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1 require technologies to generate functional oligodendrocyte progenitor cells.
2 lates cell cycle exit and differentiation in oligodendrocyte progenitor cells.
3 otential for recovery mediated by endogenous oligodendrocyte progenitor cells.
4 O mice revealed a specific deficit of NG2(+) oligodendrocyte progenitor cells.
5 s have dramatically increased numbers of CNS oligodendrocyte progenitor cells.
6 mmunocytochemically for oligodendrocytes and oligodendrocyte progenitor cells.
7 white matter is synthesized by proliferating oligodendrocyte progenitor cells.
8 ransplantation or manipulation of endogenous oligodendrocyte progenitor cells.
9 hondroitin sulfate proteoglycan expressed by oligodendrocyte progenitor cells.
10 tors of proliferation and differentiation of oligodendrocyte progenitor cells.
11 ns and mice, between reactive astrocytes and oligodendrocyte progenitor cells.
12 ves differentiation of oligodendrocytes from oligodendrocyte progenitor cells.
13 mote production of new oligodendrocytes from oligodendrocyte progenitor cells.
14 tire CNS after they have differentiated from oligodendrocyte progenitor cells.
15 ouse for voltage-operated Ca(2+) channels in oligodendrocyte progenitor cells.
16 mouse pluripotent epiblast stem-cell-derived oligodendrocyte progenitor cells.
17 ndent on the survival and differentiation of oligodendrocyte progenitor cells.
18 of betaT4-positive cells with A2B5-positive oligodendrocyte progenitor cells after transplantation (
19 peroxia showed a reduced capacity to protect oligodendrocyte progenitor cells against the toxic effec
21 e of the TUJ-1-positive cells, A2B5-positive oligodendrocyte progenitor cells and A2B5-negative cells
22 by an expression pattern resembling that of oligodendrocyte progenitor cells and carries a distincti
23 and in our studies, primary cultures of both oligodendrocyte progenitor cells and differentiating oli
25 he cellular factors involved in apoptosis of oligodendrocyte progenitor cells and oligodendrocytes, a
26 r for cell proliferation), NG2 (a marker for oligodendrocyte progenitor cells) and brain-derived neur
28 cific regulatory changes were accelerated in oligodendrocyte progenitor cells, and we highlight key b
32 ation that human embryonic stem cell-derived oligodendrocyte progenitor cells are susceptible to JC v
33 nical translation: first, transplantation of oligodendrocyte progenitor cells as a means of treating
34 vides direct evidence that targeting EGFR in oligodendrocyte progenitor cells at a specific time afte
36 alphavveta3 integrin may play in regulating oligodendrocyte progenitor cell behaviour, cells of the
37 pression of syntaxin 4 but not syntaxin 3 in oligodendrocyte progenitor cells but not immature oligod
40 strates a unique role for Olig1 in promoting oligodendrocyte progenitor cell commitment, differentiat
41 nriched for astrocytes, oligodendrocytes and oligodendrocyte progenitor cells containing the genes C4
42 mportant roles for Sox17 in controlling both oligodendrocyte progenitor cell cycle exit and different
44 and constitutive ablation of NR1 in neonatal oligodendrocyte progenitor cells did not interrupt their
45 ous system (CNS) most often is the result of oligodendrocyte progenitor cells differentiating into my
46 elevant, FDA-approved compounds that promote oligodendrocyte progenitor cell differentiation and indu
48 endrocyte lineage cells completely inhibited oligodendrocyte progenitor cell differentiation and myel
49 CN3 is a matricellular protein that promotes oligodendrocyte progenitor cell differentiation and myel
50 tory supernatants also resulted in decreased oligodendrocyte progenitor cell differentiation without
51 also explore the effect of these changes on oligodendrocyte progenitor cell differentiation, which i
56 romote remyelination by enhancing endogenous oligodendrocyte progenitor cells differentiation and by
57 NS cells expressing A2B5, an early marker in oligodendrocytes progenitor cell differentiation as well
59 cortex regions, while excitatory neurons and oligodendrocyte progenitor cells emerged as the major ce
62 brinogen inhibits nerve repair by preventing oligodendrocyte progenitor cells from differentiating in
65 56 regulates cortical lamination, whereas in oligodendrocyte progenitor cells, GPR56 controls develop
66 arative capabilities, and transplantation of oligodendrocyte progenitor cells, have generated substan
68 minimally invasive delivery of primary human oligodendrocyte progenitor cells (hOPCs) to the brain of
70 ely, from proliferating local astrocytes and oligodendrocyte progenitor cells in adult mice of both s
71 cal studies revealed that the recruitment of oligodendrocyte progenitor cells in response to demyelin
72 us studies have suggested the persistence of oligodendrocyte progenitor cells in the adult mammalian
73 e fifth major cell population that serves as oligodendrocyte progenitor cells in the postnatal CNS.
75 e-cell population is relatively enriched for oligodendrocyte-progenitor cells in the cortex versus th
77 ly tune axonal diameter, promote re-entry of oligodendrocyte progenitor cells into the cell cycle, or
78 netic nanoparticles, and transplanted tagged oligodendrocyte progenitor cells into the spinal cord of
80 se embryonic and lung fibroblasts to induced oligodendrocyte progenitor cells (iOPCs) using sets of e
81 a novel mechanism by which proliferation of oligodendrocyte progenitor cells is regulated in the pos
82 er cell metabolic crosstalk during proneural/oligodendrocyte progenitor cell-like to mesenchymal-like
83 process formation were also inhibited in the oligodendrocyte progenitor cell line CG-4 after suppress
85 of transplanted cells co-labeled for NG2, an oligodendrocyte progenitor cell marker, but not for neur
86 urons and astrocytes remains the same, early oligodendrocyte progenitor cell markers are decreased in
88 this mild inflammatory environment promotes oligodendrocyte progenitor cells maturation and myelin r
89 of an early oligodendrocytic promoter, these oligodendrocyte progenitor cells may be extracted and pu
90 on rather than uncontrolled proliferation of oligodendrocyte progenitor cells may have important impl
92 aling in establishing a motile phenotype for oligodendrocyte progenitor cell migration in vivo and il
93 immature oligodendrocyte-lineage cells, with oligodendrocyte progenitor cells more vulnerable to inju
94 bient RNA removal, we detect rare, committed oligodendrocyte progenitor cells not annotated in most p
96 Many physiologically important activities of oligodendrocyte progenitor cells (O-2A cells), including
97 g development of the central nervous system, oligodendrocyte progenitor cells (O-2A) undergo an order
99 ed to the expansion of genetically wild-type oligodendrocyte progenitor cells, oligodendrocyte differ
101 compression on the function and survival of oligodendrocyte progenitor cells/oligodendrocytes and ax
102 e found that AXIN2 was expressed in immature oligodendrocyte progenitor cells (OLPs) in white matter
103 ze the effects of BCNU on clonal cultures of oligodendrocyte progenitor cells-one of the best-charact
105 Ca(2+) channels and receptors that regulate oligodendrocyte progenitor cell (OPC) and oligodendrocyt
107 udies of TBI victims demonstrate significant oligodendrocyte progenitor cell (OPC) death post TBI; an
108 d Ca(2+) channels (L-VOCCs) are required for oligodendrocyte progenitor cell (OPC) development, we ge
111 d increases both adult mouse and adult human oligodendrocyte progenitor cell (OPC) differentiation, i
113 s is enough to restrict them to an exclusive oligodendrocyte progenitor cell (OPC) fate during differ
116 he ventral telencephalon were generated, but oligodendrocyte progenitor cell (OPC) generation was sev
117 se (MAPK)-dependent pathway is implicated in oligodendrocyte progenitor cell (OPC) lineage progressio
118 reased microglial phagocytosis, and improved oligodendrocyte progenitor cell (OPC) maturation in kits
119 re infants results in inflammation, arrested oligodendrocyte progenitor cell (OPC) maturation, and re
120 multiple sclerosis (PPMS) failed to promote oligodendrocyte progenitor cell (OPC) maturation, wherea
123 two nf1 orthologs in zebrafish and show that oligodendrocyte progenitor cell (OPC) numbers are increa
129 We show that inhibition of PDE4D boosts oligodendrocyte progenitor cells (OPC) differentiation a
131 erived growth factor receptor alpha-positive oligodendrocyte progenitor cells (OPC) located within th
132 ervous system (CNS) cell types revealed that oligodendrocyte progenitor cells (OPC), the largest popu
135 alpha)-expressing stromal cells derived from oligodendrocytes progenitor cells (OPC) were discovered
136 ntiate human embryonic stem cells (hESCs) to oligodendrocyte progenitor cells (OPCs) according to dev
138 nsequences of disrupting Fth iron storage in oligodendrocyte progenitor cells (OPCs) after demyelinat
139 se genes was measured in primary neurons and oligodendrocyte progenitor cells (OPCs) after inflammato
142 isruption of the syntenic insulator in mouse oligodendrocyte progenitor cells (OPCs) allows an OPC-sp
144 in vitro primary rat embryonic cell model of oligodendrocyte progenitor cells (OPCs) and a mouse N20.
145 ation at the same site, eventually depleting oligodendrocyte progenitor cells (OPCs) and exhausting t
146 overexpressing mice harbor enlarged pools of oligodendrocyte progenitor cells (OPCs) and show greater
147 hogenetic protein (BMP) signaling pathway in oligodendrocyte progenitor cells (OPCs) and suppresses r
148 expression in the developing CNS identifies oligodendrocyte progenitor cells (OPCs) and whose activa
149 , both the proliferation and total number of oligodendrocyte progenitor cells (OPCs) appeared normal
150 ination and why remyelination is absent when oligodendrocyte progenitor cells (OPCs) are present.
152 ouse forebrain, temporally distinct waves of oligodendrocyte progenitor cells (OPCs) arise from diffe
154 termination of proliferation determines when oligodendrocyte progenitor cells (OPCs) can initiate dif
159 ular mechanisms that drive the maturation of oligodendrocyte progenitor cells (OPCs) during the remye
160 l myelinating glial cells, centrally derived oligodendrocyte progenitor cells (OPCs) ectopically exit
162 fish, we observed that prior to myelination, oligodendrocyte progenitor cells (OPCs) extend processes
163 factor-1 (IGF-1) provides neuroprotection to oligodendrocyte progenitor cells (OPCs) following cerebr
164 y also be a radial component of migration of oligodendrocyte progenitor cells (OPCs) from a ventral s
166 mice also exhibited an increased density of oligodendrocyte progenitor cells (OPCs) in CNS white mat
168 er agents with prodifferentiative effects on oligodendrocyte progenitor cells (OPCs) in rodent models
169 e show that the expression of Sox2 occurs in oligodendrocyte progenitor cells (OPCs) in rodent models
170 fficulties in generating pure populations of oligodendrocyte progenitor cells (OPCs) in sufficient qu
171 filtrative cells mirrors that of uncommitted oligodendrocyte progenitor cells (OPCs) in the developin
172 ion, and may contribute to the production of oligodendrocyte progenitor cells (OPCs) in the dorsal co
174 of human embryonic stem cell (hESC)-derived oligodendrocyte progenitor cells (OPCs) into adult rat s
176 n obligatory step for the differentiation of oligodendrocyte progenitor cells (OPCs) into myelinating
177 in disorders can be treated by transplanting oligodendrocyte progenitor cells (OPCs) into the affecte
180 ment.SIGNIFICANCE STATEMENT The migration of oligodendrocyte progenitor cells (OPCs) is an essential
181 ted failure to produce oligodendrocytes from oligodendrocyte progenitor cells (OPCs) is associated wi
182 cal changes, while in developing neurons and oligodendrocyte progenitor cells (OPCs) it induces cellu
183 t impairs recruitment and differentiation of oligodendrocyte progenitor cells (OPCs) leading to faile
184 lutamatergic synapses onto adult-born NG2(+) oligodendrocyte progenitor cells (OPCs) migrating from t
185 expression of the Tf receptor (Tfr) gene in oligodendrocyte progenitor cells (OPCs) on mice of eithe
186 t oligodendrocytes, whether by transplanting oligodendrocyte progenitor cells (OPCs) or by mobilizing
187 n which Tsc1 is deleted by Cre expression in oligodendrocyte progenitor cells (OPCs) or in premyelina
191 ination of the central nervous system (CNS), oligodendrocyte progenitor cells (OPCs) proliferate and
195 White matter stroke stimulates adjacent oligodendrocyte progenitor cells (OPCs) to divide and mi
196 isoprenoid and cholesterol synthesis, causes oligodendrocyte progenitor cells (OPCs) to migrate past
198 er, direct injection of neural stem cells or oligodendrocyte progenitor cells (OPCs) to the lesion si
199 in which we targeted Notch1 inactivation to oligodendrocyte progenitor cells (OPCs) using Olig1Cre a
200 ation by blocking the differentiation of rat oligodendrocyte progenitor cells (OPCs) via modulation o
201 osis, induces pathologic quiescence in human oligodendrocyte progenitor cells (OPCs) via upregulation
202 Many chronically demyelinated lesions have oligodendrocyte progenitor cells (OPCs) within their bor
204 and support cytocompatible encapsulation of oligodendrocyte progenitor cells (OPCs), as well as thei
205 mong three macroglial progenitor populations-oligodendrocyte progenitor cells (OPCs), astrocytes and
206 plaque-associated Olig2- and NG2-expressing oligodendrocyte progenitor cells (OPCs), but not astrocy
207 rect effects on the myelinating potential of oligodendrocyte progenitor cells (OPCs), in addition to
211 tly characterized by scarce undifferentiated oligodendrocyte progenitor cells (OPCs), suggesting the
212 gene expression profiling on purified murine oligodendrocyte progenitor cells (OPCs), the remyelinati
213 rve conduction, and the ectopic migration of oligodendrocyte progenitor cells (OPCs), the resident my
214 rotein fibronectin perturb the maturation of oligodendrocyte progenitor cells (OPCs), thereby impedin
215 oliferation is not altered in Seh1-deficient oligodendrocyte progenitor cells (OPCs), they fail to di
216 t transferrin receptor (Tfr) specifically in oligodendrocyte progenitor cells (OPCs), we have establi
219 cells produces first motor neurons and then oligodendrocyte progenitor cells (OPCs), which migrate,
220 and generate de novo synapses with recruited oligodendrocyte progenitor cells (OPCs), which, early af
247 nated is crucial to our understanding of how oligodendrocyte progenitor cells (OPs) develop into myel
250 els to selectively delete TACE expression in oligodendrocyte progenitors cells (OPs), we found that T
252 mbryonic forebrain, developmentally distinct oligodendrocyte progenitor cell populations and their pr
253 migration, survival, and differentiation of oligodendrocyte progenitor cells, precursors to myelin-f
255 In the absence of ERK1/ERK2 signaling NG2(+) oligodendrocyte progenitor cells proliferated and differ
256 signaling increases neurogenesis and reduces oligodendrocyte progenitor cell proliferation (OPC) in t
257 infiltrates and demyelination, and increased oligodendrocyte progenitor cell proliferation and BDNF+
260 uced myelin were examined for remyelination, oligodendrocyte progenitor cells, reactive astrocytes, a
264 gh combined doses of oral antibiotics impair oligodendrocyte progenitor cell responses during remyeli
265 blish that deletion of mTORC2 signaling from oligodendrocyte progenitor cells results in reduced myel
266 lack expression of Timp1 do not support rat oligodendrocyte progenitor cell (rOPC) differentiation,
267 enriched population of cells expressing the oligodendrocyte progenitor cell-specific marker NG2.
268 noted because Nkx2.2 promotes maturation of oligodendrocyte progenitor cells specified by expression
269 sis, remyelination can fail despite abundant oligodendrocyte progenitor cells, suggesting impairment
270 d with a truncated proliferative response of oligodendrocyte progenitor cells, suggesting that deplet
271 /or indirectly (via astrocytes) impact human oligodendrocyte progenitor cell survival and differentia
272 to eightfold greater number of proliferating oligodendrocyte progenitor cells than did wild-type (wt)
274 w that miconazole and clobetasol function in oligodendrocyte progenitor cells through mitogen-activat
275 ibility of human embryonic stem cell-derived oligodendrocyte progenitor cells to infection with JC vi
276 y changes during the transition from A2B5(+) oligodendrocyte progenitor cells to premyelinating GalC(
277 man adult brain-derived oligodendrocytes and oligodendrocyte progenitor cells under conditions of met
279 ds for enhancing myelination from endogenous oligodendrocyte progenitor cells, we screened a library
280 two populations of NG2 proteoglycan-positive oligodendrocyte progenitor cells were identified that ex
282 se developing axon-free nerves, 25 to 33% of oligodendrocyte progenitor cells were proliferating.
283 rability of O4+ preoligodendrocytes, whereas oligodendrocyte progenitor cells were resistant to insul
285 o explore the mechanism of redistribution of oligodendrocyte progenitor cells with compensatory myeli
286 S immune milieu and concurrent activation of oligodendrocyte progenitor cells with subsequent remyeli
287 ng inflammatory injury, oligodendrocytes and oligodendrocyte progenitor cells within lesion sites are