ライフサイエンスコーパス: oligodendroglial

1 e that, in the mature CNS, a fraction of the oligodendroglial 155 kDa isoform of neurofascin (NF-155)

2 s, these lesions were accompanied by pTDP-43 oligodendroglial aggregates.

3 Survivin up-regulation was also found in oligodendroglial and astrocytic cultures infected with J

4 Astrocytic, oligodendroglial and mixed gliomas are the commonest gli

5 ne expression profile enriched for synaptic, oligodendroglial- and schizophrenia-related genes.

6 trocytic reactivity, attenuated neuronal and oligodendroglial apoptosis and reduced the production of

7 dicate a role for glutamate as a mediator of oligodendroglial apoptosis in traumatic SCI.

8 n up-regulation associated with neuronal and oligodendroglial apoptosis, glial scar formation and mic

9 the extent of myelin loss, the frequency of oligodendroglial apoptosis, or CNS recruitment of macrop

10 ry occurrence, following T antigen-triggered oligodendroglial apoptosis.

11 We have used bipotent postnatal cortical oligodendroglial-astroglial progenitor cells (O-2As) to

12 body and T cell-mediated immune responses to oligodendroglial autoantigens transaldolase (TAL) and my

13 mitochondrial function, synaptic plasticity, oligodendroglial biology, cellular senescence, calcium a

14 mmon progenitor to determine neuronal versus oligodendroglial cell fate acquisition.

15 with concurrent suppression of neuronal and oligodendroglial cell fates.

16 nes sufficient to destroy the myelin-forming oligodendroglial cell in vitro.

17 thermore, knockdown of Zfp488 via RNAi in an oligodendroglial cell line leads to the downregulation o

18 Genomic BC200 deletion in an oligodendroglial cell line led to major transcriptomic a

19 Expression of the mutant proteins in an oligodendroglial cell line resulted in substantially red

20 growth factor (PDGF) was investigated in the oligodendroglial cell lines CG4 and CEINGE clone 3, usin

21 erestingly, activation of LXRs also promotes oligodendroglial cell maturation and remyelination after

22 Directed neuronal, astroglial, and oligodendroglial cell migrations comprise a prominent fe

23 ggest that alphavbeta3 integrin may regulate oligodendroglial cell proliferation and that both downre

24 haracterizing expression in human and rodent oligodendroglial cells (including those in human MS tiss

25 In contrast, deletion of Fth in oligodendroglial cells after postnatal day 60 has no eff

26 Importantly, deleting Fth in Sox10-positive oligodendroglial cells after postnatal day 60 has no eff

27 y in EAE, whereas the low level of Mn-SOD in oligodendroglial cells and axons may increase their vuln

28 onist-induced trafficking of native GPR17 in oligodendroglial cells and may have implications for bot

29 but synapses from axons onto myelin-forming oligodendroglial cells are not required.

30 ing differentiation of rat, mouse, and human oligodendroglial cells both in vivo and in vitro.

31 There was also a variable loss of oligodendroglial cells in the cerebral peduncle.

32 osis of injured, phosphatidylserine-exposing oligodendroglial cells is abrogated in the absence of AT

33 suggest that voltage-gated Ca(2+) influx in oligodendroglial cells is critical for normal myelinatio

34 st that Ca(2+) influx mediated by L-VGCCs in oligodendroglial cells is necessary for normal remyelina

35 their precursors rather than in neuronal or oligodendroglial cells is responsible for the reduction

36 Fth ablation in oligodendroglial cells throughout early postnatal develo

37 and a significant reduction in RIP-positive oligodendroglial cells were detected at day 7 post-injur

38 ally depends on the successful generation of oligodendroglial cells, a therapeutic need that is curre

39 , HLA-A2-transfected, but not control MO3.13 oligodendroglial cells, expressing high levels of endoge

40 vy subunit (Fth) was specifically deleted in oligodendroglial cells.

41 These oligodendroglial changes are evident selectively within

42 However, oligodendroglial Cmtm5 deficiency causes an early-onset

43 also observe in global and tamoxifen-induced oligodendroglial Cmtm5 mutants.

44 Tau-immunoreactive and Gallyas-positive oligodendroglial coiled bodies (similar to CBD and PSP),

45 Gallyas-positive neuropil threads and oligodendroglial coiled bodies were also observed.

46 pretangles/neurofibrillary tangles, threads, oligodendroglial coiled bodies, tufted astrocytes, and a

47 ggest that S1P could be a part of the neuron-oligodendroglial communication network regulating OPC mi

48 Clinical protocols to treat oligodendroglial-containing tumors, brain lymphoma or pr

49 terferon-gamma (IFNG) on highly purified rat oligodendroglial cultures at different developmental sta

50 Oligodendroglial cytoplasmic inclusions containing misfo

51 d gliosis as well as the frequency of glial (oligodendroglial) cytoplasmic inclusions (GCIs) and neur

52 or CCR3 chemokine receptor blockade rescued oligodendroglial deficits and cognitive performance in a

53 Here, we focus on mechanisms that underlie oligodendroglial deficits and dysmyelination in the prog

54 Here we report an unexpected role for oligodendroglial deficits in ANDS pathophysiology.

55 armacologically enhancing myelin renewal, by oligodendroglial deletion of the muscarinic M1 receptor

56 pic examination suggest that the increase in oligodendroglial density is not a consequence of atrophy

57 these findings show that Nf1 mutation delays oligodendroglial development and disrupts activity-depen

58 ein levels showed dynamic alterations during oligodendroglial development and following oxidative str

59 ription factor Olig2 is expressed throughout oligodendroglial development and is essential for oligod

60 Scribble is expressed throughout oligodendroglial development and is up-regulated in matu

61 to perform long-term tracking of neural and oligodendroglial development in the large-scale human ce

62 OPC-specific Nf1 loss impairs oligodendroglial differentiation and abrogates the norma

63 ligodendrocyte precursor cells, or promoting oligodendroglial differentiation and myelination via cle

64 ts suggest that the C5aR may be a marker for oligodendroglial differentiation and play a role in olig

65 p2 gene encodes one such potent inhibitor of oligodendroglial differentiation and this study sheds li

66 A minority of tumours with oligodendroglial differentiation are chemosensitive and

67 absence of Brg1 points to a contribution to oligodendroglial differentiation but also shows that the

68 TLR4 results in an overall reduction of the oligodendroglial differentiation capacity, thereby contr

69 hibit, TCF7l2 signaling to overcome arrested oligodendroglial differentiation in multiple sclerosis a

70 O-2A progenitor cells undergo progressive oligodendroglial differentiation when cultured in serum-

71 des both instructive and inhibitory cues for oligodendroglial differentiation, depending on the devel

72 at beta-catenin is dispensable for postnatal oligodendroglial differentiation, that Apc one-allele de

73 and astroglial differentiation and inhibited oligodendroglial differentiation, whereas 100 ng/ml BMP2

74 HLH cooperation can serve as a mechanism for oligodendroglial differentiation.

75 to astrocytes with concurrent suppression of oligodendroglial differentiation.

76 rmacological compounds potentially promoting oligodendroglial differentiation.

77 accumulation of p57kip2 resulted in blocked oligodendroglial differentiation.

78 we investigated whether ENV protein affects oligodendroglial differentiation.

79 Degeneration of oligodendroglial distal processes has been identified as

80 all examined in light of the hypothesis that oligodendroglial dysfunction and even death, with subseq

81 , 1p loss of heterozygosity, the presence of oligodendroglial elements on microscopy, and MGMT promot

82 age, 1p loss of heterozygosity, presence of oligodendroglial elements, and MGMT promoter methylation

83 Deletion experiments indicated that an oligodendroglial enhancer located in the region from -6

84 yelinating stage are controversial, although oligodendroglial excitability is potentially important f

85 t oligodendrocyte precursors committed to an oligodendroglial fate, and CD24(+)THY1(-/lo) cells marke

86 he fate of these multipotent cells toward an oligodendroglial fate-a subgroup myelinated up to 52% (m

87 programs may explain the mixed neuronal and oligodendroglial features in these tumors.

88 ciprocal relationship in which neurons alter oligodendroglial form and oligodendrocytes conversely mo

89 tamic acid decarboxylase 65), as well as the oligodendroglial gene encoding CNPase (2',3' cyclic nucl

90 Thus, neuronal and oligodendroglial gene products are present in a subset o

91 The neuronal and oligodendroglial genes expressed in ex vivo bone marrow

92 q13-15 and expression of both astrocytic and oligodendroglial genes.

93 l care of adult patients with astrocytic and oligodendroglial gliomas, including glioblastomas.

94 ctivity-dependent glutamate release enhances oligodendroglial glucose uptake and glycolytic support o

95 Following induction with myelin oligodendroglial glycoprotein (MOG) peptide 35-55 in CFA

96 transgenic, or retrogenic, models of myelin oligodendroglial glycoprotein (MOG)-induced experimental

97 their immunomodulatory properties in myelin oligodendroglial glycoprotein-induced experimental aller

98 Our findings of an altered oligodendroglial heterogeneity in MS may be important fo

99 suggest the potential of intervening with an oligodendroglial HIFa-mediated signaling pathway to miti

100 e supporting an alternative understanding of oligodendroglial HIFa-regulated developmental myelinatio

101 Together, our in vivo data demonstrate that oligodendroglial HIFalpha regulates CNS angiogenesis thr

102 suggest the potential of intervening with an oligodendroglial HIFalpha-mediated signaling pathway to

103 ved VEGF but not Wnt significantly decreases oligodendroglial HIFalpha-regulated CNS angiogenesis.

104 e supporting an alternative understanding of oligodendroglial HIFalpha-regulated developmental myelin

105 odified grade, 1p/19q codeletion status, and oligodendroglial histology for the 586 HGGs analyzed by

106 gnosis, endothelial proliferation, necrosis, oligodendroglial histology, treatment center, and chromo

107 findings in early MS lesions, where a marked oligodendroglial histone deacetylation was observed.

108 Consequently, oligodendroglial homeostasis and hippocampal neurogenesi

109 e absence of a correlation between increased oligodendroglial infection and the extent of demyelinati

110 cerebral white matter lesions with prominent oligodendroglial injury and loss, a disorder termed peri

111 evelopment and throughout adult life, neuron-oligodendroglial interactions shape activity and experie

112 lation of the biophysical elements of axonal-oligodendroglial interactions.

113 In this study, we identify an oligodendroglial-intrinsic factor that controls OL matur

114 Axonal Kv7 (outward-rectifying) and oligodendroglial Kir4.1 (inward-rectifying) potassium ch

115 tional relationship between neuronal Kv7 and oligodendroglial Kir4.1 channels and assessed the transc

116 Mice lacking oligodendroglial Kir4.1 exhibit lower resting lactate le

117 d individual genes typically associated with oligodendroglial lineage (e.g., proteolipid protein and

118 ous polyposis coli (Apc) and its role in the oligodendroglial lineage are poorly understood.

119 pressing cells in the astroglial but not the oligodendroglial lineage are the essential source of rea

120 Oligodendroglial lineage cells respond to dopaminergic n

121 Acvr1(G328V) arrests the differentiation of oligodendroglial lineage cells, and cooperates with Hist

122 ulate beta-catenin-mediated Wnt signaling in oligodendroglial lineage cells, and that APC regulates o

123 gnate receptor (PDGF-alphaR) is expressed on oligodendroglial lineage cells, such cells are considere

124 t signaling in early postnatal but not adult oligodendroglial lineage cells.

125 that N-acetylaspartate is expressed also by oligodendroglial lineage cells.

126 tes and neurons but weaker in stem cells and oligodendroglial lineage cells.

127 BA(A) receptors (GABA(A)Rs) expressed in the oligodendroglial lineage contributes to the myelination

128 as a direct transcriptional repressor of the oligodendroglial lineage determinant Olig2.

129 noreactive APC is transiently induced in the oligodendroglial lineage during both normal myelination

130 erentiation of cells already committed to an oligodendroglial lineage during development.

131 Microglial depletion normalizes oligodendroglial lineage dynamics, myelin microstructure

132 ghts toward the cell of origin, highlighting oligodendroglial lineage genes, and reveals unexpected m

133 t PEDF to the medium enhanced expressions of oligodendroglial lineage markers (NG2 and PDGFralpha) an

134 GFAP:GFP- SVZ neural precursors coexpressing oligodendroglial lineage markers and transcription facto

135 Collectively, our data suggest that oligodendroglial lineage NMDARs are neither required for

136 in regulating canonical Wnt signaling in the oligodendroglial lineage or in the CNS.

137 o cholinergic motor neurons and cells of the oligodendroglial lineage sequentially.

138 romotes the elaboration of both neuronal and oligodendroglial lineage species and inhibits the effect

139 pregulated in a time-dependent manner in the oligodendroglial lineage within the lesion.

140 ich had been thought to be restricted to the oligodendroglial lineage, also unexpectedly gave rise to

141 and the relationship of synantocytes to the oligodendroglial lineage, in particular, remains controv

142 ired for timely postnatal development of the oligodendroglial lineage, nor significant participants i

143 system to conditionally ablate APC from the oligodendroglial lineage, we determined that APC enhance

144 s that Hdac3 interacts with p300 to activate oligodendroglial lineage-specific genes, while suppressi

145 atter (WM) by delaying the maturation of the oligodendroglial lineage.

146 ion but no defects in the development of the oligodendroglial lineage.

147 tipotent adult neural progenitor cells to an oligodendroglial lineage.

148 to commit to the astrocytic rather than the oligodendroglial lineage.

149 munoreactive for rip antibody, suggesting an oligodendroglial lineage.

150 is a Wnt effector induced transiently in the oligodendroglial lineage.

151 DMG cell populations and identify a mitotic oligodendroglial-lineage niche.

152 GSC differentiation towards the neuronal and oligodendroglial lineages is largely unknown.

153 th concurrent suppression of the neuronal or oligodendroglial lineages, or both.

154 developmental trajectories in astroglial and oligodendroglial lineages.

155 Importantly, ongoing oligodendroglial lipid degradation feeds rapidly into wh

156 the present study, we report that continuous oligodendroglial lipid metabolism provides an energy res

157 roxide production, mitochondrial injury, and oligodendroglial loss occurred in fetal brains exhibitin

158 140a(+) cells revealed overexpression of the oligodendroglial marker CD9, suggesting that CD9(+)/CD14

159 oth beta-tubulin- (neuronal marker) and O4- (oligodendroglial marker) immunoreactive cells and reduce

160 ransplantation into adult brain, neuronal or oligodendroglial markers segregated into distinct nonove

161 nside the CC lining started to express other oligodendroglial markers such as CNPase, RIP, and APC.

162 ker was the transcription factor SOX1; early oligodendroglial markers were chondroitin sulfate proteo

163 n and double-immunostained for ubiquitin and oligodendroglial markers, but not glial fibrillary acidi

164 ividing cells expressed mature astrocyte and oligodendroglial markers.

165 ro studies revealed that 5hmC is lost during oligodendroglial maturation but not microglial activatio

166 coupled receptor that has been identified as oligodendroglial maturation inhibitor because its stimul

167 ic effects of glutathione depletion and that oligodendroglial maturation is associated with decreased

168 Although oligodendroglial maturation of classical OL progenitor c

169 of the developing white matter by promoting oligodendroglial maturation, myelination, and functional

170 oles for axoglial interactions in regulating oligodendroglial maturation.

171 ve analysis, encapsulating both neuronal and oligodendroglial maturation.

172 hic lateral sclerosis, suggesting a role for oligodendroglial MCT1 in pathogenesis.

173 HC class I and II reporter mice, we compared oligodendroglial MHC expression in neonatal, young adult

174 emaphorin 3A and 3F, already known to direct oligodendroglial migration in development, may also be a

175 For example, genetic ablation of key oligodendroglial molecules abrogates the oligodendrocyte

176 Species-dependent diversity of oligodendroglial mRNA expression and myelin protein comp

177 These results suggest that oligodendroglial myelination is not only important for m

178 The role and mechanism of HIFa in oligodendroglial myelination, which is severely disturbe

179 The role and mechanism of HIFalpha in oligodendroglial myelination, which is severely disturbe

180 kodystrophy resulting from deficiency of the oligodendroglial NAA-cleaving enzyme aspartoacylase.

181 WHO 2000 grading criteria for high-grade oligodendroglial neoplasms [anaplastic oligoastrocytoma

182 Oligodendroglial neoplasms are a subgroup of gliomas wit

183 p12-15, and 10q22-26 and p53 mutation in 100 oligodendroglial neoplasms diagnosed at a single treatme

184 genotype and histological growth patterns of oligodendroglial neoplasms in association with MR imagin

185 These findings demonstrate that oligodendroglial neoplasms usually have loss of 1p and 1

186 Oligodendroglial neoplasms with the -1p/-19q genotype ar

187 ach to aid diagnosis and prognostication for oligodendroglial neoplasms.

188 ults suggest that trans interactions between oligodendroglial NF-155 and axonal ligands result in cro

189 Pharmacological studies have suggested that oligodendroglial NMDA glutamate receptors (NMDARs) media

190 Here we show that the stimulation of oligodendroglial NMDA receptors mobilizes glucose transp

191 ve deletion of NR3A, a modulatory subunit of oligodendroglial NMDARs, did not alter the course of MOG

192 We found that selective ablation of oligodendroglial NR1 did not alter the clinical severity

193 re there significant differences between the oligodendroglial NR1 KO and non-KO mice in numbers of ax

194 human MS, by timed conditional disruption of oligodendroglial NR1, an essential subunit of functional

195 rentiation by cultured EZCs without altering oligodendroglial or neuronal differentiation.

196 issues and cell lines of both astrocytic and oligodendroglial origin.

197 tamate homeostasis contributes to axonal and oligodendroglial pathology in MS.

198 atty acid beta-oxidation in mitochondria and oligodendroglial peroxisomes protects axons from conduct

199 he source of a small number of cells with an oligodendroglial phenotype during postnatal development

200 The oligodendroglial phenotype was highly associated with lo

201 fferentiation into neuronal, astroglial, and oligodendroglial phenotypes.

202 differentiation of cells with astroglial and oligodendroglial phenotypes.

203 Activity-regulated oligodendroglial plasticity also contributes to cognitiv

204 However, the relevance of oligodendroglial plasticity to neurological dysfunction

205 nduced by K-RAS and AKT and compared them to oligodendroglial platelet-derived growth factor B-induce

206 etrovirus type W (HERV-W) negatively affects oligodendroglial precursor cell (OPC) differentiation an

207 ed microRNA (miR) delivery method to control oligodendroglial precursor cell (OPC) differentiation th

208 decreased in the TMEM106B-deficient Oli-neu oligodendroglial precursor cell line.

209 due to dysregulation of ganglioside-mediated oligodendroglial precursor cell proliferation.

210 iating NSCs resulted in maturation-resistant oligodendroglial precursor cells (OPC), a cell populatio

211 receptors mediate hypoxic-ischemic injury to oligodendroglial precursor cells (OPCs) in a model of PV

212 The ability to isolate oligodendroglial precursor cells (OPCs) provides a power

213 resent in close proximity to TLR4-expressing oligodendroglial precursor cells adjacent to multiple sc

214 Human and rat oligodendroglial precursor cells expressed TLR4, and the

215 NV receptor, Toll-like receptor 4 (TLR4), on oligodendroglial precursor cells in human brain tissue a

216 Differentiation of oligodendroglial precursor cells is crucial for central

217 Cultured primary oligodendroglial precursor cells were stimulated with EN

218 ogenic effect on normal neural precursor and oligodendroglial precursor cells, the putative cellular

219 lt of activation and recruitment of resident oligodendroglial precursor cells.

220 to disturb myelin repair by interfering with oligodendroglial precursor differentiation and by polari

221 , resulting from both transgene induction in oligodendroglial precursors and the birth of new cells.

222 ode in late embryogenesis, and astrocyte and oligodendroglial precursors fail to appear.

223 riatal cells were mature oligodendrocytes or oligodendroglial precursors that were intrinsic to the s

224 of fetal astrocytes and, to a lesser extent, oligodendroglial precursors.

225 before the establishment of interneurons and oligodendroglial precursors.

226 enerated cells expressing Sox10, a marker of oligodendroglial precursors.

227 Nodal proteins and migrating oligodendroglial processes are no longer juxtaposed, and

228 +-dependent detachment and disintegration of oligodendroglial processes in the white matter of mice e

229 sion complex at the extremities of migrating oligodendroglial processes promotes process convergence

230 /kainate receptors, and preventing injury to oligodendroglial processes required the blocking of NMDA

231 ro, demonstrating that enhanced expansion of oligodendroglial processes requires signaling by extrace

232 broad zones within gaps between neighbouring oligodendroglial processes, and then are condensed into

233 Axons ensheathed by oligodendroglial processes, but not yet myelinated, were

234 partic acid) receptors located on peripheral oligodendroglial processes.

235 ormation but allow wrapping of some axons by oligodendroglial processes.

236 Oligodendroglial production within these clones is stimu

237 etermined that APC enhances proliferation of oligodendroglial progenitor cells (OPCs) and is essentia

238 Previous studies have shown that oligodendroglial progenitor cells (OPCs) can give rise t

239 rn mouse CNS is restricted to NG2-expressing oligodendroglial progenitor cells and oligodendrocytes.

240 Further, while oligodendroglial progenitor cells derived from cortical

241 hanced survival and maturation of newly born oligodendroglial progenitor cells in the normal corpus c

242 dendroglial development and is essential for oligodendroglial progenitor specification and differenti

243 into lineage-restricted progenitors such as oligodendroglial progenitors (OPs).

244 In contrast, oligodendroglial progenitors and microglial cells were u

245 (and LacZ-transfected), magnetically labeled oligodendroglial progenitors can be readily detected in

246 ive inflammatory microglia, and NG2 positive oligodendroglial progenitors in the hypoperfused corpus

247 ophin-3 (NT-3), primary cultures of cortical oligodendroglial progenitors were responsive to PDGF but

248 stage-specific IFNG-induced cytotoxicity in oligodendroglial progenitors.

249 r dual neuronal/astroglial identity and lack oligodendroglial programs, actively repressed by GSX2/DL

250 otype, and BDNF exerts distinct effects upon oligodendroglial proliferation, differentiation, and mye

251 identified as an actin cytoskeleton-related oligodendroglial protein in the rat central nervous syst

252 the normal corpus callosum, and accelerated oligodendroglial regeneration in lysolecithin-induced co

253 ions correlated with a dramatic reduction of oligodendroglial repopulation in the demyelinated lesion

254 n in APP/PS1 mice, reminiscent of the robust oligodendroglial response to demyelination.

255 ial differentiation and abrogates the normal oligodendroglial response to neuronal activity, leading

256 Interruption of oligodendroglial signaling to axons in Shiverer mutant m

257 endence of both axonal Robo1 positioning and oligodendroglial Slit2 production on cell-type-specific

258 Using RNA-sequencing, we identified oligodendroglial-specific responses to hypoxic brain inj

259 fate of cholesterol from damaged myelin and oligodendroglial sterol synthesis.

260 cture and suggests that axonal dependence on oligodendroglial support can become fatal when myelin is

261 ned that autoimmune inflammation may disrupt oligodendroglial support mechanisms and hence primarily

262 indicate that myelinated axons require local oligodendroglial support.

263 nti-proliferative, astroglial-inductive, and oligodendroglial-suppressive effects of BMP2.

264 only by neuronal but also by astroglial and oligodendroglial tau accumulation.

265 Oligodendroglial tau aggregates propagated along white m

266 au and CBD-tau strains induce astroglial and oligodendroglial tau inclusions, recapitulating the dive

267 igodendroglial tau, where the high degree of oligodendroglial tau pathology might affect neuronal int

268 While oligodendroglial tau pathology propagated across the mou

269 stronger for neuronal than for astroglial or oligodendroglial tau, suggesting that connectivity is pr

270 gression appeared to be determined mostly by oligodendroglial tau, where the high degree of oligodend

271 Here we demonstrate that oligodendroglial TNFR2 is a key mediator of tmTNF-depend

272 gamma signaling was associated with enhanced oligodendroglial tropism and delayed virus clearance.

273 We sequenced the CIC gene on 127 oligodendroglial tumors (109 with the 1p19q codeletion)

274 d point has already been reported.Anaplastic oligodendroglial tumors (AOTs) are chemotherapy-sensitiv

275 Remarkably, 9 of 10 murine oligodendroglial tumors (from p53+/- or ink4a/arf+/- ani

276 ificant associations of rs55705857 were with oligodendroglial tumors and gliomas with mutant IDH1 or

277 supplement 1p/19q prognostic information in oligodendroglial tumors and screen out cases that would

278 the potential to develop both astrocytic and oligodendroglial tumors given loss of p19(Arf), and that

279 g knowledge of the molecular pathogenesis of oligodendroglial tumors has spurred translational resear

280 Astrocytic and oligodendroglial tumors represent the two most common gr

281 Oligodendroglial tumors showed frequent loss of heterozy

282 ult patients with newly diagnosed anaplastic oligodendroglial tumors were randomly assigned to either

283 H mutational status identified patients with oligodendroglial tumors who did (and did not) benefit fr

284 Patients with 1p/19q codeleted anaplastic oligodendroglial tumors who participated in RTOG (Radiat

285 In patients with anaplastic oligodendroglial tumors with 1p/19q codeletion, probable

286 CIC gene is frequently mutated in oligodendroglial tumors with 1p19q codeletion.

287 ith IDH1-mutated and IDH2-mutated tumors and oligodendroglial tumors, albeit the specific mechanism o

288 genetic events differ between astrocytic and oligodendroglial tumors, but all tumors have an initiall

289 f RT increases both OS and PFS in anaplastic oligodendroglial tumors.

290 differ between grade-matched astrocytic and oligodendroglial tumors.

291 mor tissues and between GBMs and lower-grade oligodendroglial tumors.

292 of OLIG markers to augment identification of oligodendroglial tumors.

293 rvival with chemotherapy is not explained by oligodendroglial tumors.

294 also be the cell of origin for experimental oligodendroglial tumors.

295 vincristine (PCV) chemotherapy in anaplastic oligodendroglial tumors.

296 This study identified a group of oligodendroglial tumours with intact 1p/19q displaying d

297 Recent studies have indicated oligodendroglial-vascular crosstalk during brain develop

298 Evidence for this defective oligodendroglial-vascular interaction in MS suggests tha

299 The roles of oligodendroglial voltage-activated Na(+) channels (Nav)

300 cy is highly influenced by the cell context (oligodendroglial vs. global expression), the presence of