ライフサイエンスコーパス: occlude

1 questered and the PX lipid-binding sites are occluded.

2 ected localization accuracy when one ear was occluded.

3 conventional venography, 73 were stenotic or occluded.

4 y thromboembolism model, larger vessels were occluded.

5 le to their partner whose view was partially occluded.

6 wnstream of mGlu5 activation is mimicked and occluded.

7 ure that positions LAIR1, while itself being occluded.

8 and 80 (64%) posterior tibial arteries were occluded.

9 h conditions even if the object is partially occluded.

10 target sites, which otherwise are sterically occluded.

11 ng conformation, with the extracellular gate occluded.

12 occupy various sites in Otop1 and Otop3 and occlude a central tunnel.

13 onserved motifs; curiously, this arrangement occludes a region usually involved in ANK-mediated prote

14 stributed pools of lithogenic, free organic, occluded, adsorbed, and precipitated phosphorus (P) form

15 nflammation, while the nature of the primary occluding agents has remained elusive.

16 interpret this as evidence that supercoiling occludes AGT binding sites.

17 tructure in a novel conformation, apo inward-occluded and a new nucleotide-bound state, high-energy o

18 nd maltose interaction sites, whereas inward-occluded and inward conformations present only a single

19 ibogaine complexes captured in outward-open, occluded and inward-open conformations.

20 structure reported here spontaneously adopt occluded and inward-open conformations.

21 ptured in inward-closed, inward-open, inward-occluded and outward-facing conformations.

22 mechanisms of the biomineral [7] and remain occluded and preserved in the skeleton [8-10].

23 l index <0.7 is more sensitive in diagnosing occluded and significantly stenotic tibial artery diseas

24 SF region displayed conductive, constricted, occluded, and dilated states, in qualitative agreement w

25 so-called outward, outward-occluded, inward-occluded, and inward GLUT1 conformations.

26 s been crystallized in outward-open, outward-occluded, and inward-open states.

27 In summary, PEAK1's kinase cleft is occluded, and its newly identified SHED region may promo

28 a relatively lower resting Ca(2+) level that occluded any further drop in Ca(2+) in response to theta

29 okinase and Tissue Plasminogen Activator for Occluded Arteries [GUSTO] classification moderate or sev

30 ), GUSTO (Global Usage of Strategies to Open Occluded Arteries), and BARC (Bleeding Academic Research

31 50 nm, where PUT selectively shrank veins or occluded arteries.

32 BVSs are transient implants that support the occluded artery for 6 mo and are completely resorbed in

33 Recanalization of the occluded artery through thrombolysis and/or endovascular

34 retinal ischemia resolved, we found that the occluded artery was the cilioretinal artery and not the

35 The embedding shell and the occluded Asp act as an integral until which minimally re

36 from the extracellular half before becoming occluded at a central constriction point consisting of t

37 irectly contact pObs only where an otherwise occluding basement membrane remains incompletely assembl

38 TPase ion pumps translocate their substrates occluded between helices in the center of the transmembr

39 results in favorable binding to GluN2A, but occludes binding to GluN2B.

40 tion of magnetic nanoparticles to reversibly occlude blood flow in microvessels.

41 n of plaques within the artery wall that can occlude blood flow to the heart and cause myocardial inf

42 This occludes blood flow, leads to inflammation, and increase

43 asculature in the rat cremaster, effectively occluding blood flow.

44 he EnvC LytM domain that is here found to be occluded by a "restraining arm" suggesting a self-inhibi

45 hibitory neurotransmission were mimicked and occluded by an antagonist of GPR55, suggesting that ther

46 an epicardial coronary artery is narrowed or occluded by an intramural hematoma.

47 The lumen of the CdiB pore is occluded by an N-terminal alpha-helix and the conserved

48 the differences between splice variants are occluded by antiepileptic drugs that bind to and stabili

49 also have inaccessible ATP-binding pockets, occluded by aromatic residues that mimic a cofactor-boun

50 ol (2-AG) synthesis, and it was mimicked and occluded by CB1 receptor agonists, indicating it was med

51 Prominent GV and EV were occluded by EIS.

52 (LTP), expressed mostly postsynaptically and occluded by inhibitory avoidance training.

53 ctivation of group II mGlu receptors was not occluded by LTP induced with high-frequency trains of st

54 ating the exposure of residues that would be occluded by MPER trimerization.

55 highly correlated with the volumes that are occluded by quadromers (four residues) in the primary st

56 ent decrease in paired pulse ratios, and was occluded by raising glutamate release probability.

57 ost cross-conserved protein determinants are occluded by self-N-glycan shielding, limiting B cell rec

58 rate binding to the high-energy state is not occluded by steric hindrance.

59 is located in the head domain and is partly occluded by the bound Fab in the crystal structure.

60 ons in which effector-binding interfaces are occluded by the cell membrane.

61 ine Fe and Al oxides by 1 M HCl, releasing P occluded by these oxides into solution.

62 erefore developed a novel method to randomly occlude capillaries in the rat hindlimb to mimic the cap

63 performed in 60 patients (30 per group with occluded [cases] and patent [control subjects] grafts) o

64 an autoinhibitory conformation, with a self-occluded catalytic site and a fully-closed cofactor pock

65 We employed radioactive isotopes to quantify occluded cations under steady-state conditions.

66 t we observed a large, hydrophilic and fully occluded cavity at the level of the cytoplasmic membrane

67 ell responses in macaques vaccinated with an occluded CD4 binding site on the HIV envelope antigen, d

68 er subunit contains a unique hydrophobic but occluded central pore, but it is unclear whether the bas

69 melting of glacial ice and direct release of occluded CO(2) gases into the water column.

70 lysaccharides, heparan sulfate mimetics, and occluding compounds.

71 ysis of mCST's unique lumen-facing partially-occluded conformation, coupled with the characterization

72 Compared to the outward-facing occluded conformation, our structure reveals a major til

73 suggest that pre-hydrolytic P-gp occupies an occluded conformation.

74 the pre-hydrolytic state, consistent with an occluded conformation.

75 nversely, JJC8-091 steers DAT towards a more occluded conformation.

76 T, in a Na(+)/substrate-bound, inward-facing occluded conformation.

77 analysis suggested that outward and outward-occluded conformations present multiple beta-d-glucose a

78 open conformation but instead favor two more occluded conformations.

79 main spectroscopy to computationally extract occluding content from layers whose thicknesses are wave

80 okinase and Tissue Plasminogen Activator for Occluded Coronary Arteries (GUSTO) scale.

81 ing scales (Global Use of Strategies to Open Occluded Coronary Arteries [GUSTO], Thrombolysis in Myoc

82 Global Use of Strategies to Open Occluded Coronary Arteries severe/moderate bleeding rate

83 ated GUSTO (Global Use of Strategies to Open Occluded Coronary Arteries) moderate, severe, or life-th

84 r of GUSTO (Global Use of Strategies to Open Occluded Coronary Arteries) moderate/severe bleeding (1.

85 e of GUSTO (Global Use of Strategies to Open Occluded Coronary Arteries) severe bleeding was 0.3% in

86 ated GUSTO (Global Use of Strategies to Open Occluded Coronary Arteries) severe/life-threatening/mode

87 immediate pharmacological reperfusion of the occluded coronary artery and long-term aspirin to preven

88 TO-PCI was defined as intervention of a 100% occluded coronary artery presumed to be >=3 months old.

89 proven efficacy is early reperfusion of the occluded coronary artery.

90 early coronary angiography having an acutely occluded culprit coronary artery.

91 Conversely, carnivorous reptiles have non-occluding dentitions that engender negligible bone damag

92 MRN gains access to occluded DNA ends by removing Ku or other DNA adducts vi

93 ximately 15% of saphenous vein grafts (SVGs) occlude during the first year after coronary artery bypa

94 reviously unidentified electron transfer was occluded during previous in vivo studies due to the earl

95 y cerebellin-1 and neuroligin-3 functionally occlude each other during development of calyx synapses.

96 the selective antagonist XE991 mimicked and occluded efferent-mediated slow excitation in CD afferen

97 ne family targeted a previously subdominant, occluded epitope at the head interface.

98 antigen results in GC B cells targeting the occluded epitope, and induces a class of protective anti

99 e insights into vaccine strategies using the occluded epitope.

100 nv conformation resulting in the exposure of occluded epitopes recognized by CD4-induced antibodies.

101 These antibodies mostly recognize occluded epitopes that can be exposed upon binding of CD

102 ement by antibodies that recognize otherwise occluded epitopes.

103 ual cortex rapidly lose responsiveness to an occluded eye and come to respond better to the open eye.

104 n the distal stump of one of the bilaterally occluded femoral arteries and the accompanying vein.

105 .9; P=0.047) in participants with completely occluded femoral arteries.

106 Middle cerebral artery was occluded for 12 to 60 minutes in mice.

107 g coronary artery of 19 female farm pigs was occluded for 90 minutes with consecutive reperfusion.

108 ders, where parts of the vascular system are occluded for the first and the whole tumour vasculature

109 ucleopolyhedrovirus (AcMNPV) begins when the occluded form of the virus disassembles in the midgut an

110 o 4 helices, and (4) hepcidin binding should occlude Fpn and interfere with iron export independently

111 jects to be observed when partially or fully occluded from direct view, by analysing indirect diffuse

112 al a relatively open active site potentially occluded from solvent through domain motion.

113 tantly, some of the objects in the grid were occluded from the director's (but not the participant's)

114 ition of the groove from membrane-exposed to occluded from the membrane involves the repositioning of

115 ice, however, LTP was impaired in a way that occluded further reduction by heterosynaptic metaplastic

116 Importantly, CD4bs-occluded gp140 antigen induced superior B-cell and ADCC

117 nosorbent spot (ELISpot) assays of the CD4bs-occluded group increased earlier (P = 0.025) during the

118 tial memory and exploration behavior in both occluded groups.

119 the transported cations become transitorily occluded (i.e. trapped within the enzyme).

120 Lastly, long days occluded IGF2-induced improvements in recognition memory

121 On the other hand, the transmembrane pore is occluded in a remarkably similar manner in both structur

122 one TMAda(+) occluded per cage and Na(+) co-occluded in an amount linearly proportional to the numbe

123 ion reveals collateral supply to the briefly occluded in comparison to the patent radial artery of 0.

124 nd that SK-dependent intrinsic plasticity is occluded in conditioned, but not pseudoconditioned mice.

125 es in MNCs of sham rats, but this effect was occluded in RVH rats, thus equalizing the magnitude and

126 binding site formed by BBS1 and BBS7 that is occluded in the inactive state.

127 The epitope, occluded in the pre-fusion form of HA, is at the contact

128 In all experiments, the flow chamber occluded in the stenotic section.

129 14 to 34 kg (median, 18 kg) kg of whom 4 had occluded inferior vena cava or iliac veins and 2 had pre

130 nucleotide-bound state, high-energy outward-occluded intermediate state, with a defined ligand bindi

131 CC caused crystal clots occluding intrarenal arteries and a dose-dependent drop

132 onformations, the so-called outward, outward-occluded, inward-occluded, and inward GLUT1 conformation

133 racellular selectivity filter and sterically occluding ion conduction.

134 nted ability of hepcidin and its agonists to occlude iron transport may facilitate the development of

135 inding of PARP1 to single-strand DNA breaks, occluding its Erk binding sites, suppressed IEG expressi

136 tricellular vertices were identified only at occluding junctions, with none known at adherens junctio

137 s the cellular immune response by modulating occluding-junctions at the hematopoietic niche.

138 Occluding-junctions form a permeability barrier that reg

139 Our results reveal a novel role for occluding-junctions in regulating niche-hematopoietic pr

140 lineated by a walled-off central cavity with occluded lateral pore fenestrations.

141 This potentiation occludes long-term potentiation, which could be rescued,

142 injections of Delta(9)-tetrahydrocannabinol occluded LTD compared with vehicle injections; however,

143 er, light stimulation of optoFGFR1 partially occluded LTP in a Nlgn1-dependent manner.

144 terial remodeling, progressive inflammation, occluded lumens, and less frequently intestinal necrosis

145 All subjects had an occluded major epicardial artery (thrombolysis in myocar

146 lity are important determinants not only for occluding many epitopes but also for conferring resistan

147 is study, a permanent middle cerebral artery occluded (MCAO) rat model was used.

148 ferences in quantal size between control and occluded mice.

149 s, we identified the nucleotide bases in the occluding mRNA 3'UTR that interact with MIR200C-3p.

150 to an azimuthal location where it sterically occludes myosin binding sites along the thin filament su

151 he various conflicting literature reports of occluded nanoparticles being either confined to surface

152 at mimic such surface features (carbohydrate-occluded neutralization epitopes or CONE) of Env through

153 ut not postsynaptic, loss of vti1a and VAMP7 occludes NMDAR antagonist-induced synaptic potentiation

154 Successful recognition of partially occluded objects is presumed to involve dynamic interact

155 dating the locations of varying set sizes of occluded objects that swapped places a number of times.

156 nformational differences observed in the ion-occluded OF and IF states can account for diversifying t

157 BCR knockdown occludes OGD-induced Rac1 activation in hippocampal neur

158 ping revealed conserved epitopes, which were occluded on the virion or partially exposed, allowing fo

159 index <0.7 was 89.7% sensitive in diagnosing occluded or significantly stenotic tibial artery disease

160 disrupt this self-organization by sterically occluding or sequestering MinCDE from the plasma membran

161 l properties of silt and clay particles that occlude organic matter from microbial attack.

162 stablish the proximities and interactions of occluded OSDAs.

163 m inside pancreatic ducts in humans and mice occluding pancreatic ducts and thereby driving pancreati

164 mounts of organic matter have accumulated in occluded particulate organic matter ( 20%; oPOM); howeve

165 loor, bulk mineral soil, as well as free and occluded particulate organic matter.

166 s of TMAda(+) and Na(+) contain one TMAda(+) occluded per cage and Na(+) co-occluded in an amount lin

167 restingly, prior activation of these betaARs occluded PF-PC LTP, while the beta1AR antagonist metopro

168 to moderate, but not mild, arterial hypoxia occludes plasticity expression, indicating that concurre

169 ing that concurrent induction of iMF and LTF occludes plasticity.

170 The antagonist AZ8838 binds in a fully occluded pocket near the extracellular surface.

171 pound paclitaxel (Taxol) bound in a central, occluded pocket.

172 Whether early detection of occluded potential culprit arteries leads to interventio

173 xcitatory presynaptic neurotransmission that occluded presynaptic but not postsynaptic LTP.

174 og, AcrIIA2b, prevent Cas9 binding to DNA by occluding protein residues required for DNA binding.

175 Occluded pulmonary blood vessels with vascular thrombi o

176 previous studies showed that K(+)- and Rb(+)-occluded reaction intermediates are similar.

177 ccupy large portions of the visual field and occlude regions of the background optic flow that are mo

178 ron regulatory factor 1 (IRF1) expression by occluding RelA and IRF3 access to the promoter.

179 d epitope regions on Env, which are somewhat occluded relative to the exposed variable epitopes.

180 ges from our data posits a proton-bound, but occluded, resting state.

181 The other four V(H)Hs also penetrated/occluded RTA's active site, but lacked sufficient bindin

182 iver transplantation (LDLT) because they can occlude secondary branch biliary ducts when placed above

183 intervention, illustrating the course of the occluded segment and possible obstacles in the way.

184 is limited by the inability to visualize the occluded segment and requires a dual injection approach

185 crease in basal neuronal excitability, which occludes serotonin-induced enhanced excitability.

186 s of the animal visual system to degraded or occluded shapes may also give rise to an interesting phe

187 onset and displays stronger selectivity for occluded shapes.

188 by enhancing V4 responses and selectivity to occluded shapes.

189 eral occlusion produced damage mainly in the occluded side.

190 artery vessels were classified as completely occluded, significantly stenosed (>/=50%), or patent (<5

191 nths) identified a target from two partially occluded similar (for example, elephant versus bear) or

192 ers bind ssDNA in several modes differing in occluded site size and cooperativity.

193 s bind ssDNA in several modes that differ in occluded site size and cooperativity.

194 or group HOXC9 had a greater ability to bind occluded sites than the posterior HOXC10, producing diff

195 ing electronic microscopic analysis revealed occluded sites with mineral deposition of intratubular d

196 ower ssDNA binding affinities can access the occluded ssDNA and remodel individual DBDs to replace RP

197 kApcT, has recently been solved in an inward-occluded state and allows an opportunity to examine how

198 115 is likely to be protonated in the inward-occluded state and deprotonated in the inward-open state

199 ns, we observed a transition from the inward-occluded state captured in the crystal structure to a mu

200 ATP binding leads to formation of an occluded state with the substrate trapped in the trans-m

201 stabilization of the Ca(2+) sites in a more occluded state, hence displaying slowed dynamics.

202 ho84 from an open, inward-facing state to an occluded state.

203 y HDX patterns, revealing that the ion-bound/occluded states are much more stable (rigid) in the OF t

204 ectron cryomicroscopy structures of CLC-7 in occluded states by itself and in complex with OSTM1, det

205 lodurans, have been resolved in novel inward-occluded states, with the extracellular vestibule closed

206 techniques into those that use catheters to occlude straight saphenous axes (thermal / non-thermal a

207 the heptameric barrel-like CP structure that occlude substrate entry pores, preventing unregulated de

208 contrast, sits atop the enzymatic pocket and occludes substrate accessibility.

209 ucts favor a closed conformation of MGL that occludes substrate recruitment.

210 nformation in which the active-site cleft is occluded supporting the requirement for an allosteric ch

211 assorted monomers, crosslinking schemes, and occluded swelling agents, but this approach yields limit

212 ements by generating tooth pressures between occluding teeth that exceed cortical bone shear strength

213 discrimination task respond more strongly to occluded than unoccluded stimuli.

214 yer buckling and centripetal displacement to occlude the arterial lumen, a mechanism revealed by biom

215 of eRF1 via its RNase H domain to sterically occlude the binding of peptidyl release factor 3 (eRF3)

216 he second additional state, GLUex rotates to occlude the channel pore.

217 ers in red cells, causing them to deform and occlude the circulation.

218 ct when using techniques that simultaneously occlude the descending aorta and open the aortic arch ve

219 assed, in part, by the G1-dCT; GIRK2 acts to occlude the effect of Ggamma, either by setting in motio

220 one observed for hydrolyzed coumarins, which occlude the entrance of the active site cavity.

221 ely compromised when body fluids and fogging occlude the lens, requiring lengthy cleaning procedures

222 s suggest that large hydrophobic side chains occlude the pore, forming a physical gate, and that chan

223 An endovascular balloon can occlude the SVC in the event of a laceration, preventing

224 ion of GluN2B in Sst interneurons blocked or occluded the antidepressant actions of ketamine and reve

225 spondingly, inhibition of TGF-beta signaling occluded the antiseizure effects of the antagomirs.

226 MBL binding occluded the autologous NAb epitope on the B41 IO-NP tri

227 To test this hypothesis, we occluded the CD4 binding site (CD4bs) of gp140 by stable

228 (<1 min) development of nacreous walls that occluded the cell lumen almost completely.

229 d by the alkylating agent, N-ethylmaleimide, occluded the effect of H(2)O(2) The H(2)O(2)-induced cur

230 ound that slice treatment with hyaluronidase occluded the effect of MMP-3 blockade on LTP, further co

231 MDA) in MNNs from both sham and HF rats, and occluded the effects of apamin in the former.

232 The peptide primarily occludes the ACP binding site of LpxA.

233 The third interface between Hda monomers occludes the active site arginine finger, blocking its a

234 In the isolated DHO, a flexible loop occludes the active site blocking the access of substrat

235 Removal of an auto-inhibitory linker that occludes the active site of the enzyme is required and s

236 with a neutralizing anti-TNF-alpha antibody occludes the boost in amplitude of glutamatergic transmi

237 ile portion of the plug domain that normally occludes the central channel of FpvAI.

238 es when one of its four N-termini enters and occludes the channel pore.

239 rodimeric coiled-coil domain that sterically occludes the complementarity-determining regions.

240 nsistent with this we find that it partially occludes the contribution of the y splice insert to agri

241 d for Mff to evoke cytochrome c release, and occludes the effect of SENP3 overexpression.

242 cations because, in the latter, the membrane occludes the effector-interacting surface.

243 blockade of Kv7 channels mimics and largely occludes the effects of APP family inactivation.

244 he C-terminal cysteine-rich domain partially occludes the enzyme active site, preventing unfettered s

245 Density, which we conclude is Avo3, occludes the FKBP12-rapamycin-binding site of Tor2's FRB

246 an outward-open conformation and completely occludes the iron efflux pathway to inhibit transport.

247 e dimer is present in solution and partially occludes the membrane-binding surfaces of annexin, sugge

248 We conjugated mu-conotoxin KIIIA, which occludes the pore of the Na(V) channels, to an analogue

249 a unique, extended structure that partially occludes the putative 16S rRNA binding surface, and sequ

250 RNAse H1 digests RNA that occludes the relevant restriction sites, thus preventing

251 he Dbl homology (DH) domain in a manner that occludes the Rho GTPase binding site, thereby suggesting

252 of a CsrA homodimer to the 5'UTR of an mRNA occludes the Shine-Dalgarno sequence, blocking ribosome

253 MO show a closed conformation that partially occludes the three binding hot-spots and suggest a facil

254 o observed that this interaction with 14-3-3 occludes the TOMM34 interaction interface with ATP-bound

255 that TRC35 binding is critical not only for occluding the Bag6 nuclear localization sequence from ka

256 arotid artery can be improved by temporarily occluding the contralateral carotid artery.

257 in the newly forming adult body by partially occluding the DA in the tail.

258 be consistently amplified by intermittently occluding the dot trajectory.

259 Here, we show that occluding the ear causes synapses at the very first stag

260 in cells and can be modulated by altering or occluding the hydrophobic pocket of NCS1.

261 ptic mu opioid receptors was responsible for occluding the LTD.

262 n force sensing, and a bundle of acyl chains occluding the permeation path above the L105 cuff.

263 nhibition is derived from glycans sterically occluding the primary binding site on a neighboring mono

264 conformation that includes the PK helix, so occluding the ribosome binding site and thus preventing

265 Contrary to expectation, a nucleosome occluding the TATA box and transcription start sites did

266 te the transcription output of the genome by occluding the underlying DNA sequences from DNA-binding

267 hese narrow vessels, transiently blocking or occluding the vessels they pass through.

268 the Pseudomonas aeruginosa RNA degradosome, occluding them from substrates and resulting in effectiv

269 rcuit, and how Delta(9)-tetrahydrocannabinol occludes this plasticity.

270 in the N-terminal domain of DnaB, presumably occluding this region from interacting with primase.

271 erapy should be administered to dissolve the occluding thrombus.

272 ther confined to surface layers or uniformly occluded throughout the host matrix and hence provides i

273 ing the protein to transition from an inward-occluded to an inward-open conformation.

274 demonstrate that the transition from inward occluded to inward open is more energetically favorable

275 ion gate, from closed with its orifice fully occluded to open with an orifice of approximately 10 A.

276 structure of the KimA homodimer in an inward-occluded, trans-inhibited conformation.

277 formation reduces dentinal fluid flow due to occluded tubules or discontinuity with primary or second

278 ATP-bound NBDs dimerize occluding two nucleotides at interfacial binding sites;

279 is phosphorylated on one or two structurally occluded tyrosine residues and a distal threonine residu

280 C (P < 0.014) in a group receiving the CD4bs-occluded vaccine compared to those of animals immunized

281 al blood samples: (1) within the core of the occluded vascular compartment and controlled by (2) caro

282 eater than 50% reperfusion of the previously occluded vascular territory was 29 of 150 (19.3%) in the

283 treatment boundaries and the position of the occluded vasculature but also the structure of individua

284 aled increased deposition of collagen in the occluded vasculature.

285 Moreover, occluded vesicles are subjected to substantial deformati

286 Recanalization of the occluded vessel is essential but not sufficient to guara

287 by tissue plasminogen activator (TPA) in an occluded vessel with a pressure gradient.

288 species, sex, co-medication, occlusion type, occluded vessel, quantification method, ischemia duratio

289 he no-reflow phenomenon after opening of the occluded vessels in patients with coronary artery diseas

290 in conversational exchanges with a visually occluded virtual marmoset.

291 that fMRI activity patterns corresponding to occluded visual information in early visual cortex fill

292 d human fMRI data while presenting partially occluded visual scenes.

293 ffect of apamin on dendritic SK channels was occluded when R-type calcium channels were blocked, indi

294 A rings, which influences their energy to co-occlude with TMAda(+) and stabilize different Al configu

295 e forms (outward-facing open, outward-facing occluded with substrate bound, and inward-facing open).

296 fts underwent thrombosis and were completely occluded within 24 to 48 hours.

297 nto the mechanisms by which additives become occluded within crystals.

298 factors (TFs) to regulatory sequences often occluded within nucleosomes.

299 f the tethered-peptide agonist stalk that is occluded within the GAIN domain in the holoreceptor form

300 Solid-state NMR shows that Asp is sparsely occluded within vaterite and calcite.