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1 that contain caspase-recruitment (CARD) and nucleotide-binding oligomerization domains.
2 e mediated by Toll-like receptors (TLRs) and nucleotide binding oligomerization domain 1 (Nod1) prote
5 so caused decreased stimulation of the human nucleotide-binding oligomerization domain 1 (Nod1) proin
6 le possesses potent stimulatory activity for nucleotide-binding oligomerization domain 1 (Nod1), an i
10 uridarum induces IFN-beta via stimulation of nucleotide-binding oligomerization domain 1 pathway, and
12 g to the development of colitis in mice with nucleotide binding oligomerization domain 2 (NOD2) defic
13 Retinoic acid-induced gene-I (RIG-I) and nucleotide binding oligomerization domain 2 (NOD2) serve
15 y few studies have addressed the function of nucleotide-binding oligomerization domain 2 (NOD-2) in t
17 itude of cytokine induction after individual nucleotide-binding oligomerization domain 2 (Nod2) and T
19 have confirmed prior findings related to the nucleotide-binding oligomerization domain 2 (NOD2) gene
20 immunity, the intracellular pathogen sensor nucleotide-binding oligomerization domain 2 (NOD2) has b
25 mutations and corresponding abnormalities of nucleotide-binding oligomerization domain 2 (NOD2) prote
26 actors regulating Crohn's disease-associated nucleotide-binding oligomerization domain 2 (Nod2) respo
27 models of colitis and the involvement of the nucleotide-binding oligomerization domain 2 (NOD2) signa
28 at correlate with the expression of CYLD and nucleotide-binding oligomerization domain 2 (NOD2), 2 st
29 by which mutations in CARD15, which encodes nucleotide-binding oligomerization domain 2 (NOD2), caus
30 dipeptide (MDP), the microbial activator of nucleotide-binding oligomerization domain 2 (Nod2), indu
32 ICOS and the ICOS ligand on MDDCs amplified nucleotide-binding oligomerization domain 2 (NOD2)-initi
33 Although Toll-like receptor 4 (TLR4)- and nucleotide-binding oligomerization domain 2 (NOD2)-media
37 ffects were mediated through binding to TLR2/nucleotide-binding oligomerization domain 2 and TLR3/MDA
38 ase domain with RIPK4's did not complement a nucleotide-binding oligomerization domain 2 signaling or
39 lasmatic pattern recognition receptor, NOD2 (nucleotide-binding oligomerization domain 2), belongs to
40 ted with impaired signaling through TLR2 and nucleotide-binding oligomerization domain 2, two recepto
41 enotype showed increased JAK2 expression and nucleotide-binding oligomerization domain 2-induced JAK2
42 AA carrier macrophages switched to increased nucleotide-binding oligomerization domain 2-induced proi
43 by the intracellular bacterial sensor NOD2 (nucleotide-binding, oligomerization domain 2) as an anti
44 tern recognition receptors (PRRs), including nucleotide-binding oligomerization domain-2 (NOD2) (vari
47 tion and function of Toll-like receptors and nucleotide-binding oligomerization domain-2, and mainten
48 mechanisms balancing toll-like receptor and nucleotide-binding-oligomerization domain activation in
49 , and mutation studies suggest that both the nucleotide binding oligomerization domain and the leucin
50 spase-1-activating proteins, which contain a nucleotide-binding oligomerization domain and leucine-ri
51 disrupted the ability of TRIM22 to regulate nucleotide binding oligomerization domain containing 2 (
53 ion of the IL-23/IL-17A axis is regulated by nucleotide-binding oligomerization domain containing (No
54 We hypothesized that polymorphisms in the nucleotide-binding oligomerization domain containing 2 (
55 ), IL10 -3575T>A (rs1800890, rs1800896), and nucleotide-binding oligomerization domain containing 2 (
56 activates innate immune cells by stimulating nucleotide-binding oligomerization domain containing 2 (
58 We found that upon stimulation of the PRR nucleotide-binding oligomerization domain containing 2 (
59 Recognition of symbiotic bacteria via the nucleotide-binding oligomerization domain containing 2 (
60 during streptozotocin (STZ)-induced T1D, the nucleotide-binding oligomerization domain containing 2 (
61 biochemical mechanism by which mutations in nucleotide-binding oligomerization domain containing 2 (
62 innate stimuli from house dust mite extract, nucleotide-binding oligomerization domain containing 2 l
64 he discovery that polymorphisms in the NOD2 (nucleotide-binding oligomerization domain containing 2)
65 gnition receptors, including TLR4, TLR7, and nucleotide-binding oligomerization domain containing 2,
67 y disease linked to specific variants in the nucleotide-binding oligomerization domain containing pro
68 of T-bet, intercellular adhesion molecule-1, nucleotide-binding oligomerization domain containing-2,
69 e of this study was to elucidate the role of nucleotide binding oligomerization domain-containing pro
70 MARCO was required for maximal TLR2- and nucleotide-binding oligomerization domain-containing (No
73 6L-1), immunity-related GTPase-M (IRGM), and nucleotide-binding oligomerization domain-containing 2 (
74 f the Crohn's disease susceptibility protein nucleotide-binding oligomerization domain-containing 2 (
75 , such as nitric oxide, toll-like receptors, nucleotide-binding oligomerization domain-containing pro
77 recognition receptors (Toll-like receptor 2, Nucleotide-binding oligomerization domain-containing pro
78 muropeptides that more effectively activates nucleotide-binding oligomerization domain-containing pro
79 y, we found that activation of monocytes via nucleotide-binding oligomerization domain-containing pro
81 on molecules, including Toll-like receptors, nucleotide-binding oligomerization domain-containing pro
83 or Toll-like receptors (TLRs) 7-9 as well as nucleotide-binding oligomerization domain-containing pro
86 mal regulation of the innate immune receptor nucleotide-binding oligomerization domain-containing pro
87 nd synergistically enhanced by activation of nucleotide-binding oligomerization domain-containing pro
88 ppressor of cytokine signaling-3, rs4969170; nucleotide-binding oligomerization domain-containing pro
89 by C-C chemokine receptor (CCR) 2, CCR5, and nucleotide-binding oligomerization domain-containing pro
90 nic chlamydial species are known to activate nucleotide-binding oligomerization domain-containing pro
91 k components of bacterial sensing, including nucleotide-binding oligomerization domain-containing pro
92 the cytoplasmic pattern recognition receptor nucleotide-binding oligomerization domain-containing pro
95 In this study, we investigated the role of nucleotide-binding oligomerization domain-containing pro
96 tes a specific pattern recognition molecule, nucleotide-binding oligomerization domain-containing pro
98 mune sensors, including Toll-like receptors, nucleotide-binding oligomerization domain-containing rec
100 the intracellular bacteria-sensing protein, nucleotide-binding oligomerization domaining-containing
101 k between two pattern recognition receptors: nucleotide-binding oligomerization-domain-containing pro
102 sis and biological evaluation of a series of nucleotide-binding oligomerization-domain-containing pro
103 is, and biological evaluation of a series of nucleotide-binding oligomerization-domain-containing pro
104 gnaling via the pattern recognition receptor nucleotide-binding, oligomerization domain-containing pr
105 ow-derived macrophages from various TLRs and nucleotide-binding oligomerization domain-deficient mice
106 in 2, a component of the recently discovered nucleotide-binding oligomerization domain-dependent intr
107 the main cellular mechanisms responsible of nucleotide-binding oligomerization domain family, pyrin
109 amilies: the Toll-like receptors (TLRs), the nucleotide-binding oligomerization domain leucine rich r
110 e macrophages require Naip5, a member of the nucleotide-binding oligomerization domain leucine-rich r
113 p65/RelA deacetylation and inactivation, and nucleotide-binding oligomerization domain, leucine rich
114 ty to enhance inflammation by activating the nucleotide-binding oligomerization domain, leucine rich
115 ncentrations of 25 nmol/L or greater induced nucleotide-binding oligomerization domain, leucine-rich
116 ceptor-interacting protein 1, IFNbeta-1, and nucleotide-binding oligomerization domain, leucine-rich
117 volvement of "inflammasomes", especially the nucleotide-binding oligomerization domain, leucine-rich
118 d that inhibiting the ATPase activity of the nucleotide-binding oligomerization domain, leucine-rich
120 , including IL-1 receptor (IL-1R) family and nucleotide-binding oligomerization domain, leucine-rich
121 TRIF-related adapter molecule, IRF-3, HIF-1, nucleotide-binding oligomerization domain, leucine-rich
122 attern-recognition receptor in the family of nucleotide-binding oligomerization domain-leucine-rich r
123 ticular inflammation by targeting the NLRP3 (nucleotide-binding oligomerization domain-, leucine-rich
124 subsequently leads to the activation of NOD (nucleotide-binding oligomerization domain)-like receptor
125 We analyzed the expression profile of NOD (nucleotide-binding oligomerization domain)-like receptor
127 of genes encoded for components of the TLR, nucleotide binding oligomerization domain-like receptor,
129 containing anti-dsDNA Abs by activating the nucleotide-binding oligomerization domain-like receptor
130 y, we show that cyclic stretch activates the nucleotide-binding oligomerization domain-like receptor
132 retinoic acid-inducible gene 1 (RIG-1), and nucleotide-binding oligomerization domain-like receptor
133 dies in mouse macrophages, activation of the nucleotide-binding oligomerization domain-like receptor
134 ammasome activation through interaction with nucleotide-binding oligomerization domain-like receptor
135 ith PGN inhibited cross-presentation through nucleotide-binding oligomerization domain-like receptor
136 t key roles for Toll-like receptor (TLR) and nucleotide-binding oligomerization domain-like receptor
138 of thioredoxin-interacting protein with the nucleotide-binding oligomerization domain-like receptor
139 or innate cytokines and signaling by TLR and nucleotide-binding oligomerization domain-like receptor
140 FN, apoptosis-associated speck-like protein, nucleotide-binding oligomerization domain-like receptor
141 mmatory response involving activation of the nucleotide-binding oligomerization domain-like receptor
144 nfection, coordinating the activation of the nucleotide-binding oligomerization domain-like receptor
148 he inflammasome activation, mainly of NLRP3 (nucleotide-binding oligomerization domain-like receptor
151 mediated by Toll-like receptor 4 (TLR4) and nucleotide-binding oligomerization domain-like receptor
153 ween the retinoic acid-inducible gene-I-like/nucleotide-binding oligomerization domain-like receptor
154 We show that while chronic alcohol induces nucleotide-binding oligomerization domain-like receptor
155 including, cytokine and chemokine signaling, nucleotide-binding oligomerization domain-like receptor
157 c acid-inducible gene 1-like receptor (RLR), nucleotide-binding oligomerization domain-like receptor
158 eta precursor requires processing by the the nucleotide-binding oligomerization domain-like receptor
160 s of the inflammasome, often proteins of the nucleotide-binding oligomerization domain-like receptor
162 how that the absent in melanoma 2 (AIM2) and nucleotide-binding oligomerization domain-like receptor
164 e define that the host mitochondrial protein nucleotide-binding oligomerization domain-like receptor
165 n of bone marrow-derived macrophages via the nucleotide-binding oligomerization domain-like receptor
167 a secretion is mediated by activation of the nucleotide-binding oligomerization domain-like receptor
168 ansfected bone marrow-derived macrophages is nucleotide-binding oligomerization domain-like receptor
170 hisms in genes encoding Toll-like receptors, nucleotide-binding oligomerization domain-like receptor-
171 atory effects of the innate immune molecule, nucleotide-binding oligomerization domain-like receptors
172 tors, such as Toll-like receptors (TLRs) and nucleotide-binding oligomerization domain-like receptors
177 ven different human TLRs or one of two human nucleotide-binding oligomerization domain-like receptors
178 Caspase-1 activation triggered by multiple nucleotide-binding oligomerization domain-like receptors
180 acterized PRRs include, in addition to TLRs, nucleotide-binding oligomerization domain-like receptors
181 une pattern-recognition receptors, including nucleotide-binding oligomerization domain-like receptors
182 e intracellular immunity receptors, known as nucleotide-binding oligomerization domain-like receptors
183 lysaccharide of Gram-negative microbes-while nucleotide-binding oligomerization domain-like receptors
184 eceptors (TLRs), cytosolic receptors such as nucleotide-binding oligomerization domain-like receptors
185 infection with a virulent microbe, TLRs and nucleotide-binding oligomerization domain-like receptors
187 n B in M1 cells, revealing activation of the nucleotide-binding, oligomerization domain-like receptor
188 anotoxicity and sterile inflammation via the nucleotide-binding, oligomerization domain-like receptor
190 factor)-receptor signaling and NLRP3 (NOD- [nucleotide-binding oligomerization domain], LRR- [leucin
191 Pharmacological inhibition of NLRP3 (NOD [nucleotide-binding oligomerization domain]-' LRR [leucin
195 tivation of the P2X7 purinergic receptor and nucleotide binding oligomerization domain (NOD)-like rec
196 Recent studies also identified the role of nucleotide binding oligomerization domain (NOD)-like rec
198 ffect of the T2S system was not dependent on nucleotide binding oligomerization domain (NOD)-like rec
201 ptides) activate innate immune cells through nucleotide-binding oligomerization domain (NOD) 1 and/or
206 bacterial sensors, it was proposed that the nucleotide-binding oligomerization domain (NOD) proteins
207 of PRR such as Toll-like receptors (TLR) and nucleotide-binding oligomerization domain (NOD) proteins
210 philus influenzae (Hi) required both TLR and nucleotide-binding oligomerization domain (NOD) signalin
211 s, a growing family of proteins containing a nucleotide-binding oligomerization domain (NOD), are inv
212 , termed the inflammasome, by members of the nucleotide-binding oligomerization domain (Nod), leucine
214 ation of immune response pathways, including nucleotide-binding oligomerization domain (NOD)-, Toll-,
216 the areas of toll-like receptors (TLRs) and nucleotide-binding oligomerization domain (NOD)-containi
218 we highlight recent advances on the roles of nucleotide-binding oligomerization domain (NOD)-like rec
219 ar pattern recognition receptors such as the nucleotide-binding oligomerization domain (NOD)-like rec
220 protein complexes assembled by intracellular nucleotide-binding oligomerization domain (NOD)-like rec
224 mmasome scaffolds comprised of intracellular nucleotide-binding oligomerization domain (NOD)-like rec
228 yrin domain containing 1 (NLRP1), NLRP3, and nucleotide-binding oligomerization domain (NOD)-like rec
229 oligomeric/fibrillar aSyn could activate the nucleotide-binding oligomerization domain (NOD)-like rec
230 eostasis and integrity are maintained by the nucleotide-binding oligomerization domain (NOD)-like rec
233 also promote inflammation by activating the nucleotide-binding oligomerization domain (NOD)-like rec
234 ptors (PRRs), such as Toll-like receptors or nucleotide-binding oligomerization domain (NOD)-like rec
235 which are structurally similar to mammalian nucleotide-binding oligomerization domain (NOD)-like rec
240 of primary peritoneal mesothelial cells via nucleotide-binding oligomerization domain (Nod)1, a memb
241 -regulation of toll-like receptor (TLR)2 and nucleotide-binding oligomerization domain (NOD)2 pathway
242 S: Polymorphisms that reduce the function of nucleotide-binding oligomerization domain (NOD)2, a bact
244 bial sensors, recent evidence indicates that nucleotide-binding oligomerization domains (NODs) can al
245 ssociated with missense mutations within the nucleotide-binding oligomerization domain of cryopyrin.
246 Intersections between toll-like receptor and nucleotide-binding-oligomerization domain pathways may e
249 the Toll-like receptors 1, 2, and 4 and the nucleotide-binding oligomerization domain protein 1 indu
251 in immune cells, although they activate the nucleotide-binding oligomerization domain proteins in tr
252 he lysosomal digestion products activate the nucleotide-binding oligomerization domain proteins.
253 Pathways activated by functional cytosolic nucleotide-binding-oligomerization domain proteins appea
255 ll-like receptor 1 (TLR1), TLR2, TLR4, TLR6, nucleotide-binding oligomerization domain receptor 1 (NO
256 ition is partially mediated by intracellular nucleotide-binding oligomerization domain receptors (NLR
257 lastic lesions in humanized fat pads of NOD (nucleotide-binding oligomerization domain)/SCID (severe