ライフサイエンスコーパス: occludens

1 e postsynaptic density 95/discs large/zonula occludens 1 (PDZ) domain, involved in scaffolding and si

2 r the interaction of PSD-95/Discs Large/Zona Occludens 1 (PDZ) domain-containing proteins.

3 AT1 postsynaptic density 95/Discs large/zona occludens 1 (PDZ)-interacting domain.

4 integrated component of the occludin/zonula occludens 1 (ZO-1) adhesion complex at the BTB, structur

5 s express the tight junction proteins zonula occludens 1 (ZO-1) and occludin and form a barrier with

6 e tight junctional complex, including zonula occludens 1 (ZO-1) and occludin.

7 blood-brain barrier (BBB) occludin and zona occludens 1 (ZO-1) expression were significantly decreas

8 We previously found that depleting zonula occludens 1 (ZO-1) family proteins in MDCK cells induces

9 , claudin-23 (CLDN23), occludin, and Zonulae occludens 1 (ZO-1) in primary human keratinocytes.

10 to interact with a scaffold protein, zonula occludens 1 (ZO-1), demonstrating that one claudin affec

11 on of tight-junction-associated protein zona occludens 1 (ZO-1), translocation of ZO-1 to cell-cell b

12 onship between neuronal Connexins and Zonula Occludens 1 (ZO1), an intracellular scaffolding protein

13 ins, including tight junction protein zonula occludens 1 and aquaporin 4.

14 anisms: it maintained localization of zonula occludens 1 and occludin at apical tight junctions and r

15 nd the outer limiting membrane (OLM) (zonula occludens 1 and occludin).

16 ization of the tight junction protein zonula occludens 1 and of the junction-associated actin microfi

17 e cell elongation, and alter junctional zona occludens 1 and vascular endothelial-cadherin staining.

18 Reduced zonula occludens 1 expression was observed after HbG transfusio

19 localization of CD31, beta-catenin, and zona occludens 1 in junctions between sinus cells.

20 had a small decrease in expression of zonula occludens 1 in SB mucosa and significant decreases in ex

21 in-1 protein level, relocation of the zonula occludens 1 protein (ZO-1) to the TJ, and redistribution

22 n by the disengagement of the protein zonula occludens 1 protein from the tight junctional complex.

23 Zonula occludens 1 protein redistribution after bacteria coloni

24 In contrast, zonula occludens 1 was well preserved along intercellular borde

25 DZ (postsynaptic density 95/Discs large/zona occludens 1) ligand domains that can control their synap

26 DZ (postsynaptic density 95/Discs large/zona occludens 1) protein PICK1 (protein interacting with C k

27 DZ (postsynaptic density 95/Discs large/zona occludens 1) proteins that interact with glutamate recep

28 ing MUPP1 (multi-PDZ protein-1), ZO1 (zonula occludens 1), and Af6.

29 n), apoptosis (M30), tight junctions (zonula occludens 1), and neutrophil influx (myeloperoxidase) we

30 ZO-1 (Zona occludens 1), encoded by the tight junction protein 1 (T

31 PDZ2 (postsynaptic density/Discs large/zona occludens 1), PDZ3, and PDZ4 of the PCP protein Scrb1 (S

32 DZ (postsynaptic density 95/Discs large/zona occludens 1)-domain interaction between GluR1 and SAP97,

33 f the tight junction scaffold protein zonula occludens 1, and disrupted junctional localization of th

34 Upon calcium repletion, occludin, zonula occludens 1, and E-cadherin failed to redistribute to th

35 in, plakoglobin, claudin-4, occludin, zonula occludens 1, and tricellulin were decreased at cell cont

36 , transient disruption of claudin-18, zonula occludens 1, and zonula occludens 2 localization to lung

37 ignificant decreases in expression of zonula occludens 1, claudin-1, and occludin in rectosigmoid muc

38 endothelial tight junction proteins (zonula occludens 1, claudin-5, and occludin), astrocyte activat

39 Ca2+ as revealed by the relocation of zonula occludens 1, the establishment of transepithelial electr

40 s evidenced by staining for F-actin and zona occludens 1.

41 ored the expression of E-cadherin and zonula occludens 1.

42 cts on the cytoplasmic plaque protein zonula occludens 1.

43 ROCK with the tight junction protein zonula occludens 1.

44 sion of the TJ molecules occludin and zonula occludens 1.

45 ynaptic density-95 (PSD-95)/Discs large/zona occludens-1 (PDZ) binding domain, which is present on al

46 ynaptic density-95 (PSD-95)/Discs large/zona occludens-1 (PDZ) binding motif, is localized to the pos

47 post-synaptic density-95/discs large/zonula occludens-1 (PDZ) domain of the human protein tyrosine p

48 the postsynaptic density-95/Discs large/zona occludens-1 (PDZ) domain protein interacting specificall

49 st synaptic density, discs large, and zonula occludens-1 (PDZ) domain protein SAP97 is a component of

50 g postsynaptic density-95/disks large/zonula occludens-1 (PDZ) domain-containing protein melanoma dif

51 protein of 95 kilodaltons, disc large, zona occludens-1 (PDZ) domain-containing proteins appear most

52 mediated signals and PSD-95-discs large-zona occludens-1 (PDZ) domain-dependent signals are required

53 Postsynaptic density 95/discs large/zonus occludens-1 (PDZ) domain-interacting motifs, in addition

54 post-synaptic density-95/discs large/zonula occludens-1 (PDZ) domain.

55 two postsynaptic density 95/disks large/zona occludens-1 (PDZ) domains and a tail ending in an ezrin-

56 ng postsynaptic density 95/disc large/zonula occludens-1 (PDZ) domains have been shown to play critic

57 10 post-synaptic density-95/Discs Large/zona occludens-1 (PDZ) domains of PATJ could bind to the carb

58 two postsynaptic density-95/Discs large/zona occludens-1 (PDZ) domains of the scaffolding protein PSD

59 ng protein containing five PSD95/dlg/zonular occludens-1 (PDZ) domains that tether NORPA (phospholipa

60 postsynaptic density 95, discs large, zonula occludens-1 (PDZ) domains to engage the transport mechan

61 which is separate from the PSD95/dlg/zonular occludens-1 (PDZ) interacting domain.

62 ynaptic density-95 (PSD-95)/discs large/zona occludens-1 (PDZ) interaction to AMPA receptor (AMPAR)-b

63 ts carboxyl-terminal PSD-95/Discs Large/Zona Occludens-1 (PDZ) ligand and binding of the PDZ domain-c

64 s a postsynaptic density-95/Discs large/zona occludens-1 (PDZ) ligand, which is absent in EAAT2a.

65 a Postsynaptic density 95, Disk large, Zona occludens-1 (PDZ) motif.

66 in interactions with PSD-95/discs large/zona occludens-1 (PDZ) motifs.

67 ith postsynaptic density-95/discs large/zona occludens-1 (PDZ) proteins via a C-terminal PDZ binding

68 roteins that contain PSD-95-Discs Large-zona occludens-1 (PDZ), Src homology 3, and guanylate kinase

69 stsynaptic density (PSD)-95/discs large/zona occludens-1 (PDZ)-containing proteins that can assemble

70 ts postsynaptic density 95, disk large, zona occludens-1 (PDZ)-dependent binding (PDZ(-)) produced a

71 naptic density protein 95/disks large/zonula occludens-1 (PDZ)-domain proteins and A-kinase anchoring

72 and postsynaptic density-95/Discs large/zona occludens-1 (PDZ)] protein erbin and delta-catenin, a co

73 c density-95 (PSD-95)/discs large (Dlg)/zona occludens-1 (ZO-1) (PDZ) binding sites but lacks the cen

74 in ring (PAMR), and redistribution of zonula occludens-1 (ZO-1) and cadherins.

75 on, we investigated the expression of zonula occludens-1 (ZO-1) and E-cadherin, two molecules associa

76 roscopy using the tight junction marker zona occludens-1 (ZO-1) and end-binding protein-1 (EB-1), whi

77 rier using the tight junction markers zonula occludens-1 (ZO-1) and occludin.

78 ession of TJ transcripts, claudin-11, zonula-occludens-1 (ZO-1) and tricellulin in human SC endotheli

79 retention of Cx43 scaffolding protein Zonula Occludens-1 (ZO-1) at cell surfaces, suggesting that ZO-

80 e steady-state levels of occludin and zonula occludens-1 (ZO-1) at the BTB site via the p38 MAP kinas

81 e steady-state levels of occludin and zonula occludens-1 (ZO-1) at the BTB via the p38 mitogen activa

82 tion against IL-1beta-induced loss of zonula occludens-1 (ZO-1) at the tight junctions and alteration

83 We found that the accumulation of Zonula Occludens-1 (ZO-1) at TJs closely scales with tension of

84 Zonula occludens-1 (ZO-1) binds the carboxy terminus of Cx43, a

85 ced podocyte tight junctional protein zonula occludens-1 (ZO-1) but did not affect its mRNA level.

86 (TJ)-associated proteins occludin and zonula occludens-1 (ZO-1) following stimulation of brain microv

87 e and threonine residues, we screened zonula occludens-1 (ZO-1) immunoprecipitates for the existence

88 proteins) have been co-localized with zonula occludens-1 (ZO-1) in the tight junction of epithelial c

89 Src can disrupt the connexin43 (Cx43)-zonula occludens-1 (ZO-1) interaction, leading to down-regulati

90 ark of polarized epithelial cells and zonula occludens-1 (ZO-1) is a known key regulator of tight jun

91 Zonula occludens-1 (ZO-1) is a submembrane scaffolding protein

92 levels, the tight junctional protein Zonula Occludens-1 (ZO-1) is distributed intracellularly in gra

93 a marked decrease in beta-catenin and zonula occludens-1 (ZO-1) localization to the intercalated disc

94 and rhesus macaques exhibited loss of zonal occludens-1 (ZO-1) staining, indicative of a compromised

95 binds to the Cx43 scaffolding protein zonula occludens-1 (ZO-1) with a higher affinity than does Cx43

96 The scaffold protein zonula-occludens-1 (ZO-1), a member of the MAGUK family of prot

97 ents yielded several proteins including zona occludens-1 (ZO-1), a structural protein previously iden

98 ression of TTF-1, aquaporin-5 (AQP5), zonula occludens-1 (ZO-1), and cytokeratins.

99 lex with established interaction with zonula occludens-1 (ZO-1), and was building homophilic cis- and

100 o assay for the presence of occludin, zonula occludens-1 (ZO-1), cadherin-5, and beta-catenin.

101 d known junctional proteins including zonula occludens-1 (ZO-1), occludin, and claudin-5.

102 l-cell contacts in close proximity to zonula occludens-1 (ZO-1), oxLDL treatment induced a disorganiz

103 ate tight-junction-associated protein Zonula Occludens-1 (ZO-1), which in turn plays a critical role

104 e BBB-related tight junction protein, Zonula occludens-1 (ZO-1).

105 unction proteins such as occludin and zonula occludens-1 (ZO-1).

106 the tight junction-associated protein zonula occludens-1 (ZO-1).

107 tight junction proteins, occludin and zonula occludens-1 (ZO-1).

108 another element of the E-cad complex, zonula occludens-1 (ZO-1).

109 ction membrane proteins, occludin and zonula occludens-1 (ZO-1).

110 herin and tight junction (TJ) protein Zonula Occludens-1 (ZO-1).

111 e BRB-related tight junction protein, Zonula occludens-1 (ZO-1).

112 c density-95 (PSD-95)/Discs large (Dlg)/zona occludens-1 (ZO-1)] binding domain and localizes to the

113 first two PDZ [PSD-95/Discs large (Dlg)/zona occludens-1 (ZO-1)] domains is necessary and sufficient

114 c density-95 (PSD-95)/Discs large (Dlg)/zona occludens-1 (ZO-1)] interactions with members of the PSD

115 c density-95 (PSD-95)/Discs large (Dlg)/zona occludens-1 (ZO-1)] proteins via its C-terminal PDZ-bind

116 ts, the tight junction protein 1 (TJP1)/Zona Occludens-1 (ZO1), and microtubule associating protein i

117 s-1 mRNA are co-localized apically and zonal occludens-1 3' untranslated region-binding sites for CPE

118 tty-acid binding protein [I-FABP] and zonula occludens-1 [ZO-1]) and microbial translocation (lipopol

119 phoprotein 50) is a PSD-95, disc large, zona occludens-1 adapter that acts as a scaffold for signalin

120 The junctional proteins zonula occludens-1 and beta-catenin stained positively in both

121 amethasone-stimulated localization of zonula occludens-1 and beta-catenin to sites of cell-cell conta

122 zed mammary epithelial cells, in which zonal occludens-1 and claudin-3, apical tight-junction protein

123 n and the tight junction (TJ) proteins, zona occludens-1 and occludin, and the loss of the endothelia

124 nd tight-junction-associated proteins zonula occludens-1 and occludin.

125 s of tight junction proteins, such as zonula occludens-1 and Occludin.

126 alterations in the adherens junctions zonula occludens-1 and partitioning defective 3, reduced polari

127 hat postsynaptic density-95/discs large/zona occludens-1 and Src homology 3 domain-binding motifs loc

128 ng upregulation of dermal N-cadherin, Zonula Occludens-1 and the gap junction protein Connexin43 (Cx4

129 acellular flux, and redistribution of zonula occludens-1 and VE-cadherin but failed to induce apoptos

130 from mammary epithelial cells disrupts zonal occludens-1 apical localization and tight-junction distr

131 Connexin43 (Cx43) and zona occludens-1 are improperly localized in Akap9 mutant tes

132 RMP) homology, and PSD-95, Discs large, zona occludens-1 binding domains.

133 postsynaptic density-95, discs large, zonula occludens-1 binding motif in the C terminus of KV1.2alph

134 rge gap junction plaques, had reduced zonula occludens-1 binding, and displayed increased stability.

135 In addition, zonula occludens-1 co-localized with Muller cells within the co

136 esion via its effects on the occludin-zonula occludens-1 complex.

137 of epithelial markers E-cadherin and Zonula occludens-1 decreased while expression of mesenchymal ma

138 ion with both endogenous occludin and zonula occludens-1 demonstrating that exogenous occludin correc

139 minin, endothelial barrier antigen, and zona occludens-1 diminished in the ipsilateral cortex, sugges

140 synaptic density protein-95/discs large/zona occludens-1 domain (PDZ).

141 ynaptic density-95 (PSD-95)/Discs large/zona occludens-1 domain of the distantly related membrane-ass

142 ERF1 postsynaptic density 95/disc-large/zona occludens-1 domain.

143 and postsynaptic density-95/Discs large/Zona Occludens-1 domains found in X11alpha and mLin-2/CASK bi

144 ing PostSynaptic Density-95/Discs large/Zona Occludens-1 domains, is an ortholog of the Drosophila tu

145 ytokine-induced hyperpermeability and zonula occludens-1 downregulation in NS-398-treated C2BBe1 cell

146 suppressed epithelial E-cadherin and zonula occludens-1 expression.

147 M-induced AR, with lower occludin and zonula occludens-1 expression.

148 permeability and reduced occludin and zonula occludens-1 expression.

149 (postsynaptic density-95/discs-large /zonula occludens-1 homology) motif SSAV, and yeast Saccharomyce

150 ted with an increase in claudin-5 and zonula occludens-1 immunofluorescence at cell-cell contracts.

151 ng mammary ducts, depletion of CPEB or zonal occludens-1 impairs central cavity formation, indicating

152 ssociated with a potent protection of zonula occludens-1 linear border pattern in endothelial cells.

153 y, ectopic expression of CPEB enhances zonal occludens-1 localization.

154 Zonula occludens-1 molecules are also highly dynamic in this re

155 CPEB and zonal occludens-1 mRNA are co-localized apically and zonal occ

156 rescued when they are transduced with zonal occludens-1 mRNA containing, but not lacking, CPEB-bindi

157 ur data demonstrate that CPEB-mediated zonal occludens-1 mRNA localization is essential for tight-jun

158 osophila disc large tumor suppressor, zonula occludens-1 protein (PDZ) consensus binding motif at its

159 a disc large tumor suppressor (Dlg1), zonula occludens-1 protein (zo-1) (PDZ) domain proteins.

160 orylation regulates the known role of zonula occludens-1 protein (ZO-1) in gap junction (GJ) function

161 ion, immunofluorescent assessments of zonula occludens-1 tight junction protein cellular distribution

162 d podocyte dysfunction, as evidenced by zona occludens-1 translocation to the membrane.

163 associated protein and MMP-9 substrate zonae occludens-1 was degraded after ischemia, but this was re

164 TJ complex proteins claudin-1 and zonula occludens-1 were upregulated following TLR2 stimulation,

165 tsynaptic density-95)/Discs large/ZO-1 (zona occludens-1) (PDZ) domain-containing protein, erbin, in

166 Z (postsynaptic density 95, Disk large, Zona occludens-1) adaptor protein synectin was essential for

167 ction proteins (occludin, claudin-1 and zona occludens-1) are internalized through an NF-kappaB-depen

168 DZ (postsynaptic density-95/Discs large/zona occludens-1) binding domain interactions and triggers pr

169 DZ (postsynaptic density-95/Discs large/zona occludens-1) binding domain, which interacts with Tamali

170 The PDZ (PSD-95, discs large, zona occludens-1) binding motif at the distal end of the NR2

171 DZ (postsynaptic density-95/Discs large/zona occludens-1) domain independent and is regulated by alte

172 DZ (postsynaptic density-95/Discs large/zona occludens-1) domain proteins that target AMPA receptors

173 DZ (postsynaptic density-95/discs large/zona occludens-1) domain-based interactions play important ro

174 DZ (postsynaptic density-95/Discs large/zona occludens-1) domain-binding consensus at their C termini

175 hapsyn-110 is a PDZ (PSD-95/Discs large/zona occludens-1) domain-containing membrane-associated guany

176 DZ (postsynaptic density-95/Discs large/zona occludens-1) domain-containing protein interacting with

177 postsynaptic density 95, discs large, zonula occludens-1) domains and other regions.

178 (postsynaptic density 95/discs large/zonula occludens-1) domains are believed to provide relatively

179 (post-synaptic density-95/discs large/zonula occludens-1) domains are small, protein-protein binding

180 ough two of its PDZ (PSD-95/Discs large/zona occludens-1) domains as well as intact N-terminal and gu

181 ost-Synaptic Density-95, Discs Large, Zonula Occludens-1) domains followed by a short carboxyl-termin

182 ynaptic density-95 (PSD-95)/Discs large/zona occludens-1) domains that bind the synaptic scaffolding

183 on and the first two PDZ (PSD-95, Dlg1, zona occludens-1) domains, the PDZ3 and guanylate kinase doma

184 tight junction protein (occludin and zonula occludens-1) expression.

185 by several PDZ (PSD-95, discs large, zonula occludens-1) proteins, which mediate protein-protein int

186 DZ (postsynaptic density-95/Discs Large/zona occludens-1) scaffold protein, INAD (inactivation no aft

187 in 43), Cx45 (connexin 45), and ZO-1 (zonula occludens-1) were identified as novel mRNA targets of FX

188 DZ (postsynaptic density 95/discs large/zona occludens-1), and Src homology 3 domains.

189 DZ (postsynaptic density-95/Discs large/zona occludens-1), Src homology 3, and guanylate kinase domai

190 DZ (postsynaptic density-95/Discs large/zona occludens-1)-binding kinase/T-LAK (lymphokine-activated

191 DZ (postsynaptic density-95/Discs large/zona occludens-1)-containing protein dX11/Mint/Lin-10, which

192 etase, expressed by Muller cells, and zonula occludens-1, a tight-junction protein.

193 kdown of Cx43 and N-cadherin, but not Zonula Occludens-1, accelerated cell migration in a scratch wou

194 d levels of alanine aminotransferase, zonula occludens-1, and interleukin-1beta compared with HS/CR a

195 phragm-associated protein P-cadherin, zonula occludens-1, and nephrin, a change consistent with loss

196 id (pyd), the Drosophila homologue of Zonula Occludens-1, are characterized by two phenotypes visible

197 duction of the tight-junction molecules zona occludens-1, claudin 3, and claudin 5 and other pathways

198 ly affected the tight junction proteins zona occludens-1, claudin-1, and claudin-5, which were signif

199 teins, including occludin, claudin-5, zonula occludens-1, junctional adhesion molecule-A, and endothe

200 bstrates of matrix metalloproteinase-9 (zona occludens-1, laminin), tissue inhibitor of matrix metall

201 o, in addition to loss of nephrin and zonula occludens-1, mesenchymal markers such as desmin, fibrobl

202 thelial cells such as cytokeratin 18, zonula occludens-1, mucins-1 and -2, antigen A33, and dipeptidy

203 ession of the tight junction proteins zonula occludens-1, occludin, and claudin-1 in the ileum follow

204 s target genes FGF19 and TJ proteins zonula, occludens-1, occludin, and claudin-1, along with increas

205 ssion of junctional proteins, such as zonula occludens-1, occludin, and claudin-4.

206 entative tight junction proteins (ie, zonula occludens-1, Occludin, Claudin-1) that critically regula

207 e expression of tight junction proteins zona occludens-1, occludin, claudin-1, and claudin-4, as well

208 acer permeability, junctional protein zonula occludens-1, occludin, claudins and E-cadherin expressio

209 ostsynaptic density (PSD)-95/Disc Large/Zona Occludens-1, Src homology 3, and guanylate kinase-like d

210 nd reduced expression of E-cadherin and zona occludens-1, whereas collagen-I and alpha-smooth muscle

211 er integrity and tight junction protein zona occludens-1, while the result for cells infected with th

212 e postsynaptic density-95/discs large/zonula occludens-1-and WW domain-containing scaffold protein ca

213 the postsynaptic density-95/Discs large/zona occludens-1-binding domain of PTEN.

214 Cavity formation in zonal occludens-1-depleted cells is rescued when they are tran

215 post-synaptic density-95/discs large/zonula occludens-1-domain-containing (PDZ) proteins and serines

216 laminin, and the tight junction protein zona occludens-1.

217 , junctional adhesion molecule-A, and zonula occludens-1.

218 ning of the TJ molecules occludin and zonula occludens-1.

219 ctor 3, Toll-interacting protein, and zonula occludens-1.

220 n kinase and increasing expression of zonula occludens-1.

221 n kinase and increasing expression of zonula occludens-1.

222 Zonula occludens-1/NF-kappaB/CXCL8: a new regulatory axis for t

223 ynaptic density-95 (PSD-95)/Discs large/zona occludens-1] domains of membrane-associated guanylate ki

224 rminus with the PDZ [PSD-95/Discs large/zona occludens-1] domains of PSD-95.

225 ynaptic density-95 (PSD-95)/Discs large/zona occludens-1] domains of PSD-95/SAP90 (synapse-associated

226 DZ [postsynaptic density-95/Discs large/zona occludens-1]-domain containing protein, protein interact

227 of the blood-brain barrier (claudin 5a, zona occludens 1a and b).

228 silencing of the tight junction protein zona occludens 2 (ZO-2 KD) induces cell hypertrophy by two me

229 Zona occludens 2 (ZO-2) has a dual localization.

230 f claudin-18, zonula occludens 1, and zonula occludens 2 localization to lung tight junctions in situ

231 nd protein for claudin-5, occludin, and zona occludens 2 were also reduced in infected cells.

232 nction proteins (claudin 1, 14, 16, and zona occludens 2), nine gap junction proteins (connexin 26, 3

233 Zonula occludens-2 (ZO-2) is a tight junction (TJ) cytoplasmic

234 its PDZ-binding motif to interact with zona occludens-2 (ZO-2) protein, which promotes YAP's translo

235 cally interact with the protein ZO-2 (zonula occludens-2).

236 of inositol pentakisphosphate 2-kinase, zona occludens 3, and FAT tumor suppressor 2).

237 ranule-like cytoplasmic structures, and zona occludens 3.

238 n interact with the carboxyl termini of zona occludens-3 (ZO-3) and claudin 1, respectively.

239 dissolution of some tight junctions (zonula occludens) and zonula adherens without loss of desmosome

240 ochemistry showed that E-cadherin and Zonula occludens are down-regulated in MCF-7/CXCR4-DeltaCTD cel

241 Staining for the zonula occludens complex (ZO-1) and adherens complex (alpha, be

242 in, Crumbs, and two PSD95/discs large/zonula occludens domain proteins, protein associated with Lin s

243 DZ (postsynaptic density 95/discs large/zona occludens) domain AMPAR-binding protein, is bidirectiona

244 he His-ZO-1-PDZ1 (first PDZ domain of zonula occludens) domain that binds Neph1-CD was also analyzed

245 0, a postsynaptic density 95/disc-large/zona occludens-domain containing protein: GLR-1 accumulates i

246 postsynaptic density-95, discs large, zonula occludens) domains play a general role in recruiting rec

247 RHL2 and the junction proteins (e.g., zonula occludens, E-cadherin, claudins, and occludin).

248 The scaffold proteins of the zonula occludens family are required for the correct localizati

249 subapical region overlapping with ZO-1 (zona occludens-I), a key component of the TJ.

250 The tight junction, or zonula occludens, is a specialized cell-cell junction that regu

251 is accomplished in vertebrates by the zonula occludens, or tight junction.

252 inal postsynaptic density 95/disc-large/zona occludens (PDZ) binding domain increased its range by ap

253 inal postsynaptic density 95/disc-large/zona occludens (PDZ) binding motif.

254 the postsynaptic density-25/Discs large/zona occludens (PDZ) domain of RIM.

255 tes interactions with PSD-95/disc large/zona occludens (PDZ) domain-containing proteins.

256 The first two PSD-95/disks large/zona occludens (PDZ) domains of PSD-95 have been shown to be

257 lti-postsynaptic density-95/discs large/zona occludens (PDZ) protein that binds to the glutamate rece

258 are postsynaptic density 95/disc-large/zona occludens (PDZ)-domain-containing scaffolding proteins f

259 ls, because the presence of an intact zonula occludens prevented passage.

260 tigen 2), blood-retinal barrier [anti-zonula occludens protein 1 (ZO-1) and anti-occludin], and hypox

261 IV, laminin, claudin-5, occludin, and zonula occludens protein 1 was also better preserved in neonata

262 Drosophila discs large protein, and the zona occludens protein 1).

263 vious change of claudin-1, claudin-4, zonula occludens protein 1, and zonula occludens protein 2 expr

264 in-4, zonula occludens protein 1, and zonula occludens protein 2 expressions was observed.

265 PDZ (postsynaptic density/disc large/zonula occludens) protein binding assays, that these soluble pr

266 PDZ (postsynaptic density 95/disc large/zona occludens) protein that assembles macromolecular complex

267 binds to the N-terminal PDZ domain of zonula occludens proteins (PDZ1).

268 Zonula occludens proteins are multidomain proteins usually loca

269 cludin but no change in expression of zonula occludens proteins ZO-1 and -2.

270 chanical tension: the tight junction (zonula occludens), the zonula adherens (ZA), and the macula adh

271 cells, this complex localizes to the zonula occludens (tight junctions) and appears to regulate epit

272 Zonula occludens toxin (Zot) is an enterotoxin elaborated by Vi

273 these structures can be modulated by Zonula occludens toxin (Zot).

274 The intestinal secretion induced by zonula occludens toxin follows the opening of tight junctions c

275 Zonula occludens toxin induced a time- and dose-dependent decre

276 Zonula occludens toxin is a novel toxin elaborated by Vibrio ch

277 e tissues were also fixed, exposed to zonula occludens toxin, and processed for fluorescence microsco

278 ells is regulated by tight junctions (zonula occludens), we wished to determine whether they also reg

279 tural and functional integrity of the zonula occludens (ZA) induced by ATP depletion of renal tubular

280 We have determined that the zonula occludens (ZO) family of TJ plaque proteins sequesters c

281 of this barrier are dependent on the zonula occludens (ZO) membrane-associated guanylate kinase (MAG

282 The zonula occludens (ZO) protein-1 is a membrane-associated compon

283 Zona occludens (ZO) proteins are molecular scaffolds localize

284 Thus the manner in which the zonula occludens (ZO) proteins multimerize has implications for

285 Specific TJ proteins, such as zonula occludens (ZO) proteins, localize not only at the cell-c

286 f these junctions is dependent on the zonula occludens (ZO) proteins, members of the membrane-associa

287 The zonula occludens (ZO) subfamily of membrane-associated guanylat

288 The zonula occludens (ZO)-1 and -2 proteins have context-dependent

289 Zonula occludens (ZO)-1 is a member of the MAGUK (membrane-asso

290 The tight junction (TJ) protein zonula occludens (ZO)-1 links the intracellular domain of TJ-tr

291 Here, we show that zonula occludens (ZO)-1 localizes preferentially to the periphe

292 junction proteins, namely, occludin, zonula occludens (ZO)-1, and ZO-2 in the caveolar fraction of H

293 on of occludin, claudin-1, claudin-5, zonula occludens (ZO)-1, and ZO-2, and a TJ accessory protein a

294 tide exchange factor (GEF) 2, but not zonula occludens (ZO)-1, in epithelial cells, and these interac

295 the distribution of the TJ proteins, zonula occludens (ZO)-1, ZO-2, and cingulin, examination of the

296 ion molecule-A (JAM)-A, occludin, and zonula occludens (ZO)-1.

297 ite of arachidonic acid, by stimulating zona occludens (ZO)-2 tyrosine phosphorylation and its dissoc

298 In cell culture zonula occludens (ZO)-family proteins are important for assembl

299 ant disruption of actin filaments and zonula occludens (ZO-1), and a decrease in transepithelial resi

300 on components [Occludin, Claudin-1, -2, Zona occludens (ZO-1, -2)].