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1 y, although slower diffusion was observed in nucleoli.
2 in vitro exhibit smaller and more elongated nucleoli.
3 distribution of MageB2 protein includes the nucleoli.
4 reduces alpha-satellite DNA association with nucleoli.
5 sed in mammalian cells, these variants bound nucleoli.
6 lear membrane; they exhibited small punctate nucleoli.
7 pheries of both replication compartments and nucleoli.
8 ting its translocation from nucleoplasm into nucleoli.
9 of MDM2 and translocation of DeltaNp63 into nucleoli.
10 ould not confirm localization of midnolin in nucleoli.
11 meric clusters, chromosomal territory 3, and nucleoli.
12 d in specific, robust accumulation of Gag in nucleoli.
13 , and lipids in the molecular composition of nucleoli.
14 NA-containing NORs that are dissociated from nucleoli.
15 ing occur in regions of the nucleus known as nucleoli.
16 mordia, and its protein was localized to the nucleoli.
17 eudosubstrate that directly recruits Fbw7 to nucleoli.
18 y to pericentric heterochromatin-surrounding nucleoli.
19 istributed throughout nuclei and enriched in nucleoli.
20 in large nuclear aggregates that often ring nucleoli.
21 sors, and fibrillarin does not accumulate in nucleoli.
22 repeats of rDNA coding sequences within the nucleoli.
23 bserved accumulation of SUMO proteins within nucleoli.
24 e only phosphorylation site, retains FEN1 in nucleoli.
25 es in late mitosis before the reformation of nucleoli.
26 Pes1 was typically restricted to nuclei and nucleoli.
27 e with its targeting and localization to the nucleoli.
28 o a lesser extent PP1beta concentrate in the nucleoli.
29 endogenous proteins appear within mammalian nucleoli.
30 ther lack an organized nucleolus or have two nucleoli.
31 yield mature H/ACA RNPs in Cajal bodies and nucleoli.
32 s but also necessary for localizing ADAR2 to nucleoli.
33 also observed miR-206 to be concentrated in nucleoli.
34 calization of the marker protein, coilin, to nucleoli.
35 id not localize bulk sumoylated molecules to nucleoli.
36 plicing positioned at varying distances from nucleoli.
37 asmic locations, Lsm proteins are present in nucleoli.
38 ver, La lacking the SBM does not localize to nucleoli.
39 rotein nucleostemin, and enlarged, malformed nucleoli.
40 ha-actinin and exhibited a nucleus with many nucleoli.
41 n the cytosol and in other cells also in the nucleoli.
42 RNp and p97/VCP physically interacted in the nucleoli.
43 t IFI16 was localized in the nucleoplasm and nucleoli.
44 pair in human cells colocalize with Mus81 in nucleoli.
45 lization of RGS6 proteins from such sites to nucleoli.
46 encing of chromatin associated with purified nucleoli.
47 ormation of membrane-less organelles such as nucleoli.
48 nucleolar R-loops recruited RNase H1 to the nucleoli.
49 ion coupled with exercise also display small nucleoli.
50 vitro and for localization within mammalian nucleoli.
51 ssociation of Pol III-transcribed genes with nucleoli.
52 ~60% of which were detected in the H1 mutant nucleoli.
55 alized to distinct nuclear bodies, including nucleoli (148), promyelocytic leukemia nuclear bodies (3
56 h a single nucleolus and those with multiple nucleoli; (2) the percentage of each phenotype is sex sp
57 ndent sequestration of the telomerase RNA in nucleoli, a process that excludes telomerase from DNA re
59 olar stress and establish the postulate that nucleoli acts as sensors of stress, regulating the cellu
62 increased protein synthesis, and report that nucleoli also expand as aging progresses in cells derive
63 logical features, such as prominent/abundant nucleoli and a colony with a tightly packed appearance a
64 er cells depleted of NPM1 displayed deformed nucleoli and a striking rearrangement of perinucleolar h
65 luorescence that ubiquitin is present within nucleoli and also demonstrate by immunoprecipitation tha
66 regulatory events are directly regulated by nucleoli and are dependent on intact nucleolar structure
68 s associate with the fibrillar components of nucleoli and bind pre-rRNA during transcription, trigger
69 BEN domain-containing protein, localizes in nucleoli and binds to ribosomal RNA gene promoters to he
71 plex associations of both hTR and hTERT with nucleoli and Cajal bodies during S phase, implicating bo
72 is a nuclear protein localized primarily in nucleoli and Cajal bodies that was identified as a downs
75 e report that mammalian RNase H1 enriches in nucleoli and co-localizes with R-loops in cultured human
76 a-irradiation or mitomycin C, WRN leaves the nucleoli and co-localizes with the Mre11 complex in the
78 at RBS was associated with highly fragmented nucleoli and defects in both ribosome biogenesis and pro
80 is is elevated as a consequence of activated nucleoli and enhanced ribosome biogenesis in HGPS-derive
81 uded the following: (1) increased numbers of nucleoli and enlarged nuclei, (2) narrower spaces betwee
82 In cells, poly(PR) DPRs disperse NPM1 from nucleoli and entrap rRNA in static condensates in a DPR-
83 d insulin-like-peptide mutants exhibit small nucleoli and fibrillarin expression, as do long-lived di
84 protein colocalized with fibrillarin in the nucleoli and formed punctate structures associated with
86 nocarcinomas, leads to formation of enlarged nucleoli and increased nucleolar number in prostate lumi
87 cells from patients with HGPS have expanded nucleoli and increased protein synthesis, and report tha
88 stinfection, UXP is strongly associated with nucleoli and is found throughout the nucleus; later, UXP
90 an emerging body of evidence suggesting that nucleoli and NF-kappaB signalling converge at multiple l
92 ouble-labeling showed colocalization in both nucleoli and nucleoplasmic foci in breast tumor cells an
93 of MCF7 cells, BRCA1 protein dispersed from nucleoli and nucleoplasmic foci to other nucleoplasmic s
97 s dominate endogenous LLPS, and give rise to nucleoli and other condensates that do not exhibit a fix
99 tury from both animal and plant cells, human nucleoli and particularly the five human nucleolus organ
101 tes DDX21, an RNA helicase that localizes to nucleoli and promotes rDNA transcription when ADP-ribosy
102 the cytoplasm and nucleus, concentrating in nucleoli and relocalizing to the nucleoplasm in response
103 found localization of UL84 with nucleolin in nucleoli and showed that the presence of nucleolin is in
104 umerous genomic regions with nuclear lamina, nucleoli and surface of chromosomes in the same, single
105 protein chaperone that shuttles between the nucleoli and the cytoplasm and has been associated with
109 h binds to Mdm2 and NPM but is excluded from nucleoli and the other of which enters nucleoli but is h
110 stores, and protects ribosomal protein S9 in nucleoli and therefore could facilitate ribosome biogene
111 ng viral replication and its localization to nucleoli and viral replication centers provide further i
115 ng distinct longevity pathways exhibit small nucleoli, and decreased expression of rRNA, ribosomal pr
116 omatically identify lipid droplets, nucleus, nucleoli, and endoplasmic reticulum in datasets that are
118 , and mitochondria-rich cytoplasm, prominent nucleoli, and markers of hepatocytes and cholangiocytes.
120 lear organelles, such as Cajal bodies (CBs), nucleoli, and other nuclear bodies, is dynamic and can c
121 granular components, respectively, in active nucleoli, and partition separately into the two componen
122 ntered cells, migrated to the nucleus, bound nucleoli, and poisoned RNA biogenesis, which caused cell
123 eome, enzymatically active PP1 is present in nucleoli, and PP1gamma is highly concentrated in nucleol
125 upstream binding factor UBF-1 at interphase nucleoli, and this interaction is epigenetically retaine
131 egrity and organization of repeated DNAs and nucleoli are regulated by the H3K9 methylation and RNAi
133 autoantibodies, which frequently target the nucleoli, are pathogenic hallmarks of systemic lupus ery
135 used by steps in p53 regulation occurring in nucleoli, as suggested by some biochemical evidence.
136 [U4/U6.U5] tri-snRNP localize transiently to nucleoli, as visualized by microscopy after injection of
137 ion factor UBF1, and undergo transition into nucleoli at sites of rRNA synthesis during interphase.
138 hey have rounded cell bodies, have prominent nucleoli, attach poorly to the culture dish, and are sen
140 from nucleoli and the other of which enters nucleoli but is handicapped in binding to Mdm2 and NPM,
142 s, identify disease-associated disruption of nucleoli by noncoding RNAs, and establish locus-targeted
143 We propose that FRGY2a and YB1 disassemble nucleoli by sequestering B23, which is associated with p
144 ceous and membraneless organelles, including nucleoli, Cajal and PML bodies, and stress granules.
145 leoplasm and the density and permeability of nucleoli, Cajal bodies (CBs), and speckles in the Xenopu
148 ction of the endogenous FRG1 is localized in nucleoli, Cajal bodies, and actively transcribed chromat
150 number of membraneless organelles, including nucleoli, Cajal bodies, P-bodies, and stress granules, e
151 ing nucleocytoplasmic transport) and also in nucleoli, clearly visible against the less concentrated
152 oly(GR) and poly(PR), infiltrate liquid-like nucleoli, co-localize with the nucleolar protein nucleop
154 tion signals traffic through CBs en route to nucleoli, consistent with the role of CBs in small RNP a
157 that an Lsm2-Lsm7 protein complex resides in nucleoli, contributing to the biogenesis or function of
159 tumors revealed hypercelluarity, pleomorphic nucleoli, cytological atypia and necrosis, and positive
160 their neurotoxicity included aggregation in nucleoli, decreased number of processing bodies, and str
163 Ds allow time-lapse imaging of chromatin and nucleoli during cell division and Caenorhabditis elegans
164 ogy and contributes to the reorganization of nucleoli during infection.IMPORTANCE Nucleolar biology i
168 ized L5 and L11 continue to be imported into nucleoli even after nucleolar disruption and colocalize
171 ikingly, assessment of the morphology of the nucleoli exposed an abnormal nucleolar structure in Pf1-
175 oteomic profiling of purified wild-type mESC nucleoli identified a total of 613 proteins, only ~60% o
177 -PK, but not other cNHEJ factors, resides in nucleoli in an rRNA-dependent manner and is co-purified
178 distributed to the ribosomal RNA (rRNA)-rich nucleoli in cells treated with the DNA-damaging agents c
181 demonstrate that Misu translocates from the nucleoli in interphase to the spindle in mitosis as an R
183 ylated histone H3 that normally circumscribe nucleoli in oocytes and early embryos, respectively.
186 ive analysis of the molecular composition of nucleoli in skin fibroblasts and iPSC derived from them.
187 Furthermore, while FAM111A localized to nucleoli in uninfected cells in a cell cycle-dependent m
191 nt delocalization of paraspeckle proteins to nucleoli is an early event in PS-ASO toxicity, followed
192 on of heterodimer proteins P54nrb and PSF to nucleoli is an early event in the pathway that explains
193 NBS1-dependent recruitment of TOPBP1 in the nucleoli is required for inhibition of ribosomal RNA syn
195 dation/alkylation in mammalian cells; within nucleoli it interacts with nucleophosmin and rRNA throug
196 nternalization and decrease in the number of nucleoli; (iv) increase in the number of pericentromeric
201 ynthesized ribosomal proteins accumulated in nucleoli more quickly than other nucleolar components.
203 oteins in major nuclear organelles including nucleoli, nuclear speckles, Cajal bodies, as well as in
204 for anti-RNAP I/III antibodies clearly stain nucleoli, nucleolar staining is inconsistent and cannot
205 ins, DNA, RNA, and lipids were determined in nucleoli, nucleoplasmic transcription sites, nuclear spe
208 d corneal fibroblasts, ZO-1 was localized to nucleoli of both serum-starved and serum-treated cells.
210 The Raman maps show the nucleus and the nucleoli of cells as well as subcellular organization in
212 1 protein (which localizes to the nuclei and nucleoli of cells) interacts with both IRS-1 and the SV4
214 ntrast, it colocalized with nucleolin in the nucleoli of corneal fibroblasts after serum-starved cell
215 In Xenopus somatic cell nuclear cloning, the nucleoli of donor nuclei rapidly and almost completely d
218 lysis for Raman spectra measured in the same nucleoli of HeLa cells before and after fixation by eith
219 -fluorescein stains the cytosol, nuclei, and nucleoli of HeLa cells under conditions where the Ru-oct
221 ass densities of cytoplasm, nucleoplasm, and nucleoli of human cell lines, challenged by various pert
223 (ANG) protein, which entered the nuclei and nucleoli of infected cells and stimulated 45S rRNA gene
224 also observed an accumulation of Gag in the nucleoli of infected cells derived from mammary gland tu
228 romolecules and protein conformations in the nucleoli of iPSC and human embryonic stem cells (hESC) w
229 cleolar disassembly, FRGY2a localized to the nucleoli of isolated nuclei and was capable of disassemb
232 Our earlier report that BIG1 concentrated in nucleoli of serum-starved HepG2 cells prompted us to ide
233 ids and protein conformations indicates that nucleoli of skin fibroblasts contain similar subsets of
235 ccumulation of Ran-GTP, which accumulates at nucleoli of transfected or infected cells, thus perturbi
237 that RNA polymerase II (Pol II) inside human nucleoli operates near genes encoding rRNAs to drive the
238 e staining patterns partially overlap in the nucleoli, promotes ATF5 protein degradation through prot
239 interaction of IRS-1, PI3-K, and UBF1 in the nucleoli provides one of the mechanisms for the effects
240 ed in over 4500 human proteins from purified nucleoli, providing enhanced coverage of the nucleolar p
241 al and proteomics approaches to characterize nucleoli purified from cultured human and mouse cells.
242 l a strong correlation between disruption of nucleoli, reduced association of RAG1 with a nucleolar m
246 associated with heterochromatic regions and nucleoli, respectively, where yeast Sir2 functions; 2) S
249 ymerase III (Pol III)-transcribed genes with nucleoli seems to be an evolutionarily conserved propert
251 umulated multiple kinetoplasts, flagella and nucleoli, similar to the effects of RNAi-dependent knock
252 consistent with phase separation, including nucleoli, stress granules, Cajal bodies, and numerous ad
254 ei and was capable of disassembling purified nucleoli, suggesting a direct interaction between FRGY2a
256 ted TDP-43 was specifically recruited to the nucleoli, suggesting that p-T153/Y155 regulates a previo
257 rules of engagement between these p-arms and nucleoli takes on added significance as describing the t
259 asmic shuttling protein, mainly localized at nucleoli, that plays a key role in several cellular func
260 asmic shuttling protein, mainly localized at nucleoli, that plays a number of functions in ribosome b
261 l CRs toward both the nuclear border and the nucleoli, the former being enhanced in nonproliferating
263 markers for organelles or regions, including nucleoli, the nuclear envelope, nuclear speckles, centro
264 mponents of membrane-less organelles such as nucleoli, the nuclear pore complex and stress granules.
266 t mutually exclusive) hypothesis centered on nucleoli: the specialized intranuclear domains within wh
270 Co-migration of RNase H1 and R-loops from nucleoli to perinucleolar ring structures was observed u
271 ction and recruitment of heterochromatin and nucleoli to the nuclear lamina facilitates the folding o
273 localization of NPM1 and BER components from nucleoli to the nucleoplasm, and cellular experiments ta
274 While unprocessed POLGARF localizes to the nucleoli together with its interacting partner C1QBP, se
280 lular fractionation, virions accumulating in nucleoli were found to retain infectivity in secondary i
283 dering a recent finding that, in dead cells, nucleoli were targeted by C1q and two nucleolar autoanti
285 These data show that mTORC1 is located in nucleoli where it acts to regulate events involved in ri
286 found in different subcellular compartments-nucleoli, where it associates with ribosomal RNA and is
287 ate 1 (IRS-1) translocates to the nuclei and nucleoli, where it binds to the upstream binding factor
288 mponents raptor and mTOR are both present in nucleoli, where they may regulate rRNA maturation events
289 ary for the localization of c-Myc protein to nucleoli, whereas c-Myc nucleolar localization is indepe
290 primarily nuclear and largely excluded from nucleoli, whereas PP1gamma and to a lesser extent PP1bet
291 abidopsis thaliana are present within sorted nucleoli, whereas silenced rRNA genes are excluded.
292 GFP fusion protein localized specifically to nucleoli, whereas the N-terminal sequence of SelH fused
295 53 by release of ribosomal proteins from the nucleoli, which bind to MDM2 and inhibit p53 degradation
296 sulting in misdirection of telomerase RNA to nucleoli, which prevents telomerase from elongating telo
299 firmed that nucleolin localizes primarily to nucleoli with RNA polymerase I, we demonstrated that nuc