ライフサイエンスコーパス: noxious stimuli

1 hyperalgesia (exaggerated responsiveness to noxious stimuli).

2 us stimuli (learned anorexia associated with noxious stimuli).

3 ses hyperalgesia, an enhanced sensitivity to noxious stimuli.

4 ne if methylene blue could protect RGCs from noxious stimuli.

5 part of the inflammatory response to inhaled noxious stimuli.

6 nilloid 1(TRPV1), an important transducer of noxious stimuli.

7 ody's way of combating invading pathogens or noxious stimuli.

8 in protecting the cell against stressful and noxious stimuli.

9 Both DRR and AR can be evoked by noxious stimuli.

10 e healing and neoangiogenesis in the face of noxious stimuli.

11 mucosal tissues and protects organisms from noxious stimuli.

12 10, were persistently activated by transient noxious stimuli.

13 uring evaluation of the spatial locations of noxious stimuli.

14 actions of CO in modulating the response to noxious stimuli.

15 ective mechanism, the cornea is sensitive to noxious stimuli.

16 tentiation of endogenous opioid responses to noxious stimuli.

17 either protein display altered responses to noxious stimuli.

18 osure of cardiomyocytes to hypoxia and other noxious stimuli.

19 for optimizing their role in transmission of noxious stimuli.

20 t, Klf7(-/-) mice have deficient response to noxious stimuli.

21 eption to both thermal and chemical visceral noxious stimuli.

22 lator of the responses of sensory neurons to noxious stimuli.

23 ne of defense against invading pathogens and noxious stimuli.

24 allodynia-a painful response to normally non-noxious stimuli.

25 and upregulate c-Fos protein in response to noxious stimuli.

26 responding preferentially to threatening or noxious stimuli.

27 and humans display two types of response to noxious stimuli.

28 nto how EGFR integrates responses to diverse noxious stimuli.

29 myelinated nerve fibers (C-fibers) following noxious stimuli.

30 intercellular communications in response to noxious stimuli.

31 (JNK) is activated when cells are exposed to noxious stimuli.

32 central nociceptive neurons to innocuous and noxious stimuli.

33 st cells with this receptor are activated by noxious stimuli.

34 ion whilst attention is distracted away from noxious stimuli.

35 e fields (RFs) excited by non-noxious and/or noxious stimuli.

36 sensory neurons and is activated by multiple noxious stimuli.

37 ing the response of sensory nerve endings to noxious stimuli.

38 uli and a mild increased sensitivity to some noxious stimuli.

39 seline hindpaw sensitivity to non-noxious or noxious stimuli.

40 , to significantly attenuated sensitivity to noxious stimuli.

41 ation without diminishing responses to other noxious stimuli.

42 rn and is released in response to painful or noxious stimuli.

43 eficient in their responses to each of these noxious stimuli.

44 ne signals to the brain and in responding to noxious stimuli.

45 g in a decreased pain response to peripheral noxious stimuli.

46 vous system analyzes cutaneous innocuous and noxious stimuli.

47 d a high firing rate but responded weakly to noxious stimuli.

48 ition is dynamically activated by peripheral noxious stimuli.

49 P N-terminal activity in mice not exposed to noxious stimuli.

50 prolonged the after-discharge in response to noxious stimuli.

51 een strongly implicated in the processing of noxious stimuli.

52 e pain is an unpleasant experience caused by noxious stimuli.

53 espond over a range of natural innocuous and noxious stimuli.

54 raspinal processing of, and responsivity to, noxious stimuli.

55 s demonstrates that these neurons respond to noxious stimuli.

56 al responsiveness and adaptation to repeated noxious stimuli.

57 oxytocin (OXT) neurons in the processing of noxious stimuli.

58 or cell viability during exposure to various noxious stimuli.

59 arly stage of lung inflammatory responses to noxious stimuli.

60 O mice responded normally to a wide array of noxious stimuli.

61 ugmented glucose mobilization in response to noxious stimuli.

62 sent a way for dopamine to modulate incoming noxious stimuli.

63 unicate to us their perceived levels of such noxious stimuli.

64 or for heat, acidic pH, capsaicin, and other noxious stimuli.

65 v1.7 plays a crucial role in transmission of noxious stimuli.

66 e in thermosensation and perception of other noxious stimuli.

67 rain region mediating affective responses to noxious stimuli.

68 ment neuronal sensitivity (sensitization) to noxious stimuli.

69 racolumbar skin and is selectively driven by noxious stimuli.

70 udes the whole spectrum from gentle touch to noxious stimuli.

71 ferent nociceptors and is activated by other noxious stimuli.

72 retinal cells die in response to a range of noxious stimuli.

73 o associated with the perception of pain and noxious stimuli.

74 ating homeostatic responses against external noxious stimuli.

75 n the magnitude and duration of responses to noxious stimuli.

76 nsory neurons that are activated by painful (noxious) stimuli.

77 Localized noxious stimuli (55 degrees C or intradermal injection o

78 ify and process distinct sensory features of noxious stimuli according to top-down task demands.

79 However, in the majority of cases, noxious stimuli activate multiple terminals; thus, the o

80 inhalation and intravenous injection of the noxious stimuli allyl isothiocyanate (AITC).

81 Transient noxious stimuli also enhanced MCC excitability, and this

82 (KO) mice had normal responses to acute non-noxious stimuli and a mild increased sensitivity to some

83 s that assemble in response to infectious or noxious stimuli and activate the CASPASE-1 protease.

84 Laminae that are responsive to non-noxious stimuli and activated by walking, IIi, nucleus p

85 are responsive to a variety of modalities of noxious stimuli and can signal pain even when activated

86 and activity mediates a hypersensitivity to noxious stimuli and causes the inhibition of opiate effi

87 By sensing noxious stimuli and contributing to the necessary reacti

88 rsal root ganglion (DRG) neurons that detect noxious stimuli and elicit pain.

89 oid receptor in the VPMpc respond to various noxious stimuli and fear memory.

90 lp to predict how nociceptive neurons encode noxious stimuli and how this encoding changes in patholo

91 that the sexes differ in their perception of noxious stimuli and in their responsivity to exogenous a

92 l A1 (TRPA1) ion channel senses a variety of noxious stimuli and is involved in nociception.

93 coeruleus are involved in the processing of noxious stimuli and may contribute to anti-nociceptive m

94 but markedly attenuated responses to highly noxious stimuli and mechanical and thermal hyperalgesia.

95 avioural responses to thermal and mechanical noxious stimuli and morphine-induced antinociception.

96 Responses to normally noxious stimuli and motor function were unchanged in SCI

97 sured by nerve conduction, gait, response to noxious stimuli and nerve histology.

98 cortex potently suppresses SpVc responses to noxious stimuli and produces behavioral hypoalgesia.

99 s by which the brain protects itself against noxious stimuli and recovers from ischaemic damage are a

100 it permits responses such as withdrawal from noxious stimuli and regulation of body temperature.

101 Spinal cord neurons respond to peripheral noxious stimuli and relay this information to higher bra

102 he sea slug Pleurobranchaea are responses to noxious stimuli and replace orienting turns to food stim

103 rons in the peripheral nervous system detect noxious stimuli and report the information to the centra

104 olution are critical in ensuring disposal of noxious stimuli and return to homeostasis.

105 orsal root ganglia (DRG) neurons that detect noxious stimuli and signal pain.

106 etween supraspinal and spinal sites to acute noxious stimuli and suggest possibility that compounds a

107 and mark dying cells in response to diverse noxious stimuli and suggest that elaborate, multilayered

108 n in preventing endothelial cell death after noxious stimuli and suggest that the ICE pathway may med

109 a pivotal role in the transmission of highly noxious stimuli and the maintenance of hyperalgesia.

110 ) is implicated in the affective response to noxious stimuli and the motivational properties of condi

111 sion that underlies increased sensitivity to noxious stimuli and the perception of non-noxious stimul

112 estigated whether it increases resistance to noxious stimuli and the role of changes in intracellular

113 relevant doses affects the ability to detect noxious stimuli and therefore should be considered when

114 e disorder characterized by insensitivity to noxious stimuli and variable intellectual disability (ID

115 TRPA1 is a unique sensor of noxious stimuli and, hence, a potential drug target for

116 nociceptors (sensory neurons that respond to noxious stimuli), and that blocking its synthesis would

117 Finally, we show that the neural coding of noxious stimuli, and consequent experience of pain, are

118 ressed in neurons that sense temperature and noxious stimuli, and TrkC is expressed in proprioceptive

119 encounters with predators, competitors, and noxious stimuli, animals have evolved defensive response

120 taneous activity and responded vigorously to noxious stimuli applied to any part of the body surface.

121 sula, and ACC when comparing the response to noxious stimuli applied to control and placebo cream-tre

122 induced siphon withdrawal reflex by repeated noxious stimuli applied to one of three sites: the (1) i

123 whether stimulation of peripheral nerves by noxious stimuli applied to their receptive fields activa

124 Aggression and responsiveness to noxious stimuli are adaptable traits that are ubiquitous

125 Here, we show that graded encodings of noxious stimuli are categorized in a decision-associated

126 pain hypersensitivity.SIGNIFICANCE STATEMENT Noxious stimuli are detected by terminal endings of prim

127 ulation and nocifensive responses to thermal noxious stimuli are not modified.

128 n as to how such distinct sensory aspects of noxious stimuli are processed by the human brain.

129 Noxious stimuli are sensed and carried to the spinal cor

130 to noxious stimuli and the perception of non-noxious stimuli as painful.

131 ls, allowing rapid, coordinated responses to noxious stimuli, as well as to bacterial and fungal path

132 the ACC to increase the aversive response to noxious stimuli at anatomically unrelated sites.

133 he response of the brain reward circuitry to noxious stimuli at baseline before opioid administration

134 Containment of the glial HO-1 response to noxious stimuli at strategic points of the life cycle ma

135 The ion channel TRPA1 detects noxious stimuli at the plasma membrane of neurons and el

136 whereby noradrenaline may suppress incoming noxious stimuli at the primary synaptic afferents in the

137 redicted by the neuronal response to painful noxious stimuli before infusion in key structures of the

138 e studied for sensitivity to non-noxious and noxious stimuli, before and after induction of experimen

139 diversity in their functions and respond to noxious stimuli between brain regions.

140 fferences in brain activation in response to noxious stimuli between patients and healthy controls we

141 Activation of nociceptor sensory neurons by noxious stimuli both triggers pain and increases capilla

142 distal limbs have a high spatial acuity for noxious stimuli but a low density of pain-sensing neurit

143 espond to beta-alanine, heat, and mechanical noxious stimuli but do not respond to histamine.

144 peripheral and spinal nociceptive neurons to noxious stimuli but only when the joint was inflamed.

145 fit trait that defends against pathogens and noxious stimuli but whose overactivation can result in i

146 ally cause pain and pain usually arises from noxious stimuli, but exceptions to these apparent truism

147 hibited normal behavioral responses to acute noxious stimuli, but subsequent to partial sciatic nerve

148 vating nociceptor sensory neurons respond to noxious stimuli by initiating protective responses inclu

149 within the vasculature and tissue respond to noxious stimuli by sending out coordinated signals that

150 ain results from the detection of intense or noxious stimuli by specialized high-threshold sensory ne

151 underlying the detection and transmission of noxious stimuli by the peripheral nervous system.

152 s specialized to detect painful or otherwise noxious stimuli can respond to bacterial pathogens.

153 All three types of noxious stimuli caused a depletion of CGRP from corneal

154 The nociceptive system of detecting noxious stimuli comprises two classes of peripheral affe

155 These findings suggest that multiple noxious stimuli converge upon a peptidase-driven, core s

156 firmed that the escape/avoidance response to noxious stimuli corresponds to changes in neural activat

157 cterized by hypersensitivity to innocuous or noxious stimuli during sustained opiate administration.

158 d by heat >42 degrees C in addition to other noxious stimuli, e.g. acids and vanilloids.

159 b neurons augments the autonomic response to noxious stimuli, ensuring sufficient glucose mobilizatio

160 ttle is known about the proteins that detect noxious stimuli, especially those of a physical nature.

161 Noxious stimuli evoke a range of acute and long-lasting

162 nent of the cellular mechanism through which noxious stimuli evoke pain.

163 al nerves, indicating that all modalities of noxious stimuli evoked peptide release.

164 We found that a variety of noxious stimuli evoked strong responses in ASH including

165 1, a channel implicated in detecting several noxious stimuli, exhibiting a 50% effective concentratio

166 sensation, as well as in hypersensitivity to noxious stimuli following tissue injury.

167 olved highly efficient mechanisms to "flush" noxious stimuli from airway surfaces by selective activa

168 e body, are the first stage of communicating noxious stimuli from the periphery to central nervous sy

169 he mechanisms underlying the transduction of noxious stimuli from the viscera, suggest that the inves

170 ds to profoundly increased pain sensitivity: noxious stimuli generate a greater response and stimuli

171 hronic pain: it is initiated by a variety of noxious stimuli, has indefinite duration, and pain appea

172 t long-lasting changes in reflexes evoked by noxious stimuli have evolved to enhance reflex protectio

173 Noxious stimuli have motivational power and can support

174 orphine on evoked responses of LC neurons to noxious stimuli have not been systematically examined.

175 on neurons: the majority of these respond to noxious stimuli, however some are activated by cooling.

176 ions) modulate behavioral responses to acute noxious stimuli; however, little is known about the endo

177 persistent pain, an exacerbated response to noxious stimuli (hyperalgesia), and a lowered pain thres

178 We found that intense noxious stimuli (i.e., subdermal injection of capsaicin

179 S1 axon terminals increases the response to noxious stimuli in ACC neurons.

180 opioid release in the spinal cord evoked by noxious stimuli in anesthetized rats.

181 sation and neural circuitry that result from noxious stimuli in early life.

182 Experiments comparing brain responses to noxious stimuli in fMRI between patients and controls we

183 ascending pain pathway occurred during acute noxious stimuli in healthy individuals.

184 tive suckling produce analgesia to transient noxious stimuli in infant rats and humans.

185 induced suppression of neuronal responses to noxious stimuli in key structures of the descending pain

186 the receptor by setting sensitivity to other noxious stimuli in response to changes in extracellular

187 havioral and neurophysiological responses to noxious stimuli in rodents when administered systemicall

188 al and subcortical responses to auditory and noxious stimuli in sedated and unresponsive states.

189 rol the transduction of inflammation-induced noxious stimuli in sensory neurons.

190 tive cation channels that integrate multiple noxious stimuli in sensory neurons.

191 e amygdala did not affect responses to acute noxious stimuli in the absence of inflammation, indicati

192 anism for noradrenaline to modulate incoming noxious stimuli in the dorsal horn of the spinal cord.

193 or a lateralized response to noxious and non-noxious stimuli in the human spinal cord.

194 ulation of orienting and attack by low-level noxious stimuli in the hungriest animals may reflect ris

195 eby serving important functions in detecting noxious stimuli in the sensory system and pathological s

196 vel NPVF-vRN functional circuit modulated by noxious stimuli in vertebrates.

197 ial vanilloid 1 (TRPV1), a key integrator of noxious stimuli, in the pathogenesis of pancreatic pain

198 VR1 responds to noxious stimuli including capsaicin, the pungent compone

199 the capsaicin receptor, is an integrator of noxious stimuli including heat and extracellular acidic

200 lion neurones and is activated by a range of noxious stimuli including irritant chemicals, acids and

201 rapid and complex physiological reaction to noxious stimuli including microbial pathogens.

202 A variety of noxious stimuli, including balloon angioplasty, may comp

203 nel that can be activated by a wide range of noxious stimuli, including capsaicin, acid, and heat.

204 nel that can be activated by a wide range of noxious stimuli, including capsaicin, acid, and heat.

205 TRPA1 is activated by a variety of noxious stimuli, including cold temperatures, pungent na

206 Polymodal nociceptors detect noxious stimuli, including harsh touch, toxic chemicals

207 The TRPV1 channel is a detector of noxious stimuli, including heat, acidosis, vanilloid com

208 TRPV1 functions as a molecular integrator of noxious stimuli, including heat, low pH, and chemical li

209 iple different infectious, inflammatory, and noxious stimuli, including pneumococcal pneumonia.

210 that detect odors, tastants, pheromones, and noxious stimuli, including receptors of the odor recepto

211 We tested the hypothesis that noxious stimuli induce pain modulation by activation of

212 results indicate that lumbar opiates inhibit noxious stimuli-induced neurotransmitter release from pr

213 Cutaneous TRPV1(+) neurons directly sense noxious stimuli, inflammatory cytokines, and pathogen-as

214 Noxious stimuli inhibit inflammation by activating neuro

215 ential functions of nociceptors--transducing noxious stimuli into depolarizations that trigger action

216 Hyperalgesia to noxious stimuli is accompanied by increased spinal cyclo

217 detect and encode the information regarding noxious stimuli, is crucial in determining pain sensatio

218 creasingly greater pain evoked by repetitive noxious stimuli, is highly variable between individuals.

219 fibrosis airways are recurrently exposed to noxious stimuli, leading to epithelial injury.

220 nociceptors, the sensory neurons that detect noxious stimuli, leading to pain and itch.

221 ors, for example), especially in response to noxious stimuli (learned anorexia associated with noxiou

222 s, sensory pathways mediating appetitive and noxious stimuli may have dual access to neural networks

223 s, which reflect sensory properties of acute noxious stimuli, NAc activity in humans encodes its pred

224 nce suggests that nerve fibers responding to noxious stimuli (nociceptors) modulate immunity in a var

225 he activation of sensory neurons that detect noxious stimuli (nociceptors).

226 r thoracic spinal neurons responding to both noxious stimuli of the heart and lungs in rats.

227 The effect of various noxious stimuli on sensory and enteric neural function i

228 In response to invading microbes, noxious stimuli, or tissue injury, an acute inflammatory

229 in the ICU in order for patients to tolerate noxious stimuli, particularly mechanical ventilation.

230 d dorsal horn neuron activity in response to noxious stimuli, possibly through a release of GABA.

231 ts keratinocyte proliferation in response to noxious stimuli, possibly through p53 activation, which

232 ndogenous ion channels that are activated by noxious stimuli, primarily TRPV1.

233 The ability to detect noxious stimuli, process the nociceptive signal, and eli

234 Hyperalgesia is an exaggerated response to noxious stimuli produced by peripheral or central plasti

235 Cutaneous sensory neurons that detect noxious stimuli project to the dorsal horn of the spinal

236 eased by the olfactory epithelium (OE) after noxious stimuli provides a physiological source for a ne

237 NGF in behavioral responses of adult rats to noxious stimuli, providing high titers of antibody are p

238 on, in healthy mice increases sensitivity to noxious stimuli (referred to as 'pain') without general

239 evention of harm in the presence of novel or noxious stimuli, regardless of whether such stimuli are

240 eurons and vRN are suppressed and excited by noxious stimuli, respectively.

241 is normally attenuated after elimination of noxious stimuli, restoration of homeostasis and initiati

242 We also observed that repetitive noxious stimuli resulted in adaptation of the signal.

243 During noxious stimuli, serotonergic neurons activation was due

244 sic nocebo responses to identical calibrated noxious stimuli showed signal increases in brain regions

245 to maintain pancreatic health in response to noxious stimuli such as alcohol.

246 Exposure to noxious stimuli such as hyperoxia, volutrauma, and infec

247 ory neurons that sense potentially damaging (noxious) stimuli such as high temperature, harsh mechani

248 o recorded L-ITCcs are strongly activated by noxious stimuli, such as hindpaw pinches or electrical f

249 To escape noxious stimuli, such as parasitoid wasp attacks, Drosop

250 begins when sensory neurons are activated by noxious stimuli, such as stepping on a tack.

251 ome c oxidase and protect RGCs against these noxious stimuli supports its suggested mechanism of acti

252 any endogenous opioids that are released by noxious stimuli target presynaptic MORs or delta-opioid

253 pain intensity ratings of acute experimental noxious stimuli than age-matched control subjects.

254 ts identify the amygdalar representations of noxious stimuli that are functionally required for the n

255 oot ganglia (DRG) neurons are key sensors of noxious stimuli that are released under inflammatory con

256 nderlie detection, coding, and modulation of noxious stimuli that generate pain.

257 gerated hyperalgesic behavior in response to noxious stimuli that may model aspects of painful diabet

258 in nociceptive processing during persistent noxious stimuli that resemble pathological pain conditio

259 Inflammation is a protective response to noxious stimuli that unavoidably occurs at a cost to nor

260 expectancy modulates activations produced by noxious stimuli through a distinct modulatory network th

261 in, and suppress the overall withdrawal from noxious stimuli through a pathway requiring the opioid-l

262 of pain is initiated by the transduction of noxious stimuli through specialized ion channels and rec

263 n sensation is initiated by the detection of noxious stimuli through specialized transduction ion cha

264 scription of the processing of innocuous and noxious stimuli throughout the intact DH.

265 the spinal cord following intense peripheral noxious stimuli, tissue injury or nerve damage.

266 in cocoa for 14days prior to an injection of noxious stimuli to cause acute or chronic excitation of

267 atiation state interacts with appetitive and noxious stimuli to determine feeding and avoidance respo

268 All animals must detect noxious stimuli to initiate protective behavior, but the

269 EC cells detect and transduce noxious stimuli to nearby mucosal nerve endings(3,6) but

270 nal activity is necessary and sufficient for noxious stimuli to produce an aversive teaching signal.

271 Neurodegenerative diseases and noxious stimuli to the brain enhance transcription of se

272 ensory neurons that convey information about noxious stimuli to the central nervous system.

273 ays an important role in the transduction of noxious stimuli to the spinal cord.

274 elimination of evoked pain; (v) although non-noxious stimuli to the unaffected limb were perceived as

275 he transition of the neural state induced by noxious stimuli toward the outcome of non-nocifensive ac

276 In addition, several noxious stimuli trigger the release of intracellular spe

277 As a sensor for noxious stimuli, TRPV1 channel has been described as a k

278 dies) and cellular reactions to a variety of noxious stimuli (ubiquitinated dystrophic neurites, astr

279 This treatment left responses to mild noxious stimuli unchanged, but markedly attenuated respo

280 We found, however, that noxious stimuli, under normal or inflammatory conditions

281 Noxious stimuli usually cause pain and pain usually aris

282 sture (e.g., escape behaviors in response to noxious stimuli vs freezing in response to fear-evoking

283 The response of GiA cells to noxious stimuli was abolished by transection of only the

284 ailure to perceive or respond to auditory or noxious stimuli was associated with a reduction in the f

285 A series of auditory and noxious stimuli was presented to eight healthy volunteer

286 ptor potential channel that is responsive to noxious stimuli, was required for the fructose response.

287 PV channels inhibits behavioral responses to noxious stimuli, we found that both mechanoreceptor curr

288 ulation in freely behaving mice encountering noxious stimuli, we identified a distinct neural ensembl

289 For both innocuous and noxious stimuli, we observed a signal change in the prim

290 OFF cells) by noxious cutaneous stimulation, noxious stimuli were applied during evoked BAT temperatu

291 The cytoprotective effects of rhPRL against noxious stimuli were assessed by flow cytometry (tetrame

292 Acute illness and noxious stimuli were associated with 24% and 23% of the

293 The noxious stimuli were heel lances performed for routine b

294 Application of noxious stimuli, which often signal the need to mobilize

295 ting responses from being directly evoked by noxious stimuli while also facilitating the ability of f

296 Many organisms respond to noxious stimuli with defensive maneuvers.

297 sonance imaging, we compared self-controlled noxious stimuli with physically identical stimuli that w

298 behaviors without altering the detection of noxious stimuli, withdrawal reflexes, anxiety, or reward

299 the preinfusion period neuronal response to noxious stimuli within the ventral tegmentum.

300 Comparison of the noxious and non-noxious stimuli yielded several new insights into neural