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1 on to the previously identified sites (i.e., nuclear membranes).
2 romatin fibers with lamin proteins along the nuclear membrane.
3 dditional ESCRT-III proteins to holes in the nuclear membrane.
4 sprin-1 and KLC-1/2 interaction at the outer nuclear membrane.
5 cell or in trafficking of the capsid to the nuclear membrane.
6 (NE) at fusion sites of the inner and outer nuclear membrane.
7 d consist of chromatin surrounded by its own nuclear membrane.
8 6-10 foci that dynamically interact with the nuclear membrane.
9 k lining the nucleoplasmic side of the inner nuclear membrane.
10 erevisiae to the INM as opposed to the outer nuclear membrane.
11 ucing variability in the arrival time at the nuclear membrane.
12 d an SRD-YFP fusion localize with AAL to the nuclear membrane.
13 came a muscle-specific resident of the inner nuclear membrane.
14 d depth until they fused with the flat outer nuclear membrane.
15 eading to its rapid degradation at the inner nuclear membrane.
16 at links repressive chromatin with the inner nuclear membrane.
17 the association of pSmad3 with Imp8 and the nuclear membrane.
18 a cells indicate that SINC targets the inner nuclear membrane.
19 amina and particle budding through the inner nuclear membrane.
20 nd delivered by membrane fusion at the outer nuclear membrane.
21 mediate lamin filaments that lines the inner nuclear membrane.
22 C) and are required for budding at the inner nuclear membrane.
23 ant form of lamin A (termed progerin) to the nuclear membrane.
24 erstanding how capsids bud through the inner nuclear membrane.
25 of emerin, an integral protein of the inner nuclear membrane.
26 t grow radially from rafted receptors to the nuclear membrane.
27 ructure and function, primarily at the inner nuclear membrane.
28 an interaction between OGT and PIP(3) at the nuclear membrane.
29 lapse the nucleus and drive infolding of the nuclear membrane.
30 embrane, and SUN proteins crossing the inner nuclear membrane.
31 a fatty acylated repair factor at the inner nuclear membrane.
32 uggest that its primary role is at the outer nuclear membrane.
33 ion in the cell: the plasma membrane and the nuclear membrane.
34 y applying a transient tensile stress to the nuclear membrane.
35 lasmic reticulum to a subdomain of the inner nuclear membrane.
36 ned) information to protein complexes in the nuclear membrane.
37 ells) was sufficient to cause rupture of the nuclear membrane.
38 inuclear space surrounded by inner and outer nuclear membranes.
39 ase torsinA on its ability to associate with nuclear membranes.
40 s unclear how this complex is able to engage nuclear membranes.
41 evenly spaced bilayers, the inner and outer nuclear membranes.
42 cilitated by microtubules, which pull on the nuclear membranes.
43 h the formation of the NEC and remodeling of nuclear membranes.
44 g the previously reported undulations of the nuclear membranes.
45 sprouting filopodia-like spikes towards the nuclear membranes.
46 ented insights on ER tubules and sheets, and nuclear membranes.
47 S315 is involved in CCTalpha recruitment to nuclear membranes.
48 nucleus that deform it and cause rupture of nuclear membranes.
49 narrower spaces between the inner and outer nuclear membranes, (3) reduced numbers of nuclear pores
51 at lamin A/C, but not lamin B2, protects the nuclear membranes against rupture from tensile stress.
53 imaged single nuclear pore complexes in the nuclear membrane and aggregates of GFP-conjugated Tau pr
54 critical for processing lamin A on the inner nuclear membrane and clearing clogged translocons on the
55 otein mesh that resides underneath the inner nuclear membrane and consists of lamins and lamina-assoc
57 zed to hydrophobic perinuclear features, the nuclear membrane and inside the nucleus within minutes.
58 lso demonstrate that TMEM43 localizes at the nuclear membrane and interacts with emerin and beta-acti
60 , Kuduk (Kud), which can reside at the outer nuclear membrane and is required for the development of
61 eases in O(2)(-) (3.5-fold; P<0.01) from the nuclear membrane and nuclear exit of HDAC4 in cardiomyoc
62 omplex (NEC), which is anchored to the inner nuclear membrane and provides a scaffold for the assembl
63 or protein expression forms a complex at the nuclear membrane and remodels these membranes to generat
64 ids undergo primary envelopment at the inner nuclear membrane and secondary envelopment at organelles
65 mplex consists of KASH proteins in the outer nuclear membrane and SUN proteins in the inner nuclear m
66 ibility that protein regulation at the inner nuclear membrane and the nuclear lamina contributes to t
67 e-controlled breakdown and reassembly of the nuclear membrane and the restoration of transcription af
68 -type virus recruits protein kinase C to the nuclear membrane and triggers its activation, whereas th
69 ristic accumulation of capsids away from the nuclear membrane, and an overall defect in nuclear impor
70 l regulators to ensure that mitotic spindle, nuclear membrane, and nuclear pore assembly occur exclus
71 ades identify interactions at the tonoplast, nuclear membrane, and pollen tube plasma membrane, empha
72 mposed of KASH proteins traversing the outer nuclear membrane, and SUN proteins crossing the inner nu
73 , traffic from the location of fusion to the nuclear membrane, and undergo the process of uncoating,
74 ted cellular fractions, including cytosolic, nuclear, membrane, and mitochondrial protein extracts.
75 Lipid microdomains localized in the inner nuclear membrane are considered platforms for active chr
77 ges in the separation of the inner and outer nuclear membrane are responsible for the additional fluc
80 emonstrate for the first time that the inner nuclear membrane Asi proteins function in a degradation
83 [4, 5] that requires A-type lamin, an inner nuclear membrane-associated protein, to accelerated agin
84 ivity of 5-lipoxygenase mutations that delay nuclear membrane association and disrupt product formati
88 oreover, with the divergence of preocclusion nuclear membrane breakdown in betabaculoviruses and memb
89 l contact with genomic DNA from the time the nuclear membrane breaks down in prometaphase until early
92 t rejoin daughter nuclei are associated with nuclear membrane but devoid of lamin and nuclear pore co
93 nuclear lamina, nuclear pore complexes, and nuclear membrane, but it is distinct from nuclear envelo
94 f TAG storage capacity, Pah1 still binds the nuclear membrane, but lipid precursors are redirected to
95 69 in the nucleus and can be tethered to the nuclear membrane by virtue of its interaction with the w
98 d of proteins within the inner and the outer nuclear membranes, connects the nuclear lamina to the cy
99 es of NI in NAFLD: inclusions bounded by the nuclear membrane, containing degenerative cell organelle
100 to the protein lamina network and the outer nuclear membrane continuous with the endoplasmic reticul
101 ; 2) intracellular mechanics of cellular and nuclear membranes, contractile actin stress fibers, and
103 ng intralumenal vesicles fuse with the outer nuclear membrane, delivering the capsids to the cytoplas
104 inations incorporating SERCA1 in their outer nuclear membranes demarcate further diverse networks of
106 are expressed together, numerous virion-size nuclear membrane-derived vesicles were evident at the nu
109 sphorylations required for the initiation of nuclear membrane disassembly during mitosis are adapted
111 itro resembles capsid budding into the inner nuclear membrane during HSV-1 infection and nuclear enve
114 thought to receive arachidonic acid from the nuclear membrane-embedded 5-LOX-activating protein (FLAP
115 at generation and maintenance of NP requires nuclear membrane expansion, actin, and the exocyst compl
118 ne encompassing the acentrics fuses with the nuclear membrane, facilitating integration of the acentr
119 cell diameter, low cell stiffness, and high nuclear membrane fluctuations are highly clonogenic and
121 egress, herpesvirus capsids bud at the inner nuclear membrane forming perinuclear viral particles tha
122 promotes chromosome coalescence, preventing nuclear membranes from enwrapping individual chromosomes
123 he recruitment of p-PKC-delta and Cap to the nuclear membrane, hence abolishing the phosphorylation o
125 ecture and vital biological functions of the nuclear membranes, how they achieve and maintain such a
126 I components to a virus egress domain on the nuclear membrane.IMPORTANCE The ESCRT system is hijacked
128 topic membrane protein residing in the inner nuclear membrane in association with the nuclear lamina.
129 antibody gave very specific labeling of the nuclear membrane in healthy neurons, with apparent reloc
130 rved that NOX4 and p22(phox) localize to the nuclear membrane in MV4-11 cells expressing FLT3-ITD.
132 a smaller amount of CA than complexes at the nuclear membrane, in the cytoplasm, or in controls.
133 amily of transmembrane proteins of the inner nuclear membrane (INM) [8, 9], to form the so-called LIN
136 ion to uncover new constituents of the inner nuclear membrane (INM) by comparative BioID analysis of
137 membrane proteins are targeted to the inner nuclear membrane (INM) by diffusion within the membrane
140 tanding the protein composition of the inner nuclear membrane (INM) is fundamental to elucidating its
142 w that the ESCRT Chm7 and the integral inner nuclear membrane (INM) protein Heh1 are spatially segreg
144 riched for subsets of nucleoporins and inner nuclear membrane (INM) proteins, which associate with di
147 ptor 5 (mGluR5) is concentrated at the inner nuclear membrane (INM) where it mediates Ca(2+) changes
148 Cargo is recruited, enveloped at the inner nuclear membrane (INM), and delivered by membrane fusion
149 otein 1 (SUN1), which localizes to the inner nuclear membrane (INM), are part of the linker of nucleo
150 s were dome-shaped evaginations of the inner nuclear membrane (INM), that grew in diameter and depth
160 evidence that nesprin-2G localization to the nuclear membrane is altered under high-force conditions.
161 iffusion, the probability of AR crossing the nuclear membrane is an important factor in determining t
162 We also see that human torsinA at the inner nuclear membrane is associated with membrane expansion a
166 (LINC) complex, composed of outer and inner nuclear membrane Klarsicht, ANC-1, and Syne homology (KA
167 results indicate that VP4 forms pores in the nuclear membrane leading to lysis and virus release.
170 Ca(2+) signals are generated by a complex of nuclear membrane-localised ion channels including the DO
171 nd revealed only partial colocalization with nuclear membrane markers, probably due to post-mortem ti
172 rafficking of envelope proteins to the inner nuclear membrane, mediated partly through the FP25K prot
173 re increase, hydroxyl radical production and nuclear membrane modifications on the treatment outcome.
174 entrosome number, primary cilium morphology, nuclear membrane morphology, chromosome segregation, mit
175 nucleus during neuronal migration result in nuclear membrane (NM) ruptures, causing interspersion of
179 acidic pH did not induce these currents, and nuclear membranes obtained from cells expressing rat IP(
182 ic chemical signal, the arrival times at the nuclear membrane of proteins that are activated at the c
186 d1/UNC-84 (SUN) proteins interact with outer nuclear membrane (ONM) Klarsicht/ANC-1/Syne homology (KA
187 ng loss, encodes nesprin-4 (NESP4), an outer nuclear membrane (ONM) protein expressed in the hair cel
188 amma-tubulin, depends on Nesprin-1, an outer nuclear membrane (ONM) protein that connects the nucleus
189 eticulum and then transported from the outer nuclear membrane (ONM) to the inner nuclear membrane (IN
191 earing nucleic acid, derived from either the nuclear membrane or the closely associated rough endopla
192 ents interact with many partners such as the nuclear membrane, other chromosomes or nuclear bodies, b
193 l for timely repair of large ruptures in the nuclear membrane, potentially by facilitating membrane a
194 tides in the eukaryotic cell nucleoplasm and nuclear membrane prompted us to study the putative inter
195 In this issue, Ohsaki et al. show that the nuclear membrane, promyelocytic leukemia bodies, and the
200 ly functional lysine-less mutant of an inner nuclear membrane protein in yeast, Asi2, is polyubiquity
201 n, nuclear fragmentation and cleavage of the nuclear membrane protein lamin A, expression of pro-apop
202 s) torsinA (TA) and its activator, the inner nuclear membrane protein lamina-associated polypeptide 1
203 conditional hepatocyte deletion of the inner nuclear membrane protein lamina-associated polypeptide 1
204 NE integrity, a process involving the inner nuclear membrane protein LEM2 recruiting CHMP7/Cmp7 and
205 detect elevated levels of the integral inner nuclear membrane protein MAN1, an established negative r
206 t BMAL1 is positively modulated by the inner nuclear membrane protein MAN1, which directly binds the
209 exposed dynein-binding domains in the outer nuclear membrane protein nesprin-2G, which polarizes the
210 ated the impact of ER stress on ER and inner nuclear membrane protein quality control mechanisms in S
211 Strikingly, we also find that the inner nuclear membrane protein Sun1 antagonizes Sun2 LINC comp
212 9 mice that are also deficient for the inner nuclear membrane protein Sun1 show markedly reduced tiss
214 d that LINC complexes that contain the inner nuclear membrane protein Sun2 promote focal adhesion ass
215 e identified S. cerevisiae Mps2 as the outer nuclear membrane protein that connects the LINC complex
216 ines, prompting us to test whether emerin, a nuclear membrane protein that interacts with lamins and
218 megalovirus (HCMV), this complex consists of nuclear membrane protein UL50, and nucleoplasmic protein
219 ncoding the lamin B receptor (LBR), an inner nuclear membrane protein whose expression is required fo
220 Lamin B receptor (LBR) is a bifunctional nuclear membrane protein with N-terminal lamin B and chr
221 Lamin B receptor (LBR), an integral inner nuclear membrane protein, also contains a functional C14
222 is physically associated with another inner nuclear membrane protein, Nur1, and deletion of either l
224 terphase, in part through recruitment of the nuclear membrane proteins emerin and Lem-domain-containi
225 investigate the role of fission yeast inner nuclear membrane proteins in determining nuclear size, a
226 ." We surveyed the diffusional mobilities of nuclear membrane proteins to identify proximal effects o
227 peripheral channels, finding that most inner nuclear membrane proteins use only the peripheral channe
228 he homologous architectures of related inner nuclear membrane proteins(7,8), suggest that phase separ
229 f the LEM (Lap2-Emerin-Man1) family of inner nuclear membrane proteins, and the ESCRT-II/ESCRT-III hy
232 ligomerization of the luminal domains of two nuclear membrane proteins, nesprin-2 and SUN2, which int
233 (Lap2-emerin-MAN1) family of integral inner nuclear membrane proteins, which binds to an early NPC a
236 e intermediate filaments that line the inner nuclear membrane, provide structural support for the nuc
237 Transcriptome compartmentalization by the nuclear membrane provides both stochastic and functional
238 smids to cross both cell plasma membrane and nuclear membrane quickly to promote the transgene expres
240 ticles that subsequently fuse with the outer nuclear membrane, releasing capsids into the cytoplasm.
241 irions that subsequently fuse with the outer nuclear membrane, releasing capsids into the cytosol.
242 nuclear envelope barrier would lead to local nuclear membrane remodeling to promote membrane sealing.
244 mbrane proteins in mitosis, also facilitates nuclear membrane repair in interphase, in part through r
246 with translocation from the cytoplasm to the nuclear membrane, resulting in increased membrane phosph
247 ve that untethering chromatin from the inner nuclear membrane results in highly deformable nuclei in
248 ed DNA-damage response proximal to the inner nuclear membrane, revealing a mechanism of compartmental
249 ALA + DFO showed hepatocyte autophagosomes, nuclear membrane ruffling, and porphyrin-containing vacu
255 Characterization of GFP-BAF accumulation at nuclear membrane rupture sites confirmed BAF is a fast,
257 e nucleus, causing chromatin protrusions and nuclear membrane ruptures at sites with nuclear lamina d
259 ear envelope (NE) consists of two concentric nuclear membranes separated by the lumen, an ~40-nm-wide
260 isolated nucleoplasts stripped of the outer nuclear membrane showed progressive nuclear localization
261 ects, a previously identified determinant of nuclear membrane stability, but did decrease the number
262 generates diacylglycerol from PA, targets a nuclear membrane subdomain that is in contact with growi
263 s (emerin, MAN1, LAP1, and LBR) of the inner nuclear membrane, suggesting that SINC interacts with ho
264 , we find that isolated nuclei lacking inner nuclear membrane tethers are less stiff than wild-type n
265 hromodomain protein CEC-4 bound to the inner nuclear membrane tethers heterochromatin through H3K9me(
266 observed significantly more distant from the nuclear membrane than its nontranslocated counterpart, w
267 le barriers, leading to arrival times at the nuclear membrane that are comparable to models in which
269 rm complexes with KASH proteins of the outer nuclear membrane that connect the nuclear envelope (NE)
271 ammalian dynein-binding protein of the outer nuclear membrane that forms a meiotic complex with Sun1.
272 1 (LAP1) is an integral protein of the inner nuclear membrane that has been implicated in striated mu
274 leus is fundamentally composed by lamina and nuclear membranes that enclose the chromatin, nucleoskel
276 s complex mediates capsid transit across the nuclear membrane, the regulatory components are not clea
277 romatin without prominent margination at the nuclear membrane; they exhibited small punctate nucleoli
278 smic protein UL53, which is recruited to the nuclear membrane through its interaction with UL50.
279 s duration are found effective on disrupting nuclear membrane to advance nuclear delivery of plasmid
280 ape whereby nascent capsids bud at the inner nuclear membrane to form perinuclear virions that subseq
283 ruit phosphorylated PKC-delta and Cap to the nuclear membrane to phosphorylate lamin A/C, resulting i
284 ndent and AA-independent steps that occur on nuclear membranes to control the assembly of the LT synt
285 ric structure that fuses the inner and outer nuclear membranes to form a central channel of ~60 nm in
286 tein complexes that fuse the inner and outer nuclear membranes to form channels across the nuclear en
287 red for HSV capsids to bud through the inner nuclear membrane, to the vertex-specific complex of HSV
288 ns of RNAs into discrete foci at or near the nuclear membrane triggered by multiple elements; and a n
290 sed of BFRF1 and BFLF2 was visualized at the nuclear membrane using autofluorescent protein fusions.
291 aracterizing calcium release channels in the nuclear membrane, very little is known regarding the pro
292 y biogenesis, repair of the plasma membrane, nuclear membrane vesicle formation, and HIV budding.
294 and the mechanical and dynamic properties of nuclear membranes we investigated their lipid compositio
295 ar, of which approximately 60% is located on nuclear membranes, where activation leads to sustained C
296 These F-actin spikes protrude pore-free nuclear membranes, whereas the adjoining stretches of me
297 cruitment of phosphorylated PKC-delta to the nuclear membrane, which further phosphorylates lamin A/C
298 sociation of its alpha-helical M-domain with nuclear membranes, which is negatively regulated by phos
299 otic transmembrane proteins are found on the nuclear membrane, yet how such proteins target and trans