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1 systems with complex dynamics and/or a small number of molecules.
2 ics where it is mandatory to analyze a great number of molecules.
3 r when experiments are started from a finite number of molecules.
4 ow in aligning long molecules and/or a large number of molecules.
5 ue combinations of reactions between a fixed number of molecules.
6 ds rely on averaged information over a large number of molecules.
7 rtificially limit the description to a small number of molecules.
8 microscopy experiment involving an arbitrary number of molecules.
9 s of complexity also imply different overall number of molecules.
10 on is therefore typically limited to a small number of molecules.
11 ly expensive for a system comprising a large number of molecules.
12 ochastic assignment of the bonds to a finite number of molecules.
13 ons regarding the ensemble behavior of large numbers of molecules.
14 l studies of electron transfer through small numbers of molecules.
15 ns, which is important when there are finite numbers of molecules.
16 sing measurements of fluorescent proteins in numbers of molecules.
17 omains have different diameters or different numbers of molecules.
19 en there will be a transient increase in the number of molecules activated by the other growth factor
20 scaling behavior in the distribution of the number of molecules after a given number of PCR cycles a
21 -analysis for the measurement of the average number of molecules and brightness in each pixel in fluo
22 cuit is assembled using a relatively limited number of molecules and common developmental steps, from
25 capture pathway activity due to the limited number of molecules and incomplete pathway coverage comp
27 volume contains a statistically large enough number of molecules and is above the Poisson noise limit
30 is capable of measuring the apparent average number of molecules and their oligomerization (brightnes
32 roperties of complexes containing very large numbers of molecules and extends the condensed complex m
33 ics of transcriptional control involve small numbers of molecules and result in significant fluctuati
34 on when experiments are started from a large number of molecules, and we derive an upper bound for th
35 al processes operate with surprisingly small numbers of molecules, and there is renewed interest in a
36 idual cell involves reactions between finite numbers of molecules, and this can result in inherent ra
37 sease correlated features early before large number of molecules are impacted by disease progression
39 Biochemical reactions that involve small numbers of molecules are intrinsically noisy, being domi
42 t SNAP25, SCORE2 allows determination of the number of molecules at fusion sites and the number that
43 ound antibodies/Fab is used to determine the number of molecules attached to viral HA while a fluores
45 cted for "synthesis." Beginning with a small number of molecules, based only on structures and activi
48 ss of the side group chemical nature and the number of molecules bound, the space adjacent to the 369
49 emical space can generate an almost infinite number of molecules, but exploration of known molecules
50 chemistry has given chemists access to vast numbers of molecules, but selecting the right one has pr
51 anelles as well as accurately count absolute numbers of molecules, by correcting for undercounting ow
52 o estimate photoswitching rates, the unknown number of molecules can be accurately recovered from the
53 tworks and reveal how low intracellular copy numbers of molecules can fundamentally limit the precisi
54 erein, we show that for the past decade, the number of molecules claimed in patent records by major p
55 onoxide ([(11)C]CO) has been used to label a number of molecules containing a carbonyl derivative, su
58 -flight spectral acquisition and the average number of molecules desorbed per laser ablation are dete
59 tion due to technical factors, including the number of molecules detected in each cell, which can con
60 reversibility states that at equilibrium the number of molecules entering a state by a given path mus
62 observed fluctuations are not due to the low number of molecules expressed from a gene per se but ori
63 n achieve linear scaling with respect to the number of molecules for a dilute solution under VSC by a
66 of siRNA, allowing the employment of a fewer number of molecules for the inhibition of multiple targe
69 due to slow operator fluctuations and small numbers of molecules further contributes toward the shri
70 ely recovered from the posterior mode of the number of molecules given the number of localizations.
79 ure)), and thiophosphorylation increased the number of molecules having separated heads (energy advan
81 activate the mucosal epithelium to release a number of molecules impacting the activity of resident i
82 nd parallel changes in gene expression for a number of molecules important in epileptogenesis and sug
85 aled the mass per unit length, and hence the number of molecules in cross-section, along the entire l
86 +/- 71 A(3) at 25 degrees C, from which the number of molecules in each aggregate was estimated to b
88 t these predictions and to determine how the number of molecules in Nck aggregates and the density of
89 gnatures relating to the fluctuations of the number of molecules in resonance led to the attainment o
91 of aggregation and the determination of the number of molecules in the aggregate have been difficult
92 disorder, space group diversity, and varying number of molecules in the asymmetric unit occurring wit
93 ce is dependent on the training dataset, the number of molecules in the candidate set and candidate s
94 show how cross-sectional mass, and hence the number of molecules in the cross-section, depend on axia
95 expression for the PCH as a function of the number of molecules in the excitation volume is derived.
96 formation or electrode contact geometry, the number of molecules in the junction or dynamic effects m
97 ltaR in R: namely, deltaN (deviations in the number of molecules in the junction), deltaepsilon (devi
99 vice performance is determined mainly by the number of molecules in the storage media and not by thei
101 cently multi-analyte panels to study a large number of molecules in well characterized cohorts have b
102 ped a system to reversibly encapsulate small numbers of molecules in an array of nanofabricated "dimp
105 ue on crystalline model compounds with known numbers of molecules in the asymmetric unit cell, and sh
106 e SpoIIIE complexes with approximately equal numbers of molecules in the mother cell and the forespor
108 uces the rapid tyrosine phosphorylation of a number of molecules, including the cognate receptors, JA
110 es to generate insights related to the large number of molecules, inside and outside invading cells,
111 semblies that are made of a relatively small number of molecules, interconverting in dynamic equilibr
112 present in the TCR complex, we report that a number of molecules involved in downstream signaling eve
113 erived from murine bone-marrow precursors, a number of molecules involved in intracellular traffickin
114 ors controlling transcription, yet the small number of molecules involved in these pathways fluctuate
116 ic models to predict that variability in the numbers of molecules involved in upstream processes, suc
117 a considerable challenge owing to the large numbers of molecules involved, their combinatorics and t
118 that the inclusion of Se motifs into a great number of molecules is a promising strategy for obtainin
119 lular biochemical reaction systems where the numbers of molecules is small, significant noise is asso
121 hampered by noise due to undersampling: The number of molecules known to be active or inactive is va
122 The coefficient of variation then, for the number of molecules M estimated from a given number of b
124 that these networks exhibit due to the small number of molecules; moreover, they may even miss descri
125 n counts with the brightness epsilon and the number of molecules N in the optical observation volume
126 This formalism accommodates an arbitrary number of molecules N, excitations and internal vibronic
128 tivity than currently available, in terms of numbers of molecules needed for unambiguous detection.
129 lecules were readily analyzed, and the large number of molecules observed provided excellent statisti
130 nteraction with syntaxin1, with a small mean number of molecules observed to reside under membrane re
131 eport a method to conveniently determine the number of molecules of any Halo-tagged protein in the ce
136 an increase in the ATP:2e- ratio, i.e., the number of molecules of MgATP hydrolyzed for each electro
137 Of particular significance is the higher number of molecules of PBP 2 and 3 observed, since these
138 o analyze tumor responses by determining the number of molecules of RG7787 internalized per cell in v
142 efore as well as after therapy, and the high number of molecules of TNF-alpha mRNA present in the tis
143 s scaled up by proportionally increasing the numbers of molecules of all species and the reaction rat
144 tion of stochastic fluctuations due to small numbers of molecules of CREB1 and CREB2 revealed a bimod
146 nd its various components, we determined the numbers of molecules of hTR and hTERT mRNA, and the leve
149 ores, with the aim of quantifying either the number of molecules or the distribution of fluorescent l
151 ata, can significantly overestimate the mean number of molecules, overestimate extrinsic noise but un
152 rotein production occurs in bursts, with the number of molecules per burst following an exponential d
153 e neurological problems, suggesting that the number of molecules per cell must be precisely regulated
154 hat fibrin fibers are fractals for which the number of molecules per cross section increases as about
155 found that the light intensity, and thus the number of molecules per cross section, increases as I ap
158 an be neglected (often in the limit when the number of molecules per photon mode is large), we show t
159 rameters of the model are fitted, namely the number of molecules per site n, the maximum response RM
163 overlap, existing solutions to determine the number of molecules present and their precise three-dime
165 ata, this quantity is similar to the minimum number of molecules present in a single particle of infe
166 e determination (without calibration) of the number of molecules present in the flow cell in the abse
167 echanism of action of tPA is affected by the number of molecules present with respect to fibrin fiber
168 a, regardless of overlap, could increase the number of molecules processed per frame and thereby acce
169 obial pathogenesis studies have identified a number of molecules produced by ETEC that contribute to
170 modify odor representations by affecting the number of molecules reaching different receptors during
172 r release, are quantitative in measuring the number of molecules released and can be used for quantit
173 s probe volume, we could calculate the total number of molecules released from the vesicle using a th
174 sites with respect to the receptors, (2) the number of molecules released, (3) the diffusional rate a
175 de C. elegans have led to the discovery of a number of molecules required for synapse patterning and
176 ons, and blindness in the tropics, release a number of molecules, some of which appear to be immunomo
177 affected by stochastic noise, due to the low number of molecules taking part in certain reactions.
179 the time following the adsorption and on the number of molecules that adsorb to the nanowire films at
180 b')2 molecules could not explain the reduced number of molecules that bound per platelet compared to
181 Recent biochemical research has identified a number of molecules that can bind directly or indirectly
182 Furthermore, spatial separation limits the number of molecules that can physically interact, requir
183 acids exist in a dynamic equilibrium with a number of molecules that constantly interact with them a
185 cosylated by peptide N-glycanase and a large number of molecules that had not been previously glycosy
187 ibute to TGF-beta1 activation and identify a number of molecules that may participate in the process.
188 lus, the 19-kDa lipoprotein is only one of a number of molecules that mediate the innate response to
189 also focus attention upon a relatively small number of molecules that might warrant further biochemic
192 ent or sporadic emergence), and the absolute number of molecules that the mutations activate, alone o
193 ming evident that neurons express an unusual number of molecules that were originally thought to be s
194 han 11 orders of magnitude and distinguished numbers of molecules that differed by as little as 10%.
198 , this same stochasticity makes counting the number of molecules to high precision extremely challeng
199 e or cell damage, and can deliver a discrete number of molecules to the cell's interior without the r
201 ce to another, and blasting is to reduce the number of molecule tokens by drug tokens in a molecule n
202 niques, looking at average behaviors of vast numbers of molecules under conditions usually remote fro
204 to stochastic noise differs, and a critical number of molecules was required to sustain the HIGH sta
205 esented approaches to the detection of small numbers of molecules was evaluated using highly diluted
206 eyond the chiral characterization of a large number of molecules (which inevitably leads to ensemble
208 wever, quantitative analysis of the absolute number of molecules within a complex (known as stoichiom
209 cting with the endothelium predicts that the number of molecules within bonding range should decrease
211 the histogram completely, namely the average number of molecules within the observation volume and th