ライフサイエンスコーパス: nystagmus

1 ung patients or patients with high-amplitude nystagmus).

2 ea (predicting idiopathic or manifest latent nystagmus).

3 Presenting symptoms were poor fixation and nystagmus.

4 similar children with unassociated infantile nystagmus.

5 elated to four-muscle tenotomy procedure for nystagmus.

6 ant etiological factor in the development of nystagmus.

7 ection/inhalation are mydriasis, miosis, and nystagmus.

8 intellectual disability, hypotonia, ataxia, nystagmus.

9 ity of the eyes that characterizes infantile nystagmus.

10 owards the fixing eye in order to dampen the nystagmus.

11 acuity in primary position for patients with nystagmus.

12 improved target acquisition in patients with nystagmus.

13 ical features included severe spasticity and nystagmus.

14 om it seems to reduce slow-phase velocity of nystagmus.

15 nset of night blindness and hyperopia but no nystagmus.

16 cuity in achiasma or patients with infantile nystagmus.

17 even in individuals with poor VA or intense nystagmus.

18 determine the underlying cause of infantile nystagmus.

19 ntly advanced our understanding of infantile nystagmus.

20 possibility of retinal miswiring leading to nystagmus.

21 dheld OCT can predict future VA in infantile nystagmus.

22 in understanding the aetiology of infantile nystagmus.

23 osis of conditions associated with infantile nystagmus.

24 ity, 8 (42%) had strabismus, and 5 (26%) had nystagmus.

25 y is the result of retinal image motion from nystagmus.

26 ficantly higher prevalence of strabismus and nystagmus.

27 ho underwent surgery for AHP associated with nystagmus.

28 d that defects in this interaction result in nystagmus.

29 us and 4 were diagnosed with manifest latent nystagmus.

30 cataracts, microcornea, corneal opacity and nystagmus.

31 ard and rightward slow phases of optokinetic nystagmus.

32 ll affected members had periodic alternating nystagmus.

33 ulatta) during the slow phase of optokinetic nystagmus.

34 on the semicircular canal cupula, leading to nystagmus.

35 ce to the retina with a cherry red spot, and nystagmus.

36 ra-cerebellar symptoms such as imbalance and nystagmus.

37 onsidered as treatment for acquired forms of nystagmus.

38 One dog had intermittent nystagmus.

39 fined and homogeneous group of patients with nystagmus.

40 walking capability through adulthood, and no nystagmus.

41 ity reduction observed in isolated infantile nystagmus.

42 All patients had reduced vision and nystagmus.

43 families with X-linked idiopathic congenital nystagmus.

44 e reliable detection of artificially induced nystagmus.

45 nd presents as conjugate horizontal pendular nystagmus.

46 orse vision; 60% had strabismus; and 22% had nystagmus.

47 ft velocity, frequency, and intensity of the nystagmus.

48 n [SD] refractive error, -6.71 [-4.22]), and nystagmus.

49 cterized by paroxysmal attacks of ataxia and nystagmus.

50 bia, reduced visual acuity, high myopia, and nystagmus.

51 red interviews conducted with 21 people with nystagmus.

52 e: confusion, ataxia, and ophthalmoplegia or nystagmus.

53 ifts of the eyes with consequent gaze-evoked nystagmus.

54 7 items were administered to 206 people with nystagmus.

55 (2.8% in control group) and 11 of 301 (3.7%) nystagmus (0.004% in control group).

56 , 2.3%; diplopia, 2.2%; amblyopia, 0.9%; and nystagmus, 0.2%).

57 +/-SEM) was normal, 0.73; isolated infantile nystagmus, 0.80 +/- 0.11; albinism, 0.80 +/- 0.11; aniri

58 airment due to presenting visual acuity were nystagmus (14%), amblyopia (24%) and uncorrected refract

59 Forty-two patients with infantile nystagmus (19 with albinism, 17 with idiopathic infantil

60 Twenty-two had isolated infantile nystagmus, 21 had albinism, 7 had aniridia, and 7 had mi

61 her developed intractable epilepsy (7/7) and nystagmus (6/6) with increasing age.

62 Nystagmus (64%), strabismus (52%), macular degeneration

63 ncluded peripheral retinopathy (8/12 [67%]), nystagmus (8/12 [67%]), strabismus (5/12 [42%]), and opt

64 Acquired nystagmus, a highly symptomatic consequence of damage to

65 may be associated with bilateral horizontal nystagmus, a subtype of fusion maldevelopment nystagmus

66 changes in centralisation with the expanded nystagmus acuity function (NAFX) and compared with ERG r

67 ts correlation with the established expanded nystagmus acuity function (NAFX), and its test-retest va

68 oveation characteristics (using the eXpanded Nystagmus Acuity Function).

69 chieving a much clearer picture of infantile nystagmus aetiology in the future.

70 A clinical subpanel of genes for nystagmus/albinism was utilised and likely causal varian

71 bute to visual acuity loss in Down syndrome, nystagmus alone could account for most of the visual acu

72 Up to 64% of all patients with nystagmus also present strabismus, and even more patient

73 se (IRD) associated with severe visual loss, nystagmus, amaurotic pupils, oculo-digital sign and mark

74 At last visit, 6 of 27 (22%) patients had nystagmus and 12 of 20 (60%) bilaterally salvaged patien

75 patients, 12 were diagnosed with idiopathic nystagmus and 4 were diagnosed with manifest latent nyst

76 th four subjects having severe motor delays, nystagmus and absent head control, and one individual sh

77 ive eye movement recordings of patients with nystagmus and an eccentric face turn who had undergone t

78 reduced by 1.2 octaves in isolated infantile nystagmus and by 1.7 to 2.5 octaves in nystagmus with as

79 d, as measured by the clinical appearance of nystagmus and by quantitative measurement using the NAFX

80 perspectives and concerns of those who have nystagmus and can be used to determine the impact of nys

81 r motility dysfunction consisting of central nystagmus and diplopia.

82 pearance during second decade, late onset of nystagmus and dyschromatopsia (after 20 years) and prese

83 sorder in humans, characterized by infantile nystagmus and foveal hypoplasia.

84 aze-evoked horizontal or positional downbeat nystagmus and impaired vestibulo-ocular reflex suppressi

85 f acuity in patients with isolated infantile nystagmus and infantile nystagmus associated with a visu

86 se idiopathic infantile periodic alternating nystagmus and may affect neuronal circuits that have bee

87 r hypomyelinating disorders, with congenital nystagmus and mild motor delay.

88 We used the optokinetic nystagmus and pupil size to objectively and continuously

89 aracterized by color blindness, photophobia, nystagmus and severely reduced visual acuity.

90 ophthalmology department; (2) prevalence of nystagmus and strabismus at presentation in the study gr

91 ressure sensor, makes magnetic-field-induced nystagmus and vertigo possible.

92 irst, a seven month old male, presented with nystagmus and was found to have a serous RD and a tessel

93 C-terminal CASK mutations also present with nystagmus and, strikingly, we show that these mutations

94 with albinism, 17 with idiopathic infantile nystagmus, and 6 with achromatopsia) were examined.

95 Some 50% had nystagmus, and 69% of those currently aged </=16 years w

96 d 10 months-14 years) with Down syndrome and nystagmus, and a control group of 93 age-similar childre

97 ptometry, pupillometry, electroretinography, nystagmus, and ambulatory behaviour).

98 r alterations such as ptosis, hypertelorism, nystagmus, and chorioretinal coloboma.

99 terized by night blindness, photophobia, and nystagmus, and distinctive electroretinographic features

100 patients had myopia, reduced central vision, nystagmus, and electroretinographic evidence of ON bipol

101 ities in 50% including impaired convergence, nystagmus, and lid or pupil abnormalities.

102 spastic paraplegia, intellectual disability, nystagmus, and obesity (SINO).

103 ion, reduced visual acuity and color vision, nystagmus, and photoaversion.

104 s, such as baclofen for periodic alternating nystagmus, and repositioning for benign paroxysmal posit

105 ly in limb spasticity, cognitive impairment, nystagmus, and spastic urinary bladder of varying severi

106 of the abnormal head position associated to nystagmus, and to describe our treatment strategies.

107 eye orientation (suppression of spontaneous nystagmus) appear to be necessary by not sufficient cond

108 ead pitch on vertigo and previously reported nystagmus are consistent with both effects being driven

109 Mechanisms underlying infantile nystagmus are unclear.

110 ta, we hypothesize that periodic alternating nystagmus arises from instability of the optokinetic-ves

111 Isolated vertigo with horizontal positional nystagmus as an impending sign of a central lesion has r

112 otations), including the gradual decrease in nystagmus as the set point changes over progressively lo

113 h isolated infantile nystagmus and infantile nystagmus associated with a visual sensory defect.

114 Here, we investigated whether nystagmus associated with congenital stationary night bl

115 types of nystagmus, in declining order, were nystagmus associated with retinal/optic nerve disease in

116 Idiopathic and nystagmus associated with retinal/optic nerve disease we

117 A) were analyzed, and rate of strabismus and nystagmus at last follow-up visit were calculated.

118 e main outcome measure was mean intensity of nystagmus at the null region viewing at 1.2 m.

119 f nystagmus were present; three cases lacked nystagmus at the time of assessment.

120 presentation that often includes early-onset nystagmus, ataxia and spasticity and a wide range of sev

121 the FRMD7 group had AHPs, their amplitude of nystagmus being lower in primary position.

122 patients presenting with hypotonia, ataxia, nystagmus, breathing abnormalities and developmental del

123 en to be an effective procedure for reducing nystagmus, broadening the null position, and improving v

124 Idiopathic infantile periodic alternating nystagmus can be familial or occur in isolation; however

125 A1 mutations and episodic ataxia type 2 with nystagmus caused by CACNA1A mutations, the list of episo

126 erences between SCL and RGPL wearing for any nystagmus characteristics or compared with spectacle wea

127 quantitative data on retinal development and nystagmus characteristics.

128 Adults with congenital nystagmus (CN) show interaction areas that are 2x larger

129 t lens wearing does not significantly reduce nystagmus compared with baseline spectacle wearing.

130 Periodic alternating nystagmus consists of involuntary oscillations of the ey

131 The direction of optokinetic nystagmus correlates with visual perception in higher ma

132 A computer algorithm developed to detect nystagmus demonstrated a sensitivity of 99.1% (95% CI: 9

133 its small-amplitude, high-frequency pendular nystagmus despite positive ERG responses.

134 cond, miosis - clonidine and opioids; third, nystagmus - dextromethorphan.

135 s, and clinical characteristics of pediatric nystagmus diagnosed over a 30-year period.

136 The MVS-induced nystagmus diminished slowly but incompletely over multip

137 lations of the eyes with cyclical changes of nystagmus direction.

138 hildhood onset blindness, cerebellar ataxia, nystagmus, dorsal column dysfuction, and spasticity with

139 for increasingly better foveation; pendular nystagmus during each decile of the sensitive period was

140 measure for the progression and treatment of nystagmus during early childhood.

141 and of each child's time course of pendular nystagmus during the sensitive period.

142 diagnostic yield for patients with infantile nystagmus, enabling access to disease specific managemen

143 gest that vertigo with horizontal positional nystagmus, even in the absence of other initial neurolog

144 After consultation with 8 nystagmus experts, 37 items were administered to 206 peo

145 Nystagmus eye movement data from infants and young child

146 NOFF is a feasible method to quantify noisy nystagmus eye movement data.

147 affected by foveal hypoplasia with infantile nystagmus, following an autosomal recessive mode of inhe

148 The nystagmus foveation characteristics were similarly asses

149 Visuomotor comorbidities (eg, amblyopia, nystagmus, foveopathy, optic neuropathy) accounted for r

150 eatment, 4630 deg(2)) and a reduction of the nystagmus frequency compared with baseline at the 3-year

151 Furthermore, motor indices of nystagmus (frequency, amplitude, and intensity) were sig

152 Olmsted County, Minnesota, with any form of nystagmus from January 1, 1976, through December 31, 200

153 Physiologic gaze-evoked nystagmus (GEN) is one of many normal eye movements seen

154 nystagmus had a median onset at age 3 months and transit

155 ntrast, 2 patients with geotropic positional nystagmus had cerebellar peduncle and lateral medullary

156 RECENT FINDINGS: Some forms of nystagmus have relatively specific treatments, such as b

157 gaze deviation, direction-changing torsional nystagmus, horizontal ophthalmoplegia, and generalized s

158 Idiopathic congenital nystagmus (ICN) consists of involuntary and periodic ocu

159 n regarding the mechanisms causing infantile nystagmus, identification of new genes and determining t

160 Idiopathic infantile nystagmus (IIN) consists of involuntary oscillations of

161 Children with idiopathic infantile nystagmus (IIN) exhibit visual acuity deficits that have

162 Idiopathic infantile nystagmus (IIN) is a genetically heterogeneous disorder

163 Idiopathic infantile nystagmus (IIN) is a genetically heterogeneous disorder,

164 rtant cause of X-linked idiopathic infantile nystagmus (IIN).

165 y) versus memantine (40 mg/day) for acquired nystagmus in 10 patients (aged 28-61 years; 7 female; 3

166 nlarged corneal diameter in 32 eyes (48.5%), nystagmus in 15 children (23%), limbal stem cell deficie

167 (31.0%), manifest latent nystagmus or latent nystagmus in 17 (24.0%), and 2 (2.8%) each associated wi

168 ving OA and had minimal clinical signs (fine nystagmus in 2 patients and subtle iris transilluminatio

169 n 23 (32.4%), idiopathic or congenital motor nystagmus in 22 (31.0%), manifest latent nystagmus or la

170 strabismus in 13 (14%), cataract in 5 (6%), nystagmus in 3 (3%), and optic nerve dysplasia in 2 (2%)

171 e also briefly review aetiology of infantile nystagmus in afferent visual deficits caused by ocular d

172 ft velocity, frequency, and intensity of the nystagmus in each eye.

173 ce and clinical characteristics of childhood nystagmus in North America.

174 menace responses, with positional horizontal nystagmus in one dog.

175 ally with the standard dosage showed reduced nystagmus in only one eye.

176 The main types of nystagmus, in declining order, were nystagmus associated

177 eatment options for common forms of acquired nystagmus including vestibular and gaze holding dysfunct

178 isolated up-/downgaze palsy or up-/downbeat nystagmus, indicates that up- and downgaze pathways are

179 onent is taken into account representing the nystagmus-induced visual deprivation during the sensitiv

180 FRMD7 are causative of idiopathic infantile nystagmus influencing neuronal outgrowth and development

181 concept of four-muscle tenotomy surgery for nystagmus initially arose from objective eye movement re

182 Nystagmus intensity and foveation were poor indicators o

183 nts are significantly correlated to BCVA and nystagmus intensity in contrast to iris transilluminatio

184 retinal layer measurements at the fovea, (3) nystagmus intensity, (4) BCVA, (5) VEP asymmetry, (6) sk

185 hich reading is suboptimal), near logMAR VA, nystagmus intensity, and foveation characteristics (usin

186 the minimum angle of resolution (logMAR) VA, nystagmus intensity, and foveation characteristics as qu

187 uch as skin and hair pigmentation, BCVA, and nystagmus intensity, were significantly correlated to AS

188 Congenital nystagmus, involuntary oscillating small eye movements,

189 Nystagmus is a commonly encountered entity in clinical p

190 Nystagmus is a disorder of uncontrolled eye movement and

191 Infantile nystagmus is an involuntary, bilateral, conjugate, and r

192 Medical treatment of nystagmus is difficult, with often limited and variable

193 The rate of acuity development in infantile nystagmus is largely independent of the gaze-holding ins

194 syndrome (INS), formerly known as congenital nystagmus, is an ocular motor disorder in humans charact

195 or take the form of a tilt, even though the nystagmus itself is horizontal.

196 Amblyopia and nystagmus limited visual outcome, indicating the need fo

197 dizziness, false feelings of motion, nausea, nystagmus, magnetophosphenes, and electrogustatory effec

198 vision (strabismus, amblyopia, diplopia, and nystagmus) may have on musculoskeletal injury and fractu

199 ual acuity deficit and the prediction of the nystagmus model.

200 elated individuals presented with congenital nystagmus, motor delay, and deficient myelination on ser

201 ts had conjugate pendular (n = 4) or see-saw nystagmus (n = 2); gaze holding was stable in four patie

202 ft Foundation, National Eye Research Centre, Nystagmus Network UK.

203 l patients carrying LCA5 mutations presented nystagmus, night blindness, and progressive loss of visu

204 childhood, with a phenotype characterized by nystagmus, normal retinal examination, and mild disturba

205 aged 81 eyes from 42 patients with infantile nystagmus of mean age 19.8 months (range, 0.9-33.4 month

206 eton (21 patients) with periodic alternating nystagmus of which we describe clinical phenotype, genet

207 nd to exhibit long-lasting optokinetic after nystagmus (OKAN) as opposed to those that didn't.

208 o evaluate the efficacy of using optokinetic nystagmus (OKN) as an objective measurement of vision in

209 Look optokinetic nystagmus (OKN) consists of voluntary tracking of detail

210 fying experimental conditions of optokinetic nystagmus (OKN) result in different outcomes and may not

211 if an involuntary eye movement, optokinetic nystagmus (OKN), could serve as an objective measure of

212 elicit smooth pursuit, saccades, optokinetic nystagmus (OKN), vestibulo-ocular reflex (VOR), and verg

213 s and can be used to determine the impact of nystagmus on daily living in terms of both physical and

214 for up to thirty days, artificially inducing nystagmus on eight occasions.

215 nfidence interval [CI], 5.15-8.28) Infantile nystagmus, onset by 6 months, comprised 62 (87.3%) of th

216 The nystagmus optimal fixation function (NOFF) was defined a

217 Fixation stability was quantified using the nystagmus optimal fixation function (NOFF).

218 deled in terms of foveation characteristics (Nystagmus Optimal Fixation Function, NOFF) and of each c

219 tor nystagmus in 22 (31.0%), manifest latent nystagmus or latent nystagmus in 17 (24.0%), and 2 (2.8%

220 She had no nystagmus or vertigo at pneumatic otoscopy.

221 be performed (patients with poor fixation or nystagmus or young children).

222 g. idiopathic infantile periodic alternating nystagmus) or later in life.

223 ion is used for the treatment of strabismus, nystagmus, or other eye muscle disorders.

224 is (amblyopia, strabismus, optic neuropathy, nystagmus, or retinopathy of prematurity) by ICD-9 codes

225 en vascular loops and sensorineural hearing, nystagmus, or vertigo.

226 the long-term visual acuity, strabismus, and nystagmus outcomes in Group D retinoblastoma following m

227 improvement in sensory and motor indices of nystagmus (P > .1, Spearman correlation coefficient).

228 ltivariate logistic regression analysis were nystagmus (P < 0.001), longer delay in presentation (P <

229 tification of IIN and genetic counselling of nystagmus patients.

230 ntify SLC38A8 mutations from a cohort of 511 nystagmus patients.

231 first animal model for a form of congenital nystagmus, paving the way for development of therapeutic

232 is unclear whether the periodic alternating nystagmus phenotype is linked to NYS1, NYS5 (Xp11.4-p11.

233 Dizziness, nystagmus, phosphenes, and head ringing were related to

234 educed vision, poorly responsive pupils, and nystagmus presenting within the first year of life).

235 dysmyelination, sensorineural hearing loss, nystagmus, progressive cholestatic liver disease, pancre

236 nating disorder of the CNS, characterized by nystagmus, psychomotor delay, progressive spasticity and

237 ded ocular surgery for cataract, strabismus, nystagmus, ptosis, or nasolacrimal duct obstruction.

238 the items and identify items to propose new nystagmus QOL scales.

239 Applied to acquired nystagmus refractory to all other interventions, it is s

240 h longstanding, medication-resistant, upbeat nystagmus resulting from a paraneoplastic syndrome cause

241 dy fixation or small eye movements including nystagmus, results in small changes in measured refracti

242 s from 6 patients with ageotropic positional nystagmus revealed that the nodulus and vermis are commo

243 nate and concurrent validity between the new nystagmus scales and an existing vision-related QOL tool

244 nt head acceleration and induces a sustained nystagmus similar to natural vestibular lesions [5, 6].

245 We have developed a 29-item, nystagmus-specific QOL questionnaire (NYS-29) based on e

246 nd environmental" functioning as relating to nystagmus-specific QOL.

247 is associated with decreased visual acuity, nystagmus, strabismus, and photophobia, although pigment

248 anisms that could underlie various infantile nystagmus subtypes are also highlighted.

249 ical characterization of all these infantile nystagmus subtypes has been achieved recently through hi

250 Some forms of nystagmus suppress or change with convergence; co-contra

251 ystagmus, a subtype of fusion maldevelopment nystagmus syndrome (FMNS).

252 Infantile nystagmus syndrome (INS) can be idiopathic or associated

253 f life in children with idiopathic infantile nystagmus syndrome (INS) or INS associated with albinism

254 5 months-8 years) with idiopathic infantile nystagmus syndrome (INS) were used to develop a quantita

255 t of head position associated with infantile nystagmus syndrome (INS) when strabismus coexists, and f

256 Infantile nystagmus syndrome (INS), formerly known as congenital n

257 ead position (AHP) associated with infantile nystagmus syndrome (INS).

258 udy was conducted on patients with infantile nystagmus syndrome and myopia equal to or more than -1 d

259 PRK in patients with infantile nystagmus syndrome and myopia improved monocular and bin

260 Patients with idiopathic nystagmus syndrome often develop an abnormal head positi

261 head titling in patients who have idiopathic nystagmus syndrome.

262 dered a positive sign in the Horizontal Gaze Nystagmus Test (HGNT) used by United States police offic

263 rrected visual acuity, kinetic visual field, nystagmus testing, and pupillary light reflex.

264 the 6 domains of everyday living affected by nystagmus that were elicited by previous semistructured

265 onscious, reflex responses (e.g. optokinetic nystagmus) that don't require involvement of visual cort

266 ave been identified for idiopathic infantile nystagmus; three are autosomal (NYS2, NYS3 and NYS4) and

267 The effect of aging on torsional optokinetic nystagmus (tOKN) is unknown.

268 Additionally, other recent advances in nystagmus treatment, like the usage of 4-aminopyridine,

269 Eighty-one unrelated patients with nystagmus underwent routine ocular phenotyping using com

270 brought changes to many of the treatments of nystagmus variants.

271 .0% (OR 5.70, 95% CI: 4.01-8.12) and that of nystagmus was 3.3% (OR 90.34, 95% CI 24.73-330.02).

272 roll orientation on horizontal and vertical nystagmus was also measured and was found to affect only

273 Recently, a counterpart of gaze-evoked eye nystagmus was identified for head movements; in which th

274 However, nystagmus was more pronounced in the BS-Cat group (US-Ca

275 The amplitude of nystagmus was more strongly dependent on the direction o

276 Periodic alternating nystagmus was not detected clinically but only on eye mo

277 Nystagmus was not significantly different during SCL and

278 Nystagmus was pendular in 6 patients (4 oculopalatal tre

279 Periodic alternating nystagmus was predominantly associated with missense mut

280 Abnormal vertical optokinetic nystagmus was present in 19 (68%) of 28 subjects: 10 wit

281 he control group with unassociated infantile nystagmus was used to relate fixation stability to age-c

282 he 1- and 2-month examinations, no change in nystagmus waveform or NAFX was observed in any of the in

283 in terms of foveation characteristics of the nystagmus waveform.

284 Pendular nystagmus waveforms were also more frequent in the FRMD7

285 region, improved visual acuity, and improved nystagmus waveforms.

286 tons (70 patients) with idiopathic infantile nystagmus we identified 10 families and one singleton (2

287 Quick phases of nystagmus were also affected, but smooth pursuit, vergen

288 n (1 month to 4 years of age) with infantile nystagmus were assessed by using Teller acuity cards ori

289 Ophthalmology referrals, strabismus, and nystagmus were found to be statistically significantly h

290 rologic symptoms in the form of seizures and nystagmus were observed.

291 Variable degrees of nystagmus were present; three cases lacked nystagmus at

292 The frequency, amplitude, and intensity of nystagmus were significantly decreased after PRK (P < .0

293 g mechanisms underlying idiopathic infantile nystagmus, which has progressed through determining the

294 ur healthy human subjects developed a robust nystagmus while simply lying in the static magnetic fiel

295 The adult male subject had infantile onset nystagmus while the three other patients did not.

296 ntile nystagmus and by 1.7 to 2.5 octaves in nystagmus with associated sensory defect.

297 retinal GCs, most likely the ON-DCGCs, cause nystagmus with properties similar to those associated wi

298 og studied, this one showed a damping of the nystagmus within the first 4 weeks after treatment.

299 ) a low-amplitude ipsilesional right-beating nystagmus without fixation, (3) gaze-holding deficits, a

300 agnet oculomotor prosthesis, powered to damp nystagmus without interfering with the larger forces inv