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1 ci, often in the absence of CTCF and cohesin occupancy.
2 fer in terms of the TAR conformation and ARG occupancy.
3 ations of tropical versus non-tropical niche occupancy.
4 hiometries, binding energetics and WW domain occupancy.
5 reprograming through changes in its promoter occupancy.
6 presence of Kin28 has little effect on Taf1 occupancy.
7 BRG1 and BRM showed minimal effect on NIPBL occupancy.
8 rative manner, enabling a mutual increase in occupancy.
9 and fine control of the target site's basal occupancy.
10 iated with PU.1, CEBPB, TFE3, JUN, and FOSL2 occupancy.
11 erates on pMHCII complexes with full peptide occupancy.
12 ng, and single-molecule transcription factor occupancy.
13 hytes and lichens group increased in average occupancy.
14 adaptive immune cells swiftly induced NIPBL occupancy.
15 o the live mouse brain and used to report TF occupancy.
16 control cerebellar granule neurons (CGN) GZ occupancy.
17 ather than insufficient dopamine D2 receptor occupancy.
18 yophytes and lichens, measured as changes in occupancy.
19 eveal global changes in histone modification occupancy.
20 tality, and on intensive care unit (ICU)-bed occupancy.
21 uring neurogenesis, revealing Ebp1 as a high-occupancy 60S peptide tunnel exit (TE) factor during pro
23 hment and strikingly uneven local polymerase occupancy along the rDNA, indicating substantial variati
26 multiple AGO proteins, we examined both the occupancies and binding affinities of miRNA-AGO2 complex
27 ]-(+)-PHNO to measure D(2) and D(3) receptor occupancy and [(11)C]CUMI101 to measure 5-HT(1A) occupan
28 ort 2 received [(11)C]MDL100907 for 5-HT(2A) occupancy and [(11)C]DASB for SERT occupancy; Cohort 3 u
29 ta of 1,075 poisoned red kites to changes in occupancy and abundance across 274 sites (10 x 10-km squ
31 e. connectivity) in predicting habitat patch occupancy and colonization, while patch centrality (conn
32 s, as well as in polycomb repressive complex occupancy and CTCF binding sites are associated with can
33 lectively, these data show that differential occupancy and efficacy at three discrete neurosteroid-bi
34 ross subjects, a subset of PTMs display high occupancy and frequency for AD, suggesting importance in
39 +1 nucleosome, the combination of low TFIIH occupancy and high occupancy of the transcription elonga
40 cruitment to chromatin and lead to decreased occupancy and increased acetylation of histones within g
41 -mobility group protein Nhp6 reduces histone occupancy and increases chromatin movement, decompaction
44 performed nanopore sequencing of nucleosome occupancy and methylome (nanoNOMe) on four human cell li
46 but instead is additionally dependent on the occupancy and orientation of the metal ion's d-orbitals
47 hromatin openness in concert with nucleosome occupancy and placement of histone modifications facilit
49 ocol to visualize the density of trait space occupancy and thoroughly test for the existence of macro
50 relative toxin strengths, initial fractional occupancies, and spatial patterns affect the maintenance
52 otations of genome-wide transcription factor occupancy, and identified 378 significant enrichments ac
54 lean cytochrome P450 profile, in vivo target occupancy, and promise for further lead optimization.
55 s of de novo BTK synthesis, which determines occupancy, and the relationship between occupancy, pathw
56 hereby the reversal potential determines ion occupancy, and thus, conductivity, of the selectivity fi
57 t specific genes correlates with high H2Bub1 occupancy, and with promoter-proximal RNAPII pausing.
60 al variants that affect transcription factor occupancy are nearly evenly partitioned between loss- an
62 sible covalent BTK PROTAC with a high target occupancy as its corresponding kinase inhibitor and effe
63 IID, Taf1 and Taf4, similarly show increased occupancy as measured by ChIP upon depletion or inactiva
64 with distinct dwell times and relative cell occupancy as readouts, which may be useful to probe cell
65 the ordering of magnetic moments or orbital occupancies at low temperatures, which is especially rel
67 -type protein, ENL mutants exhibit increased occupancy at a subset of targets, leading to a marked in
68 , and transcription elongation promote NIPBL occupancy at active enhancers while the induction of NIP
69 infections, and that restricting the maximum occupancy at each point of interest is more effective th
70 ined H3K27ac abundance and facilitated NIPBL occupancy at enhancers and that active transcriptional e
71 evealed that the cGAS mRNA has high ribosome occupancy at exon 1 and codon-specific pauses at positio
73 lactam ampicillin to predict target molecule occupancy at MIC from antimicrobial action with 90% accu
76 ctive enhancers while the induction of NIPLB occupancy at promoters is primarily associated with GC-r
80 ent with a model in which incomplete agonist occupancy at the four receptor subunits can provide acti
82 ith these Y138 mutant genomes even though E2 occupancy at the viral origin was equivalent to that of
86 e genes, and identify differences in PfAP2-G occupancy between gametocytes derived via next-cycle and
87 e against short-circuiting using an electron occupancy blockade effect, without relying on nuanced ch
89 e binds at the KOR site and suggest that KOR occupancy by naltrexone may be related to clinical respo
91 cupancy plot was applied to compute receptor occupancy by scopolamine and nondisplaceable distributio
92 ion, DNA methylation, chromatin looping, and occupancy by transcription factors and RNA-binding prote
95 pancy and [(11)C]CUMI101 to measure 5-HT(1A) occupancy; Cohort 2 received [(11)C]MDL100907 for 5-HT(2
96 5-HT(2A) occupancy and [(11)C]DASB for SERT occupancy; Cohort 3 underwent scanning with [(11)C]-(+)-
99 ative analyses of RNA splicing and chromatin occupancy, combined with chromatin tethering assays, dem
100 cryo-EM can detect subtle changes in glycan occupancy, composition, and dynamics that impact glycan
102 sites occupied by CHD7, and decreased RUNX1 occupancy correlated with loss of CHD7 localization.
103 muli elicit specific changes in CKM promoter occupancy correlating to altered transcriptional outputs
105 nscriptome profiles and transcription factor occupancy data are used to annotate regulatory factors,
107 res Novas, Portugal), with evidence of human occupancy dating to ca. 400 ka (Marine Isotope Stage 11)
108 ve CO(2) sensing techniques can predict room occupancy detection based on CO(2) levels exhaled by hum
111 Third, emergent modalities that convert occupancy-driven mode of action SMIRNAs into event-drive
115 es in thermal tolerances strongly influenced occupancy dynamics such that species that are less cold-
117 le energy transfer probes to quantify target occupancy for all 21 human CDKs in live cells, and prese
118 ctive site loops corresponds to an increased occupancy for bound GDP, suggesting an induced-fit foldi
119 L-seq identifies distinct patterns of genome occupancy for different classes of transcripts as well a
121 are largely confined to low and intermediate occupancy genes; high occupancy genes are unchanged.
123 gregated data layers for body shape, habitat occupancy, geographic distribution, and paleontological
124 the genome, several events with altered CTCF occupancy have been reported as associated with effects
125 net networks, suggesting that the "U-shaped" occupancy histogram and its implications for network hea
126 warming riverscape, we described changes in occupancy (i.e., site extirpation and colonization proba
127 f nodule coinfection by rhizobia, with mixed occupancy identified in ~20% of nodules, containing up t
128 equal area but different shape lead to equal occupancy if shapes are isotropic (e.g., squared or circ
131 t support quantitative assessments of target occupancy in cultured cells, emphasizing generalizable m
133 8 associates with regions of high nucleosome occupancy in multiple chromatin states, including histon
134 , Ru(1+/2+) ) yields materials with partial occupancy in Ni/Ru 3d/4dx2-y2 -H 1s bands which are anal
136 es in chromatin accessibility and nucleosome occupancy in primary cells during lymphoid development,
137 ressant activity and dose-dependent receptor occupancy in rats support its potential therapeutic util
138 regulate histone acetylation and nucleosome occupancy in the beta-globin locus control region and ga
139 statistics and suggest reducing the digital occupancy in the case of multiple targets in the same di
140 y, exhibit constitutively high psbA ribosome occupancy in the dark and differ in this way from mutant
142 odes in the inner and outer k-shells and low occupancy in the middle shells of financial and ecologic
143 profile accessible chromatin and nucleosome occupancy in these largely undifferentiated tissues and
144 ne with a sequence that increases nucleosome occupancy in vivo reduced readthrough transcription and
145 atin accessibility, and transcription factor occupancy in wild-type or DNA methylation-deficient mous
146 Following peroxide stress, cyclin C promoter occupancy increased for genes it activates while decreas
147 nscript sequencing studies reveal that Pol I occupancy increases as downstream AT content increases a
148 n induced a new pattern of cyclin C promoter occupancy indicating that this control is fine-tuned to
149 es in the chromatin state such as nucleosome occupancy influence the cold-induced AS remains poorly u
153 results show that characteristic nucleosome occupancy levels are strongly associated with the type a
160 case study is developed for a neural dynamic occupancy model of North American bird populations, trai
162 ting in Project FeederWatch to build dynamic occupancy models for 14 species of wintering birds.
165 rge cooperativity C and small effective bath occupancy n(b), resulting in a quantum cooperativity C(e
166 ), 5-HT(2A) and serotonin transporter (SERT) occupancies of brexpiprazole in adult subjects with schi
167 e frequently accompanied by reduced promoter occupancies of TBP, and diminished transcription; and In
168 phosphorylated fraction P(m) showed overall occupancies of ~8 P(i) (+/- 5) with a bell-shaped distri
172 equences are best explained by the predicted occupancy of binding sites, regardless of binding site i
173 rangement uncovered genome-wide chromatin co-occupancy of Brd4 and H3K27Ac and robust enrichment of H
174 t dotterel declines-in both density and site occupancy of breeding males-primarily occurred on low an
176 BK1 levels), and the expression and ribosome occupancy of cGAS-dependent inflammatory genes (Ccl5 and
177 matory pathways, and altered the genome-wide occupancy of critical transcription factors involved in
179 of drought, and is often associated with the occupancy of epiphytic, epilithic, semi-arid and arid en
184 DNA damage, which then resulted in enhanced occupancy of NF-kB, P-TEFb, and serine 2 phosphorylated
187 ith previous studies, we find that chromatin occupancy of PRC2 increases drastically when it is force
188 molecules to bind, similar to small molecule occupancy of protein binding pockets, thus creating the
190 uces transcription initiation by diminishing occupancy of sequence-specific regulatory elements.
191 ver disease (NAFLD) patients and obese mice, occupancy of SHP and DNMT3A and DNA methylation at lipog
192 n addition, 3D-SMART is able to quantify the occupancy of single Spinach2 RNA aptamers and capture ac
193 of sites, but that in the genome the overall occupancy of TFs is the primary determinant of activity.
195 mplications for the mechanisms governing tSC occupancy of the adult NMJ and for conditions that adver
197 es as part of a clinical study assessing the occupancy of the dual GCGR/glucagon like peptide-1 recep
198 hat under conditions of increased chromosome occupancy of the Escherichia coli SMC complex, MukBEF, t
202 the interaction determinants and reveals the occupancy of the receptor major subpocket by the CXCL12
203 combination of low TFIIH occupancy and high occupancy of the transcription elongation factor Spt4/Sp
204 ely independent of Rad26, likely due to high occupancy of the transcription initiation/repair factor
205 l opening is also associated with changes in occupancy of the transmembrane domain lipid binding site
209 n is explained by the requirement of correct occupancy of these metal-binding sites coupled to a slow
210 ther methods to test the association between occupancy of tropical habitats and speciation rates.
212 Cut and Run analysis revealed the direct occupancy of USF2 at HOXA9 promoter in MLLr leukemia cel
219 lication is required to maintain full Pol II occupancy on viral DNA and to promote elongation on late
223 unique applications, such as recording of TF occupancy over time and cell type specificity through co
224 kage is influenced by vesicle size and cargo occupancy: overexpressing an inert cargo protein or redu
227 ines occupancy, and the relationship between occupancy, pathway inhibition and clinical outcomes rema
230 stically significant differences in ribosome occupancy patterns for model organisms ranging from yeas
232 nuclear targeted Akt Substrate-based Tandem Occupancy Peptide Sponge (Akt-STOPS) that we developed f
236 sites with different areas, we find that the occupancy probability ratio is directly proportional to
238 ing chromatin immune precipitation-seq-based occupancy profiles of H3K4me3 and H3Kme1 at Satb1 gene l
240 nitoring RNA translation; ranging from codon occupancy profiling, identification of actively translat
242 elding a "U-shape" in a histogram of k-shell occupancy) provide resilience against both local targete
243 ing cells with good agreement to single-cell occupancies quantified via microscopy, establishing robu
245 peration at a hospital with an above average occupancy rate (n = 20,865, 61.6%), whereas only a small
247 as a monotonic relationship between hospital occupancy rate and the odds of experiencing a complicati
249 On multivariable analysis, low hospital occupancy rate was associated with increased odds of a c
251 ents operated on at hospitals that had a low occupancy rate were at markedly higher risk of complicat
252 ized a novel hospital quality metric coined "occupancy rate" based on publicly available data to asse
254 endency was observed at D(2) receptors, with occupancies reaching 64 +/- 8% (mean +/- SD) following 1
256 ical K8.1 late gene promoter, their promoter occupancy requires the presence of the other vTAs, sugge
259 of the joint probability distribution of the occupancy spectrum; computation is much faster than real
263 bution, metabolite experiments, and receptor occupancy studies using CP-101,606, an established GluN2
264 s) and Virginia rails (Rallus limicola) from occupancy surveys conducted during and between breeding
265 stablish a generalizable definition for high occupancy target (HOT) loci and identify putative driver
268 ously identified a preferred position of PAX occupancy that accounts for all previously described fea
269 at AML displays an aberrant increase in CTCF occupancy that targets key genes for AML development and
270 correlation between SD strength and ribosome occupancy that was previously masked by other contributi
271 e was carried out to evaluate the fractional occupancy theta of the accessible space for almost 40 00
273 nct aromatic amino acids jointly communicate occupancy to the active site via subtle changes in dynam
274 otonal faunas might experience high rates of occupancy turnover, in a process parallel to that alread
278 collecting fMRI data, called vascular space occupancy (VASO) [4, 5], to measure neural activations a
280 However, quantitative analysis of promoter occupancy versus expression level has suggested that unk
281 5-AzadC-induced DNA damage enhanced P-TEFb occupancy via a mechanism that involved activation of AT
286 d coordinates of 150 macrocycles resulted in occupancy-weighted conformational ensembles that exhibit
287 on nonmacrocycles, de novo fitting produced occupancy-weighted ensembles of many conformers that wer
289 ber, size, shape, position within cells, and occupancy, which report on activity of lysosome-driven p
291 .0% (95% CI = 42.0%-54.0%) reduction in site occupancy with declines common in warmer stream reaches
292 where SF sites display a uniform decrease in occupancy with K(+) concentration, in the low millimolar
293 with HOXB1, HOXA1 shows an enrichment in co-occupancy with PBX proteins on target sites and exists i
294 rout species exhibited small changes in site occupancy, with bull trout experiencing a 9.2% (95% CI =
295 altrexone was negatively associated with KOR occupancy, with significant effects of FH status (t(1,43
298 rganic structure-directing agents (SDAs) for occupancy within microporous voids of chabazite (CHA) ze
300 A logistic regression model including KOR occupancy, YOD, and FH variables achieved an 84% predict