ライフサイエンスコーパス: nucleus basalis

1 nd and horizontal diagonal band, but not the nucleus basalis.

2 ic immunotoxin, anti-p75NTR-saporin into the nucleus basalis.

3 ppocampus (CA 2/3), and neuronal loss in the nucleus basalis.

4 l septal nucleus, the diagonal band, and the nucleus basalis.

5 reciprocal cortical projections back to the nucleus basalis.

6 th activation of cholinergic inputs from the nucleus basalis.

7 th activation of cholinergic inputs from the nucleus basalis.

8 bulb, striatum, globus pallidus, septum, and nucleus basalis.

9 Lhx8 mutants lack the nucleus basalis, a major source of the cholinergic input

10 However, the effect of nucleus basalis activation on sensory processing remains

11 Pairing sensory stimulation with nucleus basalis activation shifted the preferred stimuli

12 ameters of the acoustic stimulus paired with nucleus basalis activation.

13 neurons in the neocortex, limbic system, and nucleus basalis, among others.

14 injury, cholinergic neurons in the anterior nucleus basalis (aNB) of the basal forebrain are increas

15 including the hippocampus, caudate nucleus, nucleus basalis and cortex.

16 Neurons of the basal forebrain nucleus basalis and posterior substantia innominata (NBM

17 Rats received unilateral lesions of the nucleus basalis and were infused intracerebroventricular

18 ive cells were detected in the contralateral nucleus basalis, and in the ipsilateral and contralatera

19 storically identified as an extension of the nucleus basalis, as well as ChAT(-) cells, release the i

20 Within the nucleus basalis, choline acetyltransferase was found in

21 ces in parietal cholinergic fiber density or nucleus basalis cholinergic neuron number or volume were

22 umber ofm2-immunoreactive neurons within the nucleus basalis complex from aged controls and AD patien

23 hether pairing a tone with activation of the nucleus basalis could induce RF plasticity in the waking

24 yltransferase (ChAT)-containing cells in the nucleus basalis following a unilateral injection of ibot

25 cholinergic neurons in the medial septum and nucleus basalis from the effects of excitotoxic or mecha

26 These results strengthen the hypothesis that nucleus basalis gates neural plasticity necessary for in

27 ilateral injection of ibotenic acid into the nucleus basalis; however, these effects were not related

28 ies can also be found in the locus ceruleus, nucleus basalis, hypothalamus, cerebral cortex, cranial

29 limbic affiliation explains the role of the nucleus basalis in modulating the impact and memorabilit

30 distributed neural circuits, as evidenced by nucleus basalis-induced changes in thalamic responses.

31 omodulatory systems, such as the cholinergic nucleus basalis, interact with and refine cortical circu

32 Bilateral ibotenic acid lesions of the nucleus basalis interfered with passive avoidance and sp

33 understood, the cholinergic circuitry of the nucleus basalis is emerging as one of the most strategic

34 The nucleus basalis is located at the confluence of the limb

35 m, and cholinergic projection neurons in the nucleus basalis is observed and is ascribed to an early

36 Thus paired activation of the nucleus basalis is sufficient to induce receptive field

37 ecamylamine-sensitive manners in bilaterally nucleus basalis lesioned rats; and (3) elevate high-affi

38 New results indicate that nucleus basalis lesions prevent motor cortex map plastic

39 ocortical atrophy and degeneration following nucleus basalis lesions.

40 o detected in the striatum (4.2%) and in the nucleus basalis magnocellularis (19.2%) 3-12 h following

41 Since the Nucleus Basalis Magnocellularis (Meynert in humans and p

42 es of evidence have supported a role for the nucleus basalis magnocellularis (NB) in attentional mech

43 Rats with quisqualic acid lesions of the nucleus basalis magnocellularis (nBM) and control rats w

44 Rats with 192 IgG-saporin lesions of the nucleus basalis magnocellularis (NBM) and sham-operated

45 Previous research has demonstrated that nucleus basalis magnocellularis (nbm) corticopetal choli

46 termine if a selective cholinergic lesion of nucleus basalis magnocellularis (Nbm) could affect the n

47 s tested the hypothesis that the cholinergic nucleus basalis magnocellularis (NBM) is involved in sol

48 ic lesions of the medial septum area (MS) or nucleus basalis magnocellularis (NBM) on amplitude and p

49 ed in aging rats: cholinergic lesions of the nucleus basalis magnocellularis (NBM) produce larger dec

50 LS, animals were lesioned bilaterally in the nucleus basalis magnocellularis (nBM) using either quisq

51 of the diagonal band of Broca (HDB) and the nucleus basalis magnocellularis (NBM) were counted.

52 Fluctuations in the nucleus basalis magnocellularis (NBM) were highly variab

53 ith bilateral 192 IgG-saporin lesions to the nucleus basalis magnocellularis (nBM) were tested on olf

54 c immunotoxic- or sham-lesion surgery of the nucleus basalis magnocellularis (NBM), the basal forebra

55 F receptor immunoreactive neurons within the nucleus basalis magnocellularis (NBM), the horizontal li

56 The BLA projects to the nucleus basalis magnocellularis (NBM), which sends broad

57 ormation and its release is regulated by the nucleus basalis magnocellularis (NBM).

58 ith a 2-week-old right-sided ablation of the nucleus basalis magnocellularis (NBM).

59 A) and the cholinergic substantia innominata/nucleus basalis magnocellularis (SI/nBM) is important fo

60 A from the cholinergic substantia innominata/nucleus basalis magnocellularis (SI/nBM) on performance

61 s in the sublenticular substantia innominata/nucleus basalis magnocellularis (SI/nBM), as well as cer

62 no marked loss of cholinergic neurons in the nucleus basalis magnocellularis after intracerebroventri

63 Results demonstrated that lesions of the nucleus basalis magnocellularis and frontal cortex selec

64 ticopetal cholinergic lesions applied to the nucleus basalis magnocellularis and substantia innominat

65 as suggested that cholinergic neurons in the nucleus basalis magnocellularis and substantia innominat

66 Injection of lidocaine into the nucleus basalis magnocellularis produced a profile of be

67 Lesions of the nucleus basalis magnocellularis were without effect on t

68 nt changes in trkA mRNA were detected in the nucleus basalis magnocellularis, and no significant chan

69 rizontal limb of the diagonal band of Broca, nucleus basalis magnocellularis, and striatum of gonadec

70 h the medial septum, diagonal band of Broca, nucleus basalis magnocellularis, and striatum were proce

71 ilateral injection of ibotenic acid into the nucleus basalis magnocellularis, or unilateral transecti

72 ell bodies in the medial septal area and the nucleus basalis magnocellularis, radiofrequency lesions

73 nfusions of colchicine or vehicle in the rat nucleus basalis magnocellularis, the time course of chan

74 ved bilateral quisqualic acid lesions of the nucleus basalis magnocellularis.

75 ow-affinity p75 neurotrophin receptor in the nucleus basalis Meynert failed to reveal differences bet

76 mygdala; nucleus accumbens; ventral pallium; nucleus basalis Meynert; bed nucleus of the stria termin

77 re paired with electrical stimulation of the nucleus basalis (NB) 300 to 400 times per day for 20-25

78 cy paired with electrical stimulation of the nucleus basalis (NB) at tone offset.

79 ubstance P (SP) excites large neurons of the nucleus basalis (NB) by inhibiting an inward rectifier K

80 Degeneration of cholinergic nucleus basalis (NB) cortical projection neurons is asso

81 The nucleus basalis (NB) has been implicated in memory forma

82 The nucleus basalis (NB) in the basal forebrain provides mos

83 cholinergic innervation of the cortex by the nucleus basalis (NB) is known to modulate cortical neuro

84 The nucleus basalis (NB) mediates cortical electroencephalog

85 Cholinergic basal forebrain (CBF) nucleus basalis (NB) neurons display neurofibrillary tan

86 f acetylcholine following stimulation of the nucleus basalis (NB) of Meynert have been recently exami

87 Electrical activation of the nucleus basalis (NB) of Meynert, the source of neocortic

88 Pairing pulsed noises with nucleus basalis (NB) stimulation in awake rats for 4 wee

89 NFT evolution within the CBF neurons of the nucleus basalis (NB) using tissue from subjects with no

90 ring acoustic stimuli with activation of the nucleus basalis neuromodulatory system.

91 on of ACh release from cortical afferents of nucleus basalis neurones in vivo.

92 Both markers were expressed robustly in nucleus basalis neurons and across all three groups.

93 a indicate that alterations in the number of nucleus basalis neurons containing trkA immunoreactivity

94 T8 (or Alz-50) immunostaining in cholinergic nucleus basalis neurons existed even in the cognitively

95 ere is a marked reduction in trkA-containing nucleus basalis neurons in end-stage Alzheimer's disease

96 The percentage of tauopathy-containing nucleus basalis neurons was greater in the cognitively i

97 The number of p75(NTR)-immunoreactive nucleus basalis neurons was significantly correlated wit

98 Seventy-five days later, cholinergic nucleus basalis neurons were atrophic ipsilateral to the

99 , nucleus of the diagonal band (DB), and the nucleus basalis of Meynert (NB).

100 the medial septal/diagonal band (MS/DB) and nucleus basalis of Meynert (NBM) also reveal a selective

101 eives dense cholinergic projections from the nucleus basalis of Meynert (NBM) and the horizontal limb

102 creases in ChAT and trkA are observed in the nucleus basalis of Meynert (nBM) of both age groups.

103 In the nucleus basalis of Meynert (NBM) of middle-aged monkeys,

104 bution of these receptor subunits within the nucleus basalis of Meynert (NBM) of non-demented elderly

105 Acetylcholine neurons in nucleus basalis of Meynert (NBM) were selectively lesion

106 Dysfunction of the nucleus basalis of Meynert (NBM), a basal forebrain stru

107 vivo markers of neurodegeneration within the nucleus basalis of Meynert (NbM), a subregion of the bas

108 mine total cholinergic neuron numbers in the nucleus basalis of Meynert (nbM), stereologic methods we

109 ular cortex (IC), central amygdala (CE), and nucleus basalis of Meynert (NBM), which decomposes the a

110 The nucleus basalis of Meynert (NbM), which serves as the pr

111 ic neurons in the substantia innominate (SI)/nucleus basalis of Meynert (nBM)-medial prefrontal corte

112 o the cortex from cholinergic neurons in the nucleus basalis of Meynert (NBM).

113 of Broca (MS) and the substantia innominata/nucleus basalis of Meynert (SI).

114 r cholinergic basal forebrain nuclei CH4/4p (nucleus basalis of Meynert [NBM]) and CH1/2/3.

115 nd improved cholinergic axonal health in the nucleus basalis of Meynert akin to wildtype mice.

116 tantia nigra, raphe nuclei, locus coeruleus, nucleus basalis of Meynert and dorsal motor nucleus of v

117 ious studies have shown that the cholinergic nucleus basalis of Meynert and its white matter projecti

118 therapy (ERT) on cholinergic neurons in the nucleus basalis of Meynert and on cholinergic fibers in

119 er, how white matter projections between the nucleus basalis of Meynert and the cortex are altered in

120 Although cholinergic neurons in the nucleus basalis of Meynert are a major source of choline

121 counterpart in budgerigars of the mammalian nucleus basalis of Meynert consists of a field of cholin

122 We show that degeneration of the cholinergic nucleus basalis of Meynert in Alzheimer's disease and de

123 gnition and attention than the volume of the nucleus basalis of Meynert itself and might be an early

124 o difference in orexinergic fiber density in nucleus basalis of Meynert or locus ceruleus compared to

125 nitive impairment, loss of integrity of both nucleus basalis of Meynert pathways was associated with

126 Nucleus basalis of Meynert volume was reduced in all cli

127 minant frequency was associated with smaller nucleus basalis of Meynert volumes (beta = 0.22, P = 0.0

128 f white matter pathways originating from the nucleus basalis of Meynert was performed using diffusion

129 aphe, locus coeruleus, ventral tegmentum and nucleus basalis of Meynert, and efferent projections to

130 ntal limb of the diagonal band of Broca, the nucleus basalis of Meynert, and the inferior olivary nuc

131 l and medial septum, diagonal band of Broca, nucleus basalis of Meynert, bed nucleus of stria termina

132 limbs of the diagonal band of Broca, and the nucleus basalis of Meynert, medial habenular nucleus, zo

133 were no differences in ChAT activity in the nucleus basalis of Meynert, nor any of several neocortic

134 l motor nucleus of the vagus, but not in the nucleus basalis of Meynert, raphe nucleus, or other brai

135 primarily in subregions associated with the nucleus basalis of Meynert, suggesting that it is the ch

136 as (pedunculopontine/laterodorsal tegmentum, nucleus basalis of Meynert, thalamus, and locus ceruleus

137 ional volumetric measures of hippocampus and nucleus basalis of Meynert, using a receiver operating c

138 re most pronounced in posterior parts of the nucleus basalis of Meynert, whereas in AD, atrophy was m

139 tion is located in the Ch4 cell group of the nucleus basalis of Meynert.

140 ic fibers that originate from neurons in the nucleus basalis of Meynert.

141 l limb of the diagonal band of Broca and the nucleus basalis of Meynert.

142 ca, the magnocellular preoptic area, and the nucleus basalis of Meynert.

143 onounced cholinergic axonal swellings in the nucleus basalis of Meynert.

144 nucleus, substantia nigra, and the forebrain nucleus basalis of Meynert.

145 gradients, with the lowest tethering in the nucleus basalis of Meynert.

146 e show early degeneration of the cholinergic nucleus basalis of Meynert.

147 hippocampal volume or volume of cholinergic nucleus basalis of Meynert.

148 cked a medial and a lateral pathway from the nucleus basalis of Meynert.

149 al motor nucleus of the X cranial nerve, and nucleus basalis of Meynert.

150 ei, such as the pedunculopontine nucleus and nucleus basalis of Meynert.

151 , dorsal motor nucleus of the vagus, and the nucleus basalis of Meynert.

152 The nucleus basalis of the basal forebrain is an essential c

153 For example, the nucleus basalis of the forebrain plays a critical role i

154 diagonal band, but not in the medial septum, nucleus basalis, or striatum of females vs. males.

155 icant and similar reduction in the number of nucleus basalis p75(NTR)-immunoreactive neurons was seen

156 that episodic electrical stimulation of the nucleus basalis, paired with an auditory stimulus, resul

157 the OX-26-NGF conjugate restored the size of nucleus basalis perikarya to within normal limits relati

158 memory, area 46, and in the component of the nucleus basalis projecting to this region.

159 vealed long-range connections from thalamus, nucleus basalis, raphe, and distant cortical areas, incl

160 inergic neurons of the substantia innominata/nucleus basalis region, and their innervation of the pos

161 iagonal band (HDB) and substantia innominata/nucleus basalis (SI/NB) following ovariectomy.

162 s in the contralateral substantia innominata/nucleus basalis (SI/nBM) failed to show the enhanced att

163 ROSAB or EHD2-scTNFR2 into the magnocellular nucleus basalis significantly protected cholinergic neur

164 ecording in rat visual cortex, we found that nucleus basalis stimulation caused prominent decorrelati

165 Nucleus basalis stimulation produced electroencephalogra

166 Paired tone/nucleus basalis stimulation, but not unpaired stimulatio

167 2) located primarily outside the cholinergic nucleus basalis subfields.

168 its vehicle was infused into the area of the nucleus basalis/substantia innominata of the basal foreb

169 ty, we paired a tone with stimulation of the nucleus basalis, the main subcortical source of cortical

170 to identify pre-tangle cytopathology in the nucleus basalis, the source of cortical cholinergic inne

171 ng tones with stimulation of the cholinergic nucleus basalis to induce auditory cortex map plasticity

172 dles of cholinergic fibres extended from the nucleus basalis to the cerebral cortex and amygdala and

173 ys which link the cholinergic neurons of the nucleus basalis to the human cerebral cortex.

174 Large neurons of the cholinergic nucleus basalis together with CA1 and CA3 pyramidal neur

175 d in the olfactory bulbs, frontal cortex, or nucleus basalis/ventral pallidum following hormone treat

176 yriform cortex, olfactory bulbs, septum, and nucleus basalis/ventral pallidum were dissected.

177 projecting to this region of cortex from the nucleus basalis was also reduced by 50 +/- 6%.

178 Although nucleus basalis was stimulated only for a few minutes, r

179 Cholinergic neurons in the medial septum and nucleus basalis were detected and quantified using immun

180 to nucleus basorostralis (previously called nucleus basalis), whereas input from the rest of the bod

181 agonal band and in the posterior half of the nucleus basalis, which is where there was the greatest o

182 The anatomical continuity of the nucleus basalis with other basomedial limbic structures