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1 (ventromedial prefrontal cortex (vmPFC) and nucleus accumbens).
2 of KOR regulation of dopamine release in the nucleus accumbens.
3 sembled from activity across the VTA and the nucleus accumbens.
4 modulation of cocaine potency at DATs in the nucleus accumbens.
5 le of glutamatergic hippocampal outputs onto nucleus accumbens.
6 panied by enhanced dopamine signaling in the nucleus accumbens.
7 of reward processing within the caudate and nucleus accumbens.
8 ced DARPP-32 phosphorylation at Thr75 in the nucleus accumbens.
9 by stimulation of oxytocin terminals in the nucleus accumbens.
10 D(1)-expressing medium spiny neurons in the nucleus accumbens.
11 ons projecting to lateral or medial shell of nucleus accumbens.
12 facilitating D(1)-mediated excitation in the nucleus accumbens.
13 and interact with distinct subregions of the nucleus accumbens.
14 or, mid- and posterior), caudate nucleus and nucleus accumbens.
15 ritical mediator of cocaine responses in the nucleus accumbens.
16 al area (VTA), with no apparent input to the nucleus accumbens.
17 ng the anterior limb of the internal capsule/nucleus accumbens.
18 ion in RGS12-null mice are restricted to the nucleus accumbens.
19 eptive opioid peptide (NOP) receptors in the nucleus accumbens.
20 m 2.42 in the globus pallidus to 8.48 in the nucleus accumbens.
21 nal measurements of dopamine dynamics in the nucleus accumbens.
23 D(1) receptors on astrocytes located in the nucleus accumbens, a key structure of the brain's reward
24 entral to this view is the engagement of the nucleus accumbens-a brain region that processes reward e
25 biting D1 medium spiny neurons (MSNs) in the nucleus accumbens-a population that has been linked to r
26 rs (D2R) in the dorsal striatum (DS) and the nucleus accumbens (Acb) jointly but differentially contr
28 t fMRI experiment, we show that learning and nucleus accumbens activation in a simple unidimensional
29 owed a positive correlation with caudate and nucleus accumbens activity during placebo, which was abs
31 f evidence for co-use differences related to nucleus accumbens activity during reward processing.
32 risk for developing chronic pain and altered nucleus accumbens activity is a signature of the state o
33 etic variation related to the volumes of the nucleus accumbens, amygdala, brainstem, caudate nucleus,
36 as negatively correlated with gaze duration (nucleus accumbens and anterior insular cortex), while tw
37 d functional connectivity locally within the nucleus accumbens and basal forebrain, and reversed the
39 ggest that the connectivity patterns for the nucleus accumbens and cortico-striatal motor circuits (p
41 drug-evoked transcriptional changes in both nucleus accumbens and dorsal striatum, dramatically incr
43 eable binding potential, particularly in the nucleus accumbens and globus pallidus, where the change
44 oscopy ((1)H-MRS) at ultra-high-field in the nucleus accumbens and inquired whether levels of glutama
45 vivo dopamine and glutamate microdialysis in nucleus accumbens and medial prefrontal cortex, and ex v
47 pocampus) and reward systems (orbital gyrus, nucleus accumbens and putamen) in driving pre-training d
48 te functional connectivity between bilateral nucleus accumbens and rostral anterior cingulate cortex
49 , connectivity changes were observed between nucleus accumbens and rostral anterior cingulate cortex
51 yporeactivity of striatal (caudate, putamen, nucleus accumbens) and cortical (insula, anterior cingul
52 adulthood on the function of the mesolimbic (nucleus accumbens) and nigrostriatal (dorsal striatum) d
54 ires activation of oxytocin receptors in the nucleus accumbens, and is recapitulated by stimulation o
55 several brain regions (ventral hippocampus, nucleus accumbens, and medial prefrontal cortex) of susc
56 NA-sequencing in the ventral tegmental area, nucleus accumbens, and prefrontal cortex of male and fem
58 changes, attenuated dopamine release in the nucleus accumbens, and reduced cocaine-seeking behavior.
60 apid upregulation of Gadd45b mRNA in the rat nucleus accumbens, and that knockout or site-specific CR
61 =51), globus pallidus internus (GPi) (n=47), nucleus accumbens/anterior limb of the internal capsule
63 eural pathway tracing analyses implicate the nucleus accumbens as a putative downstream target of vHP
64 plasticity and suggest this mechanism in the nucleus accumbens as a target for ethanol modulation of
65 ions from the anterior insular cortex to the nucleus accumbens as modulating highly compulsive-like f
66 n left rostral medial frontal gyrus and left nucleus accumbens as well as right frontal pole and left
67 ons on cocaine potency at distal DATs in the nucleus accumbens as well as the behavioral economics of
68 e gyrus, hippocampus, prefrontal cortex, and nucleus accumbens) as well as chromatin accessibility in
69 5 main reward-aversion brain centers (i.e., nucleus accumbens, bed nucleus of the stria terminalis,
70 netic activation of the basolateral amygdala-nucleus accumbens (BLA-NAc) glutamatergic circuit reduce
71 electively elevated dopamine overflow in the nucleus accumbens, but not prefrontal cortex, without in
72 ally on neuromodulatory signaling within the nucleus accumbens, but the neuronal dynamics underlying
73 itatory synapses, which are generated in the nucleus accumbens by cocaine self-administration, and su
76 ntly higher in SAD patients in the amygdala, nucleus accumbens, caudate, putamen, and posterior ventr
77 cute back pain patients showed altered local nucleus accumbens connectivity between putative shell an
80 rature has highlighted the importance of the nucleus accumbens core (NAcC) in behavioral tasks depend
81 Here, we examined a possible role for the nucleus accumbens core (NAcc) in the acquisition and exp
82 action to perform.SIGNIFICANCE STATEMENT The nucleus accumbens core (NAcC) is essential to process in
83 ts, we investigated the DNA methylome of the nucleus accumbens core (NAcc) of rhesus macaques after c
88 s is regulated by synaptic plasticity in the nucleus accumbens core and involves distinct plasticity
89 nfusions of D2R and D1R antagonists into the nucleus accumbens core and shell (NAcC; NAcS), the anter
90 for differences in dopamine signaling in the nucleus accumbens core at baseline, in response to a sin
92 of cocaine to inhibit dopamine uptake in the nucleus accumbens core using fast scan cyclic voltammetr
93 ease in mouse dorsolateral striatum, but not nucleus accumbens core, is governed by GAT-1 and GAT-3.
94 ingulate, prelimbic, and infralimbic cortex; nucleus accumbens core, medial shell, and lateral shell;
99 ter, rats were tested for their locomotor or nucleus accumbens dopamine (NAcc DA) response to ampheta
101 re body temperature and selectively enhanced nucleus accumbens dopamine release, consistent with acti
103 load and tyrosine hydroxylase levels in the nucleus accumbens, dorsal putamen and caudate using immu
104 ion in the bilateral ventral caudate and the nucleus accumbens during reward receipt relative to loss
106 ometry revealed that dopamine release in the nucleus accumbens evoked by reward-predictive cues is ac
107 nucleus; GPi, globus pallidus internus; NAc, nucleus accumbens) evoked a sufficiently distinctive blo
109 explore changes in lipid composition of the nucleus accumbens from mice subjected to two lipid diets
110 dopamine D3 receptors protein levels in the nucleus accumbens, frontal cortex and putamen were deter
112 aptations, suggesting a complete recovery of nucleus accumbens glutamatergic synaptic plasticity when
113 rojections from the prefrontal cortex to the nucleus accumbens has been argued to underlie motivation
115 alterations in medial prefrontal cortex and nucleus accumbens in human MDD and the 3 mouse chronic s
117 umental task and (2) dopamine release in the nucleus accumbens in response to electrical stimulation
118 iated with hyporeactivity exclusively in the nucleus accumbens in response to the anticipation of a r
120 These results may be relevant to roles of nucleus accumbens mechanisms in pathological motivations
121 nto D1 medium spiny neurons (D1-MSNs) in the nucleus accumbens medial shell (NAcmSh), and with latera
122 dulate behavior, with a specific emphasis on nucleus accumbens medial shell and stress responsivity.
123 ferent reward-related regions, including the nucleus accumbens, medial prefrontal cortex, and orbitof
124 matter volumes, most prominent in thalamus, nucleus accumbens, medial temporal, medial prefrontal/fr
125 synaptic potentiation (t-SP) induced in the nucleus accumbens mediates cued cocaine seeking in rat m
127 ect was seen specifically on the inputs from nucleus accumbens medium spiny neurons expressing either
128 afferents from the ventral tegmental area to nucleus accumbens (mesolimbic circuit) and frontal corte
129 ergic signaling in the reward circuit is the nucleus accumbens, more specifically, the dopamine D1 re
130 ransporter GLT-1 and glutamate efflux in the nucleus accumbens (NA) core during the reinstatement of
133 of changes in the proteomic landscape in the nucleus accumbens (NAc) and medial prefrontal cortex (mP
134 or through effects on dopamine output in the nucleus accumbens (NAc) and on neurotransmission in the
135 metry, to record haemodynamic signals in the nucleus accumbens (NAc) and orbitofrontal cortex (OFC),
136 nscriptional and morphological events in the nucleus accumbens (NAc) and other brain reward regions c
137 eptor beta (IGF-1Rbeta) were assessed in the nucleus accumbens (NAc) and ventral tegmental area (VTA)
138 from the ventral tegmental area (VTA) to the nucleus accumbens (NAc) are critical in regulating cue-m
139 xpressing medium spiny neurons (MSNs) of the nucleus accumbens (NAc) are fundamental to neuropsychiat
140 oking in human postmortem brain, focusing on nucleus accumbens (NAc) as a key brain region in develop
141 te AMPA antagonist (DNQX) in medial shell of nucleus accumbens (NAc) can cause either intense appetit
142 rowth response 3) is oppositely regulated in nucleus accumbens (NAc) cell subtypes 24 hours following
144 pression was increased in D1+ neurons in the nucleus accumbens (NAc) core and dorsolateral (DLS) stri
146 eports indicate enhancing activity of either nucleus accumbens (NAc) core MSN subtype augments reward
147 The ventromedial striatum, including the nucleus accumbens (NAc) core, is typically associated wi
149 STATEMENT Glutamatergic transmission in the nucleus accumbens (NAc) critically contributes to goal-d
151 Complex circuit interactions within the nucleus accumbens (NAc) facilitate goal-directed behavio
152 ulnerable individuals remains ambiguous, the nucleus accumbens (NAc) has been shown to play a central
154 IGNIFICANCE STATEMENT Given the roles of the nucleus accumbens (NAc) in integrating cortical and allo
156 y assessed the role of stress systems in the nucleus accumbens (NAc) in promoting sex differences in
159 ogical conditions.SIGNIFICANCE STATEMENT The nucleus accumbens (NAc) is a key part of the striatal li
162 ithin the reward circuitry, within which the nucleus accumbens (NAc) is anatomically positioned as an
163 nvestigated whether GSK3beta activity in the nucleus accumbens (NAc) is associated with depression-li
164 jection from ventral tegmental area (VTA) to nucleus accumbens (NAc) is critical for motivation to wo
169 xpression in the prefrontal cortex (PFC) and nucleus accumbens (NAc) of mice exposed to multimodal ch
171 inals in the ventral tegmental area (VTA) or nucleus accumbens (NAc) of the mesolimbic DA system.
172 e discrete projections from the vHipp to the nucleus accumbens (NAc) or prefrontal cortex (mPFC).
174 ngs indicate the insular cortex (IC) and the nucleus accumbens (NAc) play important roles in social b
175 hippocampus (vHPC) neurons projecting to the nucleus accumbens (NAc) regulates mood-related behaviora
176 ectivity (FC) of reward neurocircuitry using nucleus accumbens (NAc) seed regions of interest, and th
179 ines observed in medium spiny neurons of the nucleus accumbens (NAc) shell of alcohol-dependent rats
181 corded activity in DA terminals in different nucleus accumbens (NAc) subnuclei during an aversive and
182 aving ultimately depends on strengthening of nucleus accumbens (NAc) synapses through an accumulation
183 ection from dorsal CA1 (dCA1) hippocampus to nucleus accumbens (NAc) that enables the behavioral mani
184 s firing of CINs in both dorsal striatum and nucleus accumbens (NAc) through activation of CRF type 1
185 ests that medium spiny neurons (MSNs) in the nucleus accumbens (NAc) undergo structural plasticity; h
188 s dopamine receptor D1 (DRD1) agonist in the nucleus accumbens (NAc), a brain area involved in mediat
190 mics in medium spiny neurons (MSNs) from the nucleus accumbens (NAc), a hub of the brain's motivation
191 xamined the expression of the lncRNA Gas5 in nucleus accumbens (NAc), a key brain reward region, of a
192 t in freely behaving mice, astrocytes in the nucleus accumbens (NAc), a key reward center in the brai
193 ed in the mammalian forebrain, including the nucleus accumbens (NAc), a major neural substrate of mot
194 ission at medium spiny neurons (MSNs) in the nucleus accumbens (NAc), a region critical for reward pr
195 s reward behaviors through its action in the nucleus accumbens (NAc), but the impact of NPY on the hu
197 medial prefrontal cortex (mPFC), but not to nucleus accumbens (NAc), contributed to the antidepressi
200 ute or chronic cocaine exposure in the mouse nucleus accumbens (NAc)-a key reward region of brain.
201 CA) neurons form functional connections with nucleus accumbens (NAc)-projecting neurons of the poster
215 nforcement of non-drug rewards by increasing nucleus accumbens (NAcc) reactivity to anticipatory cues
216 er problems on adolescent depression through nucleus accumbens (NAcc) volume alteration, but not thro
217 ility in functional connectivity between the nucleus accumbens (NAcc), a key structure of the reward
218 e amygdala, anterior cingulate cortex (ACC), nucleus accumbens (NAcc), and orbitofrontal cortex (OFC)
219 and avoidance responses [bilateral amygdala, nucleus accumbens (NAcc), and ventromedial prefrontal co
220 ith volumes of the hippocampus, thalamus and nucleus accumbens (NAcc)-three subcortical regions selec
222 ral regions (i.e., increased activity in the nucleus accumbens [NAcc] and medial prefrontal cortex [M
223 s of reward-related brain regions (e.g., the nucleus accumbens [NAcc]) and unhealthy eating behaviors
224 logical restructuring of dendritic spines of nucleus accumbens neurons is thought to be one of the ce
225 ncement of total spine number in a subset of nucleus accumbens neurons that prevents stress-related e
226 ow this catalytic activity communicates with nucleus accumbens neurons to induce t-SP and cocaine see
227 such as the ventral tegmental area (VTA) or nucleus accumbens neurons, but less is known about cocai
228 erotonin efflux in the prefrontal cortex and nucleus accumbens of conscious rats were assessed using
232 ally label activated neural ensembles in the nucleus accumbens of the mouse brain during brief stimul
233 d in depression-medial prefrontal cortex and nucleus accumbens-of humans with MDD and of 3 chronic st
234 ined the effect of ZIP administration in the nucleus accumbens on reinstatement (RI) of cocaine seeki
235 examined the effect of ZIP infused into the nucleus accumbens on the reinstatement (RI) of cocaine s
237 The latest research demonstrates that in the nucleus accumbens, opioid-induced excitatory synaptic pl
238 ow this family regulates activity within the nucleus accumbens or behavioral responses to drugs of ab
239 ior limb of the internal capsule (ALIC), the nucleus accumbens or the subthalamic nucleus (STN).
241 involved in the pair-bonding process in the nucleus accumbens, our work illustrates the vast extent
243 ntal cortices, and between orbitofrontal and nucleus accumbens, predict individual differences in sen
244 f Fos-immunoreactive (Fos-ir) neurons in the nucleus accumbens predicted the frequency of the feeding
247 , we find that PVT neurons projecting to the nucleus accumbens (PVT-NAc) develop inhibitory responses
248 als in regions associated with reward (i.e., nucleus accumbens, r = 0.24), memory (i.e., hippocampus,
249 neural activation in reward-related regions (nucleus accumbens, r = 0.29; caudate nucleus, r = 0.27)
250 he anterior limb of the internal capsule and nucleus accumbens region (ALIC-NAcc) on OCD symptoms, ex
253 ng and altered glutamate connectivity in the nucleus accumbens represent the neuroanatomical basis fo
255 Analysis of the power spectral density of nucleus accumbens resting-state activity in the subacute
256 as positively associated with HOMA-IR in the nucleus accumbens, right and left insula, and right cing
257 Ablation of OFC neurons projecting to the nucleus accumbens selectively disrupted performance foll
258 e that the RMTg-ventral tegmental area (VTA)-nucleus accumbens shell (Acb) circuit plays a role in th
259 l prefrontal cortex (mPFC) projecting to the nucleus accumbens shell (AcbSh) in female Sprague Dawley
260 cal, sensory, and limbic information, to the nucleus accumbens shell (an area known to be important f
261 rojection from the infralimbic cortex to the nucleus accumbens shell (IL-NAc) is thought to inhibit c
262 ontrol over subcortical regions, such as the nucleus accumbens shell (NAcS) and basolateral amygdala,
263 ry in male Long-Evans rats to test if phasic nucleus accumbens shell (NACs) dopamine dynamics are ass
266 Compromised signaling between the mPFC and nucleus accumbens shell (NAcSh) is thought to underlie t
267 e found that cocaine-induced hypoactivity of nucleus accumbens shell (NAcSh) medium spiny neurons (MS
268 RNAi-mediated knockdown of G9a expression in nucleus accumbens shell (NAcSh) of male rats reduces bot
269 ntral tegmental area (VTA) projection to the nucleus accumbens shell (NAcSh) regulates NAcSh-mediated
270 glutamatergic projections from the IL to the nucleus accumbens shell (NAcSh) suppresses the aversive
272 asing extracellular DA concentrations in the nucleus accumbens shell (NAS) efficaciously and more pot
273 infralimbic cortex and its projection to the nucleus accumbens shell in suppressing learned negative
274 hat optical activation of the infralimbic to nucleus accumbens shell pathway attenuates learned avers
275 ts indicate an important role for the PVT to nucleus accumbens shell projections in the augmentation
277 mRNA reductions in the cingulate cortex and nucleus accumbens shell, regardless of MIA timing; (2) S
278 ral (Caudato-Putamen, DLS) and ventromedial (Nucleus Accumbens Shell, VS) striatal subregions was exa
282 ated within DS synapses, but enhanced in the nucleus accumbens, suggesting a dichotomous role of BDNF
284 ation of a discrete number of neurons in the nucleus accumbens that are causally linked to reward-rel
285 oved after dopamine receptor blockade in the nucleus accumbens; the D1R antagonist, SCH23390, in the
287 late pathways between the OFC, amygdala, and nucleus accumbens to reveal their separable contribution
289 reoptic area, hypothalamus, rostral pallium, nucleus accumbens, ventral pallidum, and bed nucleus of
290 Our results provide evidence that lower nucleus accumbens volume confers risk for developing chr
291 or developing chronic pain exhibit a smaller nucleus accumbens volume, which persists in the chronic
293 t in CUD compared to controls, metabolism in nucleus accumbens was lower for the placebo and MPH meas
295 ifically, prediction-error activation in the nucleus accumbens was similar across age groups, and num
297 associated with anticipatory activity in the nucleus accumbens, whereas perceptual bias tracked categ
298 atients exhibited higher SERT binding in the nucleus accumbens while DAT availability in the amygdala
299 ciated with more focal hyporeactivity in the nucleus accumbens, while depression severity during earl
300 n may underlie augmented connectivity of the nucleus accumbens with fear/anxiety regions, disrupting