ライフサイエンスコーパス: normothermic

1 plantation) and temperatures (hypo-, sub, or normothermic).

2 or 48 hrs and then were rewarmed or remained normothermic.

3 likely to develop an SSI than those who were normothermic.

4 imb was then attached to a custom-made, near-normothermic (30-33 degrees C) ex situ perfusion system

5 phorylated at 5 and 24 h after stroke in the normothermic (37 degrees C) brain; hypothermia augmented

6 rees C with 1 hour of circulatory arrest) or normothermic (37 degrees C) CPB for 2 hours.

7 olution during a 30-minute period of global, normothermic (37 degrees C) ischemia followed by 30 minu

8 on underwent ex situ viability testing using normothermic (37 degrees C) machine perfusion (NMP) afte

9 Thereafter, kidneys were reperfused with normothermic (37 degrees C) oxygenated blood for 4 hours

10 After normothermic (37 degreesC) ischaemia/reperfusion, signif

11 d to either hypothermic (32-34 degrees C) or normothermic (37-39 degrees C) conditions, and received

12 (over 400 recorded hours) were normal in all normothermic and hyperthermic control rats, and none of

13 Conversely, a minority of normothermic and hyperthermic controls had (brief) seizu

14 normal and elevated pressures and under both normothermic and hypothermic conditions.

15 aseline cerebral blood flow is similar after normothermic and hypothermic CPB, beta-adrenergic respon

16 ma patients and is a durable measure in both normothermic and hypothermic patient groups.

17 rease and increase CVC, respectively, during normothermic and whole-body heating conditions in restin

18 minute periods of data were examined during normothermic and whole-body heating conditions.

19 In normothermic animals and to a greater degree in hyperthe

20 Ten of 12 normothermic animals failed to survive the reperfusion p

21 Normothermic animals were maintained at 37 +/- 0.2 degre

22 Normothermic animals were maintained at 37+/-0.2 degrees

23 kt activity measured in an in vitro assay in normothermic animals.

24 d decreased blood flow were observed only in normothermic animals.

25 ardiac arrest characterized by 12 minutes of normothermic asystole and a high cardiopulmonary resusci

26 Patients receiving normothermic blood had less postoperative right ventricu

27 ediately upon reperfusion and 1 h later; all normothermic brains showed space immunoreactivity at 4 h

28 At the end of normothermic bypass diameter of cerebrocortical microves

29 parietal cerebral cortex underwent 10-minute normothermic bypass, 40-minute cooling on cardiopulmonar

30 HODS AND Mice were subjected to 8 minutes of normothermic CA and resuscitated with chest compression

31 ing (CABG) (n = 6; low SOE), hypothermic and normothermic CABG (n = 3; moderate to low SOE), or CABG

32 y-cerebral resuscitation following 9 mins of normothermic cardiac arrest in male vs. female dogs.

33 brain, heart, and organism (within 5 mins of normothermic cardiac arrest no-flow), which increases th

34 After normothermic cardiac arrest of 11 mins in dogs, mild res

35 to complete recovery after 10 to 15 mins of normothermic cardiac arrest without blood flow.

36 angendorff-perfused and exposed to 40-minute normothermic, cardioplegic global ischemia and 30 minute

37 ocrit supporting cerebral oxygenation during normothermic cardiopulmonary bypass (CPB) in dogs.

38 Previous studies have found that normothermic cardiopulmonary bypass (CPB) is associated

39 When epinephrine was administered during normothermic cardiopulmonary resuscitation, postresuscit

40 Epinephrine, when administered during normothermic cardiopulmonary resuscitation, significantl

41 the lungs with preservation of the abdominal normothermic circulation throughout the thoracic procure

42 esected lobes were perfused in acellular and normothermic condition.

43 Under normothermic conditions (34 degrees C) and at 39 degrees

44 igher during passive leg heating compared to normothermic conditions (FVC at highest dose of respecti

45 reases in FVC during leg heating compared to normothermic conditions (maximal decreases in FVC during

46 ypothermic animals (n = 12) were returned to normothermic conditions 120 minutes after clamp removal.

47 m 0 to 1000 mug/mL under subnormothermic and normothermic conditions in PS.

48 he hypothermic animals that were returned to normothermic conditions survived.

49 ctions of the intact pig brain under ex vivo normothermic conditions up to four hours post-mortem.

50 Under halothane anesthesia and normothermic conditions, 72 DNX inbred mice were subject

51 h the addition of oxygen carriers; and under normothermic conditions.

52 R is unclear, especially after the return to normothermic conditions.

53 dose of respective drugs during heating vs. normothermic conditions: PE: 3.7 +/- 0.4 vs. 2.0 +/- 0.3

54 ics, PS sustained bacterial growth under sub(normothermic) conditions, whereas growth was absent in c

55 gia for 5 minutes, followed by 60 minutes of normothermic continuous cardioplegic administration with

56 dioplegic arrest and rewarming compared with normothermic control (37 +/- 3 vs 69 +/- 3 microns/s, P

57 nd prolonged external cooling (21+/-14%) vs. normothermic control (61+/-32%) and brief external cooli

58 prolonged external cooling (18+/-9 secs) vs. normothermic control (74+/-17 secs) and brief external c

59 nd prolonged external cooling (score, 0) vs. normothermic control (score, 20) and brief external cool

60 Except for three normothermic control animals, all animals were resuscita

61 A historic normothermic control group was matched (one-to-one) by m

62 ere cooled to 30 degrees C for 1 hour; and a normothermic control group, in which mice were kept at 3

63 was severely impaired when compared with the normothermic control group.

64 myocyte velocity of shortening compared with normothermic control values (33+/-2 versus 66+/-2 microm

65 assigned to the following treatment groups: normothermic control, incubation in cell culture media f

66 Rats were randomized to a normothermic control, neurotensin-induced hypothermia, b

67 ytes were randomly assigned to 3 groups: (1) normothermic control: 37 degrees C x 2 hours (n = 116);

68 of spontaneous circulation compared to 9% in normothermic controls (*p < .01 vs. normothermia).

69 %*, and 0%, respectively, compared to 2% for normothermic controls (*p < .05 vs. normothermia).

70 te myocyte shortening velocity compared with normothermic controls (22.0 +/- 1.6 versus 57.2 +/- 2.6

71 , and 14%, respectively, compared to 17% for normothermic controls and survival with good neurologic

72 fluid and in homogenized lungs compared with normothermic controls but was associated with reduced ba

73 in rats treated with hypothermia compared to normothermic controls in both injury groups (P < 0.05).

74 Five animals served as normothermic controls.

75 spinal neurons (127% increase) compared with normothermic controls.

76 ted (hyperthermic controls), as well as with normothermic controls.

77 m uninstrumented controls (91+/-2%) or after normothermic CPB (84+/-4%).

78 79 men, mean age 63 (40 to 77) years)] with normothermic CPB and cardioplegic arrest of the heart or

79 Pigs (n = 6) were placed on normothermic CPB and hearts were arrested for 1 hour wit

80 Pigs were subjected to normothermic CPB for 90 minutes, followed by post-CPB pe

81 -dependent) was between 0.09 and 0.14 during normothermic CPB in dogs.

82 d by 8-bromo-cAMP was markedly reduced after normothermic CPB, and this change was directly related t

83 s are unchanged in the skeletal muscle after normothermic CPB.

84 A desensitizes alpha-adrenoceptors more than normothermic CPB.

85 arterial blood pressure (MAP) on CBF during normothermic CPB.

86 16) of change in MAP on change in CBF during normothermic CPB.

87 While normothermic, CVP was 6.3 +/- 0.2 mmHg and PCWP was 9.5

88 roup I and group II patients were maintained normothermic during OLT); and group III (n=5), had uncon

89 Seven subjects underwent 30 mmHg LBNP while normothermic, during passive heat stress (increased inte

90 negative pressure (LBNP) while subjects are normothermic, during skin-surface cooling, and during wh

91 f four groups: normothermic placebo control; normothermic epinephrine; hypothermic placebo control; a

92 C flush; target temperature, 15 degrees C); normothermic EPR (N-EPR; 38 degrees C flush); and contro

93 r lung reconditioning in a model of extended normothermic EVLP.

94 A program of normothermic ex situ liver perfusion (NESLiP) was develo

95 Normothermic ex situ liver perfusion (NEsLP) offers the

96 Normothermic ex situ liver perfusion enabled assessment

97 Normothermic ex situ liver perfusion has the potential t

98 Normothermic ex situ liver perfusion was performed using

99 rafts appeared viable after 24 hours of near-normothermic ex situ perfusion.

100 Recent developments in the field of normothermic ex vivo cardiac perfusion storage have now

101 ith a novel technique of pressure-controlled normothermic ex vivo kidney perfusion (NEVKP) in heart-b

102 We compared continuous normothermic ex vivo kidney perfusion (NEVKP) with hypot

103 We compared continuous pressure-controlled normothermic ex vivo kidney perfusion (NEVKP) with stati

104 Normothermic ex vivo kidney perfusion might help to decr

105 SCS), however, it is currently unknown after normothermic ex vivo liver perfusion (NEVLP).

106 Normothermic extracorporeal liver perfusion (NELP) has b

107 animals were resuscitated and submitted to a normothermic follow-up (control group) or to 3 hours of

108 rats were subjected to either 7 or 8 min of normothermic forebrain ischemia (bilateral carotid occlu

109 ental hearts were subjected to 30 minutes of normothermic global ischemia followed by 2 hours of repe

110 The hearts were then subjected to 20 min of normothermic global ischemia followed by 25 min of reper

111 minutes before being subjected to zero-flow normothermic global ischemia for 35 minutes and reperfus

112 mic group (35.4+/-0.1 degrees C) than in the normothermic group (36.7+/-0.1 degrees C) (P<.001) and r

113 posite Score versus 20.0% of patients in the normothermic group (p = 0.317).

114 test, compared with 55.5% of patients in the normothermic group (p = 0.865).

115 mic episode, glutamate concentrations in the normothermic group peaked at levels approximately three

116 rdiac events occurred less frequently in the normothermic group than in the hypothermic group (1.4% v

117 ycardia also occurred less frequently in the normothermic group than in the hypothermic group (2.4% v

118 r in the hypothermia group compared with the normothermic group.

119 bral organ damage were assessed at 96 hrs.In normothermic groups 1 and 4, all 12 dogs achieved sponta

120 Myocardial damage scores were worse in the normothermic groups compared with both hypothermic group

121 te Examination scores in the hypothermic and normothermic groups were 27.4 +/- 3.8 and 26.8 +/- 4.5,

122 idence of impairment between hypothermic and normothermic groups.

123 unused human kidneys in a series of ex-vivo normothermic haemo-reperfusion models.

124 unused human kidneys in a series of ex vivo normothermic hemoreperfusion models.

125 a nonhibernating mammal and that recovery of normothermic homeostasis ensues upon rewarming.

126 an 'area' control site has been described in normothermic humans.

127 ls were randomized into 4 groups (n=6 each): normothermic, hypothermic-2 hours, hypothermic-5 hours,

128 Langendorff method and subjected to global, normothermic I/R (20/40 minutes), with or without prior

129 tected the human donor proximal tubules from normothermic-induced cell swelling.

130 After normothermic infusions of dopamine at different doses (4

131 liver for 1 hour after a 15-minute period of normothermic intestinal ischemia.

132 el, 45 hearts underwent 30 minutes of global normothermic ischemia after infusion of 50 mL of cardiop

133 been shown to confer protection in models of normothermic ischemia and reperfusion injury and to init

134 icant sparing of CA1 neurons relative to the normothermic ischemia group was observed.

135 lmonary bypass, a 45-minute period of global normothermic ischemia was followed by 60 minutes of inte

136 d mechanism of effect have been primarily of normothermic ischemia where adenosine was given pre-isch

137 abbit hearts were subjected to 45 minutes of normothermic ischemia with cardioplegic arrest.

138 After global normothermic ischemia, significant decreases in cardiac

139 shown to enhance myocardial tolerance after normothermic ischemia-reperfusion.

140 istar rats were subjected to 30 or 60 min of normothermic ischemia.

141 groups before and after a 6-minute period of normothermic ischemia.

142 erformance deficits relative to shams in the normothermic ischemic group, with the postischemic hypot

143 hypothermic), after rewarming (hypotensive, normothermic) just before discontinuation of cardiopulmo

144 ASO when applied in normothermic kidney machine perfusion reduced renal miR-

145 urement of urinary biomarkers during ex vivo normothermic kidney perfusion (EVKP) may aid in the asse

146 Transportable normothermic kidney perfusion for 24 hours or longer cou

147 We conclude that ex vivo normothermic kidney perfusion with a plasma-free red cel

148 While normothermic,LBNP reduced blood volume in all regions (t

149 stress + clamp successfully restored to the normothermic level (P = 0.99) and increased MCA V(mean)

150 ive heat stress with P(ETCO2) clamped at the normothermic level (using a computer-controlled sequenti

151 uent volume loading returned those values to normothermic levels.

152 pidly (n = 6) or slowly (n = 5) increased to normothermic levels.

153 ontaneous circulation, they underwent either normothermic life support (control group, n = 12) or hyp

154 sion, rabbits underwent either oxygen (Gas), normothermic liquid (Liquid Warm), or cold liquid (Liqui

155 function in rat donor livers during ex situ normothermic machine perfusion (NMP) and after orthotopi

156 y was to evaluate sequential hypothermic and normothermic machine perfusion (NMP) as a tool to resusc

157 Normothermic machine perfusion (NMP) bears the potential

158 Ex situ normothermic machine perfusion (NMP) can be performed af

159 Ex situ normothermic machine perfusion (NMP) can be used to asse

160 sent the first patients transplanted using a normothermic machine perfusion (NMP) device that transpo

161 Normothermic machine perfusion (NMP) enables optimized e

162 Normothermic machine perfusion (NMP) has been used to re

163 To this end, normothermic machine perfusion (NMP) has emerged as a pl

164 Normothermic regional perfusion (NRP) and normothermic machine perfusion (NMP) have both been used

165 Normothermic machine perfusion (NMP) is an emerging moda

166 Ex situ normothermic machine perfusion (NMP) is being used incre

167 xperimentation, outcomes of a first clinical normothermic machine perfusion (NMP) liver trial in the

168 Ex vivo normothermic machine perfusion (NMP) of donor kidneys pr

169 Normothermic machine perfusion (NMP) of liver grafts is

170 Normothermic machine perfusion (NMP) technologies are em

171 ials.gov number NCT02740608) outcomes, using normothermic machine perfusion (NMP) to objectively asse

172 Normothermic machine perfusion (NMP), a method of organ

173 Normothermic machine perfusion of human kidneys for 24 h

174 les, potentially administered during ex vivo normothermic machine perfusion of human organs, could be

175 Normothermic machine perfusion of the liver (NMP-L) is a

176 ted livers following viability assessment by normothermic machine perfusion of the liver (NMP-L).

177 xt, kidneys were reperfused for 4 hours in a normothermic machine perfusion setup.

178 tatic cold storage, the liver was subject to normothermic machine perfusion with a plasma-free red ce

179 rts failed to meet viability criteria during normothermic machine perfusion, and 2 hearts were declin

180 fferences between normothermically perfused (normothermic machine perfusion, NMP) human kidneys with

181 to controls or after a subsequent 3 hours of normothermic machine perfusion.

182 significantly better kidney function during normothermic machine perfusion.

183 d, preserved, and implanted under continuous normothermic machine perfusion.

184 ro (approximately 0.2 Hz) and in most intact normothermic mammals.

185 Following normothermic MCA occlusion, spectrin immunoreactivity wa

186 Nasralla et al demonstrating the efficacy of normothermic MP over static cold storage, MP is likely h

187 hermic, fast resolvers" (n = 2,877; 23.2%); "normothermic" (n = 4,067; 32.8%); and "hypothermic" (n =

188 ic, fast resolvers" (n = 18 C1; n = 24 C2), "normothermic" (n = 54 C1; n = 31 C2), and "hypothermic"

189 ed from 5 to >10 mins the previously longest normothermic no-flow time that could be reversed to comp

190 nesthetized, instrumented, and randomized to normothermic (Nor) or hypothermic (Hy) conditions.

191 is study included five treatment groups: (1) normothermic (Normo)-brain temperature was maintained at

192 tress were appropriate to maintain CDO(2) at normothermic, normoxic values.

193 ns of similar complexities in a hot and in a normothermic operating room.

194 e of the liver to ischemia-reperfusion under normothermic or hypothermic conditions.

195 re not modulated by arterial baroreflexes in normothermic or moderately heated individuals.

196 artery (MCA) occlusion and were either kept normothermic or rendered mildly hypothermic shortly afte

197 grees C throughout ischemia and reperfusion (Normothermic), or given 1 h of hypothermic conditions (2

198 se cefazolin be used for prophylaxis in (sub)normothermic organ preservation with PS.

199 Hypothermic and normothermic oxygenated machine perfusion (NMP) were per

200 A customized ex vivo normothermic oxygenated perfusion (NP) system with added

201 olated working rat hearts were arrested with normothermic oxygenated potassium cardioplegia for 5 min

202 Intubated, anesthetized rats underwent normothermic parasagittal fluid-percussion brain injury

203 wer admission Glasgow Coma Scale scores than normothermic patients (p = .04) and tended to have highe

204 ermic patients were 3 times more likely than normothermic patients to develop MODS (21% vs. 9%, P = 0

205 try were performed every 6 hrs for 24 hrs in normothermic patients who were at rest for at least 30 m

206 nation for mortality in both hypothermic and normothermic patients.

207 were increased over time in hypothermic vs. normothermic patients.

208 ion, the 55-year-old female recipient of the normothermic perfused kidney had slow graft function but

209 A short period of ex vivo normothermic perfusion (EVNP) immediately before transpl

210 The role of ex vivo normothermic perfusion (EVNP) in both organ viability as

211 Ex vivo normothermic perfusion (EVNP) is a novel method of prese

212 Ex vivo normothermic perfusion (EVNP) may be useful as a means t

213 Ex vivo normothermic perfusion (EVNP) prior to transplantation m

214 after perfusion and assessment using ex vivo normothermic perfusion (EVNP).

215 aastricht category III donors with abdominal normothermic perfusion and concomitant cold lung flushin

216 of leukocyte filters recovered from ex vivo normothermic perfusion circuits of human kidneys retriev

217 In all cases, normothermic perfusion either maintained or slightly imp

218 Normothermic perfusion failed to resuscitate porcine liv

219 After normothermic perfusion for 15 minutes and separation fro

220 WI group) were placed in an EVLP circuit for normothermic perfusion for 3 hours.

221 also reviews pulsatile machine perfusion and normothermic perfusion for pancreas preservation techniq

222 Normothermic perfusion has been shown to resuscitate and

223 Normothermic perfusion is an alternative but little stud

224 The combined use of ex vivo hypothermic and normothermic perfusion may be a useful strategy to more

225 The authors report a case of preimplant normothermic perfusion of a suboptimal liver from a 57-y

226 We report ex vivo normothermic perfusion of human pancreases procured but

227 Normothermic perfusion of liver grafts before transplant

228 Preimplant ex situ normothermic perfusion of the liver appears to be a prom

229 ine recirculation (n = 3) achieved a reduced normothermic perfusion time of 7.7 +/- 1.5 hours and sig

230 Normothermic perfusion was continued for 2 hr before in

231 After 132 minutes, normothermic perfusion was stopped and implantation begu

232 x vivo viability assessment using postmortem normothermic perfusion, and overall macroscopic appraisa

233 ipient outcomes were documented after 4 h of normothermic perfusion.

234 rfusion (26 degrees C) interspersed by 3 min normothermic perfusion.

235 alternative preservation techniques, such as normothermic perfusion.

236 Normothermic, physiologically regulated male Sprague-Daw

237 it of autoregulation compared to postarrest, normothermic piglets.

238 hen randomly assigned to one of four groups: normothermic placebo control; normothermic epinephrine;

239 EXPAND trial was to evaluate the efficacy of normothermic portable Organ Care System (OCS) Lung perfu

240 he effective antibiotic prophylaxis for (sub)normothermic preservation by investigating whether Staph

241 f Wisconsin solution for 4 hours followed by normothermic preservation for 20 hours (total preservati

242 gned to the following groups: group W (n=5), normothermic preservation for 24 hours; and group C (n=4

243 f short duration of cold preservation before normothermic preservation on the function of porcine NHB

244 postischemic hypothermia (30 degrees C); (c) normothermic procedures combined with delayed injections

245 To establish the role of P-selectin in normothermic pulmonary ischemia, mice were subjected to

246 In normothermic pups, Fos immunoreactivity peaked at early

247 ntusion volume was larger in hypothermic vs. normothermic rats (44.3 +/- 4.2 vs. 28.6 +/- 4.0 mm, p <

248 Conscious normothermic rats (n=12 per group) were also given RSR13

249 e (MK-801) was then constructed in conscious normothermic rats subjected to 75 min of MCAO.

250 Groups 1, 3 and 5 consisted of normothermic rats that underwent either 6 (for CBF measu

251 Corresponding to GSK 3beta activity in normothermic rats, beta-catenin phosphorylation transien

252 - and pCREB-immunoreactive cells compared to normothermic rats.

253 obal brain ischemia (12.5 min) in ventilated normothermic rats.

254 ced contusion volumes, compared with hypoxic normothermic rats.

255 fect on body temperature when given alone to normothermic rats.

256 opil and only selective neuronal necrosis in normothermic rats.

257 t the end of hypothermia in hypothermic (vs. normothermic) rats (p <.05), indicating that hypothermia

258 ncentrations were higher in hypothermic (vs. normothermic) rats at the end of both hypothermia and re

259 Abdominal normothermic regional perfusion (aNRP) for donation afte

260 Normothermic regional perfusion (NRP) allows in situ ass

261 Normothermic regional perfusion (NRP) and normothermic m

262 in 2015 under a protocol based on the use of normothermic regional perfusion (NRP) before organ procu

263 A period of normothermic regional perfusion (NRP) in the donor may r

264 In situ normothermic regional perfusion (NRP) or restarting the

265 protocol of cDCD liver transplant (LT) with normothermic regional perfusion (NRP) preservation.

266 In situ normothermic regional perfusion (NRP) restores a blood s

267 We developed a novel protocol for in situ normothermic regional perfusion (NRP) which complied wit

268 (in situ cooling [ISC]) or 33-36 degrees C (normothermic regional perfusion [NRP]).

269 or the determination of death, or the use of normothermic regional perfusion for the in situ preserva

270 Normothermic regional perfusion has been reported to imp

271 Normothermic regional perfusion has shown to be critical

272 recovery and preservation include the use of normothermic regional perfusion in the donor and ex vivo

273 Normothermic regional perfusion used during DCD abdomina

274 rculatory arrest does not prevent successful normothermic regional perfusion.

275 Peroxynitrite anions may play a role in normothermic renal ischemia and reperfusion.

276 Herein, we report the first case of ex vivo normothermic renal transplant perfusion in man.

277 in the hippocampus were elevated at 16 h of normothermic reperfusion versus 48 h with BC reperfusion

278 ress of simulated transplantation by ex vivo normothermic reperfusion with blood.

279 C) CP (St Thomas II) followed by 30 minutes normothermic reperfusion.

280 hermia for 30 minutes followed by 2 hours of normothermic reperfusion.

281 University of Wisconsin solution after 1 hr normothermic reperfusion.

282 q/L K+, 4 degrees C) for 2 hours followed by normothermic reperfusion; and (3) preconditioning/cardio

283 tly better than delayed post-ROSC cooling or normothermic resuscitation.

284 d under both hypothermic (1-8 degrees C) and normothermic settings.

285 protein level of beta-catenin degraded after normothermic stroke.

286 r marginal quality donor lungs, extension of normothermic support beyond 6 h has been challenging.

287 onal and histological recovery after 24 h of normothermic support.

288 vs. 42%, p < .001), spent more percent time normothermic (T < or =37.2 degrees C, 59% vs. 3%, p < .0

289 In both settings, hypothermic and normothermic techniques are in clinical use.

290 72F) mutation regulates p53 stability at the normothermic temperature, but it is the increased recrui

291 with organ preservation steering toward (sub)normothermic temperatures, bacterial contamination may b

292 Compared with adults who were kept normothermic, those who underwent therapeutic hypothermi

293 cant difference between the hyperthermic and normothermic tissue; there was a large increase in sodiu

294 markedly greater when compared to LBNP while normothermic (torso: 73 +/- 2%; heart: 72 +/- 3%; spleen

295 ons, but did not change CVC in either of the normothermic trials.

296 lowing cardiopulmonary bypass (normotensive, normothermic) using mixed-model analysis of variance.

297 tility after PCO cardioplegia was similar to normothermic values in control (57+/-2 microm/s) and CHF

298 l temperature, arterial PCO2 was restored to normothermic values using end-tidal forcing.

299 e 34 degrees C; and in group 4 (n = 5), with normothermic venovenous shunt.

300 Hearts were subjected to 30 min of normothermic, zero-flow ischemia followed by 30-min repe