ライフサイエンスコーパス: olefin metathesis

1 ed based on macrocyclization by ring-closing olefin metathesis.

2 somers, which concurrently undergo catalytic olefin metathesis.

3 enerating adaptive cross-linked polymers via olefin metathesis.

4 the appropriate chelate for stereocontrolled olefin metathesis.

5 HC) ligands that catalyze highly Z-selective olefin metathesis.

6 Finally, the C-ring was closed using olefin metathesis.

7 resulted in a highly efficient catalyst for olefin metathesis.

8 r architectures are produced by ring-closing olefin metathesis.

9 n dimer via ruthenium-catalyzed ring-closing olefin metathesis.

10 cond catalyst (molecular or solid-phase) for olefin metathesis.

11 ivity and selectivity profiles in asymmetric olefin metathesis.

12 ation of the C-3 side-chain and ring-closing olefin metathesis.

13 one based upon olefination and a second upon olefin metathesis.

14 step by a novel ring-expansion method using olefin metathesis.

15 onserves the key features of metal-catalyzed olefin metathesis.

16 ected diene (13), which is then cyclized via olefin metathesis.

17 sential for inner-sphere cyclopropanation or olefin metathesis.

18 is a fundamental, long-standing challenge in olefin metathesis.

19 g the domino cycloetherification followed by olefin metathesis.

20 y, and to realize the outstanding promise of olefin metathesis.

21 ng-closing, ring-opening, and cross carbonyl-olefin metathesis.

22 ynthesis of tetrasubstituted alkenes through olefin metathesis.

23 and reduced W(IV) sites in the initiation of olefin metathesis.

24 e E-olefins, a previously unmet challenge in olefin metathesis.

25 the precursors of the most active sites for olefin metathesis.

26 reas that have historically been enhanced by olefin metathesis.

27 ries of novel ruthenium complexes for use in olefin metathesis.

28 cobalt(II) cations, followed by ring-closing olefin metathesis.

29 lent capture of the catenane by ring-closing olefin metathesis.

30 complex, widely regarded as inactive toward olefin metathesis.

31 ollowed by selective degradation of PB using olefin metathesis.

32 A major shortcoming in olefin metathesis, a chemical process that is central to

33 tionic complex is crucial in order to become olefin metathesis active.

34 ty to synthesize propylene or isopropylidene olefin metathesis-active complexes in the absence of fre

35 activated with excess AlCl3 to form cationic olefin metathesis-active W-complexes; however, these rea

36 ore strongly bound sites are responsible for olefin metathesis activity and are formed preferentially

37 We also evaluate the olefin metathesis activity of NHC-coordinated complexes

38 The olefin metathesis activity of silica-supported molybdenu

39 The synthesis, structure, and olefin metathesis activity of the first neutral and cati

40 the overhand knot end groups by ring-closing olefin metathesis affords a single enantiomer of the tre

41 d metabolic stability of these bonds renders olefin metathesis an exceptional methodology for the syn

42 Ag(I) carbene) that promote enantioselective olefin metathesis and allylic alkylations with scope tha

43 Olefin metathesis and cyclopropanation, major reactions

44 al was tested for gas phase and liquid phase olefin metathesis and exhibited higher catalytic activit

45 here add to the body of mechanistic work for olefin metathesis and may inform the continued design of

46 Y groups in model reactions of Ru-catalyzed olefin metathesis and Pd-catalyzed C-C cross-coupling.

47 sible-light-controlled metathesis by merging olefin metathesis and photoredox catalysis.

48 peptide coupling, nucleophilic substitution, olefin metathesis, and click reactions have been the met

49 n, the missing elementary step essential for olefin metathesis, and establishes the design parameters

50 the coupling of two complex segments via an olefin metathesis, and the subsequent conversion of a di

51 f spirocyclic structures by enantioselective olefin metathesis are also disclosed.

52 Ru-based catalysts for efficient Z-selective olefin metathesis are featured.

53 sigma-bond metathesis, olefin insertion, and olefin metathesis are in fact isolobal reactions.

54 nces of Z- and enantioselective Ru-catalyzed olefin metathesis are presented.

55 antioselective processes, C-H activation, or olefin metathesis are still rarely discussed.

56 e, we demonstrate transition-metal-catalyzed olefin metathesis as a simple, effective method for heal

57 addition, Suzuki-Miyaura cross-coupling, and olefin metathesis as key steps to assemble various unnat

58 rt-butanesulfinyl aldimine, and ring closing olefin metathesis as key steps.

59 Olefin metathesis, as a powerful metal-catalysed carbon-

60 a notable effect on broadening the scope of olefin metathesis, as the stability of methylidene compl

61 Here, we discuss the developments in olefin-metathesis-based chemical recycling technologies,

62 Herein, we report a short olefin-metathesis-based total synthesis of Delta(12)-PGJ

63 hly active catalyst systems, the isomerizing olefin metathesis becomes an efficient way to access def

64 ts have shown that it can be reactivated for olefin metathesis by protonation in solution.

65 the highly active, fast-initiating ruthenium olefin metathesis catalyst (H(2)IMes)(pyr)(2)(Cl)(2)RuCH

66 ance of the heterogeneous tungsten-oxo-based olefin metathesis catalyst (WO(3)/SiO(2)) in industry, u

67 The structure of ruthenium-based olefin metathesis catalyst 3 and model pi-complex 5 in s

68 erized to a telechelic macromonomer using an olefin metathesis catalyst and 2-hydroxyethyl acrylate.

69 ivate it as a low temperature, heterogeneous olefin metathesis catalyst and confers both high activit

70 as the implications of these dynamics toward olefin metathesis catalyst and reaction design are descr

71 nvolves the use of Grubbs' second-generation olefin metathesis catalyst for cross-metathesis of alkyl

72 The classical WO3/SiO2 olefin metathesis catalyst is combined to other catalyst

73 r agent (CTA) with a highly active ruthenium olefin metathesis catalyst resulted in the formation of

74 substrate concentration up to 25 mM using an olefin metathesis catalyst selectively immobilized insid

75 benzenethiolate ligand resulted in an active olefin metathesis catalyst with remarkable Z selectivity

76 tive tone photoresist using a photoactivated olefin metathesis catalyst, which can be quickly prepare

77 The thermal stability of selected olefin metathesis catalysts allowed elevated temperature

78 ies for the design and implementation of new olefin metathesis catalysts and substrates are discussed

79 Ruthenium-based olefin metathesis catalysts are used in laboratory-scale

80 A new family of ruthenium-based olefin metathesis catalysts bearing a series of thiazole

81 Ruthenium-based olefin metathesis catalysts bearing dithiolate ligands h

82 A series of ruthenium olefin metathesis catalysts bearing N-heterocyclic carbe

83 Ruthenium-based Hoveyda-type olefin metathesis catalysts bearing novel rigid spirocyc

84 Mo and W MonoAryloxide-Pyrrolide (MAP) olefin metathesis catalysts can couple terminal olefins

85 The synthesis of olefin metathesis catalysts containing chiral, monodenta

86 Heterogeneous olefin metathesis catalysts exhibit low active site dens

87 and the great interest in developing latent olefin metathesis catalysts for numerous applications, w

88 A library of 29 homologous Ru-based olefin metathesis catalysts has been tested for ethenoly

89 Ru- or Mo-based chiral olefin metathesis catalysts have proven to be inefficien

90 Monoaryloxide-pyrrolide (MAP) olefin metathesis catalysts of molybdenum that contain a

91 A series of ruthenium olefin metathesis catalysts of the general structure (H(

92 Olefin metathesis catalysts provide access to molecules

93 erves as a platform for the discovery of new olefin metathesis catalysts that allow for efficient com

94 the first-generation, phosphine-based Grubbs olefin metathesis catalysts to second-generation catalys

95 A series of second-generation ruthenium olefin metathesis catalysts was investigated using a com

96 oach to access a new family of Ru-alkylidene olefin metathesis catalysts with specialized properties

97 They are highly active olefin metathesis catalysts, allowing for turnover numbe

98 ethylene and tungsten-based imido alkylidene olefin metathesis catalysts, if not others.

99 Access to leading olefin metathesis catalysts, including the Grubbs, Hovey

100 st is fully compatible with state-of-the-art olefin metathesis catalysts.

101 R(3))(Cl)(2)Ru=CHR', which are highly active olefin metathesis catalysts.

102 he mechanism and activity of ruthenium-based olefin metathesis catalysts.

103 s of the active Fe(III) and Ga(III) carbonyl-olefin metathesis catalysts.

104 hanediene was unreactive toward a library of olefin metathesis catalysts.

105 to access efficient and well-defined latent olefin metathesis catalysts.

106 ve species of industrial supported MoO3/SiO2 olefin metathesis catalysts.

107 nium benzylidene complexes are well-known as olefin metathesis catalysts.

108 Olefin metathesis catalyzed by iron complexes has garner

109 scope of catalyst-controlled stereoselective olefin metathesis considerably.

110 n-chain polypseudorotaxanes via ring-opening olefin metathesis copolymerization of macrocycles and me

111 nyl-3-pentene-1,5-diyl)iron complexes toward olefin metathesis, cycloaddition, and mild oxidations (M

112 Recent examples of this approach include olefin-metathesis-derived macrocycles that employ ring c

113 d to prepare variants of previously reported olefin-metathesis-derived macrocycles.

114 cond-generation strategy, a remarkable cross olefin metathesis dimerization cascade was discovered an

115 eometrical isomer by use of silicon-tethered olefin metathesis employing the Schrock carbene [(CF3)2M

116 tional group tolerance of ruthenium-mediated olefin metathesis enables a host of new possibilities fo

117 terminal olefin, thereby enabling successive olefin metathesis events.

118 a comprehensive mechanistic understanding of olefin metathesis, exemplifying infinite opportunities f

119 mework in SALEM-14 prevents "intermolecular" olefin metathesis from occurring between the pillars in

120 Olefin metathesis has become an efficient tool in synthe

121 , no general protocol for catalytic carbonyl-olefin metathesis has been reported.

122 Olefin metathesis has emerged as a promising strategy fo

123 Lately, stereoretentive olefin metathesis has garnered much attention as a metho

124 the past eight years, the field of carbonyl-olefin metathesis has grown significantly and expanded f

125 Olefin metathesis has had a large impact on modern organ

126 Lewis acid-catalyzed carbonyl-olefin metathesis has introduced a new means for reveali

127 Olefin metathesis has recently emerged as a viable react

128 ctivated ruthenium catalysts for Z-selective olefin metathesis have been synthesized.

129 Recent studies in olefin metathesis have focused on the synthesis of catal

130 involving carbon-carbon double bonds, namely olefin metathesis, have been well established with broad

131 Ruthenium carbenes, famously used in olefin metathesis, have impacted numerous research areas

132 carbonylation, polymerization, cyclization, olefin metathesis, Heck coupling, hydroarylation Michael

133 prepared in a one-pot tandem dehydrogenation/olefin metathesis/hydrogenation sequence directly from a

134 The scope and limitations of olefin metathesis in bioconjugation, however, remain unc

135 ese currently available methods for carbonyl-olefin metathesis in complex molecule synthesis.

136 and performance opens new opportunities for olefin metathesis in complex, water-rich settings.

137 oconjugation but also for the application of olefin metathesis in general synthetic endeavors.

138 ptides but also for applying stereoselective olefin metathesis in general synthetic endeavors.

139 stable species, its concentration can impact olefin metathesis in other ways.

140 ntribute to further advancements in carbonyl-olefin metathesis in the coming years.

141 a mechanochemical approach for Ru-catalyzed olefin metathesis, including cross-metathesis and ring-c

142 Olefin metathesis is a powerful tool for the formation o

143 Olefin metathesis is a widely used catalytic process for

144 Olefin metathesis is an incredibly valuable transformati

145 The utility of H-bonding in catalytic olefin metathesis is elucidated through development of e

146 The versatility of olefin metathesis is evident from its successful applica

147 Olefin metathesis is increasingly incorporated in polyfu

148 ally controlled catalytic Z- and E-selective olefin metathesis is introduced.

149 Olefin metathesis is now one of the most efficient ways

150 This ring-expanding olefin metathesis is suggested to be a simple way to pre

151 ely on a phenomenological description of the olefin metathesis kinetics, limiting their ability to mo

152 Mechanistic studies disclose an intriguing 'olefin-metathesis-like' pathway that involves an unexpec

153 ce that iron complexes adhere to the Chauvin olefin metathesis mechanism.

154 his work, we report a novel and short Grubbs olefin metathesis-mediated synthesis of methylene and di

155 Despite notable progress, olefin metathesis methods for preparation of ( Z)-alpha,

156 neration Grubbs catalyst, the ring-expanding olefin metathesis of a monocyclooct-4-en-1-yl functional

157 rrangement were synthesized via ring-closing olefin metathesis of bis(allyoxy)methyl derivatives usin

158 Olefin metathesis of the triene substrate 12 afforded th

159 A synthesis via olefin metathesis of the unprotected heterocycle and a c

160 erstanding about the underlying mechanism in olefin metathesis of this new type of catalysts.

161 fied mechanistic framework for heterogeneous olefin metathesis, offering new strategies to enhance ac

162 n numerous significant advances in catalytic olefin metathesis (OM) during the past two decades.

163 molecules traditionally generated by olefin-olefin metathesis or olefination.

164 ctive site generation, renewal, and decay in olefin metathesis over silica-supported molybdenum oxide

165 A tandem olefin metathesis/oxidative cyclization has been develop

166 or conjugation to other molecules (e.g., by olefin metathesis, peptide ligation, etc.).

167 le, underwent an entropy-driven ring-opening olefin metathesis polymerization (ROMP) to provide a pol

168 em based on the ethylene activation of Ru-I2 olefin metathesis precatalysts.

169 The first continuous flow Z-selective olefin metathesis process is reported.

170 pment of catalyst-controlled stereoselective olefin metathesis processes has been a pivotal recent ad

171 y with which allylic alcohols participate in olefin metathesis processes will be presented as well.

172 Atroposelective ring-closing olefin metathesis proved critical for the stereospecific

173 atter compounds through Wacker oxidation and olefin metathesis provides diversely functionalized buil

174 shed in the field of chiral Ru- and Mo-based olefin metathesis, providing an asymmetric access to str

175 yl-Suzuki coupling sequence, or ring closing olefin metathesis (RCM) for the closure of the second la

176 synthesis exploits the power of ring-closing olefin metathesis (RCM) in a stereospecific way.

177 atic hydrocarbons (PAHs) by the ring-closing olefin metathesis (RCM) of pendant olefins on a phenylen

178 lkenyl amino acids and (ii) the ring-closing olefin metathesis (RCM) of the resulting resin-bound pep

179 es of these macrocycles feature ring-closing olefin metathesis (RCM) reactions catalyzed by ruthenium

180 -1' on the tricyclic core via a ring-closing olefin metathesis (RCM) strategy with the second-generat

181 Ring-closing olefin metathesis (RCM) then affords the closed-loop kno

182 kylidene 1 and undergone facile ring-closing olefin metathesis (RCM) to give 21- and 23-membered macr

183 CH2)3N]Mo(NB(C6F5)3) with PMe3, ring-closing olefin metathesis (RCM) was employed to join the aryl ri

184 ination of a highly stereoselective tethered olefin metathesis reaction and a Julia-Kocienski olefina

185 n A analogues were synthesized utilizing the olefin metathesis reaction and evaluated in a calcineuri

186 While the corresponding carbonyl-olefin metathesis reaction can also be used to construct

187 Specifically, the catalytic olefin metathesis reaction has led to profound developme

188 es can be manipulated and managed so that an olefin metathesis reaction may occur more efficiently an

189 ety of C-1-disaccharide glycals based on the olefin metathesis reaction of enol ethers and alkenes is

190 The olefin metathesis reaction of two unsaturated substrates

191 eased phosphine dissociation leads to faster olefin metathesis reaction rates, which is of direct sig

192 ct relative stereochemistry and (2) a double olefin metathesis reaction to deliver both cyclohexene r

193 e synthetic approach was the diene-ene cross olefin metathesis reaction to generate the C6-C7 olefin

194 here is no single mechanism for the Ru-based olefin metathesis reaction.

195 lecular wire can be grown in situ through an olefin metathesis reaction.

196 nd C (3) was constructed using an impressive olefin metathesis reaction.

197 s accomplished efficiently by a ring-closing olefin metathesis reaction.

198 he presence of a small-molecule alkene in an olefin metathesis reaction.

199 significant catalytic activity in promoting olefin metathesis reactions and provide products of high

200 onic units on the efficiency of Ru-catalyzed olefin metathesis reactions are discussed.

201 derivatives, promote exceptional Z-selective olefin metathesis reactions are elucidated.

202 s that control the stereochemical outcome of olefin metathesis reactions have been recently introduce

203 Catalytic carbonyl-olefin metathesis reactions have recently been developed

204 for turnover numbers up to 10,000 in various olefin metathesis reactions including alkenes bearing ni

205 nalized Ru nanoparticles were synthesized by olefin metathesis reactions of carbene-stabilized Ru nan

206 s the development of strategies for carbonyl-olefin metathesis reactions relying on stepwise, stoichi

207 eported herein efficiently promote benchmark olefin metathesis reactions such as the ring-closing of

208 and are able to participate in high-yielding olefin metathesis reactions that afford acyclic 1,2-disu

209 Ethylene is the byproduct of olefin metathesis reactions that involve one or more ter

210 the isoeugenol/crotonaldehyde combination in olefin metathesis reactions was demonstrated by a short

211 d initiation as well as overall activity for olefin metathesis reactions was examined.

212 Olefin metathesis reactions with 3E-1,3-dienes using Z-s

213 e resulting nanoparticles could also undergo olefin metathesis reactions with vinyl-terminated molecu

214 aden the current scope of catalytic carbonyl-olefin metathesis reactions.

215 ls of stereochemical control in Ru-catalyzed olefin metathesis reactions.

216 ) is among the most widely used catalysts in olefin metathesis reactions.

217 distinct from previously established olefin-olefin metathesis reactions.

218 gn principle of iron(III)-catalyzed carbonyl-olefin metathesis reactions.

219 Although initial efforts to execute an olefin metathesis rearrangement to form key carbon-carbo

220 l experiments shed light on the oxocarbenium-olefin metathesis/rearrangement process as well as on th

221 The success of enantioselective olefin metathesis relies on the design of enantioenriche

222 he application of continuous-flow methods to olefin metathesis represents one of the most promising e

223 ort the development of a facile ring-opening olefin metathesis route to alkaline anion exchange membr

224 for catalytic and thermally allowed carbonyl-olefin metathesis (see scheme).

225 ersion of olefins, heterogeneously catalysed olefin metathesis sees commercial applications in the pe

226 ition of TMSCl to FeCl(3)-catalyzed carbonyl-olefin metathesis, specifically for substrates that are

227 The olefin metathesis step can be carried out with substrate

228 The development of a catalytic carbonyl-olefin metathesis strategy is reported, in the context o

229 ides were found to be exceptionally reactive olefin metathesis substrates, enabling a broad range of

230 A novel one pot olefin metathesis-Takai olefination protocol that should

231 lded structurally well-defined catalysts for olefin metathesis that are used to synthesize an array o

232 xchange and postsynthesis modification using olefin metathesis, the noninterpenetrated SALEM-14 was f

233 Ring-closing olefin metathesis then completes the knots.

234 atalysts have been shown to promote carbonyl-olefin metathesis through a critical four-membered-ring

235 Catalytic olefin metathesis--through which pairs of C = C bonds ar

236 catalyst initiation, a major design goal in olefin metathesis, thus has the negative consequence of

237 kbone using ruthenium-catalyzed ring-closing olefin metathesis to afford a molecular charm bracelet s

238 n quaternary stereocenter and a ring-closing olefin metathesis to concomitantly form the spirocyclic

239 The other key steps involved ring-closing olefin metathesis to construct both dihydropyran units,

240 es (1) a remarkably E-selective ring-closing olefin metathesis to construct the 12-membered benzolact

241 ing monomers, followed by ruthenium-mediated olefin metathesis to effect closure of the seven-membere

242 gand strands can be cyclized by ring-closing olefin metathesis to form a molecular trefoil knot in 58

243 lexes is covalently captured by ring-closing olefin metathesis to form topologically chiral molecular

244 only for expanding the scope of Z-selective olefin metathesis to peptides but also for applying ster

245 ment of new materials and the application of olefin metathesis to the recycling of commercial materia

246 ropenyl syringol enriched oil followed by an olefin metathesis to yield bisphenols and butene-2, thus

247 bilization chemistries, such as ring-closing olefin metathesis, to stabilize loop, turn, and alpha-he

248 These olefin metathesis transformations proceed efficiently an

249 @SiO(2-700) was shown to be highly active in olefin metathesis upon removal of pyridine ligands throu

250 alities so that MOPs can be cross-linked via olefin metathesis using Grubbs second generation catalys

251 oselective epoxide opening, and ring-closing olefin metathesis using Grubbs' catalyst as the key step

252 , was synthesized from a diene precursor via olefin metathesis using Grubbs's catalyst.

253 Advancements in stereoretentive olefin metathesis using tungsten, ruthenium, and molybde

254 and through applications in stereoselective olefin metathesis where Z-alkene substrates are required

255 eded a complete mechanistic understanding of olefin metathesis, which hampers further optimization of

256 eta-H elimination) occurs on Ti, followed by olefin metathesis, which occurs on W.

257 or new developments in the field of carbonyl-olefin metathesis, which traditionally relied on stoichi

258 Nonetheless, the full potential of olefin metathesis will be realized only when additional

259 he mechanism and origins of Z-selectivity in olefin metathesis with chelated Ru catalysts were explor

260 -(benzyloxy)-3-buten-2-ol and a ring-closing olefin metathesis with Grubbs' catalyst.

261 cellent catalytic performances in asymmetric olefin metathesis with high enantioselectivities (up to

262 The approach combines rapid olefin metathesis with rate-limiting isomerization.

263 nsive computational study of stereoretentive olefin metathesis with Ru-dithiolate catalysts has been

264 However, while the mechanism of olefin metathesis with ruthenium benzylidenes has been w

265 tion properties in both liquid and gas-phase olefin metathesis with the SOMC-derived catalyst outperf

266 In this regard, olefin metathesis, with its versatility and ease of oper

267 loping well-defined iron-based catalysts for olefin metathesis would be a breakthrough achievement in