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1 s of Bor1 have rotated inwards to achieve an occluded state.
2 les of E. coli confirmed the presence of the occluded state.
3 ic conformations, yielding an outward-facing occluded state.
4 ophan binding now allows the formation of an occluded state.
5 rity-dependent structural transitions to the occluded state.
6 site from an outwardly to an inwardly facing occluded state.
7 nalized and is partially divided in an early occluded state.
8 a catalytic cycle, consistent with a genuine occluded state.
9 the transition from the outward-open to the occluded state.
10 ho84 from an open, inward-facing state to an occluded state.
11 y described structures in outward-facing and occluded states.
12 rmational transitions between the closed and occluded states.
13 n on 'inward-facing' HutCD culminates to an 'occluded' state.
14 to promote the structural transition to the occluded state, a step in the transport cycle that is de
15 kApcT, has recently been solved in an inward-occluded state and allows an opportunity to examine how
16 115 is likely to be protonated in the inward-occluded state and deprotonated in the inward-open state
18 ubstrate binding and in the formation of the occluded state and to investigate the dynamics of this s
19 binding site to generate a substrate-bound, occluded state, and non-conservative mutation of Tyr130
20 onformations, including the outward-open and occluded states, and show the transporter's engagement w
21 y HDX patterns, revealing that the ion-bound/occluded states are much more stable (rigid) in the OF t
22 substrate appears to stabilize the partially occluded state, as in the two apo simulations either no
23 ectron cryomicroscopy structures of CLC-7 in occluded states by itself and in complex with OSTM1, det
24 ns, we observed a transition from the inward-occluded state captured in the crystal structure to a mu
25 classical" system L inhibitor BCH induces an occluded state critical for transport, confirming its su
27 to 3.6 A resolution, reveals a ligand-bound occluded state for the MFS and provides new insights int
28 formation indicates that a water-impermeable occluded state (glucose and Na(+) in their binding pocke
30 (Aa), a prokaryotic NSS homolog, revealed an occluded state in which one leucine and two Na(+) ions a
31 ellular and extracellular sides and includes occluded states in which both gates are simultaneously c
32 lar dynamics simulations, we reached a fully occluded state, in which the transporter-bound 5HT becom
33 ne in an apparently open state and one in an occluded state, indicating that SemiSWEETs and SWEETs ar
36 an extracellular gate that closes to form an occluded state is strongly supported by conformational s
37 ransition between "inward-open" and solvent "occluded" states is accompanied by Na(+)-induced pinchin
40 molecular dynamics (MD) trajectories of the occluded state of the bacterial leucine transporter LeuT
41 r dynamic simulation showed that a sustained occluded state of the transporter upon binding to co-tra
43 outward-facing conformation and intermediate occluded states on a path to the inward-facing conformat
46 galactopyranosides specifically, inducing an occluded state that can open to either side of the membr
49 es transitions between a closed state and an occluded state via an intermediate "open" conformation.
50 e course of MD simulations starting from the occluded state with bound Na(+), but in the absence of s
51 ward-open character and is lower than in the occluded state with bound substrate; however, the Na1 si
53 phate transporter, PiPT, in an inward-facing occluded state, with bound phosphate visible in the memb
54 lodurans, have been resolved in novel inward-occluded states, with the extracellular vestibule closed