-, 5-O- and 3,5-di-O-linked alpha-Araf and nonreducing end-units of alpha-Araf, Arap, beta-Galp and

113 ed cellodextrins modified at the reducing or nonreducing ends upon incubation with cellulose and cell

114 alogues with modification at the reducing or nonreducing end were synthesized using chemoenzymatic me

115 investigated on cellopentaose labeled at the nonreducing end with 14C, and cellooligosaccharides redu

116 hand, synthesis from the reducing end to the nonreducing end yielded the mannopentaose with the desir