ライフサイエンスコーパス: nucleolar protein

1 horylates and activates UBF1, an exclusively nucleolar protein.

2 ly identified, non-essential, RRM-containing nucleolar protein.

3 it, like Nopp140, is a highly phosphorylated nucleolar protein.

4 ates that the protein involved in TCOF1 is a nucleolar protein.

5 tions which lead to aberrant expression of a nucleolar protein.

6 the first direct evidence that treacle is a nucleolar protein.

7 The human protein C23 (nucleolin) is a major nucleolar protein.

8 ry through its association with Net1/Cfi1, a nucleolar protein.

9 it colocalized with nucleolin, a predominant nucleolar protein.

10 response previously observed in a subset of nucleolar proteins.

11 ons of functional similarities between these nucleolar proteins.

12 gation has identified NuMA among hundreds of nucleolar proteins.

13 ration in a subnuclear fraction enriched for nucleolar proteins.

14 olar biology involving the reorganization of nucleolar proteins.

15 o acids as shown by Western blotting of HeLa nucleolar proteins.

16 at Nopp52 is a member of a family of related nucleolar proteins.

17 d by E-rich regions, as defining features of nucleolar proteins.

18 out apparently affecting the levels of other nucleolar proteins.

19 One such TOP-containing mRNA codes for novel nucleolar protein 1 (Non1), a conserved p53 destabilizin

20 Here, we report that deletion of Nol3 (Nucleolar protein 3) in mice leads to an MPN resembling

21 thylight assays for two corresponding genes, nucleolar protein 4 (NOL4), and lipoma HMGIC fusion part

22 lyze expression and localization of BOP1 and nucleolar protein 56 in human tissue samples from variou

23 ear antigen (MINA53; also known as MINA) and nucleolar protein 66 (NO66) catalyse histidine hydroxyla

24 f mice with CKD have increased expression of nucleolar protein 66 (NO66), as do muscle biopsy specime

25 Previous studies showed that nucleolar protein 66 (NO66), the Jumonji C-domain-contai

26 aryotic-like domains, here we identify NopA (nucleolar protein A), which displays four regulator of c

27 s demonstrate that MEQ is both a nuclear and nucleolar protein, adding MEQ to the growing list of tra

28 137 degradation, including redistribution of nucleolar proteins, altered nucleolar morphology, and re

29 B23 (NPM/nucleophosmin) is a multifunctional nucleolar protein and a member of the nucleoplasmin supe

30 Protein B23 is an abundant nucleolar protein and a putative ribosome assembly facto

31 e III (Pol III)-mediated transcription, is a nucleolar protein and modulates Pol I-mediated transcrip

32 EXOSC8 silence decreases nucleolar protein and proliferation marker levels, as we

33 Protein B23 is a major nonribosomal nucleolar protein and putative ribosome assembly factor

34 Here we identify human JHDM1B as a nucleolar protein and show that JHDM1B preferentially bi

35 ide binding protein-like 3-like (GNL3L) is a nucleolar protein and the vertebrate paralogue of nucleo

36 lacked significant autoproteolysis, but many nucleolar proteins and autoantigens were degraded by C1

37 monstrate that Utp23 and Utp24 are essential nucleolar proteins and previously undescribed components

38 on of p150 causes redistribution of multiple nucleolar proteins and reduces nucleolar association wit

39 al increase (up to 40%) in concentrations of nucleolar proteins and RNA, most likely due to cell shri

40 ntial interactions and relationships between nucleolar proteins and thereby suggests putative functio

41 The precise localization of most nucleolar proteins and whether their specific localizati

42 with p50 in a cellular fraction enriched in nucleolar proteins, and this immunocomplex also includes

43 ither topoisomerase I (anti-topo I; n = 12), nucleolar protein (ANoA; n = 12), or centromeric protein

44 Many nucleolar proteins appear to concentrate within the bord

45 in the relative levels of approximately 500 nucleolar proteins are compared at different timepoints

46 We show that the localization preferences of nucleolar proteins are determined by their IDRs and the

47 Therefore, how these nucleolar proteins are functionally coordinated with ste

48 vel virus-induced mechanism by which certain nucleolar proteins are selectively redistributed in infe

49 also interacts with a set of EBP1-associated nucleolar proteins as well as factors that function in p

50 uman RNP complexes that contain nonribosomal nucleolar proteins, as well as ribosomal proteins and rR

51 proteins, an unknown number of nonribosomal nucleolar proteins, as well as small nucleolar RNA-ribon

52 quantitative dynamics by which six different nucleolar proteins assemble into the nucleoli of Drosoph

53 included members of the cohesin complex and nucleolar proteins associated with rDNA biology.

54 with the two-hybrid system which identified nucleolar protein B23 (nucleophosmin) as being associate

55 identified the abundant and multifunctional nucleolar protein B23 as a potential target of FRGY2a an

56 age disrupts the interaction of ARF with the nucleolar protein B23(nucleophosmin) and promotes a tran

57 been shown to interact functionally with the nucleolar protein B23/NPM (B23) and inhibit rRNA biogene

58 tion to nucleolin, the previously identified nucleolar proteins B23 and fibrillarin, proteins with el

59 (siRNA) approach, we then evaluated whether nucleolar proteins B23/nucleophosmin and nucleolin, prev

60 nucleostemin interacts with nucleophosmin, a nucleolar protein believed to possess oncogenic potentia

61 The p19(Arf) tumor suppressor, a nucleolar protein, binds to Mdm2 to induce p53-dependent

62 The nucleolar protein block of proliferation 1 (BOP1) is ass

63 We have recently shown that the mammalian nucleolar protein Bop1 is involved in synthesis of the 2

64 show that Pes1 physically interacts with the nucleolar protein Bop1, and both proteins direct common

65 sis checkpoint defect, we identified a novel nucleolar protein called Dnt1 and other nucleolar protei

66 n components of H/ACA snoRNPs, the essential nucleolar protein Cbf5p is the most likely pseudouridine

67 e leverage the ability of Vpr to deplete the nucleolar protein CCDC137 to understand how Vpr-induced

68 imaging the rapid kinetics of motile cilia, nucleolar protein condensation during light-sensitive mi

69 tion in an RNA recognition motif of RBM28, a nucleolar protein conserved to yeast (Nop4).

70 D/E tracts of nucleolar proteins contribute to lowering the pH of co-c

71 The Arabidopsis Nucleolar Protein Database provides information on 217 p

72 In addition, B23/nucleophosmin, another nucleolar protein, did not interact with the cadmium res

73 mations, indicating changes in the subset of nucleolar proteins during cell reprogramming.

74 r with photobleaching experiments to measure nucleolar protein dynamics in anaphase, consolidate a mo

75 e analyzed the effect of p14ARF induction on nucleolar protein dynamics using SILAC mass spectrometry

76 a gene expression, RNA polymerase II, a host nucleolar protein (EAP or L22) known to be associated wi

77 domains of EBNA1 associates with a cellular nucleolar protein, EBP2, and it has been proposed that t

78 Dyskerin is a nucleolar protein encoded by the DKC1 gene that (i) stab

79 Nucleostemin (NS) is a nucleolar protein expressed in adult and embryo-derived

80 We observed that the nucleolar protein fibrillarin began to redistribute by 6

81 rcury chloride induces autoantibodies to the nucleolar protein fibrillarin in H-2s, but not in H-2b,

82 pitation experiments revealed that the major nucleolar protein fibrillarin is coprecipitated in the P

83 ression of rRNA, ribosomal proteins, and the nucleolar protein fibrillarin, dependent on NCL-1.

84 al transcription and cell cycle factors, the nucleolar proteins fibrillarin (Fb) and Nopp140 (Nopp),

85 odies was normal with antibodies against two nucleolar proteins, fibrillarin and nucleolin.

86 Nucleophosmin (NPM1), a nucleolar protein frequently mutated in hematopoietic ma

87 ScNpl3 with RG-rich domains of S. cerevisiae nucleolar proteins, Gar1 and Nop1 (ScGar1, ScNop1), or o

88 epeats within endogenous NUCL-1 and a second nucleolar protein, GARR-1 (GAR1), demonstrates these dom

89 ion, and functional significance of specific nucleolar proteins have not been investigated thoroughly

90 Nucleolin is a major nucleolar protein implicated in many aspects of ribosoma

91 C1, an abundant and evolutionarily conserved nucleolar protein in eukaryotic organisms, is required f

92 evealed an association of RAG1 with numerous nucleolar proteins in a manner dependent on amino acids

93 er investigation into the functional role of nucleolar proteins in advanced CaP.

94 d with nucleolar fibrillarin and other known nucleolar proteins in interphase cells but was not detec

95 degron system can be used to rapidly deplete nucleolar proteins in mammalian cells, that PAF53 is nec

96 smic concentration and distribution of these nucleolar proteins in the wild-type embryos is consisten

97 ta also suggest an underappreciated role for nucleolar proteins in transcriptional regulation.

98 ect ribosome biogenesis by modifying certain nucleolar proteins in yeast.

99 functional clusters: ribosomal subunits and nucleolar proteins including the DEAD box helicases, DHX

100 P depletion induced a rapid translocation of nucleolar proteins, including nucleostemin and nucleolin

101 ovel nucleolar protein called Dnt1 and other nucleolar proteins, including Rrn5 and Nuc1, which are k

102 We here show that it causes many yeast nucleolar proteins, including the fibrillarin homolog No

103 GID4 interactors are enriched for nucleolar proteins, including the Pro/N-degron-containin

104 stribution of small nucleolar RNA-associated nucleolar proteins independently of their effect on nucl

105 Nucleolar protein interacting with the FHA domain of pKi

106 partial sequences identical to annexin XI-A, nucleolar protein interacting with the forkhead-associat

107 Nucleophosmin/B23 (NPM) is a pleiotropic nucleolar protein involved in a variety of cellular proc

108 Nucleolin is an abundant 70 kDa nucleolar protein involved in many aspects of ribosomal

109 We found that nucleolin, a nucleolar protein involved in ribosomal maturation, boun

110 at ARF interacts with B23, a multifunctional nucleolar protein involved in ribosome biogenesis, and p

111 Nucleophosmin 1 (NPM1) is a nucleolar protein involved in ribosome biogenesis, stres

112 Bop1 is a conserved nucleolar protein involved in rRNA processing and riboso

113 Bop1 is a novel nucleolar protein involved in rRNA processing and riboso

114 Nucleostemin (NS) is a nucleolar protein involved in the regulation of cell pro

115 encode a highly-conserved eukaryotic set of nucleolar proteins involved in rRNA transcription, assem

116 Nucleophosmin (NPM), a predominantly nucleolar protein, is also critical in ribosome biogenes

117 Nucleomethylin (NML), a novel nucleolar protein, is important for mediating the assemb

118 that demonstrate the requirement of a novel, nucleolar protein, LLP (LAPS18-like protein), for the fo

119 dition, for one-third of the 217 Arabidopsis nucleolar proteins, localization images are available fr

120 Here, we show that a nucleolar protein, modulo, a homolog of nucleolin, media

121 Here we identify the nucleolar protein, Modulo, in complex with CAL1, a facto

122 ucleolar and is highly homologous to the rat nucleolar protein NAP57, which coimmunoprecipitates with

123 y identified strong homology between the rat nucleolar protein Nap57p, its yeast homolog Cbf5p, and t

124 The highly conserved eukaryotic nucleolar protein Nep1 has an essential but unknown func

125 nucleolus for most of the cell cycle by the nucleolar protein Net1 and is released into the nucleus

126 dc14 by counteracting phosphorylation of the nucleolar protein Net1 by Cdk.

127 Hog1 phosphorylates the nucleolar protein Net1, altering its affinity for the ph

128 e determined that HRad17 can interact with a nucleolar protein, NHP2L1.

129 a TIGR-associated (Tas) protein containing a nucleolar protein (Nop) domain, sometimes fused to HNH (

130 les of nop2 led to the identification of the nucleolar proteins Nop12p and Nop13p in Saccharomyces ce

131 sical interaction with a newly characterized nucleolar protein, Nop14.

132 Depletion of Nop5p caused the nucleolar protein Nop1p (yeast fibrillarin) to be locali

133 To investigate the function of the nucleolar protein Nop2p in Saccharomyces cerevisiae, we

134 The nucleolar protein Nop2p is an essential gene product tha

135 The Saccharomyces cerevisiae nucleolar protein Nop4p is necessary for processing of r

136 MARBP-1 and MARBP-2 are homologous to yeast nucleolar proteins Nop56p and Nop58p, which are involved

137 We have identified a novel nucleolar protein, Nop5p, that is essential for growth i

138 yeast preribosomal particles containing the nucleolar protein Nop7p and developed means to separate

139 ne S-transferase fusion proteins of CK2, the nucleolar protein Nopp140 was identified as a CK2-associ

140 pression of the central repeat domain of the nucleolar protein Nopp140.

141 Targeting the killswitch to the nucleolar protein NPM1 altered nucleolar composition and

142 factors RBM8A, SRSF9, and PSF as well as the nucleolar proteins NPM1 and PHF6, and recombinant GSK-3b

143 ant cytoplasmic translocation of the encoded nucleolar protein (NPM1c(+)).

144 We report that the abundant nucleolar protein nucleolin accelerates nucleic acid ann

145 n of UL84FLAG also colocalized with the host nucleolar protein nucleolin at the peripheries of both r

146 viral proteins, viral DNA, and the cellular nucleolar protein nucleolin in the subnuclear replicatio

147 83% homologous with the previously sequenced nucleolar protein nucleolin.

148 to MYC's effects on cell growth include the nucleolar proteins nucleolin and fibrillarin, as well as

149 f nucleoli with C1 caused degradation of the nucleolar proteins nucleolin and nucleophosmin 1.

150 a direct interaction between CRYBB2 and the nucleolar protein, nucleolin.

151 ligomerization domain of the multifunctional nucleolar protein nucleophosmin (Npm-N) are central to i

152 e liquid-like nucleoli, co-localize with the nucleolar protein nucleophosmin (NPM1), and alter the ph

153 rrent with the initial redistribution of the nucleolar protein nucleophosmin (NPM1).

154 ine-arginine nucleolar localization, perturb nucleolar protein nucleophosmin 1 and suppress nascent p

155 We show that CTCF copurifies with the nucleolar protein nucleophosmin and both are present at

156 oma (ALCL), results in the production of the nucleolar protein nucleophosmin-anaplastic lymphoma kina

157 In contrast, the nucleolar protein nucleophosmin/B23, which binds to p19A

158 Studies presented here indicate that the nucleolar protein, nucleophosmin (NPM), redistributes fr

159 an effect that does not occur with two other nucleolar proteins, nucleophosmin or nucleolin.

160 oup previously demonstrated induction of the nucleolar protein nucleostemin (NS) in response to cardi

161 The nucleolar protein nucleostemin (NS) is essential for cel

162 Nucleolin is a major nucleolar protein of exponentially growing eukaryotic ce

163 protease activation and the cleavage of many nucleolar proteins or autoantigens.

164 ntinuclear autoimmunity by broadly degrading nucleolar proteins or autoantigens.

165 In addition, nucleolar protein p120 was also found to be co-immunopre

166 can be replaced by an RNA binding motif from nucleolar protein p120 without a deleterious effect on i

167 logy with the human proliferation associated nucleolar protein p120.

168 ents of the pachytene checkpoint include the nucleolar protein Pch2 and the heterochromatin component

169 t with their in vivo immiscibility, purified nucleolar proteins phase separate into droplets containi

170 of LIN28A contribute to LIN28A and the other nucleolar proteins' phase-separated condensate establish

171 The nucleolar protein PICT1 regulates tumor suppressor p53 b

172 Here we find that nucleolin (NCL), a major nucleolar protein, posttranscriptionally regulates the e

173 lar disruption also causes redistribution of nucleolar proteins, potentially altering their interacti

174 ations in the DKC1 gene encoding dyskerin, a nucleolar protein predicted to be involved in rRNA proce

175 Specifically, nucleolin, an essential nucleolar protein, preferentially binds the HRE G-quadru

176 Dyskerin is a nucleolar protein present in small nucleolar ribonucleop

177 Srp40p is a nonessential yeast nucleolar protein proposed to function as a chaperone fo

178 t, nuclear poly-GA was more toxic, impairing nucleolar protein quality control and protein biosynthes

179 Midnolin has been to date classified as a nucleolar protein regulating mouse development.

180 Nucleostemin (NS) is a nucleolar protein regulating stem cell proliferation and

181 LAS1L was first described as a nucleolar protein required for maturation of the 60S pre

182 Thus, Nop12p is a novel nucleolar protein required for pre-25S rRNA processing a

183 ino acid sequence homology to yeast Nop5p, a nucleolar protein required for pre-rRNA processing and r

184 entify Las1L as a previously uncharacterized nucleolar protein required for ribosome biogenesis.

185 NPM1 is a nucleolar protein required for the maintenance of genome

186 termined that the DEAD box helicase Has1p, a nucleolar protein required for the production of 18S rRN

187 We recently showed that down-regulation of nucleolar protein RNA helicase II/Gualpha (RH-II/Gualpha

188 f K-rich LCR copy number for assembly of the nucleolar protein RPA43 in vivo and in vitro.

189 We now identify a nucleolar protein, RRP1B, as an E2F1-specific transcript

190 In the absence of rDNA, the nucleolar proteins studied are able to form high-concent

191 We show that Fob1p is a nucleolar protein, suggesting a direct involvement in th

192 The ARF tumor suppressor is a nucleolar protein that activates p53-dependent checkpoin

193 We show that DHX33 is a cell cycle-regulated nucleolar protein that associates with ribosomal DNA (rD

194 e we demonstrate a unique role for FLNA as a nucleolar protein that associates with the RNA polymeras

195 ied as a stem cell- and cancer cell-enriched nucleolar protein that controls the proliferation of the

196 hy ribosome biogenesis 1 (URB1) is a static, nucleolar protein that ensures 3' end pre-rRNA anchoring

197 us fumigatus CgrA is the ortholog of a yeast nucleolar protein that functions in ribosome synthesis.

198 We show that SIRT7 is a widely expressed nucleolar protein that is associated with active rRNA ge

199 teracts with fibrillarin, a highly conserved nucleolar protein that is associated with all Box C/D sm

200 The affected protein, dyskerin, is a nucleolar protein that is found associated with the H/AC

201 encodes a conserved Saccharomyces cerevisiae nucleolar protein that is required for 60S subunit bioge

202 s of the upstream binding factor 1 (UBF1), a nucleolar protein that participates in the regulation of

203 Here, we report that ZNF668 is a nucleolar protein that physically interacts with and reg

204 In this report, we show that Rlp7p is a nucleolar protein that plays a critical role in processi

205 ion between the DDR factor NBS1 and TCOF1, a nucleolar protein that regulates ribosomal DNA (rDNA) tr

206 We report that Nucleolin (Ncl), a nucleolar protein that regulates rRNA synthesis and ribo

207 Furthermore, we show that FGF13 1A is a nucleolar protein that represses ribosomal RNA transcrip

208 RNA helicase II/Gu (RH II/Gu) is a nucleolar protein that unwinds dsRNA in a 5' to 3' direc

209 lyadenylation factors, small nucleolar RNAs, nucleolar proteins that are probably involved in pre-rRN

210 This work shows that in contrast to most nucleolar proteins that negatively control MDM2, GNL3L a

211 uenced by the phase separation properties of nucleolar proteins, the presence of RNA, protein modific

212 NPM1) causes relocalization of this normally nucleolar protein to the cytoplasm (NPM1c+).

213 s undergoes sequential disassembly releasing nucleolar proteins to the cytoplasm as nucleoli concomit

214 tly relocated many, but not all, nuclear and nucleolar proteins to the cytoplasm.

215 In dividing wild-type cells, segregation of nucleolar proteins to the daughter nuclei occurs after s

216 These included ribosomal proteins, nucleolar proteins, translation initiation factors, heli

217 sponse; it interacts with the low-complexity nucleolar protein Treacle (also referred to as TCOF1) an

218 We investigated the role of the nucleolar protein Treacle in organizing and regulating t

219 Here we screened 200 candidate nucleolar proteins using high-resolution live-cell micro

220 A cDNA encoding a nucleolar protein was selected from a pea (Pisum sativum

221 Co-localization with nucleolar proteins was verified by confocal immunofluore

222 For nucleophosmin 1 (NPM1), an essential nucleolar protein, we show that phosphorylation of S254

223 oantigens were degraded by C1 proteases; >20 nucleolar proteins were identified as C1 cleavable.

224 After C1 treatment, cleaved nucleolar proteins were identified by proteomic two-dime

225 ore, in embryos lacking ribosomal RNA genes, nucleolar proteins were redistributed into new bodies or

226 NPM (nucleophosmin/B23) is a major nucleolar protein which is 20 times more abundant in tum

227 Nucleolin is an abundant nucleolar protein which is believed to play a role in rD

228 Protein p120 is a proliferation-related nucleolar protein which is detectable early in the G1 ph

229 ifically recognized an approximately 100 kDa nucleolar protein, which we referred to as the 'Gu' prot

230 Eight of these genes encode nucleolar proteins, which are implicated in ribosome bio

231 Protein B23 is a multifunctional nucleolar protein whose cellular location and characteri

232 Protein B23 is a multifunctional nucleolar protein whose molecular chaperone activity is

233 l counting analysis quantitated 135 specific nucleolar proteins whose levels were significantly alter

234 Nucleostemin is a nucleolar protein widely expressed in proliferating cell

235 P. falciparum calpain is a unique nucleolar protein with an interesting mechanism of targe

236 In this study, we identify NOM1 (nucleolar protein with MIF4G domain 1) as a PP1-interact

237 a novel MIF4G/MA3 family member called NOM1 (nucleolar protein with MIF4G domain 1) that was identifi

238 y is important during CMV infection with the nucleolar protein, with nucleolin playing a role in main

239 eral orders of magnitude slower than that of nucleolar proteins, with rRNA steadily moving away from

240 The essential, conserved yeast nucleolar protein Ytm1 is one of 17 proteins in ribosome

241 In this study, we demonstrated that the nucleolar protein ZNF692 directly interacts with nucleop