ライフサイエンスコーパス: obese individual

1 among subpopulations of current smokers and obese individuals.

2 l muscle insulin signalling in sedentary and obese individuals.

3 oL and URTI incidence outcomes in overweight/obese individuals.

4 tween breakfast and health remain unclear in obese individuals.

5 cations in both normal weight and overweight/obese individuals.

6 ssociated with obesity but also found in non-obese individuals.

7 cle microvasculature has not been studied in obese individuals.

8 and SAT volume were significantly higher in obese individuals.

9 ctors largely affecting the CVD prognosis of obese individuals.

10 a cancer prevention method in overweight and obese individuals.

11 rgy-balance control and is often impaired in obese individuals.

12 nificant association with glaucoma status in obese individuals.

13 cose production was similar between lean and obese individuals.

14 cause of nonalcoholic fatty liver disease in obese individuals.

15 n an acute study in healthy, overweight, and obese individuals.

16 improved physical health status for severely obese individuals.

17 tification and early intervention of at-risk obese individuals.

18 reduced circulating levels of adiponectin in obese individuals.

19 als also supports risk factor control in non-obese individuals.

20 ive approaches to resolve type 2 diabetes in obese individuals.

21 ent populations of severe obese and diabetic obese individuals.

22 r restoration of B lymphopoiesis in aged and obese individuals.

23 s and obesity-related metabolic disorders in obese individuals.

24 mm in NW individuals and 0.79 and 0.68 mm in obese individuals.

25 Iron deficiency is common in overweight and obese individuals.

26 ular to reflect the situation in diabetic or obese individuals.

27 sociated with prevalent and incident DSPN in obese individuals.

28 success in preserving insulin sensitivity in obese individuals.

29 rbic acid can be effective in overweight and obese individuals.

30 sceral fat compared with subcutaneous fat in obese individuals.

31 in the development of insulin resistance in obese individuals.

32 ons was 9.1% in NW individuals and 6.08% for obese individuals.

33 n between homeostatic and reward networks in obese individuals.

34 D) risk among normal-weight, overweight, and obese individuals.

35 strong lipolytic activity, are decreased in obese individuals.

36 mulae are inaccurate, especially in severely obese individuals.

37 Such activation may be disordered in obese individuals.

38 of type 2 diabetes in a large population of obese individuals.

39 t individuals, compared to 4.22% to 7.99% in obese individuals.

40 y larger than those in metabolically healthy obese individuals.

41 ss and blood pressure reduction in centrally obese individuals.

42 d processing unique to specific subgroups of obese individuals.

43 is significantly augmented in overweight and obese individuals.

44 identified the metabolic syndrome in equally obese individuals.

45 was evaluated in arteries from nonobese and obese individuals.

46 d in patients of normal weight compared with obese individuals.

47 tabolism of essential fatty acids focused on obese individuals.

48 in treatment of metabolic syndrome in mildly obese individuals.

49 ze and daily energy intake in overweight and obese individuals.

50 ptin was expected to decrease body weight in obese individuals.

51 measures of atherosclerosis is diminished in obese individuals.

52 P-2) after gastric sleeve surgery in healthy obese individuals.

53 tify plasma Hsp60 concentrations in lean and obese individuals.

54 ne, a common air pollutant, are augmented in obese individuals.

55 and insulin-resistant normal-weight (NW) or obese individuals.

56 nd 5.6%, 8.3%, and 8.3%, respectively, in IS-obese individuals.

57 measures were greater for normal weight than obese individuals.

58 e 2 diabetes mellitus is heterogeneous among obese individuals.

59 his effect was not observed in overweight or obese individuals.

60 lly relevant to plasma lipids, especially in obese individuals.

61 elated to impaired FAO in HSkMC derived from obese individuals.

62 ble weight loss and metabolic improvement in obese individuals.

63 piration rates were similar between lean and obese individuals.

64 proinflammatory cytokines in adipocytes from obese individuals.

65 for predicting weight loss in overweight and obese individuals.

66 a diverse repertoire in SAT of overweight or obese individuals.

67 ol is able to improve glucose homeostasis in obese individuals.

68 the gut, characterize other vital organs in obese individuals.

69 increased risk of liver tumor development in obese individuals.

70 ences of cardiovascular events and cancer in obese individuals.

71 ributing to the promotion of colon cancer in obese individuals.

72 rdiovascular risks for metabolically healthy obese individuals.

73 entrations of saturated fatty acids found in obese individuals.

74 se (NAFLD) is a common metabolic disorder in obese individuals.

75 ased risk of psoriasis in both obese and non-obese individuals.

76 stronger effect observed in nonobese than in obese individuals.

77 the clinical situation of kidney donation by obese individuals.

78 ity and reduces the incidence of diabetes in obese individuals.

79 trition, the latter exclusively in non-super obese individuals.

80 of OPN mRNA was higher in adipose tissue of obese individuals (0.13 +/- 0.04 vs. 0.04 +/- 0.01, P <

81 g/kg liposomal amphotericin B in 16 morbidly obese individuals (104-177 kg).

82 ant and normal weight (IR-NW), and 72 of 330 obese individuals (22%) were classified as insulin sensi

83 Fifty-two overweight and slightly obese individuals (30 men and 22 postmenopausal women, m

84 In obese individuals, 6 weeks of extended morning fasting i

85 greater mean clinical attachment loss among obese individuals, a higher mean body mass index (BMI) a

86 s that may confer susceptibility to NAFLD in obese individuals across multiple ethnic groups.

87 bly, ANAs were less common in overweight and obese individuals (age-adjusted POR 0.74) than in person

88 the associations among metabolically healthy obese individuals and 4 different presentations of incid

89 pression is increased in adipose tissue from obese individuals and animals.

90 ipose tissue (BAT) is lower in overweight or obese individuals and in diabetes.

91 We examined FGF21 serum levels in lean and obese individuals and in response to dietary manipulatio

92 thway-based association studies in extremely obese individuals and normal-weight controls.

93 SMPD3 was elevated in PBMCs from obese individuals and positively corelated with TNF-alph

94 erlying increased breast cancer mortality in obese individuals and provide a novel preclinical ration

95 iatric surgery (MBS) leads to weight loss in obese individuals and reduces comorbidities such as type

96 vascular comorbidities are more prevalent in obese individuals and remain the basis for pretransplant

97 menting commensal, was markedly decreased in obese individuals and was inversely correlated with seru

98 ed by altering the nutrient load in lean and obese individuals and whether their microbiota are corre

99 s (NASH), 27 patients with NAFLD, 15 healthy obese individuals, and 39 healthy nonobese individuals (

100 omorbidity affecting white adipose tissue in obese individuals, and corrected impaired brown adipocyt

101 GE also occurs faster in obese individuals, and is associated with increased bloo

102 valent in human populations, particularly in obese individuals, and is characterized by progressive p

103 velopment, particularly among overweight and obese individuals, and offer a method for risk assessmen

104 nfluence daily energy balance, is reduced in obese individuals, and predicts future weight gain in th

105 art disease, CVD, and all-cause mortality in obese individuals appeared largely limited to men, and t

106 homeostatic appetite markers seen in reduced-obese individuals are a compensatory mechanism that driv

107 Obese individuals are at greater risk for hospitalizatio

108 Obese individuals are considered a high-risk group for d

109 However, not all obese individuals are insulin resistant, which confounds

110 Morbidly obese individuals are predisposed to a wide range of dis

111 ulin-stimulated SCAT glucose uptake rates in obese individuals are proportional to whole-body fat mas

112 Obese individuals are susceptible to comorbidities, incl

113 Formerly obese individuals are susceptible to metabolic disorders

114 A greater number of morbidly obese individuals are undergoing bariatric surgery, expa

115 sity rates may affect the decision to accept obese individuals as donors.

116 In the overweight and obese individual, as well as in persons with hypertensio

117 their metabolites, and PCP were measured in obese individuals at the initial moment of their enrolli

118 erivascular fat were harvested from severely obese individuals before (n = 20) and 6 months after bar

119 We monitored skeletal muscle metabolism in obese individuals before and over 52 weeks after metabol

120 PVAT anticontractile function in tissue from obese individuals before surgery.

121 Sarcopenic obesity was defined as obese individuals (BMI >/=30) in the lowest tertile of s

122 mily history of diabetes, similar to that in obese individuals (BMI >= 30 kg/m2) with a family histor

123 ascular benefit achieved with weight loss in obese individuals, but mechanisms are currently unknown.

124 action in tissue from both lean and severely obese individuals, but responses to EPS were blunted wit

125 ncreatic ductal adenocarcinoma (PDAC) and in obese individuals, but whether it contributes to PDAC de

126 Among obese individuals, C-allele homozygotes at rs8192675 had

127 In obese individuals, calorie restriction increased AT APOM

128 Overweight and obese individuals carrying the AMY1-AMY2 rs11185098 geno

129 n binge eating phenotypes as the subgroup of obese individuals characterized by disordered eating.

130 t-term overfeeding in BMI-matched overweight/obese individuals classified as IS or insulin resistant

131 with low-grade inflammation of the tissue in obese individuals, contributes to the development of ins

132 In obese individuals, deregulation of a specific adipokine,

133 With immunohistochemistry, we categorized obese individuals dichotomously as having inflamed fat (

134 Inflamed CLS+ obese individuals displayed higher plasma insulin, homeo

135 ean BMI and the percentage of overweight and obese individuals do not fully describe population chang

136 Around 25% of obese individuals do not show excess liver fat, whilst 1

137 A subset of obese individuals does not exhibit metabolically unfavor

138 treatment with PGE(2), which is increased in obese individuals, down-regulated SIRT1 levels, leading

139 SAT and VAT biopsies were obtained from obese individuals during gastric bypass surgeries [ n =

140 reflect variable toxicokinetics in lean and obese individuals during times of increasing and decreas

141 All-cause 10-year mortality in obese individuals eligible for bariatric surgery can be

142 These data reveal that myotubes of severely obese individuals enhance insulin action and stimulate e

143 The prevalence of polyneuropathy is high in obese individuals, even those with normoglycemia.

144 Leukocytes from obese individuals exhibit an impaired SPM signature.

145 Obese individuals exhibit an increase in pancreatic beta

146 Moreover, leukocytes from obese individuals exhibited decreased 5-LOX levels and r

147 n subcutaneous adipose tissues isolated from obese individuals exhibited reduced expression of APCDD1

148 samples by using pyrosequencing in morbidly obese individuals, explored before (0 mo), 3 mo after, a

149 on anthropometrics and glycemic outcomes in obese individuals following a 2-phase dietary weight los

150 h successful replication in 1,584 overweight/obese individuals from a community-based cohort study) a

151 st, AMY1 CNs were accurately measured in 761 obese individuals from the DiOGenes study.

152 e profile in a sample of healthy, mostly non-obese individuals from the general population and only f

153 In obese mice and obese individuals, Gpnmb expression was induced in ATMs.

154 Compared with normal BMI, obese individuals had a higher risk of coronary heart di

155 Metabolically healthy obese individuals had a higher risk of coronary heart di

156 erentiated, postmitotic myofiber nuclei from obese individuals had elevated gammaH2AX abundance compa

157 Moderately fit obese individuals had significantly lower visceral fat l

158 mmunofluorescence microscopy, we report that obese individuals have compromised intestinal BCRP funct

159 First, it was confirmed that obese individuals have higher cerebral 5-HT2A receptor b

160 pokine involved in metabolic regulation, and obese individuals have higher concentrations.

161 pulmonary disease (COPD), whereby overweight/obese individuals have improved survival, has been well-

162 The reason why obese individuals have low circulating SHBG has been att

163 We tested the hypothesis that obese individuals have lower core temperatures than thos

164 Regular exercise can also improve S(I) in obese individuals; however, it is unknown whether exerci

165 rozygous variants in SRC-1 found in severely obese individuals impair leptin-mediated Pomc reporter a

166 2D risk among normal-weight, overweight, and obese individuals in up to 8,124 incident T2D cases.

167 iated microbial and metabolic alterations in obese individuals, including the decreased abundance of

168 rt failure in normal weight, overweight, and obese individuals increased with increasing number of me

169 93590 [A/C] and rs1378577 [T/G]) in morbidly obese individuals indicated that elevated ABCG1 expressi

170 In obese individuals, IRF5 expression is negatively associa

171 ic strategies for correcting such defects in obese individuals is challenging.

172 ce of the results for cancer in diabetic and obese individuals is that the initial stages of the proc

173 ependent of comorbidities commonly affecting obese individuals, is not clear.

174 cardiovascular risk factors are enriched in obese individuals, it has not been easy to dissect the e

175 fitness is protective against incident AF in obese individuals, its effect on AF recurrence or the be

176 Obese individuals lose approximately 6 to 8 kg (approxim

177 Mitochondria from obese individuals maintained higher (more negative) extr

178 standing the metabolic changes that occur in obese individuals may also help to elucidate more effect

179 lation of ENaC by metabolic abnormalities in obese individuals may be a likely cause of the hypertens

180 res of FGF2 or inhibit FGFR-1 in abdominally obese individuals may be important cancer prevention str

181 th body fat levels, adiponectin reduction in obese individuals may play a causal role in the symptoms

182 ch are generally disturbed in overweight and obese individuals, may improve by increased dairy intake

183 However, a proportion of obese individuals might not be at an increased risk for

184 in subjects with normal glucose tolerance in obese individuals (n = 54) and a population-based sample

185 e associated to cardiovascular phenotypes in obese individuals, namely atherosclerosis and liver fat

186 natriuretic peptide (BNP) concentrations in obese individuals ("natriuretic handicap") may play a ro

187 In obese individuals, no differential (FAST versus BFAST) e

188 by reducing levels of these risk factors in obese individuals not able to achieve sustained weight l

189 -related increase in mortality than severely obese individuals not undergoing surgery (P = .001).

190 d increase in mortality observed in severely obese individuals not undergoing surgery.

191 disorder (BED) were compared with 19 non-BED obese individuals (OB) and 19 lean control subjects (LC)

192 ing the concept of a natriuretic handicap in obese individuals observed in non-Hispanic whites to thi

193 In obese individuals, oleoylethanolamide showed a trend tow

194 in NASH patients but not in fatty livers in obese individuals or in high-fat diet (HFD)-fed mice.

195 ing starvation, and is abnormally induced in obese individuals or those with diabetes.

196 of mice and cultured with serum from lean or obese individuals or with neutrophils from L2-IL1B mice.

197 functions, satiation, satiety, and weight in obese individuals over 16 weeks.

198 ar risk factors may also be decreasing among obese individuals over time.

199 th increasing BMI and were nonsignificant in obese individuals (p < 0.05 in nonobese, p > 0.1 in obes

200 ificant variability exists between similarly obese individuals, pointing to qualitative characteristi

201 In obese individuals, primary event rates were similar with

202 l adipocytes, and from healthy and unhealthy obese individuals, promoted comparable inflammatory resp

203 r data show that diet-induced weight loss in obese individuals reduces colorectal inflammation and gr

204 nce to COVID-19 prevention strategies in all obese individuals regardless of age.

205 Metabolically healthy obese individuals (relative risk [RR], 1.24; 95% CI, 1.0

206 ontributing to greater infection severity in obese individuals remain unclear.

207 may affect health parameters in a cohort of obese individuals reporting sleeping less than 6.5 hours

208 A morbidly obese individual's increased cardiac output requires adm

209 Nineteen obese individuals seeking treatment for binge eating dis

210 for new alternatives to treat obesity since obese individuals seem to have less brown adipose tissue

211 Sites with periodontitis in obese individuals showed higher levels of IL-6 and TNF-a

212 tence of healthy obese phenotypes because IS-obese individuals showed increased cardiometabolic risk.

213 From 2000 to 2014, the proportion of obese individuals significantly increased 44.9% and the

214 NP627 treatment of adipocytes from obese individuals significantly inhibited PKCdeltaI cata

215 ns was analyzed in overnight-fasted lean and obese individuals subjected to a whole-mouth stimulation

216 In non-obese individuals, subjects with high triglycerides, hig

217 tive memory CD8 T cell responses and renders obese individuals susceptible to infection remains unkno

218 studies have found a lower risk of dying for obese individuals than for normal-weight individuals.

219 Compared to all non-obese individuals, the OR for depressive symptoms was hi

220 em and food-related behavior in binge-eating obese individuals, these results support a dissociation

221 her luminal enhancers of iron absorption) in obese individuals to improve iron status may have a limi

222 lity of these traits to predict responses of obese individuals to pharmacotherapy.

223 s of NAFLD progression (ranging from healthy obese individuals to those with steatosis), as well as r

224 not known if opioid use for chronic pain in obese individuals undergoing bariatric surgery is reduce

225 receptors (PLXNA1-4; NRP1-2) in 573 severely obese individuals; variants disrupted secretion and/or s

226 The relative odds of impairment for obese individuals versus normal-weight individuals signi

227 In obese individuals, visceral adipose tissue (VAT) is the

228 ociation of S/P with the metabolic status of obese individuals was further validated in a cross-secti

229 metabolism of nutrients in healthy lean and obese individuals, we investigated whether ingestion of

230 Overweight and obese individuals were assigned to the omega-3 arm (n =

231 mic H1N1 influenza A virus (pH1N1) outbreak, obese individuals were at greater risk for morbidity and

232 Overweight and class I to III obese individuals were at higher risk for mechanical ven

233 Fourteen obese individuals were re-examined after RYGB surgery.

234 Obese individuals were stratified into an obesity surger

235 Serum samples from obese individuals were taken before patients lost weight

236 e dataset, sampled from lean, overweight and obese individuals, were analysed to demonstrate parallel

237 ssue and systemic insulin resistance (IR) in obese individuals, which is represented by ADIPO-IR and

238 r percentage contribution to the sum PCBs in obese individuals, while higher chlorinated PCBs had a h

239 Our findings have primary relevance to obese individuals who are at an increased risk of develo

240 tric surgery have longer survival times than obese individuals who did not have bariatric surgery, bu

241 he general population and are longer than of obese individuals who did not receive surgery.

242 ass surgery and 7925 group-matched, severely obese individuals who did not undergo surgery were ident

243 y contributed to a decline in IQ, even among obese individuals who displayed evidence of the metaboli

244 rrant further investigation, particularly in obese individuals who have a reduced reliance on muscle

245 Thus, obese individuals who have low fruit and vegetable consu

246 cused on a unique subgroup of overweight and obese individuals who have normal metabolic features des

247 hanges in adiposity among 692 overweight and obese individuals who were randomly assigned to diets va

248 e successful use of lorcaserin in a morbidly obese individual with decompensated cirrhosis evaluated

249 We analyzed whether obese individuals with a "thrifty" phenotype, that is, g

250 s (miR-18a, miR-30e) were up-regulated among obese individuals with a healthy periodontium.

251 g to a 2 x 2 factorial design, 86 overweight/obese individuals with a large waist circumference and a

252 benefits of hesperidin 2S in overweight and obese individuals with a relatively healthy endothelium.

253 and weight fluctuation on rhythm control in obese individuals with AF.

254 ory fitness improvement on rhythm control in obese individuals with AF.

255 lactulose:mannitol (Lac:Man) permeability in obese individuals with and without liver steatosis under

256 unction in obesity, and specifically compare obese individuals with and without metabolic syndrome (M

257 This mechanism may operate in obese individuals with chronic inflammation, thus making

258 lic effects of GCKR inhibition in overweight/obese individuals with diabetes mellitus.

259 style behavior intervention in overweight or obese individuals with diabetes mellitus.

260 tention to prevention of vascular disease in obese individuals with diabetes.

261 al training (HIT) (Home-HIT) intervention in obese individuals with elevated cardiovascular disease (

262 12 weeks of virtually supervised Home-HIT in obese individuals with elevated cardiovascular disease r

263 wnregulated in the omental adipose tissue of obese individuals with extreme insulin sensitivity and,

264 Using the same reference, obese individuals with high mMED did not experience sign

265 s) the findings were broadly similar, though obese individuals with high mMED retained a modestly inc

266 gnetic resonance imaging in 39 overweight or obese individuals with impaired fasting glucose, impaire

267 lel study was conducted in 50 overweight and obese individuals with increased waist circumference and

268 laboratory- and gym-based HIT protocols for obese individuals with low fitness and mobility has been

269 human adipose-derived stem cells (ASCs) from obese individuals with MNCs and analyzed their reciproca

270 u-opioid receptor antagonist, GSK1521498, in obese individuals with moderate binge eating.

271 and hepatic mRNA expression were measured in obese individuals with NAFLD or NASH.

272 During a mean follow-up of 5.4 years, obese individuals with no metabolic abnormalities had a

273 escents (age range: 12-16 yr) underwent MRI: obese individuals with OSAS (n = 49), obese control subj

274 (miR-30e, miR-106b) were up-regulated in non-obese individuals with periodontal disease.

275 d local immune and inflammatory responses in obese individuals with periodontitis may explain the agg

276 ue biopsies collected from normal weight and obese individuals with periodontitis; miRNA expression p

277 Obese individuals with persistent low-grade systemic inf

278 is a randomized crossover study involving 12 obese individuals with prediabetes.

279 rpose of this study was to determine whether obese individuals with reduced adipose tissue inflammati

280 Heterogeneity exists among obese individuals with respect to the neural correlates

281 Among 4,021 obese individuals with sinus rhythm and no history of at

282 ry fitness predicts arrhythmia recurrence in obese individuals with symptomatic AF.

283 (n = 633), obese non-diabetic (n = 494), and obese individuals with T2D (n = 153) from German populat

284 scular composite end points among overweight/obese individuals with T2D and whether a lifestyle inter

285 ncluded in this report were 3,845 overweight/obese individuals with T2D who provided consent for gene

286 These hormones are both often elevated in obese individuals with therapy-resistant hypertension.

287 mptoms was higher in metabolically unhealthy obese individuals with two or more metabolic risk factor

288 pecies (DCAS) was significantly increased in obese individuals with type 2 diabetes (T2DM) from a cas

289 riction and exercise-mediated weight loss in obese individuals with type 2 diabetes is associated wit

290 itus support and education arm in overweight/obese individuals with type 2 diabetes mellitus with tri

291 tent of food consumption among overweight or obese individuals with type 2 diabetes.

292 Overweight/obese individuals without apnea have a moderately compro

293 -based analysis demonstrated that overweight/obese individuals without apnea rely on both more favora

294 Obese individuals without cardiac disease with (OB/MS+,

295 ethnicity, and sex-matched normal-weight and obese individuals without diabetes mellitus.

296 etic subjects compared with those in equally obese individuals without metabolic syndrome.

297 efined, and metabolically healthy overweight/obese individuals (without hyperinsulinaemia) have been

298 hich results in an ever-increasing number of obese individuals worldwide.

299 seen a rapid expansion of the proportion of obese individuals worldwide.

300 stematically evaluated within overweight and obese individuals, yet its use within pregnancy has not