ライフサイエンスコーパス: normal

1 ns, whereas photoreceptors of F45L mice were normal.

2 Physical examination was normal.

3 the disease and revert societal live back to normal.

4 germline ablated but otherwise structurally normal.

5 Thymic development of this population was normal.

6 lated to establish upper and lower limits of normal.

7 ors in vitro reduced phosphorylated STAT1 to normal.

8 ve of normalcy in the stage from abnormal to normal.

9 All compounds show normal (10-fold higher) molar CO(2) versus N(2) uptake a

10 e to migrate toward chemokines despite their normal ability to move randomly.

11 ed in VHL-deficient ccRCC tumors compared to normal adjacent tissue.

12 l basis of reinforcement-related behavior in normal adolescent development and psychopathology.

13 The normal age-related decline in proportions of submucosal

14 This study is the first to investigate normal ageing in these brain regions using 7T (1)H-MRS a

15 g in multiple sclerosis (MS) attributable to normal aging increased from 42.7% and 16.7% respectively

16 chers because of its involvement in both the normal aging process and common human diseases.

17 known mold growth ("moldy") differs from the normal airborne fungal ecology of homes with no history

18 ing tracers in order to reach a consensus on normal and abnormal tau imaging values that can be unive

19 identify novel inhibitors of ciliogenesis in normal and basal breast cancer cells.

20 the complex protein spatial distribution in normal and cancerous tissues.

21 ype and abundance of various AS events under normal and cold temperature conditions in Arabidopsis.

22 metagenomics(4-6) of placental samples from normal and complicated pregnancies.

23 eucine-rich alpha-2-glycoprotein 1 (LRG1) in normal and diabetic wound healing.

24 mouse strains with high-level engraftment of normal and diseased human immune/hematopoietic cells has

25 gain deeper insights into the PCSK6 role in normal and diseased vessel wall.

26 We investigated the normal and disrupted development of microglia in barrel

27 cription factor T-bet have been described in normal and dysregulated immune responses.

28 ells nucleate fewer astral microtubules than normal and have higher levels of Rho1-GTP at the divisio

29 h and language abilities map to the brain in normal and impaired participants, including the diverse,

30 Expression of CD163 was analyzed under normal and inflammatory conditions in mice.

31 quantify clonal expansion of hepatocytes in normal and injured liver.

32 at were subjected to intervention of saline (normal and model control group), metformin (120 mg/kg.bw

33 longin and DENN (differentially expressed in normal and neoplastic cells) domains(7), and WDR41 is a

34 allenge to interpreting enhancer function in normal and pathogenic neurobiological processes.

35 The ADC values of normal and pathological vertebrae were estimated, and th

36 Subtype 2 had normal and stable anatomy, except for larger basal gangl

37 ctome of HSP chaperone family proteins under normal and stress conditions.

38 regulation of root morphogenesis under both normal and stress conditions.

39 ls rougher) while continuously measuring the normal and tangential forces applied by the index finger

40 ted by microRNA397b (miR397b) in roots under normal and water-deficit conditions.

41 rates of tamoxifen among poor, intermediate, normal, and ultrarapid CYP2D6 metabolizers were 7.1%, 7.

42 e prevalence of tumor-related alterations in normal appearing tissues.

43 the signal difference between MS lesions and normal-appearing white matter in patients with MS.

44 ) 2.2 to 3.0 WU, considered previously to be normal, appears to associate with elevated clinical risk

45 ivatives of molecular oxygen that occur as a normal attribute of aerobic life.

46 osomal proteolysis, calcium homeostasis, and normal autophagy flux.

47 In parallel, MCL cells as compared with normal B cells expressed elevated levels of WNT16, a NF-

48 oach and demonstrated that, when compared to normal B cells, malignant plasma cells showed an extensi

49 Although the ageing OHCs retained a normal basolateral membrane protein profile, they showed

50 al days 22-28 male and female offspring from normal bedding or LB mothers.

51 use brain and showed widespread infection of normal brain cells.

52 relative signal increase of real strokes to normal brain volumes.

53 -neoplastic astrocytes, neural stem cells or normal brain.

54 n rates reached as high as 2.0E04 W/m(3) for normal breast tissue and ranged between 1.0E05-1.2E06 W/

55 On admission, physical examination was normal, but she had complained of dyspnea at the round.

56 poor in HSAN III but can be improved towards normal by application of elastic kinesiology tape across

57 hibitor deficiency (C1-INH-HAE) and HAE with normal C1-INH activity (nl-C1-INH-HAE), due to mutations

58 echanosensitive ion channels are crucial for normal cell function and facilitate physiological functi

59 timulation of T-PLL cells evoked higher-than-normal cell-cycle transition and profiles of cytokine re

60 erein, we review the regulation of 2OGDDs in normal cells and how that regulation is corrupted in can

61 otoxicity in mixed populations of cancer and normal cells.

62 contains exosomes produced by malignant and normal cells.

63 t these organelles are of key importance for normal cellular functions, a growing number of recent ob

64 he mechanisms responsible for this return to normal centriole number at the population level in human

65 bal and granule-cell-specific CB1KOs display normal cerebellum-dependent locomotor coordination and l

66 in which the border of the furcal lesion has normal characteristics; and Group C (control) in which t

67 This maintains normal charged tRNAGln levels despite Gln4p depletion, c

68 ulated based on scores for participants with normal cognition.

69 rnu ammonis regions 1 and 2 of patients with normal cognition.

70 at regulates translation and is required for normal cognition.

71 e of RA signaling is perhaps associated with normal cognitive decline with age as well as with Alzhei

72 Of the 150 participants, 21% had normal cognitive function, 17% had mild cognitive impair

73 SynGAP has emerged as a critical protein for normal cognitive function.

74 effect on their viability and function under normal conditions (both male and female mice).

75 of brain endothelial cells (ECs) under both normal conditions and after deletion of Pdcd10 (Ccm3) in

76 subpopulations of B cells express GZMB under normal conditions and which protocols effectively induce

77 three-year period (2015-2017), encompassing normal conditions, floods, a dry El Nino period, and a h

78 t on spermatogenesis or male fertility under normal conditions.

79 ss the differences in brain dynamics between normal consciousness and both drug-states.

80 act area spanning the limits of non-adhesive normal contact to adhesive contact for various substrate

81 inations, or mean deviation [MD] >-5 dB) and normal control participants.

82 with PXG compared with patients with PXS and normal control subjects (all P < .001) without a differe

83 patients with COPD compared with those from normal controls, and the levels were correlated with pul

84 205 eyes from 205 patients distributed in 82 normal corneas, 40 early-stage keratoconus and 83 establ

85 n sensitivity but also is permissive for the normal CRR to insulin-induced hypoglycemia.

86 Women with normal cytology results and positive hrHPV results were

87 ical detachment of progenitor cells from the normal delamination of daughter neuroblasts in the devel

88 o diet-induced weight gain and metabolically normal despite increased food intake, comparable activit

89 these T-ALLs and in distinct populations of normal developing thymocytes, GCs paradoxically induced

90 Dosage of imprinted genes is crucial for normal development and its dysregulation accounts for se

91 profound influence on stem cell fate during normal development in maintenance of physiologic tissue

92 of integrin beta1 in the liver disrupts the normal development of hepatocyte polarity, specification

93 rin ligands control cell interactions during normal development, and reemerge in tumors and the TME,

94 hymal cell crawling is a critical process in normal development, in tissue function, and in many dise

95 Thus, while infra-normal deviations were common among patients, their anat

96 Normal diastolic function was found in 23 (11%) patients

97 expression in the lung tissue compared with normal diet (ND)-fed mice.

98 per microliter [4.5-11 cells x 10(9)/L]), a normal differential leukocyte count (74% neutrophils [no

99 For normal diffusion, the fluorescence recovery produced a s

100 There is a normal distribution across the population in how the cir

101 eterogeneity is often invoked to explain non-normal distributions of greenhouse gas (GHG) fluxes, als

102 of peptide YY to EEC-deficient mice restores normal electrophysiology, improves glucose and peptide a

103 VPS4A function was also required for normal endosomal morphology and IST1 localization in iPS

104 Constitutively, compared with normal endothelial (Endo-N) cells, Endo-T cells differen

105 ct of oncogene activation on this process in normal epithelial cells.

106 ecific to either prostate cancer or prostate normal epithelium.

107 Energy balance and eating behavior were also normal, even after exposure to high-fat diet.

108 ebellar granule-cell-specific CB1KOs exhibit normal eyeblink conditioning, and both global and granul

109 operator with Pentacam HR in keratoconus and normal eyes.

110 What is a normal face?

111 cardiomyocytes (CMs) and non-CMs (NCMs)-from normal, failed and partially recovered (left ventricular

112 atable glaucomatous SAP defects vs eyes with normal fields.

113 ed the plate as contaminated or growing only normal flora and not due to threshold counts.

114 <35 mL/m(2) (low flow, LF) or >=35 mL/m(2) (normal flow, NF).

115 CLF-LG; (3) paradoxical low-flow-LG; and (4) normal-flow-LG.

116 e Pten((fl/fl)) Kras(G12V/+) (G12V mice) had normal follicle structures, and about 90% of them develo

117 CSF glucose and protein levels were normal for 83/116 (75.2%) and 51/116 (44%) positive spec

118 the autophagy machinery is necessary for the normal formation and compartmentalization of protein agg

119 acute leukemias, lamin A/C helps distinguish normal from neoplastic mature T cells, and VAMP-7 recapi

120 Our results offer new insight into the normal function of PC2 as a ubiquitous stress-sensitive

121 of full-length (FL) transcripts required for normal function remains to be established.

122 ic shapes and positions that are crucial for normal function.

123 xhibits strong circadian rhythms to maintain normal functioning.

124 tant has an unusual mechanism as it depletes normal-functioning DNM2 from autophagosome formation sit

125 ther related degenerative disorders, and the normal functions of Vn, especially those related to bone

126 set the defect in insulin action to maintain normal glucose tolerance.

127 ts included 256 with diabetes and 133 with a normal glucose tolerance.

128 ll function, tmc triple-mutant larvae retain normal gross morphology of hair bundles and proper traff

129 Hydrolysis of c-di-AMP is critical for normal growth and differentiation in Streptomyces, conne

130 llectively, we propose that EXOSC10 promotes normal growth-to-maturation transition in mouse oocytes

131 other key stereociliary proteins involved in normal hair bundle morphogenesis, such as CDC42, RAC1, E

132 r, these data suggest that LGR4 promotes the normal hair cycle by activating HF stem cells and by inf

133 onmental challenges is paramount to maintain normal health, and individuals lacking or unable to make

134 The majority of infants with cCMVi have normal hearing at birth, but are at risk of developing l

135 potential, thereby playing a pivotal role in normal hearing.

136 noise or competing talkers, despite having "normal" hearing in terms of audiometric thresholds.

137 r hearing-impaired listeners and age-matched normal-hearing controls.

138 g heart is more prone to sustain VF than the normal heart, and is at least as susceptible to sustaine

139 nd a molecular mechanism whereby AML impairs normal hematopoiesis by remodeling the mesenchymal niche

140 m cell (LSC) function but is dispensable for normal hematopoiesis.

141 an important role of DNA methylation in the normal homeostasis of cardiomyocytes and during cardiac

142 of compounds in a panel of primary ADPKD and normal human kidney (NHK) epithelial cells.

143 form of the protein, however, has a role in normal human macrophage function has not been determined

144 tion of cell metabolic pathways that underly normal human T cell responses have taught us that there

145 g cancer driver mutations, in histologically normal human tissues suggest that mutations alone are no

146 ies have started to map somatic mutations in normal human tissues, and here we discuss their implicat

147 tein levels from over 12,000 genes across 32 normal human tissues.

148 64 chest radiographs were obtained, of which normal images accounted for 98.0% (1925 of 1964 radiogra

149 Understanding the processes underlying normal, impaired, and recovered language performance has

150 ich synapse counts recover from 16 to 91% of normal in the most affected regions.

151 the fact that this region loses most of its normal input after such an injury, and is clearly a majo

152 ce of BRCA1-bound RAP80 are critical for the normal interaction of BRCA1 with some of its partners (e

153 retain an expression profile consistent with normal intestinal function but also show distinct molecu

154 ibit pathologic angiogenesis but also extend normal intraretinal angiogenesis by ordering the develop

155 All normal IOL formulas resulted in hyperopic refractive out

156 Thus, LOXL1 expression is required for normal IOP control, while ablation results in altered EC

157 e retinal blood flow in POAG patients with a normal IOP.

158 has an identical twin sister who maintained normal iris pigmentation during the entire course.

159 current decreased with age, IHCs retained a normal KCNQ4 current and resting membrane potential.

160 ormation about Gdf15 activity and effects in normal kidney and in AKI.

161 ia (P = 0.007) and, in the tertile with both normal kidney function (eGFR 84 +/- 11.7 ml/min/1.73m(2)

162 lar and pulmonary arterial pressures, toward normal levels of right-side pressure (about 20 mmHg) mea

163 t and Flt3 ligand restores cDC1 abundance to normal levels, decreases cDC1 apoptosis, and repairs cDC

164 r formation, and reduces TRPM7 expression to normal levels.

165 ponse, decreasing excess spermidine pools to normal levels.

166 n B cells using CD19-Cre, female mice have a normal life span without obvious illness.

167 potential benefits of statin use in PWH with normal lipid levels requires further clinical outcome re

168 Liver fibrosis interferes with normal liver function and facilitates hepatocellular car

169 Purpose To determine normal liver stiffness, and associated normal ranges for

170 m patients with AH or alcoholic cirrhosis or normal liver tissue from hepatic resection.

171 to define obstructive sleep apnea severity (normal, <5.0; mild, 5.0-14.9; moderate, 15.0-29.9; and s

172 ell-specific enhancers that differed between normal luminal and basal mammary cells.

173 Prominent uptake was seen in multiple normal lymph nodes as early as 2 h after injection, peak

174 accumulation at the cortical cytoskeleton in normal mammary epithelial cells.

175 itative assessment reveals variability and a normal mean rate of age-related decline, consistent with

176 ting PRDM9-dependent histone methylation and normal meiotic progress, possibly by facilitating the li

177 nhibited melanoma cell proliferation but not normal melanocytes.

178 The hippocampus is essential for normal memory but does not act in isolation.

179 of cytokine release that resembled those of normal memory T cells.

180 d is attributed to a phase transition from a normal metal to a spin-polarized correlated state.

181 induction of lipid cacostasis in the CNS of normal mice was associated with ALS-like lipid pathology

182 tion of the underlying epithelia by both the normal microbiota and enteric pathogens.

183 is rescued after cell transplantation into a normal microenvironment, thus proving the active role of

184 Normal mode and molecular dynamics analyses indicate tha

185 ckdown during which 25%, 50%, and 75% of the normal monthly volumes of symptomatic patients delayed t

186 sing the culture media of human embryos with normal morphologic features, we found that the concentra

187 in generated chimeric filaments of seemingly normal morphology but with occasional prominent irregula

188 Brain dopamine is critical for normal motor control, as evidenced by its importance in

189 Individuals with temporal lobe epilepsy and normal MRI showed a similar pattern of greater ipsilater

190 cascade is tightly regulated and central to normal neuronal development and survival.

191 ncreased synaptic vesicle numbers, restoring normal neurotransmission.

192 orrected protein glycosylation (2 of 2), and normal neutrophil chemotaxis (1 of 1), and bactericidal

193 Conversely, normal numbers of PML NBs were restored upon transition

194 nteractions were not detected in cognitively normal older adults with "neurotypical" levels of amyloi

195 ative cell type of mesenchymal HNSCC and its normal oral keratinocyte counterpart.

196 inal attachment, and interactions needed for normal outer segment phagocytosis.

197 r demonstrated improved neutrophil function: normal oxidative burst (in 3 of 3 patients tested), corr

198 entrations ranged from 332 to 9520 ppm under normal P and from 83 to 8473 ppm under reduced P conditi

199 TCGA database, paired PDA and adjacent normal pancreatic tissues, PDA tissue array and cell lin

200 e eye each of 39 glaucoma and 31 age-matched normal participants was scanned using 4.5-mm OCTA scans

201 Also, in a comparison made between normal patients and patients with dissection, right CCA

202 ients, while showing no cytotoxicity against normal PBMCs, NIH3T3, and HEK293 cells.

203 sion mismatching in the noninjured lung, and normal perfusion of the relatively small fraction of inj

204 ing ciliary structure and function towards a normal phenotype.

205 e(+)) were completely free of tumors and had normal phospho-ERK activity compared with Nf1(flox/flox)

206 e-wide changes in gene expression during the normal physiological fasting-feeding cycle in nutrient-s

207 ncepts are placed within the context of both normal physiology and the pathophysiology of disease and

208 ata shed light on the function of C9orf72 in normal physiology, and in amyotrophic lateral sclerosis

209 erest because of genetic variation affecting normal pigmentation variation in humans.

210 ively unstable in placental homogenates from normal placentas.

211 ndoreplication plays important roles in both normal plant development and in stress responses.

212 activated FIX in buffer and initiated TG in normal pooled plasma, as well as FXII- or FXI-deficient

213 adhesions, whereas vinculin remained in its normal position within the force transduction layer.

214 re6P) and is essential for embryogenesis and normal postembryonic growth and development.

215 Only rabbits with cell-seeded constructs had normal pregnancies (four in ten) in the reconstructed se

216 women with SCH when compared to women with a normal pregnancy, in the second trimester.

217 rcinoma initiation, but does not perturb the normal pregnancy-induced epigenomic landscape.

218 ely 10% of dementia patients have idiopathic normal pressure hydrocephalus (iNPH), an expansion of th

219 ke growth factor-1) is markedly decreased in normal preterm infants, but whether IGF-1 treatment can

220 Normal prostatic epithelium employs comparatively glycol

221 Therefore, normal protein diet is indispensable for maternal muscul

222 (BiPs) are molecular chaperones involved in normal protein maturation and refolding malformed protei

223 ICG-PEG45 to be effectively effluxed out of normal proximal tubules through P-glycoprotein transport

224 phisms alter function varies from conserving normal pyroptotic function to inhibiting caspase cleavag

225 seline serum tryptase level within the upper normal range (8-11.5 ng/mL) was more frequently associat

226 concentrations were also elevated above the normal range in 16 (80%) of 20 non-ICU patients.

227 and ATXN2 CAG repeat expansions in the long normal range increase ALS risk.

228 protein level of 203.8 mg/L (1940.9 nmol/L) (normal range, <=10 mg/L [<=95.2 nmol/L]).

229 protein level of 203.8 mg/L (1940.9 nmol/L) (normal range, <=10 mg/L [<=95.2 nmol/L]).

230 rocyte sedimentation rate of 31 mm per hour (normal range, 0-29 mm per hour).

231 vated sedimentation rate of 100 mm per hour (normal range, 0-30 mm per hour), and a C-reactive protei

232 vated sedimentation rate of 100 mm per hour (normal range, 0-30 mm per hour), and a C-reactive protei

233 [normal range, 20%-40%], and 2% eosinophils [normal range, 1%-4%]), and an erythrocyte sedimentation

234 owed mild anemia (hemoglobin level, 10 g/dL; normal range, 12-15 g/dL), a total leukocyte count of 14

235 ls [normal range, 40%-80%], 24% lymphocytes [normal range, 20%-40%], and 2% eosinophils [normal range

236 l count of 15.1 x 10(3)/uL (15.1 x 10(9)/L) (normal range, 4.0-10.0 x 10(3)/uL [4.0-10.0 x 10(9)/L]),

237 cell count of 15.1 x 103/muL (15.1 x 109/L) (normal range, 4.0-10.0 x 103/muL [4.0-10.0 x 109/L]), an

238 fferential leukocyte count (74% neutrophils [normal range, 40%-80%], 24% lymphocytes [normal range, 2

239 0 cells per microliter (14 cells x 10(9)/L) (normal range, 4500-11 000 cells per microliter [4.5-11 c

240 nd endothelial cell count values were in the normal range.

241 ange, cell stress remains low and within the normal range.

242 rmine normal liver stiffness, and associated normal ranges for children, as measured with MR elastogr

243 n of a few well-known disease-relevant STRs, normal ranges of repeat counts for most STRs in human po

244 els reported to induce SCZ-like phenotype in normal rat strains, increased NDEL1 enzyme activity in b

245 t of a predicted upstream regulator disrupts normal regeneration, validating our prediction.

246 , which has important roles including aiding normal replication rates and stabilizing stalled forks.

247 In normal resting B cells, IFITM3 was minimally expressed a

248 GRK1-S21A mice had normal retinal morphology, without evidence of degenerat

249 expression will not produce an excess of the normal RPE65 protein level.

250 However, PCNA is also ubiquitinated during normal S-phase progression.

251 0 mg dose of ferric carboxymaltose in 100 mL normal saline, and placebo was 100 mL normal saline, bot

252 100 mL normal saline, and placebo was 100 mL normal saline, both given as an infusion over 15 min.

253 epC, can effectively distinguish tumors from normal samples with an accuracy of 90% for Pan-Cancer an

254 abenzosapphyrin did not show ring inversion (normal sapphyrins).

255 ll secretion site, which are required during normal shell growth, and repair.

256 n-hyaluronan are constitutively expressed in normal skin and increase post-wounding but are completel

257 ecord BG spiking and field potentials during normal sleep and in 1-methyl-4-phenyl-1,2,3,6-tetrahydro

258 upstream of serotonin in the RN to maintain normal sleep levels.

259 emonstrated that FLM can be used to describe normal sleep-wake cycles of healthy adult dogs and the e

260 y shorter after sleep deprivation than after normal sleep: (30 min [interquartile range [IQR], 17-41]

261 define SIBO is our limited understanding of normal small intestinal microbial populations-progress i

262 nce of dominant and subordinate males during normal social interactions and in a more complex group c

263 of whispered sounds, and in congruence with normal speech articulation, as accounted for by the Baye

264 +/- categories according to the abnormal (+)/normal (-) status of Abeta ((18)F-florbetapir or (18)F-f

265 n after ajmaline (ajmaline-negative); (4) 47 normal subjects; (5) 18 patients with right bundle branc

266 In a normal surveillance state, microglia use oxidative phosp

267 during the synaptic vesicle cycle to ensure normal synaptic transmission.

268 to identify the relationship between them in normal Thai eyes.

269 diatric brain tumors by reducing the dose to normal tissue compared with that of photon radiotherapy

270 mmation for tissue repair and restoration of normal tissue homeostasis once an infection is controlle

271 and cross-talk between autophagy and Lkb1 in normal tissue homeostasis, we generated genetically engi

272 The high tumour-to-normal tissue ratio offered by TMRET in combination with

273 Developmental processes underlying normal tissue regeneration have been implicated in cance

274 cing was performed on 62 HGT1 and 15 matched normal tissue samples.

275 esenting a range of prostate phenotypes from normal tissue to drug-resistant metastases.

276 rom three large datasets consisting of adult normal tissue, adult cancer tissue, and pediatric cancer

277 ome, studying 1526 tumors and their adjacent normal tissues across seven cancer types, including brea

278 on most cancer yet rarely detected in adult normal tissues as reported in previous studies, featurin

279 trolling immune recognition and responses in normal tissues as well as the tumor microenvironment.

280 cesses that underpin mutational selection in normal tissues remain poorly understood.

281 sues can only be distinguished from adjacent normal tissues using quantitative results of both lipid

282 y restricted to the endoplasmic reticulum in normal tissues, but which is expressed on the cell surfa

283 EBV nuclear proteins usurp normal transcriptional programs to activate the expressi

284 ignificant fraction of both the aberrant and normal transcriptomes.

285 onal methods that are primarily designed for normal-tumor matched data and can be confounded by genom

286 ring subsequent to this hyperpolarization in normal type II UBCs.

287 some geographic variations in healthcare are normal, unwarranted variations raise questions about the

288 tion in intraperitoneal pressure (IPP), from normal values of 5 mmHg to as high as 22 mmHg, causes st

289 f diaphragmatic motion velocity, measure its normal values, and determine the intra- and interobserve

290 cannot suppress VEGFA expression to support normal vascular development.

291 ockers are reasonable drugs in patients with normal ventricular systolic function.

292 Normal versus pathological aggregation may be distinguis

293 mers of VWF, multimeric recombinant VWF, and normal VWF plasma concentrates.

294 parameters < 296 dB/m, BMI < 25 kg/m(2) and normal waist circumference were included in the interven

295 sity lung volume compared to patients on the normal ward, but a significantly larger volume of high-d

296 or having keratoconus were compared with the normal weight group.

297 Obese and normal weight patients did not differ in relation to the

298 Among normal weight women category, compared with adequate GWG

299 with T2D (15.8% versus 5.7% obese versus 0% normal weight).

300 s of obese patients compared with those of a normal weight.