ライフサイエンスコーパス: nucleolin

1 this protein in vivo such as those linked to Nucleolin.

2 that this can be rescued by the addition of nucleolin.

3 f cellular 14-3-3zeta mRNA levels by the RBP nucleolin.

4 ining overlapping binding sites for REST and nucleolin.

5 ected from exosomal decay by the addition of nucleolin.

6 associated with cytoplasmic localization of nucleolin.

7 plasmic sites, which did not colocalize with nucleolin.

8 o other nucleolar proteins, nucleophosmin or nucleolin.

9 s likely to be involved in its regulation by nucleolin.

10 tly increased in patients with low levels of nucleolin.

11 ntrols the spatial dynamics and functions of nucleolin.

12 tion sequence RNA-binding proteins, SBP2 and nucleolin.

13 forming oligonucleotide aptamer that targets nucleolin.

14 rboxy terminus typically found in vertebrate nucleolin.

15 ed it as Modulo, the Drosophila homologue of nucleolin.

16 n with the polyfunctional RNA-binding factor nucleolin.

17 by the trans-acting effects of supplemental nucleolin.

18 d after heat shock by complex formation with nucleolin.

19 dent on direct or indirect interactions with nucleolin.

20 ates revealed association of UL84, UL44, and nucleolin.

21 with vector and a non-Fas-binding mutant of nucleolin.

22 n-resistant Fas complex selectively included nucleolin.

23 includes annexin A2, TLR4, calreticulin, and nucleolin.

24 potentiates TNT formation independent of the nucleolin-14-3-3zeta axis, despite biochemically interac

25 thiocyanate (FITC)-AS1411 to plasma membrane nucleolin 56 +/- 10% SE (P < 0.01) compared with cells i

26 GF; matrix metalloproteinases-2 and -9), and nucleolin (a nuclear protein involved with synthesis and

27 We sought to determine whether nucleolin, a bcl-2 mRNA-binding protein, has a role in t

28 In addition, nucleolin, a classic histone chaperone, was demonstrated

29 Unexpectedly, nucleolin, a major protein component of the nucleolus, w

30 We found that nucleolin, a multifunctional phosphoprotein, binds in vi

31 We found that nucleolin, a nucleolar protein involved in ribosomal mat

32 Nucleoli are rich in nucleolin, a potent transcription factor that we found t

33 of full-length HDV RNAs, it colocalized with nucleolin, a predominant nucleolar protein.

34 eiling a previously unknown interaction with Nucleolin, a protein proposed as an ideal target for can

35 AS1411 binds to nucleolin, a protein that is overexpressed in the cytopl

36 L) mRNA half-life by reducing its binding to nucleolin, a protein that normally binds a 3' AU-rich re

37 Nucleolin, a protein with histone chaperone activity, in

38 Down-regulation of nucleolin abrogates the nucleosome disruption, the recru

39 Here, we show that nucleolin abundance is controlled posttranscriptionally

40 with RNA polymerase I, we demonstrated that nucleolin allows RNA polymerase I transcription of chrom

41 cted to stabilize Hdm2, we instead find that nucleolin also reduces Hdm2 protein levels, demonstratin

42 Specifically, nucleolin, an essential nucleolar protein, preferentiall

43 nal complementation experiments suggest that nucleolin and 14-3-3zeta form a linear signaling axis th

44 segment in a nuclear territory with abundant nucleolin and active PolII molecules.

45 -2) transcripts was reduced, indicating that nucleolin and AUF1 have opposing roles in bcl-2 mRNA tur

46 model that illustrates the opposing roles of nucleolin and AUF1 in regulating bcl-2 mRNA stability.

47 nockdown of nucleolin in MCF-7 cells reduced nucleolin and bcl-2 protein levels and decreased the hal

48 Cytoplasmic localization of nucleolin and Bcl-x(L) mRNA stabilization required HGF a

49 These findings indicate that nucleolin and beta1 integrin are present on the luminal

50 min has affinity for the eucaryotic proteins nucleolin and beta1 integrin.

51 cleus and regulates CD39 by interacting with nucleolin and heterogeneous-nuclear-ribonucleoprotein-A1

52 in vitro studies, we demonstrated that both nucleolin and hnRNP K bind selectively to the G- and C-r

53 efficacy of the aptamer AS1411 in targeting nucleolin and inducing bcl-2 mRNA instability and cytoto

54 e nucleosome disruption is also dependent on nucleolin and is required for recruitment of replication

55 V4-11 cells to AS1411, showed no full-length nucleolin and lesser amounts of the truncated forms of n

56 eres with the stabilization of bcl-2 mRNA by nucleolin and may be one mechanism by which AS1411 induc

57 caused degradation of the nucleolar proteins nucleolin and nucleophosmin 1.

58 Syk binds robustly to nucleolin and phosphorylates it on tyrosine, enhancing i

59 not interact directly with either Pol II or nucleolin and that forms of deltaAg which support replic

60 he absence of pUL31, CMV fails to reorganize nucleolin and UBF and exhibits a replication defect at a

61 ther, our results indicate an association of nucleolin and UL44 in HCMV-infected cells and a role for

62 The association of nucleolin and UL44 in infected cell lysate was confirmed

63 Furthermore, the colocalization of nucleolin and UL44 in infected cell nuclei was observed

64 These changes were dependent on nucleolin and were not observed in cells pretreated with

65 , we sought to compare the proximity of Tir, nucleolin, and beta1 integrin to regions of EHEC O157:H7

66 d the translocation required importin beta1, nucleolin, and Smad2/3.

67 Here we show that nucleolin, another protein critical for rRNA processing,

68 The nucleolin antagonist N6L strongly impaired the growth of

69 Anti-nucleolin antibodies interacted with a 110-kDa form in s

70 BrdU incorporation, binding of i.v.-injected nucleolin antibodies, and MT1-MMP immunostaining in a su

71 on of the plasma membrane fraction with anti-nucleolin antibody demonstrated the presence of [(32)P]A

72 Anti-nucleolin antibody inhibited binding of fluorescein isot

73 conjugated to a broad-range tumor-targeting nucleolin aptamer inhibited tumor growth in multiple tum

74 Treatment with the chemically-synthesized nucleolin aptamer-TAP siRNA conjugate represents a broad

75 tation assays indicated that IRS1, TRS1, and nucleolin are candidates for such interactions in infect

76 We show that 14-3-3zeta and nucleolin are required for the formation of TNTs between

77 Our results identify nucleolin as a key regulator of VEGF-D expression, deepe

78 In this study, we purified and identified nucleolin as a protein that allows RNA polymerase II to

79 hyl sulfate (DMS) footprinting technique and nucleolin as a structural probe specifically recognizing

80 rum WW led to the recognition of the protein nucleolin as a target antigen.

81 hy and mass spectrometry, we have identified nucleolin as an additional protein that binds to a palin

82 x-forming oligodeoxynucleotide that binds to nucleolin as an aptamer, but its mechanism of action is

83 cl-2 3'-untranslated region that is bound by nucleolin as well as the protein binding domains importa

84 intimin, which binds host cell integrins and nucleolin, as well as a receptor (Tir) that it injects i

85 of symmetrical dimethylarginine (sDMA), is a nucleolin-associated protein whose localization and acti

86 colocalized with the host nucleolar protein nucleolin at the peripheries of both replication compart

87 ucleolin increases during infection and that nucleolin becomes distributed throughout the nucleus.

88 leolin binding in cells by both siRNAs and a nucleolin binding aptamer greatly increased LTR promoter

89 lencing activity; in contrast, disruption of nucleolin binding in cells by both siRNAs and a nucleoli

90 t HGF stabilized Bcl-x(L) mRNA by increasing nucleolin binding to the 3'-untranslated region that was

91 Alterations in p53 levels arise from nucleolin binding to the p53 antagonist Hdm2, resulting

92 Our results show that cell surface nucleolin binds Fas, inhibits ligand binding, and thus p

93 In summary, nucleolin binds G-rich sequences in the CR and UTRs of t

94 immunoprecipitation analyses indicated that nucleolin binds the KLF2 promoter only upon application

95 NA fragment binding assays demonstrated that nucleolin binds to a 40-nucleotide region at the 5' end

96 Finally, we show that nucleolin binds to the c-myc promoter in HeLa cells, whi

97 Nucleolin blockade by RNAi-mediated silencing or pharmac

98 is through enhanced binding, suggesting that nucleolin blocks the FasL-Fas interaction.

99 t both phosphorylated and non-phosphorylated nucleolin-bound DNA; however, only phosphorylated nucleo

100 During infection, pUL31 colocalizes with nucleolin but not the transcriptional activator, UBF.

101 Evidence that BIG1 and nucleolin, but not fibrillarin, can be present with p62

102 NA affinity chromatography and identified as nucleolin by mass spectrometry analysis.

103 Consequently, reducing the level of nucleolin by RNA interference attenuates the ability of

104 Knockdown of nucleolin by RNA interference resulted in specific inhib

105 cl-X(L) mRNA in HeLa cells, whereas reducing nucleolin by small interfering RNA shortens the Bcl-X(L)

106 Nucleolin can bind to the primary miRNA both directly an

107 Finally, we show that in the absence of nucleolin, cell extracts are unable to process miR-15a/1

108 noted immunostained Tir beneath and stained nucleolin closely associated with adherent bacteria in i

109 Nucleolin colocalized with Fas on the surface of B-cell

110 y demonstrated the presence of [(32)P]AS1411-nucleolin complexes.

111 ation by affecting the activities of certain nucleolin-containing complexes.

112 with true late kinetics and is localized to nucleolin-containing nuclear domains.

113 Antibodies against BIG1 or nucleolin coprecipitated both proteins from nuclei, whic

114 is issue of Blood, Allinne et al propose the nucleolin-dependent activation of the translocated CCND1

115 ctivation of c-Jun NH(2)-terminal kinase and nucleolin-dependent mRNA stabilization.

116 t a conceptually novel mechanism involving a Nucleolin-dependent Nanog-p53 bistable switch regulating

117 ing is highly sensitive to the efficiency of nucleolin-dependent ribosomal processing.

118 As bearing the G-rich motif, since silencing nucleolin did not change target mRNA stability, but decr

119 ioning of nucleolin in this pathway and that nucleolin directly interacts with DGCR8 and Drosha in th

120 In vitro binding assays showed that purified nucleolin discriminates among SECIS elements in the abse

121 Nucleolin distribution was altered, supporting that eith

122 AR including PAR polymerase-1, 2 (PARP1, 2), nucleolin, DNA ligase III, KU70, KU86, XRCC1, and histon

123 Nucleolin does not alter p53 ubiquitination by human pap

124 Moreover, immunofluorescence of BRCA1 and nucleolin double-labeling showed colocalization in both

125 Nucleolin enhanced the translation of mRNAs bearing the

126 We speculate that 3'UTR-bound nucleolin enhances mRNA stability by optimizing alphaCP

127 Additionally, nucleolin exhibited dynamic flow-specific, PI3K-dependen

128 ome selenoprotein mRNAs over others, whereas nucleolin exhibits minimal differences in binding.

129 Nucleolin exists in several isoforms, and we report that

130 investigation indicated that JNK2 regulated nucleolin expression and might in turn stabilize hif-1al

131 cleolin genetic sequence selectively reduced nucleolin expression and was sufficient to block the ind

132 ancer cells, but the mechanisms that control nucleolin expression are unknown.

133 Our collective findings indicate that nucleolin expression is positively regulated by HuR and

134 ve superhelicity, where relative hnRNP K and nucleolin expression shifts the equilibrium to the on or

135 iR-494 as a microRNA that potently inhibited nucleolin expression, enhanced NCL mRNA association with

136 due in part to the HuR-elicited increase in nucleolin expression.

137 miR-15a/16 levels are directly correlated to nucleolin expression.

138 HuR functionally competed for modulation of nucleolin expression.

139 onal activity determined by its target gene, Nucleolin, expression.

140 addition, we demonstrate that upon binding, nucleolin facilitates the formation and increases the st

141 We confirmed the presence of nucleolin-Fas complexes in B-cell lymphoma cells and pri

142 s a good correlation between the affinity of nucleolin for a SECIS and its effect on selenoprotein ex

143 Antibodies against nucleolin from mice or from transplant patients inhibite

144 ling of RNAs immunoprecipitated with BIG1 or nucleolin from nuclei revealed bands of approximately 21

145 This cellular signalling cascade recruits nucleolin from the nuclei of cells to the plasma membran

146 subunit minimizes the inhibitory effects of nucleolin GAR or TM expression on chromosomal DNA replic

147 eaf venation, corresponds to the Arabidopsis nucleolin gene.

148 imal or yeast cells, plants contain a second nucleolin gene.

149 re, we report that Arabidopsis NUC1 and NUC2 nucleolin genes are both required for plant growth and s

150 tion of small interfering RNAs targeting the nucleolin genetic sequence selectively reduced nucleolin

151 Thus, nucleolin has a number of properties in common with the

152 illarin, nucleoporin p62, and La in BIG1 and nucleolin immunoprecipitates.

153 r envelope confirms the presence of BIG1 and nucleolin in dynamic molecular complexes that change in

154 These data support a general role for nucleolin in gene regulation and identify it as a novel

155 Stable siRNA knockdown of nucleolin in MCF-7 cells reduced nucleolin and bcl-2 pro

156 l knockdown of plasma membrane and cytosolic nucleolin in MCF-7 cells resulted in a 3-fold decrease i

157 and to a 4-fold higher level of cytoplasmic nucleolin in MCF-7 cells.

158 When the function of nucleolin in MV-4-11 cells was impaired by treatment wit

159 may have roles similar to those of the yeast nucleolin in nuclear signal recognition, ribosomal proce

160 dly, we also found localization of UL84 with nucleolin in nucleoli and showed that the presence of nu

161 evidence for the oncogenic role of JNK2 and nucleolin in regulating the cancer microenvironments by

162 Multiparameter analysis of BRCA1 and nucleolin in relation to cell cycle position (DNA conten

163 d to previous work showing the importance of nucleolin in replication compartment architecture and vi

164 for AS1411 action as well as a new role for nucleolin in stimulating macropinocytosis, a process wit

165 In contrast, it colocalized with nucleolin in the nucleoli of corneal fibroblasts after s

166 iral DNA, and the cellular nucleolar protein nucleolin in the subnuclear replication compartments in

167 g with bcl-2 mRNA for binding to cytoplasmic nucleolin in these breast cancer cell lines.

168 on is critical for the proper functioning of nucleolin in this pathway and that nucleolin directly in

169 d UL44 in HCMV-infected cells and a role for nucleolin in viral DNA synthesis.

170 riven switch in the biological activities of nucleolin in vivo.

171 scence assays demonstrated that the level of nucleolin increases during infection and that nucleolin

172 Nucleolin inhibition directly affected endothelial cell

173 In conclusion, nucleolin inhibition is a new anti-pancreatic cancer the

174 Among the vascular activators, nucleolin inhibition significantly decreased angiopoieti

175 uces Hdm2 protein levels, demonstrating that nucleolin inhibits Hdm2 using multiple mechanisms.

176 cleolar proteins, including nucleostemin and nucleolin into the nucleoplasm.

177 Nucleolin is a c-Myc-induced gene product with defined r

178 esults provide evidence that plasma membrane nucleolin is a functional receptor for AS1411 in MV4-11

179 Nucleolin is a major nucleolar protein implicated in man

180 Nucleolin is a marker of nucleoli, which are membrane-le

181 We conclude that nucleolin is a novel binding partner and substrate for P

182 performed to determine whether cell surface nucleolin is a receptor for AS1411 in the acute myeloid

183 analysis revealed that the cellular protein nucleolin is able to specifically recognize G-quadruplex

184 PRMT5 and that distribution of sDMA-modified nucleolin is altered by AS1411.

185 Nucleolin is an entry coreceptor for RSV(2) and also med

186 noprecipitation experiments established that nucleolin is associated with chromatin containing rRNA g

187 in nucleoli and showed that the presence of nucleolin is involved in localization of UL84 to the nuc

188 Nucleolin is one of the proteins that binds to bcl-2 mRN

189 Nucleolin is overexpressed in cancers and its inhibition

190 e other hand, down-regulation of 14-3-3s and nucleolin is potentially involved in the process of kera

191 The glycine/arginine-rich C terminus of nucleolin is required for binding, and the four RNA reco

192 Furthermore, nucleolin is required for the induction smooth muscle al

193 nce and mutational analysis demonstrate that nucleolin is required for the nuclear transport of scuPA

194 Based on siRNA experiments, nucleolin is required for the optimal expression of cert

195 refore propose that an important function of nucleolin is to permit RNA polymerase I to transcribe nu

196 inary molecular interaction data show that a nucleolin isoform binds to a 5' stem-loop of the coding

197 In addition, our data indicate that nucleolin itself is a substrate for PRMT5 and that distr

198 erfering RNA (siRNA) experiments showed that nucleolin knockdown enhances SSAT translation.

199 Nucleolin knockdown sensitized BJAB cells to Fas ligand

200 Nucleolin levels are high in cancer cells, but the mecha

201 Increases in nucleolin levels in unstressed cells led to higher expre

202 We propose that nucleolin, like ARF, responds to hyperproliferative sign

203 As immunofluorescence confirmed that nucleolin localizes primarily to nucleoli with RNA polym

204 In summary, nucleolin may induce c-myc G4 formation in vivo.

205 el to effects from hydroxyurea, knockdown of nucleolin mobilized capsids to the nucleoplasm and incre

206 with small interfering RNA (siRNA) targeting nucleolin mRNA indicated that nucleolin was required for

207 oted nucleolin translation without affecting nucleolin mRNA levels.

208 The RBP HuR was found to interact with the nucleolin (NCL) 3'UTR and specifically promoted nucleoli

209 Nucleolin (NCL) is a nucleocytoplasmic protein involved

210 The multifunctional protein nucleolin (NCL) is overexpressed on the surface of activ

211 In contrast, nucleolin (NCL) suppresses the translation of p53 mRNA a

212 Nucleolin (NCL) was identified to be EBNA1 associated.

213 RPL4 and Nucleolin (NCL) were a scaffold for an EBNA1-induced ori

214 Here we find that nucleolin (NCL), a major nucleolar protein, posttranscri

215 We report that Nucleolin (Ncl), a nucleolar protein that regulates rRNA

216 ene ranks, functional studies of our top-hit Nucleolin (Ncl), abundant in stem and cancer cells, reve

217 ribonucleoproteins (hnRNPs) R, Q and L, and nucleolin (NCL), appeared to interact specifically with

218 alizes with the multifunctional host protein nucleolin (NCL).

219 ilar to the yeast (Saccharomyces cerevisiae) nucleolin NUCLEAR SIGNAL RECOGNITION 1 (NSR1) multifunct

220 at synthetic ligands binding to cell surface nucleolin/nucleophosmin and known as HB 19 for the lead

221 nd dissociation from the molecular chaperone Nucleolin occur in p16-silenced cells, abrogating its pr

222 and lesser amounts of the truncated forms of nucleolin on the cell surface.

223 The presence of nucleolin on the KLF2 promoter in macrophages was verifi

224 nucleolin target mRNAs and the influence of nucleolin on their expression had not been studied at a

225 ing RNA (siRNA)-mediated silencing of either nucleolin or hnRNP K resulted in the down-regulation of

226 Furthermore, we provide evidence that nucleolin overexpression reduces the activity of a c-myc

227 Interestingly, nucleolin physically interacted with polyadenylate [poly

228 V infection with the nucleolar protein, with nucleolin playing a role in maintaining the architecture

229 previous mechanistic model but confirm that nucleolin plays a role in mediating AS1411 effects.

230 of matrix metalloproteinases, endostatin and nucleolin poorly correlated with detraining-induced capi

231 These data indicate that nucleolin possesses a specific and regulated activity to

232 her nucleolar proteins B23/nucleophosmin and nucleolin, previously shown to interact with AAV2 capsid

233 and that AS1411 causes relocalization of the nucleolin-PRMT5 complex from the nucleus to the cytoplas

234 The RNA-binding protein (RBP) nucleolin promotes the expression of several proliferati

235 y AS1411 results from both interference with nucleolin protection of bcl-2 mRNA and recruitment of th

236 d on these data, we propose a model in which nucleolin protects the Bcl-X(L) mRNA from nuclease degra

237 Timing of nucleolin protein expression differed between muscle gro

238 Here we find that changes in nucleolin protein levels in unstressed cells cause paral

239 y, we reported that the Arabidopsis thaliana nucleolin protein NUC1, an abundant and evolutionarily c

240 tive or repressed state of the NORs and that nucleolin proteins play a key role in the developmental

241 linked immunosorbent assay, with recombinant nucleolin (r-nucleolin), the frequency of antibodies to

242 The observed colocalization of BRCA1 and nucleolin raises new possibilities for the nucleoplasm-n

243 us-targeting agent that selectively disrupts nucleolin/rDNA G-quadruplex complexes in the nucleolus,

244 Nucleolin recognized with high affinity and specificity

245 A nucleolin-recognizing aptamer was coupled to peptide sca

246 ANKRD1, in association with factors such as nucleolin, represses MMP13 transcription.

247 eous nuclear ribonucleoprotein (hnRNP) K and nucleolin, respectively, both in vitro and in vivo and t

248 nterfering RNA (siRNA)-mediated knockdown of nucleolin resulted in a dramatic elimination of UL84FLAG

249 energy transfer studies demonstrate that the nucleolin-RPA interaction after stress occurs both in th

250 Antibodies against nucleolin seem to inhibit and produce apoptosis of proli

251 iRNA-treated cells, our results suggest that nucleolin selectively enhances the expression of a subse

252 usly, we proposed a model where cell surface nucleolin serves as the receptor for AS1411, leading to

253 d were not observed in cells pretreated with nucleolin-specific small interfering RNA.

254 Further study showed that nucleolin specifically recognized the AU-rich elements (

255 Furthermore, overexpression of nucleolin stabilizes the Bcl-X(L) mRNA in HeLa cells, wh

256 olin-bound DNA; however, only phosphorylated nucleolin successfully competed with either full-length

257 used to screen for endogenous repressors of nucleolin synthesis.

258 However, the subset of nucleolin target mRNAs and the influence of nucleolin on

259 , and used them to find a signature motif on nucleolin target mRNAs.

260 Here, we globally identified nucleolin target transcripts, many of which encoded cell

261 -11 cells was impaired by treatment with the nucleolin-targeting aptamer AS1411, association of AUF1

262 Nucleolin that normally resides in the innermost fibrill

263 sorbent assay, with recombinant nucleolin (r-nucleolin), the frequency of antibodies to nucleolin wer

264 ey regulate the degree of phosphorylation of nucleolin through a novel kinase-independent phosphotran

265 uPA to the nucleocytoplasmic shuttle protein nucleolin through a region containing the kringle domain

266 Nucleolin, through its RNA-binding domains (RBDs), binds

267 The response of VEGF and nucleolin to acute exercise was blunted with training, a

268 Czeta activation prevents the trafficking of nucleolin to RSV particles on airway organoid cultures,

269 AS1411 also inhibited the binding of nucleolin to the instability element AU-rich element 1 o

270 ere was a redistribution of both deltaAg and nucleolin to the nucleoplasm.

271 itation analysis further revealed binding of nucleolin to the promoter region of the VEGF gene in viv

272 blocked the shear stress-induced binding of nucleolin to the promoter, demonstrating its PI3K-depend

273 ncing HuR, suggesting that the repression of nucleolin translation may occur in PBs.

274 leolin (NCL) 3'UTR and specifically promoted nucleolin translation without affecting nucleolin mRNA l

275 al nucleolar structure with dysregulation of nucleolin turnover.

276 Our data demonstrate that BIG1, nucleolin, U3, the U3-binding protein fibrillarin, and t

277 o binding of selenoprotein mRNAs by SBP2 and nucleolin via immunoprecipitation of the proteins and qu

278 Nucleolin was identified as one of the binding proteins

279 rbitol, and the intranuclear distribution of nucleolin was monitored by confocal microscopy.

280 Nucleolin was not required for initial FL-AS1411 uptake

281 Herein, we showed that nucleolin was overexpressed in human specimens of pancre

282 Recombinant nucleolin was produced and sera were assayed for antibod

283 ption, whereas the expression of 14-3-3s and nucleolin was reduced.

284 RNA) targeting nucleolin mRNA indicated that nucleolin was required for efficient virus production, v

285 The nucleolin was transferred into the nucleoplasm, but it d

286 RNAs, deltaAg moved to the nucleoplasm, but nucleolin was unchanged.

287 in 4 and the glycine/arginine-rich domain of nucleolin were essential for its association with Fas.

288 r-nucleolin), the frequency of antibodies to nucleolin were found to be 2.0% in normal subjects, 9.1%

289 Ribosomal protein L26 (RPL26) and nucleolin were found to bind to the 5' untranslated regi

290 elial growth factor-A (VEGF), endostatin and nucleolin were increased at 2-4 h (P < 0.05), whereas ma

291 full-length (106 kDa) and truncated forms of nucleolin were present on the cell surface.

292 Mice transfected with nucleolin were protected from the lethal effects of agon

293 The first two RNA binding domains of nucleolin were sufficient for high affinity binding to A

294 Rp72 (endoplasmic reticulum protein 72), and nucleolin, were identified, and their interactions with

295 we report that the RNA-binding protein (RBP) nucleolin, which interacts with the known TNT-inducing p

296 We also demonstrated that nucleolin, which is known to bind to G-quadruplex struct

297 recipitation analyses associated ANKRD1 with nucleolin, which represses AP-1 activation of MMP13.

298 d that fluid flow induced the interaction of nucleolin with the p85 regulatory subunit of PI3K.

299 The RBP nucleolin, with four RNA-recognition motifs, has been im

300 l precipitated by antibodies against BIG1 or nucleolin yielded identical nucleotide sequences that al