ライフサイエンスコーパス: obstructed kidney

1 ntiapoptotic and antifibrotic effects in the obstructed kidney.

2 1a1, FnEDA, and TIMP1 mRNA expression in the obstructed kidney.

3 filtration of T cells and macrophages in the obstructed kidney.

4 ndogenous beta-galactosidase activity in the obstructed kidney.

5 ced significant upregulation of FnEDA in the obstructed kidney.

6 is greater in the adult than in the neonatal obstructed kidney.

7 and progressive interstitial fibrosis of the obstructed kidney.

8 the fibrotic response observed in innervated obstructed kidneys.

9 r-1(+) inflammatory DCs were also present in obstructed kidneys.

10 enal fibrogenesis evident in vehicle-treated obstructed kidneys.

11 ha and vascular endothelial growth factor in obstructed kidneys.

12 bone marrow-derived fibroblast precursors in obstructed kidneys.

13 downregulation of both laminin and TINag in obstructed kidneys.

14 ta expression or Smad 2/3 phosphorylation in obstructed kidneys.

15 tion and nuclear translocation of smad2/3 in obstructed kidneys.

16 differentiated from obstructed and partially obstructed kidneys.

17 obstructed CSF-1-deficient compared with WT obstructed kidneys.

18 erved renal mass and gross morphology of the obstructed kidneys.

19 pletely abolished alpha SMA induction in the obstructed kidneys.

20 prevented renal interstitial fibrosis in the obstructed kidneys.

21 TIMP-1 production in HK-2 cells and ureteral obstructed kidneys.

22 ulointerstitial fibrosis was observed in the obstructed kidneys.

23 with the expert panel in 92% (12/13) of the obstructed kidneys, 93% (38/41) of the unobstructed kidn

24 A levels remained relatively constant in the obstructed kidney after ureteral ligation.

25 b accumulated at lower concentrations in the obstructed kidney and exhibited a more diffuse whole-bod

26 s urothelial remodelling that stabilizes the obstructed kidney and limits renal injury.

27 and alpha-smooth muscle actin expression in obstructed kidneys and enhanced tubulointerstitial injur

28 3 expression increased in the fibroblasts of obstructed kidneys and was associated with increased Ca(

29 al cells upregulated the chemokine CXCL16 in obstructed kidneys, and circulating fibroblast precursor

30 of nonobstructed kidneys, in 92% (33/36) of obstructed kidneys, and in 45% (13/29) of equivocal kidn

31 rt panel to have 41 unobstructed kidneys, 13 obstructed kidneys,and 9 equivocal findings.

32 ted compared to mice with intact MG53 in the obstructed kidney compared to the contralateral unobstru

33 nsin-(1-7) to mice with UUO caused injury in obstructed kidneys compared with controls and increased

34 e-dependent degradation of SnoN was found in obstructed kidney, compared with sham controls.

35 In the dilated tubules of obstructed kidney, ERK/YAP1/Klf5/cyclin D1 axis was up-r

36 ed the beneficial effect of enalapril in the obstructed kidney for all parameters.

37 Obstructed kidneys from beta6(-/-) mice showed less inju

38 increased apoptosis and macrophage influx in obstructed kidneys from Mas(-/-) mice, compared with unt

39 The ureteral obstructed kidneys from MG53 deficient mice also showed

40 ignificantly more inflammation than ureteral obstructed kidneys from MG53 intact mice.

41 In obstructed kidneys from mice with gene deletion of Mas (

42 Obstructed kidneys from p53-/- mice did not express p53

43 Compared with WT controls, obstructed kidneys from TKO mice at day 14 had increased

44 from beta6(-/-) mice showed less injury than obstructed kidneys from wild-type (WT) mice, associated

45 hospho-FAK-positive CD11b macrophages in the obstructed kidneys from WT mice was clearly attenuated i

46 Obstructed kidneys in p53+/+, p53+/-, and p53-/- mice di

47 Obstructed kidneys in p53+/+, p53+/-, and p53-/- mice we

48 Obstructed kidneys in p53+/- and p53-/- mice exhibited e

49 Obstructed kidneys in p53-/- and p53+/- mice showed virt

50 These data suggest that apoptosis in obstructed kidneys involves p53-dependent as well as p53

51 hat downregulation of SnoN expression in the obstructed kidney is mediated by an enhanced ubiquitin-d

52 For obstructed kidneys (n = 34), renal pelvic urine attenuat

53 In the obstructed kidney of the BM-chimeric female mice, a mean

54 In contrast, the obstructed kidneys of adiponectin-knockout mice had fewe

55 hi and T cells and less apoptotic TEC in the obstructed kidneys of Csf1(op)/Csf1(op) mice compared wi

56 The obstructed kidneys of HO-1(-/-) mice also had greater ma

57 Macrophages isolated from obstructed kidneys of mice lacking AT1 receptors solely

58 ) collagen - was substantially higher in the obstructed kidneys of mice with Agtr1(-/-) marrow than i

59 teinase-9 (MMP-9) induction was found in the obstructed kidneys of tPA(-/-) mice, which led to a dram

60 In obstructed kidneys, PAK2 and c-abl activity were increas

61 in the neonatal rat delays maturation of the obstructed kidney, possibly in part through suppressed e

62 dies: the unobstructed kidney; the partially obstructed kidney, proximally or distally obstructed, wi

63 cantly higher levels of each molecule in the obstructed kidney than in the nonobstructed kidney, the

64 expression and synthesis of periostin in the obstructed kidney that associated with the progression o

65 ation and extracellular matrix remodeling in obstructed kidneys, thus ameliorating tubulointerstitial

66 In mouse obstructed kidney, tPA, LRP-1, and MMP-9 were concomitan

67 Increased collagen I mRNA in the obstructed kidney was detected by in situ hybridization.

68 Activated Smad 2 levels in beta6(-/-) obstructed kidneys were lower than in WT UUO mice, and d

69 wth factors, UUO stimulates apoptosis in the obstructed kidney, which is quantitatively greater in th

70 analysis suggested resident DC maturation in obstructed kidneys with increased CD11b and less F4/80 e

71 tion and impairment of function; the totally obstructed kidney, with arrested renal function; and the

72 ce developed more severe renal damage in the obstructed kidney, with marked tubular atrophy and inter