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1 ion, we have identified for the first time a nonsteroidal agent that selectively activates beta1-cont
2 lofexor (formerly GS-9674), a small-molecule nonsteroidal agonist of farnesoid X receptor, in patient
3 gimens in patients with prior sensitivity to nonsteroidal AI and in baseline plasma from the PALOMA3
6 d crystal structure of the GR LBD bound to a nonsteroidal antagonist, and this article provides addit
8 d intracellular CYP450 on the removal of six nonsteroidal anti-inflammatories (NSAIs) by Trametes hir
9 drugs in five different classes (uricosuric, nonsteroidal anti-inflammatories, loop diuretics, angiot
12 k have often included patients using aspirin/nonsteroidal anti-inflammatory agents (NSAIDs) or acid-s
15 hol-related conditions), and medication use (nonsteroidal anti-inflammatory agents, corticosteroids,
16 rvations: Regional analgesia, acetaminophen, nonsteroidal anti-inflammatory agents, gabapentinoids, t
17 the relationship between early postoperative nonsteroidal anti-inflammatory drug (NSAID) administrati
20 l carbonic anhydrase inhibitor in 6 eyes and nonsteroidal anti-inflammatory drug (NSAID) drops in 2 e
23 en single nucleotide polymorphisms (SNPs) in nonsteroidal anti-inflammatory drug (NSAID) metabolism a
25 tive net arylation of the minimally modified nonsteroidal anti-inflammatory drug (NSAID) naproxen.
26 al prednisolone acetate (PA) alone or with a nonsteroidal anti-inflammatory drug (NSAID) or intraoper
27 y examined whether short-term use of topical nonsteroidal anti-inflammatory drug (NSAID) or steroid t
28 ng body of evidence links certain aspects of nonsteroidal anti-inflammatory drug (NSAID) pharmacology
29 K-80003, a tRXRalpha modulator derived from nonsteroidal anti-inflammatory drug (NSAID) sulindac, su
30 s between the microbiota and indomethacin, a nonsteroidal anti-inflammatory drug (NSAID) that inhibit
31 PT; aspirin/clopidogrel, ticagrelor) but not nonsteroidal anti-inflammatory drug (NSAID) treatment wi
32 l trials have showed no relationship between nonsteroidal anti-inflammatory drug (NSAID) use and AD.
34 ty analyses by repeating the analyses in non-nonsteroidal anti-inflammatory drug (NSAID) users (n = 3
35 (II)-phenanthroline complexes containing the nonsteroidal anti-inflammatory drug (NSAID), indomethaci
36 This study demonstrates that daily use of a nonsteroidal anti-inflammatory drug (NSAID), which inhib
38 tro test to either diagnose or differentiate nonsteroidal anti-inflammatory drug (NSAID)-exacerbated
40 landin E(2) (PGE(2) ) has been postulated in nonsteroidal anti-inflammatory drug (NSAID)-exacerbated
42 and anticancer evaluation of novel selenium-nonsteroidal anti-inflammatory drug (Se-NSAID) hybrid mo
43 large effusion or tamponade, and failure of nonsteroidal anti-inflammatory drug [NSAID] treatment) i
44 idence of risk transformation during chronic nonsteroidal anti-inflammatory drug administration, this
46 K3 channels (A237T) or by application of the nonsteroidal anti-inflammatory drug flufenamic acid (FFA
47 the fragrance component celestolide and the nonsteroidal anti-inflammatory drug ibuprofen, are descr
48 identified a context-dependent effect of the nonsteroidal anti-inflammatory drug indomethacin (IND) o
53 , be physically active, not smoke, and avoid nonsteroidal anti-inflammatory drug use except aspirin p
54 s and the 2007 recommendation on aspirin and nonsteroidal anti-inflammatory drug use to prevent color
55 ching yielded 6,088 statin user pairs, 2,886 nonsteroidal anti-inflammatory drug user pairs, 1,440 gl
56 r statin users, 1.00 (95% CI, 0.90-1.11) for nonsteroidal anti-inflammatory drug users, 0.97 (95% CI,
57 statin users, 21.3% (95% CI, 19.8-22.9%) for nonsteroidal anti-inflammatory drug users, 17.4% (95% CI
60 ment goals are not met, a trial of a topical nonsteroidal anti-inflammatory drug, tramadol, or both i
61 methylation and deuteration of nimesulide, a nonsteroidal anti-inflammatory drug, were realized throu
66 uished: NSAID-exacerbated cutaneous disease, nonsteroidal anti-inflammatory drug-induced urticaria/an
70 4.81-5.64), steroids (3.18; 2.99-3.39), and nonsteroidal anti-inflammatory drugs (2.37; 2.26-2.48) w
71 ocal anesthesia (31.1% vs 12.9%; P < 0.001), nonsteroidal anti-inflammatory drugs (33.5% vs 14.4%; P
72 lume, followed by topical steroids (86%) and nonsteroidal anti-inflammatory drugs (66%), and accounte
73 rent use of antihypertensive medications and nonsteroidal anti-inflammatory drugs (adjusted odds rati
75 tions, and 17 of bronchospasm related to ASA/nonsteroidal anti-inflammatory drugs (NSAID) intake.
76 or alcohol consumption, co-administration of nonsteroidal anti-inflammatory drugs (NSAID) or concomit
77 mide antibiotics (7.4%), opiates (6.8%), and nonsteroidal anti-inflammatory drugs (NSAIDs) (3.5%).
78 19), NAR against aspirin (n = 12) and other nonsteroidal anti-inflammatory drugs (NSAIDs) (n = 8), a
79 ere included: 10 trials evaluated the use of nonsteroidal anti-inflammatory drugs (NSAIDs) (n=4,258)
80 ly to experience IOP spikes than those using nonsteroidal anti-inflammatory drugs (NSAIDs) alone (haz
81 ing acute or chronic pains or inflammations, nonsteroidal anti-inflammatory drugs (NSAIDs) also assoc
85 For treatment of malignant pleural effusion, nonsteroidal anti-inflammatory drugs (NSAIDs) are avoide
88 lusive data about cardiovascular toxicity of nonsteroidal anti-inflammatory drugs (NSAIDs) are sparse
91 related anaphylaxis induced by LTPs requires nonsteroidal anti-inflammatory drugs (NSAIDs) as a trigg
97 to aspirin (acetylsalicylic acid) and other nonsteroidal anti-inflammatory drugs (NSAIDs) constitute
99 infarction (MI); however, concomitant use of nonsteroidal anti-inflammatory drugs (NSAIDs) could pose
100 drugs such as acetaminophen/paracetamol and nonsteroidal anti-inflammatory drugs (NSAIDs) for mild c
106 enefit the most from using aspirin and other nonsteroidal anti-inflammatory drugs (NSAIDs) in relatio
113 escribe the effect of routine use of topical nonsteroidal anti-inflammatory drugs (NSAIDs) on the inc
114 s document for hypersensitivity reactions to nonsteroidal anti-inflammatory drugs (NSAIDs) proposed b
115 ND & AIMS: Use of aspirin and/or non-aspirin nonsteroidal anti-inflammatory drugs (NSAIDs) reduces th
118 have demonstrated the remarkable efficacy of nonsteroidal anti-inflammatory drugs (NSAIDs) such as ib
121 racted attention due to prior conjugation to nonsteroidal anti-inflammatory drugs (NSAIDs) to access
123 d that acute respiratory infection (ARI) and nonsteroidal anti-inflammatory drugs (NSAIDs) use could
125 ials evaluating the cardiovascular safety of nonsteroidal anti-inflammatory drugs (NSAIDs) when used
126 back, musculoskeletal injuries with topical nonsteroidal anti-inflammatory drugs (NSAIDs) with or wi
128 e placebo-controlled) shows that colchicine, nonsteroidal anti-inflammatory drugs (NSAIDs), and corti
129 e placebo-controlled) shows that colchicine, nonsteroidal anti-inflammatory drugs (NSAIDs), and corti
130 e of proton pump inhibitors (PPIs), aspirin, nonsteroidal anti-inflammatory drugs (NSAIDs), and selec
132 ribute to enteropathy associated with use of nonsteroidal anti-inflammatory drugs (NSAIDs), but there
133 g modes to equine serum albumin (ESA) of two nonsteroidal anti-inflammatory drugs (NSAIDs), diclofena
134 eview the recent literature on the safety of nonsteroidal anti-inflammatory drugs (NSAIDs), glucocort
135 undreds of millions of people worldwide take nonsteroidal anti-inflammatory drugs (NSAIDs), often in
136 ends that clinicians choose corticosteroids, nonsteroidal anti-inflammatory drugs (NSAIDs), or colchi
138 ve been evaluated for prophylaxis, including nonsteroidal anti-inflammatory drugs (NSAIDs), which are
139 arin with antiplatelet drugs or nonselective nonsteroidal anti-inflammatory drugs (NSAIDs), which fur
142 cantly decrease risks for SP included use of nonsteroidal anti-inflammatory drugs (RR, 0.77; 95% CI,
143 antihypertensives, 4 diabetes medications, 2 nonsteroidal anti-inflammatory drugs [NSAIDs] or aspirin
147 treated with potassium-sparing diuretics or nonsteroidal anti-inflammatory drugs and oral potassium
149 providing access to a variety of enantiopure nonsteroidal anti-inflammatory drugs and to alpha-amino
150 hol and smoking and taking analgesic agents (nonsteroidal anti-inflammatory drugs and weak opioids su
153 should consider pharmacologic treatment with nonsteroidal anti-inflammatory drugs as first-line thera
154 employment status, and use of analgesics and nonsteroidal anti-inflammatory drugs at 1 and 12 months.
155 r array is able to differentiate six typical nonsteroidal anti-inflammatory drugs at concentrations o
156 ted in the effluent exposome of fish, 6 were nonsteroidal anti-inflammatory drugs but with plasma con
157 hen was ineffective for acute low back pain, nonsteroidal anti-inflammatory drugs had smaller benefit
158 rmance in semiquantitative identification of nonsteroidal anti-inflammatory drugs has been investigat
159 trials (RCTs) showed that oral steroids and nonsteroidal anti-inflammatory drugs have similar analge
160 tended to arylpropionic acids (including the nonsteroidal anti-inflammatory drugs ibuprofen and flurb
161 advances in our understanding of the role of nonsteroidal anti-inflammatory drugs in CRC prevention a
165 ting that both ionized and neutral states of nonsteroidal anti-inflammatory drugs must be considered
166 BF4)3 and [Ru(NH3)5(L)](BF4)3 containing the nonsteroidal anti-inflammatory drugs nicotinic acid (Hni
167 sired, clinicians and patients should select nonsteroidal anti-inflammatory drugs or skeletal muscle
168 lls with pharmacological inhibitors, such as nonsteroidal anti-inflammatory drugs or small interferin
169 ts include oral contraceptives combined with nonsteroidal anti-inflammatory drugs or surgery to remov
170 ctures (OR, 2.65; 95% CI, 2.34-2.99), use of nonsteroidal anti-inflammatory drugs plus opioids (OR, 1
172 to cause cardiovascular adverse effects than nonsteroidal anti-inflammatory drugs specific for inhibi
173 estinal ulcers are common adverse effects of nonsteroidal anti-inflammatory drugs such as acetylsalic
178 in PBMCs, and supplementation of cells with nonsteroidal anti-inflammatory drugs was able to restore
181 rt A) or unspecified (cohort B) reactions to nonsteroidal anti-inflammatory drugs were identified as
182 , decreased hematocrit, aspirin therapy, and nonsteroidal anti-inflammatory drugs were independently
183 UV filters, personal sunscreen products, and nonsteroidal anti-inflammatory drugs were seen in both g
184 hese differential effects were ignored, oral nonsteroidal anti-inflammatory drugs were superior.
186 (age, sex, smoking, body mass index, use of nonsteroidal anti-inflammatory drugs) and symptoms of ga
187 s), avoidance of potential nephrotoxins (eg, nonsteroidal anti-inflammatory drugs), and adjustments t
188 ions (statins, aspirin, corticosteroids, and nonsteroidal anti-inflammatory drugs), with ulcerated pr
192 the injection, 14% administer post operative nonsteroidal anti-inflammatory drugs, 28% administer pos
193 asm after the ingestion of aspirin and other nonsteroidal anti-inflammatory drugs, a disorder termed
194 These patients are usually treated with nonsteroidal anti-inflammatory drugs, acetaminophen, opi
195 roxychloroquine, intravenous immunoglobulin, nonsteroidal anti-inflammatory drugs, and cyclosporine,
196 other antihypertensives, aspirin, steroids, nonsteroidal anti-inflammatory drugs, Charlson Comorbidi
197 -opioid interventions such as acetaminophen, nonsteroidal anti-inflammatory drugs, cyclooxygenase-2 i
198 -opioid interventions such as acetaminophen, nonsteroidal anti-inflammatory drugs, cyclooxygenase-2 i
199 is inhibited by ACA as well as the fenamate nonsteroidal anti-inflammatory drugs, flufenamate and ni
201 flammatory drugs such as corticosteroids and nonsteroidal anti-inflammatory drugs, often accompanied
202 casionally after the intake of drugs such as nonsteroidal anti-inflammatory drugs, opioids and drugs
203 h DILI (due to acetaminophen, phenprocoumon, nonsteroidal anti-inflammatory drugs, or autoimmune hepa
204 ion single-agent or combined use of statins, nonsteroidal anti-inflammatory drugs, or glucocorticoids
205 Intra-articular treatments were superior to nonsteroidal anti-inflammatory drugs, possibly because o
206 (solid or liquid), and potential cofactors (nonsteroidal anti-inflammatory drugs, protonic pump inhi
207 ave been studied include aspirin, nonaspirin nonsteroidal anti-inflammatory drugs, statins, agents th
208 h-sensitivity C-reactive protein, and use of nonsteroidal anti-inflammatory drugs, statins, and multi
209 ncer, and they are the molecular targets for nonsteroidal anti-inflammatory drugs, which are among th
220 vity reactions to beta-lactams, aspirin, and nonsteroidal anti-inflammatory drugs; however, the clini
222 eated postoperatively with topical steroids, nonsteroidal anti-inflammatory medications (NSAIDs), or
224 ation of two therapeutic drugs, benzydamine (nonsteroidal anti-inflammatory) and tamoxifen (antiestro
225 either open-label enzalutamide or a standard nonsteroidal antiandrogen therapy (standard-care group).
227 tion of the triazole core in the scaffold of nonsteroidal antiandrogens allowed the development of sm
229 element in the common A-ring-linkage-B-ring nonsteroidal antiandrogens' general pharmacophore allowe
230 logically active substances (antibacterials, nonsteroidal antiinflammatories, antiseptics, antiepilep
231 The present study compared the effect of the nonsteroidal antiinflammatory drug (NSAID) diclofenac, w
232 estinal damage in zebrafish larvae using the nonsteroidal antiinflammatory drug (NSAID) Glafenine.
235 3 effects to blockade by two analgesics (the nonsteroidal antiinflammatory drug ketoprofen and the mu
236 but not postoperative, administration of the nonsteroidal antiinflammatory drug ketorolac and/or reso
241 of nine measures of high-risk prescribing of nonsteroidal antiinflammatory drugs (NSAIDs) or selected
243 of celecoxib, as compared with nonselective nonsteroidal antiinflammatory drugs (NSAIDs), remains un
246 as weight (kg)/height (m)2), never-users of nonsteroidal antiinflammatory drugs, and those with lowe
250 looxygenase 2 inhibitors versus nonselective nonsteroidal antiinflammatory medications in 6-month gas
252 e small chemical changes in the structure of nonsteroidal AR ligands determine the pharmacological re
254 reported in the accompanying paper that the nonsteroidal compound CpdX as well as its deuterated for
256 ding-capacity assays, we report here how two nonsteroidal compounds bind to human SHBG, and how they
258 ent tumors, such as the steroidal STX140 and nonsteroidal counterparts, acting inter alia through mic
260 Herein, we report for the first time that a nonsteroidal drug, ormeloxifene, has potent anticancer p
262 ver some 20 years, have led to steroidal and nonsteroidal drugs in numerous preclinical and clinical
263 efficacy of cilofexor (formerly GS-9674), a nonsteroidal farnesoid X receptor agonist in patients wi
264 e-activity relationship (SAR) of a series of nonsteroidal glucocorticoid receptor (GR) agonists are d
265 Seven-day treatment with inhalation of the nonsteroidal glucocorticoid receptor agonist AZD5423 eff
270 sign and pharmacology of clinically relevant nonsteroidal GR antagonists that may have greater select
271 refined classic GCs or a novel generation of nonsteroidal GR-targeting molecules, to meet the increas
272 ective and efficient method of preparing the nonsteroidal, inhaled selective glucocorticoid receptor
275 dy was to identify and optimize 17beta-HSD14 nonsteroidal inhibitors as well as to disclose their str
278 C-ring, alone and in combination, as well as nonsteroidal mimics provided numerous potent VDR agonist
279 ated whether the administration of the novel nonsteroidal mineralocorticoid receptor (MR) antagonist
283 s effort, (R)-14c was identified as a potent nonsteroidal MR antagonist (IC50 = 4.5 nM) with higher t
284 restricted to steroidal MR antagonists as a nonsteroidal MR antagonist failed to reduced blood press
288 Orteronel (TAK-700) is an investigational, nonsteroidal, reversible, selective 17,20-lyase inhibito
290 reports have described the increasing use of nonsteroidal selective androgen receptor modulators, whi
291 gic evidence showed that AZD9496 is an oral, nonsteroidal, selective estrogen receptor antagonist and
294 Kidney Disease) evaluated the effect of the nonsteroidal, selective mineralocorticoid receptor antag
296 to identify bile acid mimetics we uncovered nonsteroidal small molecule scaffolds that bind and inhi
297 ification and characterization of AZD9496, a nonsteroidal small-molecule inhibitor of ERalpha, which
298 tory activities of a series of steroidal and nonsteroidal sulfamate derivatives against CA IX in comp
299 fundamental need to identify nonestrogen or nonsteroidal targets for the treatment of endometriosis.