ライフサイエンスコーパス: nucleosome assembly

1 hat Scm3 plays an active role in centromeric nucleosome assembly.

2 , and the 26S proteasome generally, in plant nucleosome assembly.

3 tin and the proteins required for new CENP-A nucleosome assembly.

4 eosomes, while the reverse reaction promotes nucleosome assembly.

5 h the regulation of gene expression and H3.3 nucleosome assembly.

6 Rtt109, the H3 lysine 56 KAT, to promote RC nucleosome assembly.

7 to CAF-1, a histone chaperone involved in RC nucleosome assembly.

8 n of the N-terminal residues of H3 and H4 in nucleosome assembly.

9 ces of genome-scale, replication-independent nucleosome assembly.

10 leosome positioning sequences favored during nucleosome assembly.

11 stent with their role in replication-related nucleosome assembly.

12 passage, in this case by promoting efficient nucleosome assembly.

13 t, the substrate for replication-independent nucleosome assembly.

14 CAT interruptions in (CAG)n tracts decreased nucleosome assembly.

15 required for efficient DNA synthesis-coupled nucleosome assembly.

16 storage, sperm chromatin decondensation, and nucleosome assembly.

17 H3 or H4 is required for replication-coupled nucleosome assembly.

18 ot equalCG in terms of facilitating archaeal nucleosome assembly.

19 interphase centromeres to promote new CENP-A nucleosome assembly.

20 hromatin assembly factor-1 (CAF-1)-dependent nucleosome assembly.

21 in egg extract under conditions that titrate nucleosome assembly.

22 nized these lysines in yeast and assayed for nucleosome assembly.

23 ent human H4 is therefore completed prior to nucleosome assembly.

24 one acetylation conferred by yCAF-I-mediated nucleosome assembly.

25 leosomal loop of DNA, suggesting a means for nucleosome assembly.

26 e most favored DNA sequences yet defined for nucleosome assembly.

27 e re-establishes both cellular viability and nucleosome assembly.

28 AgNCs did not affect nuclear membrane or nucleosome assembly.

29 hosphorylation for histone H3-H4 binding and nucleosome assembly.

30 as they are transported into the nucleus for nucleosome assembly.

31 responsible for histone H3/H4 deposition and nucleosome assembly.

32 s only moderate effects on H3-H4 binding and nucleosome assembly.

33 way, and enters the nucleus where it impedes nucleosome assembly.

34 AF-1*H3-H4 binding mode and the mechanism of nucleosome assembly.

35 nes to regulate the thermodynamic process of nucleosome assembly.

36 anded DNA, has a role in replication-coupled nucleosome assembly.

37 for FACT to deposit histones onto DNA during nucleosome assembly.

38 H3-H4)2 tetramers during replication-coupled nucleosome assembly.

39 nvolved in the nuclear import of H2A-H2B and nucleosome assembly.

40 in interphase, resulting in defective CENP-A nucleosome assembly.

41 tion itself does not directly interfere with nucleosome assembly.

42 formation of the HIRA-H3.3 complex and H3.3 nucleosome assembly.

43 rlying Nap1-mediated H2A-H2B chaperoning and nucleosome assembly.

44 sis for Nap1-mediated H2A-H2B deposition and nucleosome assembly.

45 ith the DNA replication forks and subsequent nucleosome assembly.

46 a cells depends on the function of Rtt106 in nucleosome assembly.

47 Modification of histones H3 and H4 prevented nucleosome assembly.

48 PCNA unloading is delayed in the absence of nucleosome assembly.

49 intain opportunity for CAF-1 recruitment and nucleosome assembly.

50 ependent on new histone supply and efficient nucleosome assembly.

51 are then transferred to other chaperones for nucleosome assembly.

52 re and gene expression are both regulated by nucleosome assembly.

53 en histone acetylation and ubiquitylation in nucleosome assembly.

54 osed to function in replication-coupled (RC) nucleosome assembly, a process critical for the inherita

55 he absence of DNA replication and stimulated nucleosome assembly activity by recombinant yeast CAF-I

56 defective for PCNA binding displayed reduced nucleosome assembly activity in vitro but were stimulate

57 oth in vitro and in vivo, and it displayed a nucleosome assembly activity in vitro.

58 This unanticipated nucleosome assembly activity of AM-PARP-1, coupled with

59 tion is to recruit HJURP and that the CENP-A nucleosome assembly activity of HJURP is responsible for

60 geting domain of Cse4 is sufficient for Scm3 nucleosome assembly activity.

61 protein SET after Lys(176) and disrupted its nucleosome assembly activity.

62 s histone-binding domains and inhibiting its nucleosome assembly activity.

63 Chromatin inheritance entails de novo nucleosome assembly after DNA replication by chromatin a

64 ex, a histone chaperone that is required for nucleosome assembly after DNA replication, in the wing i

65 ncluding K14 also delayed replication-depend nucleosome assembly and advanced replicative life span.

66 14,000) host genes probed, comprising mainly nucleosome assembly and binding, central nervous system

67 In Wwox(-/-) mice, genes related to nucleosome assembly and cell growth genes were down-regu

68 etrameric state can be used as substrates in nucleosome assembly and chaperone-mediated lysine acetyl

69 As nucleosome assembly and chromatin remodeling are importa

70 1 in H2A/H2B deposition and exchange, during nucleosome assembly and chromatin remodeling in vivo.

71 functional distinction between ATP-dependent nucleosome assembly and chromatin remodeling, and sugges

72 roteins that are central to the processes of nucleosome assembly and disassembly and thus the fluidit

73 nstration of the dynamic equilibrium between nucleosome assembly and disassembly at the single chroma

74 on during Pol II elongation, suggesting that nucleosome assembly and disassembly occur in a stepwise

75 hought to be the first and the last steps in nucleosome assembly and disassembly, respectively.

76 by facilitating histone exchange as well as nucleosome assembly and disassembly.

77 s implicated in histone shuttling as well as nucleosome assembly and disassembly.

78 exasomes and tetrasomes are intermediates in nucleosome assembly and disassembly.

79 e in escorting histones to and from sites of nucleosome assembly and disassembly.

80 The pentameric domain assists nucleosome assembly and forms a discrete complex with pr

81 sition in the nucleosome with regard to both nucleosome assembly and gene regulation.

82 itates Chromatin Transcription) functions in nucleosome assembly and H2A-H2B deposition during transc

83 rk for understanding how Vps75 mediates both nucleosome assembly and histone acetylation by Rtt109.

84 rminal region is revealed to be critical for nucleosome assembly and histone exchange.

85 Chromatin structure is dictated by nucleosome assembly and internucleosomal interactions.

86 DNA-binding) proteins regulate ATP-dependent nucleosome assembly and mobilization through their conse

87 vitro but, surprisingly, is dispensable for nucleosome assembly and only makes a modest contribution

88 of CGG repeat expansion and methylation for nucleosome assembly and positioning on the Fragile X Men

89 the consequences of CTG repeat expansion for nucleosome assembly and positioning.

90 uitylated by the Rtt101(Mms1) ligase impairs nucleosome assembly and promotes Asf1-H3 interactions.

91 ed important roles of Dhx15 in chromatin and nucleosome assembly and regulation of the Mdm2-p53 pathw

92 complex and regulated process that includes nucleosome assembly and remodeling, deposition of histon

93 egulate HIRA-H3.3 complex formation and H3.3 nucleosome assembly and reveal the mechanism by which OG

94 dea that the effects of the spt mutations on nucleosome assembly and/or stability activate repressors

95 odifications that accompany DNA replication, nucleosome assembly, and H2A/H2B exchange were examined

96 ing mobile and nonmobile chaperones, de novo nucleosome assembly, and read-write mechanisms that modi

97 nucleosomes, the machinery that accomplishes nucleosome assembly, and the functional organization of

98 ults also indicate that the slowest steps in nucleosome assembly are DNA termini wrapping and tetrame

99 ponding lysine acetyltransferase (KAT) in RC nucleosome assembly are not known.

100 Further, by using nucleosome assembly assays, we demonstrate that these tw

101 shed light on the mechanism of Scm3-mediated nucleosome assembly at the centromere.

102 This approach resulted in nucleosome assembly beginning immediately downstream of

103 To understand differences in centromeric nucleosome assembly between K. lactis and S. cerevisiae,

104 ASF1b to facilitate DNA replication-coupled nucleosome assembly, but how TLKs selectively target the

105 e that H3.3-specific residues involved in RI nucleosome assembly-but not major histone modification s

106 However, nucleosome assembly by hyperacetylated histones on inter

107 This is an example of selective nucleosome assembly by Xenopus nuclear extracts on a sho

108 ing transcription regulation (TIF1alpha) and nucleosome assembly (CAF1).

109 NAPs have been reported to have a role in nucleosome assembly, cell cycle regulation, cell prolife

110 s, both interruptions permit a propensity of nucleosome assembly closer to that of random (geneticall

111 expression is Yki-dependent, suggesting that nucleosome assembly competes with Yki for pathway target

112 Thus, the HIR complex is a novel nucleosome assembly complex which functions with SWI/SNF

113 on onto DNA in vitro and constitutes a novel nucleosome assembly complex.

114 es were found to direct a similar pattern of nucleosome assembly, consistent with the view that nucle

115 ere with Nap1 oligomerization exhibit severe nucleosome assembly defects showing that oligomerization

116 During this phase, nascent CENP-A nucleosome assembly depends on the maternal Cenpa genoty

117 How the very first step in nucleosome assembly, deposition of histone H3-H4 as tetr

118 simple, intrinsically stochastic process of nucleosome assembly, disassembly, and position-specific

119 to a simple model involving a noncooperative nucleosome assembly/disassembly equilibrium, suggesting

120 Here, we show that the nucleosome assembly/disassembly process is not strictly

121 amic packaging of the genome by carrying out nucleosome assembly/disassembly, histone exchange, and n

122 ific enrichment in functions associated with nucleosome assembly, DNA repair, metal ion binding, and

123 ocalization patch in addition to loss of the nucleosome assembly domain.

124 these CGG repeats abolishes the preferential nucleosome assembly due to methylation.

125 H3, has been implicated in the regulation of nucleosome assembly during DNA replication and repair, a

126 ative system could communicate the degree of nucleosome assembly during DNA replication and the need

127 uggesting that FACT and Ubp10 may coordinate nucleosome assembly during DNA replication and transcrip

128 Surprisingly, PIP2 is essential for nucleosome assembly during DNA replication in vitro and

129 uring the cell cycle to provide histones for nucleosome assembly during DNA replication.

130 enhances these turnover events and promotes nucleosome assembly during S phase.

131 lated at lysine 56 (H3K56ac) and facilitates nucleosome assembly during several molecular processes.

132 d biochemically tractable when compared with nucleosome assembly during simian virus 40 (SV40) DNA re

133 sstalk between MMR and replication-dependent nucleosome assembly during the correction of DNA replica

134 mbedded centromeres by blocking conventional nucleosome assembly early in S phase, thereby allowing t

135 t the GAA GAA TTC triplex further lowers the nucleosome assembly efficiency (82% decrease compared to

136 lly similar functions of H2B ubiquitylation (nucleosome assembly) elicit different functional outcome

137 ES cells lacking the nucleosome assembly factor HirA exhibit elevated levels

138 ASF1 is a nucleosome assembly factor which is a member of the H3/H

139 replication initiation factor, securin gene, nucleosome assembly factor, and a subunit of the cohesin

140 show that Scm3 functions as a Cse4-specific nucleosome assembly factor, and that the resulting octam

141 the activity of Scm3(HJURP), the centromeric nucleosome assembly factor.

142 chaperone Scm3 functions as a Cse4-specific nucleosome assembly factor.

143 teract with multiple DNA replication-coupled nucleosome assembly factors, including Rtt106, CAF-1, an

144 Nucleosome assembly following DNA replication and gene t

145 Nucleosome assembly following DNA replication controls e

146 endent manner but is also capable of de novo nucleosome assembly from histone octamer because of its

147 ly-distributed nucleosomes are formed by the nucleosome assembly function of Chd1, and then regularly

148 the nucleosome core particles nor displayed nucleosome assembly function, suggesting it may not be d

149 one variant Cse4 to centromeres, its role in nucleosome assembly has not been tested.

150 s, plasmid superhelicity in whole cells, and nucleosome assembly in cell extracts.

151 ric sites in metaphase for subsequent CENP-A nucleosome assembly in interphase.

152 nt protein regulates DNA replication-coupled nucleosome assembly in part through regulating histone-h

153 play an important but redundant function in nucleosome assembly in the budding yeast, Saccharomyces

154 ed understanding of the factors that mediate nucleosome assembly in the nascent male pronucleus, the

155 ng to the results, CpG methylation expedites nucleosome assembly in the presence of abundant DNA and

156 bited upon deletion of Hira due to a lack of nucleosome assembly in the sperm genome.

157 Nucleosome assembly in the wake of DNA replication is a

158 reased expression of histones or a defect in nucleosome assembly in the yeast Saccharomyces cerevisia

159 similar to NAP-1, NLP, and Nph, facilitates nucleosome assembly in vitro and is therefore a histone

160 ional and rotational positioning of archaeal nucleosome assembly in vitro by a sequence from the 7S R

161 al region of yNAP1, although dispensable for nucleosome assembly in vitro, contributes to binding via

162 ToRC facilitates ATP-dependent nucleosome assembly in vitro.

163 ent with these findings, Spt6p is capable of nucleosome assembly in vitro.

164 We also analyzed nucleosome assembly in vivo and in vitro by examining pl

165 the histone amino termini are important for nucleosome assembly in vivo and in vitro.

166 Nucleosome assembly in vivo requires assembly factors, s

167 The histone H4 mutants are competent for nucleosome assembly in vivo, and the residues that are a

168 During nucleosome assembly in vivo, newly synthesized histone H

169 Therefore, K5/K12 cannot be required for nucleosome assembly in yeast.

170 e results demonstrate that Gcn5 regulates RC nucleosome assembly, in part, by promoting H3 associatio

171 ctural components of H3 and H4 necessary for nucleosome assembly into metazoan chromosomes in vivo.

172 Nucleosome assembly is a highly regulated process that r

173 Replication-coupled nucleosome assembly is a major step in packaging the new

174 The first step in replication-coupled nucleosome assembly is CAF-1-dependent histone (H3-H4)2

175 one chaperones have been identified, but how nucleosome assembly is coupled to DNA replication remain

176 stem for the analysis of replication-coupled nucleosome assembly is described.

177 DNA replication-coupled nucleosome assembly is essential to maintain genome inte

178 Our results reveal that replication-coupled nucleosome assembly is necessary to generate a bilateral

179 In this "two-step system," nucleosome assembly is performed in a separate reaction

180 Because the nucleosome assembly is performed separately from the DNA

181 transcription initiation, on which archaeal nucleosome assembly is positioned downstream from the si

182 e every cell cycle during G1, but how CENP-A nucleosome assembly is spatially and temporally restrict

183 CENP-A nucleosome assembly is uncoupled from replication and oc

184 and why high AT DNA content, which disfavors nucleosome assembly, is widely conserved at centromeres.

185 They show that defects in nucleosome assembly lead to DNA double-strand breaks and

186 employed to suppress kinetic bottlenecks in nucleosome assembly, lead to cooperative behavior that c

187 derstanding of the mechanisms of centromeric nucleosome assembly, maintenance, and reorganization rem

188 ypothesized that the information controlling nucleosome assembly may coincide with the information th

189 ose different chaperone-assisted binding and nucleosome assembly mechanisms for the canonical and CEN

190 which H3K56Ac regulates replication-coupled nucleosome assembly mediated by CAF-1 and Rtt106.

191 We investigated nucleosome assembly mediated by histone chaperone Nap1 a

192 clear transport, nucleotide excision repair, nucleosome assembly, membrane trafficking, and cytoskele

193 New CENP-A nucleosome assembly occurs at the centromere every cell

194 e examined the effects of these drugs on the nucleosome assembly of DNA molecules that display differ

195 chanism whereby H4S47ph distinctly regulates nucleosome assembly of H3.1 and H3.3.

196 ts indicate that HAT1 differentially impacts nucleosome assembly of H3.1-H4 and H3.3-H4.

197 nucleosome assembly of H3.3-H4 and inhibits nucleosome assembly of H3.1-H4 by increasing the binding

198 7ph), catalyzed by the PAK2 kinase, promotes nucleosome assembly of H3.3-H4 and inhibits nucleosome a

199 How HIRA-mediated nucleosome assembly of H3.3-H4 is regulated remains not

200 racts with UBN1, modifies HIRA, and promotes nucleosome assembly of H3.3.

201 SAHF formation depends on HIRA-mediated nucleosome assembly of histone H3.3, which is regulated

202 ble) sequences, suggesting an association of nucleosome assembly of trinucleotide repeats and genetic

203 ective in H3-H4 binding exhibited attenuated nucleosome assembly on nascent chromatin.

204 as a model system to determine the effect of nucleosome assembly on nucleotide excision repair (NER)

205 to increased and decreased propensities for nucleosome assembly on the (CAG)n and (CGG)n repeats, re

206 omes and by an increase in the efficiency of nucleosome assembly on the injected plasmid.

207 We have used magnetic tweezers to study nucleosome assembly on topologically constrained DNA mol

208 verify our hypothesis that the lack of full nucleosome assembly on topologically constrained tethers

209 The FRA16B DNA fragments strongly exclude nucleosome assembly only in the presence of distamycin,

210 , it was shown that H2Bub1 was important for nucleosome assembly onto nascent DNA at active replicati

211 sites are not necessary for CAF-1-dependent nucleosome assembly onto replicated DNA.

212 e spatial configuration of the COMPASS-H2Bub-nucleosome assembly, our studies establish the structura

213 roliferating cell nuclear antigen (PCNA) for nucleosome assembly, participates in the establishment o

214 hat CAC is a key intermediate of the de novo nucleosome assembly pathway and that the p48 subunit par

215 er, these results reveal that the CAF-1-PCNA nucleosome assembly pathway plays an important role in t

216 zed histones in this DNA replication-coupled nucleosome assembly pathway remain enigmatic.

217 and ssDNA gaps interfere with the ASF1-CAF-1 nucleosome assembly pathway, and drive fork degradation

218 ors influence histone nuclear import and the nucleosome assembly pathway, leading to changes in chrom

219 e histone octamer, with implications for the nucleosome assembly pathway.

220 ote the entry of histones H3 and H4 into the nucleosome assembly pathway.

221 p among modifications, histone variants, and nucleosome assembly pathways is unclear.

222 ne modifications are tied to the alternative nucleosome assembly pathways that use primarily H3 at re

223 th histone H4, into nucleosomes via distinct nucleosome assembly pathways.

224 oximal to the H2A docking domain that drives nucleosome assembly, positioning it for transfer to the

225 nascent DNA, Okazaki fragment processing and nucleosome assembly potentially affect one another.

226 B dimers was generally poor, suggesting that nucleosome assembly precedes and inhibits HSF binding.

227 ost probably in the form of twist) stall the nucleosome assembly process.

228 H4K5,12ac differentially regulate these two nucleosome assembly processes.

229 Concomitant nucleosome assembly protects the discontinuous mismatch-

230 The nucleosome assembly protein (NAP) family represents a ke

231 This gene is homologous to yeast nucleosome assembly protein (NAP1) and to a human homolo

232 cribe the cloning and analysis of Drosophila nucleosome assembly protein 1 (dNAP-1), a core histone-b

233 emodeling factor (ACF), purified recombinant nucleosome assembly protein 1 (dNAP1), purified native c

234 re we show that the acidic histone chaperone nucleosome assembly protein 1 (NAP-1) from yeast reversi

235 On separation of nuclear proteins, nucleosome assembly protein 1 (Nap-1) has an overlapping

236 Nucleosome assembly protein 1 (NAP-1) is an integral com

237 coactivator p300, we obtained cDNAs encoding nucleosome assembly protein 1 (NAP-1), a 60-kDa histone

238 Homologues of nucleosome assembly protein 1 (NAP1) are found throughou

239 found that the cytoplasmic histone chaperone nucleosome assembly protein 1 (Nap1) associates with the

240 The histone chaperone nucleosome assembly protein 1 (NAP1) is implicated in hi

241 d adding an excess of the histone chaperone, nucleosome assembly protein 1 (NAP1) to the H3/H4 prior

242 We find that the histone chaperone, nucleosome assembly protein 1 (NAP1), cooperates with CB

243 Histone chaperones, like nucleosome assembly protein 1 (Nap1), play a critical ro

244 of chromatin (RSC) and the histone chaperone nucleosome assembly protein 1 (NAP1).

245 mechanism of action of the histone chaperone nucleosome assembly protein 1 (Nap1).

246 actors, including histone chaperones such as nucleosome assembly protein 1 (Nap1).

247 Here we demonstrate that nucleosome assembly protein 1 (Nap1p), a protein previou

248 The self-association properties of the yeast nucleosome assembly protein 1 (yNAP1) have been investig

249 The yeast nucleosome assembly protein 1 (yNAP1) participates in ma

250 The yeast nucleosome assembly protein 1 (yNap1) plays a role in ch

251 similar overall architecture with the yeast nucleosome assembly protein 1 and human SET/TAF-1beta/IN

252 3/H4 during their deposition on DNA by NAP1 (nucleosome assembly protein 1).

253 helicase-interacting protein 1), along with nucleosome assembly protein 1, as novel ubiquitin-intera

254 Several unbiased screens identified nucleosome assembly protein 1-like 1 (NAP1L1) as an inte

255 This factor, called nucleosome assembly protein 1-like 1 (NAP1L1), is a nucl

256 Here, we show that nucleosome assembly protein 1-like protein 1 (NAP1L1) as

257 mber of cellular proteins, in particular the nucleosome assembly protein 1-like protein 1 (NAP1L1), b

258 ion vehicle used for this analysis was NAP1, nucleosome assembly protein 1.

259 ue of NAP1, and we designate it hNAP2 (human nucleosome assembly protein 2).

260 The truncated TSPYL1 protein that lacks the nucleosome assembly protein domain was retained in the G

261 a peptide domain with strong homology to the nucleosome assembly protein family.

262 The nucleosome assembly protein Nap1 is used extensively in

263 GzmA cleaved the nucleosome assembly protein SET after Lys(176) and disru

264 ch contains three granzyme A substrates, the nucleosome assembly protein SET, the DNA bending protein

265 ociated complex (SET complex) containing the nucleosome assembly protein SET, the tumor suppressor pp

266 to downregulate the expression of NAP1L2, a nucleosome assembly protein we show to be important for

267 es, two histone modification proteins, and a nucleosome assembly protein were detected, clearly indic

268 xNAP1 (Xenopus nucleosome assembly protein) belongs to the family of nu

269 ompared the abilities of dNLP and Drosophila nucleosome assembly protein-1 (dNAP-1) to promote the de

270 release that was enhanced by the presence of nucleosome assembly protein-1 (NAP1).

271 mbly and remodeling factor (ACF), Drosophila nucleosome assembly protein-1, plasmid DNA, and ATP.

272 interacts with nap1, which encodes the NAP-1 nucleosome assembly protein.

273 TSPYL2 is an X-linked gene encoding a nucleosome assembly protein.

274 Nucleosome assembly proteins (Nap proteins) represent a

275 e assembly protein) belongs to the family of nucleosome assembly proteins (NAPs) and shares 92% ident

276 e 6 and encodes a protein with homology with nucleosome assembly proteins (NAPs); it has tissue-speci

277 ny factors, including the four HIR genes and nucleosome assembly proteins Asf1p and chromatin assembl

278 identified an mRNA, belonging to a family of nucleosome assembly proteins, whose expression is upregu

279 coupling of fork speed and PCNA unloading to nucleosome assembly provides a simple mechanism to adjus

280 IPs are capable of preferentially inhibiting nucleosome assembly, rather than DNA synthesis, suggesti

281 overed components of the replication-coupled nucleosome assembly (RCNA) pathway.

282 w Nap1 and Kap114 cooperate in transport and nucleosome assembly remains unclear.

283 We present evidence for a paradigm in which nucleosome assembly requires the elimination of competin

284 CENP-A nucleosome assembly requires the Mis18 complex and the C

285 CENP-A nucleosome assembly requires the three-protein Mis18 com

286 ate DNA-synthesis-dependent and -independent nucleosome assembly, respectively.

287 acts occur during concomitant nick-dependent nucleosome assembly shaped by the replication histone ch

288 eosomes replicated in the absence of de novo nucleosome assembly showed that histone modifications do

289 lates one of two Arabidopsis homologs of the nucleosome assembly/silencing protein Asf1 and histone H

290 , our understanding of how it influences the nucleosome assembly, structure, and dynamics remains obs

291 block is 4.9 +/- 0.6-fold less efficient in nucleosome assembly than a similar length pUC19 fragment

292 -fold and 2.1 +/- 0.3-fold less efficient in nucleosome assembly than the respective unmethylated for

293 o aid in understanding the thermodynamics of nucleosome assembly, the equilibrium stabilities of the

294 Indeed, oocytes lack any measurable CENP-A nucleosome assembly through the entire fertile lifespan

295 at as few as six CTG repeats will facilitate nucleosome assembly to a similar extent as the 50 or mor

296 iation suggests that HMG2 may facilitate the nucleosome assembly, transcriptional activation, and DNA

297 Nucleosome assembly was assayed by three methods.

298 Here, we investigate the mechanism of nucleosome assembly with a purified chromatin assembly s

299 replication fork, through which RPA couples nucleosome assembly with ongoing DNA replication.

300 l cycle surveillance mechanism that monitors nucleosome assembly without involving the DNA repair pat