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1 ssion from Sox2(+) 'early' to Sox2(-) 'late' oligodendrocyte progenitor.
2 sm involving crosstalk between microglia and oligodendrocyte progenitors.
3 ick and mouse models and in vitro culture of oligodendrocyte progenitors.
4 uted population of glial cells that serve as oligodendrocyte progenitors.
5 f4, plays an important role in maturation of oligodendrocyte progenitors.
6 ntiated mitosis in primary cultures of mouse oligodendrocyte progenitors.
7 , and CC1-, indicated a close resemblance to oligodendrocyte progenitors.
8 presence of a susceptible population of late oligodendrocyte progenitors.
9 els, but we could detect the alpha(1A)-AR in oligodendrocyte progenitors.
10 sed markers for astrocytes and for neural or oligodendrocyte progenitors.
11 cerebral white matter and targeted death of oligodendrocyte progenitors.
12 es the expression of myelin basic protein in oligodendrocyte progenitors.
13 s that the ectopic astrocytes originate from oligodendrocyte progenitors.
14 dendrocyte development was delayed such that oligodendrocyte progenitors accumulated inappropriately
15 results showing defective differentiation of oligodendrocyte progenitors after silencing specific HDA
16 evel, lack of yy1 arrests differentiation of oligodendrocyte progenitors after they exit from the cel
19 , revealed that it is similarly expressed in oligodendrocyte progenitors and not oligodendrocytes.
20 sis using gene expression profiling of A2B5+ oligodendrocyte progenitors and O4+ oligodendrocytes.
21 ndently inhibited the maturation of purified oligodendrocyte progenitors, and pharmacological inhibit
22 Immunohistochemical studies showed that late oligodendrocyte progenitors appear at gestational age 22
23 n of neural progenitors and specification of oligodendrocyte progenitors are completed with the forma
24 ignificance statement: It is recognized that oligodendrocyte progenitors are mechanosensitive cells.
25 hibition, we demonstrate that specified NG2+ oligodendrocyte progenitors are plastic cells, whose dec
26 ed in apoptosis and reduced proliferation of oligodendrocyte progenitors, as well as arrested maturat
27 cytotoxic effects on actively proliferating oligodendrocyte progenitors but much less on immature ol
33 Ca(2+) channels and receptors that regulate oligodendrocyte progenitor cell (OPC) and oligodendrocyt
35 d Ca(2+) channels (L-VOCCs) are required for oligodendrocyte progenitor cell (OPC) development, we ge
38 d increases both adult mouse and adult human oligodendrocyte progenitor cell (OPC) differentiation, i
39 s is enough to restrict them to an exclusive oligodendrocyte progenitor cell (OPC) fate during differ
40 he ventral telencephalon were generated, but oligodendrocyte progenitor cell (OPC) generation was sev
41 se (MAPK)-dependent pathway is implicated in oligodendrocyte progenitor cell (OPC) lineage progressio
42 re infants results in inflammation, arrested oligodendrocyte progenitor cell (OPC) maturation, and re
43 multiple sclerosis (PPMS) failed to promote oligodendrocyte progenitor cell (OPC) maturation, wherea
46 two nf1 orthologs in zebrafish and show that oligodendrocyte progenitor cell (OPC) numbers are increa
51 strates a unique role for Olig1 in promoting oligodendrocyte progenitor cell commitment, differentiat
52 mportant roles for Sox17 in controlling both oligodendrocyte progenitor cell cycle exit and different
54 elevant, FDA-approved compounds that promote oligodendrocyte progenitor cell differentiation and indu
55 CN3 is a matricellular protein that promotes oligodendrocyte progenitor cell differentiation and myel
57 endrocyte lineage cells completely inhibited oligodendrocyte progenitor cell differentiation and myel
58 tory supernatants also resulted in decreased oligodendrocyte progenitor cell differentiation without
59 also explore the effect of these changes on oligodendrocyte progenitor cell differentiation, which i
64 process formation were also inhibited in the oligodendrocyte progenitor cell line CG-4 after suppress
65 of transplanted cells co-labeled for NG2, an oligodendrocyte progenitor cell marker, but not for neur
66 urons and astrocytes remains the same, early oligodendrocyte progenitor cell markers are decreased in
69 signaling increases neurogenesis and reduces oligodendrocyte progenitor cell proliferation (OPC) in t
70 infiltrates and demyelination, and increased oligodendrocyte progenitor cell proliferation and BDNF+
72 gh combined doses of oral antibiotics impair oligodendrocyte progenitor cell responses during remyeli
73 /or indirectly (via astrocytes) impact human oligodendrocyte progenitor cell survival and differentia
75 NS cells expressing A2B5, an early marker in oligodendrocytes progenitor cell differentiation as well
76 se embryonic and lung fibroblasts to induced oligodendrocyte progenitor cells (iOPCs) using sets of e
78 e found that AXIN2 was expressed in immature oligodendrocyte progenitor cells (OLPs) in white matter
79 erived growth factor receptor alpha-positive oligodendrocyte progenitor cells (OPC) located within th
80 ntiate human embryonic stem cells (hESCs) to oligodendrocyte progenitor cells (OPCs) according to dev
81 nsequences of disrupting Fth iron storage in oligodendrocyte progenitor cells (OPCs) after demyelinat
82 se genes was measured in primary neurons and oligodendrocyte progenitor cells (OPCs) after inflammato
85 in vitro primary rat embryonic cell model of oligodendrocyte progenitor cells (OPCs) and a mouse N20.
86 hogenetic protein (BMP) signaling pathway in oligodendrocyte progenitor cells (OPCs) and suppresses r
87 expression in the developing CNS identifies oligodendrocyte progenitor cells (OPCs) and whose activa
88 , both the proliferation and total number of oligodendrocyte progenitor cells (OPCs) appeared normal
89 ination and why remyelination is absent when oligodendrocyte progenitor cells (OPCs) are present.
91 termination of proliferation determines when oligodendrocyte progenitor cells (OPCs) can initiate dif
94 ular mechanisms that drive the maturation of oligodendrocyte progenitor cells (OPCs) during the remye
95 l myelinating glial cells, centrally derived oligodendrocyte progenitor cells (OPCs) ectopically exit
96 fish, we observed that prior to myelination, oligodendrocyte progenitor cells (OPCs) extend processes
97 factor-1 (IGF-1) provides neuroprotection to oligodendrocyte progenitor cells (OPCs) following cerebr
98 y also be a radial component of migration of oligodendrocyte progenitor cells (OPCs) from a ventral s
100 mice also exhibited an increased density of oligodendrocyte progenitor cells (OPCs) in CNS white mat
102 e show that the expression of Sox2 occurs in oligodendrocyte progenitor cells (OPCs) in rodent models
103 fficulties in generating pure populations of oligodendrocyte progenitor cells (OPCs) in sufficient qu
104 ion, and may contribute to the production of oligodendrocyte progenitor cells (OPCs) in the dorsal co
106 of human embryonic stem cell (hESC)-derived oligodendrocyte progenitor cells (OPCs) into adult rat s
108 n obligatory step for the differentiation of oligodendrocyte progenitor cells (OPCs) into myelinating
109 in disorders can be treated by transplanting oligodendrocyte progenitor cells (OPCs) into the affecte
111 ted failure to produce oligodendrocytes from oligodendrocyte progenitor cells (OPCs) is associated wi
112 cal changes, while in developing neurons and oligodendrocyte progenitor cells (OPCs) it induces cellu
113 lutamatergic synapses onto adult-born NG2(+) oligodendrocyte progenitor cells (OPCs) migrating from t
114 t oligodendrocytes, whether by transplanting oligodendrocyte progenitor cells (OPCs) or by mobilizing
115 n which Tsc1 is deleted by Cre expression in oligodendrocyte progenitor cells (OPCs) or in premyelina
119 ination of the central nervous system (CNS), oligodendrocyte progenitor cells (OPCs) proliferate and
123 White matter stroke stimulates adjacent oligodendrocyte progenitor cells (OPCs) to divide and mi
124 isoprenoid and cholesterol synthesis, causes oligodendrocyte progenitor cells (OPCs) to migrate past
125 er, direct injection of neural stem cells or oligodendrocyte progenitor cells (OPCs) to the lesion si
126 in which we targeted Notch1 inactivation to oligodendrocyte progenitor cells (OPCs) using Olig1Cre a
127 ation by blocking the differentiation of rat oligodendrocyte progenitor cells (OPCs) via modulation o
128 Many chronically demyelinated lesions have oligodendrocyte progenitor cells (OPCs) within their bor
130 and support cytocompatible encapsulation of oligodendrocyte progenitor cells (OPCs), as well as thei
131 mong three macroglial progenitor populations-oligodendrocyte progenitor cells (OPCs), astrocytes and
132 plaque-associated Olig2- and NG2-expressing oligodendrocyte progenitor cells (OPCs), but not astrocy
133 rect effects on the myelinating potential of oligodendrocyte progenitor cells (OPCs), in addition to
137 tly characterized by scarce undifferentiated oligodendrocyte progenitor cells (OPCs), suggesting the
138 gene expression profiling on purified murine oligodendrocyte progenitor cells (OPCs), the remyelinati
139 rve conduction, and the ectopic migration of oligodendrocyte progenitor cells (OPCs), the resident my
140 rotein fibronectin perturb the maturation of oligodendrocyte progenitor cells (OPCs), thereby impedin
141 oliferation is not altered in Seh1-deficient oligodendrocyte progenitor cells (OPCs), they fail to di
144 cells produces first motor neurons and then oligodendrocyte progenitor cells (OPCs), which migrate,
145 and generate de novo synapses with recruited oligodendrocyte progenitor cells (OPCs), which, early af
166 of betaT4-positive cells with A2B5-positive oligodendrocyte progenitor cells after transplantation (
167 peroxia showed a reduced capacity to protect oligodendrocyte progenitor cells against the toxic effec
168 e of the TUJ-1-positive cells, A2B5-positive oligodendrocyte progenitor cells and A2B5-negative cells
169 by an expression pattern resembling that of oligodendrocyte progenitor cells and carries a distincti
174 ation that human embryonic stem cell-derived oligodendrocyte progenitor cells are susceptible to JC v
175 nical translation: first, transplantation of oligodendrocyte progenitor cells as a means of treating
176 vides direct evidence that targeting EGFR in oligodendrocyte progenitor cells at a specific time afte
178 pression of syntaxin 4 but not syntaxin 3 in oligodendrocyte progenitor cells but not immature oligod
180 and constitutive ablation of NR1 in neonatal oligodendrocyte progenitor cells did not interrupt their
181 ous system (CNS) most often is the result of oligodendrocyte progenitor cells differentiating into my
183 brinogen inhibits nerve repair by preventing oligodendrocyte progenitor cells from differentiating in
184 cal studies revealed that the recruitment of oligodendrocyte progenitor cells in response to demyelin
185 e fifth major cell population that serves as oligodendrocyte progenitor cells in the postnatal CNS.
187 ly tune axonal diameter, promote re-entry of oligodendrocyte progenitor cells into the cell cycle, or
188 this mild inflammatory environment promotes oligodendrocyte progenitor cells maturation and myelin r
189 on rather than uncontrolled proliferation of oligodendrocyte progenitor cells may have important impl
190 immature oligodendrocyte-lineage cells, with oligodendrocyte progenitor cells more vulnerable to inju
191 In the absence of ERK1/ERK2 signaling NG2(+) oligodendrocyte progenitor cells proliferated and differ
193 noted because Nkx2.2 promotes maturation of oligodendrocyte progenitor cells specified by expression
194 w that miconazole and clobetasol function in oligodendrocyte progenitor cells through mitogen-activat
195 ibility of human embryonic stem cell-derived oligodendrocyte progenitor cells to infection with JC vi
196 y changes during the transition from A2B5(+) oligodendrocyte progenitor cells to premyelinating GalC(
197 man adult brain-derived oligodendrocytes and oligodendrocyte progenitor cells under conditions of met
200 rability of O4+ preoligodendrocytes, whereas oligodendrocyte progenitor cells were resistant to insul
201 o explore the mechanism of redistribution of oligodendrocyte progenitor cells with compensatory myeli
202 S immune milieu and concurrent activation of oligodendrocyte progenitor cells with subsequent remyeli
203 ng inflammatory injury, oligodendrocytes and oligodendrocyte progenitor cells within lesion sites are
204 r for cell proliferation), NG2 (a marker for oligodendrocyte progenitor cells) and brain-derived neur
205 56 regulates cortical lamination, whereas in oligodendrocyte progenitor cells, GPR56 controls develop
206 arative capabilities, and transplantation of oligodendrocyte progenitor cells, have generated substan
207 ed to the expansion of genetically wild-type oligodendrocyte progenitor cells, oligodendrocyte differ
208 uced myelin were examined for remyelination, oligodendrocyte progenitor cells, reactive astrocytes, a
209 sis, remyelination can fail despite abundant oligodendrocyte progenitor cells, suggesting impairment
210 d with a truncated proliferative response of oligodendrocyte progenitor cells, suggesting that deplet
211 ds for enhancing myelination from endogenous oligodendrocyte progenitor cells, we screened a library
212 ze the effects of BCNU on clonal cultures of oligodendrocyte progenitor cells-one of the best-charact
224 compression on the function and survival of oligodendrocyte progenitor cells/oligodendrocytes and ax
225 els to selectively delete TACE expression in oligodendrocyte progenitors cells (OPs), we found that T
226 alpha)-expressing stromal cells derived from oligodendrocytes progenitor cells (OPC) were discovered
228 te and determined whether transplanted adult oligodendrocyte progenitors could remyelinate the chroni
229 found that, in the absence of Schwann cells, oligodendrocyte progenitors cross ventral root transitio
230 tem inflammation as well as promoting neural/oligodendrocyte progenitor development in the offspring.
231 efects in PLP1 mRNA expression and splicing, oligodendrocyte progenitor development, and oligodendroc
232 treatment, and was associated with enhanced oligodendrocyte progenitor differentiation and epigeneti
233 effect of three mechanical stimuli on mouse oligodendrocyte progenitor differentiation and identify
234 est that NFIA participates in the control of oligodendrocyte progenitor differentiation and may contr
235 indicate that NFIA is sufficient to suppress oligodendrocyte progenitor differentiation during adult
236 scription factor nuclear factor IA (NFIA) in oligodendrocyte progenitor differentiation during develo
237 tral nervous system lesions are required for oligodendrocyte progenitor differentiation into remyelin
240 l enlargement of the Olig2/Nkx2.2-expressing oligodendrocyte progenitor domain, whereas conditional H
242 Taken together, these data suggest that for oligodendrocyte progenitors, ErbB2 signaling plays a rol
243 ptional network regulating the transition of oligodendrocyte progenitors from cell cycle exit to diff
245 regions of proneural tumors were enriched in oligodendrocyte progenitor genes, whereas the NE regions
247 which to accelerate differentiation of human oligodendrocyte progenitors (hOPCs) directly, we used CD
248 genitors during brain tumorigenesis, wherein oligodendrocyte-progenitor intermediates are abundant, h
249 of neurons, and may regulate the function of oligodendrocyte progenitors, interneurons, GABA, and NMD
251 CNS laminin is to promote the development of oligodendrocyte progenitors into myelin-forming oligoden
252 is inhibited by impaired differentiation of oligodendrocyte progenitors into myelin-producing oligod
254 transition from multipotential precursors to oligodendrocyte progenitors is associated with the progr
257 droitin sulfate proteoglycan-NG2(+) and late oligodendrocyte progenitor marker(+)), and terminal-diff
258 ssociation with myelin, without reexpressing oligodendrocyte progenitor markers or reentering the cel
259 ly rarely found to be immunoreactive against oligodendrocyte progenitor markers such as NG2 or PDGFRa
260 Myelin regeneration requires endogenous oligodendrocyte progenitor migration and activation of t
261 be a critical molecule in the regulation of oligodendrocyte progenitor migration and myelination.
262 ransfer glycolytic substrates to neurons and oligodendrocyte progenitors (NG2(+) cells) exhibit enhan
263 re population has long been considered to be oligodendrocyte progenitors, numerous NG2(+) cells are p
271 (TGFbeta) signaling is crucial for allowing oligodendrocyte progenitor (OP) cell cycle withdrawal, a
274 mice with sustained activation of ERK1/2 in oligodendrocyte progenitors (OPCs), oligodendrocytes, an
275 ccumulation in pluripotent-stem-cell-derived oligodendrocyte progenitors (OPCs), we demonstrate that
277 nction between subcortical white matter NG2+ oligodendrocyte progenitors (OPs) and O4+ preoligodendro
278 ) expression and survival of differentiating oligodendrocyte progenitors (OPs) in proinflammatory cyt
279 ion of both postmitotic oligodendrocytes and oligodendrocyte progenitors (OPs) is the major hallmark
280 The abundance and widespread distribution of oligodendrocyte progenitors (OPs) within the adult CNS a
283 rsely, overexpression of MRF within cultured oligodendrocyte progenitors or the chick spinal cord pro
284 ncluding radial glia (GFAP+, vimentin+), and oligodendrocyte progenitors (PDGFR-alpha+) were prolifer
291 stration of rmTIMP-1 to A2B5(+) immunopanned oligodendrocyte progenitors significantly increased the
294 and LINC complex, mediate nuclear changes in oligodendrocyte progenitors that favor a default pathway
296 ates were found to promote the transition of oligodendrocyte progenitors to newly formed oligodendroc
297 , the presence of susceptible populations of oligodendrocyte progenitors underlies regional predilect
298 as well as after transplantation of t(1;11) oligodendrocyte progenitors were significantly reduced w
299 erivation and prospective isolation of human oligodendrocyte progenitors, which, upon transplantation
300 ta was also detected in NG2 cells (potential oligodendrocyte progenitors) within the white matter and