ライフサイエンスコーパス: null mutant

1 down of for in pr1 cells phenocopies the for null mutant.

2 5a-CD3 can rescue the phenotype of a pcdh15a-null mutant.

3 mediated translation was reduced in an eif4g null mutant.

4 ll mutant mice, as well as in a human Nav1.7-null mutant.

5 allele of Fgfr2 that broadly phenocopies the null mutant.

6 and complement the growth of an HSV-1 ICP27 null mutant.

7 eristem activity, as observed in the clasp-1 null mutant.

8 lignant cells refractory to the gamma(1)34.5 null mutant.

9 ibed at robust levels in both H2Av and JIL-1 null mutants.

10 paired T-tubule formation, phenocopying amph-null mutants.

11 nome stability in larval neuroblasts of mps1-null mutants.

12 "obligate cheaters" quorum-sensing response null mutants.

13 fferently from previously described synthase null mutants.

14 unc-64 (C. elegans orthologue of syntaxin-1)-null mutants.

15 with the developmental delay seen in pacman null mutants.

16 mesodermal defects that phenocopy brachyury null mutants.

17 media for wild-type procyclics, but not HSK null mutants.

18 e mutual interactions are perturbed in IP6K3-null mutants.

19 embryonic lethality of GPI biosynthesis gene null mutants.

20 y phenocopied the truncation defects of Lhx1-null mutants.

21 s, whereas longevity was increased in nup100-null mutants.

22 mexicana Deltagk, Deltapepck, and Deltappdk null mutants.

23 58 were evaluated using isogenic cpb and cpe null mutants.

24 generated and characterized 2 zebrafish cbfb null mutants.

25 ion of a library of 484 transcription factor null mutants.

26 f EAL are delayed in development, similar to null mutants.

27 ings to S-starvation was compared to ggct2;1 null mutants.

28 ficient to rescue LTM defects of creb1/crh-1-null mutants.

29 nses were monitored in two independent cerk1 null mutants; a deletion mutant lacking D14L, and with D

30 We now show that Deltaafkp80(-) null mutants ablated d-Arap modifications of LPG as pred

31 iologically relevant in wild-type cells, and null mutants accumulate elevated levels of intracellular

32 ere invasive infections is the presence of a null mutant allele for the orphan kinase RocA.

33 pe CpRbp1 allele and another with the CpRbp1-null mutant allele.

34 Arabidopsis CGEP null mutant alleles (cgep) had no visible phenotype but

35 ematode C. elegans and analyze the effect of null mutant alleles of all members of the SoxB and SoxC

36 PME gene T-DNA insertion lines revealed two null mutant alleles of PME34 (At3g49220) that both consi

37 differences disappear in the presence of G9a null mutant alleles, showing that G9a is necessary for t

38 In line with this, Foxp2-null mutants also show a loss of ITCs at postnatal time

39 EPT-null mutants also show attenuated virulence in BALB/c mi

40 complete complementation of the white gun4-2 null mutant and a chlorotic phenotype comparable to gun4

41 ein analysis identified ttn(xu071) as a near-null mutant and the other six mutants as hypomorphic all

42 and heterografts of gtr1 gtr2, biosynthetic null mutant and wild-type plants indicate that S-cells a

43 generated ORF33-null, ORF38-null, and double-null mutants and found that these mutants apparently hav

44 replacement resulted in two putative CpRbp1-null mutants and genotype analyses identified these two

45 ur inability to generate L. amazonensis SODA null mutants and the lethal phenotype observed following

46 he expression of ompR was elevated in an RND-null mutant, and ompR deletion partially restored virule

47 essing strain conferred motility upon a pagM null mutant, and proteinase K treatment eliminated motil

48 and spatial learning-memory defects in Kcna1-null mutants, and (3) raise the threshold for calcium-in

49 These defects are not seen in Eaat1-null mutants, and so they cannot be explained by loss of

50 n the prothoracic gland in an otherwise kdm5 null mutant animal is sufficient to rescue both the larv

51 Fig4 null mutant animals are viable but exhibit marked enlarg

52 We found that null mutant animals invariably died at around the time o

53 short body lengths(2), capn3a-null and nid1a-null mutants appear normal.

54 NPYLR7 CRISPR-Cas9 null mutants are defective in behavioral suppression and

55 lin-28 null mutants are homozygous viable but display defects i

56 We found that rpaA-null mutants are inviable after several hours in the dar

57 vpr-1 null mutants are maternal effect sterile due to arrested

58 dicate that many synaptic defects in unc-104-null mutants are mediated independently of Unc-104's tra

59 Zebrafish scospondin-null mutants are unable to assemble a Reissner fiber and

60 Both KHAP1 and KHAP2 null mutants are unable to execute cytokinesis but are a

61 clv1 null mutants are weaker in phenotype than clv3 mutants,

62 Strip1-null mutants arrest development at midgestation with pro

63 Loss of Emb14 function in the null mutant arrests embryogenesis at the early transitio

64 Furthermore, by utilizing atslp2 null mutant, AtSLP2 complemented and AtSLP2 overexpressi

65 er AtGPA1(S52C) or AtGPA1(Q222L) in the gpa1-null mutant background revealed various mutant phenotype

66 e expression using wild-type (WT) and BRP-39 null mutant (BRP-39(-/-) ) mice.

67 repression of PXMT1 is abolished in a mir163 null mutant, but the repression can be restored to wild-

68 f zebrafish Pcdh15a (CD1 and CD3) in pcdh15a-null mutants by assessing Pcdh15a transgene-mediated res

69 tosamine containing N-glycans of the TbGnTII null mutants by methylation linkage analysis suggests th

70 Here, we show that a sec3a exocyst subunit null mutant cannot be transmitted through the male gamet

71 Nicotiana benthamiana (Nb) is a natural null mutant carrying Rcr3 and Pip1 alleles with deleteri

72 the lung phenotypes of Yap and Hippo kinase null mutants caused controversy over the dynamics and si

73 C. difficile DdlR is essential, as the ddlR null mutant cells could not grow even in complex laborat

74 n contrast, autophagosomes generated in Rab5-null mutant cells normally fuse with lysosomes during th

75 e docking defect observed previously in syt1 null mutant cells, similar to wild type Syt1 (Syt1-wt).

76 c transmission, Syt1-R398/399Q (RQ), in syt1 null mutant cells.

77 horylation is indeed compromised in the H2Av null mutant, chromatin decondensation at heat shock loci

78 he methyl-accepting chemotaxis protein (MCP)-null mutant CNB-1Delta20.

79 on and, combined with the recently completed null mutant collection, open the door for similar screen

80 otein (GFP)-labeled proteasomes in the yeast null-mutant collection.

81 genes are misregulated +/->2-fold in pacman null mutants compared to controls, in line with previous

82 M. tuberculosis expressing PPE2 and PPE2-null mutants complemented with PPE2 survived better than

83 entation experiments in a Columbia-0 ftsZ2-2 null mutant confirmed this allele as causal for the incr

84 ot incorporate choline into PC, yet the CPCT-null mutants contain similar levels of PC and PE as wild

85 ore importantly, both DeltaFgSch9 and FgHog1 null mutant (DeltaFgHog1) exhibited increased sensitivit

86 ological and transcriptomic analyses of h1.3 null mutants demonstrate that H1.3 is required for both

87 ation of flowering by NB disappeared in ppd1-null mutants, demonstrating that this response is mediat

88 ing murine palate development, and Tgf-beta3 null mutants develop cleft palate with 100% penetrance.

89 s to be an essential gene as the chromosomal null mutants did not survive.

90 ide a mechanistic explanation as to why rpaA-null mutants die in the dark, further connect the clock

91 components and FANCD2 and found that FANCD2-null mutants display higher levels of spontaneous chromo

92 The for null mutants display impaired responses to thermal nocic

93 Consistent with this, the sec-null mutant displayed reduced responses to GA and brassi

94 Single or double formin-null mutants displayed only moderate defects in cortex f

95 n was reduced by 70% in CAPS-1/CAPS-2 double null mutant (DKO) neurons and remaining fusion events re

96 Interestingly, we found that rpl15 null mutants do not complete embryogenesis, indicating t

97 SHARP1 and SHARP2 single null mutants do not display any cognitive phenotype supp

98 delayed the growth of wild-type but not sspA null mutant E. coli.

99 remodelled, we analysed the phenotype of sdk null mutant embryos during Drosophila axis extension usi

100 Finally, EDNRB-null mutant ENS precursors enable modelling of HSCR-rela

101 he wild type and in each of the single psb28 null mutants except for loss of RC47 in the absence of P

102 Both ops and brx null mutants exhibit defects in protophloem differentiat

103 is is supported by our observations that tim null mutants exhibit reduced incidence of reproductive d

104 The Pde2 null mutant exhibited a lower growth rate and increased

105 A ybtPQ-null mutant exhibited no growth defect under standard cu

106 Furthermore, PfGMD null mutant exhibited normal growth and invasion rates,

107 AvrPtoB phospho-null mutants exhibited compromised virulence functions a

108 s that can limit the infection, and an ORF52 null mutant exhibits increased cGAS signaling.

109 mplex and hybrid N-glycans, T. brucei TbGT11 null mutants expressed atypical "pseudohybrid" glycans,

110 using microarrays and PCR have shown that SM-null mutants fail to accumulate several lytic cycle mRNA

111 Recombinant ORF57-null mutants fail to accumulate several lytic cycle mRNA

112 are defective in antigen 43 production, osmY-null mutants failed to undergo cellular autoaggregation.

113 ection in the epithelium of cultured Neurog3-null mutant fetal pancreas, permitting genetic complemen

114 Here, we generated Atg9 null mutant flies and found that loss of Atg9 led to sho

115 The wdp null mutant flies show a specific defect (supernumerary

116 the food overconsumption phenotype of piezo-null mutant flies.

117 NF and FW) were unable to complement an ICP8-null mutant for growth and replication compartment forma

118 GS proteins, as well as against the cysteine-null mutants for 10 of these proteins.

119 Null mutants for GCS (designated 'gcs-1') were viable as

120 iso4G in plant growth was investigated using null mutants for the eIF4G isoforms in Arabidopsis.

121 iddle, and late stages of differentiation of null mutants from the B. subtilis ordered knockout colle

122 Despite seedling lethality in the null mutant, GCS RNAi suppression lines with </=2% of wi

123 HSK null mutants generated in bloodstream forms displayed no

124 Significantly, a lmxgt1 null mutant, grown in abundant glucose, undergoes catast

125 A strain defective in all four systems (null mutant) had a severe growth defect under aerobic co

126 A pix-1 null mutant has a reduced level of activated Rac in musc

127 The schA null mutant has increased and decreased trehalose and gl

128 Additionally, zebrafish kmt2d null mutants have angiogenesis defects depicted by abnor

129 Whereas rnc3 and rnc4 null mutants have no visible phenotype, rnc3/rnc4 (rnc3/

130 We demonstrate that zebrafish kmt2d null mutants have robust Notch signaling hyperactivation

131 Patch-clamp physiology in conditional null mutant hippocampal neurons expressing Cre and eithe

132 plex, increases the replication of both ICP0-null mutant HSV-1 and pp71-deficient HCMV.

133 -LP, which targets Sp100, also augments ICP0-null mutant HSV-1 replication.

134 on of PIAS4 enhances the replication of ICP0-null mutant HSV-1, which is susceptible to restriction b

135 1 and pp71 stimulate the replication of ICP0-null mutant HSV-1, while ICP0 increases plaque formation

136 together, almost completely complement ICP0 null mutant HSV-1.

137 vity of the wt protein in complementing ICP0 null mutant HSV-1.

138 trioles in delta-tubulin and epsilon-tubulin null mutant human cells lack triplet microtubules and fa

139 may not replicate the analgesic phenotype of null mutant humans and mice, but may be potentiated with

140 ly higher than TG latently infected with LAT-null mutant (i.e., LAT(-)TG).

141 ransgenic rabbits latently infected with LAT-null mutant (i.e., LAT(-)TG).

142 stress and this ability is impaired in TgVP1 null mutants implicating TgVP1 in osmoregulation.

143 We found that a null mutant in aafA, the major subunit of AAF/II, adhere

144 d virions, we assessed infectivity of the gH-null mutant in diverse mammalian cell types in vitro Unl

145 We isolated an Eh null mutant in Drosophila and used it to investigate the

146 In contrast, a null mutant in gamma34.5 failed to control IRF3 phosphor

147 donor is used in vivo, we generated an otsA null mutant in S. venezuelae The mutant had a cell densi

148 2's function was characterized by generating null mutants in C. neoformans.

149 Null mutants in creb1/crh-1 are defective in LTM formati

150 ole of c-di-AMP in S. pyogenes, we generated null mutants in each of these proteins by gene deletion.

151 underscores the importance of employing true null mutants in genetic complementation studies.

152 In addition, null mutants in GRX6 display a more intense unfolded pro

153 lemented with PPE2 survived better than PPE2-null mutants in infected RAW 264.7 macrophages.

154 n in intact parasites, we generated Deltaarg null mutants in L. donovani and evaluated their ability

155 plementation test with CRISPR/Cas9-generated null mutants in nonstandard wild accessions.

156 and our data support the idea of their being null mutants, in contrast to previously described transc

157 and restores motility in the paralyzed sfpq null mutants, indicating a non-nuclear processing role i

158 by genetically correcting Wg levels in Notum null mutants, indicating that Notum normally functions t

159 eproduced the neonatal lethality observed in null mutants, indicating that the defective diaphragm is

160 In foxc1a null mutants, instead of converging with other nerves at

161 Intravaginal inoculation of the TC0668 null mutant into C3H/HeJ mice results in a typical cours

162 An mntR null mutant is highly sensitive to Mn(II) intoxication,

163 miR-274 expressed in glia of an mir-274 null mutant is released as an exosomal cargo in the circ

164 Here, we show that an mntR null mutant is still sensitive to Mn(II) intoxication ev

165 ity remaining in the sperm of CAII- and CAIV-null mutants is 35% and 68% of that found in WT mice.

166 nd mitochondria, but embryo lethality of gr2 null mutants is caused specifically in plastids.

167 Pol I transcription in hpr1 or tho2 null mutants is dramatically reduced to less than 20% of

168 In dectin-1-null mutant (knock-out) mice, dieback of corticospinal t

169 In this study, we generated a gH-null mutant KSHV and provided evidence that deficiency o

170 In a null mutant, lack of IFT74 destabilized IFT-B, leading t

171 In obst-A null mutant larvae, the assembly zone is strongly dimini

172 Here, we demonstrate that aged Gal1-null mutant (Lgals1 (-/-) ) mice develop a spontaneous i

173 Genetically modified variants of the null mutant line were subsequently used to establish the

174 ting light intensities, the Arabidopsis MET1 null mutant (met1) showed conditional reduced growth, ne

175 We studied dysbindin-1 null mutant mice (Dys(-/-)) to shed light on retinal neu

176 Constitutive Lpar1 null mutant mice are protected from partial sciatic nerv

177 Constitutive Lpar1 null mutant mice have been instrumental in identifying r

178 d both heterozygous and homozygous D252H and null mutant mice using behavioural and motor phenotyping

179 Finally, whereas SLC10A4 null mutant mice were slightly hypoactive, they displaye

180 In the retina of Spata7 null mutant mice, a substantial reduction of RPGRIP1 lev

181 ces analgesia in both female and male Nav1.7-null mutant mice, as well as in a human Nav1.7-null muta

182 al osteoclast impairment also occurs in Msx2 null mutant mice, which is restored by overexpression of

183 and in prostate tumors of Pten/Trp53 double-null mutant mice.

184 ocyte and osteoblast differentiation in Spop-null mutant mice.

185 ies have shown severe dental defects in DSPP-null mutant mice.

186 of reduced CYFIP2 expression in heterozygous null mutant mice.

187 involution and breast tumorigenesis in Snai2-null mutant mice.

188 airway contraction are abolished in Mrgprb2-null mutant mice.

189 Ubqln2-linked ALS and also generated Ubqln2 null mutant mice.

190 Dot1l is an essential gene, as homozygous null mutant mouse embryos exhibit multiple developmental

191 Our strategy to generate null mutant mouse ES cells is applicable to thousands of

192 rtially restore islet development in Neurog3-null mutant mouse pancreata.

193 eneration of an Lpar1(flox/flox) conditional null mutant mouse that allows for cre-mediated condition

194 Using a CaMKIV null mutant mouse, we demonstrate that a loss of CaMKIV

195 A T-DNA-tagged null mutant mtppt-1 allele shows an embryo-lethal phenot

196 etion of myozap in vivo, we generated myozap-null mutant (Mzp(-/-)) mice.

197 Moreover, a CDR6/ROA1 null mutant, NKKY101, displayed increased susceptibility

198 allowed the fungus to maintain lethal CpRbp1-null mutant nuclei.

199 A null mutant of 3-hydroxyisobutyryl-CoA hydrolase (CHY4,

200 4,5), provided a means of generating an ftsZ null mutant of Escherichia coli.

201 e phenotypes were distinct from those of the null mutant of GdpP, suggesting that Pde2 and GdpP play

202 oposide or infected by an E1B 55-kDa protein-null mutant of human adenovirus type 5 carry a large num

203 ulted in an embryo lethal phenotype, while a null mutant of methylmalonate semialdehyde dehydrogenase

204 is study, we characterized cold tolerance of null mutant of RNA-DIRECTED DNA METHYLATION 4 (RDM4), wh

205 Phenotypes in the seipin-null mutant of Saccharomyces cerevisiae include aberrant

206 of Na(+)-dependent H(+) efflux in a Deltanhx null mutant of Saccharomyces cerevisiae.

207 An isogenic codY-null mutant of SM101 showed decreased levels of spore fo

208 For this study, we created an RNase III null mutant of Streptococcus pyogenes and its RNA sequen

209 of a dynein-dynactin-Spindly complex, and a null mutant of the dynactin pointed-end subunit p27 prev

210 A double null mutant of the two Arabidopsis RanGAP homologs is ga

211 Null mutants of "super-rogue" psbA4 genes, divergent par

212 Screening of null mutants of 33 of those transcription factors identi

213 Null mutants of bciD, which encodes a putative radical S

214 Null mutants of numb or the alpha-subunit of Adaptor Pro

215 The null mutants of PRRs display much reduced sensitivities

216 Null mutants of SCY2 in Arabidopsis (Arabidopsis thalian

217 n patterns varied significantly between codY-null mutants of SM101 and CN3718.

218 , where GnTII activity is essential, TbGnTII null mutants of T. brucei grow in culture and are still

219 nd the analysis of forebrain-specific double null mutants of the Insulin and IGF1 receptors revealed

220 alcium-mediated signalling, but abolished in null mutants of the pH-responsive transcription factor P

221 Null mutants of these were each combined with seven sync

222 ocytosis in Leishmania, we tried to generate null-mutants of LdRab5a and LdRab5b parasites, but both

223 In contrast to pleiotropic null mutants, only pollen numbers are significantly affe

224 l death were drastically reduced in the OXI1 null mutant (oxi1) and in the double mutant ch1*oxi1 com

225 severe arrhythmic phenotype compared to Pdf-null mutants (Pdf(01)).

226 d explains the aetiology of the even-skipped null mutant phenotype.

227 failed to recapitulate the single or double null mutant phenotypes.

228 lly correspond to severe loss of function or null mutant phenotypes.

229 btained after cenh3 L130F-complemented cenh3-null mutant plants were crossed with wild-type A. thalia

230 ssion of pollen-differentiation genes, paps1 null-mutant pollen shows a strong overaccumulation of tr

231 observe that T-cell-deficient (nude and Rag1-null mutant) pregnant mice do not exhibit pregnancy anal

232 The DacA null mutant presented a growth defect that manifested th

233 A gE-null mutant produced enveloped virions, but these accumu

234 single and higher-order T-DNA insertion jaz null mutants provided further evidence that JAZ13 is a r

235 Lep(I14) rats recapitulate phenotypes of Lep-null mutant rats including obesity, hyperinsulinemia, he

236 Drosophila CaMKII-null mutants remain viable throughout development, enabl

237 e and plant knockout models, Drosophila Ime4-null mutants remain viable, though flightless, and show

238 s of LPG as predicted, whereas Deltafkp40(-) null mutants resembled wild type (WT).

239 ed that the expression of MCP2901 in the MCP-null mutant restored chemotaxis toward nine tested aroma

240 Surprisingly, passage of the null mutant resulted in rapid outgrowth of syncytial (Sy

241 slow aerobic growth of the Rcf1/Rcf2 double null mutant results from diminished generation of mitoch

242 Generation of molecularly defined null mutants revealed that loss of 8 out of 13 JmjC gene

243 ared the mRNA profiles of wild-type and lec1-null mutant seeds at several stages of development to de

244 In contrast, Nav1.8-null mutant sensory neurons show no upregulated Penk mRN

245 The DeltaschA null mutant showed increased phosphorylation of SakA, th

246 Moreover, the ful2-null mutant showed more florets per spikelet, which toge

247 An RsbU null mutant showed severe growth defects which could be

248 an Arabidopsis (Arabidopsis thaliana) tip1;1 null mutant showed that resistance to TYLCV is severely

249 nslation in vivo and in vitro hrp38 and Parg null mutants showed an increased ectopic Nanos translati

250 indeterminate and single vrn1-null and ful2-null mutants showed delayed formation of the terminal sp

251 ent Arabidopsis (Arabidopsis thaliana) cepr1 null mutants showed disproportionately large reductions

252 lization of the ClpPR complex, whereas clpt2 null mutants showed only marginal destabilization.

253 levels of GPI-anchored glycoconjugates, SMT-null mutants showed significantly attenuated virulence i

254 In contrast, Ascl-1(null) mutants showed reduced neurogenesis for both vomer

255 xplants and mouse embryonic fibroblasts from null mutants shows that the mesoderm migration defect is

256 eted, whereas in the csr-1 partially rescued null mutant strain (WM193), this mark is ectopically dep

257 gene expression decreased in the CN3718 codY-null mutant strain but significantly increased in the SM

258 vity, because killed bacteria and a protease-null mutant strain of S. aureus were unable to penetrate

259 ut significantly increased in the SM101 codY-null mutant strain, demonstrating CodY-dependent regulat

260 Unc13A(null) mutants suffered from inefficient, delayed and EGT

261 he same sensitivity toward the wild-type and null mutants suggesting its effect is not through bindin

262 nconi anemia complementation group L (FANCL)-null mutants, suggesting that FANCD2 provides a basal le

263 le of rescuing filopod formation in the myo7-null mutant, supporting fundamental functional conservat

264 r mammalian Piezo1 in these neurons of piezo-null mutants suppresses the overconsumption phenotype.

265 lar distribution of an overexpressed phospho-null mutant, TH1-S31A, was restricted to the soma of neu

266 generated and characterized zebrafish kmt2d null mutants that recapitulate the cardinal phenotypic f

267 Here, using single- and double-null mutants, the constitutively synthesized ERF-VIIs RE

268 further dissected, we need a precise genetic null mutant to definitively map its amorphic phenotypes.

269 erved that photosynthesis in the Arabidopsis null mutant tpk3-1, which carries a transfer DNA inserti

270 Here, we show that pancreas-specific Hnf1a null mutant transcriptomes phenocopy those of Kdm6a muta

271 While the null mutant used heme as an iron source in vitro, we dem

272 ycle, we engineered a recombinant KSHV ORF52-null mutant virus and found that loss of ORF52 results i

273 ed electron microscopy to reveal that the gH-null mutant virus assembled and exited from cells normal

274 Surprisingly, ICP0-null mutant virus yields decreased upon TRIM27 depletion

275 in cells infected with a newly isolated UL32-null mutant virus, suggesting that UL32 acts as a chaper

276 allenged with the wild type (W83) and the SL-null mutant (W83 DeltaSPT), the SL-null strain elicited

277 In support of this, the null mutant was only moderately attenuated in an infant

278 The schA null mutant was sensitive to rapamycin, high concentrati

279 e virus or a gH-containing revertant, the gH-null mutant was unable to infect any of the epithelial,

280 A newly generated UL32-null mutant was used to confirm that although B capsids

281 echanistic basis for nanI expression, a nanR null mutant was used to demonstrate that NanR, a member

282 By analyzing Ascl-1(null) mutants we dissociated the neurogenic defects obse

283 Using the gH-null mutant, we showed that gH was indispensable for KSH

284 3 present in cells infected by an E1B 55-kDa-null mutant were similar.

285 This was challenged by observations that gO-null mutants were defective on all of these cell types,

286 In addition, nine Bacillus subtilis PBP-null mutants were evaluated with the goal of identifying

287 Previously, imaA-null mutants were found to induce an elevated inflammato

288 SMT-null mutants were fully viable and replicative in cultur

289 ulence of S. pyogenes, as both DacA and Pde2 null mutants were highly attenuated in a mouse model of

290 The TgVP1 null mutants were more sensitive to extracellular condit

291 hat the mutant phenotypes of prc1-1, a cesa6 null mutant, were rescued by the chimeric CESA5, and bec

292 owever, when expressed in an Arabidopsis phy-null mutant, wheat PHYC forms signaling active homodimer

293 restore proper symbiotic features in a symrk null mutant where rhizobial invasion of the epidermis an

294 ygosity with ABCB4(A286V), ABCB4(A953D), and null mutants, whose symptoms cover the spectrum of chole

295 P tagging by CRISPR-Cas9 or with rescue of a null mutant with a GFP fusion, this approach enables rou

296 ons, we transformed the embryo-lethal tps1-1 null mutant with various forms of TPS1 and with a hetero

297 s T-DNA insertion mutants were identified as null mutants with early embryonic lethal phenotypes that

298 Phosphoproteomic comparison of TbDYRK null mutants with wild-type parasites identified molecul

299 omplete, as F0 embryos closely resemble true null mutants without detectable non-specific effects.

300 ical analyses of Rcf1/Rcf2 single and double null-mutant yeast cells and mitochondria, we further exp