ライフサイエンスコーパス: oligodendrocyte precursor cell

1 ransformation following differentiation into oligodendrocyte precursor cells.

2 ls in the postnatal SVZ but are likely to be oligodendrocyte precursor cells.

3 proliferation and inhibits the migration of oligodendrocyte precursor cells.

4 eptor thus serves as a phenotypic marker for oligodendrocyte precursor cells.

5 e they likely exert their influence on early oligodendrocyte precursor cells.

6 Similar results were obtained with oligodendrocyte precursor cells.

7 ing oligodendrocytes that differentiate from oligodendrocyte precursor cells.

8 NA levels of Ng2, a gene required to produce oligodendrocyte precursor cells.

9 cific cell types, including Pons neurons and oligodendrocyte precursor cells.

10 mature into distinct pre-astrocytes and pre-oligodendrocyte precursor cells.

11 astrocytes, microglia, oligodendrocytes, and oligodendrocyte precursor cells.

12 y neurons as well as in oligodendrocytes and oligodendrocyte precursor cells.

13 , and decline of mature oligodendrocytes and oligodendrocyte precursor cells.

14 1 was significantly decreased in spinal cord oligodendrocyte precursor cells after onset of EAE, and

15 s system remyelination is mainly mediated by oligodendrocyte precursor cells, although subventricular

16 administration of clemastine also normalized oligodendrocyte precursor cell and oligodendrocyte densi

17 g Sob-AM2, was also effective at normalizing oligodendrocyte precursor cell and oligodendrocyte densi

18 r the local production of GABAergic neurons, oligodendrocyte precursor cells and astrocytes.

19 tured the resulting cellular responses in WM oligodendrocyte precursor cells and GABAergic interneuro

20 reduced remyelination, and increased loss of oligodendrocyte precursor cells and mature oligodendrocy

21 n vitro, clemastine treatment reduced excess oligodendrocyte precursor cells and normalized oligodend

22 ances in our understanding of the biology of oligodendrocyte precursor cells and of the stage-depende

23 with RNA-seq identifies SRF-target genes in oligodendrocyte precursor cells and oligodendrocytes tha

24 mbination with MCSF, increased the number of oligodendrocyte precursor cells and promoted remyelinati

25 In vitro and in vivo experiments in oligodendrocyte precursor cells and zebrafish were perfo

26 elations between astrocyte, oligodendrocyte, oligodendrocyte precursor cell, and vascular leptomening

27 matter, apoptosis and arrested maturation of oligodendrocyte precursor cells, and hypomyelination.

28 ess select features of GABAergic neurons and oligodendrocyte precursor cells, and include both tumor

29 ally infected neural stem cells, astrocytes, oligodendrocyte precursor cells, and microglia, whereas

30 sion across species compared with neurons or oligodendrocyte precursor cells, and neuronal expression

31 ol cells, including normal human astrocytes, oligodendrocyte precursor cells, and primary explant cul

32 resses inflammation, attenuates apoptosis of oligodendrocyte precursor cells, and promotes myelinatio

33 ory neurons, and a remyelination response by oligodendrocyte precursor cells; and a later phase with

34 NG2 cells in the SVZ and RMS expressed the oligodendrocyte precursor cell antigen platelet-derived

35 Adult oligodendrocyte precursor cells (aOPCs), transformed fro

36 Unlike oligodendrocyte precursor cells, APCs do not differentia

37 ation vulnerable to PVWMI and P5 when rodent oligodendrocyte precursor cells are more vulnerable to e

38 Oligodendrocyte precursor cells are the primary source o

39 al targets and cellular process expansion by oligodendrocyte precursor cells as well as expression an

40 s indicated 4-AP stabilization of myelin and oligodendrocyte precursor cells associated with increase

41 her obvious impairment in the recruitment of oligodendrocyte precursor cells, astrocytes, or reactive

42 domains VI and V of netrin-1 repel migrating oligodendrocyte precursor cells, but lack the chemoattra

43 We show that TNFR2 drives differentiation of oligodendrocyte precursor cells, but not proliferation o

44 termine a window of opportunity during which oligodendrocyte precursor cells can successfully differe

45 nes, chemokines and growth factors, act upon oligodendrocyte precursor cells, causing their activatio

46 nic neuroinflammatory lesions, we found that oligodendrocyte precursor cells clustered perivascularly

47 cultures by co-culturing with astrocytes and oligodendrocyte precursor cells (complex culture).

48 pression of the helix-loop-helix gene Id4 in oligodendrocyte precursor cells decreases in vivo and in

49 hin the nervous system, including defects in oligodendrocyte precursor cell development and a partial

50 Oligodendrocyte precursor cells differentiate into matur

51 We explored oligodendrocyte precursor cell differentiation and myeli

52 found that p38gammaMAPK ablation accelerated oligodendrocyte precursor cell differentiation and myeli

53 -gamma is a positive regulator of endogenous oligodendrocyte precursor cell differentiation and remye

54 y, we identified novel molecules involved in oligodendrocyte precursor cell differentiation and valid

55 Thus, abortive oligodendrocyte precursor cell differentiation by fibrin

56 Specifically, exogenous CCL19 abolished oligodendrocyte precursor cell differentiation observed

57 ligodendrogenesis, it subsequently increases oligodendrocyte precursor cell differentiation, oligoden

58 le environment for or actively contribute to oligodendrocyte precursor cell differentiation, remyelin

59 We also show that oligodendrocyte precursor cells display sensitivity to t

60 -1, a secreted protein that repels migrating oligodendrocyte precursor cells during neural developmen

61 In mice that lacked RXR-gamma, adult oligodendrocyte precursor cells efficiently repopulated

62 of origin for glioma, neural stem cells and oligodendrocyte precursor cells, exhibited a high glioma

63 Motor neuron and oligodendrocyte precursor cells express Olig genes, whic

64 Further study of isolated oligodendrocyte precursor cells from SCA3 mice establish

65 an enrichment of proliferative pathways and oligodendrocyte precursor cell gene expression profile i

66 hibiting myelination by deletion of Olig2 in oligodendrocyte precursor cells impairs spatial memory i

67 luding radial glial cells in ependymomas and oligodendrocyte precursor cells in astrocytomas.

68 The alpha1B-AR is also expressed in NG2 oligodendrocyte precursor cells in both neonatal cell cu

69 Gold nanocrystal treatment of oligodendrocyte precursor cells in culture resulted in o

70 ) and retinoic acid (RA) induce purified rat oligodendrocyte precursor cells in culture to stop divis

71 nterestingly, despite a normal production of oligodendrocyte precursor cells in the double mutants, o

72 ast to multiple observations indicating that oligodendrocyte precursor cells in the embryonic day 14

73 ne fumarate can stimulate differentiation of oligodendrocyte precursor cells in vitro, in animal mode

74 usly differentiating OLs generated from pure oligodendrocyte precursor cells in vitro.

75 y lethality, effects on myelination, loss of oligodendrocyte precursor cells, increased apoptosis in

76 changed the GABA-response characteristics in oligodendrocyte precursor cells, indicating their partic

77 changed the GABA-response characteristics in oligodendrocyte precursor cells, indicating their partic

78 During development, oligodendrocyte precursor cells integrate environmental

79 cyte-derived TIMP-1 drove differentiation of oligodendrocyte precursor cells into mature oligodendroc

80 this compound induces the differentiation of oligodendrocyte precursor cells into mature oligodendroc

81 factors that inhibit the differentiation of oligodendrocyte precursor cells into myelinating oligode

82 2.2 is sufficient to convert HDFs to induced oligodendrocyte precursor cells (iOPCs).

83 Moreover, proliferation of oligodendrocyte precursor cells is altered by mutant hun

84 An intracellular timer in oligodendrocyte precursor cells is thought to help contr

85 udies demonstrated that the proliferation of oligodendrocyte precursor cells isolated from the develo

86 regulated expression of GPR17 in Oli-neu, an oligodendrocyte precursor cell line, making these cells

87 We have identified an oligodendrocyte precursor cell line, termed G144, that s

88 emastine, an antihistamine shown to increase oligodendrocyte precursor cell maturation and central ne

89 gammaMAPK was significantly downregulated as oligodendrocyte precursor cells matured into oligodendro

90 Oligodendrocyte precursor cells may differentiate into a

91 In contrast to oligodendrocyte precursor cells, microglia formed only w

92 velopment, may also be active in controlling oligodendrocyte precursor cell migration in MS, and henc

93 d modulate every aspect of myelination, from oligodendrocyte precursor cell migration to oligodendroc

94 ple sclerosis lesions are thought to inhibit oligodendrocyte precursor cell migration, limiting their

95 entative populations of neurons, astrocytes, oligodendrocyte precursor cells, newly formed oligodendr

96 NG2-expressing oligodendrocyte precursor cells (NG2 cells) are exposed

97 Synaptic signaling to NG2-expressing oligodendrocyte precursor cells (NG2 cells) could be key

98 Oligodendrocyte precursor cells (NG2 glia) are uniformly

99 promotes myelination and differentiation of oligodendrocyte precursor cells (NG2(+) cells) in a deco

100 adult CNS contains an abundant population of oligodendrocyte precursor cells (NG2(+) cells) that gene

101 bipotential oligodendrocyte-type-2 astrocyte/oligodendrocyte precursor cells (O-2A/OPCs).

102 Seeding of oligodendrocyte precursor cells on these axons results i

103 The oligodendrocyte precursor cell (OPC) arises from the sub

104 the proliferation and differentiation of the oligodendrocyte precursor cell (OPC) as well as the spat

105 Temple and Raff previously showed that an oligodendrocyte precursor cell (OPC) can divide a maximu

106 ceptor induced excitotoxicity contributes to oligodendrocyte precursor cell (OPC) damage and hypomyel

107 rphin release, we observe increased striatal oligodendrocyte precursor cell (OPC) differentiation and

108 M), bazedoxifene (BZA), as a potent agent of oligodendrocyte precursor cell (OPC) differentiation and

109 functional states of Wnt activity determine oligodendrocyte precursor cell (OPC) differentiation and

110 or GABAergic interneuron production, repress oligodendrocyte precursor cell (OPC) formation by acting

111 ons contain hyaluronan deposits that inhibit oligodendrocyte precursor cell (OPC) maturation.

112 te numbers and CNS hypomyelination, although oligodendrocyte precursor cell (OPC) numbers are normal.

113 ein (BMP) signaling, such as Noggin, promote oligodendrocyte precursor cell (OPC) production after hy

114 Gpr56-knockout mice manifest with decreased oligodendrocyte precursor cell (OPC) proliferation and d

115 ndrocyte generation by negatively regulating oligodendrocyte precursor cell (OPC) proliferation.

116 Oligodendrocyte precursor cell (OPC)-specific TrkB delet

117 l stem cells (NSC) or Pdgfra+/NG2+ committed oligodendrocyte precursor cells (OPC), two major cells o

118 ansmembrane proteoglycan NG2 is expressed by oligodendrocyte precursor cells (OPC), which migrate to

119 in reminiscent of neural stem cells (NSC) or oligodendrocyte precursor cells (OPC).

120 However, its functions for oligodendrocyte-precursor cell (OPC) differentiation wit

121 bsequent validation in both murine and human oligodendrocyte precursor cells (OPCs) and coculture sys

122 ovide an additional source of human cortical oligodendrocyte precursor cells (OPCs) and define a line

123 igration of both rat Schwann cells (SCs) and oligodendrocyte precursor cells (OPCs) and explored the

124 onal activity promotes proliferation of both oligodendrocyte precursor cells (OPCs) and gliomas, incl

125 ate that Mfsd2a is specifically expressed in oligodendrocyte precursor cells (OPCs) and is critical f

126 ek-old mice, while genes highly expressed in oligodendrocyte precursor cells (OPCs) and newly formed

127 yelin is dependent on the differentiation of oligodendrocyte precursor cells (OPCs) and oligodendrocy

128 odendrocyte lineage cells (OLCs), comprising oligodendrocyte precursor cells (OPCs) and oligodendrocy

129 type 1 to type 2 status, elevated numbers of oligodendrocyte precursor cells (OPCs) and oligodendrocy

130 In culture, purified versican-V1 inhibits oligodendrocyte precursor cells (OPCs) and promotes T he

131 d (RA) signaling promotes differentiation of oligodendrocyte precursor cells (OPCs) and remyelination

132 Oligodendrocyte precursor cells (OPCs) are a population

133 Oligodendrocyte precursor cells (OPCs) are abundant in t

134 Nerve-glia (NG2) glia or oligodendrocyte precursor cells (OPCs) are distributed t

135 sociated astrocyte-like (DAA-like) cells and oligodendrocyte precursor cells (OPCs) are enriched in t

136 Oligodendrocyte precursor cells (OPCs) are generated fro

137 Oligodendrocyte precursor cells (OPCs) are glia that giv

138 Oligodendrocyte precursor cells (OPCs) are lineage-restr

139 Oligodendrocyte precursor cells (OPCs) are non-neuronal

140 Oligodendrocyte precursor cells (OPCs) are not merely a

141 Other studies showed that oligodendrocyte precursor cells (OPCs) are responsible f

142 ventral spinal cord, motor neurons (MNs) and oligodendrocyte precursor cells (OPCs) are sequentially

143 Oligodendrocyte precursor cells (OPCs) are the major sou

144 Oligodendrocyte precursor cells (OPCs) are the only type

145 Oligodendrocyte precursor cells (OPCs) are thought to ma

146 ese mice have overactivated Wnt signaling in oligodendrocyte precursor cells (OPCs) because of a cond

147 tory and inhibitory neurons, astrocytes, and oligodendrocyte precursor cells (OPCs) but were absent f

148 We and others have shown that oligodendrocyte precursor cells (OPCs) can also be the c

149 , it was demonstrated that lineage-committed oligodendrocyte precursor cells (OPCs) can be converted

150 Oligodendrocyte precursor cells (OPCs) can be differenti

151 We showed previously that purified rat oligodendrocyte precursor cells (OPCs) can be induced by

152 We previously showed that oligodendrocyte precursor cells (OPCs) can be transforme

153 hereas induced expression of Nkx2.2 in early oligodendrocyte precursor cells (OPCs) causes precocious

154 We report that oligodendrocyte precursor cells (OPCs) contact sprouting

155 The appearance of oligodendrocyte precursor cells (OPCs) correlates with t

156 and transplantation of adult rat spinal cord oligodendrocyte precursor cells (OPCs) could enhance rem

157 Remyelination may fail because oligodendrocyte precursor cells (OPCs) do not completely

158 Many oligodendrocyte precursor cells (OPCs) do not differenti

159 ll-intrinsic timer helps control when rodent oligodendrocyte precursor cells (OPCs) exit the cell cyc

160 In the mammalian CNS, oligodendrocyte precursor cells (OPCs) express most neur

161 Oligodendrocyte precursor cells (OPCs) express NMDA rece

162 Oligodendrocyte precursor cells (OPCs) express receptors

163 During differentiation, oligodendrocyte precursor cells (OPCs) extend a network

164 rects the specification of motor neurons and oligodendrocyte precursor cells (OPCs) from neural proge

165 Oligodendrocyte precursor cells (OPCs) give rise to myel

166 Oligodendrocyte precursor cells (OPCs) give rise to myel

167 ansplantation of neural stem cells (NSCs) or oligodendrocyte precursor cells (OPCs) has been used to

168 Oligodendrocyte precursor cells (OPCs) have extraordinar

169 We find perivascular clustering of oligodendrocyte precursor cells (OPCs) in certain active

170 t hypoxia activates the ISR in primary mouse oligodendrocyte precursor cells (OPCs) in vitro and that

171 lly identified as a proliferative signal for oligodendrocyte precursor cells (OPCs) in vitro.

172 Jagged signalling via Notch receptors on oligodendrocyte precursor cells (OPCs) inhibits their di

173 This transformation of oligodendrocyte precursor cells (OPCs) into myelinating

174 Transplantation of oligodendrocyte precursor cells (OPCs) is a promising po

175 Adult oligodendrocyte precursor cells (OPCs) make up around 5-

176 rocytes are initially specified, after which oligodendrocyte precursor cells (OPCs) migrate and proli

177 To myelinate axons, oligodendrocyte precursor cells (OPCs) must stop dividin

178 cultured and exposed to media conditioned by oligodendrocyte precursor cells (OPCs) or differentiated

179 Oligodendrocyte precursor cells (OPCs) persist in substa

180 In the central nervous system, oligodendrocyte precursor cells (OPCs) proliferate and d

181 Addition of anacardic acid to cultured oligodendrocyte precursor cells (OPCs) rapidly increased

182 Oligodendrocyte precursor cells (OPCs) retain the capaci

183 Oligodendrocyte precursor cells (OPCs) sculpt neural cir

184 They differentiate from oligodendrocyte precursor cells (OPCs) that are produced

185 ral nervous system (CNS), are generated from oligodendrocyte precursor cells (OPCs) that express neur

186 the central nervous system and develop from oligodendrocyte precursor cells (OPCs) that must first m

187 le explanation is the inability of recruited oligodendrocyte precursor cells (OPCs) to complete remye

188 The differentiation of oligodendroglia from oligodendrocyte precursor cells (OPCs) to complex and ex

189 ent combined with the intrinsic inability of oligodendrocyte precursor cells (OPCs) to differentiate

190 f which represent a continuum from Pdgfra(+) oligodendrocyte precursor cells (OPCs) to distinct matur

191 Sox8 is known to be expressed in oligodendrocyte precursor cells (OPCs) together with oth

192 Oligodendrocyte precursor cells (OPCs) undergo an extens

193 udy, we found that, in injured optic nerves, oligodendrocyte precursor cells (OPCs) undergo transient

194 re, we conditionally deleted Mtor from adult oligodendrocyte precursor cells (OPCs) using Ng2-Cre(ERT

195 e absence of Gsx2 expression, an increase in oligodendrocyte precursor cells (OPCs) with a concomitan

196 Oligodendrocyte precursor cells (OPCs), a major glial ce

197 ly, we discovered that the fine processes of oligodendrocyte precursor cells (OPCs), a population of

198 yeloid cells, meningeal cells, proliferating oligodendrocyte precursor cells (OPCs), and a dense extr

199 n deep layer excitatory neurons and immature oligodendrocyte precursor cells (OPCs), and these contri

200 aberrant growth prior to malignancy only in oligodendrocyte precursor cells (OPCs), but not in any o

201 Neurons form bona fide synapses with oligodendrocyte precursor cells (OPCs), but the circuit

202 ive AMPARs by recording from rat optic nerve oligodendrocyte precursor cells (OPCs), known to express

203 ure of reparative remyelination initiated by oligodendrocyte precursor cells (OPCs), lead to irrevers

204 endogenous remyelination, driven by resident oligodendrocyte precursor cells (OPCs), might partially

205 They develop from oligodendrocyte precursor cells (OPCs), most of which di

206 us examined the functional roles of CSPGs on oligodendrocyte precursor cells (OPCs), oligodendrocytes

207 NG2 glia, also known as oligodendrocyte precursor cells (OPCs), play an importan

208 pe is the most prominently expressed S1PR in oligodendrocyte precursor cells (OPCs), selective modula

209 xclusively expressed in oligodendrocytes and oligodendrocyte precursor cells (OPCs), which migrate co

210 is known to exist: that between neurons and oligodendrocyte precursor cells (OPCs), yet their compos

211 wild-type controls, as was proliferation of oligodendrocyte precursor cells (OPCs).

212 -length LINGO-1 inhibited differentiation of oligodendrocyte precursor cells (OPCs).

213 ression and function of REST in neonatal rat oligodendrocyte precursor cells (OPCs).

214 itors sequentially produce motor neurons and oligodendrocyte precursor cells (OPCs).

215 e a novel role in white matter by modulating oligodendrocyte precursor cells (OPCs).

216 demyelination, as were numbers of CXCR4+NG2+ oligodendrocyte precursor cells (OPCs).

217 upport the survival and proliferation of rat oligodendrocyte precursor cells (OPCs).

218 ation program in existing or newly recruited oligodendrocyte precursor cells (OPCs).

219 ta receptors may mediate the effect of TH on oligodendrocyte precursor cells (OPCs).

220 lso expressed by some glial cells, including oligodendrocyte precursor cells (OPCs).

221 genes consistent with anatomically distinct oligodendrocyte precursor cells (OPCs).

222 enerated from a population of cells known as oligodendrocyte precursor cells (OPCs).

223 ic on primary cultures of murine neurons and oligodendrocyte precursor cells (OPCs).

224 ntenance of oligodendrocytes that arise from oligodendrocyte precursor cells (OPCs).

225 odegenerative conditions from brain resident oligodendrocyte precursor cells (OPCs).

226 actors involved in immune gene regulation in oligodendrocyte precursor cells (OPCs).

227 ial lineage selection, expanding the pool of oligodendrocyte precursor cells (OPCs).

228 re postmitotic and derive from proliferative oligodendrocyte precursor cells (OPCs).

229 of functionally mature oligodendrocytes from oligodendrocyte precursor cells (OPCs).

230 factor-2, a guidance factor for migration of oligodendrocyte precursor cells (OPCs).

231 nhibited the differentiation of purified rat oligodendrocyte precursor cells (OPCs).

232 al differentiation-promoting effect of TH on oligodendrocyte precursor cells (OPCs): unlike wild-type

233 Oligodendrocyte precursor cells (OPCs; PDGFRalpha+) prod

234 ues extends this active role by showing that oligodendrocyte precursors cells (OPCs) in the hippocamp

235 Human oligodendrocytes precursor cells (OPCs) were stimulated

236 NG2 cells, also known as oligodendrocyte precursor cells or polydendrocytes, whic

237 g the muscarinic acetylcholine receptor 1 in oligodendrocyte precursor cells, or promoting oligodendr

238 the proliferation of Sox2 stem cells and NG2 oligodendrocyte precursors cells originating in the SVZ

239 xons or do intrinsic properties of different oligodendrocyte precursor cell populations affect length

240 r glial fibrillary acidic protein (GFAP) and oligodendrocyte precursor cells positive for NG2 proteog

241 ral spinal OLIG2-expressing progenitors, pre-oligodendrocyte precursor cells (pre-OPCs) and OPCs from

242 ogenic intermediate progenitors known as pre-oligodendrocyte precursor cells (pre-OPCs) to precursors

243 Here we show that most oligodendrocyte precursor cells purified from postnatal

244 tate-methyltransferase (Gamt) did not affect oligodendrocyte precursor cell recruitment, but resulted

245 G2(+) glia, also known as polydendrocytes or oligodendrocyte precursor cells, represent a new entity

246 neuronal development, and maturation of the oligodendrocyte precursor cells responsible for axonal m

247 miniaturised in vitro retinal ganglion cell-oligodendrocyte precursor cell (RGC-OPC) co-cultures int

248 c MS lesions and that Notch1 is activated in oligodendrocyte precursor cells (see the related article

249 nt mode of inheritance, in vitro analysis in oligodendrocyte precursor cells showed that mutant prote

250 ural gene downregulation and the quantity of oligodendrocyte precursor cells specified is dependent o

251 art of the normal timer that determines when oligodendrocyte precursor cells stop dividing and differ

252 eduction of mature oligodendrocytes, but not oligodendrocyte precursor cells, suggesting triglial dys

253 This conditioned media also enhanced oligodendrocyte precursor cell survival, maturation and

254 n neurons, astrocytes, oligodendrocytes, and oligodendrocyte precursor cells that are related to thes

255 ived mediators influenced differentiation of oligodendrocyte precursor cells through a crosstalk with

256 signaling contributes to the decision of an oligodendrocyte precursor cell to differentiate-both dur

257 glia/macrophage to lesions nor a failure for oligodendrocyte precursor cells to differentiate and rem

258 itical in regulating the transition of adult oligodendrocyte precursor cells to mature OLs that is es

259 e, we demonstrate that fear learning induces oligodendrocyte precursor cells to proliferate and diffe

260 hat certain extracellular signals can induce oligodendrocyte precursor cells to revert to multipotent

261 possible reason is the lack of migration of oligodendrocyte precursor cells to the lesion.

262 efault of the resident stem/precursor cells (oligodendrocyte precursor cells) to differentiate into m

263 After single-cell phototoxic damage, oligodendrocyte precursor cells underwent programmed cel

264 NLGN3 is cleaved from both neurons and oligodendrocyte precursor cells via the ADAM10 sheddase.

265 Migration and density of oligodendrocyte precursor cells were normal; however, a

266 erating the correct numbers of WM but not GM oligodendrocyte precursor cells, whereas during astrocyt

267 ntracellular timer that helps determine when oligodendrocyte precursor cells withdraw from the cell c