ライフサイエンスコーパス: oesophagus

1 and immune activation occurs locally, in the oesophagus.

2 ar smooth-muscle fibres within the abdominal oesophagus.

3 ween atopy and malignancy the lung, skin and oesophagus.

4 transport it back to the throat and into the oesophagus.

5 ed by approximately 70% compared with normal oesophagus.

6 in the perception of pain originating in the oesophagus.

7 risk of neoplastic progression in Barrett's oesophagus.

8 g results in improved detection of Barrett's oesophagus.

9 orded pressures in the hypopharynx and upper oesophagus.

10 stinal metaplasia and dysplasia in Barrett's oesophagus.

11 othelial growth factors (VEGFs) in Barrett's oesophagus.

12 ces and transports the particles towards the oesophagus.

13 of particle transport from the rakers to the oesophagus.

14 might prevent the precursor lesion Barrett's oesophagus.

15 a pectoris but generally originates from the oesophagus.

16 Acid was infused into the lower oesophagus.

17 eral cortical projections to the pharynx and oesophagus.

18 which receive vagal afferent input from the oesophagus.

19 afferent feedback from the face, pharynx and oesophagus.

20 visit, and 50.7% were never biopsied in the oesophagus.

21 - a donut-shaped brain organised around the oesophagus.

22 is and monitoring of patients with Barrett's Oesophagus.

23 n of cancers of the oral cavity, pharynx and oesophagus.

24 esophageal adenocarcinoma (EAC) or Barrett's oesophagus.

25 TFF3) is a non-endoscopic test for Barrett's oesophagus.

26 eventing reflux of gastric contents into the oesophagus.

27 ion of EoE is spontaneous perforation of the oesophagus.

28 sure zone that prevents acid reflux into the oesophagus.

29 ng behaviours were present within the distal oesophagus.

30 actors to prioritise endoscopy for Barrett's oesophagus.

31 t occurs during the development of Barrett's oesophagus.

32 n for multi-layered epithelium and Barrett's oesophagus.

33 ndoscopic therapies for dysplastic Barrett's oesophagus.

34 and overtreatment in patients with Barrett's oesophagus.

35 ated and reliable in patients with Barrett's oesophagus.

36 in the lung, four in the skin and one in the oesophagus.

37 that are specific to patients with Barrett's oesophagus.

38 tructural and functional regeneration of the oesophagus.

39 n whose expression is highly enriched in the oesophagus.

40 risk factor for the development of Barrett's oesophagus.

41 mas (9; pancreatic (3), small-cell lung (4), oesophagus (1), endometrium (1)), adenocarcinomas (6; lu

42 ttributable cancer cases, and cancers of the oesophagus (189 700 cases [110 900-274 600]), liver (154

43 3 (TFF3), can be used to diagnose Barrett's oesophagus, a precursor condition to oesophageal adenoca

44 d precursor lesions in people with Barrett's oesophagus--a metaplastic disorder that confers a high r

45 ual care group were diagnosed with Barrett's oesophagus (absolute difference 18.3 per 1000 person-yea

46 Aging normal human oesophagus accumulates TP53 mutant clones.

47 c, histologically confirmed carcinoma of the oesophagus (adenocarcinoma, squamous-cell, or undifferen

48 Surveillance of Barrett's oesophagus allows us to study the evolutionary dynamics

49 ample comprised 6167 patients with Barrett's oesophagus and 4112 individuals with oesophageal adenoca

50 up-regulated in the progression of Barrett's oesophagus and beta-catenin mediated transcription of c-

51 he lower oesophageal sphincter (LES), distal oesophagus and crural diaphragm.

52 nfined to people with adenocarcinomas of the oesophagus and gastro-oesophageal junction (Siewert type

53 ort consisted of 468 patients with Barrett's oesophagus and intestinal metaplasia.

54 emerging chronic inflammatory disease of the oesophagus and is clinically characterized by upper gast

55 s necessary for the development of Barrett's oesophagus and its progression to cancer, and new stride

56 from dysfunction at the mouth, pharynx, and oesophagus and may predispose individuals to aspiration

57 e T-helper 1 response in normal and inflamed oesophagus and normal intestine.

58 his situation is exacerbated both in Barrett oesophagus and OAC by a historical clinical reliance on

59 of research on the heterogeneity of Barrett oesophagus and OAC, summarizing our knowledge of the fac

60 the number of known risk loci for Barrett's oesophagus and oesophageal adenocarcinoma and revealed n

61 genome-wide association studies of Barrett's oesophagus and oesophageal adenocarcinoma available in P

62 progression of healthy epithelial, Barrett's oesophagus and oesophageal adenocarcinoma cell lines.

63 tium investigating the genetics of Barrett's oesophagus and oesophageal adenocarcinoma, we aimed to i

64 ey molecules in the development of Barrett's oesophagus and oesophageal adenocarcinoma, which might e

65 sk variants for the development of Barrett's oesophagus and oesophageal adenocarcinoma.

66 ress the devices during delivery through the oesophagus and other narrow orifices in the digestive sy

67 r somatic mutant clones in ostensibly normal oesophagus and skin.

68 easured with balloon catheters placed in the oesophagus and stomach.

69 types of surgery used to treat cancer of the oesophagus and summarise the available data about their

70 ting rhythmic, phasic activity in the distal oesophagus and that Ca(2+) release occurs in ICC-IM via

71 cinomas (SqCCs) of the lungs, head and neck, oesophagus, and cervix account for up to 30% of cancer d

72 nt of non-melanoma skin cancer and Barrett's oesophagus, and improved photosensitising drugs are in d

73 enetic variations from MFD-1, tumour, normal oesophagus, and leucocytes were analysed with SNP6.

74 cancers of the oral cavity, pharynx, larynx, oesophagus, and liver, and causes a small increase in th

75 of several complex tissues such as trachea, oesophagus, and skeletal muscle in animal models and hum

76 osed lower oesophagus, the non-exposed upper oesophagus, and the cutaneous area of pain referral, bef

77 ce) suggests immune activation occurs in the oesophagus, and the relative lack of langerhans cells (C

78 orts to screen patients at risk of Barrett's oesophagus, and whether such efforts avert cancer death.

79 al nociceptive-like fibres in the guinea-pig oesophagus are derived from two embryonically distinct s

80 structures such as the respiratory tract and oesophagus are diverse, comprising several subtypes of f

81 The metaplastic cells of Barrett's oesophagus are predisposed to develop these cancer hallm

82 ium (believed to be a precursor of Barrett's oesophagus) are both characterized by the expansion of t

83 a (OAC) and its precursor condition, Barrett oesophagus, are characterized by phenotypic and molecula

84 ns has been demonstrated in the human distal oesophagus as well as in the dog proximal LES but is abs

85 case-control pairs of the head and neck and oesophagus, as well as 443 additional controls.

86 Half of all leiomyoma patients have oesophagus-associated complaints, such as dysphagia and

87 equency of ecDNA increased between Barrett's-oesophagus-associated early-stage (24%) and late-stage (

88 imary outcome was the diagnosis of Barrett's oesophagus at 12 months after enrolment, expressed as a

89 Barrett oesophagus (BE) is a premalignant condition which predis

90 (EAC) and the pre-invasive tissue, Barrett's oesophagus (BE), provide an ideal example in which to ob

91 Barrett oesophagus (BE), the only known histological precursor o

92 sifying different mucosal types in Barrett's oesophagus (BE)-a precursor of EC.

93 e is recommended for patients with Barrett's oesophagus because, although the progression risk is low

94 Barrett's oesophagus (BO) is the only known precancerous precursor

95 In Barrett's oesophagus (BO), the precursor of oesophageal adenocarci

96 lance is the clinical standard for Barrett's oesophagus, but its effectiveness is inconsistent.

97 hanges that have been described in Barrett's oesophagus can be categorised according to the predomina

98 High-grade dysplasia in columnar-lined oesophagus can be eradicated by endoscopic photodynamic

99 ally invasive abdominal technique, the lower oesophagus can be mobilised to the mediastinum without p

100 The precancerous lesion known as Barrett's oesophagus can evolve to oesophageal adenocarcinoma in d

101 ctive data on head and neck cancer (HNC) and oesophagus cancer are limited.

102 samples and evaluated in relation to HNC and oesophagus cancer risk and post-diagnosis all-cause mort

103 Achalasia is a rare motility disorder of the oesophagus characterised by loss of enteric neurons lead

104 Obesity increases the risk of cancers in the oesophagus, colorectum, breast, endometrium, and kidney.

105 uctions in HRQoL scores related to Barrett's oesophagus compared with controls from the general popul

106 ux would increase the detection of Barrett's oesophagus compared with standard management.

107 The vagal nociceptive-like fibres in the oesophagus comprise two distinct subtypes dictated by th

108 fficacy of a dedicated service for Barrett's oesophagus, cost-effectiveness and appropriateness of cu

109 inoma (OAC) or its precursor state Barrett's oesophagus coupled with open chromatin maps to identify

110 However, only a few patients with Barrett's oesophagus develop adenocarcinoma, which complicates cli

111 6 x 10(-8)) and was independent of Barrett's oesophagus development (p=0.45).

112 ast 18 years with a non-dysplastic Barrett's oesophagus diagnosis at their last endoscopy who were un

113 ation in the lung (asthma), skin (eczema) or oesophagus (eosinophilic oesophagitis; EoE) and cancer a

114 generates tone, whereas the adjacent distal oesophagus exhibits phasic contractions.

115 age, in the breast, colorectum, endometrium, oesophagus, extrahepatic bile duct, gallbladder, head an

116 essed in all tissues examined, including the oesophagus, eye, liver, intestine, posterior and anterio

117 infusion, their pain threshold in the upper oesophagus fell further and for longer (mean fall in are

118 idy in a cohort of 350 people with Barrett's oesophagus followed for 20,770 person-months.

119 Patients with non-dysplastic Barrett's oesophagus had a capsule-sponge test which was assessed

120 electrical stimuli applied to the pharynx or oesophagus had no effect on the response to cortical sti

121 y of squamous cell and adenocarcinoma of the oesophagus has diverged over the past several decades, w

122 pic treatment of early neoplastic lesions in oesophagus has evolved as a valid and less invasive alte

123 ffuse oesophageal spasm and hypercontracting oesophagus, have no well defined pathology and could rep

124 in microbial communities occur in the lower oesophagus in Barrett's carcinogenesis, which can be det

125 in microbial communities occur in the lower oesophagus in Barrett's carcinogenesis, which can be det

126 oscopy and aiding the diagnosis of Barrett's oesophagus in clinical practice.

127 ue to assess biomechanical properties of the oesophagus in human subjects.

128 o orthotopically replace the entire cervical oesophagus in immunocompetent rats.

129 eillance could be used in low-risk Barrett's oesophagus in lieu of endoscopy.

130 and passive biomechanical properties of the oesophagus in normal healthy humans.

131 the surveillance of patients with Barrett's oesophagus in specialist care.

132 lusive: no model completely mimics Barrett's oesophagus in terms of the presence of intestinal goblet

133 s and extracellular matrix to regenerate the oesophagus in vivo in a human being to re-establish swal

134 n mice causes hyperplasia selectively in the oesophagus, in association with increased cell prolifera

135 the major cell and tissue components of the oesophagus including functional epithelium, muscle fibre

136 In the case of Barrett's oesophagus, intestinal metaplasia occurs at the gastro-o

137 Barrett's oesophagus is a chronic precancerous condition that pred

138 Barrett's oesophagus is a metaplastic change of the lining of the

139 Barrett's oesophagus is characterised by replacement of reflux-dam

140 Hypocontracting oesophagus is generally caused by weak musculature commo

141 f homeostasis in the epithelium of the mouse oesophagus is guided by the progressive build-up of mech

142 The human oesophagus is home to a complex microbial community, the

143 tro-oesophageal reflux disease and Barrett's oesophagus is increasing.

144 The mouse embryonic oesophagus is initially lined with a simple columnar epi

145 tion in which the squamous epithelium of the oesophagus is replaced by columnar epithelium as an adap

146 Barrett's oesophagus is the main pre-cancerous condition to adenoc

147 Barrett's oesophagus is the main precursor to oesophageal adenocar

148 Barrett's oesophagus is the premalignant precursor of oesophageal

149 he optimal diagnostic strategy for Barrett's oesophagus is unclear.

150 pheral arterial disease, epilepsy, Barrett's oesophagus, ischaemic stroke, unstable angina and asthma

151 ry-level HDI for cancers of the oral cavity, oesophagus, liver, thyroid, and for Hodgkin lymphoma.

152 thy volunteers, acid infusion into the lower oesophagus lowered the pain threshold in the upper oesop

153 2.78, 95% CI 2.69-2.87), but cancers of the oesophagus, lung, stomach, myeloma, and lymphoma were as

154 ge achalasia with a dilated, non-functioning oesophagus may require oesophagectomy or enteral feeding

155 agus lowered the pain threshold in the upper oesophagus (mean decrease 18.2% [95% CI 10.4 to 26.0]; p

156 freehand motion within an intact ex vivo pig oesophagus model.

157 en oesophageal squamous mucosa and Barrett's oesophagus mucosa.

158 nts were diagnosed with dysplastic Barrett's oesophagus (n=4) or stage I oesophago-gastric cancer (n=

159 n-dysplastic [n=24] and dysplastic Barrett's oesophagus [n=23], and oesophageal adenocarcinoma [n=19]

160 temperature can be reliably measured in the oesophagus, nasopharynx, mouth, and bladder.

161 the dysplastic epithelium in columnar-lined oesophagus occurred after light activation.

162 stologically confirmed adenocarcinoma of the oesophagus, oesophagogastric junction, or stomach that h

163 ylidene-2'-deoxyguanosine were higher in the oesophagus of Aldh2-knockout mice than in wild-type mice

164 hypothalamus, pituitary, pancreas, lungs and oesophagus of mouse embryos using in situ hybridization.

165 Moderate balloon distension of the oesophagus of the rat (14-18 mmHg) provoked a significan

166 l drinking increased ALDH2 production in the oesophagus of wild-type mice.

167 The true effect of Barrett's oesophagus on life expectancy and the efficacy of long-t

168 an endoscopy) were diagnosed with Barrett's oesophagus or cancer.

169 w risk loci associated with either Barrett's oesophagus or oesophageal adenocarcinoma, within or near

170 nts were diagnosed with dysplastic Barrett's oesophagus or stage I gastro-oesophageal junction cancer

171 lly significant higher odds of cancer of the oesophagus (OR 1.83; 95% CI 1.34-2.49; p = 1.31 x 10-4),

172 ence of complex tissues such as the trachea, oesophagus, or skeletal muscle have few therapeutic opti

173 endometrium, kidney, liver, lung, lymphoid, oesophagus, ovary, pancreas, skin, soft tissue and thyro

174 diagnostic/prognostic screening of Barrett's Oesophagus patients.

175 Barrett's oesophagus predisposes to adenocarcinoma.

176 rade dysplasia in columnar-lined (Barrett's) oesophagus presents a difficult therapeutic dilemma.

177 Treatment of dysplastic Barrett's oesophagus prevents progression to adenocarcinoma; howev

178 from 86 patients representing the Barrett's oesophagus progression sequence (normal squamous control

179 The cancer hallmarks of Barrett's oesophagus provide a framework to categorise the genetic

180 eration and functional roles of ALDH2 in the oesophagus remain elusive.

181 ive stress-strain relationships of the human oesophagus resemble those of other soft biological tissu

182 The scores of patients with Barrett's oesophagus seem to be similar to those of patients with

183 st-to-hip ratio, and length of the Barrett's oesophagus segment.

184 ing nuclear GFP into the epithelium of E15.5 oesophagus, some cells expressed both K8 and GFP.

185 emical techniques with retrogradely labelled oesophagus-specific neurones and performing extracellula

186 ary, cervix, endometrium, bladder, prostate, oesophagus, squamous cell carcinoma of the head and neck

187 , including most of those originating in the oesophagus, stomach, biliary tract and pancreas, but not

188 ant diseases, including cancers of the lung, oesophagus, stomach, breast, and kidney.

189 risk factor for cancer of the head and neck, oesophagus, stomach, cervix, and bladder.

190 00 countries and territories for 11 cancers (oesophagus, stomach, colon, rectum, anus, liver, pancrea

191 r patients diagnosed with one of 11 cancers (oesophagus, stomach, colon, rectum, anus, liver, pancrea

192 global cancer survival for 11 cancer sites (oesophagus, stomach, colon, rectum, anus, liver, pancrea

193 rway, and the UK) for seven sites of cancer (oesophagus, stomach, colon, rectum, pancreas, lung, and

194 ted with an increased risk of cancers of the oesophagus, stomach, larynx, lung, and urinary bladder.

195 agnosis for eight cancer types (oral cavity, oesophagus, stomach, larynx, lung, liver, non-Hodgkin ly

196 tably for cancers with a poor prognosis (ie, oesophagus, stomach, pancreas, and lung).

197 is a metaplastic change of the lining of the oesophagus, such that the normal squamous epithelium is

198 hese data included 206 biopsies in Barrett's oesophagus surveillance and EAC cohorts from Cambridge U

199 The Barrett's Oesophagus Surveillance Study (BOSS) was the first rando

200 BOSS (Barrett's Oesophagus Surveillance Versus Endoscopy at Need Study)

201 were monitored within the acid-exposed lower oesophagus, the non-exposed upper oesophagus, and the cu

202 alterations of RA biosynthesis in Barrett's oesophagus, the precursor lesion to oesophageal adenocar

203 prediction of the transition from Barrett's oesophagus to oesophageal adenocarcinoma.

204 inct stages of this malignancy, from Barrett Oesophagus to primary tumours and advanced metastatic di

205 distributed in the digestive tract from the oesophagus to the colon.

206 ed for the growth and differentiation of the oesophagus, trachea and lung, and suggest that mutations

207 mechanical stress experienced by the growing oesophagus triggers the emergence of a bright Kruppel-li

208 ohort study (BEST2), patients with Barrett's oesophagus underwent the Cytosponge test before their su

209 nsport of tiny concentrated particles to the oesophagus using a hydrodynamic tongue.

210 lls of non-skin origin (e.g. that of cornea, oesophagus, vagina, bladder, prostate) that express the

211 sic contractile activity in the mouse distal oesophagus was also inhibited by ANO1 and VDCC antagonis

212 stents were removed after 3.5 years and the oesophagus was assessed by endoscopy, biopsy, endoscopic

213 d early steps in the initiation of Barrett's oesophagus, we assessed the expression, location and fun

214 ordings from the isolated vagally innervated oesophagus, we show that in the guinea-pig, the vagus ne

215 ra-bag pressure and ultrasound images of the oesophagus were recorded simultaneously.

216 latency reflex responses in the pharynx and oesophagus, were used to condition the cortical response

217 in stratified epithelia, most notably in the oesophagus where the Nanog promoter is hypomethylated.

218 skeletal muscles of the larynx, pharynx and oesophagus, which are essential for swallow.

219 However, most patients with Barrett's oesophagus will not progress and endoscopic surveillance

220 the guinea-pig, the vagus nerves supply the oesophagus with a large population of nociceptive-like a

221 isorder characterized by infiltration of the oesophagus with eosinophils.

222 that the vagus nerves supply the guinea-pig oesophagus with nociceptors in addition to tension mecha

223 ntenance of the structural morphology of the oesophagus with off-the-shelf non-biological scaffold an

224 al we saw full-thickness regeneration of the oesophagus with stratified squamous epithelium, a normal

225 having endoscopic surveillance for Barrett's oesophagus (with intestinal metaplasia confirmed by TFF3