ライフサイエンスコーパス: nucleated cell

1 d cells) and bone marrow (12.6 +/- 3.6/10(6) nucleated cells).

2 ease (MRD) had MRD-negative status (<=10(-4) nucleated cells).

3 lting in individuals with viral DNA in every nucleated cell.

4 tocyte integration results in HHV-6 in every nucleated cell.

5 viral genomes are therefore present in every nucleated cell.

6 recipients, and they received lower doses of nucleated cells.

7 istributed at diverse intracellular sites in nucleated cells.

8 ated plasma platelets activates PPARgamma in nucleated cells.

9 yrin, and spectrin, may play in nonerythroid nucleated cells.

10 lity, little is known about 4.1R function in nucleated cells.

11 of approximately 2.26 x 10(8)/kg unselected nucleated cells.

12 y mutations that affect circadian rhythms in nucleated cells.

13 exes (pMHCs) on the surface of virtually all nucleated cells.

14 FNAR1 and IFNAR2, which are expressed on all nucleated cells.

15 protein leads to multi-flagellated and multi-nucleated cells.

16 th HLA class I ligands on the surface of all nucleated cells.

17 nger RNA (mRNA) in platelets mirror those of nucleated cells.

18 rn, disarranged epidermal pattern, and round nucleated cells.

19 ty that its cytoplasmic RNA may be passed to nucleated cells.

20 biquitous protein present in mitochondria of nucleated cells.

21 llowing activation of cell-death pathways in nucleated cells.

22 signaling and transcriptional regulation in nucleated cells.

23 All complex life is composed of eukaryotic (nucleated) cells.

24 e patients contained a median of 2.3 x 10(6) nucleated cells, 1.4 x 10(6) CD34+ cells, and 1.3 x 10(4

25 in deltaAGT expression in 30% of bone marrow nucleated cells 13 weeks after transplantation.

26 most complex behaviors reported for a singly nucleated cell [16, 17].

27 n non-neural organisms [1], including singly nucleated cells [2-5] and multi-nucleate synctia [6-8].

28 ibroblastlike colonies was 8.2 +/- 0.6/10(6) nucleated cells (69.6 +/- 10/microL fetal blood).

29 an fold increase was 2.4 (range, 1.0-8.5) in nucleated cells, 82 (range, 4.6-266.4) in CFU granulocyt

30 concomitant with increased double and multi-nucleated cells, a reduced ability to undergo cytokinesi

31 lular parasite that proliferates within most nucleated cells, an important human pathogen, and a mode

32 L in that the maximal expansion by FL of the nucleated cell and progenitor pools required a longer in

33 es revealed an exponential increase in total nucleated cells and about 10-fold enhancement of nucleat

34 r direct presentation on the surface of most nucleated cells and exogenous proteins for cross-present

35 sulfate, a glycosaminoglycan associated with nucleated cells and extracellular matrices, and by elast

36 ng flows and waypoints, exist in other multi-nucleated cells and may also be generalized beyond intra

37 UCB contains a low number of nucleated cells and mostly naive T cells, resulting in p

38 ), both FL and KL enhanced the production of nucleated cells and progenitors.

39 lly, PD-L1 can be expressed on virtually all nucleated cells and suppresses the immune system by inte

40 primarily through their cytotoxicity toward nucleated cells and their ability to promote platelet ac

41 pression of hundreds of host proteins in all nucleated cells and tissues, yet many of these proteins

42 The bone marrow contained fewer nucleated cells and was enriched in myeloid progenitor c

43 st-trimester fetal liver (11.3 +/- 2.0/10(6) nucleated cells) and bone marrow (12.6 +/- 3.6/10(6) nuc

44 d platelets (anucleate cells), CHO-K1 cells (nucleated cells), and other cell types on TGT surfaces.

45 ne mononucleotide (NAD+) biosynthesis in all nucleated cells, and despite its functional ubiquity, mu

46 ermore, metabolic flux rhythms also occur in nucleated cells, and persist when the core transcription

47 aspases, which are major effector enzymes of nucleated cell apoptosis.

48 Feto-maternal transfusion of nucleated cells appears to be influenced by fetal karyot

49 Nucleated cells are continuously monitored by effector c

50 Nucleated cells are equipped with several mechanisms tha

51 Microtubule arrays in enucleated and nucleated cells are morphologically indistinguishable an

52 In particular, little is known of why viable nucleated cells are not engulfed by macrophages.

53 le when Ab-opsonized sheep erythrocytes (non-nucleated cells) are reacted with NHS.

54 e evolved to deliver bacterial proteins into nucleated cells, are found in many species of Gram-negat

55 which implicates nonclassical secretion from nucleated cells as the source of plasma FXIII-A.

56 ies of viable trophozoites against mammalian nucleated cells, as well as lysis of red blood cells, we

57 in vitro, as demonstrated by the presence of nucleated cells at the apical surface; the expression of

58 The bilateral trafficking of nucleated cells between the fetus and the mother was stu

59 s is the syndecans, present in virtually all nucleated cells, but with mostly unknown functions.

60 d reduce the rate of complement cytolysis of nucleated cells by 10-fold, and under some conditions by

61 l stromal cells led to an expansion of total nucleated cells by a median factor of 12.2 and of CD34+

62 eated cells and about 10-fold enhancement of nucleated cells by IL-3 during the initial 10 days.

63 ides for presentation at the surface of most nucleated cells by major histocompatibility complex clas

64 Given that all nucleated cells can respond to IFNgamma, the functional

65 Given that all nucleated cells can respond to IFNy, the functional cons

66 risk strata, age, gender, and the numbers of nucleated cells, CD3(+) T cells, CD34(+) hematopoietic c

67 Higher total nucleated cells, CD4+, CD8+, and CD14+ cell subset numbe

68 Circulating fetal nucleated cells (CFNCs) have shown potential in noninvas

69 Average recoveries (+/- 1 SD) of defrosted nucleated cells, colony-forming unit-granulocyte, -macro

70 ion of approximately 2 x 10(8)/kg unselected nucleated cells concomitant with the administration of h

71 red with recipients injected with unpurified nucleated cells containing the equivalent of 2- to 4-fol

72 Nucleated cells containing Y chromosomes were detected b

73 Retraction of the blood clot by nucleated cells contributes both to hemostasis and to ti

74 ear, and analysis revealed an elevated total nucleated cell count (136 x10(6)/L; reference range, 0-5

75 (including anticoagulant) was 103.1 mL; mean nucleated cell count was 8.9 x 10(8).

76 rrelations between cerebrospinal fluid (CSF) nucleated cell counts and elevated CSF protein levels an

77 Complete blood cell counts and SF nucleated cell counts were performed by the clinical hem

78 monocyte, lymphocyte, neutrophil, and total nucleated cell counts.

79 Most nucleated cells crawl about by extending a pseudopod tha

80 proteins expressed on human erythrocytes and nucleated cells differ with respect to acylation of an i

81 Though these nucleated cells do not remain viable after desiccation,

82 lobal CB inventory, and how to balance total nucleated cell dose and human leukocyte antigen match in

83 -American-British (FAB) subtypes M4-7, and a nucleated cell dose of > 2.42 x 10(8)/kg was associated

84 The patients received a median nucleated cell dose of 7.9 x 10(8)/kg and median C34(+)

85 0.0041), transplantation of units with total nucleated cell dose of more than 21 x 10(7) cells per kg

86 BMT, adverse cytogenetics, and low allograft nucleated cell dose were associated with inferior surviv

87 use of corticosteroids on day 100, and total nucleated cell dose were significant risk factors for cl

88 tatus, conditioning regimen intensity, total nucleated cell dose, and transplantation period was 79%

89 ity, donor alloimmunization, viral serology, nucleated cell dose, CD3(+) cell dose, and CD56(+) cell

90 tic cells originated when an ancestor of the nucleated cell engulfed bacterial endosymbionts that gra

91 a billion years ago when an ancestor of the nucleated cell engulfed two different prokaryotes in sep

92 age Young's elastic modulus was measured for nucleated cells, enucleated cells and nuclei (day 14) of

93 Multi-nucleated cells exist in all domains of life, ranging fr

94 All nucleated cells express major histocompatibility complex

95 es significantly improves clot retraction by nucleated cells expressing the integrin alpha(5)beta(1).

96 ting cardiac allografts display rare (<1% of nucleated cells/field), diffuse TUNEL+ cells, peaking on

97 pe I interferon (IFN) is synthesized by most nucleated cells following viral infection.

98 h an inertial focusing system to line up all nucleated cells for multi-stage magnetophoresis to remov

99 AX-FKHR can drive the generation of discrete nucleated cells from differentiated myofibers in vivo, a

100 synthetases appeared after the separation of nucleated cells from eubacteria.

101 After in vitro culture of blood mono-nucleated cells from grass-pollen-allergic subjects with

102 Relative functional abilities in 1 million nucleated cells from late fetal or newborn blood were se

103 c histologic changes, with relocalization of nucleated cells from red to white pulp regions.

104 ehicles for intracellular trafficking in all nucleated cells, from yeasts to humans.

105 All vertebrate nucleated cells generate peptides from their expressed g

106 The total number of nucleated cells harvested after expansion culture was sh

107 tive erythroid cells in mammals circulate as nucleated cells has led to the conjecture that they are

108 N-gammaR1 is constitutively expressed on all nucleated cells, IFN-gammaR2 membrane display is selecti

109 either HHV-6A or HHV-6B is present in every nucleated cell in the body.

110 ubiquitous parasitic protozoan that invades nucleated cells in a process thought to be in part due t

111 wide DNA methylation in umbilical cord blood nucleated cells in Project Viva, a prospective U.S.-base

112 alpha) is a pleomorphic cytokine produced by nucleated cells in response to viral infection.

113 generating the nuclear pool of NAD(+) in all nucleated cells in the body, and mounting evidence also

114 The mean number of donor-derived nucleated cells in the peripheral blood (PB) was 30%.

115 c protein kinases (ePKs) in the emergence of nucleated cells in the third superkingdom of life.

116 The presence of a relatively high number of nucleated cells in the umbilical-cord blood before it wa

117 trients, the ob/ob mice had only 60% as many nucleated cells in their marrow as controls.

118 acellular parasite Toxoplasma gondii infects nucleated cells in virtually all warm-blooded vertebrate

119 t gametocytes can fully develop inside these nucleated cells in vitro and in vivo, leading to infecti

120 tire leukapheresis product of over 6 billion nucleated cells, increasing CTC isolation capacity by tw

121 tion of lymphoblasts at a level of <1 in 106 nucleated cells, increasing sensitivity of ALL detection

122 ng an archetypical beta-PFT, can kill target nucleated cells independent of its pore-forming function

123 human embryonic and fetal RBCs, particularly nucleated cells, indicated that it would be sensible to

124 The median number of total nucleated cells infused was 3.4 x 10(7)/kg.

125 The median number of nucleated cells infused was 7.1 x 10(7)/kg (range, 1.7-2

126 tion correlated inversely with the number of nucleated cells infused.

127 ng host antimicrobial programs in nearly all nucleated cells interferons (IFNs) help orchestrate the

128 mation of transplanted wild-type bone marrow nucleated cells into lymphoid leukemia, and healthy mice

129 tion of enzymatic activity in G6PD-deficient nucleated cells is feasible through modulation of G6PD t

130 Cell doses ranged from 0.3 to 7.4 x 10(8) nucleated cells/kg (median, 3.0 x 10(8)cells/kg).

131 t two 4-6 HLA-identical UCBs with >3 x 10(7) nucleated cells/kg for the first and >1.5 x 10(7) for th

132 PBSC (> or = 7.5 x 10(8) nucleated cells/kg) were collected following priming wit

133 cell dose for the UCB graft was 3.0 x 10(7) nucleated cells/kg, resulting in the selection of a seco

134 host cells to fuse together into large multi-nucleated cells known as syncytia.

135 The subsequent observation of nucleated cells led to the identification of individual

136 With the exception of eosinophils, all nucleated cell lineages studied were similarly affected

137 firmed the presence of these mRNA species in nucleated cells lining the neovessels.

138 In platelets or nucleated cells, loss of kindlins markedly reduces alpha

139 It induces apoptosis in the target nucleated cells, mechanistic details of which are still

140 When 10(6) fetal blood nucleated cells (median gestational age, 10(+2) weeks [1

141 gher plasma cell infiltration (percentage of nucleated cells: median, 60% [interquartile range {IQR},

142 x 10(5) versus 2.84 x 10(5) +/- 0.28 x 10(5) nucleated cells/ml; p = 0.021), and injury score (7.0 +/

143 ) provide new insight into nucleated vs. non-nucleated cell models and their ability to match experim

144 Acceptance criteria of >10 nucleated cells/mul in the CSF of immunocompetent adults

145 The acceptance criteria of >10 nucleated cells/mul in the CSF of immunocompetent subjec

146 UCB units (median infused dose, 3.5 x 10(7) nucleated cell [NC]/kg; range, 1.1-6.3 x 10(7) NC/kg) af

147 dian number of therapeutic vector copies per nucleated cell of patient BM and PB at the second year p

148 f at least 0.1 therapeutic vector copies per nucleated cell of patient bone marrow (BM) or PB at the

149 arrow cells nor circulating peripheral blood nucleated cells of donor or recipient mice had any detec

150 rotein tyrosine phosphatase expressed by all nucleated cells of hematopoietic origin.

151 agments permeabilize the plasma membranes of nucleated cells of rodent, dog, monkey, and human origin

152 n in endothelial cells and potentially other nucleated cells of the body.

153 nts in cohorts B and D received 25% of their nucleated cells on day -2 and 75% on day 0 (split reinfu

154 Specific capture of nucleated cells or cells expressing epithelial cell adhe

155 M MPC did not result in increased numbers of nucleated cells or MPC in BM or spleens of CCR2 (-/-) mi

156 fusion of 150 x 10(6) autologous BMCs (total nucleated cells) or placebo (BMC:placebo, 2:1) was perfo

157 Cell dose exceeded 1.5 x 10(7) nucleated cells per kilogram for 90% of banked units.

158 tients received a median of 8.34x10(7) total nucleated cells per kilogram of body weight and 1.81x10(

159 se of 3.7 x 107 (range, 1.6 x 107-6.0 x 107) nucleated cells per kilogram of recipient body weight (N

160 ween neutrophil and platelet engraftment and nucleated cells per kilogram, CD34(+) cells per kilogram

161 mproved by transplanting more than 3 x 10(8) nucleated cells per kilogram.

162 < .005) but not with CFU-GM per kilogram or nucleated cells per kilogram.

163 und the large cardiac arteries (about 20% of nucleated cells/periarterial field).

164 lasminogen altered thrombus mass or thrombus nucleated cell, platelet, or fibrin(ogen) content at 24

165 ne, the red blood cell, with that of several nucleated cells possessing an abundant endomembrane comp

166 ed, including CTP prevalence (CTPs per 10(6) nucleated cells), proliferation by colony forming unit (

167 In nucleated cells protein 4.1 is not associated exclusivel

168 billions of base pairs of genomic DNA in all nucleated cells raises the question of how cGAS is not c

169 cted PBSC on day -2 (median, 2.26 x 10(8)/kg nucleated cells [range, 1.7 to 3.3 x 10(8)/kg]) with the

170 During cell death and aberrant mitosis, nucleated cells release DNA, resulting in "cell-free" DN

171 more in DBA/2 mice, although percentages of nucleated cells remained the same in both strains.

172 Nucleated cells resist MAC-mediated cytolysis by express

173 nor bone marrow (2.7x10(8) and 3.8x10(8) /kg nucleated cells, respectively) obtained from a human leu

174 In analogy to apoptosis of nucleated cells, suicidal erythrocyte death called erypt

175 b)beta(3) activation in a non-hematopoietic, nucleated cell system have been unsuccessful.

176 he presence of mitochondria in virtually all nucleated cells, the destruction in PBC is limited to sm

177 hy donors, CD34+ HPCs accounted for 0.05% of nucleated cells; their numbers were strictly age depende

178 the H-2T18d gene product on essentially all nucleated cells through the control of a heterologous H-

179 Both total nucleated cell (TNC) dose and human leukocyte antigen (H

180 speed and survival are related to the total nucleated cell (TNC) dose of the graft.

181 The median precryopreservation total nucleated cell (TNC) dose was 5.1 x 10(7) TNC/kg (range,

182 In contrast, total nucleated cell (TNC), CD34(+) cell, and colony-forming c

183 ive conditioning, higher dominant unit total nucleated cell (TNC), CD34(+) cell, and colony-forming u

184 ed a 10-fold increase in the number of total nucleated cells (TNC) (20-30 x 10(10) TNC) compared to b

185 ts containing a minimum of 2.5 x 10(7) total nucleated cells (TNC)/kilogram patient body weight are f

186 This is considered from total nucleated cells (TNCs), unless there is erythroid-hyperp

187 Here we show that PAX7-FKHR causes nucleated cells to form and separate from syncytial myof

188 HC molecules are expressed at the surface of nucleated cells to present peptides to T cells.

189 common mechanism used by different types of nucleated cells to release their vesicular contents.

190 us regeneration after allogeneic bone marrow nucleated cell transplantation but also exhibited improv

191 xoplasma gondii is able to infect nearly all nucleated cell types of warm-blooded animals.

192 ineate damaged volumes in vivo nor image non-nucleated cell types or compartments).

193 capacity to lyse erythrocytes and a range of nucleated cell types.

194 s a potential positive feedback mechanism in nucleated cell types.

195 Erythrocytes may, similar to apoptosis of nucleated cells, undergo eryptosis, characterized by cel

196 activation processes to events occurring in nucleated cells undergoing apoptosis suggests a possible

197 Although well studied in nucleated cells, UPR in absence of transcriptional regul

198 Median number of collected total nucleated cells was 4.4 x 10(7)/kg.

199 d blood were thawed and the purity of viable nucleated cells was increased from 65% to over 94% with

200 Cytotoxicity to erythrocytes and nucleated cells was moderate.

201 , up to a 13-fold reduced expansion of total nucleated cells was observed in response to cocktails co

202 Virus bound to nucleated cells was significantly more infectious than v

203 idual disease (MRD)-negative status (<10(-5) nucleated cells) was confirmed in 33 patients, represent

204 ociated microtubule arrays within individual nucleated cells, we show that both define the cell centr

205 Median-infused total nucleated cells were 2.5x10/kg for IB-UCBT and 3.9x10/kg

206 Unsorted marrow nucleated cells were assessed for chimerism using VNTR p

207 mas, we showed that 0.14% to 1.6% of CD45(-) nucleated cells were EPCs that coexpressed CD133 and the

208 entage in DBA/2 mice, and more tri- and quad-nucleated cells were in C57BL/6 mice.

209 onsistent with the increased formation of bi-nucleated cells, which result from perturbations of the

210 trusion, generating reticulocytes and small, nucleated cells with a thin rim of cytoplasm ("pyrenocyt

211 ave extant archaeprotist descendants: motile nucleated cells with Embden-Meyerhof glycolysis and subs

212 Multi-nucleated cells with unevenly distributed nuclei reveal

213 sufficient to induce the formation of multi-nucleated cells, with an average of 10% of all cells for

214 nctional thickening, dense dermal nests, and nucleated cells within papillary dermis, were more frequ